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Articles published in J Immunol

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Single Articles


    June 2017
  1. LIN CC, Edelson BT
    New Insights into the Role of IL-1beta in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis.
    J Immunol. 2017;198:4553-4560.
    PubMed     Text format     Abstract available


  2. ROY B, Neumann RS, Snir O, Iversen R, et al
    High-Throughput Single-Cell Analysis of B Cell Receptor Usage among Autoantigen-Specific Plasma Cells in Celiac Disease.
    J Immunol. 2017 Jun 9. pii: ji1700169. doi: 10.4049/jimmunol.1700169.
    PubMed     Text format     Abstract available


  3. MORANDI E, Jagessar SA, 't Hart BA, Gran B, et al
    EBV Infection Empowers Human B Cells for Autoimmunity: Role of Autophagy and Relevance to Multiple Sclerosis.
    J Immunol. 2017 Jun 7. pii: ji1700178. doi: 10.4049/jimmunol.1700178.
    PubMed     Text format     Abstract available


  4. TESFAGIORGIS Y, Zhu SL, Jain R, Kerfoot SM, et al
    Activated B Cells Participating in the Anti-Myelin Response Are Excluded from the Inflamed Central Nervous System in a Model of Autoimmunity that Allows for B Cell Recognition of Autoantigen.
    J Immunol. 2017 Jun 5. pii: ji1602042. doi: 10.4049/jimmunol.1602042.
    PubMed     Text format     Abstract available


    May 2017
  5. MATSUMOTO N, Kon S, Nakatsuru T, Miyashita T, et al
    A Novel alpha9 Integrin Ligand, XCL1/Lymphotactin, Is Involved in the Development of Murine Models of Autoimmune Diseases.
    J Immunol. 2017 May 26. pii: 1601329. doi: 10.4049/jimmunol.1601329.
    PubMed     Text format     Abstract available


  6. KLEMENTOWICZ JE, Mahne AE, Spence A, Nguyen V, et al
    Cutting Edge: Origins, Recruitment, and Regulation of CD11c+ Cells in Inflamed Islets of Autoimmune Diabetes Mice.
    J Immunol. 2017 May 26. pii: 1601062. doi: 10.4049/jimmunol.1601062.
    PubMed     Text format     Abstract available


  7. SCHULDT NJ, Auger JL, Spanier JA, Martinov T, et al
    Cutting Edge: Dual TCRalpha Expression Poses an Autoimmune Hazard by Limiting Regulatory T Cell Generation.
    J Immunol. 2017 May 24. pii: 1700406. doi: 10.4049/jimmunol.1700406.
    PubMed     Text format     Abstract available


  8. QIN C, Zhou J, Gao Y, Lai W, et al
    Critical Role of P2Y12 Receptor in Regulation of Th17 Differentiation and Experimental Autoimmune Encephalomyelitis Pathogenesis.
    J Immunol. 2017 May 17. pii: 1601549. doi: 10.4049/jimmunol.1601549.
    PubMed     Text format     Abstract available


  9. GLATIGNY S, Wagner CA, Bettelli E
    Correction: Cutting Edge: Integrin alpha4 Is Required for Regulatory B Cell Control of Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2017;198:3756.
    PubMed     Text format    


  10. BEN-NUN A, Wekerle H, Cohen IR
    Pillars Article: The Rapid Isolation of Clonable Antigen-specific T Lymphocyte Lines Capable of Mediating Autoimmune Encephalomyelitis. Eur J Immunol. 1981.11: 195-199.
    J Immunol. 2017;198:3384-3388.
    PubMed     Text format    


  11. HOHLFELD R, Steinman L
    T Cell-Transfer Experimental Autoimmune Encephalomyelitis: Pillar of Multiple Sclerosis and Autoimmunity.
    J Immunol. 2017;198:3381-3383.
    PubMed     Text format    


  12. GARCIA BL, Skaff DA, Chatterjee A, Hanning A, et al
    Identification of C3b-Binding Small-Molecule Complement Inhibitors Using Cheminformatics.
    J Immunol. 2017;198:3705-3718.
    PubMed     Text format     Abstract available


    April 2017
  13. KATSUYAMA E, Yan M, Watanabe KS, Matsushima S, et al
    Downregulation of miR-200a-3p, Targeting CtBP2, Is Involved in the Hypoproduction of IL-2 in Systemic Lupus Erythematosus-Derived T Cells.
    J Immunol. 2017 Apr 24. pii: 1601705. doi: 10.4049/jimmunol.1601705.
    PubMed     Text format     Abstract available


  14. ROTHE T, Ipseiz N, Faas M, Lang S, et al
    The Nuclear Receptor Nr4a1 Acts as a Microglia Rheostat and Serves as a Therapeutic Target in Autoimmune-Driven Central Nervous System Inflammation.
    J Immunol. 2017 Apr 14. pii: 1600638. doi: 10.4049/jimmunol.1600638.
    PubMed     Text format     Abstract available


  15. MELIS D, Carbone F, Minopoli G, La Rocca C, et al
    Cutting Edge: Increased Autoimmunity Risk in Glycogen Storage Disease Type 1b Is Associated with a Reduced Engagement of Glycolysis in T Cells and an Impaired Regulatory T Cell Function.
    J Immunol. 2017 Apr 7. pii: 1601946. doi: 10.4049/jimmunol.1601946.
    PubMed     Text format     Abstract available


  16. WATANABE T, Yamashita K, Arai Y, Minaga K, et al
    Chronic Fibro-Inflammatory Responses in Autoimmune Pancreatitis Depend on IFN-alpha and IL-33 Produced by Plasmacytoid Dendritic Cells.
    J Immunol. 2017 Apr 3. pii: 1700060. doi: 10.4049/jimmunol.1700060.
    PubMed     Text format     Abstract available


    March 2017
  17. RUS V, Nguyen V, Tatomir A, Lees JR, et al
    RGC-32 Promotes Th17 Cell Differentiation and Enhances Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2017 Mar 29. pii: 1602158. doi: 10.4049/jimmunol.1602158.
    PubMed     Text format     Abstract available


  18. LAGARRIGUE F, Gertler FB, Ginsberg MH, Cantor JM, et al
    Cutting Edge: Loss of T Cell RIAM Precludes Conjugate Formation with APC and Prevents Immune-Mediated Diabetes.
    J Immunol. 2017 Mar 27. pii: 1601743. doi: 10.4049/jimmunol.1601743.
    PubMed     Text format     Abstract available


  19. YU A, Dee MJ, Adeegbe D, Dwyer CJ, et al
    The Lower Limit of Regulatory CD4+ Foxp3+ TCRbeta Repertoire Diversity Required To Control Autoimmunity.
    J Immunol. 2017 Mar 6. pii: 1601966. doi: 10.4049/jimmunol.1601966.
    PubMed     Text format     Abstract available


  20. WU Q, Wang Q, Mao G, Dowling CA, et al
    Dimethyl Fumarate Selectively Reduces Memory T Cells and Shifts the Balance between Th1/Th17 and Th2 in Multiple Sclerosis Patients.
    J Immunol. 2017 Mar 3. pii: 1601532. doi: 10.4049/jimmunol.1601532.
    PubMed     Text format     Abstract available


    February 2017
  21. LEE SY, Moon SJ, Kim EK, Seo HB, et al
    Metformin Suppresses Systemic Autoimmunity in Roquinsan/san Mice through Inhibiting B Cell Differentiation into Plasma Cells via Regulation of AMPK/mTOR/STAT3.
    J Immunol. 2017 Feb 27. pii: 1403088. doi: 10.4049/jimmunol.1403088.
    PubMed     Text format     Abstract available


  22. KANG S, Fedoriw Y, Brenneman EK, Truong YK, et al
    BAFF Induces Tertiary Lymphoid Structures and Positions T Cells within the Glomeruli during Lupus Nephritis.
    J Immunol. 2017 Feb 24. pii: 1600281. doi: 10.4049/jimmunol.1600281.
    PubMed     Text format     Abstract available


  23. LIU R, Ma X, Chen L, Yang Y, et al
    MicroRNA-15b Suppresses Th17 Differentiation and Is Associated with Pathogenesis of Multiple Sclerosis by Targeting O-GlcNAc Transferase.
    J Immunol. 2017 Feb 22. pii: 1601727. doi: 10.4049/jimmunol.1601727.
    PubMed     Text format     Abstract available


  24. ZHOU Y, Chen H, Liu L, Yu X, et al
    CD74 Deficiency Mitigates Systemic Lupus Erythematosus-like Autoimmunity and Pathological Findings in Mice.
    J Immunol. 2017 Feb 20. pii: 1600028. doi: 10.4049/jimmunol.1600028.
    PubMed     Text format     Abstract available


  25. SUNG SJ, Ge Y, Dai C, Wang H, et al
    Dependence of Glomerulonephritis Induction on Novel Intraglomerular Alternatively Activated Bone Marrow-Derived Macrophages and Mac-1 and PD-L1 in Lupus-Prone NZM2328 Mice.
    J Immunol. 2017 Feb 20. pii: 1601565. doi: 10.4049/jimmunol.1601565.
    PubMed     Text format     Abstract available


  26. SHIRANI A, Stuve O
    Natalizumab for Multiple Sclerosis: A Case in Point for the Impact of Translational Neuroimmunology.
    J Immunol. 2017;198:1381-1386.
    PubMed     Text format     Abstract available


  27. BENAGIANO M, Gerosa M, Romagnoli J, Mahler M, et al
    beta2 Glycoprotein I Recognition Drives Th1 Inflammation in Atherosclerotic Plaques of Patients with Primary Antiphospholipid Syndrome.
    J Immunol. 2017 Feb 13. pii: 1600305. doi: 10.4049/jimmunol.1600305.
    PubMed     Text format     Abstract available


  28. BETTENCOURT IA, Powell JD
    Targeting Metabolism as a Novel Therapeutic Approach to Autoimmunity, Inflammation, and Transplantation.
    J Immunol. 2017;198:999-1005.
    PubMed     Text format     Abstract available


    January 2017
  29. NASKAR D, Teng F, Felix KM, Bradley CP, et al
    Synthetic Retinoid AM80 Ameliorates Lung and Arthritic Autoimmune Responses by Inhibiting T Follicular Helper and Th17 Cell Responses.
    J Immunol. 2017 Jan 27. pii: 1601776. doi: 10.4049/jimmunol.1601776.
    PubMed     Text format     Abstract available


  30. NEGROTTO L, Correale J
    Amino Acid Catabolism in Multiple Sclerosis Affects Immune Homeostasis.
    J Immunol. 2017 Jan 27. pii: 1601139. doi: 10.4049/jimmunol.1601139.
    PubMed     Text format     Abstract available


  31. ZHOU Y, Chen H, Liu L, Yu X, et al
    Cathepsin K Deficiency Ameliorates Systemic Lupus Erythematosus-like Manifestations in Faslpr Mice.
    J Immunol. 2017 Jan 16. pii: 1501145. doi: 10.4049/jimmunol.1501145.
    PubMed     Text format     Abstract available


  32. LIANG D, Zuo A, Zhao R, Shao H, et al
    Correction: Regulation of Adenosine Deaminase on Induced Mouse Experimental Autoimmune Uveitis.
    J Immunol. 2017;198:973.
    PubMed     Text format    


  33. COLPITTS SL, Kasper LH
    Influence of the Gut Microbiome on Autoimmunity in the Central Nervous System.
    J Immunol. 2017;198:596-604.
    PubMed     Text format     Abstract available


  34. WEBB LM, Amici SA, Jablonski KA, Savardekar H, et al
    PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2017 Jan 13. pii: 1601702. doi: 10.4049/jimmunol.1601702.
    PubMed     Text format     Abstract available


  35. VANDER HEIDEN JA, Stathopoulos P, Zhou JQ, Chen L, et al
    Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing.
    J Immunol. 2017 Jan 13. pii: 1601415. doi: 10.4049/jimmunol.1601415.
    PubMed     Text format     Abstract available


  36. LIANG D, Nian H, Shao H, Kaplan HJ, et al
    Functional Conversion and Dominance of gammadelta T Subset in Mouse Experimental Autoimmune Uveitis.
    J Immunol. 2017 Jan 9. pii: 1601510. doi: 10.4049/jimmunol.1601510.
    PubMed     Text format     Abstract available


    December 2016
  37. WEINDEL CG, Richey LJ, Mehta AJ, Shah M, et al
    Autophagy in Dendritic Cells and B Cells Is Critical for the Inflammatory State of TLR7-Mediated Autoimmunity.
    J Immunol. 2016 Dec 28. pii: 1601307. doi: 10.4049/jimmunol.1601307.
    PubMed     Text format     Abstract available


  38. RAPOPORT B, Banuelos B, Aliesky HA, Hartwig Trier N, et al
    Critical Differences between Induced and Spontaneous Mouse Models of Graves' Disease with Implications for Antigen-Specific Immunotherapy in Humans.
    J Immunol. 2016;197:4560-4568.
    PubMed     Text format     Abstract available


  39. LI R, Rezk A, Ghadiri M, Luessi F, et al
    Dimethyl Fumarate Treatment Mediates an Anti-Inflammatory Shift in B Cell Subsets of Patients with Multiple Sclerosis.
    J Immunol. 2016 Dec 14. pii: 1601649.
    PubMed     Text format     Abstract available


  40. ONG LT, Tan HF, Feng C, Qu J, et al
    The Systemic Lupus Erythematosus-Associated Single Nucleotide Polymorphism rs1143678 in Integrin alphaM Cytoplasmic Tail Generates a 14-3-3zeta Binding Site That Is Proinflammatory.
    J Immunol. 2016 Dec 14. pii: 1601447.
    PubMed     Text format     Abstract available


  41. HUANG J, Yuan Q, Zhu H, Yin L, et al
    IL-17C/IL-17RE Augments T Cell Function in Autoimmune Hepatitis.
    J Immunol. 2016 Dec 12. pii: 1600977.
    PubMed     Text format     Abstract available


    November 2016
  42. ULIVIERI C, Savino MT, Luccarini I, Fanigliulo E, et al
    Correction: The Adaptor Protein Rai/ShcC Promotes Astrocyte-Dependent Inflammation during Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2016;197:4178.
    PubMed     Text format    


  43. LOPEZ DE LAPUENTE A, Feliu A, Ugidos N, Mecha M, et al
    Correction: Novel Insights into the Multiple Sclerosis Risk Gene ANKRD55.
    J Immunol. 2016;197:4177.
    PubMed     Text format    


  44. CLAES N, Fraussen J, Vanheusden M, Hellings N, et al
    Age-Associated B Cells with Proinflammatory Characteristics Are Expanded in a Proportion of Multiple Sclerosis Patients.
    J Immunol. 2016 Nov 11. pii: 1502448.
    PubMed     Text format     Abstract available


  45. NANDA SK, Lopez-Pelaez M, Arthur JS, Marchesi F, et al
    Suppression of IRAK1 or IRAK4 Catalytic Activity, but Not Type 1 IFN Signaling, Prevents Lupus Nephritis in Mice Expressing a Ubiquitin Binding-Defective Mutant of ABIN1.
    J Immunol. 2016 Nov 2. pii: 1600788.
    PubMed     Text format     Abstract available


    October 2016
  46. WU J, Carlock C, Ross A, Shim J, et al
    CD8alphaalpha+MHC Class II+ Cell with the Capacity To Terminate Autoimmune Inflammation Is a Novel Antigen-Presenting NK-like Cell in Rats.
    J Immunol. 2016 Oct 31. pii: 1601207.
    PubMed     Text format     Abstract available


  47. CHEN D, Ireland SJ, Remington G, Alvarez E, et al
    CD40-Mediated NF-kappaB Activation in B Cells Is Increased in Multiple Sclerosis and Modulated by Therapeutics.
    J Immunol. 2016 Oct 26. pii: 1600782.
    PubMed     Text format     Abstract available


  48. DING Y, Han R, Jiang W, Xiao J, et al
    Programmed Death Ligand 1 Plays a Neuroprotective Role in Experimental Autoimmune Neuritis by Controlling Peripheral Nervous System Inflammation of Rats.
    J Immunol. 2016 Oct 17. pii: 1601083.
    PubMed     Text format     Abstract available


  49. LAM T, Kulp DV, Wang R, Lou Z, et al
    Small Molecule Inhibition of Rab7 Impairs B Cell Class Switching and Plasma Cell Survival To Dampen the Autoantibody Response in Murine Lupus.
    J Immunol. 2016 Oct 14. pii: 1601427.
    PubMed     Text format     Abstract available


  50. HAHN JN, Kaushik DK, Mishra MK, Wang J, et al
    Impact of Minocycline on Extracellular Matrix Metalloproteinase Inducer, a Factor Implicated in Multiple Sclerosis Immunopathogenesis.
    J Immunol. 2016 Oct 12. pii: 1600436.
    PubMed     Text format     Abstract available


    September 2016
  51. SUBBARAYAL B, Chauhan SK, Di Zazzo A, Dana R, et al
    IL-17 Augments B Cell Activation in Ocular Surface Autoimmunity.
    J Immunol. 2016 Sep 21. pii: 1502641.
    PubMed     Text format     Abstract available


  52. ADAMS AB, Ford ML, Larsen CP
    Costimulation Blockade in Autoimmunity and Transplantation: The CD28 Pathway.
    J Immunol. 2016;197:2045-50.
    PubMed     Text format     Abstract available


  53. WANG D, Ghosh D, Islam SM, Moorman CD, et al
    IFN-beta Facilitates Neuroantigen-Dependent Induction of CD25+ FOXP3+ Regulatory T Cells That Suppress Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2016 Sep 12. pii: 1500411.
    PubMed     Text format     Abstract available


    August 2016
  54. MCARDEL SL, Brown DR, Sobel RA, Sharpe AH, et al
    Anti-CD48 Monoclonal Antibody Attenuates Experimental Autoimmune Encephalomyelitis by Limiting the Number of Pathogenic CD4+ T Cells.
    J Immunol. 2016 Aug 31. pii: 1600706.
    PubMed     Text format     Abstract available


  55. DUHLIN A, Chen Y, Wermeling F, Sedimbi SK, et al
    Selective Memory to Apoptotic Cell-Derived Self-Antigens with Implications for Systemic Lupus Erythematosus Development.
    J Immunol. 2016 Aug 24. pii: 1401129.
    PubMed     Text format     Abstract available


  56. AGGELAKOPOULOU M, Kourepini E, Paschalidis N, Simoes DC, et al
    ERbeta-Dependent Direct Suppression of Human and Murine Th17 Cells and Treatment of Established Central Nervous System Autoimmunity by a Neurosteroid.
    J Immunol. 2016 Aug 22. pii: 1601038.
    PubMed     Text format     Abstract available


  57. ZHANG CJ, Gong Y, Zhu W, Qi Y, et al
    Augmentation of Circulating Follicular Helper T Cells and Their Impact on Autoreactive B Cells in Myasthenia Gravis.
    J Immunol. 2016 Aug 19. pii: 1500725.
    PubMed     Text format     Abstract available


  58. DOEDENS JR, Jones WD, Hill K, Mason MJ, et al
    Blood-Borne RNA Correlates with Disease Activity and IFN-Stimulated Gene Expression in Systemic Lupus Erythematosus.
    J Immunol. 2016 Aug 17. pii: 1601142.
    PubMed     Text format     Abstract available


  59. MIYAGAWA F, Tagaya Y, Ozato K, Asada H, et al
    Essential Requirement for IFN Regulatory Factor 7 in Autoantibody Production but Not Development of Nephritis in Murine Lupus.
    J Immunol. 2016 Aug 15. pii: 1502445.
    PubMed     Text format     Abstract available


  60. KAYES TD, Weisman GA, Camden JM, Woods LT, et al
    New Murine Model of Early Onset Autoimmune Thyroid Disease/Hypothyroidism and Autoimmune Exocrinopathy of the Salivary Gland.
    J Immunol. 2016 Aug 12. pii: 1600133.
    PubMed     Text format     Abstract available


  61. GIL-FARINA I, Di Scala M, Salido E, Lopez-Franco E, et al
    Transient Expression of Transgenic IL-12 in Mouse Liver Triggers Unremitting Inflammation Mimicking Human Autoimmune Hepatitis.
    J Immunol. 2016 Aug 10. pii: 1600228.
    PubMed     Text format     Abstract available


  62. PESCHKE K, Achleitner M, Frenzel K, Gerbaulet A, et al
    Loss of Trex1 in Dendritic Cells Is Sufficient To Trigger Systemic Autoimmunity.
    J Immunol. 2016 Aug 10. pii: 1600722.
    PubMed     Text format     Abstract available


  63. ANSTADT EJ, Fujiwara M, Wasko N, Nichols F, et al
    TLR Tolerance as a Treatment for Central Nervous System Autoimmunity.
    J Immunol. 2016 Aug 8. pii: 1600876.
    PubMed     Text format     Abstract available


    July 2016
  64. SESTER DP, Stacey KJ
    Correction: Response to Comment on "Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice".
    J Immunol. 2016;197:676.
    PubMed     Text format    


  65. CHO MJ, Ellebrecht CT, Hammers CM, Mukherjee EM, et al
    Determinants of VH1-46 Cross-Reactivity to Pemphigus Vulgaris Autoantigen Desmoglein 3 and Rotavirus Antigen VP6.
    J Immunol. 2016 Jul 11. pii: 1600567.
    PubMed     Text format     Abstract available


    June 2016
  66. CARE MA, Stephenson SJ, Barnes NA, Fan I, et al
    Network Analysis Identifies Proinflammatory Plasma Cell Polarization for Secretion of ISG15 in Human Autoimmunity.
    J Immunol. 2016 Jun 29. pii: 1600624.
    PubMed     Text format     Abstract available


  67. MANGALAM AK, Rattan R, Suhail H, Singh J, et al
    AMP-Activated Protein Kinase Suppresses Autoimmune Central Nervous System Disease by Regulating M1-Type Macrophage-Th17 Axis.
    J Immunol. 2016 Jun 27. pii: 1501549.
    PubMed     Text format     Abstract available


  68. HANSEN CH, Yurkovetskiy LA, Chervonsky AV
    Cutting Edge: Commensal Microbiota Has Disparate Effects on Manifestations of Polyglandular Autoimmune Inflammation.
    J Immunol. 2016 Jun 20. pii: 1502465.
    PubMed     Text format     Abstract available


  69. SU P, Chen S, Zheng YH, Zhou HY, et al
    Novel Function of Extracellular Matrix Protein 1 in Suppressing Th17 Cell Development in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2016 Jun 17. pii: 1502457.
    PubMed     Text format     Abstract available


  70. ULIVIERI C, Savino MT, Luccarini I, Fanigliulo E, et al
    The Adaptor Protein Rai/ShcC Promotes Astrocyte-Dependent Inflammation during Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2016 Jun 10. pii: 1502063.
    PubMed     Text format     Abstract available


  71. SOOD S, Brownlie RJ, Garcia C, Cowan G, et al
    Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice.
    J Immunol. 2016 Jun 10. pii: 1502656.
    PubMed     Text format     Abstract available


  72. FERRETTI A, Fortwendel JR, Gebb SA, Barrington RA, et al
    Autoantibody-Mediated Pulmonary Alveolar Proteinosis in Rasgrp1-Deficient Mice.
    J Immunol. 2016 Jun 8. pii: 1502248.
    PubMed     Text format     Abstract available


  73. KREBS CF, Turner JE, Paust HJ, Kapffer S, et al
    Plasticity of Th17 Cells in Autoimmune Kidney Diseases.
    J Immunol. 2016 Jun 6. pii: 1501831.
    PubMed     Text format     Abstract available


  74. HARAKAL J, Rival C, Qiao H, Tung KS, et al
    Regulatory T Cells Control Th2-Dominant Murine Autoimmune Gastritis.
    J Immunol. 2016 Jun 3. pii: 1502344.
    PubMed     Text format     Abstract available


    May 2016
  75. CORNETH OB, de Bruijn MJ, Rip J, Asmawidjaja PS, et al
    Enhanced Expression of Bruton's Tyrosine Kinase in B Cells Drives Systemic Autoimmunity by Disrupting T Cell Homeostasis.
    J Immunol. 2016 May 25. pii: 1600208.
    PubMed     Text format     Abstract available


  76. HUARTE E, Jun S, Rynda-Apple A, Golden S, et al
    Regulatory T Cell Dysfunction Acquiesces to BTLA+ Regulatory B Cells Subsequent to Oral Intervention in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2016 May 18. pii: 1501973.
    PubMed     Text format     Abstract available


  77. CHIU S, Fernandez R, Subramanian V, Sun H, et al
    Lung Injury Combined with Loss of Regulatory T Cells Leads to De Novo Lung-Restricted Autoimmunity.
    J Immunol. 2016 May 18. pii: 1502539.
    PubMed     Text format     Abstract available


  78. SMITH C, Buhlmann JE, Wang X, Bartlett A, et al
    CD275-Independent IL-17-Producing T Follicular Helper-like Cells in Lymphopenic Autoimmune-Prone Mice.
    J Immunol. 2016 May 16. pii: 1402193.
    PubMed     Text format     Abstract available


  79. ARTERBERY AS, Osafo-Addo A, Avitzur Y, Ciarleglio M, et al
    Production of Proinflammatory Cytokines by Monocytes in Liver-Transplanted Recipients with De Novo Autoimmune Hepatitis Is Enhanced and Induces TH1-like Regulatory T Cells.
    J Immunol. 2016;196:4040-51.
    PubMed     Text format     Abstract available


  80. AGGELAKOPOULOU M, Kourepini E, Paschalidis N, Panoutsakopoulou V, et al
    ERbeta in CD4+ T Cells Is Crucial for Ligand-Mediated Suppression of Central Nervous System Autoimmunity.
    J Immunol. 2016 May 13. pii: 1600246.
    PubMed     Text format     Abstract available


  81. KARAMPETSOU MP, Comte D, Kis-Toth K, Terhorst C, et al
    Decreased SAP Expression in T Cells from Patients with Systemic Lupus Erythematosus Contributes to Early Signaling Abnormalities and Reduced IL-2 Production.
    J Immunol. 2016 May 11. pii: 1501523.
    PubMed     Text format     Abstract available


  82. ZHAO Y, Nguyen P, Ma J, Wu T, et al
    Preferential Use of Public TCR during Autoimmune Encephalomyelitis.
    J Immunol. 2016 May 11. pii: 1501029.
    PubMed     Text format     Abstract available


  83. LOPEZ DE LAPUENTE A, Feliu A, Ugidos N, Mecha M, et al
    Novel Insights into the Multiple Sclerosis Risk Gene ANKRD55.
    J Immunol. 2016 May 4. pii: 1501205.
    PubMed     Text format     Abstract available


    April 2016
  84. MERLO LM, DuHadaway JB, Grabler S, Prendergast GC, et al
    IDO2 Modulates T Cell-Dependent Autoimmune Responses through a B Cell-Intrinsic Mechanism.
    J Immunol. 2016 Apr 25. pii: 1600141.
    PubMed     Text format     Abstract available


  85. HEALY LM, Perron G, Won SY, Michell-Robinson MA, et al
    MerTK Is a Functional Regulator of Myelin Phagocytosis by Human Myeloid Cells.
    J Immunol. 2016;196:3375-84.
    PubMed     Text format     Abstract available


  86. VELASQUEZ S, Malik S, Lutz SE, Scemes E, et al
    Pannexin1 Channels Are Required for Chemokine-Mediated Migration of CD4+ T Lymphocytes: Role in Inflammation and Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2016 Apr 13. pii: 1502440.
    PubMed     Text format     Abstract available


  87. KANG S, Rogers JL, Monteith AJ, Jiang C, et al
    Apoptotic Debris Accumulates on Hematopoietic Cells and Promotes Disease in Murine and Human Systemic Lupus Erythematosus.
    J Immunol. 2016 Apr 8. pii: 1500418.
    PubMed     Text format     Abstract available


  88. SHIMOJIMA C, Takeuchi H, Jin S, Parajuli B, et al
    Conditioned Medium from the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2016 Apr 6. pii: 1501457.
    PubMed     Text format     Abstract available


    March 2016
  89. JACOBS HM, Thouvenel CD, Leach S, Arkatkar T, et al
    Cutting Edge: BAFF Promotes Autoantibody Production via TACI-Dependent Activation of Transitional B Cells.
    J Immunol. 2016 Mar 28. pii: 1600017.
    PubMed     Text format     Abstract available


  90. GLATIGNY S, Wagner CA, Bettelli E
    Cutting Edge: Integrin alpha4 Is Required for Regulatory B Cell Control of Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2016 Mar 25. pii: 1502614.
    PubMed     Text format     Abstract available


  91. VAN LUMMEL M, van Veelen PA, de Ru AH, Janssen GM, et al
    Dendritic Cells Guide Islet Autoimmunity through a Restricted and Uniquely Processed Peptidome Presented by High-Risk HLA-DR.
    J Immunol. 2016 Mar 4. pii: 1501282.
    PubMed     Text format     Abstract available


  92. QIAN Y, Jeong JS, Ye J, Dang B, et al
    Overlapping IgG4 Responses to Self- and Environmental Antigens in Endemic Pemphigus Foliaceus.
    J Immunol. 2016;196:2041-50.
    PubMed     Text format     Abstract available


    February 2016
  93. RADTKE D, Lacher SM, Szumilas N, Sandrock L, et al
    Grb2 Is Important for T Cell Development, Th Cell Differentiation, and Induction of Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2016 Feb 26. pii: 1501764.
    PubMed     Text format     Abstract available


  94. LEE EJ, Brown BR, Vance EE, Snow PE, et al
    Mincle Activation and the Syk/Card9 Signaling Axis Are Central to the Development of Autoimmune Disease of the Eye.
    J Immunol. 2016 Feb 26. pii: 1502355.
    PubMed     Text format     Abstract available


  95. SAKODA Y, Nagai T, Murata S, Mizuno Y, et al
    Pathogenic Function of Herpesvirus Entry Mediator in Experimental Autoimmune Uveitis by Induction of Th1- and Th17-Type T Cell Responses.
    J Immunol. 2016 Feb 24. pii: 1501742.
    PubMed     Text format     Abstract available


  96. RAM R, Mehta M, Nguyen QT, Larma I, et al
    Systematic Evaluation of Genes and Genetic Variants Associated with Type 1 Diabetes Susceptibility.
    J Immunol. 2016 Feb 24. pii: 1502056.
    PubMed     Text format     Abstract available


  97. HETEMAKI I, Jarva H, Kluger N, Baldauf HM, et al
    Anticommensal Responses Are Associated with Regulatory T Cell Defect in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Patients.
    J Immunol. 2016 Feb 22. pii: 1500301.
    PubMed     Text format     Abstract available


  98. CARLUCCI F, Ishaque A, Ling GS, Szajna M, et al
    C1q Modulates the Response to TLR7 Stimulation by Pristane-Primed Macrophages: Implications for Pristane-Induced Lupus.
    J Immunol. 2016;196:1488-94.
    PubMed     Text format     Abstract available


  99. PATHAK S, Kumar KR, Kanta H, Carr-Johnson F, et al
    Fatty Acid Amide Hydrolase Regulates Peripheral B Cell Receptor Revision, Polyreactivity, and B1 Cells in Lupus.
    J Immunol. 2016;196:1507-16.
    PubMed     Text format     Abstract available


  100. WASCHBISCH A, Schroder S, Schraudner D, Sammet L, et al
    Pivotal Role for CD16+ Monocytes in Immune Surveillance of the Central Nervous System.
    J Immunol. 2016;196:1558-67.
    PubMed     Text format     Abstract available


  101. LIANG D, Zuo A, Zhao R, Shao H, et al
    Regulation of Adenosine Deaminase on Induced Mouse Experimental Autoimmune Uveitis.
    J Immunol. 2016 Feb 8. pii: 1502294.
    PubMed     Text format     Abstract available


  102. GUO B, Rothstein TL
    RasGRP1 Is an Essential Signaling Molecule for Development of B1a Cells with Autoantigen Receptors.
    J Immunol. 2016 Feb 5. pii: 1502132.
    PubMed     Text format     Abstract available


  103. THANEI S, Trendelenburg M
    Anti-C1q Autoantibodies from Systemic Lupus Erythematosus Patients Induce a Proinflammatory Phenotype in Macrophages.
    J Immunol. 2016 Feb 1. pii: 1501659.
    PubMed     Text format     Abstract available


  104. VELAZQUEZ F, Grodecki-Pena A, Knapp A, Salvador AM, et al
    CD43 Functions as an E-Selectin Ligand for Th17 Cells In Vitro and Is Required for Rolling on the Vascular Endothelium and Th17 Cell Recruitment during Inflammation In Vivo.
    J Immunol. 2016;196:1305-16.
    PubMed     Text format     Abstract available


    January 2016
  105. CAO Y, Amezquita RA, Kleinstein SH, Stathopoulos P, et al
    Autoreactive T Cells from Patients with Myasthenia Gravis Are Characterized by Elevated IL-17, IFN-gamma, and GM-CSF and Diminished IL-10 Production.
    J Immunol. 2016 Jan 29. pii: 1501339.
    PubMed     Text format     Abstract available


  106. RAHMAN MJ, Rahir G, Dong MB, Zhao Y, et al
    Despite Increased Type 1 IFN, Autoimmune Nonobese Diabetic Mice Display Impaired Dendritic Cell Response to CpG and Decreased Nuclear Localization of IFN-Activated STAT1.
    J Immunol. 2016 Jan 29. pii: 1501239.
    PubMed     Text format     Abstract available


  107. JIANG W, St-Pierre S, Roy P, Morley BJ, et al
    Infiltration of CCR2+Ly6Chigh Proinflammatory Monocytes and Neutrophils into the Central Nervous System Is Modulated by Nicotinic Acetylcholine Receptors in a Model of Multiple Sclerosis.
    J Immunol. 2016 Jan 25. pii: 1501613.
    PubMed     Text format     Abstract available


  108. NGUYEN V, Rus H, Chen C, Rus V, et al
    CTL-Promoting Effects of IL-21 Counteract Murine Lupus in the Parent-->F1 Graft-versus-Host Disease Model.
    J Immunol. 2016 Jan 20. pii: 1501824.
    PubMed     Text format     Abstract available


  109. BLOCK KE, Zheng Z, Dent AL, Kee BL, et al
    Gut Microbiota Regulates K/BxN Autoimmune Arthritis through Follicular Helper T but Not Th17 Cells.
    J Immunol. 2016 Jan 18. pii: 1501904.
    PubMed     Text format     Abstract available


  110. IFERGAN I, Chen S, Zhang B, Miller SD, et al
    Cutting Edge: MicroRNA-223 Regulates Myeloid Dendritic Cell-Driven Th17 Responses in Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2016 Jan 18. pii: 1501965.
    PubMed     Text format     Abstract available


  111. HASAN M, Yan N
    Response to Comment on "Cutting Edge: Inhibiting TBK1 by Compound II Ameliorates Autoimmune Disease in Mice".
    J Immunol. 2016;196:531.
    PubMed     Text format    


  112. BRENNER D, Andersen PM, Ludolph AC, Weishaupt JH, et al
    Comment on "Cutting Edge: Inhibiting TBK1 by Compound II Ameliorates Autoimmune Disease in Mice".
    J Immunol. 2016;196:530-1.
    PubMed     Text format    


  113. WINGER RC, Harp CT, Chiang MY, Sullivan DP, et al
    Cutting Edge: CD99 Is a Novel Therapeutic Target for Control of T Cell-Mediated Central Nervous System Autoimmune Disease.
    J Immunol. 2016 Jan 15. pii: 1501634.
    PubMed     Text format     Abstract available


  114. RADICHEV IA, Maneva-Radicheva LV, Amatya C, Salehi M, et al
    Loss of Peripheral Protection in Pancreatic Islets by Proteolysis-Driven Impairment of VTCN1 (B7-H4) Presentation Is Associated with the Development of Autoimmune Diabetes.
    J Immunol. 2016 Jan 15. pii: 1403251.
    PubMed     Text format     Abstract available


  115. UJIIE H, Shevach EM
    gammadelta T Cells Protect the Liver and Lungs of Mice from Autoimmunity Induced by Scurfy Lymphocytes.
    J Immunol. 2016 Jan 15. pii: 1501774.
    PubMed     Text format     Abstract available


  116. CHEN D, Ireland SJ, Davis LS, Kong X, et al
    Autoreactive CD19+CD20- Plasma Cells Contribute to Disease Severity of Experimental Autoimmune Encephalomyelitis.
    J Immunol. 2016 Jan 13. pii: 1501376.
    PubMed     Text format     Abstract available


  117. HOSOKAWA K, Muranski P, Feng X, Townsley DM, et al
    Memory Stem T Cells in Autoimmune Disease: High Frequency of Circulating CD8+ Memory Stem Cells in Acquired Aplastic Anemia.
    J Immunol. 2016 Jan 13. pii: 1501739.
    PubMed     Text format     Abstract available


  118. BAUM R, Nundel K, Pawaria S, Sharma S, et al
    Synergy between Hematopoietic and Radioresistant Stromal Cells Is Required for Autoimmune Manifestations of DNase II-/-IFNaR-/- Mice.
    J Immunol. 2016 Jan 4. pii: 1502130.
    PubMed     Text format     Abstract available


  119. JANG E, Cho WS, Oh YK, Cho ML, et al
    Splenic Long-Lived Plasma Cells Promote the Development of Follicular Helper T Cells during Autoimmune Responses.
    J Immunol. 2016 Jan 4. pii: 1401059.
    PubMed     Text format     Abstract available


  120. POIRIER N, Chevalier M, Mary C, Hervouet J, et al
    Selective CD28 Antagonist Blunts Memory Immune Responses and Promotes Long-Term Control of Skin Inflammation in Nonhuman Primates.
    J Immunol. 2016;196:274-83.
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  121. LOPES PINHEIRO MA, Kroon J, Hoogenboezem M, Geerts D, et al
    Acid Sphingomyelinase-Derived Ceramide Regulates ICAM-1 Function during T Cell Transmigration across Brain Endothelial Cells.
    J Immunol. 2016;196:72-9.
    PubMed     Text format     Abstract available


  122. SEBASTIAN M, Lopez-Ocasio M, Metidji A, Rieder SA, et al
    Helios Controls a Limited Subset of Regulatory T Cell Functions.
    J Immunol. 2016;196:144-55.
    PubMed     Text format     Abstract available


    December 2015
  123. DONCEL-PEREZ E, Mateos-Hernandez L, Pareja E, Garcia-Forcada A, et al
    Expression of Early Growth Response Gene-2 and Regulated Cytokines Correlates with Recovery from Guillain-Barre Syndrome.
    J Immunol. 2015 Dec 30. pii: 1502100.
    PubMed     Text format     Abstract available


  124. KIELCZEWSKI JL, Horai R, Jittayasothorn Y, Chan CC, et al
    Tertiary Lymphoid Tissue Forms in Retinas of Mice with Spontaneous Autoimmune Uveitis and Has Consequences on Visual Function.
    J Immunol. 2015 Dec 28. pii: 1501570.
    PubMed     Text format     Abstract available


  125. ZHANG X, Olsen HS, Chen S, So E, et al
    Anti-CD20 Antibody with Multimerized Fc Domains: A Novel Strategy To Deplete B Cells and Augment Treatment of Autoimmune Disease.
    J Immunol. 2015 Dec 22. pii: 1501755.
    PubMed     Text format     Abstract available


  126. FINLAY CM, Stefanska AM, Walsh KP, Kelly PJ, et al
    Helminth Products Protect against Autoimmunity via Innate Type 2 Cytokines IL-5 and IL-33, Which Promote Eosinophilia.
    J Immunol. 2015 Dec 16. pii: 1501820.
    PubMed     Text format     Abstract available


  127. KAUFMANN U, Shaw PJ, Kozhaya L, Subramanian R, et al
    Selective ORAI1 Inhibition Ameliorates Autoimmune Central Nervous System Inflammation by Suppressing Effector but Not Regulatory T Cell Function.
    J Immunol. 2015 Dec 16. pii: 1501406.
    PubMed     Text format     Abstract available


  128. WAN CK, He C, Sun L, Egwuagu CE, et al
    Cutting Edge: IL-1 Receptor Signaling is Critical for the Development of Autoimmune Uveitis.
    J Immunol. 2015 Dec 7. pii: 1502080.
    PubMed     Text format     Abstract available


  129. SHERMAN LA
    Using Autoimmunity To Inform Tumor Immunity.
    J Immunol. 2015;195:5091-5.
    PubMed     Text format    


    November 2015
  130. BAKER RL, Bradley B, Wiles TA, Lindsay RS, et al
    Cutting Edge: Nonobese Diabetic Mice Deficient in Chromogranin A Are Protected from Autoimmune Diabetes.
    J Immunol. 2015 Nov 25. pii: 1501190.
    PubMed     Text format     Abstract available


  131. YIN Y, Choi SC, Xu Z, Zeumer L, et al
    Glucose Oxidation Is Critical for CD4+ T Cell Activation in a Mouse Model of Systemic Lupus Erythematosus.
    J Immunol. 2015 Nov 25. pii: 1501537.
    PubMed     Text format     Abstract available


  132. EHRLICH AK, Pennington JM, Wang X, Rohlman D, et al
    Activation of the Aryl Hydrocarbon Receptor by 10-Cl-BBQ Prevents Insulitis and Effector T Cell Development Independently of Foxp3+ Regulatory T Cells in Nonobese Diabetic Mice.
    J Immunol. 2015 Nov 16. pii: 1501789.
    PubMed     Text format     Abstract available


  133. NG D, Maitre B, Cummings D, Lin A, et al
    A Lymphotoxin/Type I IFN Axis Programs CD8+ T Cells To Infiltrate a Self-Tissue and Propagate Immunopathology.
    J Immunol. 2015;195:4650-9.
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  134. LUPAR E, Brack M, Garnier L, Laffont S, et al
    Eomesodermin Expression in CD4+ T Cells Restricts Peripheral Foxp3 Induction.
    J Immunol. 2015;195:4742-52.
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  135. LIAO X, Li S, Settlage RE, Sun S, et al
    Cutting Edge: Plasmacytoid Dendritic Cells in Late-Stage Lupus Mice Defective in Producing IFN-alpha.
    J Immunol. 2015;195:4578-82.
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  136. TALAEI N, Yu T, Manion K, Bremner R, et al
    Identification of the SLAM Adapter Molecule EAT-2 as a Lupus-Susceptibility Gene That Acts through Impaired Negative Regulation of Dendritic Cell Signaling.
    J Immunol. 2015;195:4623-31.
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  137. HUANG Y, Yang Z, Huang C, McGowan J, et al
    gammadelta T Cell-Dependent Regulatory T Cells Prevent the Development of Autoimmune Keratitis.
    J Immunol. 2015 Nov 13. pii: 1501604.
    PubMed     Text format     Abstract available


  138. REUTER E, Weber J, Paterka M, Ploen R, et al
    Role of Sortilin in Models of Autoimmune Neuroinflammation.
    J Immunol. 2015 Nov 13. pii: 1403156.
    PubMed     Text format     Abstract available


  139. REYNOLDS LA, Finlay BB, Maizels RM
    Cohabitation in the Intestine: Interactions among Helminth Parasites, Bacterial Microbiota, and Host Immunity.
    J Immunol. 2015;195:4059-66.
    PubMed     Text format     Abstract available


  140. MOHAN C
    The Long (and Sometimes Endless) Road to Murine Lupus Genes.
    J Immunol. 2015;195:4043-6.
    PubMed     Text format    


  141. HOOD JD, Zarnitsyna VI, Zhu C, Evavold BD, et al
    Regulatory and T Effector Cells Have Overlapping Low to High Ranges in TCR Affinities for Self during Demyelinating Disease.
    J Immunol. 2015;195:4162-70.
    PubMed     Text format     Abstract available


    October 2015
  142. FRASER HI, Howlett S, Clark J, Rainbow DB, et al
    Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice.
    J Immunol. 2015 Oct 5. pii: 1402654.
    PubMed     Text format     Abstract available


  143. BONAMI RH, Thomas JW
    Targeting Anti-Insulin B Cell Receptors Improves Receptor Editing in Type 1 Diabetes-Prone Mice.
    J Immunol. 2015 Oct 2. pii: 1500438.
    PubMed     Text format     Abstract available


    September 2015
  144. HU Y, Peng J, Tai N, Hu C, et al
    Maternal Antibiotic Treatment Protects Offspring from Diabetes Development in Nonobese Diabetic Mice by Generation of Tolerogenic APCs.
    J Immunol. 2015 Sep 23. pii: 1500884.
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  145. SHAO WH, Gamero AM, Zhen Y, Lobue MJ, et al
    Stat1 Regulates Lupus-like Chronic Graft-versus-Host Disease Severity via Interactions with Stat3.
    J Immunol. 2015 Sep 21. pii: 1501353.
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  146. GILES JR, Kashgarian M, Koni PA, Shlomchik MJ, et al
    B Cell-Specific MHC Class II Deletion Reveals Multiple Nonredundant Roles for B Cell Antigen Presentation in Murine Lupus.
    J Immunol. 2015;195:2571-9.
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  147. BRUCK J, Pascolo S, Fuchs K, Kellerer C, et al
    Cholesterol Modification of p40-Specific Small Interfering RNA Enables Therapeutic Targeting of Dendritic Cells.
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    August 2015
  148. MAEDA Y, Seki N, Kataoka H, Takemoto K, et al
    IL-17-Producing Vgamma4+ gammadelta T Cells Require Sphingosine 1-Phosphate Receptor 1 for Their Egress from the Lymph Nodes under Homeostatic and Inflammatory Conditions.
    J Immunol. 2015;195:1408-16.
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  149. SCHAFFERT SA, Loh C, Wang S, Arnold CP, et al
    mir-181a-1/b-1 Modulates Tolerance through Opposing Activities in Selection and Peripheral T Cell Function.
    J Immunol. 2015;195:1470-9.
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  150. GRISHKAN IV, Tosi DM, Bowman MD, Harary M, et al
    Antigenic Stimulation of Kv1.3-Deficient Th Cells Gives Rise to a Population of Foxp3-Independent T Cells with Suppressive Properties.
    J Immunol. 2015;195:1399-407.
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    January 2015
  151. LU S, Zeumer L, Sorensen H, Yang H, et al
    The murine Pbx1-d lupus susceptibility allele accelerates mesenchymal stem cell differentiation and impairs their immunosuppressive function.
    J Immunol. 2015;194:43-55.
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  152. HUSS DJ, Mehta DS, Sharma A, You X, et al
    In vivo maintenance of human regulatory T cells during CD25 blockade.
    J Immunol. 2015;194:84-92.
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