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  Neoplasms of the CNS

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Articles published in Cancer Res

Retrieve available abstracts of 69 articles:
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    August 2017
  1. CHOW KH, Park HJ, George J, Yamamoto K, et al
    S100A4 is a biomarker and regulator of glioma stem cells that is critical for mesenchymal transition in glioblastoma.
    Cancer Res. 2017 Aug 14. pii: canres.1294.2017.
    PubMed     Text format     Abstract available


  2. CHEN X, Ma H, Wang Z, Zhang S, et al
    EZH2 palmitoylation mediated by ZDHHC5 in p53 mutant glioma drives malignant development and progression.
    Cancer Res. 2017 Aug 3. pii: canres.1139.2017.
    PubMed     Text format     Abstract available


    July 2017
  3. YIN J, Oh YT, Kim JY, Kim SS, et al
    Transglutaminase 2 inhibition reverses mesenchymal transdifferentiation of glioma stem cells by regulating C/EBPbeta signaling.
    Cancer Res. 2017 Jul 28. pii: canres.0388.2017.
    PubMed     Text format     Abstract available


  4. WANG X, Huang Z, Wu Q, Prager BC, et al
    MYC-regulated Mevalonate Metabolism Maintains Brain Tumor Initiating Cells.
    Cancer Res. 2017 Jul 20. pii: canres.0114.2017.
    PubMed     Text format     Abstract available



  5. Correction: Wnt5a Drives an Invasive Phenotype in Human Glioblastoma Stem-like Cells.
    Cancer Res. 2017;77:3962.
    PubMed     Text format    


    May 2017
  6. YAN H, Romero-Lopez M, Benitez LI, Di K, et al
    3D mathematical modeling of glioblastoma suggests that transdifferentiated vascular endothelial cells mediate resistance to current standard-of-care therapy.
    Cancer Res. 2017 May 23. pii: canres.3094.2016.
    PubMed     Text format     Abstract available


  7. TECH K, Tikunov AP, Farooq H, Morrissy AS, et al
    Pyruvate kinase inhibits proliferation during postnatal cerebellar neurogenesis and suppresses medulloblastoma formation.
    Cancer Res. 2017 May 17. pii: canres.3304.2016.
    PubMed     Text format     Abstract available


  8. ZHANG Y, Cruickshanks N, Yuan F, Wang B, et al
    Targetable T-type calcium channels drive glioblastoma.
    Cancer Res. 2017 May 16. pii: canres.2347.2016.
    PubMed     Text format     Abstract available


  9. GRAUSAM KB, Dooyema SD, Bihannic L, Premathilake H, et al
    ATOH1 promotes leptomeningeal dissemination and metastasis of Sonic Hedgehog subgroup medulloblastomas.
    Cancer Res. 2017 May 10. pii: canres.1836.2016.
    PubMed     Text format     Abstract available


    April 2017
  10. SARKAR S, Mirzaei R, Zemp FJ, Wu W, et al
    Activation of NOTCH signaling by tenascin-C promotes growth of human brain tumor-initiating cells.
    Cancer Res. 2017 Apr 17. pii: canres.2171.2016.
    PubMed     Text format     Abstract available


  11. STEVENS LE, Cheung WKC, Adua SJ, Arnal-Estape A, et al
    Extracellular Matrix Receptor Expression in Subtypes of Lung Adenocarcinoma Potentiates Outgrowth of Micrometastases.
    Cancer Res. 2017;77:1905-1917.
    PubMed     Text format     Abstract available


  12. ZINNHARDT B, Pigeon H, Theze B, Viel T, et al
    Combined PET Imaging of the Inflammatory Tumor Microenvironment Identifies Margins of Unique Radiotracer Uptake.
    Cancer Res. 2017;77:1831-1841.
    PubMed     Text format     Abstract available


  13. SCHNEPP PM, Lee DD, Guldner IH, O'Tighearnaigh TK, et al
    GAD1 Upregulation Programs Aggressive Features of Cancer Cell Metabolism in the Brain Metastatic Microenvironment.
    Cancer Res. 2017 Apr 11. pii: canres.2289.2016.
    PubMed     Text format     Abstract available


    February 2017
  14. CHEN Z, Feng X, Herting CJ, Alvarez Garcia V, et al
    Cellular and molecular identity of tumor-associated macrophages in glioblastoma.
    Cancer Res. 2017 Feb 24. pii: canres.2310.2016.
    PubMed     Text format     Abstract available


  15. LU Y, Kwintkiewicz J, Liu Y, Tech K, et al
    Chemosensitivity of IDH1 mutant gliomas due to an impairment in PARP1-mediated DNA repair.
    Cancer Res. 2017 Feb 15. pii: canres.2773.2016.
    PubMed     Text format     Abstract available


    January 2017
  16. KOSSATZ S, Carney B, Schweitzer ME, Carlucci G, et al
    Biomarker based PET Imaging of Diffuse Intrinsic Pontine Glioma in Mouse Models.
    Cancer Res. 2017 Jan 20. pii: canres.2850.2016.
    PubMed     Text format     Abstract available


  17. NIKLASSON M, Maddalo G, Sramkova Z, Mutlu E, et al
    Membrane-depolarizing channel blockers induce selective glioma cell death by impairing nutrient transport and unfolded protein/amino acid responses.
    Cancer Res. 2017 Jan 13. pii: canres.2274.2016.
    PubMed     Text format     Abstract available


    December 2016
  18. WARD SA, Warrington NM, Taylor S, Kfoury N, et al
    Reprogramming medulloblastoma-propagating cells via combined antagonism of Sonic Hedgehog and CXCR4.
    Cancer Res. 2016 Dec 28. pii: canres.0847.2016.
    PubMed     Text format     Abstract available


  19. BINDA E, Visioli A, Giani F, Trivieri N, et al
    Wnt5a drives an invasive phenotype in human glioblastoma stem-like cells.
    Cancer Res. 2016 Dec 23. pii: canres.1693.2016.
    PubMed     Text format     Abstract available



  20. Correction: IFN-beta Down-Regulates the Expression of DNA Repair Gene MGMT and Sensitizes Resistant Glioma Cells to Temozolomide.
    Cancer Res. 2016;76:7293.
    PubMed     Text format    


  21. WAHL DR, Dresser J, Wilder-Romans K, Parsels JD, et al
    Glioblastoma therapy can be augmented by targeting IDH1-mediated NADPH biosynthesis.
    Cancer Res. 2016 Dec 6. pii: canres.2008.2016.
    PubMed     Text format     Abstract available


    November 2016
  22. SREEDHARAN S, Maturi NP, Xie Y, Sundstrom A, et al
    Mouse Models of Pediatric Supratentorial High-grade Glioma Reveal How Cell-of-Origin Influences Tumor Development and Phenotype.
    Cancer Res. 2016 Nov 15. doi: 10.1158/0008-5472.CAN-16-2482.
    PubMed     Text format     Abstract available


  23. MITTAPALLI RK, Adkins CE, Bohn KA, Mohammad AS, et al
    Quantitative Fluorescent Microscopy to Measure Vascular Pore Sizes in Primary and Metastatic Brain Tumors.
    Cancer Res. 2016 Nov 4. pii: canres.1711.2016.
    PubMed     Text format     Abstract available


  24. ZHU G, Rankin SL, Larson JD, Zhu X, et al
    PTEN signaling in the postnatal perivascular progenitor niche drives medulloblastoma formation.
    Cancer Res. 2016 Nov 4. pii: canres.1991.2016.
    PubMed     Text format     Abstract available


    October 2016
  25. NAGEL ZD, Kitange GJ, Gupta SK, Joughin BA, et al
    DNA repair capacity in multiple pathways predicts chemoresistance in glioblastoma multiforme.
    Cancer Res. 2016 Oct 28. pii: canres.1151.2016.
    PubMed     Text format     Abstract available


    September 2016
  26. KAUR A, Denisova O, Qiao X, Jumppanen M, et al
    PP2A inhibitor PME-1 drives kinase inhibitor resistance in glioma cells.
    Cancer Res. 2016 Sep 26. pii: canres.1134.2016.
    PubMed     Text format     Abstract available


    August 2016
  27. CHENG P, Wang J, Waghmare I, Sartini S, et al
    FOXD1-ALDH1A3 signaling is a determinant for the self-renewal and tumorigenicity of mesenchymal glioma stem cells.
    Cancer Res. 2016 Aug 28. pii: canres.2860.2015.
    PubMed     Text format     Abstract available


  28. CHANG AL, Miska J, Wainwright DA, Dey M, et al
    CCL2 produced by the glioma microenvironment is essential for the recruitment of regulatory T cells and myeloid-derived suppressor cells.
    Cancer Res. 2016 Aug 16. pii: canres.0144.2016.
    PubMed     Text format     Abstract available


  29. FILATOVA A, Seidel S, Bogurcu N, Graf S, et al
    Acidosis acts through HSP90 in a PHD/VHL-independent manner to promote HIF function and stem cell maintenance in glioma.
    Cancer Res. 2016 Aug 3. pii: canres.2630.2015.
    PubMed     Text format     Abstract available


    July 2016
  30. FERREYRA SOLARI N, Belforte FS, Canedo L, Videla Richardson GA, et al
    The NSL chromatin-modifying complex subunit KANSL2 regulates cancer stem-like properties in glioblastoma that contribute to tumorigenesis.
    Cancer Res. 2016 Jul 12. pii: canres.3159.2015.
    PubMed     Text format     Abstract available


  31. DOMINGUEZ VALENTIN M, Gras Navarro A, Rahman AM, Kumar S, et al
    Identification of a natural killer cell receptor allele that prolongs survival of cytomegalovirus-positive glioblastoma patients.
    Cancer Res. 2016 Jul 12. pii: canres.1162.2016.
    PubMed     Text format     Abstract available


    June 2016
  32. XING F, Liu Y, Sharma S, Wu K, et al
    Activation of the c-Met pathway mobilizes an inflammatory network in the brain microenvironment to promote brain metastasis of breast cancer.
    Cancer Res. 2016 Jun 30. pii: canres.3541.2015.
    PubMed     Text format     Abstract available


  33. AGNIHOTRI S, Golbourn B, Huang X, Remke M, et al
    PINK1 is a Negative Regulator of Growth and the Warburg Effect in Glioblastoma.
    Cancer Res. 2016 Jun 20. pii: canres.3079.2015.
    PubMed     Text format     Abstract available


  34. SCHWARTZ H, Blacher E, Amer M, Livneh N, et al
    Incipient melanoma brain metastases instigate astrogliosis and neuroinflammation.
    Cancer Res. 2016 Jun 3. pii: canres.0485.2016.
    PubMed     Text format     Abstract available


    May 2016
  35. XUE J, Zhou A, Wu Y, Morris SA, et al
    STAT3 activation promotes glioma tumorigenesis by inducing miR-182-5p.
    Cancer Res. 2016 May 31. pii: canres.3073.2015.
    PubMed     Text format     Abstract available


    April 2016
  36. CROWTHER A, Ocasio J, Fang F, Meidinger J, et al
    Radiation sensitivity in a preclinical mouse model of medulloblastoma relies on the function of the intrinsic apoptotic pathway.
    Cancer Res. 2016 Apr 13. pii: canres.0025.2015.
    PubMed     Text format     Abstract available


    March 2016
  37. CHAN T, Hawkins C, Krieger JR, McGlade CJ, et al
    JPO2/CDCA7L and LEDGF/p75 are novel mediators of PI3K/AKT signalling and aggressive phenotypes in medulloblastoma.
    Cancer Res. 2016 Mar 24. pii: canres.2194.2015.
    PubMed     Text format     Abstract available


  38. DE I, Steffen MD, Clark PA, Patros CJ, et al
    CSF1 overexpression promotes high-grade glioma formation without impacting the polarization status of glioma-associated microglia and macrophages.
    Cancer Res. 2016 Mar 24. pii: canres.2386.2015.
    PubMed     Text format     Abstract available


  39. RICKLEFS F, Mineo M, Rooj AK, Nakano I, et al
    Extracellular vesicles from high grade glioma exchange diverse pro-oncogenic signals that maintain intratumoral heterogeneity.
    Cancer Res. 2016 Mar 24. pii: canres.3432.2015.
    PubMed     Text format     Abstract available


  40. WAHBA A, Rath BH, Bisht K, Camphausen K, et al
    Polysome profiling links translational control to the radioresponse of glioblastoma stem-like cells.
    Cancer Res. 2016 Mar 22. pii: canres.3050.2015.
    PubMed     Text format     Abstract available


  41. TSUCHIHASHI K, Okazaki S, Ohmura M, Ishikawa M, et al
    The EGF receptor promotes the malignant potential of glioma by regulating amino acid transport system xc(-).
    Cancer Res. 2016 Mar 15. pii: canres.2121.2015.
    PubMed     Text format     Abstract available


  42. FUKAYA R, Ohta S, Yaguchi T, Matsuzaki Y, et al
    MIF maintains the tumorigenic capacity of brain tumor-initiating cells by directly inhibiting p53.
    Cancer Res. 2016 Mar 15. pii: canres.1011.2015.
    PubMed     Text format     Abstract available


  43. WANG H, Peng C, Chen Z, Wang S, et al
    The error-prone DNA polymerase kappa promotes temozolomide resistance in glioblastoma through Rad17-dependent activation of ATR-Chk1 signaling.
    Cancer Res. 2016 Mar 9. pii: canres.1884.2015.
    PubMed     Text format     Abstract available


  44. RAHME GJ, Zhang Z, Young AL, Cheng C, et al
    PDGF Engages an E2F-USP1 Signaling Pathway to Support ID2-mediated Survival of Proneural Glioma Cells.
    Cancer Res. 2016 Mar 7. pii: canres.2157.2015.
    PubMed     Text format     Abstract available


  45. KOSO H, Yi H, Sheridan P, Miyano S, et al
    Identification of RNA-binding protein LARP4B as a tumor suppressor in glioma.
    Cancer Res. 2016 Mar 1. pii: canres.2308.2015.
    PubMed     Text format     Abstract available


    February 2016
  46. DERMAWAN JK, Hitomi M, Silver DJ, Wu Q, et al
    Pharmacological targeting of the histone chaperone complex FACT preferentially eliminates glioblastoma stem cells and prolongs survival in preclinical models.
    Cancer Res. 2016 Feb 26. pii: canres.2162.2015.
    PubMed     Text format     Abstract available


  47. GOUAZE-ANDERSSON V, Delmas C, Taurand M, Martinez-Gala J, et al
    FGFR1 induces glioblastoma radioresistance through the PLCgamma/HIF1alpha pathway.
    Cancer Res. 2016 Feb 19. pii: canres.2058.2015.
    PubMed     Text format     Abstract available


  48. HUBERT CG, Rivera M, Spangler LC, Wu Q, et al
    A three-dimensional organoid culture system derived from human glioblastomas recapitulates the hypoxic gradients and cancer stem cell heterogeneity of tumors found in vivo.
    Cancer Res. 2016 Feb 19. pii: canres.2402.2015.
    PubMed     Text format     Abstract available


  49. MUKHERJEE S, Tucker-Burden C, Zhang C, Moberg K, et al
    Drosophila Brat and human ortholog TRIM3 maintain stem cell equilibrium and suppress brain tumorigenesis by attenuating Notch nuclear transport.
    Cancer Res. 2016 Feb 18. pii: canres.2299.2015.
    PubMed     Text format     Abstract available


    January 2016
  50. ERDEM-ERASLAN L, van den Bent MJ, Hoogstrate Y, Naz-Khan H, et al
    Identification of Patients with Recurrent Glioblastoma Who May Benefit from Combined Bevacizumab and CCNU Therapy: A Report from the BELOB Trial.
    Cancer Res. 2016.
    PubMed     Text format     Abstract available


    December 2015
  51. OHTSU N, Nakatani Y, Yamashita D, Ohue S, et al
    Eva1 Maintains the Stem-like Character of Glioblastoma-Initiating Cells by Activating the Noncanonical NF-kappaB Signaling Pathway.
    Cancer Res. 2015.
    PubMed     Text format     Abstract available


  52. EMIR UE, Larkin SJ, de Pennington N, Voets N, et al
    Noninvasive Quantification of 2-Hydroxyglutarate in Human Gliomas with IDH1 and IDH2 Mutations.
    Cancer Res. 2015.
    PubMed     Text format     Abstract available


  53. HAN J, Chen X, Chu J, Xu B, et al
    TGFbeta Treatment Enhances Glioblastoma Virotherapy by Inhibiting the Innate Immune Response.
    Cancer Res. 2015.
    PubMed     Text format     Abstract available


    November 2015
  54. LERNER RG, Grossauer S, Kadkhodaei B, Meyers I, et al
    Targeting a Plk1-controlled polarity checkpoint in therapy-resistant glioblastoma-propagating cells.
    Cancer Res. 2015 Nov 16. pii: canres.3689.2014.
    PubMed     Text format     Abstract available


  55. MURPHY SF, Varghese RT, Lamouille S, Guo S, et al
    Connexin 43 inhibition sensitizes chemoresistant glioblastoma cells to temozolomide.
    Cancer Res. 2015 Nov 5. pii: canres.1286.2015.
    PubMed     Text format     Abstract available


  56. NG JM, Martinez D, Marsh ED, Zhang Z, et al
    Generation of a mouse model of atypical teratoid/rhabdoid tumor of the central nervous system through combined deletion of Snf5 and p53.
    Cancer Res. 2015;75:4629-39.
    PubMed     Text format     Abstract available


    September 2015
  57. LANGENKAMP E, Zhang L, Lugano R, Huang H, et al
    Elevated expression of the C-type lectin CD93 in the glioblastoma vasculature regulates cytoskeletal rearrangements that enhance vessel function and reduce host survival.
    Cancer Res. 2015 Sep 11. pii: canres.3636.2014.
    PubMed     Text format     Abstract available


    August 2015
  58. FRANOVIC A, Elliott KC, Seguin L, Camargo MF, et al
    Glioblastomas require integrin alphavbeta3/PAK4 signaling to escape senescence.
    Cancer Res. 2015 Aug 21. pii: canres.0988.2015.
    PubMed     Text format     Abstract available


  59. AHMED SU, Carruthers R, Gilmour L, Yildirim S, et al
    Selective inhibition of parallel DNA damage response pathways optimizes radiosensitization of glioblastoma stem-like cells.
    Cancer Res. 2015 Aug 17. pii: canres.3790.2014.
    PubMed     Text format     Abstract available


  60. LAU J, Ilkhanizadeh S, Wang S, Miroshnikova YA, et al
    STAT3 blockade inhibits radiation-induced malignant progression in glioma.
    Cancer Res. 2015 Aug 17. pii: canres.3331.2014.
    PubMed     Text format     Abstract available


  61. KANEKO S, Nakatani Y, Takezaki T, Hide T, et al
    Ceacam1L modulates STAT3 signaling to control the proliferation of glioblastoma-initiating cells.
    Cancer Res. 2015 Aug 3. pii: canres.0412.2015.
    PubMed     Text format     Abstract available


  62. SOROCEANU L, Matlaf L, Khan S, Akhavan A, et al
    Cytomegalovirus Immediate-Early Proteins Promote Stemness Properties in Glioblastoma.
    Cancer Res. 2015;75:3065-76.
    PubMed     Text format     Abstract available


    July 2015
  63. MORFOUACE M, Cheepala SB, Jackson S, Fukuda Y, et al
    ABCG2 transporter expression impacts Group3 Medulloblastoma response to chemotherapy.
    Cancer Res. 2015 Jul 21. pii: canres.0030.2015.
    PubMed     Text format     Abstract available


    June 2015
  64. MOUTAL A, Honnorat J, Massoma P, Desormeaux P, et al
    CRMP5 controls glioblastoma cell proliferation and survival through Notch-dependent signaling.
    Cancer Res. 2015 Jun 29. pii: canres.0631.2014.
    PubMed     Text format     Abstract available


  65. YUE P, Lopez-Tapia F, Paladino D, Li Y, et al
    Hydroxamic acid and benzoic acid-based Stat3 inhibitors suppress human glioma and breast cancer phenotypes in vitro and in vivo.
    Cancer Res. 2015 Jun 18. pii: canres.3558.2014.
    PubMed     Text format     Abstract available


    May 2015
  66. MCFALINE-FIGUEROA JL, Braun CJ, Stanciu M, Nagel ZD, et al
    Minor changes in expression of the mismatch repair protein MSH2 exert a major impact on glioblastoma response to temozolomide.
    Cancer Res. 2015 May 29. pii: canres.3616.2014.
    PubMed     Text format     Abstract available


    April 2015
  67. JAMIN Y, Boult JK, Li J, Popov S, et al
    Exploring the biomechanical properties of brain malignancies and their pathologic determinants in vivo with magnetic resonance elastography.
    Cancer Res. 2015;75:1216-24.
    PubMed     Text format     Abstract available


  68. RICE WL, Shcherbakova DM, Verkhusha VV, Kumar AT, et al
    In vivo tomographic imaging of deep-seated cancer using fluorescence lifetime contrast.
    Cancer Res. 2015;75:1236-43.
    PubMed     Text format     Abstract available


    December 2014
  69. CHEN J, Lee HJ, Wu X, Huo L, et al
    Gain of glucose-independent growth upon metastasis of breast cancer cells to the brain.
    Cancer Res. 2014 Dec 15. pii: canres.2268.2014.
    PubMed     Text format     Abstract available


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