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	The Medical Article of the Year 2008: Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78. Free full-text

Neoplasms of the CNS

Free Subscription Articles published in Cancer Res Retrieve available abstracts of 146 articles: HTML format

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July 2008
1. LIANG XJ , Choi Y, Sackett DL, Park JK, et al
   Nitrosoureas inhibit the stathmin-mediated migration and invasion of malignant glioma cells.
   Cancer Res. 2008;68:5267-72.
   PubMed     Related articles    Abstract available
   
   
   June 2008
2. JURVANSUU J , Zhao Y, Leung DS, Boulaire J, et al
   Transmembrane protein 18 enhances the tropism of neural stem cells for glioma cells.
   Cancer Res. 2008;68:4614-22.
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   May 2008
3. KEFAS B , Godlewski J, Comeau L, Li Y, et al
   microRNA-7 Inhibits the Epidermal Growth Factor Receptor and the Akt Pathway and Is Down-regulated in Glioblastoma.
   Cancer Res. 2008;68:3566-72.
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4. LU X , Yang C, Hill R, Yin C, et al
   Inactivation of gadd45a sensitizes epithelial cancer cells to ionizing radiation in vivo resulting in prolonged survival.
   Cancer Res. 2008;68:3579-83.
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5. GEIGER GA , Fu W, Kao GD
   Temozolomide-mediated radiosensitization of human glioma cells in a zebrafish embryonic system.
   Cancer Res. 2008;68:3396-404.
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6. KWON CH , Zhao D, Chen J, Alcantara S, et al
   Pten haploinsufficiency accelerates formation of high-grade astrocytomas.
   Cancer Res. 2008;68:3286-94.
   PubMed     Related articles    Abstract available
   
   
   April 2008
7. MEDINA R , Zaidi SK, Liu CG, Stein JL, et al
   MicroRNAs 221 and 222 bypass quiescence and compromise cell survival.
   Cancer Res. 2008;68:2773-80.
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8. MOLENAAR JJ , Ebus ME, Koster J, van Sluis P, et al
   Cyclin D1 and CDK4 activity contribute to the undifferentiated phenotype in neuroblastoma.
   Cancer Res. 2008;68:2599-609.
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9. BECHER OJ , Hambardzumyan D, Fomchenko EI, Momota H, et al
   Gli activity correlates with tumor grade in platelet-derived growth factor-induced gliomas.
   Cancer Res. 2008;68:2241-9.
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10. SOLOMON DA , Kim JS, Jenkins S, Ressom H, et al
    Identification of p18INK4c as a Tumor Suppressor Gene in Glioblastoma Multiforme.
    Cancer Res. 2008;.
    PubMed     Related articles    Abstract available   Free Full Text
    
    
    March 2008
11. BLAZQUEZ C , Salazar M, Carracedo A, Lorente M, et al
    Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression.
    Cancer Res. 2008;68:1945-52.
    PubMed     Related articles    Abstract available
    
    
    
12. DEY N , Crosswell HE, De P, Parsons R, et al
    The protein phosphatase activity of PTEN regulates SRC family kinases and controls glioma migration.
    Cancer Res. 2008;68:1862-71.
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13. HATTON BA , Villavicencio EH, Tsuchiya KD, Pritchard JI, et al
    The Smo/Smo model: hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread.
    Cancer Res. 2008;68:1768-76.
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14. HEGEDUS B , Banerjee D, Yeh TH, Rothermich S, et al
    Preclinical cancer therapy in a mouse model of neurofibromatosis-1 optic glioma.
    Cancer Res. 2008;68:1520-8.
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15. CHOI BH , Kim CG, Bae YS, Lim Y, et al
    p21 Waf1/Cip1 expression by curcumin in U-87MG human glioma cells: role of early growth response-1 expression.
    Cancer Res. 2008;68:1369-77.
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16. SARKAR D , Park ES, Emdad L, Lee SG, et al
    Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1.
    Cancer Res. 2008;68:1478-84.
    PubMed     Related articles    Abstract available
    
    
    February 2008
17. KARDOSH A , Golden EB, Pyrko P, Uddin J, et al
    Aggravated endoplasmic reticulum stress as a basis for enhanced glioblastoma cell killing by bortezomib in combination with celecoxib or its non-coxib analogue, 2,5-dimethyl-celecoxib.
    Cancer Res. 2008;68:843-51.
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18. COBBS CS , Soroceanu L, Denham S, Zhang W, et al
    Modulation of oncogenic phenotype in human glioma cells by cytomegalovirus IE1-mediated mitogenicity.
    Cancer Res. 2008;68:724-30.
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19. SUSWAM E , Li Y, Zhang X, Gillespie GY, et al
    Tristetraprolin down-regulates interleukin-8 and vascular endothelial growth factor in malignant glioma cells.
    Cancer Res. 2008;68:674-82.
    PubMed     Related articles    Abstract available
    
    
    January 2008
20. LI L , Abdel Fattah E, Cao G, Ren C, et al
    Glioma pathogenesis-related protein 1 exerts tumor suppressor activities through proapoptotic reactive oxygen species-c-Jun-NH2 kinase signaling.
    Cancer Res. 2008;68:434-43.
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21. SARFARAZ S , Adhami VM, Syed DN, Afaq F, et al
    Cannabinoids for cancer treatment: progress and promise.
    Cancer Res. 2008;68:339-42.
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22. CLAUS EB , Park PJ, Carroll R, Chan J, et al
    Specific genes expressed in association with progesterone receptors in meningioma.
    Cancer Res. 2008;68:314-22.
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23. KIM EH , Yoon MJ, Kim SU, Kwon TK, et al
    Arsenic trioxide sensitizes human glioma cells, but not normal astrocytes, to TRAIL-induced apoptosis via CCAAT/enhancer-binding protein homologous protein-dependent DR5 up-regulation.
    Cancer Res. 2008;68:266-75.
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24. MACIAS E , de Marval PL, Senderowicz A, Cullen J, et al
    Expression of CDK4 or CDK2 in mouse oral cavity is retained in adult pituitary with distinct effects on tumorigenesis.
    Cancer Res. 2008;68:162-71.
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    December 2007
25. BATISTA LF , Roos WP, Christmann M, Menck CF, et al
    Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: p53 determines the switch by regulating xpc, ddb2, and DNA double-strand breaks.
    Cancer Res. 2007;67:11886-95.
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26. MASRI J , Bernath A, Martin J, Jo OD, et al
    mTORC2 activity is elevated in gliomas and promotes growth and cell motility via overexpression of rictor.
    Cancer Res. 2007;67:11712-20.
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    November 2007
27. PYRKO P , Kardosh A, Wang W, Xiong W, et al
    HIV-1 Protease Inhibitors Nelfinavir and Atazanavir Induce Malignant Glioma Death by Triggering Endoplasmic Reticulum Stress.
    Cancer Res. 2007;67:10920-10928.
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28. WADHWA L , Hurwitz MY, Chevez-Barrios P, Hurwitz RL, et al
    Treatment of invasive retinoblastoma in a murine model using an oncolytic picornavirus.
    Cancer Res. 2007;67:10653-6.
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29. CHESNOKOVA V , Zonis S, Rubinek T, Yu R, et al
    Senescence mediates pituitary hypoplasia and restrains pituitary tumor growth.
    Cancer Res. 2007;67:10564-72.
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    October 2007
30. PYRKO P , Schonthal AH, Hofman FM, Chen TC, et al
    The Unfolded Protein Response Regulator GRP78/BiP as a Novel Target for Increasing Chemosensitivity in Malignant Gliomas.
    Cancer Res. 2007;67:9809-9816.
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31. HUSSAIN SF , Kong LY, Jordan J, Conrad C, et al
    A novel small molecule inhibitor of signal transducers and activators of transcription 3 reverses immune tolerance in malignant glioma patients.
    Cancer Res. 2007;67:9630-6.
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32. PANNER A , Murray JC, Berger MS, Pieper RO, et al
    Heat Shock Protein 90{alpha} Recruits FLIPS to the Death-Inducing Signaling Complex and Contributes to TRAIL Resistance in Human Glioma.
    Cancer Res. 2007;67:9482-9.
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33. LYONS SA , Chung WJ, Weaver AK, Ogunrinu T, et al
    Autocrine glutamate signaling promotes glioma cell invasion.
    Cancer Res. 2007;67:9463-71.
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34. FULCI G , Dmitrieva N, Gianni D, Fontana EJ, et al
    Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses.
    Cancer Res. 2007;67:9398-406.
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35. CORSTEN MF , Miranda R, Kasmieh R, Krichevsky AM, et al
    MicroRNA-21 Knockdown Disrupts Glioma Growth In vivo and Displays Synergistic Cytotoxicity with Neural Precursor Cell Delivered S-TRAIL in Human Gliomas.
    Cancer Res. 2007;67:8994-9000.
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36. FOIJER F , Delzenne-Goette E, Dekker M, Te Riele H, et al
    In vivo significance of the G2 restriction point.
    Cancer Res. 2007;67:9244-7.
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    September 2007
37. GALARNEAU H , Villeneuve J, Gowing G, Julien JP, et al
    Increased glioma growth in mice depleted of macrophages.
    Cancer Res. 2007;67:8874-81.
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38. LUN XQ , Zhou H, Alain T, Sun B, et al
    Targeting human medulloblastoma: oncolytic virotherapy with myxoma virus is enhanced by rapamycin.
    Cancer Res. 2007;67:8818-27.
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39. WOHLFAHRT ME , Beard BC, Lieber A, Kiem HP, et al
    A Capsid-Modified, Conditionally Replicating Oncolytic Adenovirus Vector Expressing TRAIL Leads to Enhanced Cancer Cell Killing in Human Glioblastoma Models.
    Cancer Res. 2007;67:8783-90.
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40. WARRINGTON NM , Woerner BM, Daginakatte GC, Dasgupta B, et al
    Spatiotemporal Differences in CXCL12 Expression and Cyclic AMP Underlie the Unique Pattern of Optic Glioma Growth in Neurofibromatosis Type 1.
    Cancer Res. 2007;67:8588-95.
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41. SON YG , Kim EH, Kim JY, Kim SU, et al
    Silibinin Sensitizes Human Glioma Cells to TRAIL-Mediated Apoptosis via DR5 Up-regulation and Down-regulation of c-FLIP and Survivin.
    Cancer Res. 2007;67:8274-84.
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42. JARBOE JS , Johnson KR, Choi Y, Lonser RR, et al
    Expression of Interleukin-13 Receptor {alpha}2 in Glioblastoma Multiforme: Implications for Targeted Therapies.
    Cancer Res. 2007;67:7983-6.
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43. KOMINSKY SL , Tyler B, Sosnowski J, Brady K, et al
    Clostridium perfringens Enterotoxin as a Novel-Targeted Therapeutic for Brain Metastasis.
    Cancer Res. 2007;67:7977-82.
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44. FAN QW , Cheng CK, Nicolaides TP, Hackett CS, et al
    A Dual Phosphoinositide-3-Kinase {alpha}/mTOR Inhibitor Cooperates with Blockade of Epidermal Growth Factor Receptor in PTEN-Mutant Glioma.
    Cancer Res. 2007;67:7960-7965.
    PubMed     Related articles    Abstract available
    
    
    August 2007
45. PROVENT P , Benito M, Hiba B, Farion R, et al
    Serial In vivo Spectroscopic Nuclear Magnetic Resonance Imaging of Lactate and Extracellular pH in Rat Gliomas Shows Redistribution of Protons Away from Sites of Glycolysis.
    Cancer Res. 2007;67:7638-45.
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46. JARZYNKA MJ , Hu B, Hui KM, Bar-Joseph I, et al
    ELMO1 and Dock180, a Bipartite Rac1 Guanine Nucleotide Exchange Factor, Promote Human Glioma Cell Invasion.
    Cancer Res. 2007;67:7203-11.
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47. ASA SL , Digiovanni R, Jiang J, Ward ML, et al
    A growth hormone receptor mutation impairs growth hormone autofeedback signaling in pituitary tumors.
    Cancer Res. 2007;67:7505-11.
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48. ARWERT E , Hingtgen S, Figueiredo JL, Bergquist H, et al
    Visualizing the dynamics of EGFR activity and antiglioma therapies in vivo.
    Cancer Res. 2007;67:7335-42.
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    July 2007
49. VEISEH M , Gabikian P, Bahrami SB, Veiseh O, et al
    Tumor paint: a chlorotoxin:Cy5.5 bioconjugate for intraoperative visualization of cancer foci.
    Cancer Res. 2007;67:6882-8.
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50. KARIMI-BUSHERI F , Rasouli-Nia A, Allalunis-Turner J, Weinfeld M, et al
    Human polynucleotide kinase participates in repair of DNA double-strand breaks by nonhomologous end joining but not homologous recombination.
    Cancer Res. 2007;67:6619-25.
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51. KIM EH , Sohn S, Kwon HJ, Kim SU, et al
    Sodium selenite induces superoxide-mediated mitochondrial damage and subsequent autophagic cell death in malignant glioma cells.
    Cancer Res. 2007;67:6314-24.
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52. XU K , Shu HK
    EGFR activation results in enhanced cyclooxygenase-2 expression through p38 mitogen-activated protein kinase-dependent activation of the Sp1/Sp3 transcription factors in human gliomas.
    Cancer Res. 2007;67:6121-9.
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53. SASAKI K , Zhu X, Vasquez C, Nishimura F, et al
    Preferential expression of very late antigen-4 on type 1 CTL cells plays a critical role in trafficking into central nervous system tumors.
    Cancer Res. 2007;67:6451-8.
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54. LANGE K , Kammerer M, Hegi ME, Grotegut S, et al
    Endothelin receptor type B counteracts tenascin-C-induced endothelin receptor type A-dependent focal adhesion and actin stress fiber disorganization.
    Cancer Res. 2007;67:6163-73.
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    June 2007
55. AHMED N , Ratnayake M, Savoldo B, Perlaky L, et al
    Regression of Experimental Medulloblastoma following Transfer of HER2-Specific T Cells.
    Cancer Res. 2007;67:5957-5964.
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56. HUANG J , Hu J, Bian X, Chen K, et al
    Transactivation of the epidermal growth factor receptor by formylpeptide receptor exacerbates the malignant behavior of human glioblastoma cells.
    Cancer Res. 2007;67:5906-13.
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57. PFENNINGER CV , Roschupkina T, Hertwig F, Kottwitz D, et al
    CD133 Is Not Present on Neurogenic Astrocytes in the Adult Subventricular Zone, but on Embryonic Neural Stem Cells, Ependymal Cells, and Glioblastoma Cells.
    Cancer Res. 2007;67:5727-36.
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58. FRENCH PJ , Peeters J, Horsman S, Duijm E, et al
    Identification of differentially regulated splice variants and novel exons in glial brain tumors using exon expression arrays.
    Cancer Res. 2007;67:5635-42.
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59. GILBERTSON RJ , Gutmann DH
    Tumorigenesis in the brain: location, location, location.
    Cancer Res. 2007;67:5579-82.
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60. RAFFAGHELLO L , Nozza P, Morandi F, Camoriano M, et al
    Expression and functional analysis of human leukocyte antigen class I antigen-processing machinery in medulloblastoma.
    Cancer Res. 2007;67:5471-8.
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61. MCCALL TD , Pedone CA, Fults DW
    Apoptosis suppression by somatic cell transfer of bcl-2 promotes sonic hedgehog-dependent medulloblastoma formation in mice.
    Cancer Res. 2007;67:5179-85.
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    May 2007
62. RAO JS , Bhoopathi P, Chetty C, Gujrati M, et al
    MMP-9 Short Interfering RNA Induced Senescence Resulting in Inhibition of Medulloblastoma Growth via p16INK4a and Mitogen-Activated Protein Kinase Pathway.
    Cancer Res. 2007;67:4956-64.
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63. RAMSEY MR , Krishnamurthy J, Pei XH, Torrice C, et al
    Expression of p16Ink4a compensates for p18Ink4c loss in cyclin-dependent kinase 4/6-dependent tumors and tissues.
    Cancer Res. 2007;67:4732-41.
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64. KIMMELMAN J , Nalbantoglu J
    Faithful companions: a proposal for neurooncology trials in pet dogs.
    Cancer Res. 2007;67:4541-4.
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65. JIANG Z , Pore N, Cerniglia GJ, Mick R, et al
    Phosphatase and Tensin Homologue Deficiency in Glioblastoma Confers Resistance to Radiation and Temozolomide that Is Reversed by the Protease Inhibitor Nelfinavir.
    Cancer Res. 2007;67:4467-73.
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66. BEIER D , Hau P, Proescholdt M, Lohmeier A, et al
    CD133+ and CD133- Glioblastoma-Derived Cancer Stem Cells Show Differential Growth Characteristics and Molecular Profiles.
    Cancer Res. 2007;67:4010-5.
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67. PALMIERI D , Bronder JL, Herring JM, Yoneda T, et al
    Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain.
    Cancer Res. 2007;67:4190-8.
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68. OLSON MV , Johnson DG, Jiang H, Xu J, et al
    Transgenic E2F1 expression in the mouse brain induces a human-like bimodal pattern of tumors.
    Cancer Res. 2007;67:4005-9.
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    April 2007
69. TSAI MH , Cook JA, Chandramouli GV, Degraff W, et al
    Gene Expression Profiling of Breast, Prostate, and Glioma Cells following Single versus Fractionated Doses of Radiation.
    Cancer Res. 2007;67:3845-52.
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70. BRADLEY SV , Holland EC, Liu GY, Thomas D, et al
    Huntingtin Interacting Protein 1 Is a Novel Brain Tumor Marker that Associates with Epidermal Growth Factor Receptor.
    Cancer Res. 2007;67:3609-15.
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71. KIM Y , Yoon JW, Xiao X, Dean NM, et al
    Selective down-regulation of glioma-associated oncogene 2 inhibits the proliferation of hepatocellular carcinoma cells.
    Cancer Res. 2007;67:3583-93.
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72. FOLKINS C , Man S, Xu P, Shaked Y, et al
    Anticancer therapies combining antiangiogenic and tumor cell cytotoxic effects reduce the tumor stem-like cell fraction in glioma xenograft tumors.
    Cancer Res. 2007;67:3560-4.
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73. BALAKRISHNAN A , Bleeker FE, Lamba S, Rodolfo M, et al
    Novel Somatic and Germline Mutations in Cancer Candidate Genes in Glioblastoma, Melanoma, and Pancreatic Carcinoma.
    Cancer Res. 2007;67:3545-3550.
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74. ROTH P , Mittelbronn M, Wick W, Meyermann R, et al
    Malignant Glioma Cells Counteract Antitumor Immune Responses through Expression of Lectin-Like Transcript-1.
    Cancer Res. 2007;67:3540-4.
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75. MARTIN R , Carvalho J, Ibeas E, Hernandez M, et al
    Acidic triterpenes compromise growth and survival of astrocytoma cell lines by regulating reactive oxygen species accumulation.
    Cancer Res. 2007;67:3741-51.
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76. SASAI K , Romer JT, Kimura H, Eberhart DE, et al
    Medulloblastomas Derived from Cxcr6 Mutant Mice Respond to Treatment with a Smoothened Inhibitor.
    Cancer Res. 2007;.
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77. PISATI F , Belicchi M, Acerbi F, Marchesi C, et al
    Effect of human skin-derived stem cells on vessel architecture, tumor growth, and tumor invasion in brain tumor animal models.
    Cancer Res. 2007;67:3054-63.
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78. CHAI J , Lu X, Godfrey V, Fletcher C, et al
    Tumor-specific cooperation of retinoblastoma protein family and Snf5 inactivation.
    Cancer Res. 2007;67:3002-9.
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    March 2007
79. ZINDY F , Uziel T, Ayrault O, Calabrese C, et al
    Genetic Alterations in Mouse Medulloblastomas and Generation of Tumors De novo from Primary Cerebellar Granule Neuron Precursors.
    Cancer Res. 2007;67:2676-84.
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    February 2007
80. JACOBS AH , Rueger MA, Winkeler A, Li H, et al
    Imaging-guided gene therapy of experimental gliomas.
    Cancer Res. 2007;67:1706-15.
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81. LAI CP , Bechberger JF, Thompson RJ, Macvicar BA, et al
    Tumor-suppressive effects of pannexin 1 in c6 glioma cells.
    Cancer Res. 2007;67:1545-54.
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82. CHEN EI , Hewel J, Krueger JS, Tiraby C, et al
    Adaptation of energy metabolism in breast cancer brain metastases.
    Cancer Res. 2007;67:1472-86.
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83. SHARMA MK , Mansur DB, Reifenberger G, Perry A, et al
    Distinct genetic signatures among pilocytic astrocytomas relate to their brain region origin.
    Cancer Res. 2007;67:890-900.
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    January 2007
84. YANG L , Jackson E, Woerner BM, Perry A, et al
    Blocking CXCR4-mediated cyclic AMP suppression inhibits brain tumor growth in vivo.
    Cancer Res. 2007;67:651-8.
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85. YU Y , Jiang X, Schoch BS, Carroll RS, et al
    Aberrant splicing of cyclin-dependent kinase-associated protein phosphatase KAP increases proliferation and migration in glioblastoma.
    Cancer Res. 2007;67:130-8.
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    December 2006
86. KANG SH , Cho HT, Devi S, Zhang Z, et al
    Antitumor effect of 2-methoxyestradiol in a rat orthotopic brain tumor model.
    Cancer Res. 2006;66:11991-7.
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87. LU W , Sun Q, Wan J, She Z, et al
    Cationic Albumin-Conjugated Pegylated Nanoparticles Allow Gene Delivery into Brain Tumors via Intravenous Administration.
    Cancer Res. 2006;66:11878-87.
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88. ALLEN C , Vongpunsawad S, Nakamura T, James CD, et al
    Retargeted Oncolytic Measles Strains Entering via the EGFRvIII Receptor Maintain Significant Antitumor Activity against Gliomas with Increased Tumor Specificity.
    Cancer Res. 2006;66:11840-50.
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89. SARKAR S , Nuttall RK, Liu S, Edwards DR, et al
    Tenascin-C Stimulates Glioma Cell Invasion through Matrix Metalloproteinase-12.
    Cancer Res. 2006;66:11771-80.
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90. SANTRA M , Zhang X, Santra S, Jiang F, et al
    Ectopic doublecortin gene expression suppresses the malignant phenotype in glioblastoma cells.
    Cancer Res. 2006;66:11726-35.
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91. GOLDBERG L , Kloog Y
    A Ras Inhibitor Tilts the Balance between Rac and Rho and Blocks Phosphatidylinositol 3-Kinase-Dependent Glioblastoma Cell Migration.
    Cancer Res. 2006;66:11709-17.
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92. BARZ T , Hoffmann A, Panhuysen M, Spengler D, et al
    Peroxisome proliferator-activated receptor gamma is a Zac target gene mediating Zac antiproliferation.
    Cancer Res. 2006;66:11975-82.
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93. MORGAN MT , Nakanishi Y, Kroll DJ, Griset AP, et al
    Dendrimer-encapsulated camptothecins: increased solubility, cellular uptake, and cellular retention affords enhanced anticancer activity in vitro.
    Cancer Res. 2006;66:11913-21.
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94. HORVATH A , Giatzakis C, Robinson-White A, Boikos S, et al
    Adrenal hyperplasia and adenomas are associated with inhibition of phosphodiesterase 11A in carriers of PDE11A sequence variants that are frequent in the population.
    Cancer Res. 2006;66:11571-5.
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