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Diabetes

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Articles published in Diabetes
Retrieve available abstracts of 396 articles:
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Single Articles

May 2024

GUPTA OT, Gupta RK
The Expanding Problem of Regional Adiposity: Revisiting a 1985 Diabetes Classic by Ohlson et al.
Diabetes. 2024;73:649-652.
PubMed Abstract available

AMANDA DK
A Comparison of Daily Glucose Fluctuation Between GCK-MODY and Type 2 Diabetes Using Continuous Glucose Monitoring Technology. Diabetes 2023;72:812-818.
Diabetes. 2024;73:e1-e2.
PubMed

April 2024

YAMATO M, Kato N, Yamada KI, Inoguchi T, et al
The Early Pathogenesis of Diabetic Retinopathy and Its Attenuation by Sodium-Glucose Transporter 2 Inhibitors.
Diabetes. 2024 Apr 12:db220970. doi: 10.2337/db22-0970.
PubMed Abstract available

LI Y, Chen GC, Moon JY, Arthur R, et al
Genetic subtypes of prediabetes, healthy lifestyle, and risk of type 2 diabetes.
Diabetes. 2024 Apr 11:db230699. doi: 10.2337/db23-0699.
PubMed Abstract available

ASTRADA A
Comment on Pataky et al. Divergent Skeletal Muscle Metabolomic Signatures of Different Exercise Training Modes Independently Predict Cardiometabolic Risk Factors. Diabetes 2024;73:23-37.
Diabetes. 2024 Apr 9:db240033. doi: 10.2337/db24-0033.
PubMed

PURNELL JQ
Metabolic-Bariatric Surgery for Type 2 Diabetes: Time(ing) for a Change.
Diabetes. 2024;73:542-544.
PubMed

EVANS-MOLINA C
The Ailing beta-Cell in Diabetes: Insights From a Trip to the ER: The 2023 Outstanding Scientific Achievement Award Lecture.
Diabetes. 2024;73:545-553.
PubMed Abstract available

DRAWSHY Z, Neiman D, Fridlich O, Peretz A, et al
DNA Methylation-Based Assessment of Cell Composition in Human Pancreas and Islets.
Diabetes. 2024;73:554-564.
PubMed Abstract available

SLAK RUPNIK M, Hara M
Local Dialogues Between the Endocrine and Exocrine Cells in the Pancreas.
Diabetes. 2024;73:533-541.
PubMed Abstract available

SCHWEITZER N, Son SJ, Aizenstein H, Yang S, et al
Higher HbA1c Is Associated With Greater 2-Year Progression of White Matter Hyperintensities.
Diabetes. 2024;73:604-610.
PubMed Abstract available

DEVKOTA R, Small JC, Carbone K, Glass MA, et al
KD025 Is a Casein Kinase 2 Inhibitor That Protects Against Glucolipotoxicity in beta-Cells.
Diabetes. 2024;73:585-591.
PubMed Abstract available

March 2024

RAMOS SV, Distefano G, Lui LY, Cawthon PM, et al
Role of Cardiorespiratory Fitness and Mitochondrial Oxidative Capacity in Reduced Walk Speed of Older Adults with Diabetes.
Diabetes. 2024 Mar 29:db230827. doi: 10.2337/db23-0827.
PubMed Abstract available

ABRAHAM A, Cule M, Thanaj M, Basty N, et al
Genetic evidence for distinct biological mechanisms that link adiposity to type 2 diabetes: towards precision medicine.
Diabetes. 2024 Mar 26:db231005. doi: 10.2337/db23-1005.
PubMed Abstract available

WILLIAMS RC, Hanson RL, Peters B, Kearns K, et al
Epistasis Between HLA-DRB1*16:02:01 and SLC16A11 T-C-G-T-T Reduces Odds for Type 2 Diabetes in Southwest American Indians.
Diabetes. 2024 Mar 26:db230925. doi: 10.2337/db23-0925.
PubMed Abstract available

FAWAZ S, Martin Alonso A, Qiu Y, Ramnath R, et al
Adiponectin reduces glomerular endothelial glycocalyx disruption and restores glomerular barrier function in a mouse model of type 2 diabetes.
Diabetes. 2024 Mar 26:db230455. doi: 10.2337/db23-0455.
PubMed Abstract available

FAN Y, Chow E, Lim CKP, Hou Y, et al
Comparison of beta-cell function and insulin sensitivity between normal-weight and obese Chinese with young-onset type 2 diabetes.
Diabetes. 2024 Mar 20:db230966. doi: 10.2337/db23-0966.
PubMed Abstract available

XIE Y, Yuan Q, Tang B, Xie Y, et al
CPT1A Protects Podocytes from Lipotoxicity and Apoptosis In Vitro and Alleviates Diabetic Nephropathy In Vivo.
Diabetes. 2024 Mar 20:db230811. doi: 10.2337/db23-0811.
PubMed Abstract available

PEDERSEN FN, Stokholm L, Andersen N, Andresen J, et al
Risk of diabetic retinopathy according to subtype of type 2 diabetes.
Diabetes. 2024 Mar 18:db240016. doi: 10.2337/db24-0016.
PubMed Abstract available

IRVIN MR, Ge T, Patki A, Srinivasasainagendra V, et al
Polygenic Risk for Type 2 Diabetes in African Americans.
Diabetes. 2024 Mar 12:db230232. doi: 10.2337/db23-0232.
PubMed Abstract available

LEWIS GF, Mulvihill EE
The Complexities of Intestinal Lipoprotein Production in Insulin Resistance and Diabetes: Revisiting a 2010 Diabetes Classic by Pavlic et al.
Diabetes. 2024;73:335-337.
PubMed

RIERA CE
Wiring the Brain for Wellness: Sensory Integration in Feeding and Thermogenesis: A Report on Research Supported by Pathway to Stop Diabetes.
Diabetes. 2024;73:338-347.
PubMed Abstract available

GUO Q, Gao Z, Zhao L, Wang H, et al
Multiomics Analyses With Stool-Type Stratification in Patient Cohorts and Blautia Identification as a Potential Bacterial Modulator in Type 2 Diabetes Mellitus.
Diabetes. 2024;73:511-527.
PubMed Abstract available

COYKENDALL VMN, Qian MF, Tellez K, Bautista A, et al
RFX6 Maintains Gene Expression and Function of Adult Human Islet alpha-Cells.
Diabetes. 2024;73:448-460.
PubMed Abstract available

SAKURAI Y, Kubota N, Takamoto I, Wada N, et al
Overexpression of UBE2E2 in Mouse Pancreatic beta-Cells Leads to Glucose Intolerance via Reduction of beta-Cell Mass.
Diabetes. 2024;73:474-489.
PubMed Abstract available

CAO C, Koh HE, Reeds DN, Patterson BW, et al
Critical Evaluation of Indices Used to Assess beta-Cell Function.
Diabetes. 2024;73:391-400.
PubMed Abstract available

KIM YK, Kim YR, Wells KL, Sarbaugh D, et al
PTPN2 Regulates Metabolic Flux to Affect beta-Cell Susceptibility to Inflammatory Stress.
Diabetes. 2024;73:434-447.
PubMed Abstract available

ASLAMY A, Wood AC, Jensen ET, Bertoni AG, et al
Increased Plasma Branched Short-Chain Fatty Acids and Improved Glucose Homeostasis: The Microbiome and Insulin Longitudinal Evaluation Study (MILES).
Diabetes. 2024;73:385-390.
PubMed Abstract available

February 2024

LI D, Hsu FC, Palmer ND, Liu L, et al
Multi-omics Analyses Identify AKR1A1 as a Biomarker for Diabetic Kidney Disease.
Diabetes. 2024 Feb 23:db230540. doi: 10.2337/db23-0540.
PubMed Abstract available

HAN X, Wei J, Zheng R, Tu Y, et al
Macrophage SHP2 Deficiency Alleviates Diabetic Nephropathy via Suppression of MAPK/NF-kB-Dependent Inflammation.
Diabetes. 2024 Feb 23:db230700. doi: 10.2337/db23-0700.
PubMed Abstract available

KASINATHAN D, Guo Z, Sarver DC, Wong GW, et al
Cell-surface ZnT8 antibody prevents and reverses autoimmune diabetes in mice.
Diabetes. 2024 Feb 22:db230568. doi: 10.2337/db23-0568.
PubMed Abstract available

ROBERTSON RP
Brief Review and Perspective: Antioxidants for early treatment of Type 2 Diabetes in Rodents and Humans: Lost in Translation?
Diabetes. 2024 Feb 22:db230901. doi: 10.2337/db23-0901.
PubMed Abstract available

HEATHER LC, Gopal K, Srnic N, Ussher JR, et al
Redefining Diabetic Cardiomyopathy: Perturbations in Substrate Metabolism at the Heart of its Pathology.
Diabetes. 2024 Feb 22:dbi230019. doi: 10.2337/dbi23-0019.
PubMed Abstract available

CALLEBAUT A, Guyer P, Derua R, Buitinga M, et al
CD4+ T cells from individuals with type 1 diabetes respond to a novel class of deamidated peptides formed in pancreatic islets.
Diabetes. 2024 Feb 22:db230588. doi: 10.2337/db23-0588.
PubMed Abstract available

LATRES E, Greenbaum CJ, Oyaski ML, Dayan CM, et al
Evidence for C-peptide as a Validated Surrogate to Predict Clinical Benefits in Trials of Disease-Modifying Therapies for Type 1 Diabetes.
Diabetes. 2024 Feb 13:dbi230012. doi: 10.2337/dbi23-0012.
PubMed Abstract available

GUO L, Pan Q, Cheng Z, Li Z, et al
Acetyllevocarnitine hydrochloride for the treatment of diabetic peripheral neuropathy: A phase 3, randomized clinical trial in China.
Diabetes. 2024 Feb 6:db230377. doi: 10.2337/db23-0377.
PubMed Abstract available

GARCIA-PENA LM, Abel ED, Pereira RO
Mitochondrial Dynamics, Diabetes, and Cardiovascular Disease.
Diabetes. 2024;73:151-161.
PubMed Abstract available

GILANI A, Stoll L, Homan EA, Lo JC, et al
Adipose Signals Regulating Distal Organ Health and Disease.
Diabetes. 2024;73:169-177.
PubMed Abstract available

FERRANNINI E, Solini A, Baldi S, Scozzaro T, et al
Role of Glycosuria in SGLT2 Inhibitor-Induced Cardiorenal Protection: A Mechanistic Analysis of the CREDENCE Trial.
Diabetes. 2024;73:250-259.
PubMed Abstract available

KHAFAGY R, Paterson AD, Dash S
Erythritol as a Potential Causal Contributor to Cardiometabolic Disease: A Mendelian Randomization Study.
Diabetes. 2024;73:325-331.
PubMed Abstract available

January 2024

CALLEBAUT A, Guyer P, Baker RL, Gallegos JB, et al
An Insulin-Chromogranin A Hybrid Peptide activates DR11 restricted T cells in human type 1 diabetes.
Diabetes. 2024 Jan 31:db230622. doi: 10.2337/db23-0622.
PubMed Abstract available

CIOU JJ, Chien MW, Hsu CY, Liu YW, et al
Excess Salt Intake Activates IL-21-dominant Autoimmune Diabetogenesis via A Saltregulated Ste20-related Proline/alanine-rich Kinase in CD4 T Cells.
Diabetes. 2024 Jan 19:db230599. doi: 10.2337/db23-0599.
PubMed Abstract available

WYATT RC, Grace SL, Brigatti C, Marzinotto I, et al
Improved specificity of glutamate decarboxylase 65 autoantibody measurement using luciferase-based immunoprecipitation system (LIPS) assays.
Diabetes. 2024 Jan 17:db230550. doi: 10.2337/db23-0550.
PubMed Abstract available

BACHA F, El-Ayash H, Mohamad M, Sharma S, et al
Distinct Amino Acid Profile Characterizes Youth with or at risk for Type 2 Diabetes.
Diabetes. 2024 Jan 12:db230375. doi: 10.2337/db23-0375.
PubMed Abstract available

ZHANG W, Ma L, Zhou Q, Gu T, et al
Therapeutic targets for diabetic kidney disease: proteome-wide Mendelian randomization and colocalization analyses.
Diabetes. 2024 Jan 11:db230564. doi: 10.2337/db23-0564.
PubMed Abstract available

COHRS CM, Chen C, Atkinson MA, Drotar DM, et al
Bridging the Gap: Pancreas Tissue Slices From Organ and Tissue Donors for the Study of Diabetes Pathogenesis.
Diabetes. 2024;73:11-22.
PubMed Abstract available

JIMENEZ-SANCHEZ C, Sinturel F, Mezza T, Loizides-Mangold U, et al
Lysophosphatidylinositols Are Upregulated After Human beta-Cell Loss and Potentiate Insulin Release.
Diabetes. 2024;73:93-107.
PubMed Abstract available

ZHOU Y, Liu K, Tang W, Zhang Y, et al
beta-Cell miRNA-503-5p Induced by Hypomethylation and Inflammation Promotes Insulin Resistance and beta-Cell Decompensation.
Diabetes. 2024;73:57-74.
PubMed Abstract available

December 2023

JIN R, Wang J, Li M, Tang T, et al
Discovery of a novel benzothiadiazine-based selective aldose reductase inhibitor as potential therapy for diabetic peripheral neuropathy.
Diabetes. 2023 Dec 21:db230006. doi: 10.2337/db23-0006.
PubMed Abstract available

D'ALESSIO DA, Marks V
Glucagon as the First Incretin: Objects (in the Rearview Mirror) Are Closer Than They Appear.
Diabetes. 2023;72:1739-1740.
PubMed

OKUNO T, Vansomphone A, Zhang E, Zhou H, et al
Association of Both Short-term and Long-term Glycemic Variability With the Development of Microalbuminuria in the ACCORD Trial.
Diabetes. 2023;72:1864-1869.
PubMed Abstract available

NOGAL A, Tettamanzi F, Dong Q, Louca P, et al
A Fecal Metabolite Signature of Impaired Fasting Glucose: Results From Two Independent Population-Based Cohorts.
Diabetes. 2023;72:1870-1880.
PubMed Abstract available

LUK CT, Chan CK, Chiu F, Shi SY, et al
Dual Role of Caspase 8 in Adipocyte Apoptosis and Metabolic Inflammation.
Diabetes. 2023;72:1751-1765.
PubMed Abstract available

November 2023

KUGATHASAN L, Sridhar VS, Lovblom LE, Matta S, et al
Interactive effects of Empagliflozin and Hyperglycemia on Urinary Amino Acids in Individuals with Type 1 Diabetes.
Diabetes. 2023 Nov 28:db230694. doi: 10.2337/db23-0694.
PubMed Abstract available

RASMUSSEN IKB, Skriver-Moeller AC, Ripa RS, Hasbak P, et al
Increased sub-clinical coronary artery pathology in type 2 diabetes with albuminuria.
Diabetes. 2023 Nov 22:db230529. doi: 10.2337/db23-0529.
PubMed Abstract available

CHANDRAKUMAR S, Santiago Tierno I, Agarwal M, Lessieur EM, et al
Mechanical regulation of retinal vascular inflammation and degeneration in diabetes.
Diabetes. 2023 Nov 21:db230584. doi: 10.2337/db23-0584.
PubMed Abstract available

YAO X, Zhao Z, Zhang W, Liu R, et al
Specialized Retinal Endothelial Cells Modulates Blood-Retina- Barrier in Diabetic Retinopathy.
Diabetes. 2023 Nov 17:db230368. doi: 10.2337/db23-0368.
PubMed Abstract available

LAI SWT, Hernandez-Castillo C, De Jesus Lopez Gonzalez E, Zoukari T, et al
Methylglyoxal adducts are prognostic biomarkers for diabetic kidney disease in patients with type 1 diabetes.
Diabetes. 2023 Nov 15:db230277. doi: 10.2337/db23-0277.
PubMed Abstract available

KELLER MP, O'Connor C, Bitzer M, Schueler KL, et al
Genetic analysis of obesity-induced diabetic nephropathy in BTBR mice.
Diabetes. 2023 Nov 7:db230444. doi: 10.2337/db23-0444.
PubMed Abstract available

STEFFEN BT, McDonough DJ, Pankow JS, Tang W, et al
Plasma neuronal growth regulator 1 may link physical activity to reduced risk of type 2 diabetes: a proteome-wide study of ARIC participants.
Diabetes. 2023 Nov 7:db230383. doi: 10.2337/db23-0383.
PubMed Abstract available

ILONEN J, Kiviniemi M, El-Amir MI, Nygard L, et al
Increased Frequency of the HLA-DRB1*04:04-DQA1*03-DQB1*03:02 Haplotype among HLA-DQB1*06:02 Positive Children with Type 1 Diabetes.
Diabetes. 2023 Nov 7:db230387. doi: 10.2337/db23-0387.
PubMed Abstract available

ELGAMAL RM, Kudtarkar P, Melton RL, Mummey HM, et al
An Integrated Map of Cell Type-Specific Gene Expression in Pancreatic Islets.
Diabetes. 2023;72:1719-1728.
PubMed Abstract available

October 2023

WRIGHT JJ, Eskaros A, Windon A, Bottino R, et al
Exocrine pancreas in type 1 and type 2 diabetes: different patterns of fibrosis, metaplasia, angiopathy, and adiposity.
Diabetes. 2023 Oct 26:db230009. doi: 10.2337/db23-0009.
PubMed Abstract available

YANG B, Alimperti S, Gonzalez MV, Dentchev T, et al
Re-epithelialization of Diabetic Skin and Mucosal Wounds is Rescued by Treatment with Epigenetic Inhibitors.
Diabetes. 2023 Oct 24:db230258. doi: 10.2337/db23-0258.
PubMed Abstract available

MASHAYEKHI M, Nian H, Mayfield D, Devin JK, et al
Weight Loss-Independent Effect of Liraglutide on Insulin Sensitivity in Individuals with Obesity and Pre-Diabetes.
Diabetes. 2023 Oct 24:db230356. doi: 10.2337/db23-0356.
PubMed Abstract available

MOTOMURA K, Matsuzaka T, Shichino S, Ogawa T, et al
Single-cell transcriptome profiling of pancreatic islets from early diabetic mice identifies Anxa10 for Ca2+ allostasis toward beta-cell failure.
Diabetes. 2023 Oct 23:db230212. doi: 10.2337/db23-0212.
PubMed Abstract available

Expression of Concern. Marciane Milanski, Ana P. Arruda, Andressa Coope, Leticia M. Ignacio-Souza, Carla E. Nunez, Erika A. Roman, Talita Romanatto, Livia B. Pascoal, Andrea M. Caricilli, Marcio A. Torsoni, Patricia O. Prada, Mario J. Saad, and Licio
Diabetes. 2023 Oct 23:db23ec12c. doi: 10.2337.
PubMed Abstract available

Expression of Concern. Marco A. Carvalho-Filho, Mirian Ueno, Sandro M. Hirabara, Amedea B. Seabra, Jose B.C. Carvalheira, Marcelo G. de Oliveira, Licio A. Velloso, Rui Curi, and Mario J.A. Saad. S-Nitrosation of the Insulin Receptor, Insulin Receptor
Diabetes. 2023 Oct 23:db23ec12a. doi: 10.2337.
PubMed Abstract available

Expression of Concern. Henrique G. Zecchin, Fernanda B.M. Priviero, Claudio T. Souza, Karina G. Zecchin, Patricia O. Prada, Jose B.C. Carvalheira, Licio A. Velloso, Edson Antunes, and Mario J.A. Saad. Defective Insulin and Acetylcholine Induction of E
Diabetes. 2023 Oct 23:db23ec12b. doi: 10.2337.
PubMed Abstract available

Expression of Concern. Eduardo R. Ropelle, Jose R. Pauli, Dennys E. Cintra, Adelino S. da Silva, Claudio T. De Souza, Dioze Guadagnini, Bruno M. Carvalho, Andrea M. Caricilli, Carlos K. Katashima, Marco A. Carvalho-Filho, Sandro Hirabara, Rui Curi, Li
Diabetes. 2023 Oct 23:db23ec12d. doi: 10.2337.
PubMed Abstract available

BERETTA M, Dai Y, Olzomer EM, Vancuylenburg CS, et al
Liver-selective imidazolopyrazine mitochondrial uncoupler SHD865 reverses adiposity and glucose intolerance in mice.
Diabetes. 2023 Oct 23:db230233. doi: 10.2337/db23-0233.
PubMed Abstract available

TSILINGIRIS D, Schimpfle L, Rauchhaupt EV, Sulaj A, et al
Sensory phenotypes provide insight into the natural course of diabetic polyneuropathy.
Diabetes. 2023 Oct 20:db230271. doi: 10.2337/db23-0271.
PubMed Abstract available

ZOU W, Chezhian J, Yu T, Liu W, et al
Dissecting the roles of the nuclear and mitochondrial genomes in a mouse model of autoimmune diabetes.
Diabetes. 2023 Oct 17:db230430. doi: 10.2337/db23-0430.
PubMed Abstract available

XU G, Chen J, Lu B, Sethupathy P, et al
Verapamil Prevents Decline of IGF-I in Subjects With Type 1 Diabetes and Promotes beta-Cell IGF-I Signaling.
Diabetes. 2023;72:1460-1469.
PubMed Abstract available

CHU Y, Zhao L, Liu X, Chen H, et al
Lysine 117 Residue Is Essential for the Function of the Hepatocyte Nuclear Factor 1alpha.
Diabetes. 2023;72:1502-1516.
PubMed Abstract available

September 2023

GUNES A, Schmitt C, Bilodeau L, Huet C, et al
IL-6 trans-signaling is increased in diabetes, impacted by glucolipotoxicity and associated with liver stiffness and fibrosis in fatty liver disease.
Diabetes. 2023 Sep 27:db230171. doi: 10.2337/db23-0171.
PubMed Abstract available

PEDERSEN FN, Stokholm L, Lois N, Yang D, et al
Structural and metabolic retinal changes associated with mild cognitive impairment in type 2 diabetes.
Diabetes. 2023 Sep 19:db230025. doi: 10.2337/db23-0025.
PubMed Abstract available

BOHOVYK R, Khedr S, Levchenko V, Stefanenko M, et al
Protease-Activated Receptor 1 Mediated Damage of Podocytes in Diabetic Nephropathy.
Diabetes. 2023 Sep 18:db230032. doi: 10.2337/db23-0032.
PubMed Abstract available

BOGDANOV P, Duarri A, Sabater D, Salas A, et al
Blocking hemopexin with specific antibodies: a new strategy for treating diabetic retinopathy.
Diabetes. 2023 Sep 18:db230027. doi: 10.2337/db23-0027.
PubMed Abstract available

OBERHAUSER SS, l'Allemand D, Willems EP, Gozzi T, et al
The slowing of peripheral nerve conduction velocity in children and adolescents with type 1 diabetes is predicted by glucose fluctuations.
Diabetes. 2023 Sep 12:db230063. doi: 10.2337/db23-0063.
PubMed Abstract available

PARVEEN N, Wang JK, Bhattacharya S, Cuala J, et al
Erratum. DNA Methylation-Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic beta-Cell Heterogeneity. Diabetes 2023;72:575-589.
Diabetes. 2023 Sep 8:db23er12a. doi: 10.2337.
PubMed Abstract available

COSTES S, Huang CJ, Gurlo T, Daval M, et al
Erratum. beta-Cell Dysfunctional ERAD/Ubiquitin/Proteasome System in Type 2 Diabetes Mediated by Islet Amyloid Polypeptide-Induced UCH-L1 Deficiency. Diabetes 2011;60:227-238.
Diabetes. 2023 Sep 8:db23er12. doi: 10.2337.
PubMed Abstract available

SONG L, Chang X, Hu L, Liu L, et al
Accelerating Wound Closure with Metrnl in Normal and Diabetic Mouse Skin.
Diabetes. 2023 Sep 8:db230173. doi: 10.2337/db23-0173.
PubMed Abstract available

D'ALESSIO D
Classics in Diabetes.
Diabetes. 2023;72:1179.
PubMed

PAN Q, Ai W, Chen Y, Kim DM, et al
Reciprocal Regulation of Hepatic TGF-beta1 and Foxo1 Controls Gluconeogenesis and Energy Expenditure.
Diabetes. 2023;72:1193-1206.
PubMed Abstract available

LANG AL, Nissanka N, Louzada RA, Tamayo A, et al
A Defect in Mitochondrial Complex III but Not in Complexes I or IV Causes Early beta-Cell Dysfunction and Hyperglycemia in Mice.
Diabetes. 2023;72:1262-1276.
PubMed Abstract available

August 2023

RUSS-SILSBY J, Patel KA, Laver TW, Hawkes G, et al
The Role of ONECUT1 Variants in Monogenic and Type 2 Diabetes Mellitus.
Diabetes. 2023 Aug 28:db230498. doi: 10.2337/db23-0498.
PubMed Abstract available

THIRAWATANANOND P, Brown ME, Sachs LK, Arnoletti JM, et al
Treg-specific CD226 Deletion Reduces Diabetes Incidence in NOD Mice by Improving Regulatory T Cell Stability.
Diabetes. 2023 Aug 25:db230307. doi: 10.2337/db23-0307.
PubMed Abstract available

FOTINO C, Molano RD, Nasr MB, Umland O, et al
Reversal of experimental autoimmune diabetes with a sCD39/anti-CD3 treatment.
Diabetes. 2023 Aug 25:db230178. doi: 10.2337/db23-0178.
PubMed Abstract available

SAULNIER PJ, Looker HC, Layton A, Lemley KV, et al
Loss of Glomerular Permselectivity in Type 2 Diabetes Associates with Progression to Kidney Failure.
Diabetes. 2023 Aug 16:db230310. doi: 10.2337/db23-0310.
PubMed Abstract available

WU J, Wang Z, Cai M, Wang X, et al
GPR56 promotes diabetic kidney disease through eNOS regulation in glomerular endothelial cells.
Diabetes. 2023 Aug 14:db230124. doi: 10.2337/db23-0124.
PubMed Abstract available

ZHANG W, Zhang L, Zhu J, Xiao C, et al
Additional Evidence for the Relationship between Type 2 Diabetes Mellitus and Stroke through Observational and Genetic Analyses.
Diabetes. 2023 Aug 8:db220954. doi: 10.2337/db22-0954.
PubMed Abstract available

ZHANG X, Zhang F
Peripheral Neuropathy in Diabetes: What Can MRI Do?
Diabetes. 2023;72:1060-1069.
PubMed Abstract available

ZHANG F, Baranova A
Response to Comment on Baranova et al. Causal Associations Between Basal Metabolic Rate and COVID-19. Diabetes 2023;72:149-154.
Diabetes. 2023;72:e8.
PubMed

KLOECKER DE, Brage S, Wareham NJ
Comment on Baranova et al. Causal Associations Between Basal Metabolic Rate and COVID-19. Diabetes 2023;72:149-154.
Diabetes. 2023;72:e6-e7.
PubMed

TRISCHITTA V, Menzaghi C, Copetti M
Unveiling Novel Markers and Modeling Clinical Prediction of Treatment Effects Are Equally Important for Implementing Precision Therapeutics.
Diabetes. 2023;72:1057-1059.
PubMed

OGER F, Bourouh C, Friano ME, Courty E, et al
beta-Cell-Specific E2f1 Deficiency Impairs Glucose Homeostasis, beta-Cell Identity, and Insulin Secretion.
Diabetes. 2023;72:1112-1126.
PubMed Abstract available

PATEL V, Sarkar P, Siegel DM, Teegala SB, et al
The Antinarcolepsy Drug Modafinil Reverses Hypoglycemia Unawareness and Normalizes Glucose Sensing of Orexin Neurons in Male Mice.
Diabetes. 2023;72:1144-1153.
PubMed Abstract available

RIAL SA, Shishani R, Cummings BP, Lim GE, et al
Is 14-3-3 the Combination to Unlock New Pathways to Improve Metabolic Homeostasis and beta-Cell Function?
Diabetes. 2023;72:1045-1054.
PubMed Abstract available

ZHANG H, Mulya A, Nieuwoudt S, Vandanmagsar B, et al
GDF15 Mediates the Effect of Skeletal Muscle Contraction on Glucose-Stimulated Insulin Secretion.
Diabetes. 2023;72:1070-1082.
PubMed Abstract available

July 2023

SASSI G, Licata G, Ventriglia G, Wouters A, et al
A plasma miR-193b-365 signature combined with age and glycemic status predicts response to Lactococcus lactis-based antigen-specific immunotherapy in new-onset type 1 diabetes.
Diabetes. 2023 Jul 26:db220852. doi: 10.2337/db22-0852.
PubMed Abstract available

WRETLIND A, Curovic VR, Suvitaival T, Theilade S, et al
Ceramides as risk markers for future cardiovascular events and all-cause mortality in long-standing type 1 diabetes.
Diabetes. 2023 Jul 21:db230052. doi: 10.2337/db23-0052.
PubMed Abstract available

SCHON M, Zaharia OP, Strassburger K, Kupriyanova Y, et al
Intramyocellular Triglyceride Content During the Early Course of Type 1 and Type 2 Diabetes Mellitus.
Diabetes. 2023 Jul 21:db230353. doi: 10.2337/db23-0353.
PubMed Abstract available

TANG Y, Ang L, Jaiswal M, Dillon BR, et al
Cardiovascular autonomic neuropathy and risk of kidney function decline in type 1 and type 2 diabetes: findings from the PERL and ACCORD cohorts.
Diabetes. 2023 Jul 19:db230247. doi: 10.2337/db23-0247.
PubMed Abstract available

LUCIDI P, Perriello G, Porcellati F, Pampanelli S, et al
DIURNAL CYCLING OF INSULIN SENSITIVITY IN TYPE 2 DIABETES: EVIDENCE FOR DEVIATION FROM PHYSIOLOGY AT AN EARLY STAGE.
Diabetes. 2023 Jul 13:db220721. doi: 10.2337/db22-0721.
PubMed Abstract available

SIMO R, Hernandez C
Fenofibrate for Treating Diabetic Eye Disease.
Diabetes. 2023;72:838-840.
PubMed

JANDELEIT-DAHM K, Meister J
Cytochrome-Derived EETs, VEGF-A, and NOX4: Piecing the Puzzle Together.
Diabetes. 2023;72:841-843.
PubMed

LIU L, Wess J
Adipocyte G Protein-Coupled Receptors as Potential Targets for Novel Antidiabetic Drugs.
Diabetes. 2023;72:825-834.
PubMed Abstract available

ZARINI S, Zemski Berry KA, Kahn DE, Garfield A, et al
Deoxysphingolipids: Atypical Skeletal Muscle Lipids Related to Insulin Resistance in Humans That Decrease Insulin Sensitivity In Vitro.
Diabetes. 2023;72:884-897.
PubMed Abstract available

XU Z, Yang J, Zheng H, Xie T, et al
Long Noncoding RNA PPT2-EGFL8 Regulates Pathological Retinal Neovascularization in PDR by Functioning as a Competing Endogenous RNA.
Diabetes. 2023;72:1012-1027.
PubMed Abstract available

DONG L, Cheng R, Ma X, Liang W, et al
Regulation of Monocyte Activation by PPARalpha Through Interaction With the cGAS-STING Pathway.
Diabetes. 2023;72:958-972.
PubMed Abstract available

June 2023

GITELMAN SE, Evans-Molina C, Guolo A, Mari A, et al
ss-cell glucose sensitivity to assess changes in ss-cell function in recent onset stage 3 type 1 diabetes.
Diabetes. 2023 Jun 27:db230196. doi: 10.2337/db23-0196.
PubMed Abstract available

CHEN YC, Taylor AJ, Fulcher JM, Swensen AC, et al
Deletion of carboxypeptidase E in beta cells disrupts proinsulin processing but does not lead to spontaneous development of diabetes in mice.
Diabetes. 2023 Jun 26:db220945. doi: 10.2337/db22-0945.
PubMed Abstract available

SZILI-TOROK T, de Borst MH, Garcia E, Gansevoort RT, et al
Fasting ketone bodies and incident type 2 diabetes in the general population.
Diabetes. 2023 Jun 23:db220826. doi: 10.2337/db22-0826.
PubMed Abstract available

LUO JY, Cheng CK, Gou L, He L, et al
Induction of KLF2 by exercise activates eNOS to improve vasodilatation in diabetic mice.
Diabetes. 2023 Jun 22:db230070. doi: 10.2337/db23-0070.
PubMed Abstract available

HU Z, Wang J, Pan T, Li X, et al
The exosome-transmitted lncRNA LOC100132249 induces endothelial dysfunction in diabetic retinopathy.
Diabetes. 2023 Jun 22:db220435. doi: 10.2337/db22-0435.
PubMed Abstract available

SAKO S, Takeshita Y, Takayama H, Goto H, et al
Trajectories of liver fibrosis and gene expression profiles in NAFLD associated with diabetes.
Diabetes. 2023 Jun 21:db220933. doi: 10.2337/db22-0933.
PubMed Abstract available

Statement of Retraction. Timothy Dunn, Yongjin Xu, Sharon Schneider, Susan Gawel, Rajkamal Gopinath, Marvin Berman, and Anthony P. Orzechowski. 1106-P: Real-World Confirmation of the Nonlinear Relationship Between Glucose and Glycated Hemoglobin. Diab
Diabetes. 2023 Jun 7:db23rt08a. doi: 10.2337.
PubMed Abstract available

QURESHI FM, Panzer JK, Poder J, Malek TR, et al
Immunotherapy With Low-Dose IL-2/CD25 Prevents beta-Cell Dysfunction and Dysglycemia in Prediabetic NOD Mice.
Diabetes. 2023;72:769-780.
PubMed Abstract available

ROJAS-CANALES D, Walters SN, Penko D, Cultrone D, et al
Intracutaneous Transplantation of Islets Within a Biodegradable Temporizing Matrix as an Alternative Site for Islet Transplantation.
Diabetes. 2023;72:758-768.
PubMed Abstract available

DAVIDSON RK, Kanojia S, Wu W, Kono T, et al
The Chd4 Helicase Regulates Chromatin Accessibility and Gene Expression Critical for beta-Cell Function In Vivo.
Diabetes. 2023;72:746-757.
PubMed Abstract available

MONTGOMERY MK, Bayliss J, Nie S, de Nardo W, et al
Liver-Secreted Hexosaminidase A Regulates Insulin-Like Growth Factor Signaling and Glucose Transport in Skeletal Muscle.
Diabetes. 2023;72:715-727.
PubMed Abstract available

ASHCROFT FM
KATP Channels and the Metabolic Regulation of Insulin Secretion in Health and Disease: The 2022 Banting Medal for Scientific Achievement Award Lecture.
Diabetes. 2023;72:693-702.
PubMed Abstract available

May 2023

POSTIC S, Pfabe J, Sarikas S, Ehall B, et al
Tracking Ca2+ dynamics in NOD mouse islets during spontaneous diabetes development.
Diabetes. 2023 May 31:db220952. doi: 10.2337/db22-0952.
PubMed Abstract available

HUANG X, Zhao Y, Liu T, Wu D, et al
beta-cell function and insulin dynamics in obese patients with and without diabetes after sleeve gastrectomy.
Diabetes. 2023 May 31:db221048. doi: 10.2337/db22-1048.
PubMed Abstract available

BODE K, MacDonald T, Stewart T, Mendez B, et al
Protective Renalase-deficiency in beta cells shapes immune metabolism and function in autoimmune diabetes.
Diabetes. 2023 May 22:db230030. doi: 10.2337/db23-0030.
PubMed Abstract available

NGUYEN A, Khafagy R, Gao Y, Meerasa A, et al
Erratum. Association Between Obesity and Chronic Kidney Disease: Multivariable Mendelian Randomization Analysis and Observational Data From a Bariatric Surgery Cohort. Diabetes 2023;72:496-510.
Diabetes. 2023 May 18:db23er08a. doi: 10.2337.
PubMed Abstract available

Statement of Retraction. Yu Zhao, Jiliang Wu, Huaiping Zhu, Ping Song, and Ming-Hui Zou. Peroxynitrite-Dependent Zinc Release and Inactivation of Guanosine 5'-Triphosphate Cyclohydrolase 1 Instigate Its Ubiquitination in Diabetes. Diabetes 2013;62:424
Diabetes. 2023 May 15:db23rt07c. doi: 10.2337.
PubMed Abstract available

Expression of Concern. Yunzhou Dong, Miao Zhang, Shuangxi Wang, Bin Liang, Zhengxing Zhao, Chao Liu, Mingyuan Wu, Hyoung Chul Choi, Timothy J. Lyons, and Ming-Hui Zou. Activation of AMP-Activated Protein Kinase Inhibits Oxidized LDL-Triggered Endoplas
Diabetes. 2023 May 15:db23ec07a. doi: 10.2337.
PubMed Abstract available

Expression of Concern. Chaoyong He, Hongliang Li, Benoit Viollet, Ming-Hui Zou, and Zhonglin Xie. AMPK Suppresses Vascular Inflammation In Vivo by Inhibiting Signal Transducer and Activator of Transcription-1. Diabetes 2015;64:4285-4297. DOI: 10.2337/
Diabetes. 2023 May 15:db23ec07c. doi: 10.2337.
PubMed Abstract available

Expression of Concern. Shuangxi Wang, Jian Xu, Ping Song, Benoit Viollet, and Ming-Hui Zou. In Vivo Activation of AMP-Activated Protein Kinase Attenuates Diabetes-Enhanced Degradation of GTP Cyclohydrolase I. Diabetes 2009;58:1893-1901. DOI: 10.2337/d
Diabetes. 2023 May 15:db23ec07b. doi: 10.2337.
PubMed Abstract available

YAN C, Tian X, Li J, Liu D, et al
Erratum. A High-Fat Diet AMPK alpha1 in Adipocytes to Induce Exosome Shedding and Nonalcoholic Fatty Liver Development In Vivo. Diabetes 2021;70:577-588.
Diabetes. 2023 May 15:db23er07. doi: 10.2337.
PubMed Abstract available

Statement of Retraction. Wencheng Zhang, Qilong Wang, Ping Song, and Ming-Hui Zou. Liver Kinase B1 Is Required for White Adipose Tissue Growth and Differentiation. Diabetes 2013;62:2347-2358. DOI: 10.2337/db12-1229. PMID: 23396401. PMCID: PMC3712073.
Diabetes. 2023 May 15:db23rt07b. doi: 10.2337.
PubMed Abstract available

Statement of Retraction. Zhonglin Xie, Junhua Zhang, Jiliang Wu, Benoit Viollet, and Ming-Hui Zou. Upregulation of Mitochondrial Uncoupling Protein-2 by the AMP-Activated Protein Kinase in Endothelial Cells Attenuates Oxidative Stress in Diabetes. Dia
Diabetes. 2023 May 15:db23rt07a. doi: 10.2337.
PubMed Abstract available

MONTEFUSCO L, Pastore I, Lunati ME, Fiorina P, et al
Increased Risk of Diabetes and Diabetic Ketoacidosis Associated With COVID-19.
Diabetes. 2023;72:560-561.
PubMed

MEMON B, Abdelalim EM
Comment on Carrasco et al. Spatial Environment Affects HNF4A Mutation-Specific Proteome Signatures and Cellular Morphology in hiPSC-Derived beta-Like Cells. Diabetes 2022;71:862-869.
Diabetes. 2023;72:e1-e2.
PubMed

REYNOLDS GP
Comment on Tabatabaei Dakhili et al. The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase. Diabetes 2023;72:126-134.
Diabetes. 2023;72:e5.
PubMed

SCHOLZ H, Raeder H
Response to Comment on Carrasco et al. Spatial Environment Affects HNF4A Mutation-Specific Proteome Signatures and Cellular Morphology in hiPSC-Derived beta-Like Cells. Diabetes 2022;71:862-869.
Diabetes. 2023;72:e3-e4.
PubMed

PUTMAN MS, Norris AW, Hull RL, Rickels MR, et al
Cystic Fibrosis-Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes.
Diabetes. 2023 May 1:db220949. doi: 10.2337/db22-0949.
PubMed Abstract available

ALONGE KM, Porte D, Schwartz MW
Distinct Roles for Brain and Pancreas in Basal and Postprandial Glucose Homeostasis.
Diabetes. 2023;72:547-556.
PubMed Abstract available

WESTERMAN KE, Walker ME, Gaynor SM, Wessel J, et al
Investigating Gene-Diet Interactions Impacting the Association Between Macronutrient Intake and Glycemic Traits.
Diabetes. 2023;72:653-665.
PubMed Abstract available

April 2023

MASTRACCI TL, Apte M, Amundadottir LT, Alvarsson A, et al
Erratum. Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. Diabetes 2023;72:433-448.
Diabetes. 2023 Apr 28:db23er08. doi: 10.2337.
PubMed Abstract available

HSU CC, Fidler TP, Kanter JE, Kothari V, et al
Hematopoietic NLRP3 and AIM2 inflammasomes promote diabetes-accelerated atherosclerosis, but increased necrosis is independent of pyroptosis.
Diabetes. 2023 Apr 21:db220962. doi: 10.2337/db22-0962.
PubMed Abstract available

TI Y, Xie GL, Wang ZH, Bi XL, et al
Erratum. TRB3 Gene Silencing Alleviates Diabetic Cardiomyopathy in a Type 2 Diabetic Rat Model. Diabetes 2011;60:2963-2974.
Diabetes. 2023 Apr 18:db23er06a. doi: 10.2337.
PubMed Abstract available

JANSEN TJP, Buitinga M, Boss M, Nijhoff MF, et al
Monitoring beta cell survival after intrahepatic islet transplantation using dynamic exendin PET imaging: a proof-of-concept study in individuals with type 1 diabetes.
Diabetes. 2023 Apr 17:db220884. doi: 10.2337/db22-0884.
PubMed Abstract available

YANG D, Patel S, Szlachcic WJ, Chmielowiec J, et al
Erratum. Pancreatic Differentiation of Stem Cells Reveals Pathogenesis of a Syndrome of Ketosis-Prone Diabetes. Diabetes 2021;70:2419-2429.
Diabetes. 2023 Apr 17:db23er06b. doi: 10.2337.
PubMed Abstract available

CHANDRAKUMAR S, Tierno IS, Agarwal M, Matisioudis N, et al
Subendothelial matrix stiffening by lysyl oxidase enhances RAGE-mediated retinal endothelial activation in diabetes.
Diabetes. 2023 Apr 14:db220761. doi: 10.2337/db22-0761.
PubMed Abstract available

SHINJO T, Onizuka S, Zaitsu Y, Ishikado A, et al
Dysregulation of CXCL1 expression and neutrophil recruitment in insulin resistance and diabetes-related periodontitis in male mice.
Diabetes. 2023 Apr 14:db221014. doi: 10.2337/db22-1014.
PubMed Abstract available

SLOAN G, Anton A, Caunt S, Wilkinson I, et al
Higher sensory cortical energy metabolism in Painful-Diabetic Neuropathy: evidence from a cerebral Magnetic Resonance Spectroscopy study.
Diabetes. 2023 Apr 14:db230051. doi: 10.2337/db23-0051.
PubMed Abstract available

BADIAN RA, Ekman L, Pripp AH, Utheim TP, et al
Comparison of novel wide-field in vivo corneal confocal microscopy with skin biopsy for assessing peripheral neuropathy in type 2 diabetes mellitus.
Diabetes. 2023 Apr 14:db220863. doi: 10.2337/db22-0863.
PubMed Abstract available

SHEN X, Zhang Y, Ji X, Li B, et al
Erratum. Long Noncoding RNA lncRHL Regulates Hepatic VLDL Secretion by Modulating hnRNPU/BMAL1/MTTP Axis. Diabetes 2022;71:1915-1928.
Diabetes. 2023 Apr 3:db23er06. doi: 10.2337.
PubMed Abstract available

MASTRACCI TL, Apte M, Amundadottir LT, Alvarsson A, et al
Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings.
Diabetes. 2023;72:433-448.
PubMed Abstract available

A Special Thanks to the Reviewers of Diabetes.
Diabetes. 2023;72:431-432.
PubMed

March 2023

VIDMAR AP, Durazo-Arvizu R, Weigensberg MJ, Alderete TL, et al
Rapid Decline in Beta-Cell Function and Increasing Adiposity is Associated with Conversion to Type 2 Diabetes in at Risk Latino Youth.
Diabetes. 2023 Mar 27:db221034. doi: 10.2337/db22-1034.
PubMed Abstract available

REN Q, Zhang P, Pang W, Ma Y, et al
A comparison of daily glucose fluctuation among GCK-MODY and type 2 diabetes using continuous glucose monitoring technology.
Diabetes. 2023 Mar 20:db220566. doi: 10.2337/db22-0566.
PubMed Abstract available

PHAM VM, Komirishetty P, Areti A, Poitras T, et al
Combined PTEN knockdown and local insulin in chronic experimental diabetic neuropathy.
Diabetes. 2023 Mar 17:db220743. doi: 10.2337/db22-0743.
PubMed Abstract available

MONICKARAJ F, Acosta G, Cabrera AP, Das A, et al
Transcriptomic Profiling reveals Chemokine CXCL1 as a mediator for Neutrophil Recruitment associated with Blood-Retinal Barrier Alteration in Diabetic Retinopathy.
Diabetes. 2023 Mar 17:db220619. doi: 10.2337/db22-0619.
PubMed Abstract available

XIE L, Lu W, Zhang Y, Deng L, et al
Glucose-activated switch regulating insulin analogue secretion enables long-term precise glucose control in type 1 diabetes mice.
Diabetes. 2023 Mar 13:db220860. doi: 10.2337/db22-0860.
PubMed Abstract available

LIU Z
Cardiac Microvascular Dysfunction and Cardiomyopathy in Diabetes: Is Ferroptosis a Therapeutic Target?
Diabetes. 2023;72:313-315.
PubMed

WAGNER R, Heni M, Kantartzis K, Sandforth A, et al
Lower Hepatic Fat Is Associated With Improved Insulin Secretion in a High-Risk Prediabetes Subphenotype During Lifestyle Intervention.
Diabetes. 2023;72:362-366.
PubMed Abstract available

February 2023

WEI T, Cui X, Jiang Y, Wang K, et al
Glucagon Acting at the GLP-1 Receptor Contributes to beta-Cell Regeneration Induced by Glucagon Receptor Antagonism in Diabetic Mice.
Diabetes. 2023 Feb 24:db220784. doi: 10.2337/db22-0784.
PubMed Abstract available

DIONYSOPOULOU S, Wikstrom P, Bucolo C, Romano GL, et al
Topically administered NOX4 inhibitor, GLX7013114, is efficacious in treating the early pathological events of diabetic retinopathy.
Diabetes. 2023 Feb 23:db220515. doi: 10.2337/db22-0515.
PubMed Abstract available

ZHOU Y, Liu L, Jin B, Wu Y, et al
Metrnl alleviates lipid accumulation by modulating mitochondrial homeostasis in diabetic nephropathy.
Diabetes. 2023 Feb 22:db220680. doi: 10.2337/db22-0680.
PubMed Abstract available

CRONJE HT, Mi MY, Austin TR, Biggs ML, et al
Plasma proteomic risk markers of incident type 2 diabetes reflect physiologically distinct components of glucose-insulin homeostasis.
Diabetes. 2023 Feb 7:db220628. doi: 10.2337/db22-0628.
PubMed Abstract available

REMEDI MS, Nichols CG
Glucokinase Inhibition: A Novel Treatment for Diabetes?
Diabetes. 2023;72:170-174.
PubMed Abstract available

GARFIELD V, Salzmann A, Burgess S, Chaturvedi N, et al
A Guide for Selection of Genetic Instruments in Mendelian Randomization Studies of Type 2 Diabetes and HbA1c: Toward an Integrated Approach.
Diabetes. 2023;72:175-183.
PubMed Abstract available

DRYGALSKI K, Lecoutre S, Clement K, Dugail I, et al
Hyaluronan in Adipose Tissue, Metabolic Inflammation, and Diabetes: Innocent Bystander or Guilty Party?
Diabetes. 2023;72:159-169.
PubMed Abstract available

VILORIA K, Nasteska D, Ast J, Hasib A, et al
GC-Globulin/Vitamin D-Binding Protein Is Required for Pancreatic alpha-Cell Adaptation to Metabolic Stress.
Diabetes. 2023;72:275-289.
PubMed Abstract available

January 2023

NJEIM R, Braych K, Ghadieh HE, Azar NS, et al
VEGF-A: A NOVEL MECHANISTIC LINK BETWEEN CYP2C-DERIVED EET AND NOX4 IN DIABETIC KIDNEY DISEASE.
Diabetes. 2023 Jan 20:db220636. doi: 10.2337/db22-0636.
PubMed Abstract available

GHEIBI S, Cataldo LR, Hamilton A, Huang M, et al
Reduced expression level of protein phosphatase, PPM1E, serves to maintain insulin secretion in type 2 diabetes.
Diabetes. 2023 Jan 20:db220472. doi: 10.2337/db22-0472.
PubMed Abstract available

KAWATA S, Kozawa J, Yoneda S, Fujita Y, et al
Inflammatory Cell Infiltration into Islets without PD-L1 Expression is Associated with the Development of Immune Checkpoint Inhibitor-Related Type 1 Diabetes in Genetically Susceptible Patients.
Diabetes. 2023 Jan 19:db220557. doi: 10.2337/db22-0557.
PubMed Abstract available

NGUYEN A, Khafagy R, Gao Y, Meerasa A, et al
Association between obesity and chronic kidney disease: multivariable Mendelian randomization analysis and observational data from a bariatric surgery cohort.
Diabetes. 2023 Jan 19:db220696. doi: 10.2337/db22-0696.
PubMed Abstract available

CHEN ZZ, Gao Y, Keyes MJ, Deng S, et al
Protein Markers of Diabetes Discovered in an African American Cohort.
Diabetes. 2023 Jan 11:db220710. doi: 10.2337/db22-0710.
PubMed Abstract available

REGUE L, Wang W, Ji F, Avruch J, et al
Human T2D-Associated Gene IMP2/IGF2BP2 Promotes the Commitment of Mesenchymal Stem Cells Into Adipogenic Lineage.
Diabetes. 2023;72:33-44.
PubMed Abstract available

BARANOVA A, Song Y, Cao H, Zhang F, et al
Causal Associations Between Basal Metabolic Rate and COVID-19.
Diabetes. 2023;72:149-154.
PubMed Abstract available

VIVOLI A, Ghislain J, Filali-Mouhim A, Angeles ZE, et al
Single-Cell RNA Sequencing Reveals a Role for Reactive Oxygen Species and Peroxiredoxins in Fatty Acid-Induced Rat beta-Cell Proliferation.
Diabetes. 2023;72:45-58.
PubMed Abstract available

December 2022

KUMAR J, Mohammad G, Alka K, Kowluru RA, et al
Mitochondrial Genome-Encoded Long Noncoding RNA and Mitochondrial Stability in Diabetic Retinopathy.
Diabetes. 2022 Dec 23:db220744. doi: 10.2337/db22-0744.
PubMed Abstract available

LI JH, Perry JA, Jablonski KA, Srinivasan S, et al
Identification of Genetic Variation Influencing Metformin Response in a Multi-Ancestry Genome-Wide Association Study in the Diabetes Prevention Program (DPP).
Diabetes. 2022 Dec 16:db220702. doi: 10.2337/db22-0702.
PubMed Abstract available

PATRA D, Roy S, Arora L, Kabeer SW, et al
miR-210-3p promotes obesity-induced adipose tissue inflammation and insulin resistance by targeting SOCS1 mediated NF-kappaB pathway.
Diabetes. 2022 Dec 5:db220284. doi: 10.2337/db22-0284.
PubMed Abstract available

DODSON M, Shakya A, Anandhan A, Chen J, et al
NRF2 and Diabetes: The Good, the Bad, and the Complex.
Diabetes. 2022;71:2463-2476.
PubMed Abstract available

PETSIOU A, Vartholomatos G, Tsatsoulis A, Papadopoulos GK, et al
Comment on Liu et al. Immune and Metabolic Effects of Antigen-Specific Immunotherapy Using Multiple beta-Cell Peptides in Type 1 Diabetes. Diabetes 2022;71:722-732.
Diabetes. 2022;71:e20-e21.
PubMed

MISRA S, DiMeglio LA
COVID-19 and Incident Type 1 Diabetes: Deciphering the Associations.
Diabetes. 2022;71:2480-2482.
PubMed

PIETROPAOLO M, Hotez P, Giannoukakis N
Response to Comment on Pietropaolo et al. Incidence of an Insulin-Requiring Hyperglycemic Syndrome in SARS-CoV-2- Infected Young Individuals: Is It Type 1 Diabetes? Diabetes 2022;71:2656-2663.
Diabetes. 2022;71:e19.
PubMed

HSU CK, Lai CC
Comment on Pietropaolo et al. Incidence of an Insulin-Requiring Hyperglycemic Syndrome in SARS-CoV-2-Infected Young Individuals: Is It Type 1 Diabetes? Diabetes 2022;71:2656-2663.
Diabetes. 2022;71:e18.
PubMed

SYREENI A, Dahlstrom EH, Hagg-Holmberg S, Forsblom C, et al
Haptoglobin Genotype Does Not Confer a Risk of Stroke in Type 1 Diabetes.
Diabetes. 2022;71:2728-2738.
PubMed Abstract available

MILLER WP, Sha CM, Sunilkumar S, Toro AL, et al
Activation of Disulfide Redox Switch in REDD1 Promotes Oxidative Stress Under Hyperglycemic Conditions.
Diabetes. 2022;71:2764-2776.
PubMed Abstract available

GOU W, Hua W, Swaby L, Cui W, et al
Stem Cell Therapy Improves Human Islet Graft Survival in Mice via Regulation of Macrophages.
Diabetes. 2022;71:2642-2655.
PubMed Abstract available

November 2022

ELABI OF, Karampatsi D, Vercalsteren E, Lietzau G, et al
DPP-4 Inhibitor and Sulfonylurea Differentially Reverse Type 2 Diabetes-Induced Blood-Brain Barrier Leakage and Normalise Capillary Pericyte Coverage.
Diabetes. 2022 Nov 30:db220674. doi: 10.2337/db22-0674.
PubMed Abstract available

GUO Z, Kasinathan D, Merriman C, Nakayama M, et al
A Cell-Surface Autoantibody Targets Zinc Transporter-8 (ZnT8) for in vivo beta-Cell Imaging and Islet-Specific Therapies.
Diabetes. 2022 Nov 30:db220477. doi: 10.2337/db22-0477.
PubMed Abstract available

TEO CHY, Lin MT, Lee IXY, Koh SK, et al
Oral Peroxisome Proliferator-Activated Receptor-Alpha (PPAR)-alpha Agonist Enhances Corneal Nerve Regeneration in Patients with Type II Diabetes Mellitus.
Diabetes. 2022 Nov 29:db220611. doi: 10.2337/db22-0611.
PubMed Abstract available

YAO T, Yan H, Zhu X, Zhang Q, et al
Erratum. Obese Skeletal Muscle-Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome. Diabetes 2022;71:2256-2271.
Diabetes. 2022 Nov 21:db23er02a. doi: 10.2337.
PubMed Abstract available

CHEN Y, Li S, Yin M, Li Y, et al
Isorhapontigenin Attenuates Cardiac Microvascular Injury in Diabetes Mellitus via the Inhibition of Mitochondrial-Derived Ferroptosis Through PRDX2-MFN2-ACSL4 Pathways.
Diabetes. 2022 Nov 11. pii: 147892. doi: 10.2337/db22-0553.
PubMed Abstract available

YADAV Y, Romeres D, Cobelli C, Dalla Man C, et al
Impaired Diurnal Pattern of Meal Tolerance and Insulin Sensitivity in Type 2 Diabetes: Implications for Therapy.
Diabetes. 2022 Nov 8. pii: 147856. doi: 10.2337/db22-0238.
PubMed Abstract available

DERR AG, Arowosegbe A, Satish B, Redick SD, et al
An Early Islet Transcriptional Signature is Associated with Local Inflammation in Autoimmune Diabetes.
Diabetes. 2022 Nov 8. pii: 147854. doi: 10.2337/db22-0521.
PubMed Abstract available

LIU J, Nair V, Zhao YY, Chang DY, et al
Multi-Scalar Data Integration Links Glomerular Angiopoietin-Tie Signaling Pathway Activation With Progression of Diabetic Kidney Disease.
Diabetes. 2022 Nov 4. pii: 147552. doi: 10.2337/db22-0169.
PubMed Abstract available

MOOSHAGE CM, Schimpfle L, Kender Z, Szendroedi J, et al
Diametrical Effects of Glucose Levels on Microvascular Permeability of Peripheral Nerves in Type 2 Diabetes Patients With and Without Diabetic Neuropathy.
Diabetes. 2022 Nov 3. pii: 147851. doi: 10.2337/db22-0548.
PubMed Abstract available

TANG X, Wang J, Abboud HE, Chen Y, et al
Sustained Upregulation of Endothelial Nox4 Mediates Retinal Vascular Pathology in Type 1 Diabetes.
Diabetes. 2022 Nov 2. pii: 147850. doi: 10.2337/db22-0194.
PubMed Abstract available

VAN WALREE ES, Jansen IE, Bell NY, Savage JE, et al
Disentangling Genetic Risks for Metabolic Syndrome.
Diabetes. 2022;71:2447-2457.
PubMed Abstract available

CUI J, Ramesh G, Wu M, Jensen ET, et al
Butyrate-Producing Bacteria and Insulin Homeostasis: The Microbiome and Insulin Longitudinal Evaluation Study (MILES).
Diabetes. 2022;71:2438-2446.
PubMed Abstract available

NG XW, Chung YH, Asadi F, Kong C, et al
RhoA as a Signaling Hub Controlling Glucagon Secretion From Pancreatic alpha-Cells.
Diabetes. 2022;71:2384-2394.
PubMed Abstract available

DOGRA S, Das D, Maity SK, Paul A, et al
Liver-Derived S100A6 Propels beta-Cell Dysfunction in NAFLD.
Diabetes. 2022;71:2284-2296.
PubMed Abstract available

October 2022

SRINIVASAN S, Chen L, Todd J, Divers J, et al
Erratum. The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium. Diabetes 2021;70:996-1005.
Diabetes. 2022 Oct 29. pii: 139086. doi: 10.2337.
PubMed

CHOW E, Wang K, Lim CK, Tsoi ST, et al
Dorzagliatin, a Dual-Acting Glucokinase Activator, Increases Insulin Secretion and Glucose Sensitivity in Glucokinase-Maturity-Onset Diabetes of the Young (GCK-MODY) and Recent-Onset Type 2 Diabetes.
Diabetes. 2022 Oct 28. pii: 147779. doi: 10.2337/db22-0708.
PubMed Abstract available

SUN J, Guan X, Niu C, Chen P, et al
FGF13-sensitive alteration of Parkin safeguards mitochondrial homeostasis in endothelium of diabetic nephropathy.
Diabetes. 2022 Oct 18. pii: 147770. doi: 10.2337/db22-0231.
PubMed Abstract available

TABATABAEI DAKHILI SA, Greenwell AA, Yang K, Farraj RA, et al
The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase.
Diabetes. 2022 Oct 18. pii: 147773. doi: 10.2337/db22-0221.
PubMed Abstract available

ZHU Y, Hedderson MM, Calafat AM, Alexeeff SE, et al
Urinary Phenols in Early to Mid-Pregnancy and Risk of Gestational Diabetes: A Longitudinal Study in a Multiracial Cohort.
Diabetes. 2022 Oct 13. pii: 147711. doi: 10.2337/db22-0028.
PubMed Abstract available

YAMAGUCHI M, Nakao S, Wada I, Matoba T, et al
Identifying Hyperreflective Foci in Diabetic Retinopathy via VEGF-induced Local Self-Renewal of CX3CR1+ Vitreous Resident Macrophages.
Diabetes. 2022 Oct 6. pii: 147604. doi: 10.2337/db21-0247.
PubMed Abstract available

GUYER P, Arribas-Layton D, Manganaro A, Speake C, et al
Recognition of mRNA Splice Variant and Secretory Granule Epitopes by CD4+ T Cells in Type 1 Diabetes.
Diabetes. 2022 Oct 6. pii: 147715. doi: 10.2337/db22-0191.
PubMed Abstract available

CORKEY BE, Kilpatrick LE, Evans-Molina C
Hypothesis: Induction of Autoimmunity in Type 1 Diabetes-A Lipid Focus.
Diabetes. 2022;71:2067-2074.
PubMed Abstract available

SKUDDER-HILL L, Petrov MS
Response to Comment on Skudder-Hill et al. Fat Distribution Within the Pancreas According to Diabetes Status and Insulin Traits. Diabetes 2022;71:1182-1192.
Diabetes. 2022;71:e16-e17.
PubMed

YANG J, Chen Y
Comment on Skudder-Hill et al. Fat Distribution Within the Pancreas According to Diabetes Status and Insulin Traits. Diabetes 2022;71:1182-1192.
Diabetes. 2022;71:e15.
PubMed

September 2022

HONG X, Wu Z, Cao W, Lv J, et al
Longitudinal Association of DNA Methylation with Type 2 Diabetes and Glycemic Traits: A 5-year Cross-Lagged Twin Study.
Diabetes. 2022 Sep 28. pii: 147688. doi: 10.2337/db22-0513.
PubMed Abstract available

RAMMS B, Pollow DP, Zhu H, Nora C, et al
Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity.
Diabetes. 2022 Sep 26. pii: 147565. doi: 10.2337/db21-1131.
PubMed Abstract available

ZURONG Y, Yuandong LI, Xiankui T, Fuhao MO, et al
Morphological and Mechanical Properties of Lower Limb Muscles in Type 2 Diabetes: A New Potential Imaging Indicator for Monitoring the Progress of DPN.
Diabetes. 2022 Sep 20. pii: 147616. doi: 10.2337/db22-0009.
PubMed Abstract available

ROOT KM, Akhaphong B, Cedars MA, Molin AM, et al
Critical Role for Macrophages in the Developmental Programming of Pancreatic beta-cell Area in Offspring of Gestational Hypertension.
Diabetes. 2022 Sep 20. pii: 147567. doi: 10.2337/db22-0404.
PubMed Abstract available

SHARMA A, Lee-Odegard S, Qvigstad E, Sommer C, et al
Beta Cell Function, Hepatic Insulin Clearance, and Insulin Sensitivity in South Asian and Nordic Women after Gestational Diabetes Mellitus.
Diabetes. 2022 Sep 16. pii: 147612. doi: 10.2337/db22-0622.
PubMed Abstract available

KWON BC, Achenbach P, Anand V, Frohnert BI, et al
Islet Autoantibody Levels Differentiate Progression Trajectories in Individuals with Presymptomatic Type 1 Diabetes.
Diabetes. 2022 Sep 16. pii: 147551. doi: 10.2337/db22-0360.
PubMed Abstract available

SHARMA A, Misra-Hebert AD, Mariam A, Milinovich A, et al
Impacts of COVID-19 on Glycemia and Risk of Diabetic Ketoacidosis.
Diabetes. 2022 Sep 15. pii: 147590. doi: 10.2337/db22-0264.
PubMed Abstract available

HOMMER N, Kallab M, Schlatter A, Howorka K, et al
Retinal Oxygen Metabolism in Patients with Type II Diabetes and Different Stages of Diabetic Retinopathy.
Diabetes. 2022 Sep 15. pii: 147603. doi: 10.2337/db22-0219.
PubMed Abstract available

CHANDRASEKARAN S, Melhorn S, Olerich KL, Angelo B, et al
Exposure to Gestational Diabetes Mellitus Prior to 26 Weeks is Related to The Presence of Mediobasal Hypothalamic Gliosis in Children.
Diabetes. 2022 Sep 12. pii: 147591. doi: 10.2337/db22-0448.
PubMed Abstract available

ZHENG F, Ma L, Li X, Gao R, et al
Neutrophil Extracellular Traps Induce Glomerular Endothelial Cell Dysfunction and Pyroptosis in Diabetic Kidney Disease.
Diabetes. 2022 Sep 12. pii: 147589. doi: 10.2337/db22-0153.
PubMed Abstract available

TSOI KY, Zhu Y, Wu J, Sun Q, et al
Plasma Phospholipids Monounsaturated Fatty Acids and Gestational Diabetes Mellitus: a Longitudinal Study in the NICHD Fetal Growth Studies-Singleton Cohort.
Diabetes. 2022 Sep 12. pii: 147570. doi: 10.2337/db22-0241.
PubMed Abstract available

GUO Y, Bian J, Chen A, Wang F, et al
Incidence Trends of New-Onset Diabetes in Children and Adolescents Before and During the COVID-19 Pandemic: Findings from Florida.
Diabetes. 2022 Sep 12. pii: 147562. doi: 10.2337/db22-0549.
PubMed Abstract available

GOSAK M, Yan-Do R, Lin H, MacDonald PE, et al
Ca2+ Oscillations, Waves, and Networks in Islets from Human Donors With and Without Type 2 Diabetes.
Diabetes. 2022 Sep 6. pii: 147556. doi: 10.2337/db22-0004.
PubMed Abstract available

ANG SF, Lim SC
Comment on Colclough et al. and Saint-Martin et al. Syndromic Monogenic Diabetes Genes Should Be Tested in Patients With a Clinical Suspicion of Maturity-Onset Diabetes of the Young. Diabetes 2022;71:530-537, and Gene Panel Sequencing of Patients With
Diabetes. 2022;71:e9-e10.
PubMed

SOOKAROMDEE P, Wiwanitkit V
Comment on D'Addio et al. Immunogenicity and Safety of SARS-CoV-2 mRNA Vaccines in a Cohort of Patients With Type 1 Diabetes. Diabetes 2022;71:1800-1806.
Diabetes. 2022;71:e13.
PubMed

D'ADDIO F, Fiorina P
Response to Comment on D'Addio et al. Immunogenicity and Safety of SARS-CoV-2 mRNA Vaccines in a Cohort of Patients With Type 1 Diabetes. Diabetes 2022;71:1800-1806.
Diabetes. 2022;71:e14.
PubMed

COLCLOUGH K, Patel K
Response to Comment on Colclough et al. and Saint-Martin et al. Syndromic Monogenic Diabetes Genes Should Be Tested in Patients With a Clinical Suspicion of Maturity-Onset Diabetes of the Young. Diabetes 2022;71:530-537, and Gene Panel Sequencing of P
Diabetes. 2022;71:e11-e12.
PubMed

SCHREYER E, Obringer C, Messaddeq N, Kieffer B, et al
PATAS, a First-in-Class Therapeutic Peptide Biologic, Improves Whole-Body Insulin Resistance and Associated Comorbidities In Vivo.
Diabetes. 2022;71:2034-2047.
PubMed Abstract available

YE RZ, Montastier E, Noll C, Frisch F, et al
Total Postprandial Hepatic Nonesterified and Dietary Fatty Acid Uptake Is Increased and Insufficiently Curbed by Adipose Tissue Fatty Acid Trapping in Prediabetes With Overweight.
Diabetes. 2022;71:1891-1901.
PubMed Abstract available

NGUYEN A, Khafagy R, Meerasa A, Roshandel D, et al
Insulin Response to Oral Glucose and Cardiometabolic Disease: A Mendelian Randomization Study to Assess Potential Causality.
Diabetes. 2022;71:1880-1890.
PubMed Abstract available

MEIJNIKMAN AS, van Olden CC, Aydin O, Herrema H, et al
Hyperinsulinemia Is Highly Associated With Markers of Hepatocytic Senescence in Two Independent Cohorts.
Diabetes. 2022;71:1929-1936.
PubMed Abstract available

PERRY RJ
Regulation of Hepatic Lipid and Glucose Metabolism by INSP3R1.
Diabetes. 2022;71:1834-1841.
PubMed Abstract available

RICHTER MM, Galsgaard KD, Elmelund E, Knop FK, et al
The Liver-alpha-Cell Axis in Health and in Disease.
Diabetes. 2022;71:1852-1861.
PubMed Abstract available

August 2022

CRAWFORD SA, Wiles TA, Wenzlau JM, Powell RL, et al
Cathepsin D Drives the Formation of Hybrid Insulin Peptides Relevant to the Pathogenesis of Type 1 Diabetes.
Diabetes. 2022 Aug 30. pii: 147526. doi: 10.2337/db22-0303.
PubMed Abstract available

XU F, Othman B, Lim J, Batres A, et al
Erratum. Foxo1 Inhibits Diabetic Mucosal Wound Healing but Enhances Healing of Normoglycemic Wounds. Diabetes 2015;64:243-256.
Diabetes. 2022 Aug 30. pii: 147527. doi: 10.2337.
PubMed Abstract available

GUSTAFSON B, Nerstedt A, Spinelli R, Beguinot F, et al
Type 2 Diabetes, Independent of Obesity and Age, is Characterized by Senescent and Dysfunctional Mature Human Adipose Cells.
Diabetes. 2022 Aug 25. pii: 147523. doi: 10.2337/db22-0003.
PubMed Abstract available

CHEN ZZ, Pacheco JA, Gao Y, Deng S, et al
Nontargeted and Targeted Metabolomic Profiling Reveals Novel Metabolite Biomarkers of Incident Diabetes in African Americans.
Diabetes. 2022 Aug 23. pii: 147472. doi: 10.2337/db22-0033.
PubMed Abstract available

SUNILKUMAR S, Yerlikaya EI, Toro AL, Miller WP, et al
REDD1 Ablation Attenuates the Development of Renal Complications in Diabetic Mice.
Diabetes. 2022 Aug 19. pii: 147464. doi: 10.2337/db22-0402.
PubMed Abstract available

YE Z, Wang S, Huang X, Chen P, et al
Plasma exosomal microRNAs Associated with Metabolism as Early Predictor of Gestational Diabetes Mellitus.
Diabetes. 2022 Aug 4. pii: 147381. doi: 10.2337/db21-0909.
PubMed Abstract available

MALLONE R, Halliez C, Rui J, Herold KC, et al
The beta-Cell in Type 1 Diabetes Pathogenesis: A Victim of Circumstances or an Instigator of Tragic Events?
Diabetes. 2022;71:1603-1610.
PubMed Abstract available

CHEN L
Metabolomic Markers in Early Pregnancy for Gestational Diabetes Mellitus.
Diabetes. 2022;71:1620-1622.
PubMed

ZHU Z, Wang K, Hao X, Chen L, et al
Causal Graph Among Serum Lipids and Glycemic Traits: A Mendelian Randomization Study.
Diabetes. 2022;71:1818-1826.
PubMed Abstract available

WRUBLEWSKY S, Speer T, Nalbach L, Boewe AS, et al
Targeting Pancreatic Islet NLRP3 Improves Islet Graft Revascularization.
Diabetes. 2022;71:1706-1720.
PubMed Abstract available

NAKAFUSA Y, Nitta N, Ishii K, Shirasu N, et al
Acceptance of Murine Islet Allografts Without Immunosuppression in Inguinal Subcutaneous White Adipose Tissue Pretreated With bFGF.
Diabetes. 2022;71:1721-1734.
PubMed Abstract available

MARTINS PECANHA FL, Jaafar R, Werneck-de-Castro JP, Apostolopolou CC, et al
The Transcription Factor YY1 Is Essential for Normal DNA Repair and Cell Cycle in Human and Mouse beta-Cells.
Diabetes. 2022;71:1694-1705.
PubMed Abstract available

July 2022

CHEN Z, Haus JM, Chen L, Jiang Y, et al
Inhibition of CCL28/CCR10-mediated eNOS Downregulation Improves Skin Wound Healing in the Obesity-induced Mouse Model of Type 2 Diabetes.
Diabetes. 2022 Jul 28. pii: 147325. doi: 10.2337/db21-1108.
PubMed Abstract available

CHEN H, Wu A, Zeidel ML, Yu W, et al
Smooth Muscle Insulin Receptor Deletion Causes Voiding Dysfunction: A Mechanism for Diabetic Bladder Dysfunction.
Diabetes. 2022 Jul 25. pii: 147284. doi: 10.2337/db22-0233.
PubMed Abstract available

VERHULST CEM, van Heck JIP, Fabricius TW, Stienstra R, et al
Sustained Pro-Inflammatory Effects of Hypoglycemia in People with Type 2 Diabetes and in People Without Diabetes.
Diabetes. 2022 Jul 18. pii: 147247. doi: 10.2337/db22-0246.
PubMed Abstract available

KONG Q, Zou J, Zhang Z, Pan R, et al
BAF60a Deficiency in Macrophage Promotes Diet-Induced Obesity and Metabolic Inflammation.
Diabetes. 2022 Jul 13. pii: 147222. doi: 10.2337/db22-0114.
PubMed Abstract available

BEHERA J, Ison J, Voor MJ, Tyagi N, et al
Exercise-Linked Skeletal Irisin Ameliorates Diabetes-Associated Osteoporosis by Inhibiting the Oxidative Damage-Dependent miR-150-FNDC5/Pyroptosis Axis.
Diabetes. 2022 Jul 8. pii: 147211. doi: 10.2337/db21-0573.
PubMed Abstract available

DARDENNE C, Salon M, Authier H, Meunier E, et al
Topical Aspirin Administration Improves Cutaneous Wound Healing in Diabetic Mice Through a Phenotypic Switch of Wound Macrophages Toward an Anti-Inflammatory and Pro-Resolutive Profile Characterized by LXA4 Release.
Diabetes. 2022 Jul 7. pii: 147206. doi: 10.2337/db20-1245.
PubMed Abstract available

STENSEN S, Gasbjerg LS, Rosenkilde MM, Vilsboll T, et al
Endogenous Glucose-Dependent Insulinotropic Polypeptide Contributes to Sitagliptin-Mediated Improvement in Beta Cell Function in Patients with Type 2 Diabetes.
Diabetes. 2022 Jul 7. pii: 147207. doi: 10.2337/db22-0059.
PubMed Abstract available

GRANDE EM, Raka F, Hoffman S, Adeli K, et al
GLP-2 Regulation of Dietary Fat Absorption and Intestinal Chylomicron Production via Neuronal Nitric Oxide Synthase (nNOS) Signaling.
Diabetes. 2022;71:1388-1399.
PubMed Abstract available

CHEUNG R, Pizza G, Chabosseau P, Rolando D, et al
Glucose-Dependent miR-125b Is a Negative Regulator of beta-Cell Function.
Diabetes. 2022;71:1525-1545.
PubMed Abstract available

DU YQ, Sha XY, Cheng J, Wang J, et al
Endogenous Lipid-GPR120 Signaling Modulates Pancreatic Islet Homeostasis to Different Extents.
Diabetes. 2022;71:1454-1471.
PubMed Abstract available

June 2022

CHEN M, Hu R, Cavinato C, Zhuang ZW, et al
Fibronectin-integrin alpha5 signaling in vascular complications of type 1 diabetes.
Diabetes. 2022 Jun 30. pii: 147154. doi: 10.2337/db21-0958.
PubMed Abstract available

GOTTMANN P, Speckmann T, Stadion M, Zuljan E, et al
Heterogeneous Development of beta-Cell Populations In Diabetes-Resistant and -Susceptible Mice.
Diabetes. 2022 Jun 30. pii: 147150. doi: 10.2337/db21-1030.
PubMed Abstract available

ITO Y, Sun R, Yagimuma H, Taki K, et al
Protein Tyrosine Phosphatase 1B Deficiency Improves Glucose Homeostasis in Insulin-Dependent Diabetes Mellitus Treated with Leptin.
Diabetes. 2022 Jun 24. pii: 147141. doi: 10.2337/db21-0953.
PubMed Abstract available

MEI-LING Y, Sean E C, Renelle G, TuKiet T L, et al
Carbonyl Post-Translational Modification Associated with Early Onset Type 1 Diabetes Autoimmunity.
Diabetes. 2022 Jun 22. pii: 147120. doi: 10.2337/db21-0989.
PubMed Abstract available

YAMAZAKI H, Tauchi S, Machann J, Haueise T, et al
Fat-distribution Patterns and Future Type-2 Diabetes.
Diabetes. 2022 Jun 20. pii: 147108. doi: 10.2337/db22-0315.
PubMed Abstract available

CARRY PM, Waugh K, Vanderlinden LA, Johnson RK, et al
Changes in the Co-Expression of Innate Immunity Genes During Persistent Islet Autoimmunity are Associated with Progression of Islet Autoimmunity: The Diabetes Autoimmunity Study in the Young (DAISY).
Diabetes. 2022 Jun 20. pii: 147107. doi: 10.2337/db21-1111.
PubMed Abstract available

LEUNG SS, Borg DJ, McCarthy DA, Boursalian TE, et al
Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells.
Diabetes. 2022 Jun 17. pii: 147090. doi: 10.2337/db22-0177.
PubMed Abstract available

JIA C, Wang R, Long T, Xu Y, et al
NRF2 Genetic Polymorphism Modifies the Association of Plasma Selenium Levels With Incident Coronary Heart Disease among Type 2 Diabetes Individuals.
Diabetes. 2022 Jun 17. pii: 147088. doi: 10.2337/db21-1124.
PubMed Abstract available

MACDONALD MJ, Ansari IH, Riedemann AS, Stoker SW, et al
A Novel Intron-Encoded Neuropilin-1 Isoform in Pancreatic Islets Associated With Very Young Age of Onset of Type 1 Diabetes.
Diabetes. 2022 Jun 17. pii: 147085. doi: 10.2337/db21-1070.
PubMed Abstract available

SUN W, Nie T, Li K, Wu W, et al
Erratum. Hepatic CPT1A Facilitates Liver-Adipose Cross Talk via Induction of FGF21 in Mice. Diabetes 2022;71:31-42.
Diabetes. 2022 Jun 7. pii: 147064. doi: 10.2337.
PubMed Abstract available

JONES AG, Eichmann M
T-Cell Autoreactivity in Type 2 Diabetes: Benign or Pathogenic, Smoke or Fire?
Diabetes. 2022;71:1167-1169.
PubMed

May 2022

SIERRA-SILVESTRE E, Andrade RJ, Schroeter AC, Bisset L, et al
Diabetic Neuropathy in Hands: An Endemic Complication Waiting to Unfold?
Diabetes. 2022 May 27. pii: 147000. doi: 10.2337/db21-1147.
PubMed Abstract available

LIN Y, Perovanovic J, Kong Y, Igyarto BZ, et al
Antibody-Mediated Targeting of a Hybrid-Insulin-Peptide Towards Neonatal Thymic Langerin+ Cells Enhances T Cell Central Tolerance and Delays Autoimmune Diabetes.
Diabetes. 2022 May 27. pii: 147050. doi: 10.2337/db21-1069.
PubMed Abstract available

CHEN H, Wang M, Xia L, Dong J, et al
New Evidence of Central Nervous System Damage in Diabetes Mellitus: Impairment of Fine Visual Discrimination.
Diabetes. 2022 May 25. pii: 147009. doi: 10.2337/db21-0715.
PubMed Abstract available

XU R, Fu J, Hu Y, Yang X, et al
Roflumilast-Mediated Phosphodiesterase 4D Inhibition Reverses Diabetes-Associated Cardiac Dysfunction and Remodeling: Effects Beyond Glucose Lowering.
Diabetes. 2022 May 20. pii: 146983. doi: 10.2337/db21-0898.
PubMed Abstract available

BAKER NL, Hammad SM, Hunt KJ, Semler A, et al
Plasma ApoM levels and Progression to Kidney Dysfunction in Type 1 Diabetics.
Diabetes. 2022 May 12. pii: 146945. doi: 10.2337/db21-0920.
PubMed Abstract available

D'ADDIO F, Sabiu G, Usuelli V, Assi E, et al
Immunogenicity and safety of SARS-CoV-2 mRNA vaccines in a cohort of patients with type 1 diabetes.
Diabetes. 2022 May 12. pii: 146944. doi: 10.2337/db22-0053.
PubMed Abstract available

ZHU Y, Barupal DK, Ngo AL, Quesenberry CP, et al
Predictive Metabolomic Markers in Early to Mid-Pregnancy for Gestational Diabetes: A Prospective Test and Validation Study.
Diabetes. 2022 May 9. pii: 146809. doi: 10.2337/db21-1093.
PubMed Abstract available

CARR ALJ, Inshaw JRJ, Flaxman CS, Leete P, et al
Circulating C-Peptide Levels in Living Children and Young People and Pancreatic Beta Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration.
Diabetes. 2022 May 2. pii: 146866. doi: 10.2337/db22-0097.
PubMed Abstract available

YIP L, Alkhataybeh R, Taylor C, Fuhlbrigge R, et al
Identification of Novel Disease-Relevant Genes and Pathways in the Pathogenesis of Type 1 Diabetes: A Potential Defect in Pancreatic Iron Homeostasis.
Diabetes. 2022 May 2. pii: 146861. doi: 10.2337/db21-0948.
PubMed Abstract available

BAUMEL-ALTERZON S, Katz LS, Brill G, Jean-Pierre C, et al
Nrf2 Regulates beta-Cell Mass by Suppressing beta-Cell Death and Promoting beta-Cell Proliferation.
Diabetes. 2022;71:989-1011.
PubMed Abstract available

LARSEN JK, Larsen MR, Birk JB, Steenberg DE, et al
Illumination of the Endogenous Insulin-Regulated TBC1D4 Interactome in Human Skeletal Muscle.
Diabetes. 2022;71:906-920.
PubMed Abstract available

NIU Y, Jiang H, Yin H, Wang F, et al
Hepatokine ERAP1 Disturbs Skeletal Muscle Insulin Sensitivity Via Inhibiting USP33-Mediated ADRB2 Deubiquitination.
Diabetes. 2022;71:921-933.
PubMed Abstract available

JING Y, Kong Y, McGinty J, Blahnik-Fagan G, et al
T-Cell Receptor/HLA Humanized Mice Reveal Reduced Tolerance and Increased Immunogenicity of Posttranslationally Modified GAD65 Epitope.
Diabetes. 2022;71:1012-1022.
PubMed Abstract available

JOKIAHO AJ, Winchester M, Donovan CM
N-Hydroxyethyl-1-Deoxynojirimycin (Miglitol) Restores the Counterregulatory Response to Hypoglycemia Following Antecedent Hypoglycemia.
Diabetes. 2022;71:1063-1072.
PubMed Abstract available

LIU D, Yang KY, Chan VW, Ye W, et al
YY1 Regulates Glucose Homeostasis Through Controlling Insulin Transcription in Pancreatic beta-Cells.
Diabetes. 2022;71:961-977.
PubMed Abstract available

LAVER TW, Wakeling MN, Knox O, Colclough K, et al
Evaluation of Evidence for Pathogenicity Demonstrates That BLK, KLF11, and PAX4 Should Not Be Included in Diagnostic Testing for MODY.
Diabetes. 2022;71:1128-1136.
PubMed Abstract available

April 2022

KIM YY, Jang H, Lee G, Jeon YG, et al
Hepatic GSK3beta-dependent CRY1 Degradation Contributes to Diabetic Hyperglycemia.
Diabetes. 2022 Apr 27. pii: 145076. doi: 10.2337/db21-0649.
PubMed Abstract available

YU P, Guo J, Li J, Shi X, et al
LncRNA-H19 in Fibroblasts Promotes Diabetic Wound Healing.
Diabetes. 2022 Apr 26. pii: 145038. doi: 10.2337/db21-0724.
PubMed Abstract available

LEE S, Xu H, Van Vleck A, Mawla AM, et al
beta-Cell Succinate Dehydrogenase Deficiency Triggers Metabolic Dysfunction and Insulinopenic Diabetes.
Diabetes. 2022 Apr 26. pii: 145039. doi: 10.2337/db21-0834.
PubMed Abstract available

MOON JS, Riopel M, Seo JB, Herrero-Aguayo V, et al
HIF-2alpha Preserves Mitochondrial Activity And Glucose Sensing in Compensating Beta Cells in Obesity.
Diabetes. 2022 Apr 26. pii: 145037. doi: 10.2337/db21-0736.
PubMed Abstract available

DUNNE JL, Maizel JL, Posgai AL, Atkinson MA, et al
Erratum. The Women's Leadership Gap in Diabetes: A Call for Equity and Excellence. Diabetes 2021;70:1623-1633.
Diabetes. 2022 Apr 5. pii: 144981. doi: 10.2337.
PubMed Abstract available

DE BRITO MONTEIRO L, Silveira Prodonoff J, Favero de Aguiar C, Correa-da-Silva F, et al
Circulating Metabolites Associate with and Improve the Prediction of All-Cause Mortality in Type 2 Diabetes.
Diabetes. 2022 Apr 4. pii: 144973. doi: 10.2337/db21-0842.
PubMed Abstract available

SIMS EK, Besser REJ, Dayan C, Geno Rasmussen C, et al
Screening for Type 1 Diabetes in the General Population: A Status Report and Perspective.
Diabetes. 2022;71:610-623.
PubMed Abstract available

ESPINOSA DE YCAZA AE, Sondergaard E, Jensen MD
Response to Comment on Espinosa De Ycaza et al. Adipose Tissue Inflammation Is Not Related to Adipose Insulin Resistance in Humans. Diabetes 2022;71:381-393.
Diabetes. 2022;71:e8-e9.
PubMed

TROUWBORST I, Goossens GH
Comment On Espinosa De Ycaza et al. Adipose Tissue Inflammation Is Not Related to Adipose Insulin Resistance in Humans. Diabetes 2022;71:381-393.
Diabetes. 2022;71:e6-e7.
PubMed

KAHN DE, Bergman BC
Keeping It Local in Metabolic Disease: Adipose Tissue Paracrine Signaling and Insulin Resistance.
Diabetes. 2022;71:599-609.
PubMed Abstract available

CARRASCO M, Wang C, Soviknes AM, Bjorlykke Y, et al
Spatial Environment Affects HNF4A Mutation-Specific Proteome Signatures and Cellular Morphology in hiPSC-Derived beta-Like Cells.
Diabetes. 2022;71:862-869.
PubMed Abstract available

March 2022

SCARALE MG, Mastroianno M, Prehn C, Copetti M, et al
Circulating Metabolites Associate with and Improve the Prediction of All-Cause Mortality in Type 2 Diabetes.
Diabetes. 2022 Mar 31. pii: 144922. doi: 10.2337/db22-0095.
PubMed Abstract available

KULYTE A, Aman A, Strawbridge RJ, Arner P, et al
Genome-wide Association Study Identifies Genetic Loci Associated with Fat Cell Number and Overlap with Genetic Risk Loci For Type 2 Diabetes.
Diabetes. 2022 Mar 23. pii: 144852. doi: 10.2337/db21-0804.
PubMed Abstract available

YAN Z, Fortunato M, Shyr ZA, Clark AL, et al
Genetic Reduction of Glucose Metabolism Preserves Functional beta-cell Mass in KATP-Induced Neonatal Diabetes.
Diabetes. 2022 Mar 16. pii: 144834. doi: 10.2337/db21-0992.
PubMed Abstract available

CHAI JC, Chen GC, Yu B, Xing J, et al
Serum Metabolomics of Incident Diabetes and Glycemic Changes in a Population With High Diabetes Burden: the Hispanic Community Health Study/Study of Latinos.
Diabetes. 2022 Mar 16. pii: 144831. doi: 10.2337/db21-1056.
PubMed Abstract available

PIETROPAOLO M, Hotez P, Giannoukakis N
Incidence of an Insulin-Requiring Hyperglycemic Syndrome in SARS CoV-2-Infected Young Individuals: Is it Type 1 Diabetes?
Diabetes. 2022 Mar 16. pii: 144830. doi: 10.2337/db21-0831.
PubMed Abstract available

CHI H, Yao R, Sun C, Leng B, et al
Blood Neuroexosomal Mitochondrial Proteins Predict Alzheimer's Disease in Diabetes Mellitus.
Diabetes. 2022 Mar 14. pii: 144735. doi: 10.2337/db21-0969.
PubMed Abstract available

MIYASHITA A, Kobayashi M, Ishibashi S, Nagata T, et al
The Role of Long Non-coding RNA MALAT1 in Diabetic Polyneuropathy and the Impact of its Silencing in the Dorsal Root Ganglion by a DNA/RNA Heteroduplex Oligonucleotide.
Diabetes. 2022 Mar 11. pii: 144730. doi: 10.2337/db21-0918.
PubMed Abstract available

JHA JC, Dai A, Garzarella J, Charlton A, et al
Independent of Renox, NOX5 Promotes Renal Inflammation and Fibrosis in Diabetes by Activating ROS-sensitive Pathways.
Diabetes. 2022 Mar 11. pii: 144729. doi: 10.2337/db21-1079.
PubMed Abstract available

GHANBARI F, Yazdanpanah N, Yazdanpanah M, Richards JB, et al
Connecting Genomics and Proteomics to Identify Protein Biomarkers for Adult and Youth-Onset Type 2 Diabetes: A Two-Sample Mendelian Randomization Study.
Diabetes. 2022 Mar 2. pii: 144635. doi: 10.2337/db21-1046.
PubMed Abstract available

SKUDDER-HILL L, Sequeira IR, Cho J, Ko J, et al
Fat Distribution Within the Pancreas According to Diabetes Status and Insulin Traits.
Diabetes. 2022 Mar 2. pii: 144633. doi: 10.2337/db21-0976.
PubMed Abstract available

ZHOU X, Zhu Y, Wang Z, Lin Z, et al
Rate-dependent Depression: A Predictor of the Therapeutic Efficacy in Treating Painful Diabetic Peripheral Neuropathy.
Diabetes. 2022 Mar 2. pii: 144634. doi: 10.2337/db21-0960.
PubMed Abstract available

NICHOLS CG, York NW, Remedi MS
ATP-Sensitive Potassium Channels in Hyperinsulinism and Type 2 Diabetes: Inconvenient Paradox or New Paradigm?
Diabetes. 2022;71:367-375.
PubMed Abstract available

KJOBSTED R, Wojtaszewski JFP
Comment on De Wendt et al. Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1. Diabetes 2021;70:2796-2809.
Diabetes. 2022;71:e3-e4.
PubMed

DI PAOLA R, Marucci A, Trischitta V
The Need to Increase Clinical Skills and Change the Genetic Testing Strategy for Monogenic Diabetes.
Diabetes. 2022;71:379-380.
PubMed

CHADT A, Al-Hasani H
Response to Comment on Wendt et al. Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1. Diabetes 2021;70:2796-2809.
Diabetes. 2022;71:e5.
PubMed

ALLU PKR, Kiranmayi M, Mukherjee SD, Chirasani VR, et al
Functional Gly297Ser Variant of the Physiological Dysglycemic Peptide Pancreastatin Is a Novel Risk Factor for Cardiometabolic Disorders.
Diabetes. 2022;71:538-553.
PubMed Abstract available

February 2022

RUSTAGI Y, Abouhashem AS, Verma P, Verma SS, et al
Endothelial Phospholipase Cgamma2 Improves Outcomes of Diabetic Ischemic Limb Rescue Following VEGF Therapy.
Diabetes. 2022 Feb 22. pii: 144596. doi: 10.2337/db21-0830.
PubMed Abstract available

ZHAO L, Zhang CL, He L, Chen Q, et al
Restoration of Autophagic Flux Improves Endothelial Function in Diabetes Through Lowering Mitochondrial ROS-mediated eNOS Monomerization.
Diabetes. 2022 Feb 18. pii: 144595. doi: 10.2337/db21-0660.
PubMed Abstract available

DING G, Li L, Zhang L, Chopp M, et al
MRI Metrics of Cerebral Endothelial Cell Derived Exosomes for the Treatment of Cognitive Dysfunction Induced in Ageing Rats Subjected to Type-2 Diabetes.
Diabetes. 2022 Feb 17. pii: 144591. doi: 10.2337/db21-0754.
PubMed Abstract available

MILLER WP, Toro AL, Sunilkumar S, Stevens SA, et al
Muller Glial Expression of REDD1 is Required for Retinal Neurodegeneration and Visual Dysfunction in Diabetic Mice.
Diabetes. 2022 Feb 15. pii: 144560. doi: 10.2337/db21-0853.
PubMed Abstract available

LI C, Li L, Yang M, Yang J, et al
PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy.
Diabetes. 2022 Feb 8. pii: 144536. doi: 10.2337/db21-0983.
PubMed Abstract available

KIM J, Jensen A, Ko S, Raghavan S, et al
Systematic Heritability and Heritability Enrichment Analysis for Diabetes Complications in UK Biobank and ACCORD Studies.
Diabetes. 2022 Feb 8. pii: 144534. doi: 10.2337/db21-0839.
PubMed Abstract available

LI YL, Wu JJ, Ma J, Li SS, et al
Alteration of Individual Metabolic Network of Brain Based on Jensen-Shannon Divergence Similarity Estimation in the Elderly with Type 2 Diabetes Mellitus.
Diabetes. 2022 Feb 8. pii: 144535. doi: 10.2337/db21-0600.
PubMed Abstract available

MARINO F, Scalise M, Salerno N, Salerno L, et al
Diabetes-Induced Cellular Senescence and Senescence-Associated Secretory Phenotype Impair Cardiac Regeneration and Function Independently of Age.
Diabetes. 2022 Feb 2. pii: 141061. doi: 10.2337/db21-0536.
PubMed Abstract available

USSHER JR, Greenwell AA, Nguyen MA, Mulvihill EE, et al
Cardiovascular Effects of Incretin-Based Therapies: Integrating Mechanisms With Cardiovascular Outcome Trials.
Diabetes. 2022;71:173-183.
PubMed Abstract available

RIVEROS-MCKAY F, Roberts D, Di Angelantonio E, Yu B, et al
An Expanded Genome-Wide Association Study of Fructosamine Levels Identifies RCN3 as a Replicating Locus and Implicates FCGRT as the Effector Transcript.
Diabetes. 2022;71:359-364.
PubMed Abstract available

LIU R, Pugh GH, Tevonian E, Thompson K, et al
Regulatory T Cells Control Effector T Cell Inflammation in Human Prediabetes.
Diabetes. 2022;71:264-274.
PubMed Abstract available

January 2022

WIGGENHAUSER LM, Metzger L, Bennewitz K, Soleymani S, et al
pdx1 Knockout Leads to a Diabetic Nephropathy-Like Phenotype in Zebrafish and Identifies Phosphatidylethanolamine as Metabolite Promoting Early Diabetic Kidney Damage.
Diabetes. 2022 Jan 31. pii: 141050. doi: 10.2337/db21-0645.
PubMed Abstract available

YANG Q, Hinkle J, Reed JN, Aherrahrou R, et al
Adipocyte-Specific Modulation of KLF14 Expression in Mice Leads to Sex-Dependent Impacts on Adiposity and Lipid Metabolism.
Diabetes. 2022 Jan 26. pii: 140940. doi: 10.2337/db21-0674.
PubMed Abstract available

FAN HM, Mitchell AL, Bellafante E, McIlvride S, et al
Sulfated Progesterone Metabolites That Enhance Insulin Secretion Via Trpm3 are Reduced in Serum From Women with Gestational Diabetes Mellitus.
Diabetes. 2022 Jan 24. pii: 141009. doi: 10.2337/db21-0702.
PubMed Abstract available

PARKER DC, Wan M, Lohman K, Hou L, et al
Monocyte miRNAs are Associated with Type 2 Diabetes.
Diabetes. 2022 Jan 24. pii: 141010. doi: 10.2337/db21-0704.
PubMed Abstract available

LIU YF, Powrie J, Arif S, Yang JHM, et al
Immune and Metabolic Effects of Antigen-Specific Immunotherapy Using Multiple beta-Cell Peptides in Type 1 Diabetes.
Diabetes. 2022 Jan 24. pii: 140961. doi: 10.2337/db21-0728.
PubMed Abstract available

WOLSK E, Jurgens M, Schou M, Ersboll M, et al
A Randomized Controlled Trial of the Hemodynamic Effects of Empagliflozin in Patients with Type 2 Diabetes at High Cardiovascular Risk (the SIMPLE Trial).
Diabetes. 2022 Jan 21. pii: 140950. doi: 10.2337/db21-0721.
PubMed Abstract available

KONIGS V, Pierre S, Schicht M, Welss J, et al
GPR40 Activation Abolishes Diabetes-Induced Painful Neuropathy by Suppressing VEGF-A Expression.
Diabetes. 2022 Jan 21. pii: 140941. doi: 10.2337/db21-0711.
PubMed Abstract available

HU Z, Mao X, Chen M, Wu X, et al
Single-cell transcriptomics reveals novel role of microglia in fibrovascular membrane of proliferative diabetic retinopathy.
Diabetes. 2022 Jan 21. pii: 140944. doi: 10.2337/db21-0551.
PubMed Abstract available

BROOKS-WORRELL B, Hampe CS, Hattery EG, Palomino B, et al
Islet Autoimmunity is Highly Prevalent and Associated With Diminished beta-Cell Function in Patients With Type 2 Diabetes in the Grade Study.
Diabetes. 2022 Jan 21. pii: 140947. doi: 10.2337/db21-0590.
PubMed Abstract available

ELVIRA B, Vandenbempt V, Bauza-Martinez J, Crutzen R, et al
PTPN2 Regulates the Interferon Signaling and Endoplasmic Reticulum Stress Response in Pancreatic beta-Cells in Autoimmune Diabetes.
Diabetes. 2022 Jan 14. pii: 139308. doi: 10.2337/db21-0443.
PubMed Abstract available

LIANG W, Huang L, Ma X, Dong L, et al
Pathogenic Role of Diabetes-induced Overexpression of Kallistatin in Corneal Wound Healing Deficiency through Inhibition of Canonical Wnt Signaling.
Diabetes. 2022 Jan 14. pii: 139310. doi: 10.2337/db21-0740.
PubMed Abstract available

KAVAZOVIC I, Krapic M, Beumer-Chuwonpad A, Polic B, et al
Hyperglycemia and Not Hyperinsulinemia Mediates Diabetes-Induced Memory Cd8 T Cell Dysfunction.
Diabetes. 2022 Jan 14. pii: 139330. doi: 10.2337/db21-0209.
PubMed Abstract available

CHEN X, Li Y, Yuan X, Yuan W, et al
Methazolamide Attenuates the Development of Diabetic Cardiomyopathy by Promoting beta-Catenin Degradation in Type 1 Diabetic Mice.
Diabetes. 2022 Jan 14. pii: 139251. doi: 10.2337/db21-0506.
PubMed Abstract available

JIANG G, Luk AO, Tam CHT, Ozaki R, et al
Clinical Predictors and Long-term Impact of Acute Kidney Injury on Progression of Diabetic Kidney Disease in Chinese Patients with Type 2 Diabetes.
Diabetes. 2022 Jan 14. pii: 139252. doi: 10.2337/db21-0694.
PubMed Abstract available

AN D, Tan B, Yu DY, Balaratnasingam C, et al
Differentiating Microaneurysm Pathophysiology in Diabetic Retinopathy Through Objective Analysis of Capillary Nonperfusion, Inflammation and Pericytes.
Diabetes. 2022 Jan 14. pii: 139305. doi: 10.2337/db21-0737.
PubMed Abstract available

DOLLET L, Kuefner M, Caria E, Rizo-Roca D, et al
Glutamine Regulates Skeletal Muscle Immunometabolism in Type 2 Diabetes.
Diabetes. 2022 Jan 14. pii: 139331. doi: 10.2337/db20-0814.
PubMed Abstract available

GARRANZO-ASENSIO M, Solijs-Fernandez G, Montero-Calle A, Garcija-Martijnez JM, et al
Seroreactivity Against Tyrosine Phosphatase PTPRN Links Type 2 Diabetes and Colorectal Cancer and Identifies a Potential Diagnostic and Therapeutic Target.
Diabetes. 2022 Jan 14. pii: 139253. doi: 10.2337/db20-1206.
PubMed Abstract available

LOCKER KCS, Kachapati K, Wu Y, Bednar KJ, et al
Endosomal Sequestration of TLR4 Antibody Induces Myeloid-Derived Suppressor Cells and Reverses Acute Type 1 Diabetes.
Diabetes. 2022 Jan 14. pii: 139245. doi: 10.2337/db21-0426.
PubMed Abstract available

ALAM M, Arunagiri A, Haataja L, Torres M, et al
Erratum. Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes. Diabetes 2021;70:2580-2594.
Diabetes. 2022 Jan 7. pii: 139220. doi: 10.2337.
PubMed

JAMISON BL, DiLisio JE, Beard KS, Neef T, et al
Tolerogenic Delivery of a Hybrid Insulin Peptide Markedly Prolongs Islet Graft Survival in the Non-Obese Diabetic (NOD) Mouse.
Diabetes. 2022 Jan 7. pii: 139243. doi: 10.2337/db20-1170.
PubMed Abstract available

BEDIAGA NG, Garnham AL, Naselli G, Bandala-Sanchez E, et al
Cytotoxicity-related gene expression and chromatin accessibility define a subset of CD4+ T cells that mark progression to type 1 diabetes.
Diabetes. 2022 Jan 7. pii: 139244. doi: 10.2337/db21-0612.
PubMed Abstract available

TSE G, Liu T, Roever L, Lee S, et al
The Women's Leadership Gap in Diabetes: A Call for Equity and Excellence. Diabetes 2021;70:1623-1633.
Diabetes. 2022;71:e1-e2.
PubMed

December 2021

O'CONNOR MJ, Schroeder P, Huerta-Chagoya A, Cortes-Sanchez P, et al
Recessive Genome-wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes.
Diabetes. 2021 Dec 3. pii: db21-0545. doi: 10.2337/db21-0545.
PubMed Abstract available

BOEDER SC, Gregory JM, Giovannetti ER, Pettus JH, et al
SGLT2 Inhibition Increases Fasting Glucagon but Does Not Restore the Counterregulatory Hormone Response to Hypoglycemia in Participants with Type 1 Diabetes.
Diabetes. 2021 Dec 2. pii: db21-0769. doi: 10.2337/db21-0769.
PubMed Abstract available

PANZER JK, Caicedo A
Targeting the Pancreatic alpha-Cell to Prevent Hypoglycemia in Type 1 Diabetes.
Diabetes. 2021;70:2721-2732.
PubMed Abstract available

GLAVAS MM, Lee AY, Miao I, Yang F, et al
Developmental Timing of High-Fat Diet Exposure Impacts Glucose Homeostasis in Mice in a Sex-Specific Manner.
Diabetes. 2021;70:2771-2784.
PubMed Abstract available

FRITSCHE A, Wagner R, Heni M, Kantartzis K, et al
Different Effects of Lifestyle Intervention in High- and Low-Risk Prediabetes: Results of the Randomized Controlled Prediabetes Lifestyle Intervention Study (PLIS).
Diabetes. 2021;70:2785-2795.
PubMed Abstract available

November 2021

FENG H, Shen H, Robeson MJ, Wu YH, et al
MG53 E3 Ligase-dead Mutant Protects Diabetic Hearts from Acute Ischemic/Reperfusion Injury and Ameliorates Diet-induced Cardiometabolic Damage.
Diabetes. 2021 Nov 29. pii: db21-0322. doi: 10.2337/db21-0322.
PubMed Abstract available

SMITH MJ, Pastor L, Newman JRB, Concannon P, et al
Genetic Control of Splicing at SIRPG Modulates Risk of Type 1 Diabetes.
Diabetes. 2021 Nov 19. pii: db21-0194. doi: 10.2337/db21-0194.
PubMed Abstract available

COLCLOUGH K, Ellard S, Hattersley A, Patel K, et al
Syndromic Monogenic Diabetes Genes Should be Tested in Patients With a Clinical Suspicion of MODY.
Diabetes. 2021 Nov 17. pii: db21-0517. doi: 10.2337/db21-0517.
PubMed Abstract available

OUIDIR M, Zeng X, Chatterjee S, Zhang C, et al
Ancestry-Matched and Cross-Ancestry Genetic Risk Scores of Type 2 Diabetes in Pregnant Women and Fetal Growth - a Study in an Ancestrally Diverse Cohort.
Diabetes. 2021 Nov 17. pii: db21-0655. doi: 10.2337/db21-0655.
PubMed Abstract available

CEFALU WT, Andersen DK, Arreaza-Rubin G, Pin CL, et al
Heterogeneity of Diabetes: beta-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of He
Diabetes. 2021 Nov 15. pii: db21-0777. doi: 10.2337/db21-0777.
PubMed Abstract available

CEFALU WT, Andersen DK, Arreaza-Rubin G, Pin CL, et al
Heterogeneity of Diabetes: beta-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of He
Diabetes. 2021 Nov 13. pii: 139084. doi: 10.2337/db21-0777.
PubMed Abstract available

ZHOU Z, Collado A, Sun C, Tratsiakovich Y, et al
Downregulation of Erythrocyte miR-210 Induces Endothelial Dysfunction in Type 2 Diabetes.
Diabetes. 2021 Nov 9. pii: db21-0093. doi: 10.2337/db21-0093.
PubMed Abstract available

OFORI JK, Karagiannopoulos A, Nagao M, Westholm E, et al
Human Islet MicroRNA-200c is Elevated in Type 2 Diabetes and Targets the Transcription Factor ETV5 to Reduce Insulin Secretion.
Diabetes. 2021 Nov 9. pii: db21-0077. doi: 10.2337/db21-0077.
PubMed Abstract available

CAROLINA LC, Ciudin A, Sanchez E, Tinahones F, et al
Liraglutide Improves Forced Vital Capacity in Individuals With Type 2 Diabetes: Data From the Randomized Cross-Over LIRALUNG Study.
Diabetes. 2021 Nov 4. pii: db21-0688. doi: 10.2337/db21-0688.
PubMed Abstract available

YOUSRI NA, Suhre K, Yassin E, Al-Shakaki A, et al
Metabolic and Metabo-Clinical Signatures of T2D, Obesity, Retinopathy and Dyslipidemia.
Diabetes. 2021 Nov 3. pii: db21-0490. doi: 10.2337/db21-0490.
PubMed Abstract available

HOLST JJ
Treatment of Type 2 Diabetes and Obesity on the Basis of the Incretin System: The 2021 Banting Medal for Scientific Achievement Award Lecture.
Diabetes. 2021;70:2468-2475.
PubMed Abstract available

CHARLES MA, Leslie RD
Diabetes: Concepts of beta-Cell Organ Dysfunction and Failure Would Lead to Earlier Diagnoses and Prevention.
Diabetes. 2021;70:2444-2456.
PubMed Abstract available

SPARKS LM, Goodpaster BH, Bergman BC
The Metabolic Significance of Intermuscular Adipose Tissue: Is IMAT a Friend or a Foe to Metabolic Health?
Diabetes. 2021;70:2457-2467.
PubMed Abstract available

SHARMA RB, Landa-Galvan HV, Alonso LC
Living Dangerously: Protective and Harmful ER Stress Responses in Pancreatic beta-Cells.
Diabetes. 2021;70:2431-2443.
PubMed Abstract available

TONG X, Stein R
Lipid Droplets Protect Human beta-Cells From Lipotoxicity-Induced Stress and Cell Identity Changes.
Diabetes. 2021;70:2595-2607.
PubMed Abstract available

BOWKER N, Hansford R, Burgess S, Foley CN, et al
Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (GIP) Levels and Cardiovascular Disease Risk Are Driven by Distinct Causal Variants in the GIPR Region.
Diabetes. 2021;70:2706-2719.
PubMed Abstract available

October 2021

NISHIZAKI H, Matsuoka O, Kagawa T, Kobayashi A, et al
Erratum. SCO-267, a GPR40 Full Agonist, Stimulates Islet and Gut Hormone Secretion and Improves Glycemic Control in Humans. Diabetes 2021;70:2364-2376.
Diabetes. 2021 Oct 29. pii: db22-er01b. doi: 10.2337.
PubMed

GUJARATI NA, Leonardo AR, Vasquez JM, Guo Y, et al
Loss of Functional SCO2 Attenuates Oxidative Stress in Diabetic Kidney Disease.
Diabetes. 2021 Oct 26. pii: db21-0316. doi: 10.2337/db21-0316.
PubMed Abstract available

GRONDAHL MFG, Lund A, Bagger JI, Petersen TS, et al
Glucagon Clearance is Preserved in Type 2 Diabetes.
Diabetes. 2021 Oct 26. pii: db21-0024. doi: 10.2337/db21-0024.
PubMed Abstract available

METWALLY AA, Mehta P, Johnson BS, Nagarjuna A, et al
COVID-19-Induced New-Onset Diabetes: Trends and Technologies.
Diabetes. 2021 Oct 22. pii: dbi21-0029. doi: 10.2337/dbi21-0029.
PubMed Abstract available

GRONDAHL MFG, Lund A, Bagger JI, Petersen TS, et al
Glucagon Clearance is Preserved in Type 2 Diabetes.
Diabetes. 2021 Oct 21. pii: 139082. doi: 10.2337/db21-0024.
PubMed Abstract available

GUJARATI NA, Leonardo AR, Vasquez JM, Guo Y, et al
Loss of Functional SCO2 Attenuates Oxidative Stress in Diabetic Kidney Disease.
Diabetes. 2021 Oct 21. pii: 139087. doi: 10.2337/db21-0316.
PubMed Abstract available

VAZQUEZ ARREOLA E, Hanson RL, Bogardus C, Knowler WC, et al
Relationship Between Insulin Secretion and Insulin Sensitivity and its Role in Development of Type 2 Diabetes Mellitus: Beyond the Disposition Index.
Diabetes. 2021 Oct 18. pii: db21-0416. doi: 10.2337/db21-0416.
PubMed Abstract available

VAZQUEZ ARREOLA E, Hanson RL, Bogardus C, Knowler WC, et al
Relationship Between Insulin Secretion and Insulin Sensitivity and its Role in Development of Type 2 Diabetes Mellitus: Beyond the Disposition Index.
Diabetes. 2021 Oct 18. pii: 139090. doi: 10.2337/db21-0416.
PubMed Abstract available

VECCHIONE A, Jofra T, Gerosa J, Shankwitz K, et al
Reduced Follicular Regulatory T Cells in Spleen and Pancreatic Lymph Nodes of Patients With Type 1 Diabetes.
Diabetes. 2021 Oct 7. pii: db21-0091. doi: 10.2337/db21-0091.
PubMed Abstract available

SHIN J, Toyoda S, Nishitani S, Fukuhara A, et al
Possible Involvement of Adipose Tissue in Older and Obese Diabetic Patients with Coronavirus SARS-CoV-2 Infection (COVID-19) via GRP78 (BIP/HSPA5): Significance of Hyperinsulinemia Management in COVID-19.
Diabetes. 2021 Oct 6. pii: db20-1094. doi: 10.2337/db20-1094.
PubMed Abstract available

THIRUNAVUKARASU S, Jex N, Chowdhary A, Ul Hassan I, et al
Empagliflozin Treatment is Associated With Improvements in Cardiac Energetics and Function and Reductions in Myocardial Cellular Volume in Patients With Type 2 Diabetes.
Diabetes. 2021 Oct 5. pii: db21-0270. doi: 10.2337/db21-0270.
PubMed Abstract available

ROEVER L, Tse G, Biondi-Zoccai G
Perirenal Fat and Chronic Kidney Disease in Patients With Diabetes.
Diabetes. 2021;70:2190-2191.
PubMed

SRIKANTH V
Type 2 Diabetes, Glycemia, and Brain Health: The Complexity of Causality.
Diabetes. 2021;70:2187-2189.
PubMed

RUSS HA, Davidson HW
Found in Translation: Novel Insights Into Type 1 Diabetes and beta-Cell Biology.
Diabetes. 2021;70:2185-2186.
PubMed

PAN Y, Zhang MZ, Harris RC
Annexin 1 Mimetic Ac2-26 Holds Promise for the Treatment of Diabetic Nephropathy.
Diabetes. 2021;70:2183-2184.
PubMed

CHEN X, Mao Y, Hu J, Han S, et al
Perirenal Fat Thickness Is Significantly Associated With the Risk for Development of Chronic Kidney Disease in Patients With Diabetes.
Diabetes. 2021;70:2322-2332.
PubMed Abstract available

THOMAIDOU S, Slieker RC, van der Slik AR, Boom J, et al
Long RNA Sequencing and Ribosome Profiling of Inflamed beta-Cells Reveal an Extensive Translatome Landscape.
Diabetes. 2021;70:2299-2312.
PubMed Abstract available

DA SILVA AA, Hall JE, Dai X, Wang Z, et al
Chronic Antidiabetic Actions of Leptin: Evidence From Parabiosis Studies for a CNS-Derived Circulating Antidiabetic Factor.
Diabetes. 2021;70:2264-2274.
PubMed Abstract available

NISHIZAKI H, Matsuoka O, Kagawa T, Kobayashi A, et al
SCO-267, a GPR40 Full Agonist, Stimulates Islet and Gut Hormone Secretion and Improves Glycemic Control in Humans.
Diabetes. 2021;70:2364-2376.
PubMed Abstract available

LIN X, Zhang Y, He X, Chen Y, et al
The Choline Metabolite TMAO Inhibits NETosis and Promotes Placental Development in GDM of Humans and Mice.
Diabetes. 2021;70:2250-2263.
PubMed Abstract available

LU H, Guo R, Zhang Y, Su S, et al
Inhibition of lncRNA TCONS_00077866 Ameliorates the High Stearic Acid Diet-Induced Mouse Pancreatic beta-Cell Inflammatory Response by Increasing miR-297b-5p to Downregulate SAA3 Expression.
Diabetes. 2021;70:2275-2288.
PubMed Abstract available

GARFIELD V, Farmaki AE, Fatemifar G, Eastwood SV, et al
Relationship Between Glycemia and Cognitive Function, Structural Brain Outcomes, and Dementia: A Mendelian Randomization Study in the UK Biobank.
Diabetes. 2021;70:2313-2321.
PubMed Abstract available

September 2021

FERNANDEZ-DE-LAS-PENAS C, Guijarro C, Torres-Macho J, Velasco-Arribas M, et al
Diabetes and the Risk of Long-Term Post-COVID Symptoms.
Diabetes. 2021 Sep 27. pii: db21-0329. doi: 10.2337/db21-0329.
PubMed Abstract available

NYLAND JE, Raja-Khan NT, Bettermann K, Haouzi PA, et al
Diabetes, Drug Treatment and Mortality in COVID-19: A Multinational Retrospective Cohort Study.
Diabetes. 2021 Sep 27. pii: db21-0385. doi: 10.2337/db21-0385.
PubMed Abstract available

AZOURY ME, Samassa F, Buitinga M, Nigi L, et al
CD8+ T cells variably recognize native versus citrullinated GRP78 epitopes in type 1 diabetes.
Diabetes. 2021 Sep 24. pii: db21-0259. doi: 10.2337/db21-0259.
PubMed Abstract available

TURA A, Grespan E, Gobl CS, Koivula RW, et al
Profiles of Glucose Metabolism in Different Prediabetes Phenotypes, Classified by Fasting Glycemia, 2-Hour OGTT, Glycated Hemoglobin, and 1-Hour OGTT: An IMI DIRECT Study.
Diabetes. 2021;70:2092-2106.
PubMed Abstract available

HAYES MR, Borner T, De Jonghe BC
The Role of GIP in the Regulation of GLP-1 Satiety and Nausea.
Diabetes. 2021;70:1956-1961.
PubMed Abstract available

August 2021

PAGNI PP, Chaplin J, Wijaranakula M, Wesley JD, et al
Multicomponent Plasmid Protects Mice From Spontaneous Autoimmune Diabetes.
Diabetes. 2021 Aug 13. pii: 139085. doi: 10.2337/db21-0327.
PubMed Abstract available

DUNNE JL, Maizel JL, Posgai AL, Atkinson MA, et al
The Women's Leadership Gap in Diabetes: A Call for Equity and Excellence.
Diabetes. 2021;70:1623-1633.
PubMed Abstract available

SANDOVAL DA, Alonso LC, Gannon M, Sander M, et al
Career Advancement for Women in Diabetes-Related Research: Developing and Retaining Female Talent.
Diabetes. 2021;70:1634-1637.
PubMed

MUNOZ CE, Weinstock RS, Brown TD, Gabbay RA, et al
Women and the American Diabetes Association.
Diabetes. 2021;70:1638-1639.
PubMed

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