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The Medical Article of the Year 2008:
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78.
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  Chronic Heart Failure

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Articles published in Circ Res

Retrieve available abstracts of 60 articles:
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Single Articles


    June 2008
  1. VINGE LE , Raake PW, Koch WJ
    Gene therapy in heart failure.
    Circ Res. 2008;102:1458-70.
    PubMed     Related articles    Abstract available


  2. LIU D , Gao L, Roy SK, Cornish KG, et al
    The Role of Oxidant Stress on AT1 Receptor Expression in Neurons of Rabbits With Heart Failure and in Cultured Neurons.
    Circ Res. 2008;.
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  3. O'ROURKE B
    The ins and outs of calcium in heart failure.
    Circ Res. 2008;102:1301-3.
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  4. DESANTIAGO J , Ai X, Islam M, Acuna G, et al
    Arrhythmogenic effects of beta2-adrenergic stimulation in the failing heart are attributable to enhanced sarcoplasmic reticulum Ca load.
    Circ Res. 2008;102:1389-97.
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  5. OZDEMIR S , Bito V, Holemans P, Vinet L, et al
    Pharmacological inhibition of na/ca exchange results in increased cellular Ca2+ load attributable to the predominance of forward mode block.
    Circ Res. 2008;102:1398-405.
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    May 2008
  6. FEUERSTEIN GZ
    Cardiac RAGE in sepsis: call TOLL free for anti-RAGE.
    Circ Res. 2008;102:1153-4.
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  7. BRIDGE JH , Savio-Galimberti E
    What are the consequences of phosphorylation and hyperphosphorylation of ryanodine receptors in normal and failing heart?
    Circ Res. 2008;102:995-7.
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  8. ELSHERIF L , Huang MS, Shai SY, Yang Y, et al
    Combined deficiency of dystrophin and beta1 integrin in the cardiac myocyte causes myocardial dysfunction, fibrosis and calcification.
    Circ Res. 2008;102:1109-17.
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    April 2008
  9. PLEGER ST , Harris DM, Shan C, Vinge LE, et al
    Endothelial S100A1 modulates vascular function via nitric oxide.
    Circ Res. 2008;102:786-94.
    PubMed     Related articles    Abstract available


    March 2008
  10. GOURINE A , Bondar SI, Spyer KM, Gourine AV, et al
    Beneficial effect of the central nervous system beta-adrenoceptor blockade on the failing heart.
    Circ Res. 2008;102:633-6.
    PubMed     Related articles    Abstract available


  11. CHAN JY , Takeda M, Briggs LE, Graham ML, et al
    Identification of cardiac-specific myosin light chain kinase.
    Circ Res. 2008;102:571-80.
    PubMed     Related articles    Abstract available


  12. GONZALEZ A , Rota M, Nurzynska D, Misao Y, et al
    Activation of cardiac progenitor cells reverses the failing heart senescent phenotype and prolongs lifespan.
    Circ Res. 2008;102:597-606.
    PubMed     Related articles    Abstract available


    January 2008
  13. BOSSUYT J , Helmstadter K, Wu X, Clements-Jewery H, et al
    Ca2+/Calmodulin-Dependent Protein Kinase II{delta} and Protein Kinase D Overexpression Reinforce the Histone Deacetylase 5 Redistribution in Heart Failure.
    Circ Res. 2008;.
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    November 2007
  14. BANKSTON JR , Kass RS
    Fading sodium channels in failing hearts.
    Circ Res. 2007;101:1073-4.
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  15. LIAO R , Force T
    Not all hypertrophy is created equal.
    Circ Res. 2007;101:1069-72.
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  16. TIMMERS L , Sluijter JP, van Keulen JK, Hoefer IE, et al
    Toll-Like Receptor 4 Mediates Maladaptive Left Ventricular Remodeling and Impairs Cardiac Function Following Myocardial Infarction.
    Circ Res. 2007;.
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    October 2007
  17. SPACH MS
    Mounting evidence that fibrosis generates a major mechanism for atrial fibrillation.
    Circ Res. 2007;101:743-5.
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  18. GUO T , Ai X, Shannon TR, Pogwizd SM, et al
    Intra-sarcoplasmic reticulum free [Ca2+] and buffering in arrhythmogenic failing rabbit heart.
    Circ Res. 2007;101:802-10.
    PubMed     Related articles    Abstract available


    September 2007
  19. SHANG LL , Pfahnl AE, Sanyal S, Jiao Z, et al
    Human Heart Failure Is Associated With Abnormal C-Terminal Splicing Variants in the Cardiac Sodium Channel.
    Circ Res. 2007;.
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  20. HIROTANI S , Zhai P, Tomita H, Galeotti J, et al
    Inhibition of Glycogen Synthase Kinase 3{beta} During Heart Failure Is Protective.
    Circ Res. 2007;.
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    August 2007
  21. BENKUSKY NA , Weber CS, Scherman JA, Farrell EF, et al
    Intact {beta}-Adrenergic Response and Unmodified Progression Toward Heart Failure in Mice With Genetic Ablation of a Major Protein Kinase A Phosphorylation Site in the Cardiac Ryanodine Receptor.
    Circ Res. 2007;.
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  22. TANAKA K , Zlochiver S, Vikstrom KL, Yamazaki M, et al
    The Spatial Distribution of Fibrosis Governs Fibrillation Wave Dynamics in the Posterior Left Atrium During Heart Failure.
    Circ Res. 2007;.
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  23. RAMIREZ-CORREA GA , Murphy AM
    Is phospholamban or troponin I the "prima donna" in beta-adrenergic induced lusitropy?
    Circ Res. 2007;101:326-7.
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  24. KUBA K , Zhang L, Imai Y, Arab S, et al
    Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload.
    Circ Res. 2007;101:e32-42.
    PubMed     Related articles    Abstract available


  25. LEENEN FH
    Brain mechanisms contributing to sympathetic hyperactivity and heart failure.
    Circ Res. 2007;101:221-3.
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  26. SONG L , Yan W, Chen X, Deng CX, et al
    Myocardial smad4 is essential for cardiogenesis in mouse embryos.
    Circ Res. 2007;101:277-85.
    PubMed     Related articles    Abstract available


    July 2007
  27. SOLARO RJ
    Translational medicine with a capital T, troponin T, that is.
    Circ Res. 2007;101:114-5.
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  28. DU CK , Morimoto S, Nishii K, Minakami R, et al
    Knock-in mouse model of dilated cardiomyopathy caused by troponin mutation.
    Circ Res. 2007;101:185-94.
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  29. RAJAN S , Ahmed RP, Jagatheesan G, Petrashevskaya N, et al
    Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity.
    Circ Res. 2007;101:205-14.
    PubMed     Related articles    Abstract available


    June 2007
  30. FENG N , Hoover DB, Paolocci N
    Forever young?: nerve growth factor, sympathetic fibers, and right ventricle pressure overload.
    Circ Res. 2007;100:1670-2.
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  31. KIMURA K , Ieda M, Kanazawa H, Yagi T, et al
    Cardiac sympathetic rejuvenation: a link between nerve function and cardiac hypertrophy.
    Circ Res. 2007;100:1755-64.
    PubMed     Related articles    Abstract available


  32. YU Y , Zhang ZH, Wei SG, Chu Y, et al
    Central Gene Transfer of Interleukin-10 Reduces Hypothalamic Inflammation and Evidence of Heart Failure in Rats After Myocardial Infarction.
    Circ Res. 2007;.
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  33. BELIN RJ , Sumandea MP, Allen EJ, Schoenfelt K, et al
    Augmented Protein Kinase C-{alpha}-Induced Myofilament Protein Phosphorylation Contributes to Myofilament Dysfunction in Experimental Congestive Heart Failure.
    Circ Res. 2007;.
    PubMed     Related articles    Abstract available


    May 2007
  34. HANNIGAN GE , Coles JG, Dedhar S
    Integrin-linked kinase at the heart of cardiac contractility, repair, and disease.
    Circ Res. 2007;100:1408-14.
    PubMed     Related articles    Abstract available


  35. CHENG RK , Asai T, Tang H, Dashoush NH, et al
    Cyclin A2 Induces Cardiac Regeneration After Myocardial Infarction and Prevents Heart Failure.
    Circ Res. 2007;.
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  36. TRAVERSE JH , Chen Y, Hou M, Li Y, et al
    Effect of K+ATP Channel and Adenosine Receptor Blockade During Rest and Exercise in Congestive Heart Failure.
    Circ Res. 2007;.
    PubMed     Related articles    Abstract available


    April 2007
  37. GALVEZ AS , Diwan A, Odley AM, Hahn HS, et al
    Cardiomyocyte degeneration with calpain deficiency reveals a critical role in protein homeostasis.
    Circ Res. 2007;100:1071-8.
    PubMed     Related articles    Abstract available


  38. STICKLAND MK , Miller JD, Smith CA, Dempsey JA, et al
    Carotid Chemoreceptor Modulation of Regional Blood Flow Distribution During Exercise in Health and Chronic Heart Failure.
    Circ Res. 2007;.
    PubMed     Related articles    Abstract available


    March 2007
  39. ASSMUS B , Fischer-Rasokat U, Honold J, Seeger FH, et al
    Transcoronary Transplantation of Functionally Competent BMCs Is Associated With a Decrease in Natriuretic Peptide Serum Levels and Improved Survival of Patients With Chronic Postinfarction Heart Failure. Results of the TOPCARE-CHD Registry.
    Circ Res. 2007;.
    PubMed     Related articles    Abstract available


  40. ZHANG P , Xu X, Hu X, van Deel E, et al
    Inducible Nitric Oxide Synthase Deficiency Protects the Heart From Systolic Overload-Induced Ventricular Hypertrophy and Congestive Heart Failure.
    Circ Res. 2007;.
    PubMed     Related articles    Abstract available


  41. YAN C , Ding B, Shishido T, Woo CH, et al
    Activation of extracellular signal-regulated kinase 5 reduces cardiac apoptosis and dysfunction via inhibition of a phosphodiesterase 3A/inducible cAMP early repressor feedback loop.
    Circ Res. 2007;100:510-9.
    PubMed     Related articles    Abstract available


    February 2007
  42. SIPIDO KR
    CaM or cAMP: linking beta-adrenergic stimulation to 'leaky' RyRs.
    Circ Res. 2007;100:296-8.
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  43. CURRAN J , Hinton MJ, Rios E, Bers DM, et al
    Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase.
    Circ Res. 2007;100:391-8.
    PubMed     Related articles    Abstract available


  44. MERKLE S , Frantz S, Schon MP, Bauersachs J, et al
    A Role for Caspase-1 in Heart Failure.
    Circ Res. 2007;.
    PubMed     Related articles    Abstract available


    January 2007
  45. CARDIN S , Libby E, Pelletier P, Le Bouter S, et al
    Contrasting Gene Expression Profiles in Two Canine Models of Atrial Fibrillation.
    Circ Res. 2007;.
    PubMed     Related articles    Abstract available


    December 2006
  46. WANG X , Robbins J
    Heart failure and protein quality control.
    Circ Res. 2006;99:1315-28.
    PubMed     Related articles    Abstract available


  47. GUO J , Sabri A, Elouardighi H, Rybin V, et al
    Alpha1-adrenergic receptors activate AKT via a Pyk2/PDK-1 pathway that is tonically inhibited by novel protein kinase C isoforms in cardiomyocytes.
    Circ Res. 2006;99:1367-75.
    PubMed     Related articles    Abstract available


  48. VALENCIK ML , Zhang D, Punske B, Hu P, et al
    Integrin activation in the heart: a link between electrical and contractile dysfunction?
    Circ Res. 2006;99:1403-10.
    PubMed     Related articles    Abstract available


  49. SAKAMOTO M , Minamino T, Toko H, Kayama Y, et al
    Upregulation of heat shock transcription factor 1 plays a critical role in adaptive cardiac hypertrophy.
    Circ Res. 2006;99:1411-8.
    PubMed     Related articles    Abstract available


    November 2006
  50. LONDON B
    CaM kinase inhibition: apply directly to the heart?
    Circ Res. 2006;99:1027-8.
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  51. HUBER SA , Feldman AM, Sartini D
    Coxsackievirus B3 induces T regulatory cells, which inhibit cardiomyopathy in tumor necrosis factor-alpha transgenic mice.
    Circ Res. 2006;99:1109-16.
    PubMed     Related articles    Abstract available


    September 2006
  52. LIU D , Gao L, Roy SK, Cornish KG, et al
    Neuronal Angiotensin II Type 1 Receptor Upregulation in Heart Failure. Activation of Activator Protein 1 and Jun N-Terminal Kinase.
    Circ Res. 2006;.
    PubMed     Related articles    Abstract available


  53. KANG YM , Zhang ZH, Johnson RF, Yu Y, et al
    Novel Effect of Mineralocorticoid Receptor Antagonism to Reduce Proinflammatory Cytokines and Hypothalamic Activation in Rats With Ischemia-Induced Heart Failure.
    Circ Res. 2006;.
    PubMed     Related articles    Abstract available


    August 2006
  54. LOWENSTEIN CJ
    Integrin-linked kinase plays a key role in coxsackievirus replication.
    Circ Res. 2006;99:346-7.
    PubMed     Related articles   


    July 2006
  55. KHUCHUA Z , Yue Z, Batts L, Strauss AW, et al
    A zebrafish model of human Barth syndrome reveals the essential role of tafazzin in cardiac development and function.
    Circ Res. 2006;99:201-8.
    PubMed     Related articles    Abstract available


  56. MESSINA E , Giacomello A
    Diabetic cardiomyopathy: a "cardiac stem cell disease" involving p66Shc, an attractive novel molecular target for heart failure therapy.
    Circ Res. 2006;99:1-2.
    PubMed     Related articles   


    June 2006
  57. SINGH G , Kuc RE, Maguire JJ, Fidock M, et al
    Novel Snake Venom Ligand Dendroaspis Natriuretic Peptide Is Selective for Natriuretic Peptide Receptor-A in Human Heart. Downregulation of Natriuretic Peptide Receptor-A in Heart Failure.
    Circ Res. 2006;.
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  58. ROTA M , Lecapitaine N, Hosoda T, Boni A, et al
    Diabetes Promotes Cardiac Stem Cell Aging and Heart Failure, Which Are Prevented by Deletion of the p66shc Gene.
    Circ Res. 2006;.
    PubMed     Related articles    Abstract available


    May 2006
  59. LUNDE PK , Sejersted OM, Thorud HM, Tonnessen T, et al
    Effects of Congestive Heart Failure on Ca2+ Handling in Skeletal Muscle During Fatigue.
    Circ Res. 2006;.
    PubMed     Related articles    Abstract available


    March 2006
  60. DANILCZYK U , Penninger JM
    Angiotensin-converting enzyme II in the heart and the kidney.
    Circ Res. 2006;98:463-71.
    PubMed     Related articles    Abstract available


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