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  Alzheimer's Disease

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Articles published in Neurobiol Aging

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    April 2017
  1. SONNI I, Ratib O, Boccardi M, Picco A, et al
    Clinical validity of presynaptic dopaminergic imaging with 123I-ioflupane and noradrenergic imaging with 123I-MIBG in the differential diagnosis between Alzheimer's disease and dementia with Lewy bodies in the context of a structured 5-phase developme
    Neurobiol Aging. 2017;52:228-242.
    PubMed     Text format     Abstract available


  2. CHIOTIS K, Saint-Aubert L, Boccardi M, Gietl A, et al
    Clinical validity of increased cortical uptake of amyloid ligands on PET as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework.
    Neurobiol Aging. 2017;52:214-227.
    PubMed     Text format     Abstract available


  3. MATTSSON N, Lonneborg A, Boccardi M, Blennow K, et al
    Clinical validity of cerebrospinal fluid Abeta42, tau, and phospho-tau as biomarkers for Alzheimer's disease in the context of a structured 5-phase development framework.
    Neurobiol Aging. 2017;52:196-213.
    PubMed     Text format     Abstract available


  4. GARIBOTTO V, Herholz K, Boccardi M, Picco A, et al
    Clinical validity of brain fluorodeoxyglucose positron emission tomography as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework.
    Neurobiol Aging. 2017;52:183-195.
    PubMed     Text format     Abstract available


  5. TEN KATE M, Barkhof F, Boccardi M, Visser PJ, et al
    Clinical validity of medial temporal atrophy as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework.
    Neurobiol Aging. 2017;52:167-182.
    PubMed     Text format     Abstract available


  6. CERAMI C, Dubois B, Boccardi M, Monsch AU, et al
    Clinical validity of delayed recall tests as a gateway biomarker for Alzheimer's disease in the context of a structured 5-phase development framework.
    Neurobiol Aging. 2017;52:153-166.
    PubMed     Text format     Abstract available


  7. BOCCARDI M, Gallo V, Yasui Y, Vineis P, et al
    The biomarker-based diagnosis of Alzheimer's disease. 2-lessons from oncology.
    Neurobiol Aging. 2017;52:141-152.
    PubMed     Text format     Abstract available


  8. PORTERI C, Albanese E, Scerri C, Carrillo MC, et al
    The biomarker-based diagnosis of Alzheimer's disease. 1-ethical and societal issues.
    Neurobiol Aging. 2017;52:132-140.
    PubMed     Text format     Abstract available


  9. FRISONI GB, Perani D, Bastianello S, Bernardi G, et al
    Biomarkers for the diagnosis of Alzheimer's disease in clinical practice: an Italian intersocietal roadmap.
    Neurobiol Aging. 2017;52:119-131.
    PubMed     Text format     Abstract available


  10. FRISONI GB, Jack CR Jr, Winblad B
    Alzheimer's disease biomarker development: a call to funding bodies.
    Neurobiol Aging. 2017;52:117-118.
    PubMed     Text format    


    February 2017
  11. AZIZ AL, Giusiano B, Joubert S, Duprat L, et al
    Difference in imaging biomarkers of neurodegeneration between early and late-onset amnestic Alzheimer's disease.
    Neurobiol Aging. 2017;54:22-30.
    PubMed     Text format     Abstract available


  12. CHO H, Choi JY, Lee SH, Lee JH, et al
    Excessive tau accumulation in the parieto-occipital cortex characterizes early-onset Alzheimer's disease.
    Neurobiol Aging. 2017;53:103-111.
    PubMed     Text format     Abstract available


  13. MI Z, Abrahamson EE, Ryu AY, Fish KN, et al
    Loss of precuneus dendritic spines immunopositive for spinophilin is related to cognitive impairment in early Alzheimer's disease.
    Neurobiol Aging. 2017 Feb 4. pii: S0197-4580(17)30030.
    PubMed     Text format     Abstract available


    January 2017
  14. BRENOWITZ WD, Keene CD, Hawes SE, Hubbard RA, et al
    Alzheimer's disease neuropathologic change, Lewy body disease, and vascular brain injury in clinic- and community-based samples.
    Neurobiol Aging. 2017;53:83-92.
    PubMed     Text format     Abstract available


  15. LI GD, Bi R, Zhang DF, Xu M, et al
    Female-specific effect of the BDNF gene on Alzheimer's disease.
    Neurobiol Aging. 2017 Jan 24. pii: S0197-4580(16)30336.
    PubMed     Text format     Abstract available


  16. GABELLE A, Jaussent I, Hirtz C, Vialaret J, et al
    Cerebrospinal fluid levels of orexin-A and histamine, and sleep profile within the Alzheimer process.
    Neurobiol Aging. 2017;53:59-66.
    PubMed     Text format     Abstract available


  17. LUNNON K, Keohane A, Pidsley R, Newhouse S, et al
    Mitochondrial genes are altered in blood early in Alzheimer's disease.
    Neurobiol Aging. 2017;53:36-47.
    PubMed     Text format     Abstract available


  18. LOU F, Luo X, Li M, Ren Y, et al
    Very early-onset sporadic Alzheimer's disease with a de novo mutation in the PSEN1 gene.
    Neurobiol Aging. 2017 Jan 6. pii: S0197-4580(16)30339.
    PubMed     Text format     Abstract available


  19. RANASINGHE KG, Gill JS, Kothare H, Beagle AJ, et al
    Abnormal vocal behavior predicts executive and memory deficits in Alzheimer's disease.
    Neurobiol Aging. 2017;52:71-80.
    PubMed     Text format     Abstract available


    December 2016
  20. WANG Y, Veremeyko T, Wong AH, El Fatimy R, et al
    Downregulation of miR-132/212 impairs S-nitrosylation balance and induces tau phosphorylation in Alzheimer's disease.
    Neurobiol Aging. 2016 Dec 27. pii: S0197-4580(16)30328.
    PubMed     Text format     Abstract available


  21. CERVERA-CARLES L, Alcolea D, Estanga A, Ecay-Torres M, et al
    Cerebrospinal fluid mitochondrial DNA in the Alzheimer's disease continuum.
    Neurobiol Aging. 2016 Dec 22. pii: S0197-4580(16)30315.
    PubMed     Text format     Abstract available


  22. PONOMAREVA NV, Andreeva TV, Protasova MS, Shagam LI, et al
    Quantitative EEG during normal aging: association with the Alzheimer's disease genetic risk variant in PICALM gene.
    Neurobiol Aging. 2016 Dec 20. pii: S0197-4580(16)30316.
    PubMed     Text format     Abstract available


  23. KREISL WC, Lyoo CH, Liow JS, Snow J, et al
    Distinct patterns of increased translocator protein in posterior cortical atrophy and amnestic Alzheimer's disease.
    Neurobiol Aging. 2016;51:132-140.
    PubMed     Text format     Abstract available


  24. ESTANGA A, Ecay-Torres M, Ibanez A, Izagirre A, et al
    Beneficial effect of bilingualism on Alzheimer's disease CSF biomarkers and cognition.
    Neurobiol Aging. 2016 Dec 1. pii: S0197-4580(16)30253.
    PubMed     Text format     Abstract available


    November 2016
  25. HARACH T, Jammes F, Muller C, Duthilleul N, et al
    Administrations of human adult ischemia-tolerant mesenchymal stem cells and factors reduce amyloid beta pathology in a mouse model of Alzheimer's disease.
    Neurobiol Aging. 2016;51:83-96.
    PubMed     Text format     Abstract available


  26. MAPSTONE M, Lin F, Nalls MA, Cheema AK, et al
    What success can teach us about failure: the plasma metabolome of older adults with superior memory and lessons for Alzheimer's disease.
    Neurobiol Aging. 2016 Nov 21. pii: S0197-4580(16)30294.
    PubMed     Text format     Abstract available


  27. ESKILDSEN SF, Gyldensted L, Nagenthiraja K, Nielsen RB, et al
    Increased cortical capillary transit time heterogeneity in Alzheimer's disease: a DSC-MRI perfusion study.
    Neurobiol Aging. 2016;50:107-118.
    PubMed     Text format     Abstract available


  28. VIJVERBERG EG, Tijms BM, Dopp J, Hong YJ, et al
    Gray matter network differences between behavioral variant frontotemporal dementia and Alzheimer's disease.
    Neurobiol Aging. 2016;50:77-86.
    PubMed     Text format     Abstract available


  29. ZAHRATKA JA, Shao Y, Shaw M, Todd K, et al
    Regulatory region genetic variation is associated with FYN expression in Alzheimer's disease.
    Neurobiol Aging. 2016;51:43-53.
    PubMed     Text format     Abstract available


    October 2016
  30. MAINGRET V, Barthet G, Deforges S, Jiang N, et al
    PGE2-EP3 signaling pathway impairs hippocampal presynaptic long-term plasticity in a mouse model of Alzheimer's disease.
    Neurobiol Aging. 2016;50:13-24.
    PubMed     Text format     Abstract available


  31. SHEA YF, Chan AO, Chu LW, Lee SC, et al
    Novel presenilin 1 mutation (p.F386I) in a Chinese family with early-onset Alzheimer's disease.
    Neurobiol Aging. 2016 Oct 15. pii: S0197-4580(16)30255.
    PubMed     Text format     Abstract available


  32. ZHAN Y, Zheng H, Wang C, Rong Z, et al
    A novel presenilin 1 mutation (F388L) identified in a Chinese family with early-onset Alzheimer's disease.
    Neurobiol Aging. 2016 Oct 15. pii: S0197-4580(16)30250.
    PubMed     Text format     Abstract available


  33. TOURNISSAC M, Vandal M, Francois A, Planel E, et al
    Old age potentiates cold-induced tau phosphorylation: linking thermoregulatory deficit with Alzheimer's disease.
    Neurobiol Aging. 2016;50:25-29.
    PubMed     Text format     Abstract available


  34. NATELSON LOVE M, Clark DG, Cochran JN, Den Beste KA, et al
    Clinical, imaging, pathological, and biochemical characterization of a novel presenilin 1 mutation (N135Y) causing Alzheimer's disease.
    Neurobiol Aging. 2016 Oct 3. pii: S0197-4580(16)30234.
    PubMed     Text format     Abstract available


  35. PICHLER S, Gu W, Hartl D, Gasparoni G, et al
    The miRNome of Alzheimer's disease: consistent downregulation of the miR-132/212 cluster.
    Neurobiol Aging. 2016 Oct 3. pii: S0197-4580(16)30233.
    PubMed     Text format     Abstract available


    September 2016
  36. WOLK DA, Das SR, Mueller SG, Weiner MW, et al
    Medial temporal lobe subregional morphometry using high resolution MRI in Alzheimer's disease.
    Neurobiol Aging. 2016 Sep 30. pii: S0197-4580(16)30224.
    PubMed     Text format     Abstract available


  37. BARBER IS, Braae A, Clement N, Patel T, et al
    Mutation analysis of sporadic early-onset Alzheimer's disease using the NeuroX array.
    Neurobiol Aging. 2016 Sep 23. pii: S0197-4580(16)30221.
    PubMed     Text format     Abstract available


  38. MARIN R, Fabelo N, Martin V, Garcia-Esparcia P, et al
    Anomalies occurring in lipid profiles and protein distribution in frontal cortex lipid rafts in dementia with Lewy bodies disclose neurochemical traits partially shared by Alzheimer's and Parkinson's diseases.
    Neurobiol Aging. 2016;49:52-59.
    PubMed     Text format     Abstract available


  39. ROSHCHUPKIN GV, Adams HH, van der Lee SJ, Vernooij MW, et al
    Fine-mapping the effects of Alzheimer's disease risk loci on brain morphology.
    Neurobiol Aging. 2016;48:204-211.
    PubMed     Text format     Abstract available


    August 2016
  40. ROSA E, Mahendram S, Ke YD, Ittner LM, et al
    Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease.
    Neurobiol Aging. 2016;48:135-142.
    PubMed     Text format     Abstract available


  41. BABILONI C, Del Percio C, Caroli A, Salvatore E, et al
    Cortical sources of resting state EEG rhythms are related to brain hypometabolism in subjects with Alzheimer's disease: an EEG-PET study.
    Neurobiol Aging. 2016;48:122-134.
    PubMed     Text format     Abstract available


  42. KOLBE K, Bukhari H, Loosse C, Leonhardt G, et al
    Extensive nuclear sphere generation in the human Alzheimer's brain.
    Neurobiol Aging. 2016;48:103-113.
    PubMed     Text format     Abstract available


  43. NA HK, Kang DR, Kim S, Seo SW, et al
    Malignant progression in parietal-dominant atrophy subtype of Alzheimer's disease occurs independent of onset age.
    Neurobiol Aging. 2016;47:149-156.
    PubMed     Text format     Abstract available


  44. POTTIER C, Ravenscroft TA, Brown PH, Finch NA, et al
    TYROBP genetic variants in early-onset Alzheimer's disease.
    Neurobiol Aging. 2016 Aug 8. pii: S0197-4580(16)30165.
    PubMed     Text format     Abstract available


  45. ESCOTT-PRICE V, Shoai M, Pither R, Williams J, et al
    Polygenic score prediction captures nearly all common genetic risk for Alzheimer's disease.
    Neurobiol Aging. 2016 Aug 5. pii: S0197-4580(16)30155.
    PubMed     Text format     Abstract available


  46. ROSEN RF, Tomidokoro Y, Farberg AS, Dooyema J, et al
    Comparative pathobiology of beta-amyloid and the unique susceptibility of humans to Alzheimer's disease.
    Neurobiol Aging. 2016;44:185-96.
    PubMed     Text format     Abstract available


  47. ZHAO L, Gottesdiener AJ, Parmar M, Li M, et al
    Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models.
    Neurobiol Aging. 2016;44:159-72.
    PubMed     Text format     Abstract available


  48. DILLEN KN, Jacobs HI, Kukolja J, von Reutern B, et al
    Aberrant functional connectivity differentiates retrosplenial cortex from posterior cingulate cortex in prodromal Alzheimer's disease.
    Neurobiol Aging. 2016;44:114-26.
    PubMed     Text format     Abstract available


  49. HAZRA A, Corbett BF, You JC, Aschmies S, et al
    Corticothalamic network dysfunction and behavioral deficits in a mouse model of Alzheimer's disease.
    Neurobiol Aging. 2016;44:96-107.
    PubMed     Text format     Abstract available


  50. KREISL WC, Lyoo CH, Liow JS, Wei M, et al
    (11)C-PBR28 binding to translocator protein increases with progression of Alzheimer's disease.
    Neurobiol Aging. 2016;44:53-61.
    PubMed     Text format     Abstract available


  51. VOS SJ, Gordon BA, Su Y, Visser PJ, et al
    NIA-AA staging of preclinical Alzheimer disease: discordance and concordance of CSF and imaging biomarkers.
    Neurobiol Aging. 2016;44:1-8.
    PubMed     Text format     Abstract available


    July 2016
  52. COLLOBY SJ, Field RH, Wyper DJ, O'Brien JT, et al
    A spatial covariance 123I-5IA-85380 SPECT study of alpha4beta2 nicotinic receptors in Alzheimer's disease.
    Neurobiol Aging. 2016;47:83-90.
    PubMed     Text format     Abstract available


  53. GRATUZE M, Julien J, Morin F, Calon F, et al
    High-fat, high-sugar, and high-cholesterol consumption does not impact tau pathogenesis in a mouse model of Alzheimer's disease-like tau pathology.
    Neurobiol Aging. 2016;47:71-73.
    PubMed     Text format     Abstract available


  54. CAVANAGH C, Tse YC, Nguyen HB, Krantic S, et al
    Inhibiting tumor necrosis factor-alpha before amyloidosis prevents synaptic deficits in an Alzheimer's disease model.
    Neurobiol Aging. 2016;47:41-49.
    PubMed     Text format     Abstract available


  55. SMITH AR, Smith RG, Condliffe D, Hannon E, et al
    Increased DNA methylation near TREM2 is consistently seen in the superior temporal gyrus in Alzheimer's disease brain.
    Neurobiol Aging. 2016;47:35-40.
    PubMed     Text format     Abstract available


  56. HUANG L, Jin Y, Gao Y, Thung KH, et al
    Longitudinal clinical score prediction in Alzheimer's disease with soft-split sparse regression based random forest.
    Neurobiol Aging. 2016;46:180-191.
    PubMed     Text format     Abstract available


  57. MEDURI G, Guillemeau K, Dounane O, Sazdovitch V, et al
    Caspase-cleaved Tau-D421 is colocalized with the immunophilin FKBP52 in the autophagy-endolysosomal system of Alzheimer's disease neurons.
    Neurobiol Aging. 2016;46:124-137.
    PubMed     Text format     Abstract available


  58. RIVERA DS, Lindsay C, Codocedo JF, Morel I, et al
    Andrographolide recovers cognitive impairment in a natural model of Alzheimer's disease (Octodon degus).
    Neurobiol Aging. 2016;46:204-220.
    PubMed     Text format     Abstract available


  59. BRAS J, Djaldetti R, Alves AM, Mead S, et al
    Exome sequencing in a consanguineous family clinically diagnosed with early-onset Alzheimer's disease identifies a homozygous CTSF mutation.
    Neurobiol Aging. 2016 Jul 4. pii: S0197-4580(16)30118.
    PubMed     Text format     Abstract available


  60. BARZEGARAN E, van Damme B, Meuli R, Knyazeva MG, et al
    Perception-related EEG is more sensitive to Alzheimer's disease effects than resting EEG.
    Neurobiol Aging. 2016;43:129-39.
    PubMed     Text format     Abstract available


  61. STEKETEE RM, Meijboom R, de Groot M, Bron EE, et al
    Concurrent white and gray matter degeneration of disease-specific networks in early-stage Alzheimer's disease and behavioral variant frontotemporal dementia.
    Neurobiol Aging. 2016;43:119-28.
    PubMed     Text format     Abstract available


  62. COUTTAS TA, Kain N, Suchowerska AK, Quek LE, et al
    Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease.
    Neurobiol Aging. 2016;43:89-100.
    PubMed     Text format     Abstract available


  63. VANDAL M, White PJ, Tournissac M, Tremblay C, et al
    Impaired thermoregulation and beneficial effects of thermoneutrality in the 3xTg-AD model of Alzheimer's disease.
    Neurobiol Aging. 2016;43:47-57.
    PubMed     Text format     Abstract available


  64. HASSENSTAB J, Chasse R, Grabow P, Benzinger TL, et al
    Certified normal: Alzheimer's disease biomarkers and normative estimates of cognitive functioning.
    Neurobiol Aging. 2016;43:23-33.
    PubMed     Text format     Abstract available


  65. CIAVARDELLI D, Piras F, Consalvo A, Rossi C, et al
    Medium-chain plasma acylcarnitines, ketone levels, cognition, and gray matter volumes in healthy elderly, mildly cognitively impaired, or Alzheimer's disease subjects.
    Neurobiol Aging. 2016;43:1-12.
    PubMed     Text format     Abstract available


    June 2016
  66. DIAS C, Lourenco CF, Ferreiro E, Barbosa RM, et al
    Age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic regulation.
    Neurobiol Aging. 2016;46:84-95.
    PubMed     Text format     Abstract available


  67. MCDONOUGH IM, Bischof GN, Kennedy KM, Rodrigue KM, et al
    Discrepancies between fluid and crystallized ability in healthy adults: a behavioral marker of preclinical Alzheimer's disease.
    Neurobiol Aging. 2016;46:68-75.
    PubMed     Text format     Abstract available


  68. VAN DE HAAR HJ, Jansen JF, van Osch MJ, van Buchem MA, et al
    Neurovascular unit impairment in early Alzheimer's disease measured with magnetic resonance imaging.
    Neurobiol Aging. 2016;45:190-196.
    PubMed     Text format     Abstract available


  69. KNOPMAN DS, Jack CR Jr, Lundt ES, Weigand SD, et al
    Evolution of neurodegeneration-imaging biomarkers from clinically normal to dementia in the Alzheimer disease spectrum.
    Neurobiol Aging. 2016;46:32-42.
    PubMed     Text format     Abstract available


  70. BIEMANS EA, Verhoeven-Duif NM, Gerrits J, Claassen JA, et al
    CSF d-serine concentrations are similar in Alzheimer's disease, other dementias, and elderly controls.
    Neurobiol Aging. 2016;42:213-6.
    PubMed     Text format     Abstract available


  71. RIECKMANN A, Van Dijk KR, Sperling RA, Johnson KA, et al
    Accelerated decline in white matter integrity in clinically normal individuals at risk for Alzheimer's disease.
    Neurobiol Aging. 2016;42:177-88.
    PubMed     Text format     Abstract available


  72. YU M, Gouw AA, Hillebrand A, Tijms BM, et al
    Different functional connectivity and network topology in behavioral variant of frontotemporal dementia and Alzheimer's disease: an EEG study.
    Neurobiol Aging. 2016;42:150-62.
    PubMed     Text format     Abstract available


  73. TIERNAN CT, Ginsberg SD, Guillozet-Bongaarts AL, Ward SM, et al
    Protein homeostasis gene dysregulation in pretangle-bearing nucleus basalis neurons during the progression of Alzheimer's disease.
    Neurobiol Aging. 2016;42:80-90.
    PubMed     Text format     Abstract available


  74. ZHAO L, Mao Z, Woody SK, Brinton RD, et al
    Sex differences in metabolic aging of the brain: insights into female susceptibility to Alzheimer's disease.
    Neurobiol Aging. 2016;42:69-79.
    PubMed     Text format     Abstract available


  75. SOTO I, Grabowska WA, Onos KD, Graham LC, et al
    Meox2 haploinsufficiency increases neuronal cell loss in a mouse model of Alzheimer's disease.
    Neurobiol Aging. 2016;42:50-60.
    PubMed     Text format     Abstract available


  76. SCHEFF SW, Ansari MA, Mufson EJ
    Oxidative stress and hippocampal synaptic protein levels in elderly cognitively intact individuals with Alzheimer's disease pathology.
    Neurobiol Aging. 2016;42:1-12.
    PubMed     Text format     Abstract available


    May 2016
  77. PHIPPS AJ, Vickers JC, Taberlay PC, Woodhouse A, et al
    Neurofilament-labeled pyramidal neurons and astrocytes are deficient in DNA methylation marks in Alzheimer's disease.
    Neurobiol Aging. 2016;45:30-42.
    PubMed     Text format     Abstract available


  78. DAUWAN M, van Dellen E, van Boxtel L, van Straaten EC, et al
    EEG-directed connectivity from posterior brain regions is decreased in dementia with Lewy bodies: a comparison with Alzheimer's disease and controls.
    Neurobiol Aging. 2016;41:122-9.
    PubMed     Text format     Abstract available


  79. MEZ J, Mukherjee S, Thornton T, Fardo DW, et al
    The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable.
    Neurobiol Aging. 2016;41:115-21.
    PubMed     Text format     Abstract available


  80. YANG W, Zhou X, Zimmermann HR, Cavener DR, et al
    Repression of the eIF2alpha kinase PERK alleviates mGluR-LTD impairments in a mouse model of Alzheimer's disease.
    Neurobiol Aging. 2016;41:19-24.
    PubMed     Text format     Abstract available


  81. MORENO-CASTILLA P, Rodriguez-Duran LF, Guzman-Ramos K, Barcenas-Femat A, et al
    Dopaminergic neurotransmission dysfunction induced by amyloid-beta transforms cortical long-term potentiation into long-term depression and produces memory impairment.
    Neurobiol Aging. 2016;41:187-99.
    PubMed     Text format     Abstract available


  82. ANDREWS SJ, Das D, Cherbuin N, Anstey KJ, et al
    Association of genetic risk factors with cognitive decline: the PATH through life project.
    Neurobiol Aging. 2016;41:150-8.
    PubMed     Text format     Abstract available


  83. BRANGER P, Arenaza-Urquijo EM, Tomadesso C, Mezenge F, et al
    Relationships between sleep quality and brain volume, metabolism, and amyloid deposition in late adulthood.
    Neurobiol Aging. 2016;41:107-14.
    PubMed     Text format     Abstract available


  84. OTT S, Vishnivetskaya A, Malmendal A, Crowther DC, et al
    Metabolic changes may precede proteostatic dysfunction in a Drosophila model of amyloid beta peptide toxicity.
    Neurobiol Aging. 2016;41:39-52.
    PubMed     Text format     Abstract available


  85. SUNDERMANN EE, Wang C, Katz M, Zimmerman ME, et al
    Cholesteryl ester transfer protein genotype modifies the effect of apolipoprotein epsilon4 on memory decline in older adults.
    Neurobiol Aging. 2016;41:200.
    PubMed     Text format     Abstract available


    April 2016
  86. SASSI C, Nalls MA, Ridge PG, Gibbs JR, et al
    ABCA7 p.G215S as potential protective factor for Alzheimer's disease.
    Neurobiol Aging. 2016 Apr 20. pii: S0197-4580(16)30031.
    PubMed     Text format     Abstract available


  87. RETTBERG JR, Dang H, Hodis HN, Henderson VW, et al
    Identifying postmenopausal women at risk for cognitive decline within a healthy cohort using a panel of clinical metabolic indicators: potential for detecting an at-Alzheimer's risk metabolic phenotype.
    Neurobiol Aging. 2016;40:155-63.
    PubMed     Text format     Abstract available


  88. LIGUORI C, Nuccetelli M, Izzi F, Sancesario G, et al
    Rapid eye movement sleep disruption and sleep fragmentation are associated with increased orexin-A cerebrospinal-fluid levels in mild cognitive impairment due to Alzheimer's disease.
    Neurobiol Aging. 2016;40:120-6.
    PubMed     Text format     Abstract available


  89. DELLI PIZZI S, Franciotti R, Bubbico G, Thomas A, et al
    Atrophy of hippocampal subfields and adjacent extrahippocampal structures in dementia with Lewy bodies and Alzheimer's disease.
    Neurobiol Aging. 2016;40:103-9.
    PubMed     Text format     Abstract available


  90. LUPTON MK, Strike L, Hansell NK, Wen W, et al
    The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume.
    Neurobiol Aging. 2016;40:68-77.
    PubMed     Text format     Abstract available


  91. PUIG KL, Kulas JA, Franklin W, Rakoczy SG, et al
    The Ames dwarf mutation attenuates Alzheimer's disease phenotype of APP/PS1 mice.
    Neurobiol Aging. 2016;40:22-40.
    PubMed     Text format     Abstract available


  92. FLETCHER E, Villeneuve S, Maillard P, Harvey D, et al
    beta-amyloid, hippocampal atrophy and their relation to longitudinal brain change in cognitively normal individuals.
    Neurobiol Aging. 2016;40:173-80.
    PubMed     Text format     Abstract available


  93. XIANG PY, Janc O, Grochowska KM, Kreutz MR, et al
    Dopamine agonists rescue Abeta-induced LTP impairment by Src-family tyrosine kinases.
    Neurobiol Aging. 2016;40:98-102.
    PubMed     Text format     Abstract available


  94. VERDURAND M, Chauveau F, Daoust A, Morel AL, et al
    Differential effects of amyloid-beta 1-40 and 1-42 fibrils on 5-HT1A serotonin receptors in rat brain.
    Neurobiol Aging. 2016;40:11-21.
    PubMed     Text format     Abstract available


    March 2016
  95. GHANI M, Sato C, Kakhki EG, Gibbs JR, et al
    Mutation analysis of the MS4A and TREM gene clusters in a case-control Alzheimer's disease data set.
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    August 2015
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    June 2015
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  189. KATSOURI L, Ashraf A, Birch AM, Lee KK, et al
    Systemic administration of fibroblast growth factor-2 (FGF2) reduces BACE1 expression and amyloid pathology in APP23 mice.
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  190. FENG J, Meng C, Xing D
    Abeta induces PUMA activation: a new mechanism for Abeta-mediated neuronal apoptosis.
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    N-terminal region of myelin basic protein reduces fibrillar amyloid-beta deposition in Tg-5xFAD mice.
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    Modulation of AD neuropathology and memory impairments by the isoprostane F2alpha is mediated by the thromboxane receptor.
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    Greater cortical thinning in normal older adults predicts later cognitive impairment.
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    Task-evoked fMRI changes in attention networks are associated with preclinical Alzheimer's disease biomarkers.
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  198. BRAAE A, Medway C, Carrasquillo M, Younkin S, et al
    Blood type gene locus has no influence on ACE association with Alzheimer's disease.
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  200. MAK E, Su L, Williams GB, Watson R, et al
    Progressive cortical thinning and subcortical atrophy in dementia with Lewy bodies and Alzheimer's disease.
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  201. JENSEN MM, Arvaniti M, Mikkelsen JD, Michalski D, et al
    Prostate stem cell antigen interacts with nicotinic acetylcholine receptors and is affected in Alzheimer's disease.
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  202. CHAUHAN G, Adams HH, Bis JC, Weinstein G, et al
    Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.
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  203. TURANO E, Busetto G, Marconi S, Guzzo F, et al
    Neurotoxicity and synaptic plasticity impairment of N-acetylglucosamine polymers: implications for Alzheimer's disease.
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  204. NIR TM, Jahanshad N, Toga AW, Bernstein MA, et al
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  205. RAAMANA PR, Weiner MW, Wang L, Beg MF, et al
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  206. CHING CR, Hua X, Hibar DP, Ward CP, et al
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  209. MADSEN SK, Gutman BA, Joshi SH, Toga AW, et al
    Mapping ventricular expansion onto cortical gray matter in older adults.
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  210. KHAN AR, Wang L, Beg MF
    Unified voxel- and tensor-based morphometry (UVTBM) using registration confidence.
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  211. PRADOS F, Cardoso MJ, Leung KK, Cash DM, et al
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    December 2014
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    L-type calcium channel blockers and substance P induce angiogenesis of cortical vessels associated with beta-amyloid plaques in an Alzheimer mouse model.
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  216. PIETRZAK RH, Lim YY, Ames D, Harrington K, et al
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    Neural stem cell transplantation enhances mitochondrial biogenesis in a transgenic mouse model of Alzheimer's disease-like pathology.
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  218. JIANG HY, Li GD, Dai SX, Bi R, et al
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  220. PETERS C, Espinoza MP, Gallegos S, Opazo C, et al
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  221. TIMMER NM, Herbert MK, Claassen JA, Kuiperij HB, et al
    Total glutamine synthetase levels in cerebrospinal fluid of Alzheimer's disease patients are unchanged.
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  222. LIM YY, Villemagne VL, Pietrzak RH, Ames D, et al
    APOE epsilon4 moderates amyloid-related memory decline in preclinical Alzheimer's disease.
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  223. LOUWERSHEIMER E, Ramirez A, Cruchaga C, Becker T, et al
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  224. KO C, Chu Y, Narumiya S, Chi J, et al
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    October 2014
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    Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type.
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    Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration.
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  227. FINCH CE, Austad SN
    Commentary: is Alzheimer's disease uniquely human?
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  228. BI R, Zhang W, Yu D, Li X, et al
    Mitochondrial DNA haplogroup B5 confers genetic susceptibility to Alzheimer's disease in Han Chinese.
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  229. JEDYNAK BM, Liu B, Lang A, Gel Y, et al
    A computational method for computing an Alzheimer's disease progression score; experiments and validation with the ADNI data set.
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  230. HASSAN WM, Dostal V, Huemann BN, Yerg JE, et al
    Identifying Abeta-specific pathogenic mechanisms using a nematode model of Alzheimer's disease.
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  231. JIANG X, Chai GS, Wang ZH, Hu Y, et al
    CaMKII-dependent dendrite ramification and spine generation promote spatial training-induced memory improvement in a rat model of sporadic Alzheimer's disease.
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  232. SERRA L, Musicco M, Cercignani M, Torso M, et al
    Cognitive reserve and the risk for Alzheimer's disease: a longitudinal study.
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    gamma-Hydroxybutyrate (Xyrem) ameliorates clinical symptoms and neuropathology in a mouse model of Alzheimer's disease.
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    Advanced glycation end products are mitogenic signals and trigger cell cycle reentry of neurons in Alzheimer's disease brain.
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  235. MING J, Harms MP, Morris JC, Beg MF, et al
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    Association of CD33 polymorphism rs3865444 with Alzheimer's disease pathology and CD33 expression in human cerebral cortex.
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    September 2014
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    The storm before the quiet: neuronal hyperactivity and Abeta in the presymptomatic stages of Alzheimer's disease.
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  239. SCHMOLE AC, Lundt R, Ternes S, Albayram O, et al
    Cannabinoid receptor 2 deficiency results in reduced neuroinflammation in an Alzheimer's disease mouse model.
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  240. MURPHY M, Wilson YM, Vargas E, Munro KM, et al
    Reduction of p75 neurotrophin receptor ameliorates the cognitive deficits in a model of Alzheimer's disease.
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  241. BABILONI C, Del Percio C, Boccardi M, Lizio R, et al
    Occipital sources of resting-state alpha rhythms are related to local gray matter density in subjects with amnesic mild cognitive impairment and Alzheimer's disease.
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  242. MORRIS MC, Tangney CC
    Dietary fat composition and dementia risk.
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    Nutrition and the brain: what advice should we give?
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  244. BARNARD ND, Bunner AE, Agarwal U
    Saturated and trans fats and dementia: a systematic review.
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    Calcium regulates the interaction of amyloid precursor protein with Homer3 protein.
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  248. HAN P, Tang Z, Yin J, Maalouf M, et al
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    August 2014
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    Higher homocysteine associated with thinner cortical gray matter in 803 participants from the Alzheimer's Disease Neuroimaging Initiative.
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    Amygdalar atrophy in symptomatic Alzheimer's disease based on diffeomorphometry: the BIOCARD cohort.
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  254. DUCHESNE S, Valdivia F, Mouiha A, Robitaille N, et al
    Single time point high-dimensional morphometry in Alzheimer's disease: group statistics on longitudinally acquired data.
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    July 2014
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    June 2014
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    Age-associated dysregulation of microglial activation is coupled with enhanced blood-brain barrier permeability and pathology in APP/PS1 mice.
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    Age-related decline in white matter integrity in a mouse model of tauopathy: an in vivo diffusion tensor magnetic resonance imaging study.
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    Triggering receptor expressed on myeloid cells 2 knockdown exacerbates aging-related neuroinflammation and cognitive deficiency in senescence-accelerated mouse prone 8 mice.
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    Golgin-84-associated Golgi fragmentation triggers tau hyperphosphorylation by activation of cyclin-dependent kinase-5 and extracellular signal-regulated kinase.
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