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  Leukemia

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Articles published in PLoS One

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    January 2017
  1. MACANAS-PIRARD P, Quezada T, Navarrete L, Broekhuizen R, et al
    The CCL2/CCR2 Axis Affects Transmigration and Proliferation but Not Resistance to Chemotherapy of Acute Myeloid Leukemia Cells.
    PLoS One. 2017;12:e0168888.
    PubMed     Text format     Abstract available


  2. MIN C, Moore N, Shearstone JR, Quayle SN, et al
    Selective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia.
    PLoS One. 2017;12:e0169128.
    PubMed     Text format     Abstract available


  3. KREIS C, Lupatsch JE, Niggli F, Egger M, et al
    Space-Time Clustering of Childhood Leukemia: Evidence of an Association with ETV6-RUNX1 (TEL-AML1) Fusion.
    PLoS One. 2017;12:e0170020.
    PubMed     Text format     Abstract available


  4. YUAN C, Chu CC, Yan XJ, Bagnara D, et al
    The Number of Overlapping AID Hotspots in Germline IGHV Genes Is Inversely Correlated with Mutation Frequency in Chronic Lymphocytic Leukemia.
    PLoS One. 2017;12:e0167602.
    PubMed     Text format     Abstract available


  5. YANG L, Sun H, Cao Y, Xuan B, et al
    GATA2 Inhibition Sensitizes Acute Myeloid Leukemia Cells to Chemotherapy.
    PLoS One. 2017;12:e0170630.
    PubMed     Text format     Abstract available


  6. NAGEL S, Pommerenke C, Scherr M, Meyer C, et al
    NKL homeobox gene activities in hematopoietic stem cells, T-cell development and T-cell leukemia.
    PLoS One. 2017;12:e0171164.
    PubMed     Text format     Abstract available


  7. EL MISSIRY M, Hjorth-Hansen H, Richter J, Olson-Stromberg U, et al
    Early BCR-ABL1 Transcript Decline after 1 Month of Tyrosine Kinase Inhibitor Therapy as an Indicator for Treatment Response in Chronic Myeloid Leukemia.
    PLoS One. 2017;12:e0171041.
    PubMed     Text format     Abstract available


  8. SHOU LH, Cao D, Dong XH, Fang Q, et al
    Prognostic significance of SETBP1 mutations in myelodysplastic syndromes, chronic myelomonocytic leukemia, and chronic neutrophilic leukemia: A meta-analysis.
    PLoS One. 2017;12:e0171608.
    PubMed     Text format     Abstract available


  9. STEFANKO A, Thiede C, Ehninger G, Simons K, et al
    Lipidomic approach for stratification of acute myeloid leukemia patients.
    PLoS One. 2017;12:e0168781.
    PubMed     Text format     Abstract available


  10. MINAGAWA K, Jamil MO, Al-Obaidi M, Pereboeva L, et al
    Correction: In Vitro Pre-Clinical Validation of Suicide Gene Modified Anti-CD33 Redirected Chimeric Antigen Receptor T-Cells for Acute Myeloid Leukemia.
    PLoS One. 2017;12:e0172640.
    PubMed     Text format     Abstract available


  11. KO PS, Liu YC, Yeh CM, Gau JP, et al
    The uniqueness of morphological features of pure erythroid leukemia in myeloid neoplasm with erythroid predominance: A reassessment using criteria revised in the 2016 World Health Organization classification.
    PLoS One. 2017;12:e0172029.
    PubMed     Text format     Abstract available


  12. LI Y, Liu S, Wang H, Mai H, et al
    Methylation level of CpG islands in GGH gene promoter in pediatric acute leukemia.
    PLoS One. 2017;12:e0173472.
    PubMed     Text format     Abstract available


  13. GARCIA-GUTIERREZ V, Gomez-Casares MT, Puerta JM, Alonso-Dominguez JM, et al
    A BCR-ABL1 cutoff of 1.5% at 3 months, determined by the GeneXpert system, predicts an optimal response in patients with chronic myeloid leukemia.
    PLoS One. 2017;12:e0173532.
    PubMed     Text format     Abstract available


  14. LIN TY, Chen KC, Liu HE, Liu AJ, et al
    Correction: MicroRNA-1301-Mediated RanGAP1 Downregulation Induces BCR-ABL Nuclear Entrapment to Enhance Imatinib Efficacy in Chronic Myeloid Leukemia Cells.
    PLoS One. 2017;12:e0173828.
    PubMed     Text format     Abstract available


  15. HOCK BD, MacPherson SA, McKenzie JL
    Idelalisib and caffeine reduce suppression of T cell responses mediated by activated chronic lymphocytic leukemia cells.
    PLoS One. 2017;12:e0172858.
    PubMed     Text format     Abstract available


  16. RAUZAN M, Chuah CT, Ko TK, Ong ST, et al
    The HDAC inhibitor SB939 overcomes resistance to BCR-ABL kinase Inhibitors conferred by the BIM deletion polymorphism in chronic myeloid leukemia.
    PLoS One. 2017;12:e0174107.
    PubMed     Text format     Abstract available


  17. SALZBERG AC, Harris-Becker A, Popova EY, Keasey N, et al
    Genome-wide mapping of histone H3K9me2 in acute myeloid leukemia reveals large chromosomal domains associated with massive gene silencing and sites of genome instability.
    PLoS One. 2017;12:e0173723.
    PubMed     Text format     Abstract available


  18. YANG L, Sun H, Cao Y, Xuan B, et al
    Correction: GATA2 Inhibition Sensitizes Acute Myeloid Leukemia Cells to Chemotherapy.
    PLoS One. 2017;12:e0175005.
    PubMed     Text format     Abstract available


  19. LAJOIE M, Drouin S, Caron M, St-Onge P, et al
    Specific expression of novel long non-coding RNAs in high-hyperdiploid childhood acute lymphoblastic leukemia.
    PLoS One. 2017;12:e0174124.
    PubMed     Text format     Abstract available


  20. JABO B, Morgan JW, Martinez ME, Ghamsary M, et al
    Sociodemographic disparities in chemotherapy and hematopoietic cell transplantation utilization among adult acute lymphoblastic and acute myeloid leukemia patients.
    PLoS One. 2017;12:e0174760.
    PubMed     Text format     Abstract available


  21. KALLEMEIJN MJ, de Ridder D, Schilperoord-Vermeulen J, van der Klift MY, et al
    Dysregulated signaling, proliferation and apoptosis impact on the pathogenesis of TCRgammadelta+ T cell large granular lymphocyte leukemia.
    PLoS One. 2017;12:e0175670.
    PubMed     Text format     Abstract available


  22. TSUNAKA M, Shinki H, Koyama T
    Cell-based evaluation of changes in coagulation activity induced by antineoplastic drugs for the treatment of acute myeloid leukemia.
    PLoS One. 2017;12:e0175765.
    PubMed     Text format     Abstract available


  23. YE X, Torabi M, Lix LM, Mahmud SM, et al
    Time and spatial trends in lymphoid leukemia and lymphoma incidence and survival among children and adolescents in Manitoba, Canada: 1984-2013.
    PLoS One. 2017;12:e0175701.
    PubMed     Text format     Abstract available


  24. NISHIMORI A, Konnai S, Okagawa T, Maekawa N, et al
    In vitro and in vivo antivirus activity of an anti-programmed death-ligand 1 (PD-L1) rat-bovine chimeric antibody against bovine leukemia virus infection.
    PLoS One. 2017;12:e0174916.
    PubMed     Text format     Abstract available


  25. GUTIERREZ-CAMINO A, Martin-Guerrero I, Garcia de Andoin N, Sastre A, et al
    Confirmation of involvement of new variants at CDKN2A/B in pediatric acute lymphoblastic leukemia susceptibility in the Spanish population.
    PLoS One. 2017;12:e0177421.
    PubMed     Text format     Abstract available


  26. MONDEJAR R, Perez C, Onaindia A, Martinez N, et al
    Molecular basis of targeted therapy in T/NK-cell lymphoma/leukemia: A comprehensive genomic and immunohistochemical analysis of a panel of 33 cell lines.
    PLoS One. 2017;12:e0177524.
    PubMed     Text format     Abstract available


  27. KARATHEDATH S, Rajamani BM, Musheer Aalam SM, Abraham A, et al
    Role of NF-E2 related factor 2 (Nrf2) on chemotherapy resistance in acute myeloid leukemia (AML) and the effect of pharmacological inhibition of Nrf2.
    PLoS One. 2017;12:e0177227.
    PubMed     Text format     Abstract available


  28. ALEXANDER PM, Caudell DL, Kucera GL, Pladna KM, et al
    The novel phospholipid mimetic KPC34 is highly active against preclinical models of Philadelphia chromosome positive acute lymphoblastic leukemia.
    PLoS One. 2017;12:e0179798.
    PubMed     Text format     Abstract available


  29. BUEHRING GC, Shen H, Schwartz DA, Lawson JS, et al
    Bovine leukemia virus linked to breast cancer in Australian women and identified before breast cancer development.
    PLoS One. 2017;12:e0179367.
    PubMed     Text format     Abstract available


  30. DOS SANTOS PC, Panero J, Stanganelli C, Palau Nagore V, et al
    Dysregulation of H/ACA ribonucleoprotein components in chronic lymphocytic leukemia.
    PLoS One. 2017;12:e0179883.
    PubMed     Text format     Abstract available


  31. WINKLER MT, Bushey RT, Gottlin EB, Campa MJ, et al
    Enhanced CDC of B cell chronic lymphocytic leukemia cells mediated by rituximab combined with a novel anti-complement factor H antibody.
    PLoS One. 2017;12:e0179841.
    PubMed     Text format     Abstract available


  32. GU R, Wei H, Wang Y, Lin D, et al
    The number of CD34+CD38+CD117+HLA-DR+CD13+CD33+ cells indicates post-chemotherapy hematopoietic recovery in patients with acute myeloid leukemia.
    PLoS One. 2017;12:e0180624.
    PubMed     Text format     Abstract available


  33. WOYWOD C, Gruber FX, Engh RA, Fla T, et al
    Dynamical models of mutated chronic myelogenous leukemia cells for a post-imatinib treatment scenario: Response to dasatinib or nilotinib therapy.
    PLoS One. 2017;12:e0179700.
    PubMed     Text format     Abstract available


  34. ALONSO-DOMINGUEZ JM, Casado LF, Anguita E, Gomez-Casares MT, et al
    PTCH1 is a reliable marker for predicting imatinib response in chronic myeloid leukemia patients in chronic phase.
    PLoS One. 2017;12:e0181366.
    PubMed     Text format     Abstract available


  35. BANDYOPADHYAY S, Li J, Traer E, Tyner JW, et al
    Cholesterol esterification inhibition and imatinib treatment synergistically inhibit growth of BCR-ABL mutation-independent resistant chronic myelogenous leukemia.
    PLoS One. 2017;12:e0179558.
    PubMed     Text format     Abstract available


  36. MCKENZIE LM, Allshouse WB, Byers TE, Bedrick EJ, et al
    Childhood hematologic cancer and residential proximity to oil and gas development.
    PLoS One. 2017;12:e0170423.
    PubMed     Text format     Abstract available


  37. ARCHER NP, Perez-Andreu V, Stoltze U, Scheurer ME, et al
    Family-based exome-wide association study of childhood acute lymphoblastic leukemia among Hispanics confirms role of ARID5B in susceptibility.
    PLoS One. 2017;12:e0180488.
    PubMed     Text format     Abstract available


  38. MARCEL V, Catez F, Berger CM, Perrial E, et al
    Expression Profiling of Ribosome Biogenesis Factors Reveals Nucleolin as a Novel Potential Marker to Predict Outcome in AML Patients.
    PLoS One. 2017;12:e0170160.
    PubMed     Text format     Abstract available


  39. MITSUHASHI Y, Furusawa Y, Aradate T, Zhao QL, et al
    3-O-trans-p-coumaroyl-alphitolic acid, a triterpenoid from Zizyphus jujuba, leads to apoptotic cell death in human leukemia cells through reactive oxygen species production and activation of the unfolded protein response.
    PLoS One. 2017;12:e0183712.
    PubMed     Text format     Abstract available


  40. SETHI MK, Thol F, Stadler M, Heuser M, et al
    VH1 Family Immunoglobulin Repertoire Sequencing after Allogeneic Hematopoietic Stem Cell Transplantation.
    PLoS One. 2017;12:e0168096.
    PubMed     Text format     Abstract available


  41. ALSOUS M, Abu Farha R, Alefishat E, Al Omar S, et al
    Adherence to 6-Mercaptopurine in children and adolescents with Acute Lymphoblastic Leukemia.
    PLoS One. 2017;12:e0183119.
    PubMed     Text format     Abstract available


  42. BRODSKA B, Kracmarova M, Holoubek A, Kuzelova K, et al
    Localization of AML-related nucleophosmin mutant depends on its subtype and is highly affected by its interaction with wild-type NPM.
    PLoS One. 2017;12:e0175175.
    PubMed     Text format     Abstract available


  43. BANJAR H, Ranasinghe D, Brown F, Adelson D, et al
    Modelling Predictors of Molecular Response to Frontline Imatinib for Patients with Chronic Myeloid Leukaemia.
    PLoS One. 2017;12:e0168947.
    PubMed     Text format     Abstract available


  44. LAVROV AV, Ustaeva OA, Adilgereeva EP, Smirnikhina SA, et al
    Copy number variation analysis in cytochromes and glutathione S-transferases may predict efficacy of tyrosine kinase inhibitors in chronic myeloid leukemia.
    PLoS One. 2017;12:e0182901.
    PubMed     Text format     Abstract available


  45. WANG Y, Yin Y, Lan X, Ye F, et al
    Molecular characterization, expression of chicken TBK1 gene and its effect on IRF3 signaling pathway.
    PLoS One. 2017;12:e0177608.
    PubMed     Text format     Abstract available


  46. FUCHS H, Rossmann N, Schmid MB, Hoenig M, et al
    Permissive hypercapnia for severe acute respiratory distress syndrome in immunocompromised children: A single center experience.
    PLoS One. 2017;12:e0179974.
    PubMed     Text format     Abstract available


  47. BELVISO S, Iuliano R, Amato R, Perrotti N, et al
    The human asparaginase enzyme (ASPG) inhibits growth in leukemic cells.
    PLoS One. 2017;12:e0178174.
    PubMed     Text format     Abstract available


  48. ISAEVSKA E, Manasievska M, Alessi D, Mosso ML, et al
    Cancer incidence rates and trends among children and adolescents in Piedmont, 1967-2011.
    PLoS One. 2017;12:e0181805.
    PubMed     Text format     Abstract available


  49. FATEHCHAND K, Santhanam R, Shen B, Erickson EL, et al
    Active hexose-correlated compound enhances extrinsic-pathway-mediated apoptosis of Acute Myeloid Leukemic cells.
    PLoS One. 2017;12:e0181729.
    PubMed     Text format     Abstract available


  50. PRABHU KS, Siveen KS, Kuttikrishnan S, Iskandarani A, et al
    Targeting of X-linked inhibitor of apoptosis protein and PI3-kinase/AKT signaling by embelin suppresses growth of leukemic cells.
    PLoS One. 2017;12:e0180895.
    PubMed     Text format     Abstract available


  51. LEE CH, Lin JC, Ho CL, Sun M, et al
    Efficacy and safety of micafungin versus extensive azoles in the prevention and treatment of invasive fungal infections for neutropenia patients with hematological malignancies: A meta-analysis of randomized controlled trials.
    PLoS One. 2017;12:e0180050.
    PubMed     Text format     Abstract available


  52. GORDIIENKO I, Shlapatska L, Kholodniuk V, Sklyarenko L, et al
    The interplay of CD150 and CD180 receptor pathways contribute to the pathobiology of chronic lymphocytic leukemia B cells by selective inhibition of Akt and MAPK signaling.
    PLoS One. 2017;12:e0185940.
    PubMed     Text format     Abstract available


  53. LATHAM S, Hughes E, Budgen B, Mechinaud F, et al
    Sources of error in measurement of minimal residual disease in childhood acute lymphoblastic leukemia.
    PLoS One. 2017;12:e0185556.
    PubMed     Text format     Abstract available


  54. CHOI SH, Severson E, Pear WS, Liu XS, et al
    The common oncogenomic program of NOTCH1 and NOTCH3 signaling in T-cell acute lymphoblastic leukemia.
    PLoS One. 2017;12:e0185762.
    PubMed     Text format     Abstract available


  55. WONG SM, Liu FH, Lee YL, Huang HM, et al
    Correction: MPT0B169, a New Antitubulin Agent, Inhibits Bcr-Abl Expression and Induces Mitochondrion-Mediated Apoptosis in Nonresistant and Imatinib-Resistant Chronic Myeloid Leukemia Cells.
    PLoS One. 2017;12:e0186531.
    PubMed     Text format     Abstract available


  56. LEE YL, Chen CW, Liu FH, Huang YW, et al
    Correction: Aclacinomycin A Sensitizes K562 Chronic Myeloid Leukemia Cells to Imatinib through p38MAPK-Mediated Erythroid Differentiation.
    PLoS One. 2017;12:e0186528.
    PubMed     Text format     Abstract available


  57. BUTI M, Manzano ML, Morillas RM, Garcia-Retortillo M, et al
    Randomized prospective study evaluating tenofovir disoproxil fumarate prophylaxis against hepatitis B virus reactivation in anti-HBc-positive patients with rituximab-based regimens to treat hematologic malignancies: The Preblin study.
    PLoS One. 2017;12:e0184550.
    PubMed     Text format     Abstract available


  58. WEIR MC, Hellwig S, Tan L, Liu Y, et al
    Dual inhibition of Fes and Flt3 tyrosine kinases potently inhibits Flt3-ITD+ AML cell growth.
    PLoS One. 2017;12:e0181178.
    PubMed     Text format     Abstract available


  59. LI S, Jin X, Wu H, Wang Y, et al
    HA117 endows HL60 cells with a stem-like signature by inhibiting the degradation of DNMT1 via its ability to down-regulate expression of the GGL domain of RGS6.
    PLoS One. 2017;12:e0180142.
    PubMed     Text format     Abstract available


  60. TAVERNA L, Tremolada M, Bonichini S, Tosetto B, et al
    Motor skill delays in pre-school children with leukemia one year after treatment: Hematopoietic stem cell transplantation therapy as an important risk factor.
    PLoS One. 2017;12:e0186787.
    PubMed     Text format     Abstract available


  61. ZHANG P, Zhao X, Zhang W, He A, et al
    Leukemia-associated gene MLAA-34 reduces arsenic trioxide-induced apoptosis in HeLa cells via activation of the Wnt/beta-catenin signaling pathway.
    PLoS One. 2017;12:e0186868.
    PubMed     Text format     Abstract available


  62. ASKMYR M, von Palffy S, Hansen N, Landberg N, et al
    Transgenic expression of human cytokines in immunodeficient mice does not facilitate myeloid expansion of BCR-ABL1 transduced human cord blood cells.
    PLoS One. 2017;12:e0186035.
    PubMed     Text format     Abstract available


  63. MEHANNA P, Gagne V, Lajoie M, Spinella JF, et al
    Characterization of the microDNA through the response to chemotherapeutics in lymphoblastoid cell lines.
    PLoS One. 2017;12:e0184365.
    PubMed     Text format     Abstract available


  64. CHABER R, Gurgul A, Wrobel G, Haus O, et al
    Whole-genome DNA methylation characteristics in pediatric precursor B cell acute lymphoblastic leukemia (BCP ALL).
    PLoS One. 2017;12:e0187422.
    PubMed     Text format     Abstract available


  65. MIN H, Niu M, Zhang W, Yan J, et al
    Emodin reverses leukemia multidrug resistance by competitive inhibition and downregulation of P-glycoprotein.
    PLoS One. 2017;12:e0187971.
    PubMed     Text format     Abstract available


  66. DUCHARTRE Y, Bachl S, Kim HN, Gang EJ, et al
    Effects of CD49d-targeted antisense-oligonucleotide on alpha4 integrin expression and function of acute lymphoblastic leukemia cells: Results of in vitro and in vivo studies.
    PLoS One. 2017;12:e0187684.
    PubMed     Text format     Abstract available


    January 2016
  67. SOMINTARA S, Leardkamolkarn V, Suttiarporn P, Mahatheeranont S, et al
    Anti-Tumor and Immune Enhancing Activities of Rice Bran Gramisterol on Acute Myelogenous Leukemia.
    PLoS One. 2016;11:e0146869.
    PubMed     Text format     Abstract available


  68. CHEN W, Xie H, Wang H, Chen L, et al
    Prognostic Significance of KIT Mutations in Core-Binding Factor Acute Myeloid Leukemia: A Systematic Review and Meta-Analysis.
    PLoS One. 2016;11:e0146614.
    PubMed     Text format     Abstract available


  69. WONG SM, Liu FH, Lee YL, Huang HM, et al
    MPT0B169, a New Antitubulin Agent, Inhibits Bcr-Abl Expression and Induces Mitochondrion-Mediated Apoptosis in Nonresistant and Imatinib-Resistant Chronic Myeloid Leukemia Cells.
    PLoS One. 2016;11:e0148093.
    PubMed     Text format     Abstract available


  70. ZHANG Y, Wu S, Luo D, Zhou J, et al
    Addition of Arsenic Trioxide into Induction Regimens Could Not Accelerate Recovery of Abnormality of Coagulation and Fibrinolysis in Patients with Acute Promyelocytic Leukemia.
    PLoS One. 2016;11:e0147545.
    PubMed     Text format     Abstract available


  71. CHOI HJ, Chung TW, Park MJ, Lee KS, et al
    Paeonia lactiflora Enhances the Adhesion of Trophoblast to the Endometrium via Induction of Leukemia Inhibitory Factor Expression.
    PLoS One. 2016;11:e0148232.
    PubMed     Text format     Abstract available


  72. MIZUGUCHI M, Sasaki Y, Hara T, Higuchi M, et al
    Induction of Cell Death in Growing Human T-Cells and Cell Survival in Resting Cells in Response to the Human T-Cell Leukemia Virus Type 1 Tax.
    PLoS One. 2016;11:e0148217.
    PubMed     Text format     Abstract available


  73. FOLLIN C, Gabery S, Petersen A, Sundgren PC, et al
    Associations between Metabolic Risk Factors and the Hypothalamic Volume in Childhood Leukemia Survivors Treated with Cranial Radiotherapy.
    PLoS One. 2016;11:e0147575.
    PubMed     Text format     Abstract available


  74. HUSAIN I, Sharma A, Kumar S, Malik F, et al
    Purification and Characterization of Glutaminase Free Asparaginase from Enterobacter cloacae: In-Vitro Evaluation of Cytotoxic Potential against Human Myeloid Leukemia HL-60 Cells.
    PLoS One. 2016;11:e0148877.
    PubMed     Text format     Abstract available


  75. IBANEZ M, Carbonell-Caballero J, Garcia-Alonso L, Such E, et al
    The Mutational Landscape of Acute Promyelocytic Leukemia Reveals an Interacting Network of Co-Occurrences and Recurrent Mutations.
    PLoS One. 2016;11:e0148346.
    PubMed     Text format     Abstract available


  76. FORERO-CASTRO M, Robledo C, Benito R, Abaigar M, et al
    Genome-Wide DNA Copy Number Analysis of Acute Lymphoblastic Leukemia Identifies New Genetic Markers Associated with Clinical Outcome.
    PLoS One. 2016;11:e0148972.
    PubMed     Text format     Abstract available


  77. FISCHER M, Spies-Weisshart B, Schrenk K, Gruhn B, et al
    Polymorphisms of Dectin-1 and TLR2 Predispose to Invasive Fungal Disease in Patients with Acute Myeloid Leukemia.
    PLoS One. 2016;11:e0150632.
    PubMed     Text format     Abstract available


  78. KASAR S, Underbayev C, Hassan M, Ilev I, et al
    Alterations in the mir-15a/16-1 Loci Impairs Its Processing and Augments B-1 Expansion in De Novo Mouse Model of Chronic Lymphocytic Leukemia (CLL).
    PLoS One. 2016;11:e0149331.
    PubMed     Text format     Abstract available


  79. SHOUVAL R, Labopin M, Unger R, Giebel S, et al
    Prediction of Hematopoietic Stem Cell Transplantation Related Mortality- Lessons Learned from the In-Silico Approach: A European Society for Blood and Marrow Transplantation Acute Leukemia Working Party Data Mining Study.
    PLoS One. 2016;11:e0150637.
    PubMed     Text format     Abstract available


  80. DUREN RP, Boudreaux SP, Conneely OM
    Genome Wide Mapping of NR4A Binding Reveals Cooperativity with ETS Factors to Promote Epigenetic Activation of Distal Enhancers in Acute Myeloid Leukemia Cells.
    PLoS One. 2016;11:e0150450.
    PubMed     Text format     Abstract available


  81. CHIARENZA A, Manetti F, Petricci E, Ruat M, et al
    Novel Acylguanidine Derivatives Targeting Smoothened Induce Antiproliferative and Pro-Apoptotic Effects in Chronic Myeloid Leukemia Cells.
    PLoS One. 2016;11:e0149919.
    PubMed     Text format     Abstract available


  82. VAN DEN BOOM J, Trusch F, Hoppstock L, Beuck C, et al
    Structural Characterization of the Loop at the Alpha-Subunit C-Terminus of the Mixed Lineage Leukemia Protein Activating Protease Taspase1.
    PLoS One. 2016;11:e0151431.
    PubMed     Text format     Abstract available


  83. HASEGAWA K, Tanaka S, Fujiki F, Morimoto S, et al
    Glycosylation Status of CD43 Protein Is Associated with Resistance of Leukemia Cells to CTL-Mediated Cytolysis.
    PLoS One. 2016;11:e0152326.
    PubMed     Text format     Abstract available


  84. WANG X, Zhou M, Fu Y, Sun T, et al
    RBP2 Promotes Adult Acute Lymphoblastic Leukemia by Upregulating BCL2.
    PLoS One. 2016;11:e0152142.
    PubMed     Text format     Abstract available


  85. MILUTINOVIC S, Heynen-Genel S, Chao E, Dewing A, et al
    Cardiac Glycosides Activate the Tumor Suppressor and Viral Restriction Factor Promyelocytic Leukemia Protein (PML).
    PLoS One. 2016;11:e0152692.
    PubMed     Text format     Abstract available


  86. FAHRENKROG B, Martinelli V, Nilles N, Fruhmann G, et al
    Expression of Leukemia-Associated Nup98 Fusion Proteins Generates an Aberrant Nuclear Envelope Phenotype.
    PLoS One. 2016;11:e0152321.
    PubMed     Text format     Abstract available


  87. SLOAN CE, Luskin MR, Boccuti AM, Sehgal AR, et al
    A Modified Integrated Genetic Model for Risk Prediction in Younger Patients with Acute Myeloid Leukemia.
    PLoS One. 2016;11:e0153016.
    PubMed     Text format     Abstract available


  88. TENG CJ, Huon LK, Hu YW, Yeh CM, et al
    Secondary Solid Organ Neoplasm in Patients with Acute Lymphoblastic Leukemia: A Nationwide Population-Based Study in Taiwan.
    PLoS One. 2016;11:e0152909.
    PubMed     Text format     Abstract available


  89. WALLACE J, Hu R, Mosbruger TL, Dahlem TJ, et al
    Genome-Wide CRISPR-Cas9 Screen Identifies MicroRNAs That Regulate Myeloid Leukemia Cell Growth.
    PLoS One. 2016;11:e0153689.
    PubMed     Text format     Abstract available


  90. ADMONI-ELISHA L, Nakdimon I, Shteinfer A, Prezma T, et al
    Novel Biomarker Proteins in Chronic Lymphocytic Leukemia: Impact on Diagnosis, Prognosis and Treatment.
    PLoS One. 2016;11:e0148500.
    PubMed     Text format     Abstract available


  91. FERRELL PB JR, Diggins KE, Polikowsky HG, Mohan SR, et al
    High-Dimensional Analysis of Acute Myeloid Leukemia Reveals Phenotypic Changes in Persistent Cells during Induction Therapy.
    PLoS One. 2016;11:e0153207.
    PubMed     Text format     Abstract available


  92. REBOLLEDA N, Losada-Fernandez I, Perez-Chacon G, Castejon R, et al
    Synergistic Activity of Deguelin and Fludarabine in Cells from Chronic Lymphocytic Leukemia Patients and in the New Zealand Black Murine Model.
    PLoS One. 2016;11:e0154159.
    PubMed     Text format     Abstract available


  93. CHENG EH, Liu JY, Lee TH, Huang CC, et al
    Requirement of Leukemia Inhibitory Factor or Epidermal Growth Factor for Pre-Implantation Embryogenesis via JAK/STAT3 Signaling Pathways.
    PLoS One. 2016;11:e0153086.
    PubMed     Text format     Abstract available


  94. POLAK A, Kiliszek P, Sewastianik T, Szydlowski M, et al
    MEK Inhibition Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia (B-ALL) Cells to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy.
    PLoS One. 2016;11:e0155893.
    PubMed     Text format     Abstract available


  95. LIN TY, Chen KC, Liu HJ, Liu AJ, et al
    MicroRNA-1301-Mediated RanGAP1 Downregulation Induces BCR-ABL Nuclear Entrapment to Enhance Imatinib Efficacy in Chronic Myeloid Leukemia Cells.
    PLoS One. 2016;11:e0156260.
    PubMed     Text format     Abstract available


  96. KANDA M, Nagai T, Takahashi T, Liu ML, et al
    Leukemia Inhibitory Factor Enhances Endogenous Cardiomyocyte Regeneration after Myocardial Infarction.
    PLoS One. 2016;11:e0156562.
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  97. SUZUKI T, Kazuki Y, Oshimura M, Hara T, et al
    Highly Efficient Transfer of Chromosomes to a Broad Range of Target Cells Using Chinese Hamster Ovary Cells Expressing Murine Leukemia Virus-Derived Envelope Proteins.
    PLoS One. 2016;11:e0157187.
    PubMed     Text format     Abstract available


  98. GIALLONGO C, Romano A, Parrinello NL, La Cava P, et al
    Mesenchymal Stem Cells (MSC) Regulate Activation of Granulocyte-Like Myeloid Derived Suppressor Cells (G-MDSC) in Chronic Myeloid Leukemia Patients.
    PLoS One. 2016;11:e0158392.
    PubMed     Text format     Abstract available


  99. MA Y, Liu L, Jin J, Lou Y, et al
    All-Trans Retinoic Acid plus Arsenic Trioxide versus All-Trans Retinoic Acid plus Chemotherapy for Newly Diagnosed Acute Promyelocytic Leukemia: A Meta-Analysis.
    PLoS One. 2016;11:e0158760.
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  100. WARRIS LT, van den Akker EL, Bierings MB, van den Bos C, et al
    Acute Activation of Metabolic Syndrome Components in Pediatric Acute Lymphoblastic Leukemia Patients Treated with Dexamethasone.
    PLoS One. 2016;11:e0158225.
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  101. JONAS BA, Johnson C, Gratzinger D, Majeti R, et al
    Alkylator-Induced and Patient-Derived Xenograft Mouse Models of Therapy-Related Myeloid Neoplasms Model Clinical Disease and Suggest the Presence of Multiple Cell Subpopulations with Leukemia Stem Cell Activity.
    PLoS One. 2016;11:e0159189.
    PubMed     Text format     Abstract available


  102. POTENZA L, Vallerini D, Barozzi P, Riva G, et al
    Mucorales-Specific T Cells in Patients with Hematologic Malignancies.
    PLoS One. 2016;11:e0149108.
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  103. ZHOU Y, Zhu J, Gu Z, Yin X, et al
    Efficacy of Exercise Interventions in Patients with Acute Leukemia: A Meta-Analysis.
    PLoS One. 2016;11:e0159966.
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  104. WESTON-BELL NJ, Tapper W, Gibson J, Bryant D, et al
    Exome Sequencing in Classic Hairy Cell Leukaemia Reveals Widespread Variation in Acquired Somatic Mutations between Individual Tumours Apart from the Signature BRAF V(600)E Lesion.
    PLoS One. 2016;11:e0149162.
    PubMed     Text format     Abstract available


  105. MATSUSHITA M, Otsuka Y, Tsutsumida N, Tanaka C, et al
    Identification of Novel HLA-A*24:02-Restricted Epitope Derived from a Homeobox Protein Expressed in Hematological Malignancies.
    PLoS One. 2016;11:e0146371.
    PubMed     Text format     Abstract available


  106. LI Y, Wei J, Mao X, Gao Q, et al
    Flow Cytometric Immunophenotyping Is Sensitive for the Early Diagnosis of De Novo Aggressive Natural Killer Cell Leukemia (ANKL): A Multicenter Retrospective Analysis.
    PLoS One. 2016;11:e0158827.
    PubMed     Text format     Abstract available


  107. PALLIS M, Harvey T, Russell N
    Phenotypically Dormant and Immature Leukaemia Cells Display Increased Ribosomal Protein S6 Phosphorylation.
    PLoS One. 2016;11:e0151480.
    PubMed     Text format     Abstract available


  108. WEEKS RJ, Ludgate JL, LeMee G, Morison IM, et al
    TESTIN Induces Rapid Death and Suppresses Proliferation in Childhood B Acute Lymphoblastic Leukaemia Cells.
    PLoS One. 2016;11:e0151341.
    PubMed     Text format     Abstract available


  109. POTUCKOVA E, Zuna J, Hovorkova L, Starkova J, et al
    Intragenic ERG Deletions Do Not Explain the Biology of ERG-Related Acute Lymphoblastic Leukemia.
    PLoS One. 2016;11:e0160385.
    PubMed     Text format     Abstract available


  110. BURDA P, Vargova J, Curik N, Salek C, et al
    GATA-1 Inhibits PU.1 Gene via DNA and Histone H3K9 Methylation of Its Distal Enhancer in Erythroleukemia.
    PLoS One. 2016;11:e0152234.
    PubMed     Text format     Abstract available


  111. TENG CJ, Huon LK, Hu YW, Yeh CM, et al
    Correction: Secondary Solid Organ Neoplasm in Patients with Acute Lymphoblastic Leukemia: A Nationwide Population-Based Study in Taiwan.
    PLoS One. 2016;11:e0162225.
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  112. EDWARDS H, Rubenstein M, Dombkowski AA, Caldwell JT, et al
    Gene Signature of High White Blood Cell Count in B-Precursor Acute Lymphoblastic Leukemia.
    PLoS One. 2016;11:e0161539.
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  113. BIRKENMEIER G, Hemdan NY, Kurz S, Bigl M, et al
    Ethyl Pyruvate Combats Human Leukemia Cells but Spares Normal Blood Cells.
    PLoS One. 2016;11:e0161571.
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  114. POHLEN M, Thoennissen NH, Braess J, Thudium J, et al
    Patients with Acute Myeloid Leukemia Admitted to Intensive Care Units: Outcome Analysis and Risk Prediction.
    PLoS One. 2016;11:e0160871.
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  115. SONTAKKE P, Koczula KM, Jaques J, Wierenga AT, et al
    Hypoxia-Like Signatures Induced by BCR-ABL Potentially Alter the Glutamine Uptake for Maintaining Oxidative Phosphorylation.
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  116. CEPPI F, Duval M, Leclerc JM, Laverdiere C, et al
    Improvement of the Outcome of Relapsed or Refractory Acute Lymphoblastic Leukemia in Children Using a Risk-Based Treatment Strategy.
    PLoS One. 2016;11:e0160310.
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  117. KUZNETSOVA IS, Labutina EV, Hunter N
    Radiation Risks of Leukemia, Lymphoma and Multiple Myeloma Incidence in the Mayak Cohort: 1948-2004.
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    PubMed     Text format     Abstract available


  118. CHEN D, Zheng J, Gerasimcik N, Lagerstedt K, et al
    The Expression Pattern of the Pre-B Cell Receptor Components Correlates with Cellular Stage and Clinical Outcome in Acute Lymphoblastic Leukemia.
    PLoS One. 2016;11:e0162638.
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  119. MULSOW K, Enzlein T, Delebinski C, Jaeger S, et al
    Impact of Mistletoe Triterpene Acids on the Uptake of Mistletoe Lectin by Cultured Tumor Cells.
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  120. ZHAO S, Liu W, Li Y, Liu P, et al
    Alternative Splice Variants Modulates Dominant-Negative Function of Helios in T-Cell Leukemia.
    PLoS One. 2016;11:e0163328.
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  121. KHAN N, Hills RK, Knapper S, Steadman L, et al
    Normal Hematopoietic Progenitor Subsets Have Distinct Reactive Oxygen Species, BCL2 and Cell-Cycle Profiles That Are Decoupled from Maturation in Acute Myeloid Leukemia.
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  122. SCHLIEMANN C, Gerss J, Wiebe S, Mikesch JH, et al
    A Phase I Dose Escalation Study of the Triple Angiokinase Inhibitor Nintedanib Combined with Low-Dose Cytarabine in Elderly Patients with Acute Myeloid Leukemia.
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  123. XIE M, Jiang Q, Li L, Zhu J, et al
    HAG (Homoharringtonine, Cytarabine, G-CSF) Regimen for the Treatment of Acute Myeloid Leukemia and Myelodysplastic Syndrome: A Meta-Analysis with 2,314 Participants.
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  124. ZHANG M, Fu H, Lai X, Tan Y, et al
    Minimal Residual Disease at First Achievement of Complete Remission Predicts Outcome in Adult Patients with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia.
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  125. WASS M, Hitz F, Schaffrath J, Muller-Tidow C, et al
    Value of Different Comorbidity Indices for Predicting Outcome in Patients with Acute Myeloid Leukemia.
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  126. COX CV, Diamanti P, Moppett JP, Blair A, et al
    Investigating CD99 Expression in Leukemia Propagating Cells in Childhood T Cell Acute Lymphoblastic Leukemia.
    PLoS One. 2016;11:e0165210.
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  127. BALDOW C, Thielecke L, Glauche I
    Model Based Analysis of Clonal Developments Allows for Early Detection of Monoclonal Conversion and Leukemia.
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  128. MAS-Y-MAS S, Barbon M, Teyssier C, Demene H, et al
    The Human Mixed Lineage Leukemia 5 (MLL5), a Sequentially and Structurally Divergent SET Domain-Containing Protein with No Intrinsic Catalytic Activity.
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  129. MINAGAWA K, Jamil MO, Al-Obaidi M, Pereboeva L, et al
    In Vitro Pre-Clinical Validation of Suicide Gene Modified Anti-CD33 Redirected Chimeric Antigen Receptor T-Cells for Acute Myeloid Leukemia.
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  130. YANG Y, Kelly PJ, Bai J, Zhang R, et al
    First Molecular Characterization of Bovine Leukemia Virus Infections in the Caribbean.
    PLoS One. 2016;11:e0168379.
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  131. KIM JA, Hwang B, Park SN, Huh S, et al
    Genomic Profile of Chronic Lymphocytic Leukemia in Korea Identified by Targeted Sequencing.
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  132. BENKISSER-PETERSEN M, Buchner M, Dorffel A, Duhren-von-Minden M, et al
    Spleen Tyrosine Kinase Is Involved in the CD38 Signal Transduction Pathway in Chronic Lymphocytic Leukemia.
    PLoS One. 2016;11:e0169159.
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  133. CHEN Y, Fang F, Hu Y, Liu Q, et al
    The Polymorphisms in LNK Gene Correlated to the Clinical Type of Myeloproliferative Neoplasms.
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    January 2015
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    Improved Detection of Invasive Pulmonary Aspergillosis Arising during Leukemia Treatment Using a Panel of Host Response Proteins and Fungal Antigens.
    PLoS One. 2015;10:e0143165.
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  135. YANG YL, Yen CT, Pai CH, Chen HY, et al
    A Double Negative Loop Comprising ETV6/RUNX1 and MIR181A1 Contributes to Differentiation Block in t(12;21)-Positive Acute Lymphoblastic Leukemia.
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  136. PAIVA C, Godbersen JC, Soderquist RS, Rowland T, et al
    Cyclin-Dependent Kinase Inhibitor P1446A Induces Apoptosis in a JNK/p38 MAPK-Dependent Manner in Chronic Lymphocytic Leukemia B-Cells.
    PLoS One. 2015;10:e0143685.
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  137. JANG SH, Lee S, Chung HY
    Characterization of Leukemia-Inducing Genes Using a Proto-Oncogene/Homeobox Gene Retroviral Human cDNA Library in a Mouse In Vivo Model.
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  138. HERNANDEZ JA, Hernandez-Sanchez M, Rodriguez-Vicente AE, Grossmann V, et al
    A Low Frequency of Losses in 11q Chromosome Is Associated with Better Outcome and Lower Rate of Genomic Mutations in Patients with Chronic Lymphocytic Leukemia.
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  139. CUOMO RE, Garland CF, Gorham ED, Mohr SB, et al
    Low Cloud Cover-Adjusted Ultraviolet B Irradiance Is Associated with High Incidence Rates of Leukemia: Study of 172 Countries.
    PLoS One. 2015;10:e0144308.
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  140. HASEGAWA K, Tanaka S, Fujiki F, Morimoto S, et al
    An Immunocompetent Mouse Model for MLL/AF9 Leukemia Reveals the Potential of Spontaneous Cytotoxic T-Cell Response to an Antigen Expressed in Leukemia Cells.
    PLoS One. 2015;10:e0144594.
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  141. DING X, Jiang W, Zhou P, Liu L, et al
    Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O-GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7).
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  142. SAKAGUCHI H, Muramatsu H, Okuno Y, Makishima H, et al
    Aberrant DNA Methylation Is Associated with a Poor Outcome in Juvenile Myelomonocytic Leukemia.
    PLoS One. 2015;10:e0145394.
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  143. Correction: Three-Dimensional Microfluidic Tri-Culture Model of the Bone Marrow Microenvironment for Study of Acute Lymphoblastic Leukemia.
    PLoS One. 2015;10:e0146203.
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  144. LIU N, Li P, Zang S, Liu Q, et al
    Novel agent nitidine chloride induces erythroid differentiation and apoptosis in CML cells through c-Myc-miRNAs axis.
    PLoS One. 2015;10:e0116880.
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  145. GANJALI M, Baghfalaki T, Berridge D
    Robust modeling of differential gene expression data using normal/independent distributions: a Bayesian approach.
    PLoS One. 2015;10:e0123791.
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  146. RAC M, Krupka M, Binder S, Sedlarova M, et al
    Oxidative damage of U937 human leukemic cells caused by hydroxyl radical results in singlet oxygen formation.
    PLoS One. 2015;10:e0116958.
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  147. SHANG W, Ning Y, Xu X, Li M, et al
    Incidence of Cancer in ANCA-Associated Vasculitis: A Meta-Analysis of Observational Studies.
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  148. MAURA F, Mosca L, Fabris S, Cutrona G, et al
    Insulin growth factor 1 receptor expression is associated with NOTCH1 mutation, trisomy 12 and aggressive clinical course in chronic lymphocytic leukaemia.
    PLoS One. 2015;10:e0118801.
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  149. GUO J, Roberts L, Chen Z, Merta PJ, et al
    JAK2V617F drives Mcl-1 expression and sensitizes hematologic cell lines to dual inhibition of JAK2 and Bcl-xL.
    PLoS One. 2015;10:e0114363.
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  150. TRISSAL MC, DeMoya RA, Schmidt AP, Link DC, et al
    MicroRNA-223 regulates granulopoiesis but is not required for HSC maintenance in mice.
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  151. CHANET R, Kienda G, Heneman-Masurel A, Vernis L, et al
    Yeast Assay Highlights the Intrinsic Genomic Instability of Human PML Intron 6 over Intron 3 and the Role of Replication Fork Proteins.
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  152. NIAVARANI A, Currie E, Reyal Y, Anjos-Afonso F, et al
    APOBEC3A is implicated in a novel class of G-to-A mRNA editing in WT1 transcripts.
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  153. RETA C, Altamirano L, Gonzalez JA, Diaz-Hernandez R, et al
    Segmentation and Classification of Bone Marrow Cells Images Using Contextual Information for Medical Diagnosis of Acute Leukemias.
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  154. BAUMER N, Baumer S, Haak M, Koschmieder S, et al
    A Limited Role for the Cell Cycle Regulator Cyclin A1 in Murine Leukemogenesis.
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  155. BACHAS C, Schuurhuis GJ, Zwaan CM, van den Heuvel-Eibrink MM, et al
    Gene expression profiles associated with pediatric relapsed AML.
    PLoS One. 2015;10:e0121730.
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  156. MUSHTAQ M, Darekar S, Klein G, Kashuba E, et al
    Different Mechanisms of Regulation of the Warburg Effect in Lymphoblastoid and Burkitt Lymphoma Cells.
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  157. KUTSZEGI N, Semsei AF, Gezsi A, Sagi JC, et al
    Subgroups of Paediatric Acute Lymphoblastic Leukaemia Might Differ Significantly in Genetic Predisposition to Asparaginase Hypersensitivity.
    PLoS One. 2015;10:e0140136.
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  158. CARON JM, Caron JM
    Methyl Sulfone Blocked Multiple Hypoxia- and Non-Hypoxia-Induced Metastatic Targets in Breast Cancer Cells and Melanoma Cells.
    PLoS One. 2015;10:e0141565.
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  159. HAYES JE, Trynka G, Vijai J, Offit K, et al
    Tissue-Specific Enrichment of Lymphoma Risk Loci in Regulatory Elements.
    PLoS One. 2015;10:e0139360.
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    January 2014
  160. HWANG KK, Trama AM, Kozink DM, Chen X, et al
    IGHV1-69 B Cell Chronic Lymphocytic Leukemia Antibodies Cross-React with HIV-1 and Hepatitis C Virus Antigens as Well as Intestinal Commensal Bacteria.
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