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The Medical Article of the Year 2008:
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78.
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  Colorectal Neoplasms

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Articles published in Oncogene

Retrieve available abstracts of 50 articles:
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Single Articles


    June 2008
  1. FUKUYAMA R , Niculaita R, Ng KP, Obusez E, et al
    Mutated in colorectal cancer, a putative tumor suppressor for serrated colorectal cancer, selectively represses beta-catenin-dependent transcription.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


  2. SHAHRZAD S , Shirasawa S, Sasazuki T, Rak JW, et al
    Low-dose metronomic cyclophosphamide treatment mediates ischemia-dependent K-ras mutation in colorectal carcinoma xenografts.
    Oncogene. 2008;27:3729-38.
    PubMed     Related articles    Abstract available


  3. KIM MS , Chang X, Yamashita K, Nagpal JK, et al
    Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma.
    Oncogene. 2008;27:3624-34.
    PubMed     Related articles    Abstract available


  4. CASPI M , Zilberberg A, Eldar-Finkelman H, Rosin-Arbesfeld R, et al
    Nuclear GSK-3beta inhibits the canonical Wnt signalling pathway in a beta-catenin phosphorylation-independent manner.
    Oncogene. 2008;27:3546-55.
    PubMed     Related articles    Abstract available


  5. ABUBAKER J , Bavi P, Al-Harbi S, Ibrahim M, et al
    Clinicopathological analysis of colorectal cancers with PIK3CA mutations in Middle Eastern population.
    Oncogene. 2008;27:3539-45.
    PubMed     Related articles    Abstract available


    May 2008
  6. GODA AE , Yoshida T, Horinaka M, Yasuda T, et al
    Mechanisms of enhancement of TRAIL tumoricidal activity against human cancer cells of different origin by dipyridamole.
    Oncogene. 2008;27:3435-45.
    PubMed     Related articles    Abstract available


    April 2008
  7. LOVERIDGE CJ , MacDonald AD, Thoms HC, Dunlop MG, et al
    The proapoptotic effects of sulindac, sulindac sulfone and indomethacin are mediated by nucleolar translocation of the RelA(p65) subunit of NF-kappaB.
    Oncogene. 2008;27:2648-55.
    PubMed     Related articles    Abstract available


  8. PENDAS-FRANCO N , Garcia JM, Pena C, Valle N, et al
    DICKKOPF-4 is induced by TCF/beta-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1alpha,25-dihydroxyvitamin D(3).
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


  9. RAO PR , Makhijani K, Shashidhara LS
    Human APC sequesters beta-catenin even in the absence of GSK-3beta in a Drosophila model.
    Oncogene. 2008;27:2488-93.
    PubMed     Related articles    Abstract available


    March 2008
  10. KIM MS , Chang X, Nagpal JK, Yamashita K, et al
    The N-methyl-D-aspartate receptor type 2A is frequently methylated in human colorectal carcinoma and suppresses cell growth.
    Oncogene. 2008;27:2045-54.
    PubMed     Related articles    Abstract available


  11. TOSCANO F , Fajoui ZE, Gay F, Lalaoui N, et al
    p53-Mediated upregulation of DcR1 impairs oxaliplatin/TRAIL-induced synergistic anti-tumour potential in colon cancer cells.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


  12. KIDOKORO T , Tanikawa C, Furukawa Y, Katagiri T, et al
    CDC20, a potential cancer therapeutic target, is negatively regulated by p53.
    Oncogene. 2008;27:1562-71.
    PubMed     Related articles    Abstract available


  13. WANG Q , Sun Z, Yang HS
    Downregulation of tumor suppressor Pdcd4 promotes invasion and activates both beta-catenin/Tcf and AP-1-dependent transcription in colon carcinoma cells.
    Oncogene. 2008;27:1527-35.
    PubMed     Related articles    Abstract available


  14. GOUYER V , Fontaine D, Dumont P, de Wever O, et al
    Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


    February 2008
  15. GRADY WM , Parkin RK, Mitchell PS, Lee JH, et al
    Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


  16. KWONG LN , Weiss KR, Haigis KM, Dove WF, et al
    Atm is a negative regulator of intestinal neoplasia.
    Oncogene. 2008;27:1013-8.
    PubMed     Related articles    Abstract available   Free Full Text


  17. BROOKES MJ , Boult J, Roberts K, Cooper BT, et al
    A role for iron in Wnt signalling.
    Oncogene. 2008;27:966-75.
    PubMed     Related articles    Abstract available


    January 2008
  18. SHEEHAN KM , Gulmann C, Eichler GS, Weinstein JN, et al
    Signal pathway profiling of epithelial and stromal compartments of colonic carcinoma reveals epithelial-mesenchymal transition.
    Oncogene. 2008;27:323-31.
    PubMed     Related articles    Abstract available


    December 2007
  19. KAWASAKI Y , Sagara M, Shibata Y, Shirouzu M, et al
    Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42.
    Oncogene. 2007;26:7620-267.
    PubMed     Related articles    Abstract available


    November 2007
  20. JUNG HJ , Kim EH, Mun JY, Park S, et al
    Base excision DNA repair defect in Gadd45a-deficient cells.
    Oncogene. 2007;26:7517-25.
    PubMed     Related articles    Abstract available


  21. CAPEL E , Flejou JF, Hamelin R
    Assessment of MLH1 promoter methylation in relation to gene expression requires specific analysis.
    Oncogene. 2007;26:7596-600.
    PubMed     Related articles    Abstract available


  22. YANG HY , Wen YY, Lin YI, Pham L, et al
    Roles for negative cell regulator 14-3-3sigma in control of MDM2 activities.
    Oncogene. 2007;26:7355-62.
    PubMed     Related articles    Abstract available


    October 2007
  23. ASANGANI IA , Rasheed SA, Nikolova DA, Leupold JH, et al
    MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  24. AIGNER K , Dampier B, Descovich L, Mikula M, et al
    The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity.
    Oncogene. 2007;26:6979-88.
    PubMed     Related articles    Abstract available


  25. FLINTERMAN MB , Mymryk JS, Klanrit P, Yousef AF, et al
    p400 function is required for the adenovirus E1A-mediated suppression of EGFR and tumour cell killing.
    Oncogene. 2007;26:6863-74.
    PubMed     Related articles    Abstract available


  26. BROUDE EV , Swift ME, Vivo C, Chang BD, et al
    p21(Waf1/Cip1/Sdi1) mediates retinoblastoma protein degradation.
    Oncogene. 2007;26:6954-8.
    PubMed     Related articles    Abstract available


  27. ZHU S , Bjorge JD, Cheng HC, Fujita DJ, et al
    Decreased CHK protein levels are associated with Src activation in colon cancer cells.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


    September 2007
  28. LI Q , Dashwood WM, Zhong X, Nakagama H, et al
    Bcl-2 overexpression in PhIP-induced colon tumors: cloning of the rat Bcl-2 promoter and characterization of a pathway involving beta-catenin, c-Myc and E2F1.
    Oncogene. 2007;26:6194-202.
    PubMed     Related articles    Abstract available


    August 2007
  29. MIQUEL C , Jacob S, Grandjouan S, Aime A, et al
    Frequent alteration of DNA damage signalling and repair pathways in human colorectal cancers with microsatellite instability.
    Oncogene. 2007;26:5919-26.
    PubMed     Related articles    Abstract available


  30. SEBENS MUERKOSTER S , Rausch AV, Isberner A, Minkenberg J, et al
    The apoptosis-inducing effect of gastrin on colorectal cancer cells relates to an increased IEX-1 expression mediating NF-kappaB inhibition.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


    July 2007
  31. MOHR A , Buneker C, Gough RP, Zwacka RM, et al
    MnSOD protects colorectal cancer cells from TRAIL-induced apoptosis by inhibition of Smac/DIABLO release.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  32. RIGBY RJ , Simmons JG, Greenhalgh CJ, Alexander WS, et al
    Suppressor of cytokine signaling 3 (SOCS3) limits damage-induced crypt hyper-proliferation and inflammation-associated tumorigenesis in the colon.
    Oncogene. 2007;26:4833-41.
    PubMed     Related articles    Abstract available


  33. CHUN SY , Chen F, Washburn JG, MacDonald JW, et al
    CDX2 promotes anchorage-independent growth by transcriptional repression of IGFBP-3.
    Oncogene. 2007;26:4725-9.
    PubMed     Related articles    Abstract available


  34. LEUPOLD JH , Yang HS, Colburn NH, Asangani I, et al
    Tumor suppressor Pdcd4 inhibits invasion/intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors.
    Oncogene. 2007;26:4550-62.
    PubMed     Related articles    Abstract available


  35. OLLIKAINEN M , Hannelius U, Lindgren CM, Abdel-Rahman WM, et al
    Mechanisms of inactivation of MLH1 in hereditary nonpolyposis colorectal carcinoma: a novel approach.
    Oncogene. 2007;26:4541-9.
    PubMed     Related articles    Abstract available


  36. KIM D , Rath O, Kolch W, Cho KH, et al
    A hidden oncogenic positive feedback loop caused by crosstalk between Wnt and ERK pathways.
    Oncogene. 2007;26:4571-9.
    PubMed     Related articles    Abstract available


    June 2007
  37. GROSS I , Duluc I, Benameur T, Calon A, et al
    The intestine-specific homeobox gene Cdx2 decreases mobility and antagonizes dissemination of colon cancer cells.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  38. DESNOYERS LR , Pai R, Ferrando RE, Hotzel K, et al
    Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


    May 2007
  39. PFEIFFER P , Qvortrup C, Eriksen JG
    Current role of antibody therapy in patients with metastatic colorectal cancer.
    Oncogene. 2007;26:3661-78.
    PubMed     Related articles    Abstract available


  40. GALIZIA G , Lieto E, De Vita F, Orditura M, et al
    Cetuximab, a chimeric human mouse anti-epidermal growth factor receptor monoclonal antibody, in the treatment of human colorectal cancer.
    Oncogene. 2007;26:3654-3660.
    PubMed     Related articles    Abstract available


  41. AOKI K , Aoki M, Sugai M, Harada N, et al
    Chromosomal instability by beta-catenin/TCF transcription in APC or beta-catenin mutant cells.
    Oncogene. 2007;26:3511-20.
    PubMed     Related articles    Abstract available


  42. KELLER JW , Haigis KM, Franklin JL, Whitehead RH, et al
    Oncogenic K-RAS subverts the antiapoptotic role of N-RAS and alters modulation of the N-RAS:gelsolin complex.
    Oncogene. 2007;26:3051-9.
    PubMed     Related articles    Abstract available


  43. MAMIDIPUDI V , Dhillon NK, Parman T, Miller LD, et al
    RACK1 inhibits colonic cell growth by regulating Src activity at cell cycle checkpoints.
    Oncogene. 2007;26:2914-24.
    PubMed     Related articles    Abstract available


    April 2007
  44. HUANG HC , Hu CH, Tang MC, Wang WS, et al
    Thymosin beta4 triggers an epithelial-mesenchymal transition in colorectal carcinoma by upregulating integrin-linked kinase.
    Oncogene. 2007;26:2781-90.
    PubMed     Related articles    Abstract available


  45. TARZE A , Deniaud A, Le Bras M, Maillier E, et al
    GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization.
    Oncogene. 2007;26:2606-20.
    PubMed     Related articles    Abstract available


  46. HURLEY PJ , Wilsker D, Bunz F
    Human cancer cells require ATR for cell cycle progression following exposure to ionizing radiation.
    Oncogene. 2007;26:2535-42.
    PubMed     Related articles    Abstract available


    March 2007
  47. WANG H , Yan C, Asangani I, Allgayer H, et al
    Identification of an histone H3 acetylated/K4-methylated-bound intragenic enhancer regulatory for urokinase receptor expression.
    Oncogene. 2007;26:2058-70.
    PubMed     Related articles    Abstract available


  48. ZAPATKA M , Zboralski D, Radacz Y, Bockmann M, et al
    Basement membrane component laminin-5 is a target of the tumor suppressor Smad4.
    Oncogene. 2007;26:1417-27.
    PubMed     Related articles    Abstract available


  49. OLIVA-TRASTOY M , Berthonaud V, Chevalier A, Ducrot C, et al
    The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase.
    Oncogene. 2007;26:1449-58.
    PubMed     Related articles    Abstract available


    February 2007
  50. CORRAL RS , Iniguez MA, Duque J, Lopez-Perez R, et al
    Bombesin induces cyclooxygenase-2 expression through the activation of the nuclear factor of activated T cells and enhances cell migration in Caco-2 colon carcinoma cells.
    Oncogene. 2007;26:958-69.
    PubMed     Related articles    Abstract available


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