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  Neoplasms of the CNS

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Articles published in Acta Neuropathol

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Single Articles


    November 2017
  1. BOGEAS A, Morvan-Dubois G, El-Habr EA, Lejeune FX, et al
    Changes in chromatin state reveal ARNT2 at a node of a tumorigenic transcription factor signature driving glioblastoma cell aggressiveness.
    Acta Neuropathol. 2017 Nov 17. doi: 10.1007/s00401-017-1783.
    PubMed     Text format     Abstract available


    October 2017
  2. LOPEZ GY, Oberheim Bush NA, Phillips JJ, Bouffard JP, et al
    Diffuse midline gliomas with subclonal H3F3A K27M mutation and mosaic H3.3 K27M mutant protein expression.
    Acta Neuropathol. 2017 Oct 23. doi: 10.1007/s00401-017-1780.
    PubMed     Text format    


  3. WIJNENGA MMJ, Dubbink HJ, French PJ, Synhaeve NE, et al
    Molecular and clinical heterogeneity of adult diffuse low-grade IDH wild-type gliomas: assessment of TERT promoter mutation and chromosome 7 and 10 copy number status allows superior prognostic stratification.
    Acta Neuropathol. 2017 Oct 19. doi: 10.1007/s00401-017-1781.
    PubMed     Text format    


  4. BEYER U, Brand F, Martens H, Weder J, et al
    Rare ADAR and RNASEH2B variants and a type I interferon signature in glioma and prostate carcinoma risk and tumorigenesis.
    Acta Neuropathol. 2017 Oct 13. doi: 10.1007/s00401-017-1774.
    PubMed     Text format     Abstract available


  5. KORSHUNOV A, Chavez L, Northcott PA, Sharma T, et al
    DNA-methylation profiling discloses significant advantages over NanoString method for molecular classification of medulloblastoma.
    Acta Neuropathol. 2017 Oct 13. doi: 10.1007/s00401-017-1776.
    PubMed     Text format    


    August 2017
  6. NOMURA M, Mukasa A, Nagae G, Yamamoto S, et al
    Distinct molecular profile of diffuse cerebellar gliomas.
    Acta Neuropathol. 2017 Aug 29. doi: 10.1007/s00401-017-1771.
    PubMed     Text format     Abstract available


  7. D'ARONCO L, Rouleau C, Gayden T, Crevier L, et al
    Brainstem angiocentric gliomas with MYB-QKI rearrangements.
    Acta Neuropathol. 2017 Aug 12. doi: 10.1007/s00401-017-1763.
    PubMed     Text format    


  8. LOUIS DN, von Deimling A
    Grading of diffuse astrocytic gliomas: Broders, Kernohan, Zulch, the WHO... and Shakespeare.
    Acta Neuropathol. 2017 Aug 11. doi: 10.1007/s00401-017-1765.
    PubMed     Text format    


  9. CHAN E, Bollen AW, Sirohi D, Van Ziffle J, et al
    Angiocentric glioma with MYB-QKI fusion located in the brainstem, rather than cerebral cortex.
    Acta Neuropathol. 2017 Aug 3. doi: 10.1007/s00401-017-1759.
    PubMed     Text format    


  10. SINGH M, Venugopal C, Tokar T, Brown KR, et al
    RNAi screen identifies essential regulators of human brain metastasis-initiating cells.
    Acta Neuropathol. 2017 Aug 1. doi: 10.1007/s00401-017-1757.
    PubMed     Text format     Abstract available


    July 2017
  11. NEUMANN JE, Swartling FJ, Schuller U
    Medulloblastoma: experimental models and reality.
    Acta Neuropathol. 2017 Jul 19. doi: 10.1007/s00401-017-1753.
    PubMed     Text format     Abstract available


    June 2017
  12. EUSKIRCHEN P, Bielle F, Labreche K, Kloosterman WP, et al
    Same-day genomic and epigenomic diagnosis of brain tumors using real-time nanopore sequencing.
    Acta Neuropathol. 2017 Jun 21. doi: 10.1007/s00401-017-1743.
    PubMed     Text format     Abstract available


    May 2017
  13. SAHM F, Toprak UH, Hubschmann D, Kleinheinz K, et al
    Meningiomas induced by low-dose radiation carry structural variants of NF2 and a distinct mutational signature.
    Acta Neuropathol. 2017 May 4. doi: 10.1007/s00401-017-1715.
    PubMed     Text format    


    April 2017
  14. KORSHUNOV A, Schrimpf D, Ryzhova M, Sturm D, et al
    H3-/IDH-wild type pediatric glioblastoma is comprised of molecularly and prognostically distinct subtypes with associated oncogenic drivers.
    Acta Neuropathol. 2017 Apr 11. doi: 10.1007/s00401-017-1710.
    PubMed     Text format     Abstract available


  15. PUSCH S, Krausert S, Fischer V, Balss J, et al
    Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo.
    Acta Neuropathol. 2017;133:629-644.
    PubMed     Text format     Abstract available


    March 2017
  16. RAPP C, Warta R, Stamova S, Nowrouzi A, et al
    Identification of T cell target antigens in glioblastoma stem-like cells using an integrated proteomics-based approach in patient specimens.
    Acta Neuropathol. 2017 Mar 22. doi: 10.1007/s00401-017-1702.
    PubMed     Text format     Abstract available


  17. PEKMEZCI M, Rice T, Molinaro AM, Walsh KM, et al
    Adult infiltrating gliomas with WHO 2016 integrated diagnosis: additional prognostic roles of ATRX and TERT.
    Acta Neuropathol. 2017 Mar 2. doi: 10.1007/s00401-017-1690.
    PubMed     Text format     Abstract available


  18. FUKUSHIMA S, Yamashita S, Kobayashi H, Takami H, et al
    Genome-wide methylation profiles in primary intracranial germ cell tumors indicate a primordial germ cell origin for germinomas.
    Acta Neuropathol. 2017;133:445-462.
    PubMed     Text format     Abstract available


  19. HUSE JT, Snuderl M, Jones DT, Brathwaite CD, et al
    Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway.
    Acta Neuropathol. 2017;133:417-429.
    PubMed     Text format     Abstract available


    January 2017
  20. OLAR A, Wani KM, Wilson CD, Zadeh G, et al
    Global epigenetic profiling identifies methylation subgroups associated with recurrence-free survival in meningioma.
    Acta Neuropathol. 2017 Jan 27. doi: 10.1007/s00401-017-1678.
    PubMed     Text format     Abstract available


  21. LENTING K, Verhaak R, Ter Laan M, Wesseling P, et al
    Glioma: experimental models and reality.
    Acta Neuropathol. 2017 Jan 10. doi: 10.1007/s00401-017-1671.
    PubMed     Text format     Abstract available


  22. PAJTLER KW, Mack SC, Ramaswamy V, Smith CA, et al
    The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants.
    Acta Neuropathol. 2017;133:5-12.
    PubMed     Text format     Abstract available


    December 2016
  23. EL-HABR EA, Dubois LG, Burel-Vandenbos F, Bogeas A, et al
    A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma.
    Acta Neuropathol. 2016 Dec 28. doi: 10.1007/s00401-016-1659.
    PubMed     Text format     Abstract available


    August 2016
  24. TABOURET E, Nguyen AT, Dehais C, Carpentier C, et al
    Prognostic impact of the 2016 WHO classification of diffuse gliomas in the French POLA cohort.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


    July 2016
  25. BAUMGARTEN P, Gessler F, Schittenhelm J, Skardelly M, et al
    Brain invasion in otherwise benign meningiomas does not predict tumor recurrence.
    Acta Neuropathol. 2016.
    PubMed     Text format    


    May 2016
  26. FERRIS SP, Goode B, Joseph NM, Kline CN, et al
    IDH1 mutation can be present in diffuse astrocytomas and giant cell glioblastomas of young children under 10 years of age.
    Acta Neuropathol. 2016.
    PubMed     Text format    


  27. CASTEL D, Grill J, Debily MA
    Histone H3 genotyping refines clinico-radiological diagnostic and prognostic criteria in DIPG.
    Acta Neuropathol. 2016;131:795-6.
    PubMed     Text format    


    April 2016
  28. RAMASWAMY V, Remke M, Bouffet E, Bailey S, et al
    Risk stratification of childhood medulloblastoma in the molecular era: the current consensus.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


    March 2016
  29. JANSEN MH, Veldhuijzen van Zanten SE, Heymans MW, Hargrave D, et al
    Commentary on "Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes".
    Acta Neuropathol. 2016.
    PubMed     Text format    


    January 2016
  30. BRONISCER A, Chamdine O, Hwang S, Lin T, et al
    Gliomatosis cerebri in children shares molecular characteristics with other pediatric gliomas.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


  31. HERRLINGER U, Jones DT, Glas M, Hattingen E, et al
    Erratum to: Gliomatosis cerebri: no evidence for a separate brain tumor entity.
    Acta Neuropathol. 2016.
    PubMed     Text format    


    December 2015
  32. BRANDENBURG S, Muller A, Turkowski K, Radev YT, et al
    Resident microglia rather than peripheral macrophages promote vascularization in brain tumors and are source of alternative pro-angiogenic factors.
    Acta Neuropathol. 2015.
    PubMed     Text format     Abstract available


  33. SAHM F, Schrimpf D, Jones DT, Meyer J, et al
    Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets.
    Acta Neuropathol. 2015.
    PubMed     Text format     Abstract available


    October 2015
  34. HERRLINGER U, Jones DT, Glas M, Hattingen E, et al
    Gliomatosis cerebri: no evidence for a separate brain tumor entity.
    Acta Neuropathol. 2015.
    PubMed     Text format     Abstract available


    September 2015
  35. CASTEL D, Philippe C, Calmon R, Le Dret L, et al
    Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes.
    Acta Neuropathol. 2015.
    PubMed     Text format     Abstract available


  36. LIU Q, Liu Y, Li W, Wang X, et al
    Genetic, epigenetic, and molecular landscapes of multifocal and multicentric glioblastoma.
    Acta Neuropathol. 2015.
    PubMed     Text format     Abstract available


    August 2015
  37. HO CY, Mobley BC, Gordish-Dressman H, VandenBussche CJ, et al
    A clinicopathologic study of diencephalic pediatric low-grade gliomas with BRAF V600 mutation.
    Acta Neuropathol. 2015.
    PubMed     Text format     Abstract available


  38. GESSI M, Gielen GH, Dreschmann V, Waha A, et al
    High frequency of H3F3A mutations characterizes pediatric and adult high-grade gliomas of the spinal cord.
    Acta Neuropathol. 2015.
    PubMed     Text format    


    July 2015
  39. MENKE JR, Raleigh DR, Gown AM, Thomas S, et al
    Somatostatin receptor 2a is a more sensitive diagnostic marker of meningioma than epithelial membrane antigen.
    Acta Neuropathol. 2015.
    PubMed     Text format    


    June 2015
  40. LIVERMAN C, Mafra M, Chuang SS, Shivane A, et al
    A clinicopathologic study of 11 rosette-forming meningiomas: a rare and potentially confusing pattern.
    Acta Neuropathol. 2015.
    PubMed     Text format    


  41. OHLI J, Neumann JE, Grammel D, Schuller U, et al
    Localization of SHH medulloblastoma in mice depends on the age at its initiation.
    Acta Neuropathol. 2015.
    PubMed     Text format    


  42. ICHIMURA K, Narita Y, Hawkins CE
    Diffusely infiltrating astrocytomas: pathology, molecular mechanisms and markers.
    Acta Neuropathol. 2015;129:789-808.
    PubMed     Text format     Abstract available


  43. REUSS DE, Mamatjan Y, Schrimpf D, Capper D, et al
    IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO.
    Acta Neuropathol. 2015;129:867-73.
    PubMed     Text format     Abstract available


  44. WESSELING P, van den Bent M, Perry A
    Oligodendroglioma: pathology, molecular mechanisms and markers.
    Acta Neuropathol. 2015;129:809-27.
    PubMed     Text format     Abstract available


  45. THOMAS C, Ruland V, Kordes U, Hartung S, et al
    Pediatric atypical choroid plexus papilloma reconsidered: increased mitotic activity is prognostic only in older children.
    Acta Neuropathol. 2015;129:925-7.
    PubMed     Text format    


  46. DE LA FOUCHARDIERE A, Cabaret O, Petre J, Aydin S, et al
    Primary leptomeningeal melanoma is part of the BAP1-related cancer syndrome.
    Acta Neuropathol. 2015;129:921-3.
    PubMed     Text format    


  47. COLLINS VP, Jones DT, Giannini C
    Pilocytic astrocytoma: pathology, molecular mechanisms and markers.
    Acta Neuropathol. 2015;129:775-88.
    PubMed     Text format     Abstract available


    May 2015
  48. PAULUS W
    Pathology, molecular mechanisms and markers of gliomas: new insight and new challenges.
    Acta Neuropathol. 2015.
    PubMed     Text format    


    April 2015
  49. RODRIGUEZ FJ, Schniederjan MJ, Nicolaides T, Tihan T, et al
    High rate of concurrent BRAF-KIAA1549 gene fusion and 1p deletion in disseminated oligodendroglioma-like leptomeningeal neoplasms (DOLN).
    Acta Neuropathol. 2015;129:609-10.
    PubMed     Text format    


    January 2015
  50. SAHM F, von Deimling A
    Farewell to oligoastrocytoma: response to letters.
    Acta Neuropathol. 2015;129:155.
    PubMed     Text format    


  51. WILCOX P, Li CC, Lee M, Shivalingam B, et al
    Oligoastrocytomas: throwing the baby out with the bathwater?
    Acta Neuropathol. 2015;129:147-9.
    PubMed     Text format    


    October 2014
  52. SAHM F, Reuss D, Koelsche C, Capper D, et al
    Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma.
    Acta Neuropathol. 2014;128:551-9.
    PubMed     Text format     Abstract available


  53. DE KOCK L, Sabbaghian N, Druker H, Weber E, et al
    Germ-line and somatic DICER1 mutations in pineoblastoma.
    Acta Neuropathol. 2014;128:583-95.
    PubMed     Text format     Abstract available


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