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  Alzheimer's Disease

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Articles published in J Neurosci

Retrieve available abstracts of 45 articles:
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Single Articles


    June 2017
  1. ZHANG S, Wang Z, Cai F, Zhang M, et al
    BACE1 cleavage site selection critical for amyloidogenesis and Alzheimer's pathogenesis.
    J Neurosci. 2017 Jun 16. pii: 0340-17. doi: 10.1523/JNEUROSCI.0340-17.2017.
    PubMed     Text format     Abstract available


  2. DINIZ LP, Tortelli V, Matias I, Morgado J, et al
    Astrocyte transforming growth factor beta 1 protects synapses against Abeta oligomers in Alzheimer's disease model.
    J Neurosci. 2017 Jun 12. pii: 3351-16. doi: 10.1523/JNEUROSCI.3351-16.2017.
    PubMed     Text format     Abstract available


    May 2017
  3. SELLES MC, Fortuna JTS, Santos LE
    Immunomodulation via Toll-like Receptor 9: An Adjunct Therapy Strategy against Alzheimer's Disease?
    J Neurosci. 2017;37:4864-4867.
    PubMed     Text format    


  4. ROYEA J, Zhang L, Tong XK, Hamel E, et al
    Angiotensin IV receptors mediate the cognitive and cerebrovascular benefits of losartan in a mouse model of Alzheimer's disease.
    J Neurosci. 2017 May 5. pii: 0329-17. doi: 10.1523/JNEUROSCI.0329-17.2017.
    PubMed     Text format     Abstract available


    April 2017
  5. GAMAGE KK, Kumar S
    Aducanumab Therapy Ameliorates Calcium Overload in a Mouse Model of Alzheimer's Disease.
    J Neurosci. 2017;37:4430-4432.
    PubMed     Text format    


  6. BAEK SH, Park SJ, In Jeong J, Hyun Kim S, et al
    Inhibition of Drp1 Ameliorates Synaptic Depression, Abeta Deposition and Cognitive Impairment in Alzheimer's Disease Model.
    J Neurosci. 2017 Apr 21. pii: 2385-16. doi: 10.1523/JNEUROSCI.2385-16.2017.
    PubMed     Text format     Abstract available


    March 2017
  7. GRATTON C, Yousef S, Aarts E, Wallace DL, et al
    Cholinergic, but not dopaminergic or noradrenergic, enhancement sharpens visual spatial perception in humans.
    J Neurosci. 2017 Mar 23. pii: 2405-16. doi: 10.1523/JNEUROSCI.2405-16.2017.
    PubMed     Text format     Abstract available


    February 2017
  8. YE X, Feng T, Tammineni P, Chang Q, et al
    Regulation of Synaptic Abeta Generation Through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
    J Neurosci. 2017 Feb 3. pii: 2851-16. doi: 10.1523/JNEUROSCI.2851-16.2017.
    PubMed     Text format     Abstract available


    January 2017
  9. ZHANG ZH, Wu QY, Zheng R, Chen C, et al
    Selenomethionine mitigates cognitive decline by targeting both tau hyperphosphorylation and autophagic clearance in an Alzheimer's disease mouse model.
    J Neurosci. 2017 Jan 30. pii: 3229-16. doi: 10.1523/JNEUROSCI.3229-16.2017.
    PubMed     Text format     Abstract available


  10. JAY TR, Hirsch AM, Broihier ML, Miller CM, et al
    Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease.
    J Neurosci. 2017;37:637-647.
    PubMed     Text format     Abstract available


  11. VIEIRA MN, Beckman D
    Training Microglia to Resist Alzheimer's Disease.
    J Neurosci. 2017;37:477-479.
    PubMed     Text format    


  12. DATTA D
    APP Modulates Abeta-Induced Activation of Microglia in Mouse Model of Alzheimer's Disease.
    J Neurosci. 2017;37:238-240.
    PubMed     Text format    


  13. YANG T, Li S, Xu H, Walsh DM, et al
    Large Soluble Oligomers of Amyloid beta-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate.
    J Neurosci. 2017;37:152-163.
    PubMed     Text format     Abstract available


    December 2016
  14. PRIETO GA, Trieu BH, Dang CT, Bilousova T, et al
    Pharmacological rescue of long-term potentiation in Alzheimer diseased synapses.
    J Neurosci. 2016 Dec 16. pii: 2774.
    PubMed     Text format     Abstract available


  15. JAY TR, Hirsch AM, Broihier ML, Miller CM, et al
    Disease progression-dependent effects of TREM2 deficiency in a mouse model of Alzheimer's disease.
    J Neurosci. 2016 Dec 9. pii: 2110.
    PubMed     Text format     Abstract available


    November 2016
  16. LEDO JH, Azevedo EP, Beckman D, Ribeiro FC, et al
    Cross Talk Between Brain Innate Immunity and Serotonin Signaling Underlies Depressive-Like Behavior Induced by Alzheimer's Amyloid-beta Oligomers in Mice.
    J Neurosci. 2016;36:12106-12116.
    PubMed     Text format     Abstract available


  17. SHI XD, Sun K, Hu R, Liu XY, et al
    Blocking the Interaction between EphB2 and ADDLs by a Small Peptide Rescues Impaired Synaptic Plasticity and Memory Deficits in a Mouse Model of Alzheimer's Disease.
    J Neurosci. 2016;36:11959-11973.
    PubMed     Text format     Abstract available


  18. ZHANG H, Sun S, Wu L, Pchitskaya E, et al
    Store-Operated Calcium Channel Complex in Postsynaptic Spines: A New Therapeutic Target for Alzheimer's Disease Treatment.
    J Neurosci. 2016;36:11837-11850.
    PubMed     Text format     Abstract available


    October 2016
  19. SHU S, Zhu H, Tang N, Chen W, et al
    Selective Degeneration of Entorhinal-CA1 Synapses in Alzheimer's Disease via Activation of DAPK1.
    J Neurosci. 2016;36:10843-10852.
    PubMed     Text format     Abstract available


    September 2016
  20. SAITO T, Matsuba Y, Yamazaki N, Hashimoto S, et al
    Calpain Activation in Alzheimer's Model Mice Is an Artifact of APP and Presenilin Overexpression.
    J Neurosci. 2016;36:9933-6.
    PubMed     Text format     Abstract available


    August 2016
  21. DINKINS MB, Enasko J, Hernandez C, Wang G, et al
    Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer's Disease Pathology and Improves Cognition in the 5XFAD Mouse.
    J Neurosci. 2016;36:8653-67.
    PubMed     Text format     Abstract available


  22. MANOCHA GD, Floden AM, Rausch K, Kulas JA, et al
    APP Regulates Microglial Phenotype in a Mouse Model of Alzheimer's Disease.
    J Neurosci. 2016;36:8471-86.
    PubMed     Text format     Abstract available


    July 2016
  23. SPENCER B, Desplats PA, Overk CR, Valera-Martin E, et al
    Reducing Endogenous alpha-Synuclein Mitigates the Degeneration of Selective Neuronal Populations in an Alzheimer's Disease Transgenic Mouse Model.
    J Neurosci. 2016;36:7971-84.
    PubMed     Text format     Abstract available


    March 2016
  24. SAKAE N, Liu CC, Shinohara M, Frisch-Daiello J, et al
    ABCA7 Deficiency Accelerates Amyloid-beta Generation and Alzheimer's Neuronal Pathology.
    J Neurosci. 2016;36:3848-59.
    PubMed     Text format     Abstract available


  25. JAOUEN F, Gascon E
    Understanding the Role of miR-33 in Brain Lipid Metabolism: Implications for Alzheimer's Disease.
    J Neurosci. 2016;36:2558-60.
    PubMed     Text format    


    January 2016
  26. OLIVEIRA MM, Lourenco MV
    Integrated Stress Response: Connecting ApoE4 to Memory Impairment in Alzheimer's Disease.
    J Neurosci. 2016;36:1053-5.
    PubMed     Text format    


  27. MEIER S, Bell M, Lyons DN, Rodriguez-Rivera J, et al
    Pathological Tau Promotes Neuronal Damage by Impairing Ribosomal Function and Decreasing Protein Synthesis.
    J Neurosci. 2016;36:1001-7.
    PubMed     Text format     Abstract available


  28. LIAN H, Litvinchuk A, Chiang AC, Aithmitti N, et al
    Astrocyte-Microglia Cross Talk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease.
    J Neurosci. 2016;36:577-89.
    PubMed     Text format     Abstract available


  29. YUAN P, Grutzendler J
    Attenuation of beta-Amyloid Deposition and Neurotoxicity by Chemogenetic Modulation of Neural Activity.
    J Neurosci. 2016;36:632-41.
    PubMed     Text format     Abstract available


    December 2015
  30. FERRIER J, Bayet-Robert M, Dalmann R, El Guerrab A, et al
    Cholinergic Neurotransmission in the Posterior Insular Cortex Is Altered in Preclinical Models of Neuropathic Pain: Key Role of Muscarinic M2 Receptors in Donepezil-Induced Antinociception.
    J Neurosci. 2015;35:16418-16430.
    PubMed     Text format     Abstract available


    November 2015
  31. LIU B, Le KX, Park MA, Wang S, et al
    In Vivo Detection of Age- and Disease-Related Increases in Neuroinflammation by 18F-GE180 TSPO MicroPET Imaging in Wild-Type and Alzheimer's Transgenic Mice.
    J Neurosci. 2015;35:15716-30.
    PubMed     Text format     Abstract available


  32. RAPPAPORT AN, Jacob E, Sharma V, Inberg S, et al
    Expression of Quinone Reductase-2 in the Cortex Is a Muscarinic Acetylcholine Receptor-Dependent Memory Consolidation Constraint.
    J Neurosci. 2015;35:15568-81.
    PubMed     Text format     Abstract available


  33. OSTAPCHENKO VG, Chen M, Guzman MS, Xie YF, et al
    The Transient Receptor Potential Melastatin 2 (TRPM2) Channel Contributes to beta-Amyloid Oligomer-Related Neurotoxicity and Memory Impairment.
    J Neurosci. 2015;35:15157-69.
    PubMed     Text format     Abstract available


    October 2015
  34. CACCAMO A, Branca C, Talboom JS, Shaw DM, et al
    Reducing Ribosomal Protein S6 Kinase 1 Expression Improves Spatial Memory and Synaptic Plasticity in a Mouse Model of Alzheimer's Disease.
    J Neurosci. 2015;35:14042-56.
    PubMed     Text format     Abstract available


    September 2015
  35. ZHANG H, Wu L, Pchitskaya E, Zakharova O, et al
    Neuronal Store-Operated Calcium Entry and Mushroom Spine Loss in Amyloid Precursor Protein Knock-In Mouse Model of Alzheimer's Disease.
    J Neurosci. 2015;35:13275-86.
    PubMed     Text format     Abstract available


  36. SEGEV Y, Barrera I, Ounallah-Saad H, Wibrand K, et al
    PKR Inhibition Rescues Memory Deficit and ATF4 Overexpression in ApoE epsilon4 Human Replacement Mice.
    J Neurosci. 2015;35:12986-93.
    PubMed     Text format     Abstract available


  37. PROULX E, Fraser P, McLaurin J, Lambe EK, et al
    Impaired Cholinergic Excitation of Prefrontal Attention Circuitry in the TgCRND8 Model of Alzheimer's Disease.
    J Neurosci. 2015;35:12779-91.
    PubMed     Text format     Abstract available


  38. GILLEBERT CR, Schaeverbeke J, Bastin C, Neyens V, et al
    3D Shape Perception in Posterior Cortical Atrophy: A Visual Neuroscience Perspective.
    J Neurosci. 2015;35:12673-92.
    PubMed     Text format     Abstract available


    August 2015
  39. GONTIER G, George C, Chaker Z, Holzenberger M, et al
    Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-beta Clearance.
    J Neurosci. 2015;35:11500-13.
    PubMed     Text format     Abstract available


  40. SHAW JL, Zhang S, Chang KT
    Bidirectional Regulation of Amyloid Precursor Protein-Induced Memory Defects by Nebula/DSCR1: A Protein Upregulated in Alzheimer's Disease and Down Syndrome.
    J Neurosci. 2015;35:11374-83.
    PubMed     Text format     Abstract available


  41. MEGILL A, Tran T, Eldred K, Lee NJ, et al
    Defective Age-Dependent Metaplasticity in a Mouse Model of Alzheimer's Disease.
    J Neurosci. 2015;35:11346-57.
    PubMed     Text format     Abstract available


    July 2015
  42. BESSON FL, La Joie R, Doeuvre L, Gaubert M, et al
    Cognitive and Brain Profiles Associated with Current Neuroimaging Biomarkers of Preclinical Alzheimer's Disease.
    J Neurosci. 2015;35:10402-11.
    PubMed     Text format     Abstract available


    June 2015
  43. HARCHA PA, Vargas A, Yi C, Koulakoff AA, et al
    Hemichannels Are Required for Amyloid beta-Peptide-Induced Degranulation and Are Activated in Brain Mast Cells of APPswe/PS1dE9 Mice.
    J Neurosci. 2015;35:9526-38.
    PubMed     Text format     Abstract available


  44. CASALI BT, Corona AW, Mariani MM, Karlo JC, et al
    Omega-3 Fatty Acids Augment the Actions of Nuclear Receptor Agonists in a Mouse Model of Alzheimer's Disease.
    J Neurosci. 2015;35:9173-81.
    PubMed     Text format     Abstract available


    May 2015
  45. SEN A, Nelson TJ, Alkon DL
    ApoE4 and Abeta Oligomers Reduce BDNF Expression via HDAC Nuclear Translocation.
    J Neurosci. 2015;35:7538-51.
    PubMed     Text format     Abstract available


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