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The Medical Article of the Year 2008: Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78. Free full-text |
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| Colorectal Neoplasms |
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2 Ann Oncol |
Retrieve available abstracts of this week’s articles:
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| Single Articles |
What is the role and impact of molecular markers on treatment decisions in the adjuvant setting of colorectal cancer?
Ann Oncol. 2008;19 Suppl 7:vii184-6.
PubMed
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Challenges in treating older cancer patients: colon cancer.
Ann Oncol. 2008;19 Suppl 7:vii104-8.
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SPMSP: a solid-phase PCR with colorimetric read-out for quantitative methylation analysis.
Anticancer Res. 2008;28.
PubMed
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Long-term postoperative adjuvant chemotherapy of UFT/LV improves survival in a primary tumor resection-pulmonary metastasis model.
Anticancer Res. 2008;28.
PubMed
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The impact of old age on cancer-specific and non-cancer-related survival following elective potentially curative surgery for Dukes A/B colorectal cancer.
Br J Cancer. 2008.
PubMed
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Pharmacogenetic prediction of clinical outcome in advanced colorectal cancer patients receiving oxaliplatin/5-fluorouracil as first-line chemotherapy.
Br J Cancer. 2008.
PubMed
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Pharmacokinetic and pharmacogenetic determinants of the activity and toxicity of irinotecan in metastatic colorectal cancer patients.
Br J Cancer. 2008.
PubMed
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GSTP1 Ile105Val polymorphism correlates with progression-free survival in MCRC patients treated with or without irinotecan: a study of the Dutch Colorectal Cancer Group.
Br J Cancer. 2008.
PubMed
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Abstract available
In vitro and in vivo anticancer efficacy of unconjugated humanized anti-CEA monoclonal antibodies.
Br J Cancer. 2008;99:837-8.
PubMed
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Poorer outcome in stromal HIF-2 alpha- and CA9-positive colorectal adenocarcinomas is associated with wild-type TP53 but not with BNIP3 promoter hypermethylation or apoptosis.
Br J Cancer. 2008;99:727-33.
PubMed
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Fractionated 131I anti-CEA radioimmunotherapy: effects on xenograft tumour growth and haematological toxicity in mice.
Br J Cancer. 2008;99:632-8.
PubMed
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Abstract available
Detection of circulating tumour cells in peripheral blood with an automated scanning fluorescence microscope.
Br J Cancer. 2008;99:789-95.
PubMed
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Limits of observational data in determining outcomes from cancer therapy.
Cancer. 2008;112:2456-66.
PubMed
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Maslinic acid, a natural triterpene from Olea europaea L., induces apoptosis in HT29 human colon-cancer cells via the mitochondrial apoptotic pathway.
Cancer Lett. 2008.
PubMed
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Abstract available
Curcumin inhibits the proteasome activity in human colon cancer cells in vitro and in vivo.
Cancer Res. 2008;68:7283-92.
PubMed
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Abstract available
Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines.
Cancer Res. 2008;68:7258-63.
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Molecular basis for the induction of an angiogenesis inhibitor, thrombospondin-1, by 5-fluorouracil.
Cancer Res. 2008;68:7035-41.
PubMed
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Abstract available
Clinical usefulness of EGFR gene copy number as a predictive marker in colorectal cancer patients treated with cetuximab: a fluorescent in situ hybridization study.
Clin Cancer Res. 2008;14:5869-76.
PubMed
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Control of cell growth and survival by enzymes of the fatty acid synthesis pathway in HCT-116 colon cancer cells.
Clin Cancer Res. 2008;14:5735-42.
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Light delivery over extended time periods enhances the effectiveness of photodynamic therapy.
Clin Cancer Res. 2008;14:2796-805.
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Epigenetic-genetic interactions in the APC/WNT, RAS/RAF, and P53 pathways in colorectal carcinoma.
Clin Cancer Res. 2008;14:2560-9.
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Proximal and distal colorectal cancers show distinct gene-specific methylation profiles and clinical and molecular characteristics.
Eur J Cancer. 2008;44:1290-301.
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Identification of new accessible tumor antigens in human colon cancer by ex vivo protein biotinylation and comparative mass spectrometry analysis.
Int J Cancer. 2008.
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Review: Biological relevance of disseminated tumor cells in cancer patients.
Int J Cancer. 2008;123:1991-2006.
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Angiostatic immune reaction in colorectal carcinoma: Impact on survival and perspectives for antiangiogenic therapy.
Int J Cancer. 2008;123:2120-9.
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Double primary malignancy in colorectal cancer patients-MSI is the useful marker for predicting double primary tumors.
Int J Colorectal Dis. 2008.
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Multiple primary cancers in extracolonic sites with colorectal cancer.
Int J Colorectal Dis. 2008.
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Patient Age and Comorbidity Are Major Determinants of Adjuvant Chemotherapy Use for Stage III Colon Cancer in Routine Clinical Practice.
J Clin Oncol. 2008;26:4516-7.
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Prospective relationships of physical activity with quality of life among colorectal cancer survivors.
J Clin Oncol. 2008;26:4480-7.
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Abstract available
Adjuvant Chemotherapy After Potentially Curative Resection of Metastases From Colorectal Cancer: A Pooled Analysis of Two Randomized Trials.
J Clin Oncol. 2008.
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Abstract available
StatBite: Cancer incidence among HIV-infected individuals in the U.S., 2000-2003.
J Natl Cancer Inst. 2008;100:1199.
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A modern regimen of pre-operative concurrent chemo-radiation therapy in locally advanced rectal cancer.
J Surg Oncol. 2008;98:167-74.
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Abstract available
The impact of T and N stage on long-term survival of rectal cancer patients in the community.
J Surg Oncol. 2008;98:161-6.
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Small-bowel cancer in Lynch syndrome: is it time for surveillance?
Lancet Oncol. 2008;9:901-5.
PubMed
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Colorectal cancer screening on stronger footing.
N Engl J Med. 2008;359:1285-7.
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