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  Colorectal Neoplasms

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Articles published in Oncogene

Retrieve available abstracts of 60 articles:
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Single Articles


    January 2018
  1. SHEN L, Qu X, Li H, Xu C, et al
    NDRG2 facilitates colorectal cancer differentiation through the regulation of Skp2-p21/p27 axis.
    Oncogene. 2018 Jan 18. pii: 10.1038/s41388-017-0118.
    PubMed     Text format     Abstract available


  2. SOLOMON H, Dinowitz N, Pateras IS, Cooks T, et al
    Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers.
    Oncogene. 2018 Jan 18. pii: 10.1038/s41388-017-0060.
    PubMed     Text format     Abstract available


  3. HERR R, Halbach S, Heizmann M, Busch H, et al
    BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines.
    Oncogene. 2018 Jan 12. pii: 10.1038/s41388-017-0063.
    PubMed     Text format     Abstract available


    December 2017
  4. OMOTO T, Kim-Kaneyama JR, Lei XF, Orimo A, et al
    The impact of stromal Hic-5 on the tumorigenesis of colorectal cancer through lysyl oxidase induction and stromal remodeling.
    Oncogene. 2017 Dec 15. pii: 10.1038/s41388-017-0033.
    PubMed     Text format     Abstract available


  5. BLOMME A, Van Simaeys G, Doumont G, Costanza B, et al
    Murine stroma adopts a human-like metabolic phenotype in the PDX model of colorectal cancer and liver metastases.
    Oncogene. 2017 Dec 15. pii: 10.1038/s41388-017-0018.
    PubMed     Text format     Abstract available


  6. LEE SH, Yu J, Hwang GH, Kim S, et al
    CUT-PCR: CRISPR-mediated, ultrasensitive detection of target DNA using PCR.
    Oncogene. 2017;36:6823-6829.
    PubMed     Text format     Abstract available


    November 2017
  7. HATA AN, Rowley S, Archibald HL, Gomez-Caraballo M, et al
    Synergistic activity and heterogeneous acquired resistance of combined MDM2 and MEK inhibition in KRAS mutant cancers.
    Oncogene. 2017;36:6581-6591.
    PubMed     Text format     Abstract available


  8. LEE JH, Han YS, Yoon YM, Yun CW, et al
    Role of HSPA1L as a cellular prion protein stabilizer in tumor progression via HIF-1alpha/GP78 axis.
    Oncogene. 2017;36:6555-6567.
    PubMed     Text format     Abstract available


  9. WANG Q, Zhu J, Wang YW, Dai Y, et al
    Tumor suppressor Pdcd4 attenuates Sin1 translation to inhibit invasion in colon carcinoma.
    Oncogene. 2017;36:6225-6234.
    PubMed     Text format     Abstract available


  10. TRINIDAD AG, Whalley N, Rowlinson R, Delpuech O, et al
    Pyruvate dehydrogenase kinase 4 exhibits a novel role in the activation of mutant KRAS, regulating cell growth in lung and colorectal tumour cells.
    Oncogene. 2017;36:6164-6176.
    PubMed     Text format     Abstract available


    October 2017
  11. SCHROYER AL, Stimes NW, Abi Saab WF, Chadee DN, et al
    MLK3 phosphorylation by ERK1/2 is required for oxidative stress-induced invasion of colorectal cancer cells.
    Oncogene. 2017 Oct 30. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


  12. BENTHANI FA, Herrmann D, Tran PN, Pangon L, et al
    'MCC' protein interacts with E-cadherin and beta-catenin strengthening cell-cell adhesion of HCT116 colon cancer cells.
    Oncogene. 2017 Oct 16. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


  13. WEISENBERGER DJ, Liang G, Lenz HJ
    DNA methylation aberrancies delineate clinically distinct subsets of colorectal cancer and provide novel targets for epigenetic therapies.
    Oncogene. 2017 Oct 9. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


  14. WANG LF, Liu YS, Yang B, Li P, et al
    The extracellular matrix protein mindin attenuates colon cancer progression by blocking angiogenesis via Egr-1-mediated regulation.
    Oncogene. 2017 Oct 9. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


    September 2017
  15. FU LN, Wang YQ, Tan J, Xu J, et al
    Role of JMJD2B in colon cancer cell survival under glucose-deprived conditions and the underlying mechanisms.
    Oncogene. 2017 Sep 25. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


  16. LIU L, Wong CC, Gong B, Yu J, et al
    Functional significance and therapeutic implication of ring-type E3 ligases in colorectal cancer.
    Oncogene. 2017 Sep 18. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


    August 2017
  17. WANG X, Haring MF, Rathjen T, Lockhart SM, et al
    Insulin resistance in vascular endothelial cells promotes intestinal tumour formation.
    Oncogene. 2017;36:4987-4996.
    PubMed     Text format     Abstract available


  18. HANLEY MP, Hahn MA, Li AX, Wu X, et al
    Genome-wide DNA methylation profiling reveals cancer-associated changes within early colonic neoplasia.
    Oncogene. 2017;36:5035-5044.
    PubMed     Text format     Abstract available


  19. DIEHL K, Dinges LA, Helm O, Ammar N, et al
    Nuclear factor E2-related factor-2 has a differential impact on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells: a condition favoring metabolic symbiosis between colorectal cancer and stromal cells.
    Oncogene. 2017 Aug 28. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


  20. WANG G, Fu Y, Yang X, Luo X, et al
    Brg-1 targeting of novel miR550a-5p/RNF43/Wnt signaling axis regulates colorectal cancer metastasis.
    Oncogene. 2017 Aug 28. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


  21. RUAN H, Zhan YY, Hou J, Xu B, et al
    Berberine binds RXRalpha to suppress beta-catenin signaling in colon cancer cells.
    Oncogene. 2017 Aug 28. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


  22. LI XX, Zhang HS, Xu YM, Zhang RJ, et al
    Knockdown of IRE1alpha inhibits colonic tumorigenesis through decreasing beta-catenin and IRE1alpha targeting suppresses colon cancer cells.
    Oncogene. 2017 Aug 21. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


  23. SUMNER ET, Chawla AT, Cororaton AD, Koblinski JE, et al
    Transforming activity and therapeutic targeting of C-terminal-binding protein 2 in Apc-mutated neoplasia.
    Oncogene. 2017;36:4810-4816.
    PubMed     Text format     Abstract available


  24. AHMAD R, Kumar B, Chen Z, Chen X, et al
    Loss of claudin-3 expression induces IL6/gp130/Stat3 signaling to promote colon cancer malignancy by hyperactivating Wnt/beta-catenin signaling.
    Oncogene. 2017 Aug 7. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


    July 2017
  25. YE J, Wei X, Shang Y, Pan Q, et al
    Core 3 mucin-type O-glycan restoration in colorectal cancer cells promotes MUC1/p53/miR-200c-dependent epithelial identity.
    Oncogene. 2017 Jul 24. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


  26. MA X, Meng Z, Jin L, Xiao Z, et al
    CAMK2gamma in intestinal epithelial cells modulates colitis-associated colorectal carcinogenesis via enhancing STAT3 activation.
    Oncogene. 2017;36:4060-4071.
    PubMed     Text format     Abstract available


  27. TSOI H, Lam KC, Dong Y, Zhang X, et al
    Pre-45s rRNA promotes colon cancer and is associated with poor survival of CRC patients.
    Oncogene. 2017 Jul 10. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


  28. JU HQ, Lu YX, Wu QN, Liu J, et al
    Disrupting G6PD-mediated Redox homeostasis enhances chemosensitivity in colorectal cancer.
    Oncogene. 2017 Jul 10. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


  29. HARDBOWER DM, Coburn LA, Asim M, Singh K, et al
    EGFR-mediated macrophage activation promotes colitis-associated tumorigenesis.
    Oncogene. 2017;36:3807-3819.
    PubMed     Text format     Abstract available


    June 2017
  30. LI Y, Zhou T, Wang Y, Ning C, et al
    The protumorigenic potential of FTY720 by promoting extramedullary hematopoiesis and MDSC accumulation.
    Oncogene. 2017;36:3760-3771.
    PubMed     Text format     Abstract available


  31. ROS S, Floter J, Kaymak I, Da Costa C, et al
    6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells.
    Oncogene. 2017;36:3287-3299.
    PubMed     Text format     Abstract available


    May 2017
  32. KRAMER N, Schmollerl J, Unger C, Nivarthi H, et al
    Autocrine WNT2 signaling in fibroblasts promotes colorectal cancer progression.
    Oncogene. 2017 May 29. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


  33. UNGER C, Kramer N, Unterleuthner D, Scherzer M, et al
    Stromal-derived IGF2 promotes colon cancer progression via paracrine and autocrine mechanisms.
    Oncogene. 2017 May 22. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


  34. PEK M, Yatim SMJM, Chen Y, Li J, et al
    Oncogenic KRAS-associated gene signature defines co-targeting of CDK4/6 and MEK as a viable therapeutic strategy in colorectal cancer.
    Oncogene. 2017 May 1. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


    April 2017
  35. MERTZ TM, Baranovskiy AG, Wang J, Tahirov TH, et al
    Nucleotide selectivity defect and mutator phenotype conferred by a colon cancer-associated DNA polymerase delta mutation in human cells.
    Oncogene. 2017 Apr 3. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


    March 2017
  36. MI L, Zhu F, Yang X, Lu J, et al
    The metastatic suppressor NDRG1 inhibits EMT, migration and invasion through interaction and promotion of caveolin-1 ubiquitylation in human colorectal cancer cells.
    Oncogene. 2017 Mar 27. doi: 10.1038/onc.2017.
    PubMed     Text format     Abstract available


  37. ZHANG Q, Wei T, Shim K, Wright K, et al
    Atypical role of sprouty in colorectal cancer: sprouty repression inhibits epithelial-mesenchymal transition.
    Oncogene. 2017 Mar 13. doi: 10.1038/onc.2017.
    PubMed     Text format    


    January 2017
  38. YI H, Geng L, Black A, Talmon G, et al
    The miR-487b-3p/GRM3/TGFbeta signaling axis is an important regulator of colon cancer tumorigenesis.
    Oncogene. 2017 Jan 23. doi: 10.1038/onc.2016.
    PubMed     Text format     Abstract available


  39. GUEGUINOU M, Crottes D, Chantome A, Rapetti-Mauss R, et al
    The SigmaR1 chaperone drives breast and colorectal cancer cell migration by tuning SK3-dependent Ca2+ homeostasis.
    Oncogene. 2017 Jan 23. doi: 10.1038/onc.2016.
    PubMed     Text format     Abstract available


  40. AGARWAL E, Robb CM, Smith LM, Brattain MG, et al
    Role of Akt2 in regulation of metastasis suppressor 1 expression and colorectal cancer metastasis.
    Oncogene. 2017 Jan 9. doi: 10.1038/onc.2016.
    PubMed     Text format     Abstract available


    December 2016
  41. WANG T, Xu X, Xu Q, Ren J, et al
    miR-19a promotes colitis-associated colorectal cancer by regulating tumor necrosis factor alpha-induced protein 3-NF-kappaB feedback loops.
    Oncogene. 2016 Dec 19. doi: 10.1038/onc.2016.
    PubMed     Text format     Abstract available


    November 2016
  42. JIA H, Song L, Cong Q, Wang J, et al
    The LIM protein AJUBA promotes colorectal cancer cell survival through suppression of JAK1/STAT1/IFIT2 network.
    Oncogene. 2016 Nov 28. doi: 10.1038/onc.2016.
    PubMed     Text format     Abstract available


  43. BERTHENET K, Bokhari A, Lagrange A, Marcion G, et al
    HSP110 promotes colorectal cancer growth through STAT3 activation.
    Oncogene. 2016 Nov 7. doi: 10.1038/onc.2016.
    PubMed     Text format     Abstract available


    October 2016
  44. MATSUMURA K, Kawasaki Y, Miyamoto M, Kamoshida Y, et al
    The novel G-quadruplex-containing long non-coding RNA GSEC antagonizes DHX36 and modulates colon cancer cell migration.
    Oncogene. 2016 Oct 31. doi: 10.1038/onc.2016.
    PubMed     Text format     Abstract available


    September 2016
  45. CHANDRASINGHE P, Stebbing J, Warusavitarne J
    The MACC1-SPON2 axis: A new biomarker and therapeutic target in colorectal cancer.
    Oncogene. 2016 Sep 26. doi: 10.1038/onc.2016.
    PubMed     Text format     Abstract available


  46. HAASE G, Gavert N, Brabletz T, Ben-Ze'ev A, et al
    A point mutation in the extracellular domain of L1 blocks its capacity to confer metastasis in colon cancer cells via CD10.
    Oncogene. 2016 Sep 19. doi: 10.1038/onc.2016.
    PubMed     Text format     Abstract available


  47. LIU CC, Cai DL, Sun F, Wu ZH, et al
    FERMT1 mediates epithelial-mesenchymal transition to promote colon cancer metastasis via modulation of beta-catenin transcriptional activity.
    Oncogene. 2016 Sep 19. doi: 10.1038/onc.2016.
    PubMed     Text format     Abstract available


  48. WANG J, Zhang B, Wu H, Cai J, et al
    CD51 correlates with the TGF-beta pathway and is a functional marker for colorectal cancer stem cells.
    Oncogene. 2016 Sep 5. doi: 10.1038/onc.2016.
    PubMed     Text format     Abstract available


    July 2016
  49. SHENG YH, He Y, Hasnain SZ, Wang R, et al
    MUC13 protects colorectal cancer cells from death by activating the NF-kappaB pathway and is a potential therapeutic target.
    Oncogene. 2016 Jul 11. doi: 10.1038/onc.2016.
    PubMed     Text format     Abstract available


  50. TONG J, Tan S, Zou F, Yu J, et al
    FBW7 mutations mediate resistance of colorectal cancer to targeted therapies by blocking Mcl-1 degradation.
    Oncogene. 2016 Jul 11. doi: 10.1038/onc.2016.
    PubMed     Text format     Abstract available


  51. ZHANG X, Zhang L, Du Y, Zheng H, et al
    A novel FOXM1 isoform, FOXM1D, promotes epithelial-mesenchymal transition and metastasis through ROCKs activation in colorectal cancer.
    Oncogene. 2016 Jul 11. doi: 10.1038/onc.2016.
    PubMed     Text format     Abstract available


  52. ZHONG H, Fazenbaker C, Chen C, Breen S, et al
    Overproduction of IGF-2 drives a subset of colorectal cancer cells, which specifically respond to an anti-IGF therapeutic antibody and combination therapies.
    Oncogene. 2016 Jul 11. doi: 10.1038/onc.2016.
    PubMed     Text format     Abstract available


  53. ZHANG Z, Liu X, Feng B, Liu N, et al
    STIM1, a direct target of microRNA-185, promotes tumor metastasis and is associated with poor prognosis in colorectal cancer.
    Oncogene. 2016 Jul 4. doi: 10.1038/onc.2016.
    PubMed     Text format    


    June 2016
  54. PARANG B, Bradley AM, Mittal MK, Short SP, et al
    Myeloid translocation genes differentially regulate colorectal cancer programs.
    Oncogene. 2016 Jun 6. doi: 10.1038/onc.2016.
    PubMed     Text format     Abstract available


  55. QU X, Sandmann T, Frierson H Jr, Fu L, et al
    Integrated genomic analysis of colorectal cancer progression reveals activation of EGFR through demethylation of the EREG promoter.
    Oncogene. 2016 Jun 6. doi: 10.1038/onc.2016.
    PubMed     Text format     Abstract available


    May 2016
  56. FESSLER E, Jansen M, De Sousa E Melo F, Zhao L, et al
    A multidimensional network approach reveals microRNAs as determinants of the mesenchymal colorectal cancer subtype.
    Oncogene. 2016 May 9. doi: 10.1038/onc.2016.
    PubMed     Text format     Abstract available


    February 2016
  57. YIN N, Qi X, Tsai S, Lu Y, et al
    p38gamma MAPK is required for inflammation-associated colon tumorigenesis.
    Oncogene. 2016;35:1039-48.
    PubMed     Text format     Abstract available


    January 2016
  58. ONEYAMA C, Yoshikawa Y, Ninomiya Y, Iino T, et al
    Fer tyrosine kinase oligomer mediates and amplifies Src-induced tumor progression.
    Oncogene. 2016;35:501-12.
    PubMed     Text format     Abstract available


  59. TENG Y, Ren X, Li H, Shull A, et al
    Mitochondrial ATAD3A combines with GRP78 to regulate the WASF3 metastasis-promoting protein.
    Oncogene. 2016;35:333-43.
    PubMed     Text format     Abstract available


  60. PNG CW, Weerasooriya M, Guo J, James SJ, et al
    DUSP10 regulates intestinal epithelial cell growth and colorectal tumorigenesis.
    Oncogene. 2016;35:206-17.
    PubMed     Text format     Abstract available


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