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The Medical Article of the Year 2008:
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78.
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Articles published in Clin Cancer Res

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    July 2008
  1. DE HAAS T , Hasselt N, Troost D, Caron H, et al
    Molecular Risk Stratification of Medulloblastoma Patients Based on Immunohistochemical Analysis of MYC, LDHB, and CCNB1 Expression.
    Clin Cancer Res. 2008;14:4154-60.
    PubMed     Related articles    Abstract available


  2. NAM DH , Jeon HM, Kim S, Kim MH, et al
    Activation of Notch Signaling in a Xenograft Model of Brain Metastasis.
    Clin Cancer Res. 2008;14:4059-4066.
    PubMed     Related articles    Abstract available


  3. HUANG J , Grotzer MA, Watanabe T, Hewer E, et al
    Mutations in the nijmegen breakage syndrome gene in medulloblastomas.
    Clin Cancer Res. 2008;14:4053-8.
    PubMed     Related articles    Abstract available


    June 2008
  4. YIN D , Wang X, Konda BM, Ong JM, et al
    Increase in brain tumor permeability in glioma-bearing rats with nitric oxide donors.
    Clin Cancer Res. 2008;14:4002-9.
    PubMed     Related articles    Abstract available


  5. YANG L , Clarke MJ, Carlson BL, Mladek AC, et al
    PTEN Loss Does Not Predict for Response to RAD001 (Everolimus) in a Glioblastoma Orthotopic Xenograft Test Panel.
    Clin Cancer Res. 2008;14:3993-4001.
    PubMed     Related articles    Abstract available


  6. LAZOVIC J , Jensen MC, Ferkassian E, Aguilar B, et al
    Imaging Immune Response In vivo: Cytolytic Action of Genetically Altered T Cells Directed to Glioblastoma Multiforme.
    Clin Cancer Res. 2008;14:3832-3839.
    PubMed     Related articles    Abstract available


  7. WEI LH , Su H, Hildebrandt IJ, Phelps ME, et al
    Changes in tumor metabolism as readout for Mammalian target of rapamycin kinase inhibition by rapamycin in glioblastoma.
    Clin Cancer Res. 2008;14:3416-26.
    PubMed     Related articles    Abstract available


  8. THORARINSDOTTIR HK , Santi M, McCarter R, Rushing EJ, et al
    Protein Expression of Platelet-Derived Growth Factor Receptor Correlates with Malignant Histology and PTEN with Survival in Childhood Gliomas.
    Clin Cancer Res. 2008;14:3386-94.
    PubMed     Related articles    Abstract available


    May 2008
  9. EGLER V , Korur S, Failly M, Boulay JL, et al
    Histone deacetylase inhibition and blockade of the glycolytic pathway synergistically induce glioblastoma cell death.
    Clin Cancer Res. 2008;14:3132-40.
    PubMed     Related articles    Abstract available


  10. DE VLEESCHOUWER S , Fieuws S, Rutkowski S, Van Calenbergh F, et al
    Postoperative adjuvant dendritic cell-based immunotherapy in patients with relapsed glioblastoma multiforme.
    Clin Cancer Res. 2008;14:3098-104.
    PubMed     Related articles    Abstract available


  11. REDDY SP , Britto R, Vinnakota K, Aparna H, et al
    Novel Glioblastoma Markers with Diagnostic and Prognostic Value Identified through Transcriptome Analysis.
    Clin Cancer Res. 2008;14:2978-87.
    PubMed     Related articles    Abstract available


  12. SARKARIA JN , Kitange GJ, James CD, Plummer R, et al
    Mechanisms of chemoresistance to alkylating agents in malignant glioma.
    Clin Cancer Res. 2008;14:2900-8.
    PubMed     Related articles    Abstract available


  13. SPENCE AM , Muzi M, Swanson KR, O'Sullivan F, et al
    Regional Hypoxia in Glioblastoma Multiforme Quantified with [18F]Fluoromisonidazole Positron Emission Tomography before Radiotherapy: Correlation with Time to Progression and Survival.
    Clin Cancer Res. 2008;14:2623-30.
    PubMed     Related articles    Abstract available


    April 2008
  14. SMITH ER , Zurakowski D, Saad A, Scott RM, et al
    Urinary biomarkers predict brain tumor presence and response to therapy.
    Clin Cancer Res. 2008;14:2378-86.
    PubMed     Related articles    Abstract available


  15. ULLRICH R , Backes H, Li H, Kracht L, et al
    Glioma proliferation as assessed by 3'-fluoro-3'-deoxy-L-thymidine positron emission tomography in patients with newly diagnosed high-grade glioma.
    Clin Cancer Res. 2008;14:2049-55.
    PubMed     Related articles    Abstract available


  16. ZHU X , Asa SL, Ezzat S
    Fibroblast growth factor 2 and estrogen control the balance of histone 3 modifications targeting MAGE-A3 in pituitary neoplasia.
    Clin Cancer Res. 2008;14:1984-96.
    PubMed     Related articles    Abstract available


    March 2008
  17. GILG AG , Tye SL, Tolliver LB, Wheeler WG, et al
    Targeting hyaluronan interactions in malignant gliomas and their drug-resistant multipotent progenitors.
    Clin Cancer Res. 2008;14:1804-13.
    PubMed     Related articles    Abstract available


  18. HUSZTHY PC , Goplen D, Thorsen F, Immervoll H, et al
    Oncolytic herpes simplex virus type-1 therapy in a highly infiltrative animal model of human glioblastoma.
    Clin Cancer Res. 2008;14:1571-80.
    PubMed     Related articles    Abstract available


  19. CHIAPPORI AA , Haura E, Rodriguez FA, Boulware D, et al
    Phase I/II Study of Atrasentan, an Endothelin A Receptor Antagonist, in Combination with Paclitaxel and Carboplatin as First-Line Therapy in Advanced Non-Small Cell Lung Cancer.
    Clin Cancer Res. 2008;14:1464-9.
    PubMed     Related articles    Abstract available


    February 2008
  20. GURURANGAN S , Turner CD, Stewart CF, O'Shaughnessy M, et al
    Phase I Trial of VNP40101M (Cloretazine) in Children with Recurrent Brain Tumors: A Pediatric Brain Tumor Consortium Study.
    Clin Cancer Res. 2008;14:1124-30.
    PubMed     Related articles    Abstract available


  21. ROSSI A , Caracciolo V, Russo G, Reiss K, et al
    Medulloblastoma: From Molecular Pathology to Therapy.
    Clin Cancer Res. 2008;14:971-976.
    PubMed     Related articles    Abstract available


  22. BRANDES AA , Franceschi E, Tosoni A, Hegi ME, et al
    Epidermal growth factor receptor inhibitors in neuro-oncology: hopes and disappointments.
    Clin Cancer Res. 2008;14:957-60.
    PubMed     Related articles    Abstract available


  23. YANG W , Wu G, Barth RF, Swindall MR, et al
    Molecular Targeting and Treatment of Composite EGFR and EGFRvIII-Positive Gliomas Using Boronated Monoclonal Antibodies.
    Clin Cancer Res. 2008;14:883-91.
    PubMed     Related articles    Abstract available


  24. KIL WJ , Cerna D, Burgan WE, Beam K, et al
    In vitro and in vivo radiosensitization induced by the DNA methylating agent temozolomide.
    Clin Cancer Res. 2008;14:931-8.
    PubMed     Related articles    Abstract available


    January 2008
  25. YOSHIMOTO K , Dang J, Zhu S, Nathanson D, et al
    Development of a Real-time RT-PCR Assay for Detecting EGFRvIII in Glioblastoma Samples.
    Clin Cancer Res. 2008;14:488-493.
    PubMed     Related articles    Abstract available


  26. GOW CH , Chien CR, Chang YL, Chiu YH, et al
    Radiotherapy in lung adenocarcinoma with brain metastases: effects of activating epidermal growth factor receptor mutations on clinical response.
    Clin Cancer Res. 2008;14:162-8.
    PubMed     Related articles    Abstract available


  27. HUTTERER M , Knyazev P, Abate A, Reschke M, et al
    Axl and growth arrest specific gene 6 are frequently overexpressed in human gliomas and predict poor prognosis in patients with glioblastoma multiforme.
    Clin Cancer Res. 2008;14:130-8.
    PubMed     Related articles    Abstract available


  28. ZEPPERNICK F , Ahmadi R, Campos B, Dictus C, et al
    Stem Cell Marker CD133 Affects Clinical Outcome in Glioma Patients.
    Clin Cancer Res. 2008;14:123-9.
    PubMed     Related articles    Abstract available


  29. KORSISAARI N , Ross J, Wu X, Kowanetz M, et al
    Blocking vascular endothelial growth factor-A inhibits the growth of pituitary adenomas and lowers serum prolactin level in a mouse model of multiple endocrine neoplasia type 1.
    Clin Cancer Res. 2008;14:249-58.
    PubMed     Related articles    Abstract available


  30. WYKOSKY J , Gibo DM, Stanton C, Debinski W, et al
    Interleukin-13 receptor alpha 2, EphA2, and Fos-related antigen 1 as molecular denominators of high-grade astrocytomas and specific targets for combinatorial therapy.
    Clin Cancer Res. 2008;14:199-208.
    PubMed     Related articles    Abstract available


    December 2007
  31. LAMFERS ML , Idema S, Bosscher L, Heukelom S, et al
    Differential Effects of Combined Ad5-{Delta}24RGD and Radiation Therapy in In vitro versus In vivo Models of Malignant Glioma.
    Clin Cancer Res. 2007;13:7451-7458.
    PubMed     Related articles    Abstract available


  32. KUHN JG , Chang SM, Wen PY, Cloughesy TF, et al
    Pharmacokinetic and tumor distribution characteristics of temsirolimus in patients with recurrent malignant glioma.
    Clin Cancer Res. 2007;13:7401-6.
    PubMed     Related articles    Abstract available


  33. SHIRAHATA M , Iwao-Koizumi K, Saito S, Ueno N, et al
    Gene expression-based molecular diagnostic system for malignant gliomas is superior to histological diagnosis.
    Clin Cancer Res. 2007;13:7341-56.
    PubMed     Related articles    Abstract available


  34. JIANG X , Lu X, Liu R, Zhang F, et al
    HLA Tetramer Based Artificial Antigen-Presenting Cells Efficiently Stimulate CTLs Specific for Malignant Glioma.
    Clin Cancer Res. 2007;13:7329-34.
    PubMed     Related articles    Abstract available


  35. LIU C , Sarkaria JN, Petell CA, Paraskevakou G, et al
    Combination of Measles Virus Virotherapy and Radiation Therapy Has Synergistic Activity in the Treatment of Glioblastoma Multiforme.
    Clin Cancer Res. 2007;13:7155-7165.
    PubMed     Related articles    Abstract available


  36. LOGHIN ME , Prados MD, Wen P, Junck L, et al
    Phase I study of temozolomide and irinotecan for recurrent malignant gliomas in patients receiving enzyme-inducing antiepileptic drugs: a north american brain tumor consortium study.
    Clin Cancer Res. 2007;13:7133-8.
    PubMed     Related articles    Abstract available


  37. LO KC , Ma C, Bundy BN, Pomeroy SL, et al
    Gain of 1q is a potential univariate negative prognostic marker for survival in medulloblastoma.
    Clin Cancer Res. 2007;13:7022-8.
    PubMed     Related articles    Abstract available


  38. MANGIOLA A , Lama G, Giannitelli C, De Bonis P, et al
    Stem Cell Marker Nestin and c-Jun NH2-Terminal Kinases in Tumor and Peritumor Areas of Glioblastoma Multiforme: Possible Prognostic Implications.
    Clin Cancer Res. 2007;13:6970-6977.
    PubMed     Related articles    Abstract available


  39. FINE HA , Kim L, Albert PS, Duic JP, et al
    A phase I trial of lenalidomide in patients with recurrent primary central nervous system tumors.
    Clin Cancer Res. 2007;13:7101-6.
    PubMed     Related articles    Abstract available


  40. WELLER M , Berger H, Hartmann C, Schramm J, et al
    Combined 1p/19q loss in oligodendroglial tumors: predictive or prognostic biomarker?
    Clin Cancer Res. 2007;13:6933-7.
    PubMed     Related articles    Abstract available


    November 2007
  41. MILETIC H , Fischer YH, Giroglou T, Rueger MA, et al
    Normal Brain Cells Contribute to the Bystander Effect in Suicide Gene Therapy of Malignant Glioma.
    Clin Cancer Res. 2007;13:6761-6768.
    PubMed     Related articles    Abstract available


  42. BRONISCER A , Gururangan S, Macdonald TJ, Goldman S, et al
    Phase I Trial of Single-Dose Temozolomide and Continuous Administration of O6-Benzylguanine in Children with Brain Tumors: a Pediatric Brain Tumor Consortium Report.
    Clin Cancer Res. 2007;13:6712-6718.
    PubMed     Related articles    Abstract available


  43. AOKI H , Yokoyama T, Fujiwara K, Tari AM, et al
    Phosphorylated Pak1 Level in the Cytoplasm Correlates with Shorter Survival Time in Patients with Glioblastoma.
    Clin Cancer Res. 2007;13:6603-6609.
    PubMed     Related articles    Abstract available


  44. KOSCHNY R , Sykora J, Walczak H, Ganten TM, et al
    Bortezomib-Mediated Up-Regulation of TRAIL-R1 and TRAIL-R2 Is Not Necessary for but Contributes to Sensitization of Primary Human Glioma Cells to TRAIL.
    Clin Cancer Res. 2007;13:6541-6542.
    PubMed     Related articles   


  45. HAQUE T , Faury D, Albrecht S, Lopez-Aguilar E, et al
    Gene Expression Profiling from Formalin-Fixed Paraffin-Embedded Tumors of Pediatric Glioblastoma.
    Clin Cancer Res. 2007;13:6284-6292.
    PubMed     Related articles    Abstract available


  46. KYRITSIS AP , Tachmazoglou F, Rao JS, Puduvalli VK, et al
    Bortezomib sensitizes human astrocytoma cells to tumor necrosis factor related apoptosis-inducing ligand induced apoptosis.
    Clin Cancer Res. 2007;13:6540-1.
    PubMed     Related articles   


    October 2007
  47. YAMINI B , Yu X, Pytel P, Galanopoulos N, et al
    Adenovirally delivered tumor necrosis factor-alpha improves the antiglioma efficacy of concomitant radiation and temozolomide therapy.
    Clin Cancer Res. 2007;13:6217-23.
    PubMed     Related articles    Abstract available


  48. IKEGAKI N , Gotoh T, Kung B, Riceberg JS, et al
    De novo identification of MIZ-1 (ZBTB17) encoding a MYC-interacting zinc-finger protein as a new favorable neuroblastoma gene.
    Clin Cancer Res. 2007;13:6001-9.
    PubMed     Related articles    Abstract available


    August 2007
  49. ROUSSEAU J , Boudou C, Barth RF, Balosso J, et al
    Enhanced Survival and Cure of F98 Glioma Bearing Rats following Intracerebral Delivery of Carboplatin in Combination with Photon Irradiation.
    Clin Cancer Res. 2007;.
    PubMed     Related articles    Abstract available   Free Full Text


    July 2007
  50. ZHOU Q , Guo P, Kruh GD, Vicini P, et al
    Predicting human tumor drug concentrations from a preclinical pharmacokinetic model of temozolomide brain disposition.
    Clin Cancer Res. 2007;13:4271-9.
    PubMed     Related articles    Abstract available


  51. GONDI CS , Lakka SS, Dinh DH, Olivero WC, et al
    Intraperitoneal injection of a hairpin RNA-expressing plasmid targeting urokinase-type plasminogen activator (uPA) receptor and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice.
    Clin Cancer Res. 2007;13:4051-60.
    PubMed     Related articles    Abstract available


  52. KOBAYASHI T , Masumoto J, Tada T, Nomiyama T, et al
    Prognostic significance of the immunohistochemical staining of cleaved caspase-3, an activated form of caspase-3, in gliomas.
    Clin Cancer Res. 2007;13:3868-74.
    PubMed     Related articles    Abstract available


    June 2007
  53. EWEND MG , Brem S, Gilbert M, Goodkin R, et al
    Treatment of single brain metastasis with resection, intracavity carmustine polymer wafers, and radiation therapy is safe and provides excellent local control.
    Clin Cancer Res. 2007;13:3637-41.
    PubMed     Related articles    Abstract available


  54. GEORGE J , Gondi CS, Dinh DH, Gujrati M, et al
    Restoration of tissue factor pathway inhibitor-2 in a human glioblastoma cell line triggers caspase-mediated pathway and apoptosis.
    Clin Cancer Res. 2007;13:3507-17.
    PubMed     Related articles    Abstract available


  55. BARNETT JA , Urbauer DL, Murray GI, Fuller GN, et al
    Cytochrome P450 1B1 expression in glial cell tumors: an immunotherapeutic target.
    Clin Cancer Res. 2007;13:3559-67.
    PubMed     Related articles    Abstract available


  56. KOSCHNY R , Holland H, Sykora J, Haas TL, et al
    Bortezomib sensitizes primary human astrocytoma cells of WHO grades I to IV for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.
    Clin Cancer Res. 2007;13:3403-12.
    PubMed     Related articles    Abstract available


    May 2007
  57. MCCONVILLE P , Hambardzumyan D, Moody JB, Leopold WR, et al
    Magnetic resonance imaging determination of tumor grade and early response to temozolomide in a genetically engineered mouse model of glioma.
    Clin Cancer Res. 2007;13:2897-904.
    PubMed     Related articles    Abstract available


  58. RUTKOWSKI S , von Bueren A, von Hoff K, Hartmann W, et al
    Prognostic Relevance of Clinical and Biological Risk Factors in Childhood Medulloblastoma: Results of Patients Treated in the Prospective Multicenter Trial HIT'91.
    Clin Cancer Res. 2007;13:2651-7.
    PubMed     Related articles    Abstract available


  59. COSTA BM , Ferreira P, Costa S, Canedo P, et al
    Association between Functional EGF+61 Polymorphism and Glioma Risk.
    Clin Cancer Res. 2007;13:2621-6.
    PubMed     Related articles    Abstract available


  60. EOLI M , Menghi F, Bruzzone MG, De Simone T, et al
    Methylation of O6-Methylguanine DNA Methyltransferase and Loss of Heterozygosity on 19q and/or 17p Are Overlapping Features of Secondary Glioblastomas with Prolonged Survival.
    Clin Cancer Res. 2007;13:2606-13.
    PubMed     Related articles    Abstract available


  61. CARLSON MR , Pope WB, Horvath S, Braunstein JG, et al
    Relationship between Survival and Edema in Malignant Gliomas: Role of Vascular Endothelial Growth Factor and Neuronal Pentraxin 2.
    Clin Cancer Res. 2007;13:2592-2598.
    PubMed     Related articles    Abstract available


  62. FEDELE M , De Martino I, Pivonello R, Ciarmiello A, et al
    SOM230, a new somatostatin analogue, is highly effective in the therapy of growth hormone/prolactin-secreting pituitary adenomas.
    Clin Cancer Res. 2007;13:2738-44.
    PubMed     Related articles    Abstract available


    April 2007
  63. GILLESPIE DL , Whang K, Ragel BT, Flynn JR, et al
    Silencing of Hypoxia Inducible Factor-1{alpha} by RNA Interference Attenuates Human Glioma Cell Growth In vivo.
    Clin Cancer Res. 2007;13:2441-8.
    PubMed     Related articles    Abstract available


  64. ZHOU H , Miki R, Eeva M, Fike FM, et al
    Reciprocal Regulation of SOCS 1 and SOCS3 Enhances Resistance to Ionizing Radiation in Glioblastoma Multiforme.
    Clin Cancer Res. 2007;13:2344-2353.
    PubMed     Related articles    Abstract available


  65. SOUSSAIN C , Muldoon LL, Varallyay C, Jahnke K, et al
    Characterization and magnetic resonance imaging of a rat model of human B-cell central nervous system lymphoma.
    Clin Cancer Res. 2007;13:2504-11.
    PubMed     Related articles    Abstract available


  66. LI L , Gondi CS, Dinh DH, Olivero WC, et al
    Transfection with Anti-p65 Intrabody Suppresses Invasion and Angiogenesis in Glioma Cells by Blocking Nuclear Factor-{kappa}B Transcriptional Activity.
    Clin Cancer Res. 2007;13:2178-90.
    PubMed     Related articles    Abstract available


  67. FECCI PE , Ochiai H, Mitchell DA, Grossi PM, et al
    Systemic CTLA-4 Blockade Ameliorates Glioma-Induced Changes to the CD4+ T Cell Compartment without Affecting Regulatory T-Cell Function.
    Clin Cancer Res. 2007;13:2158-67.
    PubMed     Related articles    Abstract available


  68. CAHILL DP , Levine KK, Betensky RA, Codd PJ, et al
    Loss of the Mismatch Repair Protein MSH6 in Human Glioblastomas Is Associated with Tumor Progression during Temozolomide Treatment.
    Clin Cancer Res. 2007;13:2038-45.
    PubMed     Related articles    Abstract available


    March 2007
  69. JOHNS TG , Perera RM, Vernes SC, Vitali AA, et al
    The Efficacy of Epidermal Growth Factor Receptor-Specific Antibodies against Glioma Xenografts Is Influenced by Receptor Levels, Activation Status, and Heterodimerization.
    Clin Cancer Res. 2007;13:1911-1925.
    PubMed     Related articles    Abstract available


  70. PATEL RR , Mehta MP
    Targeted therapy for brain metastases: improving the therapeutic ratio.
    Clin Cancer Res. 2007;13:1675-83.
    PubMed     Related articles    Abstract available


  71. LIN NU , Winer EP
    Brain Metastases: The HER2 Paradigm.
    Clin Cancer Res. 2007;13:1648-55.
    PubMed     Related articles    Abstract available


  72. MAYER M
    A patient perspective on brain metastases in breast cancer.
    Clin Cancer Res. 2007;13:1623-4.
    PubMed     Related articles   


  73. DEEKEN JF , Loscher W
    The blood-brain barrier and cancer: transporters, treatment, and Trojan horses.
    Clin Cancer Res. 2007;13:1663-74.
    PubMed     Related articles    Abstract available


  74. PALMIERI D , Chambers AF, Felding-Habermann B, Huang S, et al
    The biology of metastasis to a sanctuary site.
    Clin Cancer Res. 2007;13:1656-62.
    PubMed     Related articles    Abstract available


  75. ARAGON-CHING JB , Zujewski JA
    CNS metastasis: an old problem in a new guise.
    Clin Cancer Res. 2007;13:1644-7.
    PubMed     Related articles    Abstract available


  76. BRONISCER A , Panetta JC, O'Shaughnessy M, Fraga C, et al
    Plasma and cerebrospinal fluid pharmacokinetics of erlotinib and its active metabolite OSI-420.
    Clin Cancer Res. 2007;13:1511-5.
    PubMed     Related articles    Abstract available


  77. MARTIN DT , Gendron RL, Jarzembowski JA, Perry A, et al
    Tubedown expression correlates with the differentiation status and aggressiveness of neuroblastic tumors.
    Clin Cancer Res. 2007;13:1480-7.
    PubMed     Related articles    Abstract available


  78. SCHRAMM A , Vandesompele J, Schulte JH, Dreesmann S, et al
    Translating expression profiling into a clinically feasible test to predict neuroblastoma outcome.
    Clin Cancer Res. 2007;13:1459-65.
    PubMed     Related articles    Abstract available


  79. LAVON I , Zrihan D, Zelikovitch B, Fellig Y, et al
    Longitudinal assessment of genetic and epigenetic markers in oligodendrogliomas.
    Clin Cancer Res. 2007;13:1429-37.
    PubMed     Related articles    Abstract available


    February 2007
  80. WU G , Yang W, Barth RF, Kawabata S, et al
    Molecular targeting and treatment of an epidermal growth factor receptor-positive glioma using boronated cetuximab.
    Clin Cancer Res. 2007;13:1260-8.
    PubMed     Related articles    Abstract available


  81. VREDENBURGH JJ , Desjardins A, Herndon JE 2nd, Dowell JM, et al
    Phase II Trial of Bevacizumab and Irinotecan in Recurrent Malignant Glioma.
    Clin Cancer Res. 2007;13:1253-9.
    PubMed     Related articles    Abstract available


  82. YIN D , Ong JM, Hu J, Desmond JC, et al
    Suberoylanilide Hydroxamic Acid, a Histone Deacetylase Inhibitor: Effects on Gene Expression and Growth of Glioma Cells In vitro and In vivo.
    Clin Cancer Res. 2007;13:1045-52.
    PubMed     Related articles    Abstract available


    January 2007
  83. BOBOLA MS , Varadarajan S, Smith NW, Goff RD, et al
    Human glioma cell sensitivity to the sequence-specific alkylating agent methyl-lexitropsin.
    Clin Cancer Res. 2007;13:612-20.
    PubMed     Related articles    Abstract available


  84. ZHANG JG , Eguchi J, Kruse CA, Gomez GG, et al
    Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics.
    Clin Cancer Res. 2007;13:566-75.
    PubMed     Related articles    Abstract available


  85. MELLINGHOFF IK , Cloughesy TF, Mischel PS
    PTEN-mediated resistance to epidermal growth factor receptor kinase inhibitors.
    Clin Cancer Res. 2007;13.
    PubMed     Related articles    Abstract available


  86. WRENSCH M , McMillan A, Wiencke J, Wiemels J, et al
    Nonsynonymous coding single-nucleotide polymorphisms spanning the genome in relation to glioblastoma survival and age at diagnosis.
    Clin Cancer Res. 2007;13:197-205.
    PubMed     Related articles    Abstract available


  87. YOO H , Baia GS, Smith JS, McDermott MW, et al
    Expression of the hypoxia marker carbonic anhydrase 9 is associated with anaplastic phenotypes in meningiomas.
    Clin Cancer Res. 2007;13:68-75.
    PubMed     Related articles    Abstract available


    December 2006
  88. LEARN CA , Fecci PE, Schmittling RJ, Xie W, et al
    Profiling of CD4+, CD8+, and CD4+CD25+CD45RO+FoxP3+ T Cells in Patients with Malignant Glioma Reveals Differential Expression of the Immunologic Transcriptome Compared with T Cells from Healthy Volunteers.
    Clin Cancer Res. 2006;12:7306-15.
    PubMed     Related articles    Abstract available


  89. NICHOLAS MK , Lukas RV, Jafri NF, Faoro L, et al
    Epidermal growth factor receptor-mediated signal transduction in the development and therapy of gliomas.
    Clin Cancer Res. 2006;12:7261-70.
    PubMed     Related articles    Abstract available


  90. WEBER A , Starke S, Bergmann E, Christiansen H, et al
    The coamplification pattern of the MYCN amplicon is an invariable attribute of most MYCN-amplified human neuroblastomas.
    Clin Cancer Res. 2006;12:7316-21.
    PubMed     Related articles    Abstract available


  91. ROSELL R , Taron M, Reguart N, Isla D, et al
    Epidermal growth factor receptor activation: how exon 19 and 21 mutations changed our understanding of the pathway.
    Clin Cancer Res. 2006;12:7222-31.
    PubMed     Related articles    Abstract available


  92. YAMAMOTO J , Yamamoto S, Hirano T, Li S, et al
    Monitoring of singlet oxygen is useful for predicting the photodynamic effects in the treatment for experimental glioma.
    Clin Cancer Res. 2006;12:7132-9.
    PubMed     Related articles    Abstract available   Free Full Text


    November 2006
  93. REDJAL N , Chan JA, Segal RA, Kung AL, et al
    CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas.
    Clin Cancer Res. 2006;12:6765-71.
    PubMed     Related articles    Abstract available


  94. REDDY GR , Bhojani MS, McConville P, Moody J, et al
    Vascular targeted nanoparticles for imaging and treatment of brain tumors.
    Clin Cancer Res. 2006;12:6677-86.
    PubMed     Related articles    Abstract available


  95. LIU TC , Zhang T, Fukuhara H, Kuroda T, et al
    Dominant-Negative Fibroblast Growth Factor Receptor Expression Enhances Antitumoral Potency of Oncolytic Herpes Simplex Virus in Neural Tumors.
    Clin Cancer Res. 2006;12:6791-6799.
    PubMed     Related articles    Abstract available


  96. TANNO B , Mancini C, Vitali R, Mancuso M, et al
    Down-regulation of insulin-like growth factor I receptor activity by NVP-AEW541 has an antitumor effect on neuroblastoma cells in vitro and in vivo.
    Clin Cancer Res. 2006;12:6772-80.
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  97. TSUDA N , Ishiyama S, Li Y, Ioannides CG, et al
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    Molecular Targeting and Treatment of EGFRvIII-Positive Gliomas Using Boronated Monoclonal Antibody L8A4.
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    May 2006
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