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Articles published in J Med Chem

Retrieve available abstracts of 16 articles:
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Single Articles


    April 2008
  1. GUTIERREZ-LUGO MT , Bewley CA
    Natural Products, Small Molecules, and Genetics in Tuberculosis Drug Development.
    J Med Chem. 2008;.
    PubMed     Related articles   


    March 2008
  2. VELAPARTHI S , Brunsteiner M, Uddin R, Wan B, et al
    5-tert-Butyl-N-pyrazol-4-yl-4,5,6,7-tetrahydrobenzo[d]isoxazole-3-carboxamide Derivatives as Novel Potent Inhibitors of Mycobacterium tuberculosis Pantothenate Synthetase: Initiating a Quest for New Antitubercular Drugs.
    J Med Chem. 2008;.
    PubMed     Related articles    Abstract available


    February 2008
  3. SIMERSKA P , Abdel-Aal AB, Fujita Y, Moyle PM, et al
    Development of a Liposaccharide-Based Delivery System and Its Application to the Design of Group A Streptococcal Vaccines.
    J Med Chem. 2008;.
    PubMed     Related articles    Abstract available


    December 2007
  4. ABDEL-AAL AB , Batzloff MR, Fujita Y, Barozzi N, et al
    Structure-Activity Relationship of a Series of Synthetic Lipopeptide Self-Adjuvanting Group A Streptococcal Vaccine Candidates.
    J Med Chem. 2007;.
    PubMed     Related articles    Abstract available


    November 2007
  5. POEL TJ , Thomas RC, Adams WJ, Aristoff PA, et al
    Antibacterial oxazolidinones possessing a novel C-5 side chain. (5R)-trans-3-[3-Fluoro-4- (1-oxotetrahydrothiopyran-4-yl)phenyl]-2- oxooxazolidine-5-carboxylic acid amide (PF-00422602), a new lead compound.
    J Med Chem. 2007;50:5886-9.
    PubMed     Related articles    Abstract available


  6. ANTHONY NG , Breen D, Clarke J, Donoghue G, et al
    Antimicrobial lexitropsins containing amide, amidine, and alkene linking groups.
    J Med Chem. 2007;50:6116-25.
    PubMed     Related articles    Abstract available


  7. METAFERIA BB , Fetterolf BJ, Shazad-Ul-Hussan S, Moravec M, et al
    Synthesis of Natural Product-Inspired Inhibitors of Mycobacterium tuberculosis Mycothiol-Associated Enzymes: The First Inhibitors of GlcNAc-Ins Deacetylase.
    J Med Chem. 2007;.
    PubMed     Related articles    Abstract available


  8. YAO B , Ji H, Cao Y, Zhou Y, et al
    Synthesis and antifungal activities of novel 2-aminotetralin derivatives.
    J Med Chem. 2007;50:5293-300.
    PubMed     Related articles    Abstract available


    October 2007
  9. RECK F , Zhou F, Eyermann CJ, Kern G, et al
    Novel substituted (pyridin-3-yl)phenyloxazolidinones: antibacterial agents with reduced activity against monoamine oxidase A and increased solubility.
    J Med Chem. 2007;50:4868-81.
    PubMed     Related articles    Abstract available


    September 2007
  10. SHILABIN AG , Kasanah N, Wedge DE, Hamann MT, et al
    Lysosome and HER3 (ErbB3) selective anticancer agent kahalalide F: semisynthetic modifications and antifungal lead-exploration studies.
    J Med Chem. 2007;50:4340-50.
    PubMed     Related articles    Abstract available


    August 2007
  11. HU X , Prehna G, Stebbins CE
    Targeting plague virulence factors: a combined machine learning method and multiple conformational virtual screening for the discovery of Yersinia protein kinase A inhibitors.
    J Med Chem. 2007;50:3980-3.
    PubMed     Related articles    Abstract available


  12. RAI D , Johar M, Srivastav NC, Manning T, et al
    Inhibition of Mycobacterium tuberculosis, Mycobacterium bovis, and Mycobacterium avium by Novel Dideoxy Nucleosides.
    J Med Chem. 2007;.
    PubMed     Related articles    Abstract available


    July 2007
  13. MAPLES KR , Wheeler C, Ip E, Plattner JJ, et al
    Novel semisynthetic derivative of antibiotic Eremomycin active against drug-resistant gram-positive pathogens including Bacillus anthracis.
    J Med Chem. 2007;50:3681-5.
    PubMed     Related articles    Abstract available


    June 2007
  14. JOHAR M , Manning T, Tse C, Desroches N, et al
    Growth Inhibition of Mycobacterium bovis, Mycobacterium tuberculosis and Mycobacterium avium In Vitro: Effect of 1-beta-d-2'-Arabinofuranosyl and 1-(2'-Deoxy-2'-fluoro-beta-d-2'-ribofuranosyl) Pyrimidine Nucleoside Analogs.
    J Med Chem. 2007;.
    PubMed     Related articles    Abstract available


    May 2007
  15. HANESSIAN S , Szychowski J, Adhikari SS, Vasquez G, et al
    Structure-based design, synthesis, and A-site rRNA cocrystal complexes of functionally novel aminoglycoside antibiotics: C2" ether analogues of paromomycin.
    J Med Chem. 2007;50:2352-69.
    PubMed     Related articles    Abstract available


    April 2007
  16. DABIDEEN DR , Cheng KF, Aljabari B, Miller EJ, et al
    Phenolic hydrazones are potent inhibitors of macrophage migration inhibitory factor proinflammatory activity and survival improving agents in sepsis.
    J Med Chem. 2007;50:1993-7.
    PubMed     Related articles    Abstract available


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