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  Anemia

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Articles published in Blood

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    November 2017
  1. GARCIA-SANTOS D, Hamdi A, Saxova Z, Fillebeen C, et al
    Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in beta-thalassemia mouse model.
    Blood. 2017 Nov 27. pii: blood-2017-07-798728. doi: 10.1182/blood-2017-07-798728
    PubMed     Text format     Abstract available


  2. STAUDER R, Valent P, Theurl I
    Anemia at older age: etiologies, clinical implications and management.
    Blood. 2017 Nov 15. pii: blood-2017-07-746446. doi: 10.1182/blood-2017-07-746446
    PubMed     Text format     Abstract available


  3. KORDBACHEH F, O'Meara CH, Coupland LA, Lelliott PM, et al
    Extracellular histones induce erythrocyte fragility and anemia.
    Blood. 2017 Nov 13. pii: blood-2017-06-790519. doi: 10.1182/blood-2017-06-790519
    PubMed     Text format     Abstract available


  4. MEINDERTS SM, Sins JWR, Fijnvandraat K, Nagelkerke SQ, et al
    Nonclassical FCGR2C haplotype is associated with protection from red blood cell alloimmunization in sickle cell disease.
    Blood. 2017;130:2121-2130.
    PubMed     Text format     Abstract available


  5. MORIKIS VA, Chase S, Wun T, Chaikof EL, et al
    Selectin catch-bonds mechanotransduce integrin activation and neutrophil arrest on inflamed endothelium under shear flow.
    Blood. 2017;130:2101-2110.
    PubMed     Text format     Abstract available


  6. VON WNUCK LIPINSKI K, Weske S, Keul P, Peters S, et al
    Hepatocyte nuclear factor 1A deficiency causes hemolytic anemia in mice by altering erythrocyte sphingolipid homeostasis.
    Blood. 2017 Nov 6. pii: blood-2017-03-774356. doi: 10.1182/blood-2017-03-774356.
    PubMed     Text format     Abstract available


    October 2017
  7. FITZHUGH CD, Cordes S, Taylor T, Coles W, et al
    At least 20% donor myeloid chimerism is necessary to reverse the sickle phenotype after allogeneic HSCT.
    Blood. 2017;130:1946-1948.
    PubMed     Text format     Abstract available


  8. OPOKA RO, Ndugwa CM, Latham TS, Lane A, et al
    Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia.
    Blood. 2017 Oct 19. pii: blood-2017-06-788935. doi: 10.1182/blood-2017-06-788935
    PubMed     Text format     Abstract available


  9. BYRNES JR, Wolberg AS
    Red blood cells in thrombosis.
    Blood. 2017;130:1795-1799.
    PubMed     Text format     Abstract available


  10. GLOGOWSKA E, Schneider ER, Maksimova Y, Schulz VP, et al
    Novel mechanisms of PIEZO1 dysfunction in hereditary xerocytosis.
    Blood. 2017;130:1845-1856.
    PubMed     Text format     Abstract available


  11. WAYNE AS, Shah NN, Bhojwani D, Silverman LB, et al
    Phase 1 study of the anti-CD22 immunotoxin moxetumomab pasudotox for childhood acute lymphoblastic leukemia.
    Blood. 2017;130:1620-1627.
    PubMed     Text format     Abstract available


    September 2017
  12. BERTHAUT I, Bachir D, Kotti S, Chalas C, et al
    Adverse effect of hydroxyurea on spermatogenesis in patients with sickle cell anemia after six months of treatment.
    Blood. 2017 Sep 28. pii: blood-2017-03-771857. doi: 10.1182/blood-2017-03-771857
    PubMed     Text format    


  13. DUBERT M, Elion J, Tolo A, Diallo DA, et al
    Degree of Anemia, Indirect Markers of Hemolysis, and Vascular Complications of Sickle Cell Disease in Africa.
    Blood. 2017 Sep 20. pii: blood-2016-12-755777. doi: 10.1182/blood-2016-12-755777
    PubMed     Text format     Abstract available


  14. KUNG C, Hixon J, Kosinski PA, Cianchetta G, et al
    AG-348 enhances pyruvate kinase activity in red blood cells from patients with pyruvate kinase deficiency.
    Blood. 2017;130:1347-1356.
    PubMed     Text format     Abstract available


  15. NEGORO E, Nagata Y, Clemente MJ, Hosono N, et al
    Origins of myelodysplastic syndromes after aplastic anemia.
    Blood. 2017 Sep 11. pii: blood-2017-02-767731. doi: 10.1182/blood-2017-02-767731
    PubMed     Text format    


  16. CARSON JL, Stanworth SJ
    Anemia and bleeding in thrombocytopenic patients.
    Blood. 2017;130:1178-1179.
    PubMed     Text format    


  17. GANZ T, Jung G, Naeim A, Ginzburg Y, et al
    Immunoassay for human serum erythroferrone.
    Blood. 2017;130:1243-1246.
    PubMed     Text format     Abstract available


    August 2017

  18. Zaimoku Y, Takamatsu H, Hosomichi K, et al. Identification of an HLA class I allele closely involved in the autoantigen presentation in acquired aplastic anemia. Blood. 2017;129(21):2908-2916.
    Blood. 2017;130:1072.
    PubMed     Text format    


  19. RIO P, Navarro S, Guenechea G, Sanchez-Dominguez R, et al
    Engraftment and in vivo proliferation advantage of gene corrected mobilized CD34+ cells from Fanconi anemia patients.
    Blood. 2017 Aug 11. pii: blood-2017-03-774174. doi: 10.1182/blood-2017-03-774174
    PubMed     Text format     Abstract available


    July 2017
  20. WAGNER-BALLON O, Michel M
    A rare case of autoimmune hemolytic anemia.
    Blood. 2017;130:559.
    PubMed     Text format    


  21. BERENTSEN S, Randen U, Oksman M, Birgens H, et al
    Bendamustine plus rituximab for chronic cold agglutinin disease: results of a Nordic prospective multicenter trial.
    Blood. 2017;130:537-541.
    PubMed     Text format     Abstract available


  22. KELLY AM, Garner SF, Foukaneli T, Godec TR, et al
    The effect of variation in donor platelet function on transfusion outcome: a semirandomized controlled trial.
    Blood. 2017;130:214-220.
    PubMed     Text format     Abstract available


  23. GORDEUK VR
    Hemochromatosis, iron-loading anemia, and SMAD.
    Blood. 2017;130:6-7.
    PubMed     Text format    


    June 2017
  24. MALCOVATI L, Galli A, Travaglino E, Ambaglio I, et al
    Clinical significance of somatic mutation in unexplained blood cytopenia.
    Blood. 2017;129:3371-3378.
    PubMed     Text format     Abstract available


  25. ULIRSCH JC, Lareau C, Ludwig LS, Mohandas N, et al
    Confounding in ex vivo models of Diamond-Blackfan anemia.
    Blood. 2017 Jun 14. pii: blood-2017-05-783191. doi: 10.1182/blood-2017-05-783191
    PubMed     Text format    


  26. SIWAPONANAN P, Siegers JY, Ghazali R, Ng T, et al
    Reduced PU.1 expression underlies aberrant neutrophil maturation and function in beta-thalassemia mice and patients.
    Blood. 2017;129:3087-3099.
    PubMed     Text format     Abstract available


  27. CHATURVEDI S, Bhatnagar P, Bean CJ, Steinberg MH, et al
    Genome-wide association study to identify variants associated with vaso-occlusive pain in sickle cell anemia.
    Blood. 2017 Jun 5. pii: blood-2017-02-769661. doi: 10.1182/blood-2017-02-769661.
    PubMed     Text format    


  28. DESAI AA, Lei Z, Bahroos N, Maienschein-Cline M, et al
    Association of circulating transcriptomic profiles with mortality in sickle cell disease.
    Blood. 2017;129:3009-3016.
    PubMed     Text format     Abstract available


  29. E S, Seth A, Vogel P, Sommers M, et al
    Bidirectional immune tolerance in nonmyeloablative MHC-mismatched BMT for murine beta-thalassemia.
    Blood. 2017;129:3017-3030.
    PubMed     Text format     Abstract available


    May 2017
  30. MASIAS C, Vasu S, Cataland SR
    None of the above: thrombotic microangiopathy beyond TTP and HUS.
    Blood. 2017;129:2857-2863.
    PubMed     Text format     Abstract available


  31. JOKIRANTA TS
    HUS and atypical HUS.
    Blood. 2017;129:2847-2856.
    PubMed     Text format     Abstract available


  32. EATON WA, Bunn HF
    Treating sickle cell disease by targeting HbS polymerization.
    Blood. 2017;129:2719-2726.
    PubMed     Text format     Abstract available


  33. NISS O, Fleck R, Makue F, Alsaied T, et al
    Association between diffuse myocardial fibrosis and diastolic dysfunction in sickle cell anemia.
    Blood. 2017 May 15. pii: blood-2017-02-767624. doi: 10.1182/blood-2017-02-767624
    PubMed     Text format     Abstract available


  34. FALCON CP, Howard TH
    An infant with Pearson syndrome: a rare cause of congenital sideroblastic anemia and bone marrow failure.
    Blood. 2017;129:2710.
    PubMed     Text format    


  35. GREEN R
    Vitamin B12 deficiency from the perspective of a practicing hematologist.
    Blood. 2017;129:2603-2611.
    PubMed     Text format     Abstract available


  36. KURUVILLA J, Savona M, Baz R, Mau-Sorensen M, et al
    Selective inhibition of nuclear export with selinexor in patients with non-Hodgkin's lymphoma.
    Blood. 2017 May 3. pii: blood-2016-11-750174. doi: 10.1182/blood-2016-11-750174.
    PubMed     Text format     Abstract available


    April 2017
  37. WANG CY, Core AB, Canali S, Zumbrennen-Bullough KB, et al
    Smad1/5 is required for erythropoietin-mediated suppression of hepcidin in mice.
    Blood. 2017 Apr 24. pii: blood-2016-12-759423. doi: 10.1182/blood-2016-12-759423
    PubMed     Text format     Abstract available


  38. CRISPINO JD, Horwitz MS
    GATA factor mutations in hematologic disease.
    Blood. 2017;129:2103-2110.
    PubMed     Text format     Abstract available


  39. CORAT MA, Schlums H, Wu C, Theorell J, et al
    Acquired somatic mutations in PNH reveal long-term maintenance of adaptive NK cells independent of HSPCs.
    Blood. 2017;129:1940-1946.
    PubMed     Text format     Abstract available


  40. O'BRIEN KA, Farrar JE, Vlachos A, Anderson SM, et al
    Molecular convergence in ex vivo models of Diamond Blackfan anemia.
    Blood. 2017 Apr 4. pii: blood-2017-01-760462. doi: 10.1182/blood-2017-01-760462.
    PubMed     Text format     Abstract available


    March 2017
  41. GO RS, Winters JL, Kay NE
    How I treat autoimmune hemolytic anemia.
    Blood. 2017 Mar 30. pii: blood-2016-11-693689. doi: 10.1182/blood-2016-11-693689
    PubMed     Text format     Abstract available


  42. SONGDEJ D, Babbs C, Higgs DR
    An international registry of survivors with Hb Bart's hydrops fetalis syndrome.
    Blood. 2017;129:1251-1259.
    PubMed     Text format     Abstract available


  43. UEDA Y, Mohammed I, Song D, Gullipalli D, et al
    Murine systemic thrombophilia and hemolytic uremic syndrome from a factor H point mutation.
    Blood. 2017;129:1184-1196.
    PubMed     Text format     Abstract available


    February 2017
  44. LI G, Hilliard LM
    Morphologic features of normoblasts in a case of myopathy, lactic acidosis, and sideroblastic anemia.
    Blood. 2017;129:1057.
    PubMed     Text format    


  45. ZAIMOKU Y, Takamatsu H, Hosomichi K, Ozawa T, et al
    Identification of an HLA class I allele closely involved in the auto-antigen presentation in acquired aplastic anemia.
    Blood. 2017 Feb 23. pii: blood-2016-11-752378. doi: 10.1182/blood-2016-11-752378
    PubMed     Text format     Abstract available


  46. HARDER MJ, Kuhn N, Schrezenmeier H, Hochsmann B, et al
    Incomplete inhibition by eculizumab: mechanistic evidence for residual C5 activity during strong complement activation.
    Blood. 2017;129:970-980.
    PubMed     Text format     Abstract available


  47. ASSHOFF M, Petzer V, Warr MR, Haschka D, et al
    Momelotinib inhibits ACVR1/ALK2, decreases hepcidin production and ameliorates anemia of chronic disease in rodents.
    Blood. 2017 Feb 10. pii: blood-2016-09-740092. doi: 10.1182/blood-2016-09-740092
    PubMed     Text format     Abstract available


  48. JOSEFSDOTTIR KS, Baldridge MT, Kadmon CS, King KY, et al
    Antibiotics impair murine hematopoiesis by depleting the intestinal microbiota.
    Blood. 2017;129:729-739.
    PubMed     Text format     Abstract available


  49. MEHTA PA, Davies SM, Leemhuis T, Myers K, et al
    Radiation-free, alternative donor HCT for Fanconi anemia patients: results from a prospective multi-institutional study.
    Blood. 2017 Feb 8. pii: blood-2016-09-743112. doi: 10.1182/blood-2016-09-743112.
    PubMed     Text format     Abstract available


  50. NOY A, de Vos S, Thieblemont C, Martin P, et al
    Targeting BTK with ibrutinib in relapsed/refractory marginal zone lymphoma.
    Blood. 2017 Feb 6. pii: blood-2016-10-747345. doi: 10.1182/blood-2016-10-747345.
    PubMed     Text format     Abstract available


  51. LI H, Choesang T, Bao W, Chen H, et al
    Decreasing TfR1 expression reverses anemia and hepcidin suppression in beta-thalassemic mice.
    Blood. 2017 Feb 1. pii: blood-2016-09-742387. doi: 10.1182/blood-2016-09-742387.
    PubMed     Text format     Abstract available


    January 2017
  52. BACIGALUPO A
    How I treat acquired aplastic anemia.
    Blood. 2017 Jan 17. pii: blood-2016-08-693481. doi: 10.1182/blood-2016-08-693481
    PubMed     Text format     Abstract available


    December 2016
  53. ACHEBE MM, Gafter-Gvili A
    How I treat anemia in pregnancy: iron, cobalamin and folate.
    Blood. 2016 Dec 29. pii: blood-2016-08-672246. doi: 10.1182/blood-2016-08-672246
    PubMed     Text format     Abstract available


  54. HUANG Q
    A striking bone marrow dyserythropoietic change but no anemia.
    Blood. 2016;128:3177.
    PubMed     Text format    


  55. CHANDRAKASAN S, Jayavaradhan R, Ernst J, Shrestha A, et al
    KIT Blockade Is Sufficient for Donor Hematopoietic Stem Cell Engraftment in Fanconi Anemia Mice.
    Blood. 2016 Dec 20. pii: blood-2015-12-689083. doi: 10.1182/blood-2015-12-689083
    PubMed     Text format    


  56. CROSSAN GP
    Metformin: treating the cause of Fanconi anemia?
    Blood. 2016;128:2748-2750.
    PubMed     Text format    


  57. GLUCKMAN E, Cappelli B, Bernaudin F, Labopin M, et al
    Sickle cell disease: an international survey of results of HLA-identical sibling hematopoietic stem cell transplantation.
    Blood. 2016 Dec 13. pii: blood-2016-10-745711.
    PubMed     Text format     Abstract available


  58. ABAN I, Baddam S, Hilliard LM, Howard TH, et al
    Severe anemia early in life as a risk factor for sickle cell kidney disease.
    Blood. 2016 Dec 5. pii: blood-2016-09-738104.
    PubMed     Text format    


    November 2016
  59. GARGIULO L, Zaimoku Y, Scappini B, Maruyama H, et al
    Glycosylphosphatidylinositol-specific T cells,IFNgamma-producing T cells,and pathogenesis of idiopathic aplastic anemia.
    Blood. 2016 Nov 30. pii: blood-2016-09-740845.
    PubMed     Text format    


  60. LIEM RI, Chan C, Vu TT, Fornage M, et al
    Longitudinal association among sickle cell trait, fitness, and cardiovascular disease risk factors in African Americans in CARDIA.
    Blood. 2016 Nov 16. pii: blood-2016-07-727719.
    PubMed     Text format     Abstract available


  61. MCGANN PT, Hernandez AG, Ware RE
    Sickle cell anemia in sub-Saharan Africa: advancing the clinical paradigm through partnerships and research.
    Blood. 2016 Nov 7. pii: blood-2016-09-702324.
    PubMed     Text format    



  62. Camitta BM, Thomas ED, Nathan DG, et al. Severe aplastic anemia: a prospective study of the effect of early marrow transplantation on acute mortality. Blood. 1976;48(1):63-70.
    Blood. 2016;128:2191.
    PubMed     Text format    


    October 2016
  63. ALJITAWI OS, Paul S, Ganguly A, Lin TL, et al
    Erythropoietin modulation is associated with improved homing and engraftment post umbilical cord blood transplantation.
    Blood. 2016 Oct 19. pii: blood-2016-05-715292.
    PubMed     Text format     Abstract available


  64. ZHANG QS, Tang W, Deater M, Phan N, et al
    Metformin improves defective hematopoiesis and delays tumor formation in Fanconi anemia mice.
    Blood. 2016 Oct 18. pii: blood-2015-11-683490.
    PubMed     Text format     Abstract available


    September 2016
  65. URRUTIA AA, Afzal A, Nelson J, Davidoff O, et al
    Prolyl-4-hydroxylase 2 and 3 co-regulate murine erythropoietin in brain pericytes.
    Blood. 2016 Sep 28. pii: blood-2016-05-713545.
    PubMed     Text format     Abstract available


    August 2016
  66. RUSSO R, Andolfo I, Manna F, De Rosa G, et al
    Increased levels of ERFE-encoding FAM132B in patients with congenital dyserythropoietic anemia type II.
    Blood. 2016 Aug 18. pii: blood-2016-06-724328.
    PubMed     Text format    


  67. BADE NA, Yared JA
    Unexpected babesiosis in a patient with worsening anemia after allogeneic hematopoietic stem cell transplantation.
    Blood. 2016;128:1019.
    PubMed     Text format    


  68. LICHTENSTEIN DA, Crispin AW, Sendamarai AK, Campagna DR, et al
    A recurring mutation in the respiratory complex 1 protein NDUFB11 is responsible for a novel form of X-linked sideroblastic anemia.
    Blood. 2016 Aug 3. pii: blood-2016-05-719062.
    PubMed     Text format     Abstract available


    June 2016

  69. MDS and AML in Fanconi anemia.
    Blood. 2016;127:3105.
    PubMed     Text format    


  70. KHAZAL S, Polishchuk V, Manwani D, Gallagher PG, et al
    Allogeneic bone marrow transplantation for treatment of severe hemolytic anemia attributable to hexokinase deficiency.
    Blood. 2016 Jun 13. pii: blood-2016-03-702860.
    PubMed     Text format    


  71. KORDASTI S, Costantini B, Seidl T, Perez Abellan P, et al
    Deep-phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment.
    Blood. 2016 Jun 8. pii: blood-2016-03-703702.
    PubMed     Text format     Abstract available


    May 2016

  72. Tanaka KR, Valentine WN, Miwa S. Pyruvate kinase (PK) deficiency hereditary nonspherocytic hemolytic anemia. Blood. 1962;19(3):267-295.
    Blood. 2016;127:2505.
    PubMed     Text format    


  73. BOUTAULT R, Eveillard M
    Acquired elliptocytosis in the setting of a refractory anemia with excess blasts and del(20q).
    Blood. 2016;127:2646.
    PubMed     Text format    



  74. Raab SO, Haut A, Cartwright GE, Wintrobe MM. Pyridoxine-responsive anemia. Blood. 1961;18(3):285-302.
    Blood. 2016;127:2365.
    PubMed     Text format    


  75. BARTNIKAS TB
    Matriptase-2 links erythropoietin to iron.
    Blood. 2016;127:2270-1.
    PubMed     Text format    


    April 2016
  76. OGAWA S
    Clonal hematopoiesis in acquired aplastic anemia.
    Blood. 2016 Apr 27. pii: blood-2016-01-636381.
    PubMed     Text format     Abstract available


  77. PERKINS A, Xu X, Higgs DR, Patrinos GP, et al
    Kruppeling erythropoiesis: an unexpected broad spectrum of human red blood cell disorders due to KLF1 variants.
    Blood. 2016;127:1856-62.
    PubMed     Text format     Abstract available


  78. LU Y, Hanada T, Fujiwara Y, Nwankwo JO, et al
    Gene disruption of dematin causes precipitous loss of erythrocyte membrane stability and severe hemolytic anemia.
    Blood. 2016 Apr 12. pii: blood-2016-01-692251.
    PubMed     Text format     Abstract available


  79. MCGANN PT
    Hydroxyurea for abnormal TCDs: safe to switch?
    Blood. 2016;127:1738-40.
    PubMed     Text format     Abstract available


    March 2016
  80. PEFFAULT DE LATOUR R, Soulier J
    How we diagnose and treat MDS and AML in Fanconi anemia.
    Blood. 2016 Mar 28. pii: blood-2016-01-583625.
    PubMed     Text format     Abstract available


  81. PINCEZ T, Guitton C, Gauthier F, de Lambert G, et al
    Long-term follow-up of subtotal splenectomy for hereditary spherocytosis: a single-center study.
    Blood. 2016;127:1616-8.
    PubMed     Text format    



  82. Giblett ER, Coleman DH, Pirzio-Biroli G, Donohue DM, Motulsky AG, Finch CA. Erythrokinetics: quantitative measurements of red cell production and destruction in normal subjects and patients with anemia. Blood. 1956;11(4):291-309.
    Blood. 2016;127:1375.
    PubMed     Text format    


  83. DULMOVITS BM, Appiah-Kubi AO, Papoin J, Hale J, et al
    Pomalidomide reverses gamma-globin silencing through the transcriptional reprogramming of adult hematopoietic progenitors.
    Blood. 2016;127:1481-92.
    PubMed     Text format     Abstract available



  84. Rosenthal MC, Pisciotta AV, Komninos ZD, Goldenberg H, Dameshek W. The auto-immune hemolytic anemia of malignant lymphocytic disease. Blood. 1955;10(3):197-227.
    Blood. 2016;127:1217.
    PubMed     Text format    


  85. SPARKENBAUGH EM, Chantrathammachart P, Chandarajoti K, Mackman N, et al
    Thrombin-independent contribution of tissue factor to inflammation and cardiac hypertrophy in a mouse model of sickle cell disease.
    Blood. 2016;127:1371-3.
    PubMed     Text format    


  86. KASSIM AA, Pruthi S, Day M, Rodeghier M, et al
    Silent cerebral infarcts and cerebral aneurysms are prevalent in adults with sickle cell anemia.
    Blood. 2016 Mar 3. pii: blood-2016-01-694562.
    PubMed     Text format    


    February 2016

  87. Dacie JV. Acquired hemolytic anemia: with special reference to the antiglobulin (Coombs') reaction. Blood. 1953;8(9):813-823.
    Blood. 2016;127:955.
    PubMed     Text format    


  88. DUMAS G, Habibi A, Onimus T, Merle JC, et al
    Eculizumab salvage therapy for delayed hemolysis transfusion reaction in sickle cell disease patients.
    Blood. 2016;127:1062-4.
    PubMed     Text format    


  89. LIU D, Yi S, Zhang X, Fang P, et al
    Human STEAP3 mutations with no phenotypic red cell changes.
    Blood. 2016;127:1067-71.
    PubMed     Text format    


  90. BAR C, Povedano JM, Serrano R, Benitez-Buelga C, et al
    Telomerase gene therapy rescues telomere length, bone marrow aplasia and survival in mice with aplastic anemia.
    Blood. 2016 Feb 22. pii: blood-2015-08-667485.
    PubMed     Text format     Abstract available


  91. DUROT E, Patey M
    Pure red cell aplasia revealing nonnodal mantle cell lymphoma.
    Blood. 2016;127:952.
    PubMed     Text format    



  92. Singer K, Fisher B. Studies on abnormal hemoglobins, VI: electrophoretic demonstration of type S (sickle cell) hemoglobin in erythrocytes incapable of showing the sickle cell phenomenon. Blood. 1953;8(3):270-275.
    Blood. 2016;127:791.
    PubMed     Text format    


  93. PARISE LV, Berliner N
    Sickle cell disease: challenges and progress.
    Blood. 2016;127:789.
    PubMed     Text format    


  94. TELEN MJ
    Beyond hydroxyurea: new and old drugs in the pipeline for sickle cell disease.
    Blood. 2016;127:810-9.
    PubMed     Text format     Abstract available


  95. DEBAUN MR, Kirkham FJ
    Central nervous system complications and management in sickle cell disease.
    Blood. 2016;127:829-38.
    PubMed     Text format     Abstract available


  96. HOBAN MD, Orkin SH, Bauer DE
    Genetic treatment of a molecular disorder: gene therapy approaches to sickle cell disease.
    Blood. 2016;127:839-48.
    PubMed     Text format     Abstract available


  97. ZHANG D, Xu C, Manwani D, Frenette PS, et al
    Neutrophils, platelets, and inflammatory pathways at the nexus of sickle cell disease pathophysiology.
    Blood. 2016;127:801-9.
    PubMed     Text format     Abstract available


  98. CHESNAIS V, Renneville A, Toma A, Lambert J, et al
    Effect of lenalidomide treatment on clonal architecture of myelodysplastic syndromes without 5q deletion.
    Blood. 2016;127:749-60.
    PubMed     Text format     Abstract available


  99. BERNAUDIN F, Verlhac S, Arnaud C, Kamdem A, et al
    Long term follow-up of children with sickle cell anemia treated for abnormal transcranial Doppler velocities.
    Blood. 2016 Feb 5. pii: blood-2015-10-675231.
    PubMed     Text format     Abstract available


    January 2016

  100. Dacie JV. Diagnosis and mechanism of hemolysis in chronic hemolytic anemia with nocturnal hemoglobinuria. Blood. 1949;4(11):1183-1195.
    Blood. 2016;127:371.
    PubMed     Text format    


  101. VINCHI F, Costa da Silva M, Ingoglia G, Petrillo S, et al
    Hemopexin therapy reverts heme-induced proinflammatory phenotypic switching of macrophages in a mouse model of sickle cell disease.
    Blood. 2016;127:473-86.
    PubMed     Text format     Abstract available


  102. THUNG I, Broome HE
    Hemophagocytosis in a patient with sickle cell disease.
    Blood. 2016;127:369.
    PubMed     Text format    


  103. VASANTHAKUMAR A, Arnovitz S, Marquez R, Lepore J, et al
    Brca1 deficiency causes bone marrow failure and spontaneous hematologic malignancies in mice.
    Blood. 2016;127:310-3.
    PubMed     Text format     Abstract available


  104. GORDEUK VR, Castro OL, Machado R
    Pathophysiology and treatment of pulmonary hypertension in sickle cell disease.
    Blood. 2016 Jan 12. pii: blood-2015-08-618561.
    PubMed     Text format     Abstract available


  105. NAI A, Rubio A, Campanella A, Gourbeyre O, et al
    Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice.
    Blood. 2016 Jan 11. pii: blood-2015-11-681494.
    PubMed     Text format     Abstract available


    November 2015
  106. BARAZIA A, Li J, Kim K, Shabrani N, et al
    Hydroxyurea with AKT2 inhibition decreases vaso-occlusive events in sickle cell disease mice.
    Blood. 2015;126:2511-7.
    PubMed     Text format     Abstract available


  107. MALINOWSKI AK, Shehata N, D'Souza R, Kuo KH, et al
    Prophylactic transfusion for pregnant women with sickle cell disease: a systematic review and meta-analysis.
    Blood. 2015;126:2424-35.
    PubMed     Text format     Abstract available


  108. BRODSKY RA
    Complement in hemolytic anemia.
    Blood. 2015 Nov 18. pii: blood-2015-06-640995.
    PubMed     Text format     Abstract available


  109. DALLE CARBONARE L, Matte' A, Valenti MT, Siciliano A, et al
    Hypoxia-reperfusion affects osteogenic lineage and promotes sickle cell bone disease.
    Blood. 2015;126:2320-8.
    PubMed     Text format     Abstract available


  110. GORDEUK VR
    Osteoclast activation and sickle bone disease.
    Blood. 2015;126:2259-60.
    PubMed     Text format    


    October 2015
  111. CONWAY EM
    HUS and the case for complement.
    Blood. 2015;126:2085-90.
    PubMed     Text format     Abstract available


  112. SCHRIER SL
    So you know how to treat iron deficiency anemia.
    Blood. 2015;126:1971.
    PubMed     Text format    


  113. DANESHBOD Y, Kazemi T
    Nodal extramedullary hematopoiesis and facial bone change in thalassemia.
    Blood. 2015;126:2070.
    PubMed     Text format    


  114. MOURA IC, Hermine O
    Erythroferrone: the missing link in beta-thalassemia?
    Blood. 2015;126:1974-5.
    PubMed     Text format     Abstract available


  115. KAUTZ L, Jung G, Du X, Gabayan V, et al
    Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of beta-thalassemia.
    Blood. 2015;126:2031-7.
    PubMed     Text format     Abstract available


  116. SCHMITZ-ABE K, Ciesielski SJ, Schmidt PJ, Campagna DR, et al
    Congenital sideroblastic anemia due to mutations in the mitochondrial HSP70 homologue HSPA9.
    Blood. 2015 Oct 21. pii: blood-2015-09-659854.
    PubMed     Text format     Abstract available


  117. RENNEVILLE A, Van Galen P, Canver MC, McConkey M, et al
    EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.
    Blood. 2015;126:1930-9.
    PubMed     Text format     Abstract available


  118. PAWLINSKI R
    It's "PT" for SCD!
    Blood. 2015;126:1739-40.
    PubMed     Text format     Abstract available


  119. DISCHER DE, Ney PA
    The reason sickle reticulocytes expose PS.
    Blood. 2015;126:1737-8.
    PubMed     Text format     Abstract available


  120. ARUMUGAM PI, Mullins ES, Shanmukhappa SK, Monia BP, et al
    Genetic diminution of circulating prothrombin ameliorates multiorgan pathologies in sickle cell disease mice.
    Blood. 2015;126:1844-55.
    PubMed     Text format     Abstract available


  121. MANKELOW TJ, Griffiths RE, Trompeter S, Flatt JF, et al
    Autophagic vesicles on mature human reticulocytes explain phosphatidylserine-positive red cells in sickle cell disease.
    Blood. 2015;126:1831-4.
    PubMed     Text format     Abstract available


  122. ESTEPP JH
    MAGiC: VOC remains but kids with SCA appear.
    Blood. 2015;126:1637-8.
    PubMed     Text format     Abstract available


  123. BROUSSEAU DC, Scott JP, Badaki-Makun O, Darbari DS, et al
    A multicenter randomized controlled trial of intravenous magnesium for sickle cell pain crisis in children.
    Blood. 2015;126:1651-7.
    PubMed     Text format     Abstract available


    September 2015
  124. GRYGORCZYK R, Mohandas N
    More than one way to shrink.
    Blood. 2015;126:1263-4.
    PubMed     Text format    


  125. GLOGOWSKA E, Lezon-Geyda K, Maksimova Y, Schulz VP, et al
    Mutations in the Gardos channel (KCNN4) are associated with hereditary xerocytosis.
    Blood. 2015;126:1281-4.
    PubMed     Text format     Abstract available


  126. RAPETTI-MAUSS R, Lacoste C, Picard V, Guitton C, et al
    A mutation in the Gardos channel is associated with hereditary xerocytosis.
    Blood. 2015;126:1273-80.
    PubMed     Text format     Abstract available


  127. BELISARIO AR, Sales RR, Toledo NE, Velloso-Rodrigues C, et al
    Association between ENPP1 K173Q and stroke in a newborn cohort of 395 Brazilian children with sickle cell anemia.
    Blood. 2015;126:1259-60.
    PubMed     Text format    


    August 2015
  128. ROUMENINA LT
    C3dg-CR3 interaction in erythrophagocytosis.
    Blood. 2015;126:828-9.
    PubMed     Text format     Abstract available


  129. LIN Z, Schmidt CQ, Koutsogiannaki S, Ricci P, et al
    Complement C3dg-mediated erythrophagocytosis: implications for paroxysmal nocturnal hemoglobinuria.
    Blood. 2015;126:891-4.
    PubMed     Text format     Abstract available


  130. KASSIM AA, Payne AB, Rodeghier M, Macklin EA, et al
    Forced expiratory volume in 1 second is associated with earlier death in sickle cell anemia.
    Blood. 2015 Aug 10. pii: blood-2015-05-644435.
    PubMed     Text format     Abstract available


  131. HRISINKO MA, Chen YH
    Rasburicase-induced Heinz body hemolytic anemia in a patient with chronic lymphocytic leukemia.
    Blood. 2015;126:826.
    PubMed     Text format    


  132. GLADWIN MT
    Revisiting the hyperhemolysis paradigm.
    Blood. 2015;126:695-6.
    PubMed     Text format     Abstract available


  133. DETTERICH JA, Kato RM, Rabai M, Meiselman HJ, et al
    Chronic transfusion therapy improves but does not normalize systemic and pulmonary vasculopathy in sickle cell disease.
    Blood. 2015;126:703-10.
    PubMed     Text format     Abstract available


  134. ALMEIDA CB, Souza LE, Leonardo FC, Costa FT, et al
    Acute hemolytic vascular inflammatory processes are prevented by nitric oxide replacement or a single dose of hydroxyurea.
    Blood. 2015;126:711-20.
    PubMed     Text format     Abstract available


    July 2015
  135. KRIVEGA I, Byrnes C, de Vasconcellos JF, Lee YT, et al
    Inhibition of G9a methyltransferase stimulates fetal hemoglobin production by facilitating LCR/gamma-globin looping.
    Blood. 2015;126:665-72.
    PubMed     Text format     Abstract available


  136. CUI S, Lim KC, Shi L, Lee M, et al
    The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice.
    Blood. 2015;126:386-96.
    PubMed     Text format     Abstract available


  137. RADICH J
    Splicing up the classification of myelodysplasia.
    Blood. 2015;126:128-9.
    PubMed     Text format    


  138. MALCOVATI L, Karimi M, Papaemmanuil E, Ambaglio I, et al
    SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts.
    Blood. 2015;126:233-41.
    PubMed     Text format     Abstract available


    June 2015
  139. EAR J, Huang H, Wilson T, Tehrani Z, et al
    RAP-011 improves erythropoiesis in zebrafish model of Diamond-Blackfan anemia through antagonizing lefty1.
    Blood. 2015 Jun 24. pii: blood-2015-01-622522.
    PubMed     Text format     Abstract available


  140. KARPONI G, Psatha N, Lederer CW, Adair JE, et al
    Plerixafor+G-CSF-mobilized CD34+ cells represent an optimal graft source for thalassemia gene therapy.
    Blood. 2015 Jun 18. pii: blood-2015-03-629618.
    PubMed     Text format     Abstract available


  141. MECABO G, Yamamoto M, Biassi TP, Figueiredo MS, et al
    Lactate dehydrogenase isoenzyme 3 and hemolysis in sickle cell anemia: a possible correlation?
    Blood. 2015;125:3821-2.
    PubMed     Text format    


  142. GLUCKMAN E
    Improving survival for Fanconi anemia patients.
    Blood. 2015;125:3676.
    PubMed     Text format    


  143. VERCELLOTTI GM
    Special delivery: microparticles convey heme.
    Blood. 2015;125:3677-8.
    PubMed     Text format     Abstract available


  144. METTANANDA S, Gibbons RJ, Higgs DR
    alpha-Globin as a molecular target in the treatment of beta-thalassemia.
    Blood. 2015;125:3694-701.
    PubMed     Text format     Abstract available


  145. CAMUS SM, De Moraes JA, Bonnin P, Abbyad P, et al
    Circulating cell membrane microparticles transfer heme to endothelial cells and trigger vasoocclusions in sickle cell disease.
    Blood. 2015;125:3805-14.
    PubMed     Text format     Abstract available


  146. STEENSMA DP, Sasu BJ, Sloan JA, Tomita DK, et al
    Serum hepcidin levels predict response to intravenous iron and darbepoetin in chemotherapy-associated anemia.
    Blood. 2015;125:3669-71.
    PubMed     Text format    


  147. OKAM MM, Esrick EB, Mandell E, Campigotto F, et al
    Phase 1/2 trial of vorinostat in patients with sickle cell disease who have not benefitted from hydroxyurea.
    Blood. 2015;125:3668-9.
    PubMed     Text format    


  148. SADLER JE
    Atypical HUS may become a diagnosis of inclusion.
    Blood. 2015;125:3525-6.
    PubMed     Text format     Abstract available


  149. KUHRT D, Wojchowski DM
    Emerging EPO and EPO receptor regulators and signal transducers.
    Blood. 2015;125:3536-41.
    PubMed     Text format     Abstract available


  150. GAVRIILAKI E, Yuan X, Ye Z, Ambinder AJ, et al
    Modified Ham test for atypical hemolytic uremic syndrome.
    Blood. 2015;125:3637-46.
    PubMed     Text format     Abstract available


  151. ANELE UA, Le BV, Resar LM, Burnett AL, et al
    How I treat priapism.
    Blood. 2015;125:3551-8.
    PubMed     Text format     Abstract available


    May 2015
  152. FRAIMAN YS, Moliterno AR
    High-density genomic analysis reveals basis of spherocytosis in myelodysplastic syndrome.
    Blood. 2015;125:3517.
    PubMed     Text format    


  153. KASSIM AA, Galadanci NA, Pruthi S, DeBaun MR, et al
    How I treat and manage strokes in sickle cell disease.
    Blood. 2015;125:3401-10.
    PubMed     Text format     Abstract available


  154. DE MONTALEMBERT M, Deneux-Tharaux C
    Pregnancy in sickle cell disease is at very high risk.
    Blood. 2015;125:3216-7.
    PubMed     Text format    


  155. COFIELL R, Kukreja A, Bedard K, Yan Y, et al
    Eculizumab reduces complement activation, inflammation, endothelial damage, thrombosis, and renal injury markers in aHUS.
    Blood. 2015;125:3253-62.
    PubMed     Text format     Abstract available


  156. OTENG-NTIM E, Meeks D, Seed PT, Webster L, et al
    Adverse maternal and perinatal outcomes in pregnant women with sickle cell disease: systematic review and meta-analysis.
    Blood. 2015;125:3316-25.
    PubMed     Text format     Abstract available


    April 2015
  157. TOLAR J
    Sickle cell and silent spleen.
    Blood. 2015;125:2589-90.
    PubMed     Text format     Abstract available


  158. TELEN MJ, Wun T, McCavit TL, De Castro LM, et al
    Randomized phase 2 study of GMI-1070 in SCD: reduction in time to resolution of vaso-occlusive events and decreased opioid use.
    Blood. 2015;125:2656-64.
    PubMed     Text format     Abstract available


  159. HOBAN MD, Cost GJ, Mendel MC, Romero Z, et al
    Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells.
    Blood. 2015;125:2597-604.
    PubMed     Text format     Abstract available


  160. ANDERSEN GR
    Mutations in complement C3 from aHUS patients.
    Blood. 2015;125:2316-8.
    PubMed     Text format     Abstract available


  161. MAGOR GW, Tallack MR, Gillinder KR, Bell CC, et al
    KLF1-null neonates display hydrops fetalis and a deranged erythroid transcriptome.
    Blood. 2015;125:2405-17.
    PubMed     Text format     Abstract available


  162. SCHRAMM EC, Roumenina LT, Rybkine T, Chauvet S, et al
    Mapping interactions between complement C3 and regulators using mutations in atypical hemolytic uremic syndrome.
    Blood. 2015;125:2359-69.
    PubMed     Text format     Abstract available


    March 2015
  163. SIEGEMUND S, Rigaud S, Conche C, Broaten B, et al
    IP3 3-kinase B controls hematopoietic stem cell homeostasis and prevents lethal hematopoietic failure in mice.
    Blood. 2015 Mar 18. pii: blood-2014-06-583187.
    PubMed     Text format     Abstract available


  164. PAESSLER M, Hartung H
    Dehydrated hereditary stomatocytosis masquerading as MDS.
    Blood. 2015;125:1841.
    PubMed     Text format    


  165. XIANG J, Wu DC, Chen Y, Paulson RF, et al
    In vitro culture of stress erythroid progenitors identifies distinct progenitor populations and analogous human progenitors.
    Blood. 2015;125:1803-12.
    PubMed     Text format     Abstract available


    February 2015
  166. RASHIDI A, Fisher SI
    Unwelcome passengers.
    Blood. 2015;125:1507.
    PubMed     Text format    


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