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Articles published in Antimicrob Agents Chemother

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Single Articles


    April 2017
  1. NAKAMURA RL, Burlingame MA, Yang S, Crosby DC, et al
    Identification and optimization of thienopyridine carboxamides as inhibitors of HIV regulatory complexes.
    Antimicrob Agents Chemother. 2017 Apr 17. pii: AAC.02366.
    PubMed     Text format     Abstract available


  2. ZHAO C, Gunawardana M, Villinger F, Baum MM, et al
    Pharmacokinetics and Preliminary Safety of Pod-Intravaginal Rings Delivering the Monoclonal Antibody VRC01-N for HIV Prophylaxis in a Macaque Model.
    Antimicrob Agents Chemother. 2017 Apr 17. pii: AAC.02465.
    PubMed     Text format     Abstract available


  3. DAS K, Martinez SE, Arnold E
    Structural Insights into HIV Reverse Transcriptase Mutations Q151M and Q151M Complex that Confer Multi-Nucleoside Drug Resistance.
    Antimicrob Agents Chemother. 2017 Apr 10. pii: AAC.00224.
    PubMed     Text format     Abstract available


    March 2017
  4. RIMAWI BH, Johnson E, Rajakumar A, Tao S, et al
    Pharmacokinetics and Placental Transfer of Elvitegravir and Dolutegravir, and Other Antiretrovirals during Pregnancy.
    Antimicrob Agents Chemother. 2017 Mar 27. pii: AAC.02213.
    PubMed     Text format     Abstract available


  5. HUBER AD, Michailidis E, Tang J, Puray-Chavez MN, et al
    3-hydroxypyrimidine-2,4-diones as novel hepatitis B virus antivirals targeting the viral ribonuclease H.
    Antimicrob Agents Chemother. 2017 Mar 20. pii: AAC.00245.
    PubMed     Text format     Abstract available


  6. MOYA B, Barcelo IM, Bhagwat S, Patel M, et al
    WCK 5107 (Zidebactam) & WCK 5153: Novel inhibitors of PBP2 showing potent "beta-lactam enhancer" activity against Pseudomonas aeruginosa, including multidrug-resistant metallo-beta-lactamase-producing high-risk clones.
    Antimicrob Agents Chemother. 2017 Mar 13. pii: AAC.02529.
    PubMed     Text format     Abstract available


  7. NIGO M, Diaz L, Carvajal LP, Tran TT, et al
    Ceftaroline-Resistant, Daptomycin-Tolerant, and Heterogeneous Vancomycin-Intermediate Methicillin-Resistant Staphylococcus aureus Causing Infective Endocarditis.
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Text format     Abstract available


    February 2017
  8. VIDYAPRAKASH E, Abrams AJ, Shafer WM, Trees DL, et al
    Whole genome sequencing of a large panel of contemporary Neisseria gonorrhoeae clinical isolates indicates that a wild-type mtrA gene is common: implications for inducible antimicrobial resistance.
    Antimicrob Agents Chemother. 2017 Feb 13. pii: AAC.00262.
    PubMed     Text format     Abstract available


  9. KOUTSOUDAKIS G, Paris de Leon A, Herrera C, Dorner M, et al
    Oligonucleotide-lipid conjugates forming G-quadruplex structures are potent and pangenotypic hepatitis C virus entry inhibitors in vitro and ex vivo.
    Antimicrob Agents Chemother. 2017 Feb 13. pii: AAC.02354.
    PubMed     Text format     Abstract available


  10. ROBERTS O, Khoo S, Owen A, Siccardi M, et al
    Interaction of Rifampicin and Darunavir/Ritonavir or Darunavir/Cobicistat In Vitro.
    Antimicrob Agents Chemother. 2017 Feb 13. pii: AAC.01776.
    PubMed     Text format     Abstract available


  11. CHOI SR, Britigan BE, Narayanasamy P
    Ga(III) Nanoparticles Inhibit Growth of Both TB and HIV and Release of IL-6 and IL-8 in Co-Infected Macrophages.
    Antimicrob Agents Chemother. 2017 Feb 6. pii: AAC.02505.
    PubMed     Text format     Abstract available


    January 2017
  12. LE VT, Le HN, Pinheiro MG, Hahn KJ, et al
    Effects of tedizolid phosphate on survival outcomes and suppression of production of staphylococcal toxins in a rabbit model of MRSA necrotizing pneumonia.
    Antimicrob Agents Chemother. 2017 Jan 30. pii: AAC.02734.
    PubMed     Text format     Abstract available


  13. DIEP BA, Hillard JJ, Le VT, Tkaczyk C, et al
    Targeting Alpha Toxin to Mitigate Its Lethal Toxicity in Ferret and Rabbit Models of Staphylococcus aureus Necrotizing Pneumonia.
    Antimicrob Agents Chemother. 2017 Jan 23. pii: AAC.02456.
    PubMed     Text format     Abstract available


  14. GOMARASCA M, Martins TF, Greune L, Hardwidge PR, et al
    Bacterial-derived cell-penetrating peptides deliver gentamicin to kill intracellular pathogens.
    Antimicrob Agents Chemother. 2017 Jan 17. pii: AAC.02545.
    PubMed     Text format     Abstract available


    December 2016
  15. GROSSMAN NT, Casadevall A
    Physiological Differences in C. neoformans in vitro versus in vivo and Their Effects on Antifungal Susceptibility.
    Antimicrob Agents Chemother. 2016 Dec 28. pii: AAC.02108.
    PubMed     Text format     Abstract available


  16. ZERBATO JM, Tachedjian G, Sluis-Cremer N
    Nonnucleoside Reverse Transcriptase Inhibitors Reduce HIV-1 Virus Production from Latently Infected Resting CD4+ T Cells Following Latency Reversal.
    Antimicrob Agents Chemother. 2016 Dec 19. pii: AAC.01736.
    PubMed     Text format     Abstract available


  17. LOMONOSOVA E, Zlotnick A, Tavis JE
    Synergistic Interactions between Hepatitis B Virus Ribonuclease H Antagonists and Other Inhibitors.
    Antimicrob Agents Chemother. 2016 Dec 12. pii: AAC.02441.
    PubMed     Text format     Abstract available


  18. FOFANA MO, Shrestha S, Knight GM, Cohen T, et al
    Role of pyrazinamide in the emergence of extensively drug-resistant tuberculosis: a multi-strain mathematical model.
    Antimicrob Agents Chemother. 2016 Dec 12. pii: AAC.00498.
    PubMed     Text format     Abstract available


  19. VALADE E, Bouazza N, Lui G, Martinez Illamola S, et al
    Population Pharmacokinetic Modeling of Tenofovir in the Male Genital Tract of HIV-infected Patients.
    Antimicrob Agents Chemother. 2016 Dec 12. pii: AAC.02062.
    PubMed     Text format     Abstract available


  20. KING JR, Khatri A, Trinh R, Viani RM, et al
    Pharmacokinetic Evaluation of Darunavir Administered Once or Twice daily in Combination with Ritonavir or the Three Direct Acting Antiviral Regimen of Ombitasvir, Paritaprevir, Ritonavir and Dasabuvir in Adults Co-infected with Hepatitis C and Human I
    Antimicrob Agents Chemother. 2016 Dec 5. pii: AAC.02135.
    PubMed     Text format     Abstract available


    November 2016
  21. FOISSAC F, Blume J, Treluyer JM, Tylleskar T, et al
    Are Prophylactic and Therapeutic Target Concentrations Different? The Case of Lopinavir/ritonavir or Lamivudine Administered to Infants for the Prevention of Mother-to-Child HIV-1 Transmission during Breastfeeding.
    Antimicrob Agents Chemother. 2016 Nov 28. pii: AAC.01869.
    PubMed     Text format     Abstract available


  22. PENROSE KJ, Wallis CL, Brumme CJ, Hamanishi KA, et al
    Frequent Cross-Resistance to Dapivirine in HIV-1 Subtype C-Infected Individuals on Failing First-Line Antiretroviral Therapy in South Africa.
    Antimicrob Agents Chemother. 2016 Nov 28. pii: AAC.01805.
    PubMed     Text format     Abstract available


  23. KHALILIEH S, Yee KL, Sanchez RI, Triantafyllou I, et al
    Results of a doravirine-atorvastatin drug-drug interaction study.
    Antimicrob Agents Chemother. 2016 Nov 21. pii: AAC.01364.
    PubMed     Text format     Abstract available


  24. YEE KL, Sanchez RI, Auger P, Liu R, et al
    An Evaluation of Doravirine Pharmacokinetics When Switching From Efavirenz to Doravirine in Healthy Subjects.
    Antimicrob Agents Chemother. 2016 Nov 21. pii: AAC.01757.
    PubMed     Text format     Abstract available


  25. PONCE CA, Chabe M, George C, Cardenas A, et al
    High prevalence of Pneumocystis jirovecii dihydropteroate synthase gene mutations in patients with first episode of Pneumocystis pneumonia in Santiago, Chile, and their clinical response to trimethoprim-sulfamethoxazole therapy.
    Antimicrob Agents Chemother. 2016 Nov 14. pii: AAC.01290.
    PubMed     Text format     Abstract available


  26. ANTWI S, Yang H, Enimil A, Sarfo AM, et al
    Pharmacokinetics of the First-line Antituberculosis Drugs in Ghanaian Children with Tuberculosis with and without HIV Coinfection.
    Antimicrob Agents Chemother. 2016 Nov 14. pii: AAC.01701.
    PubMed     Text format     Abstract available


  27. MANDAL S, Belshan M, Holec A, Zhou Y, et al
    An enhanced Emtricitabine loaded long-acting nano-formulation for prevention or treatment of HIV infection.
    Antimicrob Agents Chemother. 2016 Nov 7. pii: AAC.01475.
    PubMed     Text format     Abstract available


  28. SONOIKI E, Nsanzabana C, Legac J, Sindhe KM, et al
    Altered Plasmodium falciparum sensitivity to the antiretroviral protease inhibitor lopinavir associated with polymorphisms in pfmdr1.
    Antimicrob Agents Chemother. 2016 Nov 7. pii: AAC.01949.
    PubMed     Text format     Abstract available


    October 2016
  29. BAM RA, Hansen D, Irrinki A, Mulato A, et al
    TLR7 Agonist GS-9620 Is a Potent Inhibitor of Acute HIV-1 Infection in Human Peripheral Blood Mononuclear Cells.
    Antimicrob Agents Chemother. 2016 Oct 31. pii: AAC.01369.
    PubMed     Text format     Abstract available


  30. AOURI M, Barcelo C, Guidi M, Rotger M, et al
    Population pharmacokinetics and pharmacogenetics analysis of Rilpivirine in HIV-1 infected individuals.
    Antimicrob Agents Chemother. 2016 Oct 31. pii: AAC.00899.
    PubMed     Text format     Abstract available


  31. ROBARGE JD, Metzger IF, Lu J, Thong N, et al
    Population pharmacokinetic modeling to estimate the contribution of genetic and non-genetic factors of efavirenz disposition.
    Antimicrob Agents Chemother. 2016 Oct 31. pii: AAC.01813.
    PubMed     Text format     Abstract available


  32. SCHERRER D, Rouzier R, Cardona M, Barrett PN, et al
    Food effect on pharmacokinetic parameters of ABX464 administered orally: a randomized trial in healthy male subjects.
    Antimicrob Agents Chemother. 2016 Oct 31. pii: AAC.01288.
    PubMed     Text format     Abstract available


    September 2016
  33. TSIANG M, Jones GS, Goldsmith J, Mulato A, et al
    Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile.
    Antimicrob Agents Chemother. 2016 Sep 19. pii: AAC.01474.
    PubMed     Text format     Abstract available


  34. FENAUX M, Lin X, Yokokawa F, Sweeney Z, et al
    Anti-viral nucleotide incorporation by recombinant human mitochondrial RNA polymerase is predictive for increased in vivo mitochondrial toxicity risk.
    Antimicrob Agents Chemother. 2016 Sep 19. pii: AAC.01253.
    PubMed     Text format     Abstract available


  35. AMANO M, Salcedo-Gomez PM, Zhao R, Yedidi RS, et al
    A Modified P1 Moiety Enhances in vitro Antiviral Activity against Various Multi-Drug-Resistant HIV-1 Variants and in vitro CNS Penetration Properties of a Novel Nonpeptidic Protease Inhibitor, GRL-10413.
    Antimicrob Agents Chemother. 2016 Sep 12. pii: AAC.01428.
    PubMed     Text format     Abstract available


  36. DESTA Z, Metzger IF, Thong N, Lu JB, et al
    Inhibition of CYP2B6 Activity by Voriconazole Profiled Using Efavirenz Disposition in Healthy Volunteers.
    Antimicrob Agents Chemother. 2016 Sep 6. pii: AAC.01000.
    PubMed     Text format     Abstract available


    August 2016
  37. CASTILLO-MANCILLA J, Seifert S, Campbell K, Coleman S, et al
    Emtricitabine-Triphosphate in Dried Blood Spots as a Marker of Recent Dosing.
    Antimicrob Agents Chemother. 2016 Aug 29. pii: AAC.01017.
    PubMed     Text format     Abstract available


  38. GROOMS TN, Vuong HR, Tyo KM, Malik DA, et al
    Griffithsin-Modified Electrospun Fibers as a Delivery Scaffold to Prevent HIV Infection.
    Antimicrob Agents Chemother. 2016 Aug 22. pii: AAC.00956.
    PubMed     Text format     Abstract available


  39. DIEP BA, Le VT, Visram ZC, Rouha H, et al
    Improved protection in a rabbit model of CA-MRSA necrotizing pneumonia upon neutralization of leukocidins in addition to alpha-hemolysin.
    Antimicrob Agents Chemother. 2016 Aug 15. pii: AAC.01213.
    PubMed     Text format     Abstract available


  40. KHATRI A, Trinh R, Zhao W, Podsadecki T, et al
    Drug-Drug Interaction Between the Direct-acting Antiviral Regimen of Ombitasvir/Paritaprevir/Ritonavir Plus Dasabuvir and the HIV Antiretroviral Agents Dolutegravir or Abacavir Plus Lamivudine.
    Antimicrob Agents Chemother. 2016 Aug 8. pii: AAC.00795.
    PubMed     Text format     Abstract available


  41. ROCKWOOD NN, Meintjes G, Chirehwa M, Wiesner L, et al
    HIV-1 co-infection does not reduce exposure to rifampicin, isoniazid, and pyrazinamide in South African tuberculosis outpatients.
    Antimicrob Agents Chemother. 2016 Aug 1. pii: AAC.00480.
    PubMed     Text format     Abstract available


  42. GONZALEZ-SERNA A, Genebat M, De Luna-Romero M, Tarancon-Diez L, et al
    Validation of the HIV Tropism Test TROCAI Using the Virological Response to a Short-term Maraviroc Monotherapy Exposure.
    Antimicrob Agents Chemother. 2016 Aug 1. pii: AAC.01326.
    PubMed     Text format     Abstract available


    July 2016
  43. MARTINEZ ZS, Castro E, Seong CS, Ceron MR, et al
    Fullerene Derivatives Strongly Inhibit HIV-1 Replication by Affecting Virus Maturation without Impairing Protease Activity.
    Antimicrob Agents Chemother. 2016 Jul 18. pii: AAC.00341.
    PubMed     Text format     Abstract available


  44. LE VT, Tkaczyk C, Chau S, Rao RL, et al
    Acute bacterial skin and skin structure infection: Critical role of alpha-toxin and protective effects of its neutralization by a human antibody.
    Antimicrob Agents Chemother. 2016 Jul 11. pii: AAC.00710.
    PubMed     Text format     Abstract available


  45. CECKOVA M, Reznicek J, Ptackova Z, Cerveny L, et al
    Interaction of lamivudine with ABC and SLC transporters: role in placental transport.
    Antimicrob Agents Chemother. 2016 Jul 11. pii: AAC.00648.
    PubMed     Text format     Abstract available


  46. NOGUCHI LM, Montgomery ET, Biggio JR, Hendrix CW, et al
    Detectable tenofovir levels in breastfeeding infants of mothers exposed to topical tenofovir.
    Antimicrob Agents Chemother. 2016 Jul 11. pii: AAC.00645.
    PubMed     Text format     Abstract available


  47. LI M, Mislak AC, Foli Y, Agbosu E, et al
    DNA Polymerase-gamma R953C Mutant is Associated with ART-Induced Mitochondrial Toxicity.
    Antimicrob Agents Chemother. 2016 Jul 5. pii: AAC.00976.
    PubMed     Text format     Abstract available


  48. VILLEGAS G, Calenda G, Zhang S, Mizenina O, et al
    In vitro exposure to PC-1005 and cervicovaginal lavages from women vaginally administered PC-1005 inhibit HIV-1 and HSV-2 infection in human cervical mucosa.
    Antimicrob Agents Chemother. 2016 Jul 5. pii: AAC.00392.
    PubMed     Text format     Abstract available


    June 2016
  49. LU Y, Goti V, Chaturvedula A, Haberer JE, et al
    Population pharmacokinetics of tenofovir in HIV-1 uninfected members of sero-discordant couples and effect of dose reporting methods.
    Antimicrob Agents Chemother. 2016 Jun 27. pii: AAC.00559.
    PubMed     Text format     Abstract available


  50. CHEN X, Castillo-Mancilla JR, Seifert SM, McAllister K, et al
    Analysis of the endogenous deoxynucleoside triphosphate pool in HIV positive and negative individuals receiving tenofovir-emtricitabine.
    Antimicrob Agents Chemother. 2016 Jun 27. pii: AAC.01019.
    PubMed     Text format     Abstract available


    May 2016
  51. RIVERO-BUCETA E, Sun L, Gualda BM, Doyaguez EG, et al
    An unexpected twist: optimization of a class of tryptophan dendrimers that inhibit HIV replication leads to a selective, specific and low nanomolar inhibitor of clinical isolates of enterovirus A71.
    Antimicrob Agents Chemother. 2016 May 31. pii: AAC.00626.
    PubMed     Text format     Abstract available


  52. CUSTODIO JM, Fordyce M, Garner W, Vimal M, et al
    Pharmacokinetics and Safety of Tenofovir Alafenamide in HIV-uninfected Subjects with Severe Renal Impairment.
    Antimicrob Agents Chemother. 2016 May 23. pii: AAC.00005.
    PubMed     Text format     Abstract available


  53. VARGAS G, Vincent KL, Zhu Y, Szafron D, et al
    In vivo rectal mucosal barrier function imaging in a large animal model using confocal endomicroscopy: implications for injury assessment and use in HIV prevention studies.
    Antimicrob Agents Chemother. 2016 May 16. pii: AAC.00134.
    PubMed     Text format     Abstract available


  54. CHUNG DH, Golden JE, Adcock RS, Schroeder CE, et al
    Discovery of a broad-spectrum antiviral compound that inhibits pyrimidine biosynthesis and establishes a type 1 interferon-independent antiviral state.
    Antimicrob Agents Chemother. 2016 May 16. pii: AAC.00282.
    PubMed     Text format     Abstract available


  55. WARRILOW AG, Parker JE, Price CL, Nes WD, et al
    The Investigational Drug VT-1129 is a Highly Potent Inhibitor of Cryptococcus species CYP51 but only Weakly Inhibits the Human Enzyme.
    Antimicrob Agents Chemother. 2016 May 9. pii: AAC.00349.
    PubMed     Text format     Abstract available


  56. SRINIVASAN P, Zhang J, Martin A, Kelley K, et al
    Safety and pharmacokinetics of quick dissolving polymeric vaginal films delivering the antiretroviral IQP-0528 for pre-exposure prophylaxis.
    Antimicrob Agents Chemother. 2016 May 2. pii: AAC.00082.
    PubMed     Text format     Abstract available


    April 2016
  57. NOWICKA-SANS B, Protack T, Lin Z, Li Z, et al
    BMS-955176: Identification and Characterization of a Second-Generation HIV-1 Maturation Inhibitor with Improved Potency, Anti-viral Spectrum and Gag Polymorphic Coverage.
    Antimicrob Agents Chemother. 2016 Apr 18. pii: AAC.02560.
    PubMed     Text format     Abstract available


  58. ALSAAD N, Dijkstra JA, Akkerman OW, de Lange WC, et al
    A pharmacokinetic evaluation of sulfamethoxazole 800 mg once daily in the treatment of tuberculosis.
    Antimicrob Agents Chemother. 2016 Apr 11. pii: AAC.02175.
    PubMed     Text format     Abstract available


  59. LUO M, Chapel S, Sevinsky H, Savant I, et al
    Population Pharmacokinetics Analysis to Inform Efavirenz Dosing Recommendations in Pediatric HIV Patients Aged 3 Months to 3 Years.
    Antimicrob Agents Chemother. 2016 Apr 11. pii: AAC.02678.
    PubMed     Text format     Abstract available


  60. MOSS JA, Butkyavichene I, Churchman SA, Gunawardana M, et al
    Combination pod-intravaginal ring delivers antiretroviral agents for HIV prophylaxis: pharmacokinetic evaluation in an ovine model.
    Antimicrob Agents Chemother. 2016 Apr 11. pii: AAC.00391.
    PubMed     Text format     Abstract available


  61. DESTACHE CJ, Mandal S, Zhe Y, Kang G, et al
    Topical Tenofovir Disoproxil Fumarate (DF) Nanoparticles Prevents HIV-1 Vaginal Transmission in the Humanized Mouse Model.
    Antimicrob Agents Chemother. 2016 Apr 4. pii: AAC.00450.
    PubMed     Text format     Abstract available


    March 2016
  62. KYEYUNE F, Gibson RM, Nankya I, Venner C, et al
    Low Frequency Drug Resistance in HIV-infected Ugandans on Antiretroviral Treatment is Associated with Regimen Failure.
    Antimicrob Agents Chemother. 2016 Mar 21. pii: AAC.00038.
    PubMed     Text format     Abstract available


  63. KHATRI A, Dutta S, Dunbar M, Podsadecki T, et al
    Evaluation of Drug-Drug Interactions Between Direct-Acting Anti-Hepatitis C Virus Combination Regimens and the HIV-1 Antiretroviral Agents Raltegravir, Tenofovir, Emtricitabine, Efavirenz, and Rilpivirine.
    Antimicrob Agents Chemother. 2016 Mar 7. pii: AAC.02605.
    PubMed     Text format     Abstract available


    February 2016
  64. SWANSON R, Ammerman N, Ngcobo B, Adamson J, et al
    Clofazimine contributes sustained antimicrobial activity after treatment cessation in the mouse model of tuberculosis chemotherapy.
    Antimicrob Agents Chemother. 2016 Feb 29. pii: AAC.00177.
    PubMed     Text format     Abstract available


  65. LANDRY I, Zhu L, Abutarif M, Hruska M, et al
    Model-based Phase 3 dose selection for HIV-1 attachment inhibitor prodrug BMS-663068 in HIV-1-infected patients: population pharmacokinetics/pharmacodynamics of the active moiety, BMS-626529.
    Antimicrob Agents Chemother. 2016 Feb 22. pii: AAC.02503.
    PubMed     Text format     Abstract available


  66. DEZZUTTI CS, Else LJ, Yandura SE, Shetler C, et al
    Distinct pharmacodynamic activity of rilpivirine in ectocervical and colonic explant tissue.
    Antimicrob Agents Chemother. 2016 Feb 22. pii: AAC.00167.
    PubMed     Text format     Abstract available


  67. KIS O, Sankaran-Walters S, Hoque MT, Walmsley SL, et al
    HIV-1 Alters Intestinal Expression of Drug Transporters and Metabolic Enzymes: Implications in Antiretroviral Drug Disposition.
    Antimicrob Agents Chemother. 2016 Feb 22. pii: AAC.02278.
    PubMed     Text format     Abstract available


  68. OUEDRAOGO AS, Compain F, Sanou M, Aberkane S, et al
    First description of IncX3 plasmids carrying blaOXA-181 in Escherichia coli clinical isolates in Burkina Faso.
    Antimicrob Agents Chemother. 2016 Feb 16. pii: AAC.00147.
    PubMed     Text format     Abstract available


  69. MOLTO J, Graterol F, Miranda C, Khoo S, et al
    Removal of dolutegravir by hemodialysis in HIV-infected patients with end-stage renal disease.
    Antimicrob Agents Chemother. 2016 Feb 8. pii: AAC.03131.
    PubMed     Text format     Abstract available


  70. GIANDHARI J, Basson AE, Sutherland K, Parry CM, et al
    Contribution of Gag and Protease to HIV-1 Phenotypic Drug Resistance in Paediatric Patients Failing Protease-Inhibitor Based Therapy.
    Antimicrob Agents Chemother. 2016 Feb 1. pii: AAC.02682.
    PubMed     Text format     Abstract available


  71. VINOT C, Treluyer JM, Giraud C, Gavard L, et al
    Bidirectional transfer of RLT in the ex vivo human cotyledon perfusion model.
    Antimicrob Agents Chemother. 2016 Feb 1. pii: AAC.00007.
    PubMed     Text format     Abstract available


  72. FENG M, Sachs NA, Xu M, Grobler J, et al
    Doravirine Suppresses Common NNRTI-associated Mutants at Clinically Relevant Concentrations.
    Antimicrob Agents Chemother. 2016 Feb 1. pii: AAC.02650.
    PubMed     Text format     Abstract available


  73. RAWSON JM, Daly MB, Xie J, Clouser CL, et al
    5-azacytidine enhances the mutagenesis of HIV-1 by reduction to 5-aza-2'-deoxycytidine.
    Antimicrob Agents Chemother. 2016 Feb 1. pii: AAC.03084.
    PubMed     Text format     Abstract available


    January 2016
  74. THENIN-HOUSSIER S, de Vera IM, Pedro-Rosa L, Brady A, et al
    Ebselen, a small molecule capsid-inhibitor of HIV-1 replication.
    Antimicrob Agents Chemother. 2016 Jan 25. pii: AAC.02574.
    PubMed     Text format     Abstract available


  75. BEKKER A, Schaaf HS, Draper HR, van der Laan L, et al
    The pharmacokinetics of rifampicin, isoniazid, pyrazinamide and ethambutol in infants dosed at revised WHO-recommended treatment guidelines.
    Antimicrob Agents Chemother. 2016 Jan 25. pii: AAC.02600.
    PubMed     Text format     Abstract available


    December 2015
  76. TANEVA E, Crooker K, Park SH, Su JT, et al
    Differential Mechanisms of Tenofovir and Tenofovir Disoproxil Fumarate Cellular Transport and Implications for Topical Pre-exposure Prophylaxis.
    Antimicrob Agents Chemother. 2015 Dec 28. pii: AAC.02793.
    PubMed     Text format     Abstract available


  77. DEL PRETE GQ, Oswald K, Lara A, Shoemaker R, et al
    Elevated plasma viral loads in romidepsin treated SIV-infected rhesus macaques on suppressive combination antiretroviral therapy.
    Antimicrob Agents Chemother. 2015 Dec 28. pii: AAC.02625.
    PubMed     Text format     Abstract available


  78. NYUNT MM, Nguyen VK, Kajubi R, Huang L, et al
    Artemether-Lumefantrine Pharmacokinetics and Clinical Response is Minimally Altered in Ugandan Pregnant Women Treated for Uncomplicated Plasmodium Falciparum Malaria.
    Antimicrob Agents Chemother. 2015 Dec 14. pii: AAC.01605.
    PubMed     Text format     Abstract available


  79. PEREIRA LE, Mesquita PM, Ham A, Singletary T, et al
    Pharmacokinetic and pharmacodynamic evaluation following vaginal application of IQB3002, a dual chamber microbicide gel containing the NNRTI IQP-0528 in rhesus macaques.
    Antimicrob Agents Chemother. 2015 Dec 14. pii: AAC.02201.
    PubMed     Text format     Abstract available


  80. DENTI P, Martinson N, Cohn S, Mashabela F, et al
    Population pharmacokinetics of rifampicin in pregnant women with tuberculosis and HIV co-infection in Soweto, South Africa.
    Antimicrob Agents Chemother. 2015 Dec 7. pii: AAC.02051.
    PubMed     Text format     Abstract available


  81. ABERKANE S, Compain F, Decre D, Dupont C, et al
    High prevalence of SXT/R391-related integrative and conjugative elements carrying blaCMY-2 in Proteus mirabilis from gull isolates in the South of France.
    Antimicrob Agents Chemother. 2015 Dec 7. pii: AAC.01654.
    PubMed     Text format     Abstract available


  82. MELIS V, Usach I, Gandia P, Peris JE, et al
    Inhibition of efavirenz metabolism by sertraline and nortriptyline and their effect on the efavirenz plasma concentrations.
    Antimicrob Agents Chemother. 2015 Dec 7. pii: AAC.02129.
    PubMed     Text format     Abstract available


  83. SAID JS, Trybala E, Gorander S, Ekblad M, et al
    Cholestanol-conjugated Sulfated Oligosaccharide PG545 Disrupts Lipid Envelope of Herpes Simplex Virus Particles.
    Antimicrob Agents Chemother. 2015 Dec 7. pii: AAC.02132.
    PubMed     Text format     Abstract available


    November 2015
  84. SCOTT YM, Park SY, Dezzutti CS
    Broadly neutralizing anti-HIV antibodies prevent HIV infection of mucosal tissue ex vivo.
    Antimicrob Agents Chemother. 2015 Nov 23. pii: AAC.02097.
    PubMed     Text format     Abstract available


  85. KONG EF, Tsui C, Boyce H, Ibrahim A, et al
    Development and In vivo Evaluation of a Novel Histatin-5 Bioadhesive Hydrogel Formulation against Oral Candidiasis.
    Antimicrob Agents Chemother. 2015 Nov 23. pii: AAC.02624.
    PubMed     Text format     Abstract available


  86. ANDREATTA KN, Miller MD, White KL
    Drug Susceptibility and Viral Fitness of HIV-1 with Integrase Strand Transfer Inhibitor Resistance Substitutions Q148R or N155H in Combination with Nucleoside/nucleotide Reverse Transcriptase Inhibitor Resistance Substitutions.
    Antimicrob Agents Chemother. 2015 Nov 16. pii: AAC.02096.
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  87. XU HT, Colby-Germinario SP, Hassounah S, Quashie PK, et al
    Identification of a pyridoxine-derived small-molecule inhibitor targeting dengue virus RNA-dependent RNA polymerase.
    Antimicrob Agents Chemother. 2015 Nov 16. pii: AAC.02203.
    PubMed     Text format     Abstract available


  88. VEAZEY RS, Chatterji U, Bobardt M, Russell-Lodrigue KE, et al
    C5A Protects Macaques From a Vaginal SHIV Challenge.
    Antimicrob Agents Chemother. 2015 Nov 9. pii: AAC.01925.
    PubMed     Text format     Abstract available


  89. MISLAK AC, Anderson KS
    Insights into the Molecular Mechanism of Polymerization and NRTI Incorporation for Human PrimPol.
    Antimicrob Agents Chemother. 2015 Nov 9. pii: AAC.02270.
    PubMed     Text format     Abstract available


  90. CHIREHWA MT, Rustomjee R, Mthiyane T, Onyebujoh P, et al
    Model-based evaluation of higher doses of rifampicin using a semi-mechanistic model incorporating auto-induction and saturation of hepatic extraction.
    Antimicrob Agents Chemother. 2015 Nov 9. pii: AAC.01830.
    PubMed     Text format     Abstract available


  91. SALEM AH, Kaefer Jones A, Santini-Oliveira M, Taylor GP, et al
    No Need for Lopinavir Dose Adjustment during Pregnancy: A Population Pharmacokinetic and Exposure-Response Analysis in Pregnant and Non-Pregnant HIV Infected Subjects.
    Antimicrob Agents Chemother. 2015 Nov 2. pii: AAC.01197.
    PubMed     Text format     Abstract available


  92. KUWATA T, Enomoto I, Baba M, Matsushita S, et al
    Incompatible natures of HIV-1 envelope in resistance to the CCR5 antagonist cenicriviroc and neutralizing antibodies.
    Antimicrob Agents Chemother. 2015 Nov 2. pii: AAC.02285.
    PubMed     Text format     Abstract available


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