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  HIV Infection

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Articles published in PLoS Pathog

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    November 2017
  1. MACKELPRANG RD, Bamshad MJ, Chong JX, Hou X, et al
    Whole genome sequencing of extreme phenotypes identifies variants in CD101 and UBE2V1 associated with increased risk of sexually acquired HIV-1.
    PLoS Pathog. 2017;13:e1006703.
    PubMed     Text format     Abstract available


  2. MCBRIDE JA, Striker R
    Imbalance in the game of T cells: What can the CD4/CD8 T-cell ratio tell us about HIV and health?
    PLoS Pathog. 2017;13:e1006624.
    PubMed     Text format    


    October 2017
  3. BAILEY AL, Buechler CR, Matson DR, Peterson EJ, et al
    Pegivirus avoids immune recognition but does not attenuate acute-phase disease in a macaque model of HIV infection.
    PLoS Pathog. 2017;13:e1006692.
    PubMed     Text format     Abstract available


  4. ROGANOWICZ MD, Komurlu S, Mukherjee S, Plewka J, et al
    TRIM5alpha SPRY/coiled-coil interactions optimize avid retroviral capsid recognition.
    PLoS Pathog. 2017;13:e1006686.
    PubMed     Text format     Abstract available


  5. PORTILLO JC, Muniz-Feliciano L, Lopez Corcino Y, Lee SJ, et al
    Toxoplasma gondii induces FAK-Src-STAT3 signaling during infection of host cells that prevents parasite targeting by autophagy.
    PLoS Pathog. 2017;13:e1006671.
    PubMed     Text format     Abstract available


  6. LEIBMAN RS, Richardson MW, Ellebrecht CT, Maldini CR, et al
    Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor.
    PLoS Pathog. 2017;13:e1006613.
    PubMed     Text format     Abstract available


  7. RATO S, Rausell A, Munoz M, Telenti A, et al
    Single-cell analysis identifies cellular markers of the HIV permissive cell.
    PLoS Pathog. 2017;13:e1006678.
    PubMed     Text format     Abstract available


    September 2017
  8. OBENG-ADJEI N, Portugal S, Holla P, Li S, et al
    Malaria-induced interferon-gamma drives the expansion of Tbethi atypical memory B cells.
    PLoS Pathog. 2017;13:e1006576.
    PubMed     Text format     Abstract available


  9. DEL PRETE GQ, Keele BF, Fode J, Thumar K, et al
    A single gp120 residue can affect HIV-1 tropism in macaques.
    PLoS Pathog. 2017;13:e1006572.
    PubMed     Text format     Abstract available


  10. ABERE B, Mamo TM, Hartmann S, Samarina N, et al
    The Kaposi's sarcoma-associated herpesvirus (KSHV) non-structural membrane protein K15 is required for viral lytic replication and may represent a therapeutic target.
    PLoS Pathog. 2017;13:e1006639.
    PubMed     Text format     Abstract available


  11. ALLARD A, Althouse BM, Hebert-Dufresne L, Scarpino SV, et al
    The risk of sustained sexual transmission of Zika is underestimated.
    PLoS Pathog. 2017;13:e1006633.
    PubMed     Text format     Abstract available


  12. THOMAS AS, Jones KL, Gandhi RT, McMahon DK, et al
    mT-cell responses targeting HIV Nef uniquely correlate with infected cell frequencies after long-term antiretroviral therapy.
    PLoS Pathog. 2017;13:e1006629.
    PubMed     Text format     Abstract available


  13. SEKI S, Nomura T, Nishizawa M, Yamamoto H, et al
    In vivo virulence of MHC-adapted AIDS virus serially-passaged through MHC-mismatched hosts.
    PLoS Pathog. 2017;13:e1006638.
    PubMed     Text format     Abstract available


  14. SHRESTHA P, Davis DA, Veeranna RP, Carey RF, et al
    Hypoxia-inducible factor-1 alpha as a therapeutic target for primary effusion lymphoma.
    PLoS Pathog. 2017;13:e1006628.
    PubMed     Text format     Abstract available


  15. DUBROVSKAYA V, Guenaga J, de Val N, Wilson R, et al
    Targeted N-glycan deletion at the receptor-binding site retains HIV Env NFL trimer integrity and accelerates the elicited antibody response.
    PLoS Pathog. 2017;13:e1006614.
    PubMed     Text format     Abstract available


  16. NAKANO Y, Misawa N, Juarez-Fernandez G, Moriwaki M, et al
    Correction: HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation.
    PLoS Pathog. 2017;13:e1006606.
    PubMed     Text format     Abstract available


  17. KIJAK GH, Sanders-Buell E, Chenine AL, Eller MA, et al
    Correction: Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection.
    PLoS Pathog. 2017;13:e1006620.
    PubMed     Text format     Abstract available



  18. Correction: CD4 is expressed on a heterogeneous subset of hematopoietic progenitors, which persistently harbor CXCR4 and CCR5-tropic HIV proviral genomes in vivo.
    PLoS Pathog. 2017;13:e1006617.
    PubMed     Text format     Abstract available


  19. MARSDEN MD, Loy BA, Wu X, Ramirez CM, et al
    In vivo activation of latent HIV with a synthetic bryostatin analog effects both latent cell "kick" and "kill" in strategy for virus eradication.
    PLoS Pathog. 2017;13:e1006575.
    PubMed     Text format     Abstract available


  20. TARTOUR K, Nguyen XN, Appourchaux R, Assil S, et al
    Interference with the production of infectious viral particles and bimodal inhibition of replication are broadly conserved antiviral properties of IFITMs.
    PLoS Pathog. 2017;13:e1006610.
    PubMed     Text format     Abstract available


  21. RADEMEYER C, Korber B, Seaman MS, Giorgi EE, et al
    Correction: Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization.
    PLoS Pathog. 2017;13:e1006641.
    PubMed     Text format     Abstract available


    August 2017
  22. HOTTER D, Krabbe T, Reith E, Gawanbacht A, et al
    Primate lentiviruses use at least three alternative strategies to suppress NF-kappaB-mediated immune activation.
    PLoS Pathog. 2017;13:e1006598.
    PubMed     Text format     Abstract available


  23. BURDICK RC, Delviks-Frankenberry KA, Chen J, Janaka SK, et al
    Dynamics and regulation of nuclear import and nuclear movements of HIV-1 complexes.
    PLoS Pathog. 2017;13:e1006570.
    PubMed     Text format     Abstract available


  24. GORIN AM, Du Y, Liu FY, Zhang TH, et al
    HIV-1 epitopes presented by MHC class I types associated with superior immune containment of viremia have highly constrained fitness landscapes.
    PLoS Pathog. 2017;13:e1006541.
    PubMed     Text format     Abstract available


  25. MATSUDA K, Riddick NE, Lee CA, Puryear SB, et al
    A SIV molecular clone that targets the CNS and induces neuroAIDS in rhesus macaques.
    PLoS Pathog. 2017;13:e1006538.
    PubMed     Text format     Abstract available


  26. MCCRACKEN MK, Gromowski GD, Friberg HL, Lin X, et al
    Impact of prior flavivirus immunity on Zika virus infection in rhesus macaques.
    PLoS Pathog. 2017;13:e1006487.
    PubMed     Text format     Abstract available


    July 2017
  27. LI G, Zhao J, Cheng L, Jiang Q, et al
    HIV-1 infection depletes human CD34+CD38- hematopoietic progenitor cells via pDC-dependent mechanisms.
    PLoS Pathog. 2017;13:e1006505.
    PubMed     Text format     Abstract available


  28. KIJAK GH, Sanders-Buell E, Chenine AL, Eller MA, et al
    Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection.
    PLoS Pathog. 2017;13:e1006510.
    PubMed     Text format     Abstract available


  29. SEBASTIAN NT, Zaikos TD, Terry V, Taschuk F, et al
    CD4 is expressed on a heterogeneous subset of hematopoietic progenitors, which persistently harbor CXCR4 and CCR5-tropic HIV proviral genomes in vivo.
    PLoS Pathog. 2017;13:e1006509.
    PubMed     Text format     Abstract available


  30. MARTINS MA, Shin YC, Gonzalez-Nieto L, Domingues A, et al
    Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques.
    PLoS Pathog. 2017;13:e1006529.
    PubMed     Text format     Abstract available


  31. BREZAR V, Hani L, Surenaud M, Hubert A, et al
    Negative modulation of suppressive HIV-specific regulatory T cells by IL-2 adjuvanted therapeutic vaccine.
    PLoS Pathog. 2017;13:e1006489.
    PubMed     Text format     Abstract available


  32. CARDOZO EF, Andrade A, Mellors JW, Kuritzkes DR, et al
    Treatment with integrase inhibitor suggests a new interpretation of HIV RNA decay curves that reveals a subset of cells with slow integration.
    PLoS Pathog. 2017;13:e1006478.
    PubMed     Text format     Abstract available


  33. BELL SM, Bedford T
    Modern-day SIV viral diversity generated by extensive recombination and cross-species transmission.
    PLoS Pathog. 2017;13:e1006466.
    PubMed     Text format     Abstract available


  34. HILL AL, Rosenbloom DIS, Goldstein E, Hanhauser E, et al
    Correction: Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV.
    PLoS Pathog. 2017;13:e1006488.
    PubMed     Text format     Abstract available


  35. TAKEUCHI H, Saito H, Noda T, Miyamoto T, et al
    Phosphorylation of the HIV-1 capsid by MELK triggers uncoating to promote viral cDNA synthesis.
    PLoS Pathog. 2017;13:e1006441.
    PubMed     Text format     Abstract available


  36. INTROINI A, Bostrom S, Bradley F, Gibbs A, et al
    Correction: Seminal plasma induces inflammation and enhances HIV-1 replication in human cervical tissue explants.
    PLoS Pathog. 2017;13:e1006492.
    PubMed     Text format     Abstract available


  37. ZHYVOLOUP A, Melamed A, Anderson I, Planas D, et al
    Digoxin reveals a functional connection between HIV-1 integration preference and T-cell activation.
    PLoS Pathog. 2017;13:e1006460.
    PubMed     Text format     Abstract available


    June 2017
  38. BOLTON DL, McGinnis K, Finak G, Chattopadhyay P, et al
    Combined single-cell quantitation of host and SIV genes and proteins ex vivo reveals host-pathogen interactions in individual cells.
    PLoS Pathog. 2017;13:e1006445.
    PubMed     Text format     Abstract available


  39. CAIRNS TM, Ditto NT, Lou H, Brooks BD, et al
    Global sensing of the antigenic structure of herpes simplex virus gD using high-throughput array-based SPR imaging.
    PLoS Pathog. 2017;13:e1006430.
    PubMed     Text format     Abstract available


  40. ELEMANS M, Boelen L, Rasmussen M, Buus S, et al
    HIV-1 adaptation to NK cell-mediated immune pressure.
    PLoS Pathog. 2017;13:e1006361.
    PubMed     Text format     Abstract available


  41. XU Z, Asahchop EL, Branton WG, Gelman BB, et al
    MicroRNAs upregulated during HIV infection target peroxisome biogenesis factors: Implications for virus biology, disease mechanisms and neuropathology.
    PLoS Pathog. 2017;13:e1006360.
    PubMed     Text format     Abstract available


    May 2017
  42. INTROINI A, Bostrom S, Bradley F, Gibbs A, et al
    Seminal plasma induces inflammation and enhances HIV-1 replication in human cervical tissue explants.
    PLoS Pathog. 2017;13:e1006402.
    PubMed     Text format     Abstract available


  43. KRAMER B, Goeser F, Lutz P, Glassner A, et al
    Compartment-specific distribution of human intestinal innate lymphoid cells is altered in HIV patients under effective therapy.
    PLoS Pathog. 2017;13:e1006373.
    PubMed     Text format     Abstract available


  44. SUI Y, Frey B, Wang Y, Billeskov R, et al
    Paradoxical myeloid-derived suppressor cell reduction in the bone marrow of SIV chronically infected macaques.
    PLoS Pathog. 2017;13:e1006395.
    PubMed     Text format     Abstract available


  45. NAKANO Y, Misawa N, Juarez-Fernandez G, Moriwaki M, et al
    HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation.
    PLoS Pathog. 2017;13:e1006348.
    PubMed     Text format     Abstract available


  46. FENNESSEY CM, Pinkevych M, Immonen TT, Reynaldi A, et al
    Genetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral therapy.
    PLoS Pathog. 2017;13:e1006359.
    PubMed     Text format     Abstract available


  47. BRANDENBERG OF, Magnus C, Rusert P, Gunthard HF, et al
    Predicting HIV-1 transmission and antibody neutralization efficacy in vivo from stoichiometric parameters.
    PLoS Pathog. 2017;13:e1006313.
    PubMed     Text format     Abstract available


  48. SERRANO-VILLAR S, Sainz T, Ma ZM, Utay NS, et al
    Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naive to Antiretroviral Therapy: A Pilot Randomized Trial.
    PLoS Pathog. 2017;13:e1006368.
    PubMed     Text format     Abstract available


  49. FEDER AF, Kline C, Polacino P, Cottrell M, et al
    A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host.
    PLoS Pathog. 2017;13:e1006358.
    PubMed     Text format     Abstract available


    April 2017
  50. GANDHI RT, McMahon DK, Bosch RJ, Lalama CM, et al
    Levels of HIV-1 persistence on antiretroviral therapy are not associated with markers of inflammation or activation.
    PLoS Pathog. 2017;13:e1006285.
    PubMed     Text format     Abstract available


    March 2017
  51. MOUSTAFA A, Xie C, Kirkness E, Biggs W, et al
    The blood DNA virome in 8,000 humans.
    PLoS Pathog. 2017;13:e1006292.
    PubMed     Text format     Abstract available


  52. BUI JK, Sobolewski MD, Keele BF, Spindler J, et al
    Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir.
    PLoS Pathog. 2017;13:e1006283.
    PubMed     Text format     Abstract available


  53. BEAUPARLANT D, Rusert P, Magnus C, Kadelka C, et al
    Delineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality.
    PLoS Pathog. 2017;13:e1006255.
    PubMed     Text format     Abstract available


  54. TENFORDE MW, Scriven JE, Harrison TS, Jarvis JN, et al
    Immune correlates of HIV-associated cryptococcal meningitis.
    PLoS Pathog. 2017;13:e1006207.
    PubMed     Text format    


    February 2017
  55. YODER AC, Guo K, Dillon SM, Phang T, et al
    The transcriptome of HIV-1 infected intestinal CD4+ T cells exposed to enteric bacteria.
    PLoS Pathog. 2017;13:e1006226.
    PubMed     Text format     Abstract available


  56. YASEN A, Herrera R, Rosbe K, Lien K, et al
    Release of HIV-1 sequestered in the vesicles of oral and genital mucosal epithelial cells by epithelial-lymphocyte interaction.
    PLoS Pathog. 2017;13:e1006247.
    PubMed     Text format     Abstract available


  57. EASTERHOFF D, Moody MA, Fera D, Cheng H, et al
    Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.
    PLoS Pathog. 2017;13:e1006182.
    PubMed     Text format     Abstract available


  58. BUI JK, Halvas EK, Fyne E, Sobolewski MD, et al
    Ex vivo activation of CD4+ T-cells from donors on suppressive ART can lead to sustained production of infectious HIV-1 from a subset of infected cells.
    PLoS Pathog. 2017;13:e1006230.
    PubMed     Text format     Abstract available


  59. IRIMIA A, Serra AM, Sarkar A, Jacak R, et al
    Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.
    PLoS Pathog. 2017;13:e1006212.
    PubMed     Text format     Abstract available


  60. TANWAR HS, Khoo KK, Garvey M, Waddington L, et al
    The thermodynamics of Pr55Gag-RNA interaction regulate the assembly of HIV.
    PLoS Pathog. 2017;13:e1006221.
    PubMed     Text format     Abstract available


  61. HU Y, O'Boyle K, Auer J, Raju S, et al
    Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFkappaBeta signaling by stabilizing IkappaBalpha.
    PLoS Pathog. 2017;13:e1006187.
    PubMed     Text format     Abstract available


  62. COMPTON AA, Schwartz O
    They Might Be Giants: Does Syncytium Formation Sink or Spread HIV Infection?
    PLoS Pathog. 2017;13:e1006099.
    PubMed     Text format    


  63. NEIDLEMAN JA, Chen JC, Kohgadai N, Muller JA, et al
    Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells.
    PLoS Pathog. 2017;13:e1006163.
    PubMed     Text format     Abstract available


  64. MAIDJI E, Somsouk M, Rivera JM, Hunt PW, et al
    Replication of CMV in the gut of HIV-infected individuals and epithelial barrier dysfunction.
    PLoS Pathog. 2017;13:e1006202.
    PubMed     Text format     Abstract available


    January 2017
  65. HAMMONDS JE, Beeman N, Ding L, Takushi S, et al
    Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1.
    PLoS Pathog. 2017;13:e1006181.
    PubMed     Text format     Abstract available


  66. DORIA-ROSE NA, Altae-Tran HR, Roark RS, Schmidt SD, et al
    Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting.
    PLoS Pathog. 2017;13:e1006148.
    PubMed     Text format     Abstract available


  67. VIOLLET C, Davis DA, Tekeste SS, Reczko M, et al
    RNA Sequencing Reveals that Kaposi Sarcoma-Associated Herpesvirus Infection Mimics Hypoxia Gene Expression Signature.
    PLoS Pathog. 2017;13:e1006143.
    PubMed     Text format     Abstract available


  68. OLIVEIRA MF, Chaillon A, Nakazawa M, Vargas M, et al
    Early Antiretroviral Therapy is Associated with Lower HIV DNA Molecular Diversity and Lower Inflammation in Cerebrospinal Fluid but Does Not Prevent the Establishment of Compartmentalized HIV DNA Populations.
    PLoS Pathog. 2017;13:e1006112.
    PubMed     Text format     Abstract available


  69. WIBMER CK, Gorman J, Ozorowski G, Bhiman JN, et al
    Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.
    PLoS Pathog. 2017;13:e1006074.
    PubMed     Text format     Abstract available


  70. WERTHEIM JO, Kosakovsky Pond SL, Forgione LA, Mehta SR, et al
    Social and Genetic Networks of HIV-1 Transmission in New York City.
    PLoS Pathog. 2017;13:e1006000.
    PubMed     Text format     Abstract available


  71. AWASTHI S, Hook LM, Shaw CE, Pahar B, et al
    An HSV-2 Trivalent Vaccine Is Immunogenic in Rhesus Macaques and Highly Efficacious in Guinea Pigs.
    PLoS Pathog. 2017;13:e1006141.
    PubMed     Text format     Abstract available


  72. HEL Z, Xu J, Denning WL, Helton ES, et al
    Dysregulation of Systemic and Mucosal Humoral Responses to Microbial and Food Antigens as a Factor Contributing to Microbial Translocation and Chronic Inflammation in HIV-1 Infection.
    PLoS Pathog. 2017;13:e1006087.
    PubMed     Text format     Abstract available


    December 2016
  73. ROBERTS ER, Carnathan DG, Li H, Shaw GM, et al
    Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques.
    PLoS Pathog. 2016;12:e1006135.
    PubMed     Text format     Abstract available


  74. KHASNIS MD, Halkidis K, Bhardwaj A, Root MJ, et al
    Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer.
    PLoS Pathog. 2016;12:e1006098.
    PubMed     Text format     Abstract available


  75. ADNAN S, Reeves RK, Gillis J, Wong FE, et al
    Persistent Low-Level Replication of SIVDeltanef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection.
    PLoS Pathog. 2016;12:e1006104.
    PubMed     Text format     Abstract available


  76. HADDOX HK, Dingens AS, Bloom JD
    Experimental Estimation of the Effects of All Amino-Acid Mutations to HIV's Envelope Protein on Viral Replication in Cell Culture.
    PLoS Pathog. 2016;12:e1006114.
    PubMed     Text format     Abstract available


  77. ERICSEN AJ, Lauck M, Mohns MS, DiNapoli SR, et al
    Microbial Translocation and Inflammation Occur in Hyperacute Immunodeficiency Virus Infection and Compromise Host Control of Virus Replication.
    PLoS Pathog. 2016;12:e1006048.
    PubMed     Text format     Abstract available


  78. MEURIS F, Carthagena L, Jaracz-Ros A, Gaudin F, et al
    The CXCL12/CXCR4 Signaling Pathway: A New Susceptibility Factor in Human Papillomavirus Pathogenesis.
    PLoS Pathog. 2016;12:e1006039.
    PubMed     Text format     Abstract available


  79. STABELL AC, Hawkins J, Li M, Gao X, et al
    Non-human Primate Schlafen11 Inhibits Production of Both Host and Viral Proteins.
    PLoS Pathog. 2016;12:e1006066.
    PubMed     Text format     Abstract available


    November 2016
  80. BOULLE M, Muller TG, Dahling S, Ganga Y, et al
    HIV Cell-to-Cell Spread Results in Earlier Onset of Viral Gene Expression by Multiple Infections per Cell.
    PLoS Pathog. 2016;12:e1005964.
    PubMed     Text format     Abstract available


  81. NIKOLOVA M, Wiedemann A, Muhtarova M, Achkova D, et al
    Subset- and Antigen-Specific Effects of Treg on CD8+ T Cell Responses in Chronic HIV Infection.
    PLoS Pathog. 2016;12:e1005995.
    PubMed     Text format     Abstract available


  82. DUENAS-DECAMP M, Jiang L, Bolon D, Clapham PR, et al
    Saturation Mutagenesis of the HIV-1 Envelope CD4 Binding Loop Reveals Residues Controlling Distinct Trimer Conformations.
    PLoS Pathog. 2016;12:e1005988.
    PubMed     Text format     Abstract available


  83. LESLIE GJ, Wang J, Richardson MW, Haggarty BS, et al
    Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino Terminus.
    PLoS Pathog. 2016;12:e1005983.
    PubMed     Text format     Abstract available


  84. SMITH SA, Burton SL, Kilembe W, Lakhi S, et al
    Diversification in the HIV-1 Envelope Hyper-variable Domains V2, V4, and V5 and Higher Probability of Transmitted/Founder Envelope Glycosylation Favor the Development of Heterologous Neutralization Breadth.
    PLoS Pathog. 2016;12:e1005989.
    PubMed     Text format     Abstract available


  85. WHITE CH, Moesker B, Beliakova-Bethell N, Martins LJ, et al
    Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model.
    PLoS Pathog. 2016;12:e1006026.
    PubMed     Text format     Abstract available


  86. PRODGER JL, Gray RH, Shannon B, Shahabi K, et al
    Chemokine Levels in the Penile Coronal Sulcus Correlate with HIV-1 Acquisition and Are Reduced by Male Circumcision in Rakai, Uganda.
    PLoS Pathog. 2016;12:e1006025.
    PubMed     Text format     Abstract available


  87. LIN Z, Cantone J, Lu H, Nowicka-Sans B, et al
    Mechanistic Studies and Modeling Reveal the Origin of Differential Inhibition of Gag Polymorphic Viruses by HIV-1 Maturation Inhibitors.
    PLoS Pathog. 2016;12:e1005990.
    PubMed     Text format     Abstract available


    October 2016
  88. MILES B, Miller SM, Folkvord JM, Levy DN, et al
    Follicular Regulatory CD8 T Cells Impair the Germinal Center Response in SIV and Ex Vivo HIV Infection.
    PLoS Pathog. 2016;12:e1005924.
    PubMed     Text format     Abstract available


  89. WITTKOPP CJ, Adolph MB, Wu LI, Chelico L, et al
    A Single Nucleotide Polymorphism in Human APOBEC3C Enhances Restriction of Lentiviruses.
    PLoS Pathog. 2016;12:e1005865.
    PubMed     Text format     Abstract available


  90. SUTTIPRAPA S, Rinaldi G, Tsai IJ, Mann VH, et al
    HIV-1 Integrates Widely throughout the Genome of the Human Blood Fluke Schistosoma mansoni.
    PLoS Pathog. 2016;12:e1005931.
    PubMed     Text format     Abstract available


    September 2016
  91. POLICICCHIO BB, Xu C, Brocca-Cofano E, Raehtz KD, et al
    Multi-dose Romidepsin Reactivates Replication Competent SIV in Post-antiretroviral Rhesus Macaque Controllers.
    PLoS Pathog. 2016;12:e1005879.
    PubMed     Text format     Abstract available


  92. RAGHWANI J, Rose R, Sheridan I, Lemey P, et al
    Exceptional Heterogeneity in Viral Evolutionary Dynamics Characterises Chronic Hepatitis C Virus Infection.
    PLoS Pathog. 2016;12:e1005894.
    PubMed     Text format     Abstract available


  93. JARDINE JG, Sok D, Julien JP, Briney B, et al
    Correction: Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.
    PLoS Pathog. 2016;12:e1005905.
    PubMed     Text format     Abstract available


  94. KLASSE PJ, LaBranche CC, Ketas TJ, Ozorowski G, et al
    Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C.
    PLoS Pathog. 2016;12:e1005864.
    PubMed     Text format     Abstract available


  95. CARIAS AM, Allen SA, Fought AJ, Kotnik Halavaty K, et al
    Increases in Endogenous or Exogenous Progestins Promote Virus-Target Cell Interactions within the Non-human Primate Female Reproductive Tract.
    PLoS Pathog. 2016;12:e1005885.
    PubMed     Text format     Abstract available


  96. ZEVIN AS, Xie IY, Birse K, Arnold K, et al
    Microbiome Composition and Function Drives Wound-Healing Impairment in the Female Genital Tract.
    PLoS Pathog. 2016;12:e1005889.
    PubMed     Text format     Abstract available


  97. DA SILVA SANTOS C, Tartour K, Cimarelli A
    A Novel Entry/Uncoating Assay Reveals the Presence of at Least Two Species of Viral Capsids During Synchronized HIV-1 Infection.
    PLoS Pathog. 2016;12:e1005897.
    PubMed     Text format     Abstract available


    August 2016
  98. FENG Y, Tran K, Bale S, Kumar S, et al
    Thermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies.
    PLoS Pathog. 2016;12:e1005767.
    PubMed     Text format     Abstract available


  99. DEMERS KR, Makedonas G, Buggert M, Eller MA, et al
    Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection.
    PLoS Pathog. 2016;12:e1005805.
    PubMed     Text format     Abstract available


  100. PLOQUIN MJ, Madec Y, Casrouge A, Huot N, et al
    Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset.
    PLoS Pathog. 2016;12:e1005774.
    PubMed     Text format     Abstract available


  101. LASKEY SB, Pohlmeyer CW, Bruner KM, Siliciano RF, et al
    Evaluating Clonal Expansion of HIV-Infected Cells: Optimization of PCR Strategies to Predict Clonality.
    PLoS Pathog. 2016;12:e1005689.
    PubMed     Text format     Abstract available


  102. PINKEVYCH M, Cromer D, Tolstrup M, Grimm AJ, et al
    Correction: HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days-Implications for HIV Remission.
    PLoS Pathog. 2016;12:e1005745.
    PubMed     Text format     Abstract available


  103. PINKEVYCH M, Kent SJ, Tolstrup M, Lewin SR, et al
    Modeling of Experimental Data Supports HIV Reactivation from Latency after Treatment Interruption on Average Once Every 5-8 Days.
    PLoS Pathog. 2016;12:e1005740.
    PubMed     Text format    


  104. HILL AL, Rosenbloom DI, Siliciano JD, Siliciano RF, et al
    Insufficient Evidence for Rare Activation of Latent HIV in the Absence of Reservoir-Reducing Interventions.
    PLoS Pathog. 2016;12:e1005679.
    PubMed     Text format    


  105. JARDINE JG, Sok D, Julien JP, Briney B, et al
    Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.
    PLoS Pathog. 2016;12:e1005815.
    PubMed     Text format     Abstract available


  106. YORK A, Kutluay SB, Errando M, Bieniasz PD, et al
    The RNA Binding Specificity of Human APOBEC3 Proteins Resembles That of HIV-1 Nucleocapsid.
    PLoS Pathog. 2016;12:e1005833.
    PubMed     Text format     Abstract available


  107. BADIA R, Pujantell M, Riveira-Munoz E, Puig T, et al
    The G1/S Specific Cyclin D2 Is a Regulator of HIV-1 Restriction in Non-proliferating Cells.
    PLoS Pathog. 2016;12:e1005829.
    PubMed     Text format     Abstract available


  108. PACE M, Williams J, Kurioka A, Gerry AB, et al
    Histone Deacetylase Inhibitors Enhance CD4 T Cell Susceptibility to NK Cell Killing but Reduce NK Cell Function.
    PLoS Pathog. 2016;12:e1005782.
    PubMed     Text format     Abstract available


  109. TAY MZ, Liu P, Williams LD, McRaven MD, et al
    Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses.
    PLoS Pathog. 2016;12:e1005817.
    PubMed     Text format     Abstract available


    July 2016

  110. Correction: Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV.
    PLoS Pathog. 2016;12:e1005778.
    PubMed     Text format     Abstract available


  111. BOYD DF, Sharma A, Humes D, Cheng-Mayer C, et al
    Adapting SHIVs In Vivo Selects for Envelope-Mediated Interferon-alpha Resistance.
    PLoS Pathog. 2016;12:e1005727.
    PubMed     Text format     Abstract available


  112. RADEMEYER C, Korber B, Seaman MS, Giorgi EE, et al
    Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization.
    PLoS Pathog. 2016;12:e1005742.
    PubMed     Text format     Abstract available


  113. HOFFMANN M, Pantazis N, Martin GE, Hickling S, et al
    Exhaustion of Activated CD8 T Cells Predicts Disease Progression in Primary HIV-1 Infection.
    PLoS Pathog. 2016;12:e1005661.
    PubMed     Text format     Abstract available


  114. FROMENTIN R, Bakeman W, Lawani MB, Khoury G, et al
    CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART.
    PLoS Pathog. 2016;12:e1005761.
    PubMed     Text format     Abstract available


  115. MUIR R, Metcalf T, Tardif V, Takata H, et al
    Altered Memory Circulating T Follicular Helper-B Cell Interaction in Early Acute HIV Infection.
    PLoS Pathog. 2016;12:e1005777.
    PubMed     Text format     Abstract available


    June 2016
  116. ABDEL-MOHSEN M, Chavez L, Tandon R, Chew GM, et al
    Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation.
    PLoS Pathog. 2016;12:e1005677.
    PubMed     Text format     Abstract available


  117. LIU F, Fan X, Auclair S, Ferguson M, et al
    Sequential Dysfunction and Progressive Depletion of Candida albicans-Specific CD4 T Cell Response in HIV-1 Infection.
    PLoS Pathog. 2016;12:e1005663.
    PubMed     Text format     Abstract available


  118. BENDJENNAT M, Saffarian S
    The Race against Protease Activation Defines the Role of ESCRTs in HIV Budding.
    PLoS Pathog. 2016;12:e1005657.
    PubMed     Text format     Abstract available


  119. DHARAN A, Talley S, Tripathi A, Mamede JI, et al
    KIF5B and Nup358 Cooperatively Mediate the Nuclear Import of HIV-1 during Infection.
    PLoS Pathog. 2016;12:e1005700.
    PubMed     Text format     Abstract available


  120. FRANCIS AC, Marin M, Shi J, Aiken C, et al
    Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells.
    PLoS Pathog. 2016;12:e1005709.
    PubMed     Text format     Abstract available


  121. ARRODE-BRUSES G, Goode D, Kleinbeck K, Wilk J, et al
    A Small Molecule, Which Competes with MAdCAM-1, Activates Integrin alpha4beta7 and Fails to Prevent Mucosal Transmission of SHIV-SF162P3.
    PLoS Pathog. 2016;12:e1005720.
    PubMed     Text format     Abstract available


    May 2016
  122. TULLY DC, Ogilvie CB, Batorsky RE, Bean DJ, et al
    Differences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder Virus.
    PLoS Pathog. 2016;12:e1005619.
    PubMed     Text format     Abstract available


  123. DELVIKS-FRANKENBERRY KA, Nikolaitchik OA, Burdick RC, Gorelick RJ, et al
    Minimal Contribution of APOBEC3-Induced G-to-A Hypermutation to HIV-1 Recombination and Genetic Variation.
    PLoS Pathog. 2016;12:e1005646.
    PubMed     Text format     Abstract available


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