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Articles published in Haematologica

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Single Articles


    October 2017
  1. CLUZEAU T, McGraw KL, Irvine B, Masala E, et al
    Pro-inflammatory proteins S100A9 and TNFalpha suppress erythropoietin elaboration in myelodysplastic syndromes.
    Haematologica. 2017 Oct 5. pii: haematol.2016.158857.
    PubMed     Text format     Abstract available


    September 2017
  2. VENUGOPAL P, Moore S, Lawrence DM, George AJ, et al
    Self-reverting mutations partially correct the blood phenotype in a Diamond Blackfan Anemia patient.
    Haematologica. 2017 Sep 29. pii: haematol.2017.166678.
    PubMed     Text format    


    August 2017
  3. CLINKENBEARD EL, Hanudel MR, Stayrook KR, Appaiah HN, et al
    Erythropoietin stimulates murine and human Fibroblast growth factor-23, revealing novel roles for bone and bone marrow.
    Haematologica. 2017 Aug 17. pii: haematol.2017.167882.
    PubMed     Text format    


    July 2017
  4. VAHT K, Goransson M, Carlson K, Isaksson C, et al
    Incidence and outcome of acquired aplastic anemia-real-world data from patients diagnosed in Sweden from 2000-2011.
    Haematologica. 2017 Jul 27. pii: haematol.2017.169862.
    PubMed     Text format     Abstract available


  5. VAN DER HEM JG, de Wreede LC, Brand A, Veelken H, et al
    Long-term risk of cancer development in adult patients with idiopathic aplastic anemia after treatment with anti-thymocyte globulin.
    Haematologica. 2017 Jul 13. pii: haematol.2017.171215.
    PubMed     Text format    


  6. BACIGALUPO A
    Antithymocyte globulin and transplants for aplastic anemia.
    Haematologica. 2017;102:1137-1138.
    PubMed     Text format    


    June 2017
  7. OTTO JM, Plumb JOM, Clissold E, Kumar S, et al
    Hemoglobin concentration, total hemoglobin mass and plasma volume in patients: implications for anemia.
    Haematologica. 2017 Jun 8. pii: haematol.2017.169680.
    PubMed     Text format     Abstract available


    May 2017
  8. RUSSO R, Andolfo I, Gambale A, De Rosa G, et al
    GATA1 erythroid-specific regulation of SEC23B expression and its implication in the pathogenesis of Congenital Dyserythropoietic Anemia type II.
    Haematologica. 2017 May 26. pii: haematol.2016.162966.
    PubMed     Text format    


    April 2017
  9. MAITRA P, Caughey M, Robinson L, Desai PC, et al
    Risk factors for mortality in adult patients with sickle cell disease: a meta-analysis of studies in North America and Europe.
    Haematologica. 2017;102:626-636.
    PubMed     Text format     Abstract available


  10. PIEL FB, Tewari S, Brousse V, Analitis A, et al
    Associations between environmental factors and hospital admissions for sickle cell disease.
    Haematologica. 2017;102:666-675.
    PubMed     Text format     Abstract available


    March 2017
  11. ZHOU Y, He Y, Xing W, Zhang P, et al
    Abnormal bone marrow microenvironment contributes to hematopoietic dysfunction in Fanconi anemia.
    Haematologica. 2017 Mar 24. pii: haematol.2016.158717.
    PubMed     Text format     Abstract available


  12. KEKRE N, Zhang Y, Zhang MJ, Carreras J, et al
    Effect of antithymocyte globulin source on outcomes of bone marrow transplantation for severe aplastic anemia.
    Haematologica. 2017 Mar 24. pii: haematol.2017.164459.
    PubMed     Text format     Abstract available


  13. KOBAYASHI M, Kato H, Hada H, Itoh-Nakadai A, et al
    Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency.
    Haematologica. 2017;102:454-465.
    PubMed     Text format     Abstract available


  14. YUAN X, Gavriilaki E, Thanassi JA, Yang G, et al
    Small-molecule factor D inhibitors selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome.
    Haematologica. 2017;102:466-475.
    PubMed     Text format     Abstract available


    February 2017
  15. MILLOT S, Delaby C, Moulouel B, Lefebvre T, et al
    Hemolytic anemia repressed hepcidin level without hepatocyte iron overload: lesson from Gunther disease model.
    Haematologica. 2017;102:260-270.
    PubMed     Text format     Abstract available


  16. SRIVASTAVA A, Shaji RV
    Cure for thalassemia major - from allogeneic hematopoietic stem cell transplantation to gene therapy.
    Haematologica. 2017;102:214-223.
    PubMed     Text format     Abstract available


  17. KIM K, Li J, Barazia A, Tseng A, et al
    ARQ 092, an orally-available, selective AKT inhibitor, attenuates neutrophil-platelet interactions in sickle cell disease.
    Haematologica. 2017;102:246-259.
    PubMed     Text format     Abstract available


  18. XIN J, Breslin P, Wei W, Li J, et al
    Necroptosis in spontaneously-mutated hematopoietic cells induces autoimmune bone marrow failure in mice.
    Haematologica. 2017;102:295-307.
    PubMed     Text format     Abstract available


    January 2017
  19. BELL JB, Abedin S, Platanias LC
    Circulating microRNAs: promising biomarkers in aplastic anemia.
    Haematologica. 2017;102:1-2.
    PubMed     Text format    


    December 2016
  20. CRAZZOLARA R, Kropshofer G, Haas OA, Matthes-Martin S, et al
    Reduced-intensity conditioning and stem cell transplantation in infants with Diamond Blackfan anemia.
    Haematologica. 2016 Dec 7. pii: haematol.2016.157149.
    PubMed     Text format    


  21. IKEDA F, Yoshida K, Toki T, Uechi T, et al
    Exome sequencing identified RPS15A as a novel causative gene for Diamond-Blackfan anemia.
    Haematologica. 2016 Dec 1. pii: haematol.2016.153932.
    PubMed     Text format    


    November 2016
  22. HANUDEL MR, Rappaport M, Gabayan V, Jung G, et al
    Increased serum hepcidin contributes to the anemia of chronic kidney disease in a murine model.
    Haematologica. 2016 Nov 24. pii: haematol.2016.150433.
    PubMed     Text format    


    September 2016
  23. LATOUR C, Wlodarczyk MF, Jung G, Gineste A, et al
    Erythroferrone contributes to hepcidin repression in a mouse model of malarial anemia.
    Haematologica. 2016 Sep 22. pii: haematol.2016.150227.
    PubMed     Text format     Abstract available


  24. HOSOKAWA K, Kajigaya S, Feng X, Desierto MJ, et al
    A plasma microRNA signature as a biomarker for acquired aplastic anemia.
    Haematologica. 2016 Sep 22. pii: haematol.2016.151076.
    PubMed     Text format     Abstract available


  25. SARAF SL, Shah BN, Zhang X, Han J, et al
    APOL1, Alpha thalassemia, and BCL11A variants as a genetic risk profile for progression of chronic kidney disease in sickle cell anemia.
    Haematologica. 2016 Sep 22. pii: haematol.2016.154153.
    PubMed     Text format    


  26. CUGLIEVAN B, DePombo A, De Angulo G
    Aplastic anemia: the correct nomenclature matters.
    Haematologica. 2016;101:e391.
    PubMed     Text format    


  27. GUPTA V, Harrison C, Hexner EO, Al-Ali HK, et al
    The impact of anemia on overall survival in patients with myelofibrosis treated with ruxolitinib in the COMFORT studies.
    Haematologica. 2016 Sep 1. pii: haematol.2016.151449.
    PubMed     Text format    


    August 2016
  28. GREIL J, Verga-Falzacappa MV, Echner NE, Behnisch W, et al
    Mutating heme oxygenase-1 into a peroxidase causes a defect in bilirubin synthesis associated with microcytic anemia and severe hyperinflammation.
    Haematologica. 2016 Aug 4. pii: haematol.2016.147090.
    PubMed     Text format    


    July 2016
  29. KEEL SB, Scott A, Sanchez-Bonilla M, Ho PA, et al
    Genetic features of myelodysplastic syndrome and aplastic anemia in pediatric and young adult patients.
    Haematologica. 2016 Jul 14. pii: haematol.2016.149476.
    PubMed     Text format     Abstract available


    May 2016
  30. SUZUKI N, Sasaki Y, Kato K, Yamazaki S, et al
    Efficacy estimation of erythropoiesis-stimulating agents using erythropoietin-deficiency anemic mice.
    Haematologica. 2016 May 31. pii: haematol.2015.140814.
    PubMed     Text format    


    April 2016
  31. DEVILLIER R, Dalle JH, Kulasekararaj A, D' Aveni M, et al
    Unrelated alternative donor transplantation for severe acquired aplastic anemia: a study from the French Society of Bone Marrow Transplantation and Cell Therapies and the Severe Aplastic Anemia Working Party of EBMT.
    Haematologica. 2016 Apr 7. pii: haematol.2015.138727.
    PubMed     Text format     Abstract available


  32. DE FALCO L, Bruno M, Yilmaz-Keskin E, Sal E, et al
    The role of Matriptase-2 during the early postnatal development in humans.
    Haematologica. 2016;101:e126-8.
    PubMed     Text format    


    March 2016
  33. KOVAC S, Boser P, Cui Y, Ferring-Appel D, et al
    Anti-hemojuvelin antibody corrects anemia caused by inappropriately high hepcidin levels.
    Haematologica. 2016 Mar 4. pii: haematol.2015.140772.
    PubMed     Text format    


  34. ARASHIKI N, Takakuwa Y, Mohandas N, Hale J, et al
    ATP11C is a major flippase in human erythrocytes and its defect causes congenital hemolytic anemia.
    Haematologica. 2016 Mar 4. pii: haematol.2016.142273.
    PubMed     Text format     Abstract available


  35. CHEN H, Choesang T, Li H, Sun S, et al
    Increased hepcidin in transferrin-treated thalassemic mice correlates with increased liver BMP2 expression and decreased hepatocyte ERK activation.
    Haematologica. 2016;101:297-308.
    PubMed     Text format     Abstract available


    February 2016
  36. ARAI Y, Kondo T, Yamazaki H, Takenaka K, et al
    Allogeneic unrelated bone marrow transplantation from older donors results in worse prognosis in recipients with aplastic anemia.
    Haematologica. 2016 Feb 8. pii: haematol.2015.139469.
    PubMed     Text format     Abstract available


  37. ANGERMEIER E, Domes K, Lukowski R, Schlossmann J, et al
    Iron deficiency anemia in cyclic GMP kinase knockout mice.
    Haematologica. 2016;101:e48-51.
    PubMed     Text format    


  38. NGUYEN KL, Tian X, Alam S, Mehari A, et al
    Elevated transpulmonary gradient and cardiac magnetic resonance-derived right ventricular remodeling predict poor outcomes in sickle cell disease.
    Haematologica. 2016;101:e40-3.
    PubMed     Text format    


  39. VALVERDE Y, Benson B, Gupta M, Gupta K, et al
    Spinal glial activation and oxidative stress are alleviated by treatment with curcumin or coenzyme Q in sickle mice.
    Haematologica. 2016;101:e44-7.
    PubMed     Text format    


    January 2016
  40. MORISHIMA S, Kashiwase K, Matsuo K, Azuma F, et al
    High risk HLA alleles for severe acute graft-versus-host disease and mortality in unrelated donor bone marrow transplantation.
    Haematologica. 2016 Jan 14. pii: haematol.2015.136903.
    PubMed     Text format     Abstract available


  41. SHMUKLER BE, Lawson ND, Paw BH, Alper SL, et al
    Authors' response to "Comment on: 'Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia'".
    Haematologica. 2016;101:e39.
    PubMed     Text format    


  42. FAUCHERRE A, Kissa K, Nargeot J, Mangoni ME, et al
    Comment on: 'Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia'.
    Haematologica. 2016;101:e38.
    PubMed     Text format    


  43. SATO K, Feng X, Chen J, Li J, et al
    PPARgamma antagonist attenuates mouse immune-mediated bone marrow failure by inhibition of T cell function.
    Haematologica. 2016;101:57-67.
    PubMed     Text format     Abstract available


  44. CASU C, Aghajan M, Oikonomidou PR, Guo S, et al
    Combination of Tmprss6- ASO and the iron chelator deferiprone improves erythropoiesis and reduces iron overload in a mouse model of beta-thalassemia intermedia.
    Haematologica. 2016;101:e8-e11.
    PubMed     Text format    


  45. DE SWART L, Hendriks JC, van der Vorm LN, Cabantchik ZI, et al
    Second international round robin for the quantification of serum non-transferrin-bound iron and labile plasma iron in patients with iron-overload disorders.
    Haematologica. 2016;101:38-45.
    PubMed     Text format     Abstract available


    December 2015
  46. VINCENT L, Vang D, Nguyen J, Benson B, et al
    Cannabinoid receptor-specific mechanisms to ameliorate pain in sickle cell anemia via inhibition of mast cell activation and neurogenic inflammation.
    Haematologica. 2015 Dec 24. pii: haematol.2015.136523.
    PubMed     Text format     Abstract available


  47. RISITANO AM, Marotta S, Calzone R, Grimaldi F, et al
    Twenty years of the Italian Fanconi Anemia Registry: where we stand and what remains to be learned.
    Haematologica. 2015 Dec 3. pii: haematol.2015.133520.
    PubMed     Text format     Abstract available


    November 2015
  48. WARD D, Carter D, Homer M, Marucci L, et al
    Mathematical modelling reveals differential effects of erythropoietin on proliferation and lineage commitment of human hematopoietic progenitors in early erythroid culture.
    Haematologica. 2015 Nov 20. pii: haematol.2015.133637.
    PubMed     Text format     Abstract available


    October 2015
  49. OKAM MM, Koch TA, Tran MH
    Iron deficiency anemia treatment response to oral iron therapy: a pooled analysis of five randomized controlled trials.
    Haematologica. 2015 Oct 30. pii: haematol.2015.129114.
    PubMed     Text format    


    September 2015
  50. MEULENBROEK EM, De Haas M, Brouwer C, Folman C, et al
    Complement deposition in Autoimmune Hemolytic Anemia is a footprint for difficult-to-detect IgM-autoantibodies.
    Haematologica. 2015 Sep 9. pii: haematol.2015.128991.
    PubMed     Text format     Abstract available


  51. HOSOKAWA K, Muranski P, Feng X, Keyvanfar K, et al
    Identification of novel microRNA signatures linked to acquired aplastic anemia.
    Haematologica. 2015 Sep 9. pii: haematol.2015.126128.
    PubMed     Text format     Abstract available


  52. DROR Y, Cada M
    Response to comments from Drs. Alter and Rosenberg.
    Haematologica. 2015;100:e381-2.
    PubMed     Text format    


  53. ALTER BP, Rosenberg PS
    Comment on: "The impact of category, cytopathology and cytogenetics on development and progression of clonal and malignant myeloid transformation in inherited bone marrow failure syndromes".
    Haematologica. 2015;100:e378.
    PubMed     Text format    


  54. TEWARI S, Brousse V, Piel FB, Menzel S, et al
    Environmental determinants of severity in sickle cell disease.
    Haematologica. 2015;100:1108-16.
    PubMed     Text format     Abstract available


    August 2015
  55. NARITA A, Muramatsu H, Sekiya Y, Okuno Y, et al
    Paroxysmal nocturnal hemoglobinuria and telomere length predicts response to immunosuppressive therapy in pediatric aplastic anemia.
    Haematologica. 2015 Aug 27. pii: haematol.2015.132530.
    PubMed     Text format     Abstract available


  56. SHMUKLER BE, Huston NC, Thon JN, Ni CW, et al
    Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia.
    Haematologica. 2015 Aug 20. pii: haematol.2015.132449.
    PubMed     Text format    


  57. HAMA A, Takahashi Y, Muramatsu H, Ito M, et al
    Comparison of long-term outcomes between children with aplastic anemia and refractory cytopenia of childhood who received immunosuppressive therapy with antithymocyte globulin and cyclosporine.
    Haematologica. 2015 Aug 13. pii: haematol.2015.128553.
    PubMed     Text format     Abstract available


  58. ONCLINX C, Dogne S, Jadin L, Andris F, et al
    Deficiency in mouse hyaluronidase 2: a new mechanism of chronic thrombotic microangiopathy.
    Haematologica. 2015;100:1023-30.
    PubMed     Text format     Abstract available


  59. HAPGOOD G, Walsh T, Cukierman R, Paul E, et al
    Erythropoiesis is not equally suppressed in transfused males and females with beta-thalassemia major: are there clinical implications?
    Haematologica. 2015;100:e292-4.
    PubMed     Text format    


    July 2015
  60. BAR C, Huber N, Beier F, Blasco MA, et al
    Therapeutic effect of androgen therapy in a mouse model of aplastic anemia produced by short telomeres.
    Haematologica. 2015 Jul 23. pii: haematol.2015.129239.
    PubMed     Text format     Abstract available


  61. LEMONNE N, Charlot K, Waltz X, Ballas SK, et al
    Hydroxyurea treatment does not increase blood viscosity and improves red blood cell rheology in sickle cell anemia.
    Haematologica. 2015 Jul 2. pii: haematol.2015.130435.
    PubMed     Text format    


  62. KALISH BT, Matte A, Andolfo I, Iolascon A, et al
    Dietary omega-3 fatty acids protect against vasculopathy in a transgenic mouse model of sickle cell disease.
    Haematologica. 2015;100:870-80.
    PubMed     Text format     Abstract available


  63. KONOPLEVA M, Thall PF, Yi CA, Borthakur G, et al
    Phase I/II study of the hypoxia-activated prodrug PR104 in refractory/relapsed acute myeloid leukemia and acute lymphoblastic leukemia.
    Haematologica. 2015;100:927-34.
    PubMed     Text format     Abstract available


    June 2015
  64. LOPES FC, Traina F, Almeida CB, Leonardo FC, et al
    Key endothelial cell angiogenic mechanisms are stimulated by the circulating milieu in sickle cell disease and attenuated by hydroxyurea.
    Haematologica. 2015;100:730-9.
    PubMed     Text format     Abstract available


    May 2015
  65. AUERBACH M, Adamson J, Bircher A, Breymann C, et al
    On the safety of intravenous iron, evidence trumps conjecture.
    Haematologica. 2015;100:e214-5.
    PubMed     Text format    


  66. NARLA A, Mohandas N
    Jekyll and Hyde: the role of heme oxygenase-1 in erythroid biology.
    Haematologica. 2015;100:567-8.
    PubMed     Text format    


  67. REES DC, Thein SL, Osei A, Drasar E, et al
    The clinical significance of K-Cl cotransport activity in red cells of patients with HbSC disease.
    Haematologica. 2015;100:595-600.
    PubMed     Text format     Abstract available


  68. CADA M, Segbefia CI, Klaassen R, Fernandez CV, et al
    The impact of category, cytopathology and cytogenetics on development and progression of clonal and malignant myeloid transformation in inherited bone marrow failure syndromes.
    Haematologica. 2015;100:633-42.
    PubMed     Text format     Abstract available


  69. FRASER ST, Midwinter RG, Coupland LA, Kong S, et al
    Heme oxygenase-1 deficiency alters erythroblastic island formation, steady-state erythropoiesis and red blood cell lifespan in mice.
    Haematologica. 2015;100:601-10.
    PubMed     Text format     Abstract available


  70. AMID A, Cheong M, Eng B, Hanna M, et al
    Hb S/beta+-thalassemia due to Hb sickle and a novel deletion of DNase I hypersensitive sites HS3 and HS4 of the beta locus control region.
    Haematologica. 2015;100:e166-8.
    PubMed     Text format    


  71. ORIGA R, Cazzola M, Mereu E, Danjou F, et al
    Differences in the erythropoiesis-hepcidin-iron store axis between hemoglobin H disease and beta-thalassemia intermedia.
    Haematologica. 2015;100:e169-71.
    PubMed     Text format    


    April 2015
  72. MICHALLET AS, Guillermin Y, Deau B, Lebras L, et al
    Sequential combination of gemcitabine, vinorelbine, pegylated liposomal doxorubicin and Brentuximab as a bridge regimen to transplant in relapsed or refractory Hodgkin lymphoma.
    Haematologica. 2015 Apr 3. pii: haematol.2015.124784.
    PubMed     Text format     Abstract available


  73. RIVELLA S
    beta-thalassemias: paradigmatic diseases for scientific discoveries and development of innovative therapies.
    Haematologica. 2015;100:418-30.
    PubMed     Text format     Abstract available


  74. COLELLA MP, de Paula EV, Machado-Neto JA, Conran N, et al
    Elevated hypercoagulability markers in hemoglobin SC disease.
    Haematologica. 2015;100:466-71.
    PubMed     Text format     Abstract available


  75. ISHIKAWA Y, Maeda M, Pasham M, Aguet F, et al
    Role of the clathrin adaptor PICALM in normal hematopoiesis and polycythemia vera pathophysiology.
    Haematologica. 2015;100:439-51.
    PubMed     Text format     Abstract available


  76. DANJOU F, Francavilla M, Anni F, Satta S, et al
    A genetic score for the prediction of beta-thalassemia severity.
    Haematologica. 2015;100:452-7.
    PubMed     Text format     Abstract available


    March 2015
  77. SPARKENBAUGH EM, Chantrathammachart P, Wang S, Jonas W, et al
    Excess of heme induces tissue factor-dependent activation of coagulation in mice.
    Haematologica. 2015;100:308-14.
    PubMed     Text format     Abstract available


  78. KITSATI N, Liakos D, Ermeidi E, Mantzaris MD, et al
    Rapid elevation of transferrin saturation and serum hepcidin concentration in hemodialysis patients after intravenous iron infusion.
    Haematologica. 2015;100:e80-3.
    PubMed     Text format    


  79. AALBERS AM, van den Heuvel-Eibrink MM, Baumann I, Dworzak M, et al
    Bone marrow immunophenotyping by flow cytometry in refractory cytopenia of childhood.
    Haematologica. 2015;100:315-23.
    PubMed     Text format     Abstract available


  80. LUDWIG H, Rauch E, Kuehr T, Adam Z, et al
    Lenalidomide and dexamethasone for acute light chain-induced renal failure: a phase II study.
    Haematologica. 2015;100:385-91.
    PubMed     Text format     Abstract available


  81. ROSSIO R, Lotta LA, Pontiggia S, Borsa NG, et al
    A novel CD46 mutation in a patient with microangiopathy clinically resembling thrombotic thrombocytopenic purpura and normal ADAMTS13 activity.
    Haematologica. 2015;100:e87-9.
    PubMed     Text format    


    February 2015
  82. GUTSCHOW P, Schmidt PJ, Han H, Ostland V, et al
    A competitive enzyme-linked immunosorbent assay specific for murine hepcidin-1: correlation with hepatic mRNA expression in established and novel models of dysregulated iron homeostasis.
    Haematologica. 2015;100:167-77.
    PubMed     Text format     Abstract available


    January 2015
  83. IOLASCON A, Andolfo I, Russo R
    Red cells in post-genomic era: impact of personalized medicine in the treatment of anemias.
    Haematologica. 2015;100:3-6.
    PubMed     Text format    


  84. SATCHWELL TJ, Hawley BR, Bell AJ, Ribeiro ML, et al
    The cytoskeletal binding domain of band 3 is required for multiprotein complex formation and retention during erythropoiesis.
    Haematologica. 2015;100:133-42.
    PubMed     Text format     Abstract available


  85. ALTER BP, Giri N, Savage SA, Rosenberg PS, et al
    Telomere length in inherited bone marrow failure syndromes.
    Haematologica. 2015;100:49-54.
    PubMed     Text format     Abstract available


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