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Articles published in Science

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Single Articles


    March 2018
  1. MURE LS, Le HD, Benegiamo G, Chang MW, et al
    Diurnal transcriptome atlas of a primate across major neural and peripheral tissues.
    Science. 2018;359.
    PubMed     Text format     Abstract available


  2. ZHAO L, Zhang F, Ding X, Wu G, et al
    Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes.
    Science. 2018;359:1151-1156.
    PubMed     Text format     Abstract available


  3. SMITH LM, Kelleher NL
    Proteoforms as the next proteomics currency.
    Science. 2018;359:1106-1107.
    PubMed     Text format    


    February 2018
  4. VLACHOGIANNIS G, Hedayat S, Vatsiou A, Jamin Y, et al
    Patient-derived organoids model treatment response of metastatic gastrointestinal cancers.
    Science. 2018;359:920-926.
    PubMed     Text format     Abstract available


  5. MIAO D, Margolis CA, Gao W, Voss MH, et al
    Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma.
    Science. 2018;359:801-806.
    PubMed     Text format     Abstract available


  6. GIBCUS JH, Samejima K, Goloborodko A, Samejima I, et al
    A pathway for mitotic chromosome formation.
    Science. 2018;359.
    PubMed     Text format     Abstract available


    January 2018
  7. KONG A, Thorleifsson G, Frigge ML, Vilhjalmsson BJ, et al
    The nature of nurture: Effects of parental genotypes.
    Science. 2018;359:424-428.
    PubMed     Text format     Abstract available


  8. LERNER E, Cordes T, Ingargiola A, Alhadid Y, et al
    Toward dynamic structural biology: Two decades of single-molecule Forster resonance energy transfer.
    Science. 2018;359.
    PubMed     Text format     Abstract available


  9. FITZPATRICK MJ, Edelsparre AH
    The genomics of climate change.
    Science. 2018;359:29-30.
    PubMed     Text format    


    December 2017
  10. AILLAUD C, Bosc C, Peris L, Bosson A, et al
    Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation.
    Science. 2017;358:1448-1453.
    PubMed     Text format     Abstract available


  11. EMERSON C, James S, Littler K, Randazzo FF, et al
    Principles for gene drive research.
    Science. 2017;358:1135-1136.
    PubMed     Text format    


  12. EISENBERG R, Varmus H
    Insurance for broad genomic tests in oncology.
    Science. 2017;358:1133-1134.
    PubMed     Text format    


  13. KLAEGER S, Heinzlmeir S, Wilhelm M, Polzer H, et al
    The target landscape of clinical kinase drugs.
    Science. 2017;358.
    PubMed     Text format     Abstract available


  14. COLES VJ, Stukel MR, Brooks MT, Burd A, et al
    Ocean biogeochemistry modeled with emergent trait-based genomics.
    Science. 2017;358:1149-1154.
    PubMed     Text format     Abstract available


    October 2017
  15. PENNISI E
    Untangling spider biology.
    Science. 2017;358:288-291.
    PubMed     Text format    


  16. KELSEY G, Stegle O, Reik W
    Single-cell epigenomics: Recording the past and predicting the future.
    Science. 2017;358:69-75.
    PubMed     Text format     Abstract available


  17. STUBBINGTON MJT, Rozenblatt-Rosen O, Regev A, Teichmann SA, et al
    Single-cell transcriptomics to explore the immune system in health and disease.
    Science. 2017;358:58-63.
    PubMed     Text format     Abstract available


  18. ZAHN LM
    A Fantastic Voyage in Genomics.
    Science. 2017;358:56-57.
    PubMed     Text format    


    September 2017
  19. CARLTON JT, Chapman JW, Geller JB, Miller JA, et al
    Tsunami-driven rafting: Transoceanic species dispersal and implications for marine biogeography.
    Science. 2017;357:1402-1406.
    PubMed     Text format     Abstract available


  20. SERVICE RF
    Keeping the faith.
    Science. 2017;357:1088-1091.
    PubMed     Text format    


  21. WHITTAKER RJ, Fernandez-Palacios JM, Matthews TJ, Borregaard MK, et al
    Island biogeography: Taking the long view of nature's laboratories.
    Science. 2017;357.
    PubMed     Text format     Abstract available


    August 2017
  22. JAGADEESH KA, Wu DJ, Birgmeier JA, Boneh D, et al
    Deriving genomic diagnoses without revealing patient genomes.
    Science. 2017;357:692-695.
    PubMed     Text format     Abstract available


  23. SPANG A, Caceres EF, Ettema TJG
    Genomic exploration of the diversity, ecology, and evolution of the archaeal domain of life.
    Science. 2017;357.
    PubMed     Text format     Abstract available


  24. SWARTS K, Gutaker RM, Benz B, Blake M, et al
    Genomic estimation of complex traits reveals ancient maize adaptation to temperate North America.
    Science. 2017;357:512-515.
    PubMed     Text format     Abstract available


  25. NGUYEN AT, Prado MA, Schmidt PJ, Sendamarai AK, et al
    UBE2O remodels the proteome during terminal erythroid differentiation.
    Science. 2017;357.
    PubMed     Text format     Abstract available


    June 2017
  26. TYLER DS, Vappiani J, Caneque T, Lam EYN, et al
    Click chemistry enables preclinical evaluation of targeted epigenetic therapies.
    Science. 2017;356:1397-1401.
    PubMed     Text format     Abstract available


    May 2017
  27. GIBBONS A
    Busting myths of origin.
    Science. 2017;356:678-681.
    PubMed     Text format    


  28. YEHIA L
    Lucking into science.
    Science. 2017;356:654.
    PubMed     Text format    


  29. HUGHES TR, Lambert SA
    Transcription factors read epigenetics.
    Science. 2017;356:489-490.
    PubMed     Text format    


    April 2017
  30. CHEN C, Xing D, Tan L, Li H, et al
    Single-cell whole-genome analyses by Linear Amplification via Transposon Insertion (LIANTI).
    Science. 2017;356:189-194.
    PubMed     Text format     Abstract available


  31. SCHULZ F, Yutin N, Ivanova NN, Ortega DR, et al
    Giant viruses with an expanded complement of translation system components.
    Science. 2017;356:82-85.
    PubMed     Text format     Abstract available


  32. LESLIE M
    Cell-like giant viruses found.
    Science. 2017;356:15-16.
    PubMed     Text format    


    March 2017
  33. MITCHELL LA, Wang A, Stracquadanio G, Kuang Z, et al
    Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond.
    Science. 2017;355.
    PubMed     Text format     Abstract available


  34. SHEN Y, Wang Y, Chen T, Gao F, et al
    Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome.
    Science. 2017;355.
    PubMed     Text format     Abstract available


  35. PENNISI E
    Sequencing all life captivates biologists.
    Science. 2017;355:894-895.
    PubMed     Text format    


  36. GREENE MI, Moore JS
    Peter C. Nowell (1928-2016).
    Science. 2017;355:913.
    PubMed     Text format    


    February 2017
  37. LEUENBERGER P, Ganscha S, Kahraman A, Cappelletti V, et al
    Cell-wide analysis of protein thermal unfolding reveals determinants of thermostability.
    Science. 2017;355.
    PubMed     Text format     Abstract available


  38. CHEN L, Liu P, Evans TC Jr, Ettwiller LM, et al
    DNA damage is a pervasive cause of sequencing errors, directly confounding variant identification.
    Science. 2017;355:752-756.
    PubMed     Text format     Abstract available


  39. ESVELT KM
    Precaution: Open gene drive research.
    Science. 2017;355:589-590.
    PubMed     Text format    


  40. LIN S, Yang X, Jia S, Weeks AM, et al
    Redox-based reagents for chemoselective methionine bioconjugation.
    Science. 2017;355:597-602.
    PubMed     Text format     Abstract available


    January 2017
  41. WILF P, Carvalho MR, Gandolfo MA, Cuneo NR, et al
    Eocene lantern fruits from Gondwanan Patagonia and the early origins of Solanaceae.
    Science. 2017;355:71-75.
    PubMed     Text format     Abstract available


    November 2016
  42. EVRONY GD
    One brain, many genomes.
    Science. 2016;354:557-558.
    PubMed     Text format    


    October 2016
  43. PATEL CH, Powell JD
    Warburg meets epigenetics.
    Science. 2016;354:419-420.
    PubMed     Text format    


  44. DE MANUEL M, Kuhlwilm M, Frandsen P, Sousa VC, et al
    Chimpanzee genomic diversity reveals ancient admixture with bonobos.
    Science. 2016;354:477-481.
    PubMed     Text format     Abstract available


  45. ZHENG K, Ngo PD, Owens VL, Yang XP, et al
    The biosynthetic pathway of coenzyme F430 in methanogenic and methanotrophic archaea.
    Science. 2016;354:339-342.
    PubMed     Text format     Abstract available


  46. STUDER RA, Rodriguez-Mias RA, Haas KM, Hsu JI, et al
    Evolution of protein phosphorylation across 18 fungal species.
    Science. 2016;354:229-232.
    PubMed     Text format     Abstract available



  47. Role for migratory wild birds in the global spread of avian influenza H5N8.
    Science. 2016;354:213-217.
    PubMed     Text format     Abstract available


  48. YOSEF N, Regev A
    Writ large: Genomic dissection of the effect of cellular environment on immune response.
    Science. 2016;354:64-68.
    PubMed     Text format     Abstract available


    September 2016
  49. SMITH EJ
    Doing science while black.
    Science. 2016;353:1586.
    PubMed     Text format    


  50. SANJANA NE, Wright J, Zheng K, Shalem O, et al
    High-resolution interrogation of functional elements in the noncoding genome.
    Science. 2016;353:1545-1549.
    PubMed     Text format     Abstract available


  51. MIRALDO A, Li S, Borregaard MK, Florez-Rodriguez A, et al
    An Anthropocene map of genetic diversity.
    Science. 2016;353:1532-1535.
    PubMed     Text format     Abstract available


  52. YEAMAN S, Hodgins KA, Lotterhos KE, Suren H, et al
    Convergent local adaptation to climate in distantly related conifers.
    Science. 2016;353:1431-1433.
    PubMed     Text format     Abstract available


    August 2016
  53. WALLEY JW, Sartor RC, Shen Z, Schmitz RJ, et al
    Integration of omic networks in a developmental atlas of maize.
    Science. 2016;353:814-8.
    PubMed     Text format     Abstract available


    July 2016
  54. PENNISI E
    SYMBIOSIS. A lichen menage a trois.
    Science. 2016;353:337.
    PubMed     Text format    


  55. PENNISI E
    EVOLUTIONARY BIOLOGY. Do genomic conflicts drive evolution?
    Science. 2016;353:334-5.
    PubMed     Text format    


  56. BOEKE JD, Church G, Hessel A, Kelley NJ, et al
    GENOME ENGINEERING. The Genome Project-Write.
    Science. 2016;353:126-7.
    PubMed     Text format    


    June 2016
  57. WILLIAMS EG, Wu Y, Jha P, Dubuis S, et al
    Systems proteomics of liver mitochondria function.
    Science. 2016;352:aad0189.
    PubMed     Text format     Abstract available



  58. GENOMICS. A federated ecosystem for sharing genomic, clinical data.
    Science. 2016;352:1278-80.
    PubMed     Text format    


  59. FRANTZ LA, Mullin VE, Pionnier-Capitan M, Lebrasseur O, et al
    Genomic and archaeological evidence suggest a dual origin of domestic dogs.
    Science. 2016;352:1228-31.
    PubMed     Text format     Abstract available


    May 2016
  60. SHEMA E, Jones D, Shoresh N, Donohue L, et al
    Single-molecule decoding of combinatorially modified nucleosomes.
    Science. 2016;352:717-21.
    PubMed     Text format     Abstract available


    April 2016
  61. ZHERNAKOVA A, Kurilshikov A, Bonder MJ, Tigchelaar EF, et al
    Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity.
    Science. 2016;352:565-9.
    PubMed     Text format     Abstract available


  62. WADE L
    BRAIN DRAIN. Mexico struggles to woo expat genome jocks.
    Science. 2016;352:507.
    PubMed     Text format    


  63. LAMICHHANEY S, Han F, Berglund J, Wang C, et al
    A beak size locus in Darwin's finches facilitated character displacement during a drought.
    Science. 2016;352:470-4.
    PubMed     Text format     Abstract available


  64. PENNISI E
    EVOLUTION. Templeton grant funds evolution rethink.
    Science. 2016;352:394-5.
    PubMed     Text format    


  65. TIROSH I, Izar B, Prakadan SM, Wadsworth MH 2nd, et al
    Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq.
    Science. 2016;352:189-96.
    PubMed     Text format     Abstract available


  66. GORDON D, Huddleston J, Chaisson MJ, Hill CM, et al
    Long-read sequence assembly of the gorilla genome.
    Science. 2016;352:aae0344.
    PubMed     Text format     Abstract available


  67. RUBEN A
    Of mice and mics.
    Science. 2016;352:110.
    PubMed     Text format    


    March 2016
  68. DOVE ES, Townend D, Meslin EM, Bobrow M, et al
    RESEARCH ETHICS. Ethics review for international data-intensive research.
    Science. 2016;351:1399-400.
    PubMed     Text format    


  69. FARIA NR, Azevedo RD, Kraemer MU, Souza R, et al
    Zika virus in the Americas: Early epidemiological and genetic findings.
    Science. 2016 Mar 24. pii: aaf5036.
    PubMed     Text format     Abstract available


  70. BIDINOSTI M, Botta P, Kruttner S, Proenca CC, et al
    CLK2 inhibition ameliorates autistic features associated with SHANK3 deficiency.
    Science. 2016;351:1199-203.
    PubMed     Text format     Abstract available


    February 2016
  71. PENNISI E
    Genomics. Pocket DNA sequencers make real-time diagnostics a reality.
    Science. 2016;351:800-1.
    PubMed     Text format    


  72. YUDELL M, Roberts D, DeSalle R, Tishkoff S, et al
    SCIENCE AND SOCIETY. Taking race out of human genetics.
    Science. 2016;351:564-5.
    PubMed     Text format    


    January 2016
  73. HEDLEY PL, Christiansen M
    A necrogenomic registry's potential.
    Science. 2016;351:456.
    PubMed     Text format    


  74. MAIXNER F, Krause-Kyora B, Turaev D, Herbig A, et al
    The 5300-year-old Helicobacter pylori genome of the Iceman.
    Science. 2016;351:162-5.
    PubMed     Text format     Abstract available


  75. KAISER J
    BIOMEDICAL RESOURCES. Funding for key data resources in jeopardy.
    Science. 2016;351:14.
    PubMed     Text format    


    December 2015
  76. TSAI JW
    The M.D.-Ph.D. double agent.
    Science. 2015;350:1434.
    PubMed     Text format    


  77. AMIGO I
    Science made me a better parent.
    Science. 2015;350:1286.
    PubMed     Text format    


  78. ALEXANDROV LB
    Understanding the origins of human cancer.
    Science. 2015;350:1175.
    PubMed     Text format    


    November 2015
  79. MARTINY JB, Jones SE, Lennon JT, Martiny AC, et al
    Microbiomes in light of traits: A phylogenetic perspective.
    Science. 2015;350:aac9323.
    PubMed     Text format     Abstract available


    October 2015
  80. RADICK G
    HISTORY OF SCIENCE. Beyond the "Mendel-Fisher controversy".
    Science. 2015;350:159-60.
    PubMed     Text format    


  81. BALTER M
    BEHAVIORAL GENETICS. Can epigenetics explain homosexuality puzzle?
    Science. 2015;350:148.
    PubMed     Text format    


  82. VAN ALLEN EM, Miao D, Schilling B, Shukla SA, et al
    Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.
    Science. 2015;350:207-11.
    PubMed     Text format     Abstract available


    September 2015
  83. GESCHWIND DH, Flint J
    Genetics and genomics of psychiatric disease.
    Science. 2015;349:1489-94.
    PubMed     Text format     Abstract available


  84. KAISER J
    Who has your DNA--or wants it.
    Science. 2015;349:1475.
    PubMed     Text format    


  85. KAISER J
    BIOMEDICINE. NIH opens precision medicine study to nation.
    Science. 2015;349:1433.
    PubMed     Text format    


  86. KOREM T, Zeevi D, Suez J, Weinberger A, et al
    Growth dynamics of gut microbiota in health and disease inferred from single metagenomic samples.
    Science. 2015;349:1101-6.
    PubMed     Text format     Abstract available


    August 2015
  87. DAVISON J, Moora M, Opik M, Adholeya A, et al
    FUNGAL SYMBIONTS. Global assessment of arbuscular mycorrhizal fungus diversity reveals very low endemism.
    Science. 2015;349:970-3.
    PubMed     Text format     Abstract available


  88. AKBARI OS, Bellen HJ, Bier E, Bullock SL, et al
    BIOSAFETY. Safeguarding gene drive experiments in the laboratory.
    Science. 2015;349:927-9.
    PubMed     Text format    


  89. RAGHAVAN M, Steinrucken M, Harris K, Schiffels S, et al
    POPULATION GENETICS. Genomic evidence for the Pleistocene and recent population history of Native Americans.
    Science. 2015;349:aab3884.
    PubMed     Text format     Abstract available


  90. TEICHMANN S, Pain E
    Biology, wet and dry.
    Science. 2015;349:662.
    PubMed     Text format    


    July 2015
  91. WANG J, Normile D
    Q&A. Former head of China's genome powerhouse starts new chapter.
    Science. 2015;349:463.
    PubMed     Text format    


  92. STEWART CN JR
    Songwriting and science.
    Science. 2015;349:446.
    PubMed     Text format    


  93. LLOYD KC, Meehan T, Beaudet A, Murray S, et al
    Precision medicine: Look to the mice.
    Science. 2015;349:390.
    PubMed     Text format    


  94. SERVICE RF
    Protein power.
    Science. 2015;349:372-3.
    PubMed     Text format    


  95. MINAJIGI A, Froberg JE, Wei C, Sunwoo H, et al
    Chromosomes. A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation.
    Science. 2015;349.
    PubMed     Text format     Abstract available


  96. KOHANE IS
    HEALTH CARE POLICY. Ten things we have to do to achieve precision medicine.
    Science. 2015;349:37-8.
    PubMed     Text format    


    June 2015
  97. CAPINHA C, Essl F, Seebens H, Moser D, et al
    BIOGEOGRAPHY. The dispersal of alien species redefines biogeography in the Anthropocene.
    Science. 2015;348:1248-51.
    PubMed     Text format     Abstract available


  98. COHEN J
    MOLECULAR EPIDEMIOLOGY. HIV family trees reveal viral spread.
    Science. 2015;348:1188-9.
    PubMed     Text format    


    May 2015
  99. VILLAR E, Farrant GK, Follows M, Garczarek L, et al
    Ocean plankton. Environmental characteristics of Agulhas rings affect interocean plankton transport.
    Science. 2015;348:1261447.
    PubMed     Text format     Abstract available


  100. RASCHLE M, Smeenk G, Hansen RK, Temu T, et al
    DNA repair. Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links.
    Science. 2015;348:1253671.
    PubMed     Text format     Abstract available


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