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Articles published in J Biol Chem

Retrieve available abstracts of 34 articles:
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Single Articles


    March 2017
  1. MANZAR GS, Kim EM, Zavazava N
    Demethylation of Induced Pluripotent Stem Cells from Type 1 Diabetic Patients Enhances Differentiation into Functional Pancreatic beta-cells.
    J Biol Chem. 2017 Mar 30. pii: jbc.M117.784280. doi: 10.1074/jbc.M117.784280.
    PubMed     Text format     Abstract available


    February 2017
  2. WANG XX, Levi J, Luo Y, Myakala K, et al
    SGLT2 Expression is increased in Human Diabetic Nephropathy: SGLT2 Inhibition Decreases Renal Lipid Accumulation, Inflammation and the Development of Nephropathy in Diabetic Mice.
    J Biol Chem. 2017 Feb 14. pii: jbc.M117.779520. doi: 10.1074/jbc.M117.779520.
    PubMed     Text format     Abstract available


  3. VADVALKAR SS, Matsuzaki S, Eyster CA, Giorgione JR, et al
    Decreased Mitochondrial Pyruvate Transport Activity in the Diabetic Heart: Role of MPC2 Acetylation.
    J Biol Chem. 2017 Feb 1. pii: jbc.M116.753509. doi: 10.1074/jbc.M116.753509.
    PubMed     Text format     Abstract available


    January 2017
  4. KIM SY, Lee JH, Merrins MJ, Gavrilova O, et al
    Loss of Cyclin Dependent Kinase 2 in the Pancreas Links Primary beta-cell Dysfunction to Progressive Depletion of beta-cell Mass and Diabetes.
    J Biol Chem. 2017 Jan 18. pii: jbc.M116.754077. doi: 10.1074/jbc.M116.754077.
    PubMed     Text format     Abstract available


    December 2016
  5. LEE HW, Khan SQ, Khaliqdina S, Altintas MM, et al
    Absence of miR-146a in podocytes increases risk of diabetic glomerulopathy via upregulation of erbb4 and notch-1.
    J Biol Chem. 2016 Dec 2. pii: jbc.M116.753822.
    PubMed     Text format     Abstract available


    November 2016
  6. ZHANG Y, Li Q, Youn JY, Cai H, et al
    PTP1B in Calpain-dependent Feedback Regulation of VEGFR2 in Endothelial Cells: Implication in VEGF-dependent Angiogenesis and Diabetic Wound Healing.
    J Biol Chem. 2016 Nov 21. pii: jbc.M116.766832.
    PubMed     Text format     Abstract available


  7. MERRIMAN C, Huang Q, Rutter GA, Fu D, et al
    Lipid-tuned Zinc Transport Activity of Human ZnT8 Correlates with Risk for Type-2 Diabetes.
    J Biol Chem. 2016 Nov 8. pii: jbc.M116.764605.
    PubMed     Text format     Abstract available


  8. CIVIDINI F, Scott BT, Dai A, Han W, et al
    O-GlcNAcylation of Ogg1 Impairs Oxidative Mitochondrial DNA Lesion Repair in Diabetic Hearts.
    J Biol Chem. 2016 Nov 5. pii: jbc.M116.754481.
    PubMed     Text format     Abstract available


    October 2016
  9. YIN QH, Zhang R, Li L, Wang YT, et al
    Exendin-4 Ameliorates Lipotoxicity-induced Glomerular Endothelial Cell Injury by Improving ABC Transporter A1-mediated Cholesterol Efflux in Diabetic apoE Knockout Mice.
    J Biol Chem. 2016 Oct 26. pii: jbc.M116.730564.
    PubMed     Text format     Abstract available


    September 2016
  10. MAGANTI AV, Tersey SA, Syed F, Nelson JB, et al
    Peroxisome Proliferator-Activated Receptor-gamma Activation Augments the beta Cell Unfolded Protein Response and Rescues Early Glycemic Deterioration and beta Cell Death in Non-Obese Diabetic Mice.
    J Biol Chem. 2016 Sep 9. pii: jbc.M116.741694.
    PubMed     Text format     Abstract available


  11. MAKITA N, Sato T, Yajima-Shoji Y, Sato J, et al
    Analysis of the V2 vasopressin receptor (V2R) mutations causing partial nephrogenic diabetes insipidus highlights a sustainable signaling by a non-peptide V2R agonist.
    J Biol Chem. 2016 Sep 6. pii: jbc.M116.733220.
    PubMed     Text format     Abstract available


    August 2016
  12. WANG M, Liu H, Zheng J, Chen B, et al
    A deafness and diabetes associated tRNA mutation caused the deficient pseudouridinylation at position 55 in tRNAGlu and mitochondrial dysfunction .
    J Biol Chem. 2016 Aug 12. pii: jbc.M116.739482.
    PubMed     Text format     Abstract available


    July 2016
  13. WU P, Yan Y, Ma LL, Hou BY, et al
    Effects of the Nrf2 Modulator Salvianolic Acid A Alone or Combined With Metformin on Diabetes-Associated Macrovascular and Renal Injury.
    J Biol Chem. 2016 Jul 14. pii: jbc.M115.712703.
    PubMed     Text format     Abstract available


    June 2016
  14. SUN J, Mao LQ, Polonsky KS, Ren DC, et al
    Pancreatic beta-Cell Death due to Pdx-1 Deficiency Requires Multi-BH Domain Protein Bax but Not Bak.
    J Biol Chem. 2016;291:13529-34.
    PubMed     Text format     Abstract available


    May 2016
  15. RAJAN MR, Nyman E, Kjolhede P, Cedersund G, et al
    Systems-Wide Experimental and Modeling Analysis of Insulin Signaling through FOXO1 in Human Adipocytes, Normally and in Type 2 Diabetes.
    J Biol Chem. 2016 May 20. pii: jbc.M116.715763.
    PubMed     Text format     Abstract available


  16. WAKABAYASHI T, Hidaka R, Fujimaki S, Asashima M, et al
    Diabetes Impairs Wnt3-Induced Neurogenesis in Olfactory Bulbs via glutamate transporter 1 inhibition.
    J Biol Chem. 2016 May 20. pii: jbc.M115.672857.
    PubMed     Text format     Abstract available


  17. SPARKS AE, Chen C, Breslin MB, Lan MS, et al
    Functional Domains of Autoimmune Regulator (AIRE) Modulate INS-VNTR Transcription in Human Thymic Epithelial Cells.
    J Biol Chem. 2016;291:11313-22.
    PubMed     Text format     Abstract available


  18. MENG X, Guo J, Fang W, Dou L, et al
    Liver MicroRNA-291b-3p Promotes Hepatic Lipogenesis through Negative Regulation of Adenosine 5'-Monophosphate (AMP)-activated Protein Kinase alpha1.
    J Biol Chem. 2016;291:10625-34.
    PubMed     Text format     Abstract available


  19. BOKORI-BROWN M, Petrov PG, Khafaji MA, Mughal MK, et al
    Red Blood Cell Susceptibility to Pneumolysin: CORRELATION WITH MEMBRANE BIOCHEMICAL AND PHYSICAL PROPERTIES.
    J Biol Chem. 2016;291:10210-27.
    PubMed     Text format     Abstract available


  20. SALABEI JK, Lorkiewicz PK, Mehra P, Gibb AA, et al
    Type 2 Diabetes Dysregulates Glucose Metabolism in Cardiac Progenitor Cells.
    J Biol Chem. 2016 May 5. pii: jbc.M116.722496.
    PubMed     Text format     Abstract available


    April 2016
  21. LI Y, Cooper A, Odibo IN, Ahmed A, et al
    Discrepancy in Insulin Regulation between Gestational Diabetes Mellitus (GDM) Platelets and Placenta.
    J Biol Chem. 2016;291:9657-65.
    PubMed     Text format     Abstract available


  22. KUO T, Kim-Muller JY, McGraw TE, Accili D, et al
    Altered Plasma Profile of Antioxidant Proteins as an Early Correlate of Pancreatic beta Cell Dysfunction.
    J Biol Chem. 2016;291:9648-56.
    PubMed     Text format     Abstract available


  23. HONG K, Xu G, Grayson TB, Shalev A, et al
    Cytokines Regulate beta-Cell Thioredoxin-interacting Protein (TXNIP) via Distinct Mechanisms and Pathways.
    J Biol Chem. 2016;291:8428-39.
    PubMed     Text format     Abstract available


    March 2016
  24. GARYU JW, Uduman M, Stewart A, Rui J, et al
    Characterization of diabetogenic CD8+ T cells: immune therapy with metabolic blockade.
    J Biol Chem. 2016 Mar 18. pii: jbc.M115.713362.
    PubMed     Text format     Abstract available


  25. KIM-MULLER JY, Kim YJ, Fan J, Zhao S, et al
    FoxO1 Deacetylation Decreases Fatty Acid Oxidation in beta-cells and Sustains Insulin Secretion in Diabetes.
    J Biol Chem. 2016 Mar 16. pii: jbc.M115.705608.
    PubMed     Text format     Abstract available


  26. NIEVES-CINTRON M, Nystoriak MA, Prada MP, Johnson K, et al
    Selective down-regulation of KV2.1 function contributes to enhanced arterial tone during diabetes.
    J Biol Chem. 2016;291:4912.
    PubMed     Text format    


  27. GREIFENHAGEN U, Frolov A, Bl Uumlher M, Hoffmann R, et al
    Plasma Proteins Modified by Advanced Glycation Endproducts (AGEs) Reveal Site-specific Susceptibilities to Glycemic Control in Patients with Type 2 Diabetes.
    J Biol Chem. 2016 Mar 1. pii: jbc.M115.702860.
    PubMed     Text format     Abstract available


    January 2016
  28. SUN L, Dutta RK, Xie P, Kanwar YS, et al
    Myoinositol Oxygenase Over-Expression Accentuates Generation of Reactive Oxygen Species and Exacerbates Cellular Injury Following High Glucose Ambience: A New Mechanism Relevant to the Pathogenesis of Diabetic Nephropathy.
    J Biol Chem. 2016 Jan 20. pii: jbc.M115.669952.
    PubMed     Text format     Abstract available


  29. RAHMAN MH, Jha MK, Kim JH, Nam Y, et al
    Pyruvate Dehydrogenase Kinase-Mediated Glycolytic Metabolic Shift in the Dorsal Root Ganglion Drives Painful Diabetic Neuropathy.
    J Biol Chem. 2016 Jan 14. pii: jbc.M115.699215.
    PubMed     Text format     Abstract available


    December 2015
  30. KANG S, Dahl R, Hsieh W, Shin AC, et al
    Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders.
    J Biol Chem. 2015 Dec 23. pii: jbc.M115.705012.
    PubMed     Text format     Abstract available


    November 2015
  31. KRYVALAP Y, Lo CW, Manuylova E, Baldzizhar R, et al
    Antibody Response to Serpin B13 Induces Adaptive Changes in Mouse Pancreatic Islets and Slows Down the Decline in the Residual Beta Cell Function in Children with Recent Onset in Type 1 Diabetes Mellitus.
    J Biol Chem. 2015 Nov 17. pii: jbc.M115.687848.
    PubMed     Text format     Abstract available


  32. TOMINAGA T, Dutta RK, Joladarashi D, Doi T, et al
    Transcriptional and Translational Modulation of Myo-Inositol Oxygenase (MIOX) by Fatty acids: Implications in Renal Tubular Injury Induced in Obesity and Diabetes.
    J Biol Chem. 2015 Nov 17. pii: jbc.M115.698191.
    PubMed     Text format     Abstract available


  33. SRIRAM S, Subramanian S, Juvvuna PK, McFarlane C, et al
    Myostatin induces DNA damage in skeletal muscle of streptozotocin-induced type 1 diabetic mice.
    J Biol Chem. 2015;290:27012.
    PubMed     Text format    


    August 2015
  34. LI R, Uttarwar L, Gao B, Charbonneau M, et al
    High Glucose Up-regulates ADAM17 through HIF-1alpha in Mesangial Cells.
    J Biol Chem. 2015;290:21603-14.
    PubMed     Text format     Abstract available


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