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The Medical Article of the Year 2008:
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78.
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  Alzheimer's Disease

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Articles published in Neurobiol Dis

Retrieve available abstracts of 59 articles:
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Single Articles


    May 2008
  1. REYES JF , Reynolds MR, Horowitz PM, Fu Y, et al
    A possible link between astrocyte activation and tau nitration in Alzheimer's disease.
    Neurobiol Dis. 2008;.
    PubMed     Related articles    Abstract available


    April 2008
  2. LIU L , Orozco IJ, Planel E, Wen Y, et al
    A transgenic rat that develops Alzheimer's disease-like amyloid pathology, deficits in synaptic plasticity and cognitive impairment.
    Neurobiol Dis. 2008;.
    PubMed     Related articles    Abstract available


  3. PARACHIKOVA A , Nichol KE, Cotman CW
    Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition.
    Neurobiol Dis. 2008;30:121-9.
    PubMed     Related articles    Abstract available


    March 2008
  4. LEUBA G , Walzer C, Vernay A, Carnal B, et al
    Postsynaptic density protein PSD-95 expression in Alzheimer's disease and okadaic acid induced neuritic retraction.
    Neurobiol Dis. 2008;.
    PubMed     Related articles    Abstract available


    February 2008
  5. OBREGON D , Hou H, Bai Y, Nikolic WV, et al
    CD40L disruption enhances Abeta vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation.
    Neurobiol Dis. 2008;29:336-53.
    PubMed     Related articles    Abstract available


  6. CHEN Q , Nakajima A, Choi SH, Xiong X, et al
    Adult neurogenesis is functionally associated with AD-like neurodegeneration.
    Neurobiol Dis. 2008;29:316-26.
    PubMed     Related articles    Abstract available


  7. LOVELL MA , Markesbery WR
    Oxidatively modified RNA in mild cognitive impairment.
    Neurobiol Dis. 2008;29:169-75.
    PubMed     Related articles    Abstract available


    January 2008
  8. CHAPUIS J , Hannequin D, Pasquier F, Bentham P, et al
    Association study of the GAB2 gene with the risk of developing Alzheimer's disease.
    Neurobiol Dis. 2008;.
    PubMed     Related articles    Abstract available


  9. REED T , Perluigi M, Sultana R, Pierce WM, et al
    Redox proteomic identification of 4-Hydroxy-2-nonenal-modified brain proteins in amnestic mild cognitive impairment: Insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimer's disease.
    Neurobiol Dis. 2008;.
    PubMed     Related articles    Abstract available


    December 2007
  10. GARCIA-ALLOZA M , Ferrara BJ, Dodwell SA, Hickey GA, et al
    A limited role for microglia in antibody mediated plaque clearance in APP mice.
    Neurobiol Dis. 2007;28:286-92.
    PubMed     Related articles    Abstract available   Free Full Text


    November 2007
  11. BADER LANGE ML , Cenini G, Piroddi M, Mohmmad Abdul H, et al
    Loss of phospholipid asymmetry and elevated brain apoptotic protein levels in subjects with amnestic mild cognitive impairment and Alzheimer disease.
    Neurobiol Dis. 2007;.
    PubMed     Related articles    Abstract available


  12. XIONG H , Callaghan D, Jones A, Walker DG, et al
    Cholesterol retention in Alzheimer's brain is responsible for high beta- and gamma-secretase activities and Abeta production.
    Neurobiol Dis. 2007;.
    PubMed     Related articles    Abstract available


    October 2007
  13. DAMJANAC M , Rioux Bilan A, Paccalin M, Pontcharraud R, et al
    Dissociation of Akt/PKB and ribosomal S6 kinase signaling markers in a transgenic mouse model of Alzheimer's disease.
    Neurobiol Dis. 2007;.
    PubMed     Related articles    Abstract available


  14. PEREZ SE , Dar S, Ikonomovic MD, DeKosky ST, et al
    Cholinergic forebrain degeneration in the APPswe/PS1DeltaE9 transgenic mouse.
    Neurobiol Dis. 2007;28:3-15.
    PubMed     Related articles    Abstract available


  15. CLINTON LK , Billings LM, Green KN, Caccamo A, et al
    Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice.
    Neurobiol Dis. 2007;28:76-82.
    PubMed     Related articles    Abstract available


    September 2007
  16. LI Y , Rowland C, Catanese J, Morris J, et al
    SORL1 variants and risk of late-onset Alzheimer's disease.
    Neurobiol Dis. 2007;.
    PubMed     Related articles    Abstract available


  17. RYU JK , McLarnon JG
    Thalidomide inhibition of perturbed vasculature and glial-derived tumor necrosis factor-alpha in an animal model of inflamed Alzheimer's disease brain.
    Neurobiol Dis. 2007;.
    PubMed     Related articles    Abstract available


  18. MURPHY MP , Beckett TL, Ding Q, Patel E, et al
    Abeta solubility and deposition during AD progression and in APPxPS-1 knock-in mice.
    Neurobiol Dis. 2007;27:301-11.
    PubMed     Related articles    Abstract available


    August 2007
  19. GAN L , Qiao S, Lan X, Chi L, et al
    Neurogenic responses to amyloid-beta plaques in the brain of Alzheimer's disease-like transgenic (pPDGF-APP(Sw,Ind)) mice.
    Neurobiol Dis. 2007;.
    PubMed     Related articles    Abstract available


  20. CACQUEVEL M , Launay S, Castel H, Benchenane K, et al
    Ageing and amyloid-beta peptide deposition contribute to an impaired brain tissue plasminogen activator activity by different mechanisms.
    Neurobiol Dis. 2007;27:164-73.
    PubMed     Related articles    Abstract available


    July 2007
  21. HONSON NS , Johnson RL, Huang W, Inglese J, et al
    Differentiating Alzheimer disease-associated aggregates with small molecules.
    Neurobiol Dis. 2007;.
    PubMed     Related articles    Abstract available


  22. PARACHIKOVA A , Cotman CW
    Reduced CXCL12/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease.
    Neurobiol Dis. 2007;.
    PubMed     Related articles    Abstract available


    June 2007
  23. HOOIJMANS CR , Rutters F, Dederen PJ, Gambarota G, et al
    Changes in cerebral blood volume and amyloid pathology in aged Alzheimer APP/PS1 mice on a docosahexaenoic acid (DHA) diet or cholesterol enriched Typical Western Diet (TWD).
    Neurobiol Dis. 2007;.
    PubMed     Related articles    Abstract available


  24. HUMBERT J , Beyer K, Carrato C, Mate JL, et al
    Parkin and synphilin-1 isoform expression changes in Lewy body diseases.
    Neurobiol Dis. 2007;26:681-7.
    PubMed     Related articles    Abstract available


  25. ESPOSITO A , Dohm CP, Kermer P, Bahr M, et al
    alpha-Synuclein and its disease-related mutants interact differentially with the microtubule protein tau and associate with the actin cytoskeleton.
    Neurobiol Dis. 2007;26:521-31.
    PubMed     Related articles    Abstract available


    May 2007
  26. SHIROTANI K , Tomioka M, Kremmer E, Haass C, et al
    Pathological activity of familial Alzheimer's disease-associated mutant presenilin can be executed by six different gamma-secretase complexes.
    Neurobiol Dis. 2007;.
    PubMed     Related articles    Abstract available


  27. CELSI F , Svedberg M, Unger C, Cotman CW, et al
    Beta-amyloid causes downregulation of calcineurin in neurons through induction of oxidative stress.
    Neurobiol Dis. 2007;26:342-52.
    PubMed     Related articles    Abstract available


    April 2007
  28. NIELSEN HM , Londos E, Minthon L, Janciauskiene SM, et al
    Soluble adhesion molecules and angiotensin-converting enzyme in dementia.
    Neurobiol Dis. 2007;26:27-35.
    PubMed     Related articles    Abstract available


    March 2007
  29. VINGTDEUX V , Hamdane M, Begard S, Loyens A, et al
    Intracellular pH regulates amyloid precursor protein intracellular domain accumulation.
    Neurobiol Dis. 2007;25:686-96.
    PubMed     Related articles    Abstract available


  30. MYERS AJ , Pittman AM, Zhao AS, Rohrer K, et al
    The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts.
    Neurobiol Dis. 2007;25:561-70.
    PubMed     Related articles    Abstract available


    February 2007
  31. BRIJBASSI S , Amtul Z, Newbigging S, Westaway D, et al
    Excess of nicastrin in brain results in heterozygosity having no effect on endogenous APP processing and amyloid peptide levels in vivo.
    Neurobiol Dis. 2007;25:291-6.
    PubMed     Related articles    Abstract available


    January 2007
  32. HEMMING ML , Selkoe DJ, Farris W
    Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid beta-protein metabolism in mouse models of Alzheimer disease.
    Neurobiol Dis. 2007;.
    PubMed     Related articles    Abstract available


  33. HALAGAPPA VK , Guo Z, Pearson M, Matsuoka Y, et al
    Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease.
    Neurobiol Dis. 2007;.
    PubMed     Related articles    Abstract available


  34. CHRISTIE LA , Su JH, Tu CH, Dick MC, et al
    Differential regulation of inhibitors of apoptosis proteins in Alzheimer's disease brains.
    Neurobiol Dis. 2007;.
    PubMed     Related articles    Abstract available


    December 2006
  35. PESARESI M , Batelli S, Prato F, Polito L, et al
    The urokinase-type plasminogen activator polymorphism PLAU_1 is a risk factor for APOE-epsilon4 non-carriers in the Italian Alzheimer's disease population and does not affect the plasma Abeta(1-42) level.
    Neurobiol Dis. 2006;.
    PubMed     Related articles    Abstract available


  36. POIRIER R , Wolfer DP, Welzl H, Tracy J, et al
    Neuronal neprilysin overexpression is associated with attenuation of Abeta-related spatial memory deficit.
    Neurobiol Dis. 2006;24:475-83.
    PubMed     Related articles    Abstract available


    November 2006
  37. KISHIKAWA S , Li JL, Gillis T, Hakky MM, et al
    Brain-derived neurotrophic factor does not influence age at neurologic onset of Huntington's disease.
    Neurobiol Dis. 2006;24:280-5.
    PubMed     Related articles    Abstract available


    October 2006
  38. GARCIA-ALLOZA M , Robbins EM, Zhang-Nunes SX, Purcell SM, et al
    Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease.
    Neurobiol Dis. 2006;.
    PubMed     Related articles    Abstract available


    September 2006
  39. HARTMAN RE , Shah A, Fagan AM, Schwetye KE, et al
    Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2006;.
    PubMed     Related articles    Abstract available


  40. DARREH-SHORI T , Brimijoin S, Kadir A, Almkvist O, et al
    Differential CSF butyrylcholinesterase levels in Alzheimer's disease patients with the ApoE epsilon4 allele, in relation to cognitive function and cerebral glucose metabolism.
    Neurobiol Dis. 2006;.
    PubMed     Related articles    Abstract available


  41. FERREIRO E , Resende R, Costa R, Oliveira CR, et al
    An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity.
    Neurobiol Dis. 2006;23:669-78.
    PubMed     Related articles    Abstract available


  42. VAN GROEN T , Kiliaan AJ, Kadish I
    Deposition of mouse amyloid beta in human APP/PS1 double and single AD model transgenic mice.
    Neurobiol Dis. 2006;23:653-62.
    PubMed     Related articles    Abstract available


  43. SCHNEIDER A , Schulz-Schaeffer W, Hartmann T, Schulz JB, et al
    Cholesterol depletion reduces aggregation of amyloid-beta peptide in hippocampal neurons.
    Neurobiol Dis. 2006;23:573-7.
    PubMed     Related articles    Abstract available


  44. OKSMAN M , Iivonen H, Hogyes E, Amtul Z, et al
    Impact of different saturated fatty acid, polyunsaturated fatty acid and cholesterol containing diets on beta-amyloid accumulation in APP/PS1 transgenic mice.
    Neurobiol Dis. 2006;23:563-72.
    PubMed     Related articles    Abstract available


    August 2006
  45. BURGESS BL , McIsaac SA, Naus KE, Chan JY, et al
    Elevated plasma triglyceride levels precede amyloid deposition in Alzheimer's disease mouse models with abundant Abeta in plasma.
    Neurobiol Dis. 2006;.
    PubMed     Related articles    Abstract available


  46. MAES OC , Kravitz S, Mawal Y, Su H, et al
    Characterization of alpha(1)-antitrypsin as a heme oxygenase-1 suppressor in Alzheimer plasma.
    Neurobiol Dis. 2006;.
    PubMed     Related articles    Abstract available


  47. BELLUCCI A , Luccarini I, Scali C, Prosperi C, et al
    Cholinergic dysfunction, neuronal damage and axonal loss in TgCRND8 mice.
    Neurobiol Dis. 2006;23:260-72.
    PubMed     Related articles    Abstract available


    June 2006
  48. BOEKHOORN K , Joels M, Lucassen PJ
    Increased proliferation reflects glial and vascular-associated changes, but not neurogenesis in the presenile Alzheimer hippocampus.
    Neurobiol Dis. 2006;.
    PubMed     Related articles    Abstract available


  49. FUKUCHI KI , Tahara K, Kim HD, Maxwell JA, et al
    Anti-Abeta single-chain antibody delivery via adeno-associated virus for treatment of Alzheimer's disease.
    Neurobiol Dis. 2006;.
    PubMed     Related articles    Abstract available


  50. HERSKOVITS AZ , Davies P
    The regulation of tau phosphorylation by PCTAIRE 3: Implications for the pathogenesis of Alzheimer's disease.
    Neurobiol Dis. 2006;.
    PubMed     Related articles    Abstract available


  51. GOTTI C , Moretti M, Bohr I, Ziabreva I, et al
    Selective nicotinic acetylcholine receptor subunit deficits identified in Alzheimer's disease, Parkinson's disease and dementia with Lewy bodies by immunoprecipitation.
    Neurobiol Dis. 2006;.
    PubMed     Related articles    Abstract available


    May 2006
  52. ETHELL DW , Shippy D, Cao C, Cracchiolo JR, et al
    Abeta-specific T-cells reverse cognitive decline and synaptic loss in Alzheimer's mice.
    Neurobiol Dis. 2006;.
    PubMed     Related articles    Abstract available


  53. YOON SY , Choi JE, Yoon JH, Huh JW, et al
    BACE inhibitor reduces APP-beta-C-terminal fragment accumulation in axonal swellings of okadaic acid-induced neurodegeneration.
    Neurobiol Dis. 2006;22:435-44.
    PubMed     Related articles    Abstract available


  54. BARRACHINA M , Castano E, Dalfo E, Maes T, et al
    Reduced ubiquitin C-terminal hydrolase-1 expression levels in dementia with Lewy bodies.
    Neurobiol Dis. 2006;22:265-73.
    PubMed     Related articles    Abstract available


    April 2006
  55. KULIC L , Kurosinski P, Chen F, Tracy J, et al
    Active immunization trial in Abeta42-injected P301L tau transgenic mice.
    Neurobiol Dis. 2006;22:50-6.
    PubMed     Related articles    Abstract available


  56. LEE KW , Im JY, Song JS, Lee SH, et al
    Progressive neuronal loss and behavioral impairments of transgenic C57BL/6 inbred mice expressing the carboxy terminus of amyloid precursor protein.
    Neurobiol Dis. 2006;22:10-24.
    PubMed     Related articles    Abstract available


    March 2006
  57. LUPIEN SB , Bluhm EJ, Ishii DN
    Effect of IGF-I on DNA, RNA, and protein loss associated with brain atrophy and impaired learning in diabetic rats.
    Neurobiol Dis. 2006;21:487-95.
    PubMed     Related articles    Abstract available


  58. BLAIN JF , Sullivan PM, Poirier J
    A deficit in astroglial organization causes the impaired reactive sprouting in human apolipoprotein E4 targeted replacement mice.
    Neurobiol Dis. 2006;21:505-14.
    PubMed     Related articles    Abstract available


    February 2006
  59. DING X , MacTavish D, Kar S, Jhamandas JH, et al
    Galanin attenuates beta-amyloid (Abeta) toxicity in rat cholinergic basal forebrain neurons.
    Neurobiol Dis. 2006;21:413-20.
    PubMed     Related articles    Abstract available


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