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  Bacterial Infections and Mycoses

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Articles published in Proc Natl Acad Sci U S A

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    July 2017
  1. PHAM TV, Murkin AS, Moynihan MM, Harris L, et al
    Mechanism-based inactivator of isocitrate lyases 1 and 2 from Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2017 Jul 5. pii: 201706134.
    PubMed     Text format     Abstract available


  2. VAN RAAPHORST R, Kjos M, Veening JW
    Chromosome segregation drives division site selection in Streptococcus pneumoniae.
    Proc Natl Acad Sci U S A. 2017 Jul 3. pii: 201620608.
    PubMed     Text format     Abstract available


  3. DEFRANCESCO AS, Masloboeva N, Syed AK, DeLoughery A, et al
    Genome-wide screen for genes involved in eDNA release during biofilm formation by Staphylococcus aureus.
    Proc Natl Acad Sci U S A. 2017 Jul 3. pii: 201704544.
    PubMed     Text format     Abstract available


    June 2017
  4. KALIA NP, Hasenoehrl EJ, Ab Rahman NB, Koh VH, et al
    Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection.
    Proc Natl Acad Sci U S A. 2017 Jun 26. pii: 201706139.
    PubMed     Text format     Abstract available


  5. WANG Y, Cheng LI, Helfer DR, Ashbaugh AG, et al
    Mouse model of hematogenous implant-related Staphylococcus aureus biofilm infection reveals therapeutic targets.
    Proc Natl Acad Sci U S A. 2017 Jun 12. pii: 201703427.
    PubMed     Text format     Abstract available


    May 2017
  6. LIU NN, Flanagan PR, Zeng J, Jani NM, et al
    Phosphate is the third nutrient monitored by TOR in Candida albicans and provides a target for fungal-specific indirect TOR inhibition.
    Proc Natl Acad Sci U S A. 2017 May 31. pii: 201617799.
    PubMed     Text format     Abstract available


  7. SAITO K, Warrier T, Somersan-Karakaya S, Kaminski L, et al
    Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations.
    Proc Natl Acad Sci U S A. 2017 May 30. pii: 201705385.
    PubMed     Text format     Abstract available


  8. LARSON TR, Yother J
    Streptococcus pneumoniae capsular polysaccharide is linked to peptidoglycan via a direct glycosidic bond to beta-D-N-acetylglucosamine.
    Proc Natl Acad Sci U S A. 2017 May 11. pii: 201620431.
    PubMed     Text format     Abstract available


    April 2017
  9. CARBONI F, Adamo R, Fabbrini M, De Ricco R, et al
    Structure of a protective epitope of group B Streptococcus type III capsular polysaccharide.
    Proc Natl Acad Sci U S A. 2017 Apr 24. pii: 201701885.
    PubMed     Text format     Abstract available


  10. LI H, Wang XX, Wang B, Fu L, et al
    Latently and uninfected healthcare workers exposed to TB make protective antibodies against Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2017 Apr 24. pii: 201611776.
    PubMed     Text format     Abstract available


  11. RAZ A, Serrano A, Lawson C, Thaker M, et al
    Lysibodies are IgG Fc fusions with lysin binding domains targeting Staphylococcus aureus wall carbohydrates for effective phagocytosis.
    Proc Natl Acad Sci U S A. 2017 Apr 20. pii: 201619249.
    PubMed     Text format     Abstract available


  12. GRAHAM CE, Cruz MR, Garsin DA, Lorenz MC, et al
    Enterococcus faecalis bacteriocin EntV inhibits hyphal morphogenesis, biofilm formation, and virulence of Candida albicans.
    Proc Natl Acad Sci U S A. 2017 Apr 10. pii: 201620432.
    PubMed     Text format     Abstract available


  13. VILCHEZE C, Hartman T, Weinrick B, Jain P, et al
    Enhanced respiration prevents drug tolerance and drug resistance in Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2017 Apr 10. pii: 201704376.
    PubMed     Text format     Abstract available


    March 2017
  14. LIU C, Zhao Z, Fan J, Lyon CJ, et al
    Quantification of circulating Mycobacterium tuberculosis antigen peptides allows rapid diagnosis of active disease and treatment monitoring.
    Proc Natl Acad Sci U S A. 2017 Mar 27. pii: 201621360.
    PubMed     Text format     Abstract available


  15. BELJANTSEVA J, Kudrin P, Andresen L, Shingler V, et al
    Negative allosteric regulation of Enterococcus faecalis small alarmone synthetase RelQ by single-stranded RNA.
    Proc Natl Acad Sci U S A. 2017 Mar 20. pii: 201617868.
    PubMed     Text format     Abstract available


  16. FEUILLIE C, Formosa-Dague C, Hays LM, Vervaeck O, et al
    Molecular interactions and inhibition of the staphylococcal biofilm-forming protein SdrC.
    Proc Natl Acad Sci U S A. 2017 Mar 20. pii: 201616805.
    PubMed     Text format     Abstract available


  17. PUCKETT S, Trujillo C, Wang Z, Eoh H, et al
    Glyoxylate detoxification is an essential function of malate synthase required for carbon assimilation in Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2017 Mar 6. pii: 201617655.
    PubMed     Text format     Abstract available


    January 2017
  18. TROEGELER A, Mercier I, Cougoule C, Pietretti D, et al
    C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells.
    Proc Natl Acad Sci U S A. 2017 Jan 9. pii: 201613254.
    PubMed     Text format     Abstract available


    November 2016
  19. ELDHOLM V, Pettersson JH, Brynildsrud OB, Kitchen A, et al
    Armed conflict and population displacement as drivers of the evolution and dispersal of Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2016 Nov 21. pii: 201611283.
    PubMed     Text format     Abstract available


  20. LUPOLI TJ, Fay A, Adura C, Glickman MS, et al
    Reconstitution of a Mycobacterium tuberculosis proteostasis network highlights essential cofactor interactions with chaperone DnaK.
    Proc Natl Acad Sci U S A. 2016 Nov 21. pii: 201617644.
    PubMed     Text format     Abstract available


  21. SOUTTER HH, Centrella P, Clark MA, Cuozzo JW, et al
    Discovery of cofactor-specific, bactericidal Mycobacterium tuberculosis InhA inhibitors using DNA-encoded library technology.
    Proc Natl Acad Sci U S A. 2016 Nov 18. pii: 201610978.
    PubMed     Text format     Abstract available


  22. MUSYOKI AM, Shi Z, Xuan C, Lu G, et al
    Structural and functional analysis of an anchorless fibronectin-binding protein FBPS from Gram-positive bacterium Streptococcus suis.
    Proc Natl Acad Sci U S A. 2016 Nov 10. pii: 201608406.
    PubMed     Text format     Abstract available


    September 2016
  23. ROTHCHILD AC, Sissons JR, Shafiani S, Plaisier C, et al
    MiR-155-regulated molecular network orchestrates cell fate in the innate and adaptive immune response to Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2016 Sep 28. pii: 201608255.
    PubMed     Text format     Abstract available


  24. FOREMAN TW, Mehra S, LoBato DN, Malek A, et al
    CD4+ T-cell-independent mechanisms suppress reactivation of latent tuberculosis in a macaque model of HIV coinfection.
    Proc Natl Acad Sci U S A. 2016 Sep 6. pii: 201611987.
    PubMed     Text format     Abstract available


    August 2016
  25. BORITSCH EC, Khanna V, Pawlik A, Honore N, et al
    Key experimental evidence of chromosomal DNA transfer among selected tuberculosis-causing mycobacteria.
    Proc Natl Acad Sci U S A. 2016 Aug 15. pii: 201604921.
    PubMed     Text format     Abstract available


  26. STEWART CM, Buffalo CZ, Valderrama JA, Henningham A, et al
    Coiled-coil destabilizing residues in the group A Streptococcus M1 protein are required for functional interaction.
    Proc Natl Acad Sci U S A. 2016 Aug 10. pii: 201606160.
    PubMed     Text format     Abstract available


    July 2016
  27. CHISHOLM RH, Trauer JM, Curnoe D, Tanaka MM, et al
    Controlled fire use in early humans might have triggered the evolutionary emergence of tuberculosis.
    Proc Natl Acad Sci U S A. 2016 Jul 25. pii: 201603224.
    PubMed     Text format     Abstract available


  28. WARRIER T, Kapilashrami K, Argyrou A, Ioerger TR, et al
    N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis.
    Proc Natl Acad Sci U S A. 2016 Jul 18. pii: 201606590.
    PubMed     Text format     Abstract available


    June 2016
  29. KASBEKAR M, Fischer G, Mott BT, Yasgar A, et al
    Selective small molecule inhibitor of the Mycobacterium tuberculosis fumarate hydratase reveals an allosteric regulatory site.
    Proc Natl Acad Sci U S A. 2016 Jun 20. pii: 201600630.
    PubMed     Text format     Abstract available


  30. BOSI E, Monk JM, Aziz RK, Fondi M, et al
    Comparative genome-scale modelling of Staphylococcus aureus strains identifies strain-specific metabolic capabilities linked to pathogenicity.
    Proc Natl Acad Sci U S A. 2016 Jun 10. pii: 201523199.
    PubMed     Text format     Abstract available


    May 2016
  31. HUBBARD TP, Chao MC, Abel S, Blondel CJ, et al
    Genetic analysis of Vibrio parahaemolyticus intestinal colonization.
    Proc Natl Acad Sci U S A. 2016;113:6283-8.
    PubMed     Text format     Abstract available


  32. QUEREDA JJ, Dussurget O, Nahori MA, Ghozlane A, et al
    Bacteriocin from epidemic Listeria strains alters the host intestinal microbiota to favor infection.
    Proc Natl Acad Sci U S A. 2016;113:5706-11.
    PubMed     Text format     Abstract available


  33. DAS S, Lindemann C, Young BC, Muller J, et al
    Natural mutations in a Staphylococcus aureus virulence regulator attenuate cytotoxicity but permit bacteremia and abscess formation.
    Proc Natl Acad Sci U S A. 2016 May 16. pii: 201520255.
    PubMed     Text format     Abstract available


    April 2016
  34. WYNN JL, Wilson CS, Hawiger J, Scumpia PO, et al
    Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18.
    Proc Natl Acad Sci U S A. 2016 Apr 25. pii: 201515793.
    PubMed     Text format     Abstract available


  35. GURUNG P, Burton A, Kanneganti TD
    NLRP3 inflammasome plays a redundant role with caspase 8 to promote IL-1beta-mediated osteomyelitis.
    Proc Natl Acad Sci U S A. 2016;113:4452-7.
    PubMed     Text format     Abstract available


  36. BROOK M, Tomlinson GH, Miles K, Smith RW, et al
    Neutrophil-derived alpha defensins control inflammation by inhibiting macrophage mRNA translation.
    Proc Natl Acad Sci U S A. 2016;113:4350-5.
    PubMed     Text format     Abstract available


  37. SCHAFFER JN, Norsworthy AN, Sun TT, Pearson MM, et al
    Proteus mirabilis fimbriae- and urease-dependent clusters assemble in an extracellular niche to initiate bladder stone formation.
    Proc Natl Acad Sci U S A. 2016;113:4494-9.
    PubMed     Text format     Abstract available


  38. GEOGHEGAN JL, Senior AM, Di Giallonardo F, Holmes EC, et al
    Virological factors that increase the transmissibility of emerging human viruses.
    Proc Natl Acad Sci U S A. 2016;113:4170-5.
    PubMed     Text format     Abstract available


  39. MAKANGA B, Yangari P, Rahola N, Rougeron V, et al
    Ape malaria transmission and potential for ape-to-human transfers in Africa.
    Proc Natl Acad Sci U S A. 2016 Apr 11. pii: 201603008.
    PubMed     Text format     Abstract available


  40. WONG GC
    Three-dimensional architecture of Vibrio cholera biofilms.
    Proc Natl Acad Sci U S A. 2016;113:3711-3.
    PubMed     Text format    


  41. MATSUI T, Nambu S, Goulding CW, Takahashi S, et al
    Unique coupling of mono- and dioxygenase chemistries in a single active site promotes heme degradation.
    Proc Natl Acad Sci U S A. 2016;113:3779-84.
    PubMed     Text format     Abstract available


    February 2016
  42. LIU L, Lu Y, Martinez J, Bi Y, et al
    Proinflammatory signal suppresses proliferation and shifts macrophage metabolism from Myc-dependent to HIF1alpha-dependent.
    Proc Natl Acad Sci U S A. 2016;113:1564-9.
    PubMed     Text format     Abstract available


    January 2016
  43. PONNUSAMY D, Kozlova EV, Sha J, Erova TE, et al
    Cross-talk among flesh-eating Aeromonas hydrophila strains in mixed infection leading to necrotizing fasciitis.
    Proc Natl Acad Sci U S A. 2016;113:722-7.
    PubMed     Text format     Abstract available


  44. KOPF SH, Sessions AL, Cowley ES, Reyes C, et al
    Trace incorporation of heavy water reveals slow and heterogeneous pathogen growth rates in cystic fibrosis sputum.
    Proc Natl Acad Sci U S A. 2016;113:E110-6.
    PubMed     Text format     Abstract available


  45. DIEULIIS D, Johnson KR, Morse SS, Schindel DE, et al
    Opinion: Specimen collections should have a much bigger role in infectious disease research and response.
    Proc Natl Acad Sci U S A. 2016;113:4-7.
    PubMed     Text format    


    November 2015
  46. CASANOVA JL
    Human genetic basis of interindividual variability in the course of infection.
    Proc Natl Acad Sci U S A. 2015 Nov 30. pii: 201521644.
    PubMed     Text format     Abstract available


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