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Articles published in Acta Neuropathol

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    June 2017
  1. MCALEESE KE, Walker L, Graham S, Moya ELJ, et al
    Parietal white matter lesions in Alzheimer's disease are associated with cortical neurodegenerative pathology, but not with small vessel disease.
    Acta Neuropathol. 2017 Jun 21. doi: 10.1007/s00401-017-1738.
    PubMed     Text format     Abstract available


  2. LACAMPAGNE A, Liu X, Reiken S, Bussiere R, et al
    Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.
    Acta Neuropathol. 2017 Jun 19. doi: 10.1007/s00401-017-1733.
    PubMed     Text format     Abstract available


  3. HAURE-MIRANDE JV, Audrain M, Fanutza T, Kim SH, et al
    Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer's pathology.
    Acta Neuropathol. 2017 Jun 13. doi: 10.1007/s00401-017-1737.
    PubMed     Text format     Abstract available


    May 2017
  4. JIN WS, Shen LL, Bu XL, Zhang WW, et al
    Peritoneal dialysis reduces amyloid-beta plasma levels in humans and attenuates Alzheimer-associated phenotypes in an APP/PS1 mouse model.
    Acta Neuropathol. 2017 May 5. doi: 10.1007/s00401-017-1721.
    PubMed     Text format     Abstract available


  5. PASCUAL G, Wadia JS, Zhu X, Keogh E, et al
    Immunological memory to hyperphosphorylated tau in asymptomatic individuals.
    Acta Neuropathol. 2017;133:767-783.
    PubMed     Text format     Abstract available


  6. TAKAHASHI H, Klein ZA, Bhagat SM, Kaufman AC, et al
    Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network.
    Acta Neuropathol. 2017;133:785-807.
    PubMed     Text format     Abstract available


    April 2017
  7. DE ROECK A, Van den Bossche T, van der Zee J, Verheijen J, et al
    Deleterious ABCA7 mutations and transcript rescue mechanisms in early onset Alzheimer's disease.
    Acta Neuropathol. 2017 Apr 27. doi: 10.1007/s00401-017-1714.
    PubMed     Text format     Abstract available


    March 2017
  8. DURAN-ANIOTZ C, Cornejo VH, Espinoza S, Ardiles AO, et al
    IRE1 signaling exacerbates Alzheimer's disease pathogenesis.
    Acta Neuropathol. 2017 Mar 24. doi: 10.1007/s00401-017-1694.
    PubMed     Text format     Abstract available


  9. SUN M, Bell W, LaClair KD, Ling JP, et al
    Cryptic exon incorporation occurs in Alzheimer's brain lacking TDP-43 inclusion but exhibiting nuclear clearance of TDP-43.
    Acta Neuropathol. 2017 Mar 22. doi: 10.1007/s00401-017-1701.
    PubMed     Text format     Abstract available


  10. DRUMMOND E, Nayak S, Faustin A, Pires G, et al
    Proteomic differences in amyloid plaques in rapidly progressive and sporadic Alzheimer's disease.
    Acta Neuropathol. 2017 Mar 4. doi: 10.1007/s00401-017-1691.
    PubMed     Text format     Abstract available


    February 2017
  11. DEMING Y, Li Z, Kapoor M, Harari O, et al
    Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.
    Acta Neuropathol. 2017 Feb 28. doi: 10.1007/s00401-017-1685.
    PubMed     Text format     Abstract available


    January 2017
  12. ZENG J, Chen L, Wang Z, Chen Q, et al
    Marginal vitamin A deficiency facilitates Alzheimer's pathogenesis.
    Acta Neuropathol. 2017 Jan 27. doi: 10.1007/s00401-017-1669.
    PubMed     Text format     Abstract available


    December 2016
  13. DRUMMOND E, Wisniewski T
    Alzheimer's disease: experimental models and reality.
    Acta Neuropathol. 2016 Dec 26. doi: 10.1007/s00401-016-1662.
    PubMed     Text format     Abstract available


  14. CHAPUIS J, Flaig A, Grenier-Boley B, Eysert F, et al
    Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


    November 2016
  15. RAMOS-MIGUEL A, Sawada K, Jones AA, Thornton AE, et al
    Presynaptic proteins complexin-I and complexin-II differentially influence cognitive function in early and late stages of Alzheimer's disease.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


    October 2016
  16. LACLAIR KD, Donde A, Ling JP, Jeong YH, et al
    Depletion of TDP-43 decreases fibril and plaque beta-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


  17. KOSS DJ, Jones G, Cranston A, Gardner H, et al
    Soluble pre-fibrillar tau and beta-amyloid species emerge in early human Alzheimer's disease and track disease progression and cognitive decline.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


  18. SANCHEZ-MEJIAS E, Navarro V, Jimenez S, Sanchez-Mico M, et al
    Soluble phospho-tau from Alzheimer's disease hippocampus drives microglial degeneration.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


    September 2016
  19. HART NJ, Koronyo Y, Black KL, Koronyo-Hamaoui M, et al
    Ocular indicators of Alzheimer's: exploring disease in the retina.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


  20. ANDERSEN OM, Rudolph IM, Willnow TE
    Risk factor SORL1: from genetic association to functional validation in Alzheimer's disease.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


    August 2016
  21. KLEIN HU, Bennett DA, De Jager PL
    The epigenome in Alzheimer's disease: current state and approaches for a new path to gene discovery and understanding disease mechanism.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


    July 2016
  22. GU BJ, Huang X, Ou A, Rembach A, et al
    Innate phagocytosis by peripheral blood monocytes is altered in Alzheimer's disease.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


    May 2016
  23. SHINOHARA M, Murray ME, Frank RD, Shinohara M, et al
    Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer's disease.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


    April 2016
  24. KALARIA RN
    Neuropathological diagnosis of vascular cognitive impairment and vascular dementia with implications for Alzheimer's disease.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


  25. MONTAGNE A, Nation DA, Pa J, Sweeney MD, et al
    Brain imaging of neurovascular dysfunction in Alzheimer's disease.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


  26. KUMAR S, Wirths O, Stuber K, Wunderlich P, et al
    Phosphorylation of the amyloid beta-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity.
    Acta Neuropathol. 2016;131:525-37.
    PubMed     Text format     Abstract available


    March 2016
  27. VERHEIJEN J, Van den Bossche T, van der Zee J, Engelborghs S, et al
    A comprehensive study of the genetic impact of rare variants in SORL1 in European early-onset Alzheimer's disease.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


  28. SADLEIR KR, Kandalepas PC, Buggia-Prevot V, Nicholson DA, et al
    Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Abeta generation in Alzheimer's disease.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


  29. MERLINI M, Wanner D, Nitsch RM
    Tau pathology-dependent remodelling of cerebral arteries precedes Alzheimer's disease-related microvascular cerebral amyloid angiopathy.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


    January 2016
  30. JOSEPHS KA, Murray ME, Whitwell JL, Tosakulwong N, et al
    Updated TDP-43 in Alzheimer's disease staging scheme.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


  31. PICCIO L, Deming Y, Del-Aguila JL, Ghezzi L, et al
    Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


  32. ZOU C, Shi Y, Ohli J, Schuller U, et al
    Neuroinflammation impairs adaptive structural plasticity of dendritic spines in a preclinical model of Alzheimer's disease.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


  33. EISELE YS, Duyckaerts C
    Propagation of Ass pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies.
    Acta Neuropathol. 2016;131:5-25.
    PubMed     Text format     Abstract available


  34. MCKEE AC, Cairns NJ, Dickson DW, Folkerth RD, et al
    The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy.
    Acta Neuropathol. 2016;131:75-86.
    PubMed     Text format     Abstract available


    December 2015
  35. TOLEDO JB, Gopal P, Raible K, Irwin DJ, et al
    Pathological alpha-synuclein distribution in subjects with coincident Alzheimer's and Lewy body pathology.
    Acta Neuropathol. 2015.
    PubMed     Text format     Abstract available


  36. LOVE S, Miners JS
    Cerebrovascular disease in ageing and Alzheimer's disease.
    Acta Neuropathol. 2015.
    PubMed     Text format     Abstract available


  37. ST-AMOUR I, Cicchetti F, Calon F
    Immunotherapies in Alzheimer's disease: Too much, too little, too late or off-target?
    Acta Neuropathol. 2015.
    PubMed     Text format     Abstract available


    November 2015
  38. FOL R, Braudeau J, Ludewig S, Abel T, et al
    Viral gene transfer of APPsalpha rescues synaptic failure in an Alzheimer's disease mouse model.
    Acta Neuropathol. 2015.
    PubMed     Text format     Abstract available


    October 2015
  39. WONG H, Levenga J, Cain P, Rothermel B, et al
    RCAN1 overexpression promotes age-dependent mitochondrial dysregulation related to neurodegeneration in Alzheimer's disease.
    Acta Neuropathol. 2015.
    PubMed     Text format     Abstract available


  40. BOUTER Y, Noguerola JS, Tucholla P, Crespi GA, et al
    Abeta targets of the biosimilar antibodies of Bapineuzumab, Crenezumab, Solanezumab in comparison to an antibody against N-truncated Abeta in sporadic Alzheimer disease cases and mouse models.
    Acta Neuropathol. 2015.
    PubMed     Text format     Abstract available


  41. XIANG Y, Bu XL, Liu YH, Zhu C, et al
    Physiological amyloid-beta clearance in the periphery and its therapeutic potential for Alzheimer's disease.
    Acta Neuropathol. 2015;130:487-99.
    PubMed     Text format     Abstract available


    August 2015
  42. ARENDT T, Bruckner MK, Losche A
    Regional mosaic genomic heterogeneity in the elderly and in Alzheimer's disease as a correlate of neuronal vulnerability.
    Acta Neuropathol. 2015.
    PubMed     Text format     Abstract available


    July 2015
  43. DOROSTKAR MM, Zou C, Blazquez-Llorca L, Herms J, et al
    Analyzing dendritic spine pathology in Alzheimer's disease: problems and opportunities.
    Acta Neuropathol. 2015;130:1-19.
    PubMed     Text format     Abstract available


    January 2015
  44. NHAN HS, Chiang K, Koo EH
    The multifaceted nature of amyloid precursor protein and its proteolytic fragments: friends and foes.
    Acta Neuropathol. 2015;129:1-19.
    PubMed     Text format     Abstract available


    October 2014
  45. FRITSCHI SK, Cintron A, Ye L, Mahler J, et al
    Abeta seeds resist inactivation by formaldehyde.
    Acta Neuropathol. 2014;128:477-84.
    PubMed     Text format     Abstract available


  46. BOLUDA S, Toledo JB, Irwin DJ, Raible KM, et al
    A comparison of Abeta amyloid pathology staging systems and correlation with clinical diagnosis.
    Acta Neuropathol. 2014;128:543-50.
    PubMed     Text format     Abstract available


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