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  Neoplasms of the CNS

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Articles published in J Clin Oncol

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Single Articles


    May 2017
  1. CHALMERS A, Akerley W
    Retrospective, Multi-Institutional Analysis of Sequential Treatment of Brain Metastases in Treatment-Naive, Epidermal Growth Factor Receptor-Mutated Non-Small-Cell Lung Cancer Should Not Define the Standard of Practice.
    J Clin Oncol. 2017 May 8:JCO2017727255. doi: 10.1200/JCO.2017.72.7255.
    PubMed     Text format    


    March 2017
  2. BOWERS DC, Moskowitz CS, Chou JF, Mazewski CM, et al
    Morbidity and Mortality Associated With Meningioma After Cranial Radiotherapy: A Report From the Childhood Cancer Survivor Study.
    J Clin Oncol. 2017 Mar 24:JCO2016701896. doi: 10.1200/JCO.2016.70.1896.
    PubMed     Text format     Abstract available


    January 2017
  3. MAGNUSON WJ, Lester-Coll NH, Wu AJ, Yang TJ, et al
    Management of Brain Metastases in Tyrosine Kinase Inhibitor-Naive Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer: A Retrospective Multi-Institutional Analysis.
    J Clin Oncol. 2017 Jan 23:JCO2016697144. doi: 10.1200/JCO.2016.69.7144.
    PubMed     Text format     Abstract available


  4. ZHOU L, Deng L, Lu Y
    Epidermal Growth Factor Receptor Mutations in Non-Small-Cell Lung Cancer With Brain Metastasis: Can Up-Front Radiation Therapy Be Deferred or Withheld?
    J Clin Oncol. 2017 Jan 23:JCO2016715706. doi: 10.1200/JCO.2016.71.5706.
    PubMed     Text format    


    December 2016
  5. MOLITORIS JK, Edelman MJ, Regine WF, Feigenberg SJ, et al
    Whole-Brain Radiation in the Treatment of Brain Metastases in ALK-Positive Non-Small-Cell Lung Cancer.
    J Clin Oncol. 2016 Dec 28:JCO2016697227.
    PubMed     Text format    


  6. CLEMENT SC, Schouten-van Meeteren AY, Boot AM, Claahsen-van der Grinten HL, et al
    Prevalence and Risk Factors of Early Endocrine Disorders in Childhood Brain Tumor Survivors: A Nationwide, Multicenter Study.
    J Clin Oncol. 2016;34:4362-4370.
    PubMed     Text format     Abstract available


  7. CLOUGHESY T, Finocchiaro G, Belda-Iniesta C, Recht L, et al
    Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase II Study of Onartuzumab Plus Bevacizumab Versus Placebo Plus Bevacizumab in Patients With Recurrent Glioblastoma: Efficacy, Safety, and Hepatocyte Growth Factor and O6-Methylguanine-DNA M
    J Clin Oncol. 2016 Dec 5:JCO2015647685.
    PubMed     Text format     Abstract available


  8. WARDAK Z, Choy H
    Improving Treatment Options for Brain Metastases From ALK-Positive Non-Small-Cell Lung Cancer.
    J Clin Oncol. 2016;34:4064-4065.
    PubMed     Text format    


  9. VON BUEREN AO, Kortmann RD, von Hoff K, Friedrich C, et al
    Treatment of Children and Adolescents With Metastatic Medulloblastoma and Prognostic Relevance of Clinical and Biologic Parameters.
    J Clin Oncol. 2016;34:4151-4160.
    PubMed     Text format     Abstract available


    November 2016
  10. SULMAN EP, Ismaila N, Armstrong TS, Tsien C, et al
    Radiation Therapy for Glioblastoma: American Society of Clinical Oncology Clinical Practice Guideline Endorsement of the American Society for Radiation Oncology Guideline.
    J Clin Oncol. 2016 Nov 28:JCO2016707562.
    PubMed     Text format     Abstract available


  11. CHOI C, Raisanen JM, Ganji SK, Zhang S, et al
    Prospective Longitudinal Analysis of 2-Hydroxyglutarate Magnetic Resonance Spectroscopy Identifies Broad Clinical Utility for the Management of Patients With IDH-Mutant Glioma.
    J Clin Oncol. 2016;34:4030-4039.
    PubMed     Text format     Abstract available


    August 2016
  12. LASSALETTA A, Scheinemann K, Zelcer SM, Hukin J, et al
    Phase II Weekly Vinblastine for Chemotherapy-Naive Children With Progressive Low-Grade Glioma: A Canadian Pediatric Brain Tumor Consortium Study.
    J Clin Oncol. 2016 Aug 29. pii: JCO681585.
    PubMed     Text format     Abstract available


  13. MOXON-EMRE I, Taylor MD, Bouffet E, Hardy K, et al
    Intellectual Outcome in Molecular Subgroups of Medulloblastoma.
    J Clin Oncol. 2016 Aug 9. pii: JCO669077.
    PubMed     Text format     Abstract available


    June 2016
  14. FELIX F, Fontenele J
    Valproic Acid May Be Tested in Patients With H3F3A-Mutated High-Grade Gliomas.
    J Clin Oncol. 2016 Jun 13. pii: JCO671073.
    PubMed     Text format    


  15. RUSTHOVEN CG, Doebele RC
    Management of Brain Metastases in ALK-Positive Non-Small-Cell Lung Cancer.
    J Clin Oncol. 2016 Jun 13. pii: JCO672410.
    PubMed     Text format     Abstract available


  16. FAY MF, Head R, Sminia P, Dowson N, et al
    Valproate in Adjuvant Glioblastoma Treatment.
    J Clin Oncol. 2016 Jun 13. pii: JCO672162.
    PubMed     Text format    


    April 2016
  17. CHAMBERLAIN MC
    Targetable Lung Cancer Brain Metastases: Improved Outcome.
    J Clin Oncol. 2016 Apr 25. pii: JCO669465.
    PubMed     Text format    


  18. BRINKMAN TM, Krasin MJ, Liu W, Armstrong GT, et al
    Long-Term Neurocognitive Functioning and Social Attainment in Adult Survivors of Pediatric CNS Tumors: Results From the St Jude Lifetime Cohort Study.
    J Clin Oncol. 2016;34:1358-67.
    PubMed     Text format     Abstract available


  19. FINAZZI T
    One Week of Radiotherapy for Glioblastoma: A Noninferiority Trial?
    J Clin Oncol. 2016 Apr 11. pii: JCO657783.
    PubMed     Text format    


  20. KIM H, Leiby BE, Shi W
    Too Little, Too Soon: Short-Course Radiotherapy in Elderly Patients With Glioblastoma.
    J Clin Oncol. 2016 Apr 11. pii: JCO663195.
    PubMed     Text format    


  21. CHINOT OL, Taphoorn MJ, Bais C, Bourgon R, et al
    Reply to T.J. Kruser et al.
    J Clin Oncol. 2016;34:1282-3.
    PubMed     Text format    


  22. BASS JK, Hua CH, Huang J, Onar-Thomas A, et al
    Hearing Loss in Patients Who Received Cranial Radiation Therapy for Childhood Cancer.
    J Clin Oncol. 2016;34:1248-55.
    PubMed     Text format     Abstract available


  23. LEE EQ, Ruland S, LeBoeuf NR, Wen PY, et al
    Successful Treatment of a Progressive BRAF V600E-Mutated Anaplastic Pleomorphic Xanthoastrocytoma With Vemurafenib Monotherapy.
    J Clin Oncol. 2016;34:e87-9.
    PubMed     Text format    


    March 2016
  24. GILBERT MR
    Antiangiogenic Therapy for Glioblastoma: Complex Biology and Complicated Results.
    J Clin Oncol. 2016 Mar 21. pii: JCO665364.
    PubMed     Text format    


  25. BOUFFET E, Larouche V, Campbell BB, Merico D, et al
    Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency.
    J Clin Oncol. 2016 Mar 21. pii: JCO666552.
    PubMed     Text format     Abstract available


  26. HERRLINGER U, Schafer N, Steinbach JP, Weyerbrock A, et al
    Bevacizumab Plus Irinotecan Versus Temozolomide in Newly Diagnosed O6-Methylguanine-DNA Methyltransferase Nonmethylated Glioblastoma: The Randomized GLARIUS Trial.
    J Clin Oncol. 2016 Mar 14. pii: JCO634691.
    PubMed     Text format     Abstract available


  27. KRUSER TJ
    Systemic Therapy in Unresectable Meningioma Before Radiotherapy.
    J Clin Oncol. 2016 Mar 14. pii: JCO665901.
    PubMed     Text format    


  28. CHAMBERLAIN MC
    What Lessons Are Imparted From SWOG S9005 for Recurrent Meningioma?
    J Clin Oncol. 2016 Mar 14. pii: JCO662288.
    PubMed     Text format    


  29. BAGATELL R, McHugh K, Naranjo A, Van Ryn C, et al
    Assessment of Primary Site Response in Children With High-Risk Neuroblastoma: An International Multicenter Study.
    J Clin Oncol. 2016;34:740-6.
    PubMed     Text format     Abstract available


    February 2016
  30. RADES D, Segedin B, Conde-Moreno AJ, Garcia R, et al
    Radiotherapy With 4 Gy x 5 Versus 3 Gy x 10 for Metastatic Epidural Spinal Cord Compression: Final Results of the SCORE-2 Trial (ARO 2009/01).
    J Clin Oncol. 2016;34:597-602.
    PubMed     Text format     Abstract available


  31. KRUSER TJ, Mehta MP, Kozak KR
    Identification of Patients Who Benefit From Bevacizumab in High-Grade Glioma-An Easy Question Turned Difficult: Treat the Scan or the Patient?
    J Clin Oncol. 2016 Feb 16. pii: JCO647883.
    PubMed     Text format    


  32. PIETANZA MC
    Using a Population-Based Analysis to Determine the Management and Treatment of Early-Stage Small-Cell Lung Cancer.
    J Clin Oncol. 2016 Feb 16. pii: JCO656462.
    PubMed     Text format    


  33. FREEDMAN RA, Gelman RS, Wefel JS, Melisko ME, et al
    Translational Breast Cancer Research Consortium (TBCRC) 022: A Phase II Trial of Neratinib for Patients With Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer and Brain Metastases.
    J Clin Oncol. 2016 Feb 1. pii: JCO630343.
    PubMed     Text format     Abstract available


    January 2016
  34. SANDS SA
    Proton Beam Radiation Therapy: The Future May Prove Brighter for Pediatric Patients With Brain Tumors.
    J Clin Oncol. 2016 Jan 25. pii: JCO654350.
    PubMed     Text format    


  35. KAHALLEY LS, Ris MD, Grosshans DR, Okcu MF, et al
    Comparing Intelligence Quotient Change After Treatment With Proton Versus Photon Radiation Therapy for Pediatric Brain Tumors.
    J Clin Oncol. 2016 Jan 25. pii: JCO621383.
    PubMed     Text format     Abstract available


  36. TAPHOORN MJ
    Reply to M.C. Chamberlain.
    J Clin Oncol. 2016;34:292.
    PubMed     Text format    


  37. BERNSTEIN LJ, Mason WP, Laperriere N, Chung C, et al
    Cognitive rehabilitation for brain tumor survivors: A pilot study.
    J Clin Oncol. 2016;34.
    PubMed     Text format     Abstract available


  38. HAPPOLD C, Gorlia T, Chinot O, Gilbert MR, et al
    Does Valproic Acid or Levetiracetam Improve Survival in Glioblastoma? A Pooled Analysis of Prospective Clinical Trials in Newly Diagnosed Glioblastoma.
    J Clin Oncol. 2016 Jan 19. pii: JCO636563.
    PubMed     Text format     Abstract available


  39. YANG CJ, Chan DY, Speicher PJ, Gulack BC, et al
    Role of Adjuvant Therapy in a Population-Based Cohort of Patients With Early-Stage Small-Cell Lung Cancer.
    J Clin Oncol. 2016 Jan 19. pii: JCO638171.
    PubMed     Text format     Abstract available


    December 2015
  40. GILLIGAN T
    Decision Making in a Data-Poor Environment: Management of Brain Metastases From Testicular and Extragonadal Germ Cell Tumors.
    J Clin Oncol. 2015 Dec 14. pii: JCO640110.
    PubMed     Text format     Abstract available


  41. KLEINBERG LR
    Reply to C.T. Hiley.
    J Clin Oncol. 2015;33:4122-3.
    PubMed     Text format    


    November 2015
  42. CHAMBERLAIN MC
    Similar Trials With Differing Outcomes: Reconciliation in Glioblastoma.
    J Clin Oncol. 2015 Nov 30. pii: JCO641746.
    PubMed     Text format    


  43. SHI W, Dicker AP
    CNS Metastases in Patients With Non-Small-Cell Lung Cancer and ALK Gene Rearrangement.
    J Clin Oncol. 2015 Nov 30. pii: JCO639682.
    PubMed     Text format    


  44. OU SI, Ahn JS, De Petris L, Govindan R, et al
    Alectinib in Crizotinib-Refractory ALK-Rearranged Non-Small-Cell Lung Cancer: A Phase II Global Study.
    J Clin Oncol. 2015 Nov 23. pii: JCO639443.
    PubMed     Text format     Abstract available


  45. EATON RUSSELL CJ, Bouffet E
    Reply to L. Wiener et al.
    J Clin Oncol. 2015;33:3975.
    PubMed     Text format    


  46. WIENER L, Feudtner C, Hinds P, Wolfe J, et al
    Deeper Conversations Need Not Wait Until the End.
    J Clin Oncol. 2015;33:3974.
    PubMed     Text format    


  47. JI Y, Rankin C, Grunberg S, Sherrod AE, et al
    Double-Blind Phase III Randomized Trial of the Antiprogestin Agent Mifepristone in the Treatment of Unresectable Meningioma: SWOG S9005.
    J Clin Oncol. 2015 Nov 2. pii: JCO.2015.61.6490.
    PubMed     Text format     Abstract available


  48. TURCOTTE LM, Whitton JA, Friedman DL, Hammond S, et al
    Risk of Subsequent Neoplasms During the Fifth and Sixth Decades of Life in the Childhood Cancer Survivor Study Cohort.
    J Clin Oncol. 2015;33:3568-75.
    PubMed     Text format     Abstract available


    October 2015
  49. KNISELY JP
    One and Done: A Week of Radiotherapy for Glioblastoma.
    J Clin Oncol. 2015 Oct 26. pii: JCO.2015.64.0763.
    PubMed     Text format    


  50. FELDMAN DR, Lorch A, Kramar A, Albany C, et al
    Brain Metastases in Patients With Germ Cell Tumors: Prognostic Factors and Treatment Options-An Analysis From the Global Germ Cell Cancer Group.
    J Clin Oncol. 2015 Oct 12. pii: JCO.2015.62.7000.
    PubMed     Text format     Abstract available


  51. JOHUNG KL, Yeh N, Desai NB, Williams TM, et al
    Extended Survival and Prognostic Factors for Patients With ALK-Rearranged Non-Small-Cell Lung Cancer and Brain Metastasis.
    J Clin Oncol. 2015 Oct 5. pii: JCO.2015.62.0138.
    PubMed     Text format     Abstract available


  52. GOUNDER MM, Nayak L, Sahebjam S, Muzikansky A, et al
    Evaluation of the Safety and Benefit of Phase I Oncology Trials for Patients With Primary CNS Tumors.
    J Clin Oncol. 2015;33:3186-92.
    PubMed     Text format     Abstract available


    September 2015
  53. ROA W, Kepka L, Kumar N, Sinaika V, et al
    International Atomic Energy Agency Randomized Phase III Study of Radiation Therapy in Elderly and/or Frail Patients With Newly Diagnosed Glioblastoma Multiforme.
    J Clin Oncol. 2015 Sep 21. pii: JCO.2015.62.6606.
    PubMed     Text format     Abstract available


  54. HILEY CT
    Cognitive Impairment in Survivors of Irradiated Brain Tumors Is Multifactorial: Implications of Polypharmacy With Antiepileptics?
    J Clin Oncol. 2015 Sep 14. pii: JCO.2015.62.5350.
    PubMed     Text format    


    August 2015
  55. GAJJAR A, Bowers DC, Karajannis MA, Leary S, et al
    Pediatric Brain Tumors: Innovative Genomic Information Is Transforming the Diagnostic and Clinical Landscape.
    J Clin Oncol. 2015 Aug 24. pii: JCO.2014.59.9217.
    PubMed     Text format     Abstract available


  56. LIN X, DeAngelis LM
    Treatment of Brain Metastases.
    J Clin Oncol. 2015 Aug 17. pii: JCO.2015.60.9503.
    PubMed     Text format     Abstract available


  57. SCHMITZ N, Wu HS
    Advances in the Treatment of Secondary CNS Lymphoma.
    J Clin Oncol. 2015 Aug 17. pii: JCO.2015.63.1143.
    PubMed     Text format    


  58. FERRERI AJ, Donadoni G, Cabras MG, Patti C, et al
    High Doses of Antimetabolites Followed by High-Dose Sequential Chemoimmunotherapy and Autologous Stem-Cell Transplantation in Patients With Systemic B-Cell Lymphoma and Secondary CNS Involvement: Final Results of a Multicenter Phase II Trial.
    J Clin Oncol. 2015 Aug 17. pii: JCO.2015.61.1236.
    PubMed     Text format     Abstract available


  59. GOLDMAN S, Bouffet E, Fisher PG, Allen JC, et al
    Phase II Trial Assessing the Ability of Neoadjuvant Chemotherapy With or Without Second-Look Surgery to Eliminate Measurable Disease for Nongerminomatous Germ Cell Tumors: A Children's Oncology Group Study.
    J Clin Oncol. 2015;33:2464-71.
    PubMed     Text format     Abstract available


    July 2015
  60. RANSOHOFF KJ, Sarin KY, Tang JY
    Smoothened Inhibitors in Sonic Hedgehog Subgroup Medulloblastoma.
    J Clin Oncol. 2015 Jul 20. pii: JCO.2015.62.2225.
    PubMed     Text format    


  61. MAYER TM
    Can We Predict Bevacizumab Responders in Patients With Glioblastoma?
    J Clin Oncol. 2015 Jul 20. pii: JCO.2015.62.3637.
    PubMed     Text format    


  62. MORK ME, You YN, Ying J, Bannon SA, et al
    High Prevalence of Hereditary Cancer Syndromes in Adolescents and Young Adults With Colorectal Cancer.
    J Clin Oncol. 2015 Jul 20. pii: JCO.2015.61.4503.
    PubMed     Text format     Abstract available


  63. ROBINSON GW, Orr BA, Wu G, Gururangan S, et al
    Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032.
    J Clin Oncol. 2015 Jul 13. pii: JCO.2014.60.1591.
    PubMed     Text format     Abstract available


    June 2015
  64. SANDMANN T, Bourgon R, Garcia J, Li C, et al
    Patients With Proneural Glioblastoma May Derive Overall Survival Benefit From the Addition of Bevacizumab to First-Line Radiotherapy and Temozolomide: Retrospective Analysis of the AVAglio Trial.
    J Clin Oncol. 2015 Jun 29. pii: JCO.2015.61.5005.
    PubMed     Text format     Abstract available


  65. KOTECHA R, Suh JH
    Reply to M.C. Chamberlain.
    J Clin Oncol. 2015;33:1986-7.
    PubMed     Text format    


  66. GONDI V, Tome WA, Mehta MP
    Reply to M.C. Chamberlain.
    J Clin Oncol. 2015;33:1986.
    PubMed     Text format    


  67. WOLFE J, Orellana L, Ullrich C, Cook EF, et al
    Symptoms and Distress in Children With Advanced Cancer: Prospective Patient-Reported Outcomes From the PediQUEST Study.
    J Clin Oncol. 2015;33:1928-35.
    PubMed     Text format     Abstract available


    May 2015
  68. TAPHOORN MJ, Henriksson R, Bottomley A, Cloughesy T, et al
    Health-Related Quality of Life in a Randomized Phase III Study of Bevacizumab, Temozolomide, and Radiotherapy in Newly Diagnosed Glioblastoma.
    J Clin Oncol. 2015 May 26. pii: JCO.2014.60.3217.
    PubMed     Text format     Abstract available


  69. KOVIC B, Xie F
    Economic Evaluation of Bevacizumab for the First-Line Treatment of Newly Diagnosed Glioblastoma Multiforme.
    J Clin Oncol. 2015 May 26. pii: JCO.2014.59.7245.
    PubMed     Text format     Abstract available


  70. SUBBIAH IM, Lei X, Weinberg JS, Sulman EP, et al
    Validation and Development of a Modified Breast Graded Prognostic Assessment As a Tool for Survival in Patients With Breast Cancer and Brain Metastases.
    J Clin Oncol. 2015 May 18. pii: JCO.2014.58.8517.
    PubMed     Text format     Abstract available


  71. GIBNEY GT, Atkins MB
    Swinging for the Fences: Long-Term Survival With Ipilimumab in Metastatic Melanoma.
    J Clin Oncol. 2015 May 11. pii: JCO.2014.60.1807.
    PubMed     Text format    


    April 2015
  72. RUSSELL CE, Bouffet E
    Profound answers to simple questions.
    J Clin Oncol. 2015;33:1294-6.
    PubMed     Text format    


    October 2014
  73. SMYTH MJ, Yagita H, McArthur GA
    Combination Anti-CTLA-4 and Anti-RANKL in Metastatic Melanoma.
    J Clin Oncol. 2014 Oct 13. pii: JCO.2013.51.3572.
    PubMed     Text format    


    September 2014
  74. ROZATI S, Kempf W, Ostheeren-Michaelis S, Bode-Lesniewska B, et al
    Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type, With Bilateral Intraocular Involvement and Infiltration to the CNS.
    J Clin Oncol. 2014 Sep 29. pii: JCO.2013.51.6559.
    PubMed     Text format    


    April 2014
  75. VAN DEN BROM RR, Makelburg AB, Schroder CP, de Vries EG, et al
    Vemurafenib-Induced Disseminated Intravascular Coagulation in Metastatic Melanoma.
    J Clin Oncol. 2014.
    PubMed     Text format    


  76. WILGENHOF S, Neyns B
    Complete Cytologic Remission of V600E BRAF-Mutant Melanoma-Associated Leptomeningeal Carcinomatosis Upon Treatment With Dabrafenib.
    J Clin Oncol. 2014.
    PubMed     Text format    


    March 2014
  77. SAKURAI H, Sugimoto KJ, Shimada A, Imai H, et al
    Primary CNS CCND1/MYC-Positive Double-Hit B-Cell Lymphoma: A Case Report and Review of the Literature.
    J Clin Oncol. 2014.
    PubMed     Text format    


  78. HSIEH YY, Yang ST, Li WH, Hu CJ, et al
    Primary Leptomeningeal Melanoma Mimicking Meningitis: A Case Report and Literature Review.
    J Clin Oncol. 2014.
    PubMed     Text format    


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