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  Liver Cirrhosis

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Articles published in Gastroenterology

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    July 2017
  1. LENS S, Alvarado E, Marino Z, Londono MC, et al
    Effects of All-oral Anti-viral Therapy on HVPG and Systemic Hemodynamics in Patients with Hepatitis C Virus-associated Cirrhosis.
    Gastroenterology. 2017 Jul 19. pii: S0016-5085(17)35922.
    PubMed     Text format     Abstract available

  2. KING A, Houlihan DD, Kavanagh D, Haldar D, et al
    Sphingosine-1-Phosphate Prevents Egress of Hematopoietic Stem Cells From Liver to Reduce Fibrosis.
    Gastroenterology. 2017;153:233-248.
    PubMed     Text format     Abstract available

  3. KHAMRI W, Abeles RD, Hou TZ, Anderson AE, et al
    Increased Expression of Cytotoxic T-Lymphocyte-Associated Protein 4 by T Cells, Induced by B7 in Sera, Reduces Adaptive Immunity in Patients With Acute Liver Failure.
    Gastroenterology. 2017;153:263-276.
    PubMed     Text format     Abstract available

    June 2017
  4. KANWAL F, Kramer J, Asch SM, Chayanupatkul M, et al
    Risk of Hepatocellular Cancer in HCV Patients Treated with Direct Acting Antiviral Agents.
    Gastroenterology. 2017 Jun 19. pii: S0016-5085(17)35797.
    PubMed     Text format     Abstract available

  5. CANNON MD, Heneghan MA
    Endoscopy in Pregnant Women with Liver Cirrhosis.
    Gastroenterology. 2017 Jun 1. pii: S0016-5085(17)35602.
    PubMed     Text format    

    May 2017
  6. LOFFREDO L, Pastori D, Farcomeni A, Violi F, et al
    Effects of Anticoagulants in Patients With Cirrhosis and Portal Vein Thrombosis: a Systematic Review and Meta-Analysis.
    Gastroenterology. 2017 May 4. pii: S0016-5085(17)35552.
    PubMed     Text format     Abstract available

  7. KHAN MA, Cholankeril G, Howden CW
    Proton Pump Inhibitors and the Possible Development of Hepatic Encephalopathy in Cirrhotic Patients: True Association or Residual Confounding?
    Gastroenterology. 2017 May 4. pii: S0016-5085(17)35404.
    PubMed     Text format    

  8. ASSARAF J, Weiss N, Thabut D
    Proton Pump Inhibitor Administration Triggers Encephalopathy in Cirrhotic Patients by Modulating Blood-Brain Barrier Drug Transport.
    Gastroenterology. 2017 May 4. pii: S0016-5085(17)35403.
    PubMed     Text format    

  9. SINGH S, Muir AJ, Dieterich DT, Falck-Ytter YT, et al
    American Gastroenterological Association Institute Technical Review on the Role of Elastography in Chronic Liver Diseases.
    Gastroenterology. 2017;152:1544-1577.
    PubMed     Text format     Abstract available

  10. LAI KKY, Kweon SM, Chi F, Hwang E, et al
    Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6.
    Gastroenterology. 2017;152:1477-1491.
    PubMed     Text format     Abstract available

    April 2017
  11. AN SY, Jang YJ, Lim HJ, Han J, et al
    Milk Fat Globule-EGF Factor 8, Secreted by Mesenchymal Stem Cells, Protects Against Liver Fibrosis in Mice.
    Gastroenterology. 2017;152:1174-1186.
    PubMed     Text format     Abstract available

    March 2017
  12. JACOBSON IM, Lim JK, Fried MW
    AGA Institute Clinical Practice Update: Care of Patients Who Have Achieved a Sustained Virologic Response (SVR) Following Antiviral Therapy for Chronic Hepatitis C Infection.
    Gastroenterology. 2017 Mar 23. pii: S0016-5085(17)30327.
    PubMed     Text format     Abstract available

    Classification of Portal Vein Thrombosis in Cirrhosis.
    Gastroenterology. 2017 Mar 3. pii: S0016-5085(17)30135.
    PubMed     Text format    

    February 2017
  14. JACOBSON IM, Lawitz E, Kwo PY, Hezode C, et al
    Safety and Efficacy of Elbasvir/Grazoprevir in Patients with Hepatitis C Virus Infection and Compensated Cirrhosis: an Integrated Analysis.
    Gastroenterology. 2017 Feb 10. pii: S0016-5085(17)30150.
    PubMed     Text format     Abstract available

  15. MATSUURA K, Sawai H, Ikeo K, Ogawa S, et al
    Genome-wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection.
    Gastroenterology. 2017 Feb 2. pii: S0016-5085(17)30130.
    PubMed     Text format     Abstract available

  16. RAVI S, Axley P, Jones D, Kodali S, et al
    Unusually High Rates of Hepatocellular Carcinoma After Treatment With Direct-Acting Antiviral Therapy for Hepatitis C Related Cirrhosis.
    Gastroenterology. 2017 Feb 1. pii: S0016-5085(16)35535.
    PubMed     Text format    

  17. PARK CC, Nguyen P, Hernandez C, Bettencourt R, et al
    Magnetic Resonance Elastography vs Transient Elastography in Detection of Fibrosis and Noninvasive Measurement of Steatosis in Patients With Biopsy-Proven Nonalcoholic Fatty Liver Disease.
    Gastroenterology. 2017;152:598-607.
    PubMed     Text format     Abstract available

    January 2017
  18. GOLDBERG D, Ditah IC, Saeian K, Lalehzari M, et al
    Changes in the Prevalence of Hepatitis C Virus Infection, Non-alcoholic Steatohepatitis, and Alcoholic Liver Disease Among Patients with Cirrhosis or Liver Failure on the Waitlist for Liver Transplantation.
    Gastroenterology. 2017 Jan 11. pii: S0016-5085(17)30014.
    PubMed     Text format     Abstract available

    November 2016
  19. SINGAL AG, Tiro JA, Marrero JA, McCallister K, et al
    Mailed Outreach Program Increases Ultrasound Screening of Patients with Cirrhosis for Hepatocellular Carcinoma.
    Gastroenterology. 2016 Nov 5. pii: S0016-5085(16)35321.
    PubMed     Text format     Abstract available

    October 2016
  20. WEERSINK RA, Drenth JP, Borgsteede SD
    Altered Pharmacokinetics of Statins Explain Increased Risk of Rhabdomyolysis in Advanced Cirrhosis.
    Gastroenterology. 2016 Oct 3. pii: S0016-5085(16)35074.
    PubMed     Text format    

  21. LO GH
    Did Statins Really Improve Survival in Cirrhotic Patients With a History of Variceal Bleeding?
    Gastroenterology. 2016 Oct 1. pii: S0016-5085(16)35075.
    PubMed     Text format    

    September 2016
  22. BUREAU C, Thabut D, Oberti F, Dharancy S, et al
    Transjugular Intrahepatic Portosystemic Shunts With Covered Stents Increase Transplant-free Survival of Patients With Cirrhosis and Recurrent Ascites.
    Gastroenterology. 2016 Sep 20. pii: S0016-5085(16)35110.
    PubMed     Text format     Abstract available

  23. NAHON P, Bourcier V, Layese R, Audureau E, et al
    Eradication of Hepatitis C Virus Infection in Patients With Cirrhosis Reduces Risk of Liver and Non-Liver Complications.
    Gastroenterology. 2016 Sep 15. pii: S0016-5085(16)35070.
    PubMed     Text format     Abstract available

  24. TSAI CF, Chen MH, Wang YP, Chu CJ, et al
    Proton Pump Inhibitors Increase Risk for Hepatic Encephalopathy in Patients With Cirrhosis in Population Study.
    Gastroenterology. 2016 Sep 14. pii: S0016-5085(16)35032.
    PubMed     Text format     Abstract available

    August 2016
  25. KALMAN RS, Goldberg DS
    Obeticholic Acid Reduces Bacterial Translocation and Inhibits Intestinal Inflammation in Cirrhotic Rats.
    Gastroenterology. 2016 Aug 28. pii: S0016-5085(16)34977.
    PubMed     Text format    

  26. SARIN SK, Philips CA, Kamath PS, Choudhary A, et al
    Towards a Comprehensive New Classification of Portal Vein Thrombosis in Patients with Cirrhosis: A Commentary.
    Gastroenterology. 2016 Aug 26. pii: S0016-5085(16)34975.
    PubMed     Text format    

  27. TERRAULT NA, Zeuzem S, Di Bisceglie AM, Lim JK, et al
    Effectiveness of Ledipasvir-Sofosbuvir Combination in Patients With Hepatitis C Virus Infection and Factors Associated of Sustained Virologic Response.
    Gastroenterology. 2016 Aug 23. pii: S0016-5085(16)34927.
    PubMed     Text format     Abstract available

    July 2016
  28. GANE E, Poordad F, Wang S, Asatryan A, et al
    High Efficacy of ABT-493 and ABT-530 in Patients with HCV Genotype 1 or 3 Infection and Compensated Cirrhosis.
    Gastroenterology. 2016 Jul 22. pii: S0016-5085(16)34816.
    PubMed     Text format     Abstract available

  29. SHIN JY, Azoulay L, Filion KB
    Statin Use in Patients With Hepatitis C-related Cirrhosis: True Benefit or Immortal Time Bias?
    Gastroenterology. 2016 Jul 1. pii: S0016-5085(16)34434.
    PubMed     Text format    

    June 2016
  30. IOANNOU GN, Beste LA, Chang MF, Green PK, et al
    Effectiveness of Sofosbuvir, Ledipasvir/Sofosbuvir, or Paritaprevir/Ritonavir/Ombitasvir and Dasabuvir Regimens for Treatment of Patients With Hepatitis C in the Veterans Affairs National Healthcare System.
    Gastroenterology. 2016 Jun 4. pii: S0016-5085(16)34575.
    PubMed     Text format     Abstract available

    May 2016
  31. GANE EJ, Schwabe C, Hyland RH, Yang Y, et al
    Efficacy of the Combination of Sofosbuvir, Velpatasvir, and the NS3/4A Protease Inhibitor GS-9857 in Treatment-naive or Previously Treated Patients with HCV Genotype 1 or 3 Infections.
    Gastroenterology. 2016 May 27. pii: S0016-5085(16)34513.
    PubMed     Text format     Abstract available

  32. MANCINA RM, Dongiovanni P, Petta S, Pingitore P, et al
    The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent.
    Gastroenterology. 2016;150:1219-1230.
    PubMed     Text format     Abstract available

    April 2016
    Biliary Cirrhosis Treated With Ursodeoxycholic Acid.
    Gastroenterology. 2016 Apr 29. pii: S0016-5085(16)00363.
    PubMed     Text format    

  34. CALDERONE V, Gallego J, Fernandez-Miranda G, Garcia-Pras E, et al
    Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease.
    Gastroenterology. 2016;150:982-97.
    PubMed     Text format     Abstract available

    March 2016
  35. DI MARCO V, Calvaruso V, Ferraro D, Bavetta MG, et al
    Effects of Viral Eradication in Patients with HCV and Cirrhosis Differ With Stage of Portal Hypertension.
    Gastroenterology. 2016 Mar 31. pii: S0016-5085(16)30049.
    PubMed     Text format     Abstract available

  36. CHIN JL, Chan G, Ryan JD
    Noninvasive Assessment of Liver Fibrosis and Cirrhosis With Ultrasound-based Elastography in Alcohol-related Liver Disease.
    Gastroenterology. 2016 Mar 25. pii: S0016-5085(16)00301.
    PubMed     Text format    

  37. NEPHEW LD, Goldberg DS
    Impact of Anticoagulation on Upper Gastrointestinal Bleeding in Cirrhosis.
    Gastroenterology. 2016 Mar 24. pii: S0016-5085(16)00377.
    PubMed     Text format    

    A new treatment for portal hypertension?
    Gastroenterology. 2016 Mar 23. pii: S0016-5085(16)00368.
    PubMed     Text format    

  39. LASSAILLY G, Caiazzo R, Pattou F, Mathurin P, et al
    Perspectives on Treatment for Nonalcoholic Steatohepatitis.
    Gastroenterology. 2016 Mar 10. pii: S0016-5085(16)00323.
    PubMed     Text format     Abstract available

  40. TAOULI B, Serfaty L
    Magnetic Resonance Imaging/Elastography Is Superior to Transient Elastography for Detection of Liver Fibrosis and Fat in Nonalcoholic Fatty Liver Disease.
    Gastroenterology. 2016;150:553-6.
    PubMed     Text format    

  41. IMAJO K, Kessoku T, Honda Y, Tomeno W, et al
    Magnetic Resonance Imaging More Accurately Classifies Steatosis and Fibrosis in Patients With Nonalcoholic Fatty Liver Disease Than Transient Elastography.
    Gastroenterology. 2016;150:626-637.
    PubMed     Text format     Abstract available

    February 2016
  42. BOYER TD, Sanyal AJ, Wong F, Frederick RT, et al
    Terlipressin plus albumin is more effective than albumin alone in improving renal function in patients with cirrhosis and hepatorenal syndrome type 1.
    Gastroenterology. 2016 Feb 16. pii: S0016-5085(16)00217.
    PubMed     Text format     Abstract available

  43. RATZIU V, Harrison S, Francque S, Bedossa P, et al
    Elafibranor, an Agonist of the Peroxisome Proliferator-activated Receptor-alpha and -delta, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening.
    Gastroenterology. 2016 Feb 10. pii: S0016-5085(16)00140.
    PubMed     Text format     Abstract available

    January 2016
  44. ABRALDES JG, Villanueva C, Aracil C, Turnes J, et al
    Addition of Simvastatin to Standard Therapy for the Prevention of Variceal Rebleeding Does not Reduce Rebleeding but Increases Survival in Patients With Cirrhosis.
    Gastroenterology. 2016 Jan 13. pii: S0016-5085(16)00043.
    PubMed     Text format     Abstract available

  45. HIRSOVA P, Ibrahim SH, Krishnan A, Verma VK, et al
    Lipid-induced Signaling Causes Release of Inflammatory Extracellular Vesicles from Hepatocytes.
    Gastroenterology. 2016 Jan 4. pii: S0016-5085(15)01865.
    PubMed     Text format     Abstract available

    Early Detection of Alcoholic Liver Disease: Are We a Step Closer?
    Gastroenterology. 2016;150:29-31.
    PubMed     Text format    

    November 2015
  47. MU X, Pradere JP, Affo S, Dapito DH, et al
    Epithelial Transforming Growth Factor-beta Signaling Does Not Contribute to Liver Fibrosis but Protects Mice From Cholangiocarcinoma.
    Gastroenterology. 2015 Nov 25. pii: S0016-5085(15)01721.
    PubMed     Text format     Abstract available

    October 2015
  48. WHITE DL, Richardson P, Tayoub N, Davila JA, et al
    The Updated Model: An Adjusted Serum Alpha-Fetoprotein-Based Algorithm for Hepatocellular Carcinoma Detection With Hepatitis C Virus-Related Cirrhosis.
    Gastroenterology. 2015 Oct 28. pii: S0016-5085(15)01435.
    PubMed     Text format    

  49. MOHANTY A, Tate J, Garcia-Tsao G
    Statins are Associated with a Decreased Risk of Decompensation and Death in Veterans with Hepatitis C-related Compensated Cirrhosis.
    Gastroenterology. 2015 Oct 17. pii: S0016-5085(15)01476.
    PubMed     Text format     Abstract available

  50. THIELE M, Detlefsen S, Sevelsted Moller L, Madsen BS, et al
    Transient and 2-dimensional Shear-Wave Elastography provide comparable assessment of Alcoholic Liver Fibrosis and Cirrhosis.
    Gastroenterology. 2015 Oct 1. pii: S0016-5085(15)01426.
    PubMed     Text format     Abstract available

  51. KOO JH, Lee HJ, Kim W, Kim SG, et al
    Endoplasmic Reticulum Stress in Hepatic Stellate Cells Promotes Liver Fibrosis via PERK-mediated Degradation of HNRNPA1 and Upregulation of SMAD2.
    Gastroenterology. 2015 Oct 1. pii: S0016-5085(15)01425.
    PubMed     Text format     Abstract available

    September 2015
  52. BAJAJ JS
    Diagnosing Minimal Hepatic Encephalopathy: From the Ivory Tower to the Real World.
    Gastroenterology. 2015 Sep 25. pii: S0016-5085(15)01384.
    PubMed     Text format    

  53. BEUERS U, Gershwin ME, Gish RG, Invernizzi P, et al
    Changing Nomenclature for PBC: From 'Cirrhosis' to 'Cholangitis'.
    Gastroenterology. 2015 Sep 15. pii: S0016-5085(15)01199.
    PubMed     Text format    

  54. GARCIA-PAGAN JC, Patch D
    Trials and Tribulations: The Prevention of Variceal Rebleeding.
    Gastroenterology. 2015;149:528-31.
    PubMed     Text format    

  55. DU PLESSIS J, van Pelt J, Korf H, Mathieu C, et al
    Association of Adipose Tissue Inflammation With Histologic Severity of Nonalcoholic Fatty Liver Disease.
    Gastroenterology. 2015;149:635-48.
    PubMed     Text format     Abstract available

  56. XANTHAKOS SA, Jenkins TM, Kleiner DE, Boyce TW, et al
    High Prevalence of Nonalcoholic Fatty Liver Disease in Adolescents Undergoing Bariatric Surgery.
    Gastroenterology. 2015;149:623-34.
    PubMed     Text format     Abstract available

    August 2015
  57. AMPUERO J, Simon M, Montoliu C, Jover R, et al
    Minimal Hepatic Encephalopathy and Critical Flicker Frequency are Associated With Survival of Patients With Cirrhosis.
    Gastroenterology. 2015 Aug 20. pii: S0016-5085(15)01176.
    PubMed     Text format     Abstract available

  58. LOOMBA R, Schork N, Chen CH, Bettencourt R, et al
    Heritability of Hepatic Fibrosis and Steatosis Based on a Prospective Twin Study.
    Gastroenterology. 2015 Aug 20. pii: S0016-5085(15)01179.
    PubMed     Text format     Abstract available

  59. LAMMERS WJ, Hirschfield GM, Corpechot C, Nevens F, et al
    Development and Validation of a Scoring System to Predict Outcomes of Patients With Primary Biliary Cirrhosis Receiving Ursodeoxycholic Acid Therapy.
    Gastroenterology. 2015 Aug 7. pii: S0016-5085(15)01094.
    PubMed     Text format     Abstract available

  60. BESTE LA, Leipertz SL, Green PK, Dominitz JA, et al
    Trends in the burden of cirrhosis and hepatocellular carcinoma by underlying liver disease in US Veterans from 2001-2013.
    Gastroenterology. 2015 Aug 5. pii: S0016-5085(15)01088.
    PubMed     Text format     Abstract available

  61. FOSTER GR, Pianko S, Brown A, Forton D, et al
    Efficacy of Sofosbuvir Plus Ribavirin With or Without Peginterferon-alfa in Patients With HCV Genotype 3 Infection and Treatment-Experienced Patients with Cirrhosis and HCV Genotype 2 Infection.
    Gastroenterology. 2015 Aug 3. pii: S0016-5085(15)01069.
    PubMed     Text format     Abstract available

    Gastroenterology. 2015;149:508-9.
    PubMed     Text format    

  63. LOOMBA R, Chalasani N
    The Hierarchical Model of NAFLD: Prognostic Significance of Histologic Features in NASH.
    Gastroenterology. 2015;149:278-81.
    PubMed     Text format    

  64. ANGULO P, Kleiner DE, Dam-Larsen S, Adams LA, et al
    Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease.
    Gastroenterology. 2015;149:389-97.
    PubMed     Text format     Abstract available

    July 2015
  65. MEHTA A, Singal AG
    Hepatocellular Carcinoma Surveillance: Does Alpha-Fetoprotein Have a Role?
    Gastroenterology. 2015 Jul 28. pii: S0016-5085(15)01012.
    PubMed     Text format    

  66. KOFF RS
    Cirrhosis: A Practical Guide to Management.
    Gastroenterology. 2015 Jul 25. pii: S0016-5085(15)01011.
    PubMed     Text format    

  67. LAWITZ E, Makara M, Akarca US, Thuluvath PJ, et al
    Efficacy and Safety of Ombitasvir, Paritaprevir, and Ritonavir in an Open-label Study of Patients With Genotype 1b Chronic Hepatitis C Virus, With and Without Cirrhosis.
    Gastroenterology. 2015 Jul 10. pii: S0016-5085(15)00936.
    PubMed     Text format     Abstract available

    June 2015
  68. DONG R, Zheng S, Chen G
    The Appropriate Timing and Dose of Obeticholic Acid in Patients With Primary Biliary Cirrhosis.
    Gastroenterology. 2015 Jun 29. pii: S0016-5085(15)00864.
    PubMed     Text format    

    May 2015
  69. SAUERBRUCH T, Mengel M, Dollinger M, Zipprich A, et al
    Prevention of Rebleeding from Esophageal Varices in Patients with Cirrhosis Receiving Small-diameter Stents vs Hemodynamically Controlled Medical Therapy.
    Gastroenterology. 2015 May 16. pii: S0016-5085(15)00683.
    PubMed     Text format     Abstract available

  70. CHARLTON M, Everson GT, Flamm SL, Kumar P, et al
    Ledipasvir and Sofosbuvir Plus Ribavirin for Treatment of HCV Infection in Patients with Advanced Liver Disease.
    Gastroenterology. 2015 May 15. pii: S0016-5085(15)00682.
    PubMed     Text format     Abstract available

    April 2015
  71. BETTAIEB A, Jiang JX, Sasaki Y, Chao TI, et al
    Hepatocyte NADPH Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice.
    Gastroenterology. 2015 Apr 14. pii: S0016-5085(15)00509.
    PubMed     Text format     Abstract available

  72. LAMMERS WJ, van Buuren HR, Hirschfield GM, Hansen BE, et al
    Reply: To PMID 25160979.
    Gastroenterology. 2015;148:860-1.
    PubMed     Text format    

    Targeting the FXR nuclear receptor to treat liver disease.
    Gastroenterology. 2015;148:704-6.
    PubMed     Text format    

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