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1 Am J Clin Pathol
2 Blood
1 BMC Genomics
1 Bone Marrow Transplant
1 Br J Cancer
3 Cancer
1 Cancer Lett
1 Eur J Haematol
3 Exp Hematol
1 Int J Hematol
1 J Biol Chem
1 J Clin Oncol
4 J Pediatr Hematol Oncol
4 Leuk Lymphoma
4 Leuk Res
6 Leukemia
1 Nat Rev Cancer
2 PLoS One

  Retrieve available abstracts of this week’s articles:
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    Am J Clin Pathol

  1. WU B, Jug R, Luedke C, Su P, et al
    Lineage Switch Between B-Lymphoblastic Leukemia and Acute Myeloid Leukemia Intermediated by "Occult" Myelodysplastic Neoplasm: Two Cases of Adult Patients With Evidence of Genomic Instability and Clonal Selection by Chemotherapy.
    Am J Clin Pathol. 2017;148:136-147.
    PubMed     Text format     Abstract available


  2. MAN N, Tan Y, Sun XJ, Liu F, et al
    Caspase-3 controls AML1-ETO-driven leukemogenesis via autophagy modulation in a ULK1-dependent manner.
    Blood. 2017;129:2782-2792.
    PubMed     Text format     Abstract available

  3. HOVORKOVA L, Zaliova M, Venn NC, Bleckmann K, et al
    Monitoring of childhood ALL using BCR-ABL1 genomic breakpoints identifies a subgroup with CML-like biology.
    Blood. 2017;129:2771-2781.
    PubMed     Text format     Abstract available

    BMC Genomics

  4. GEORGIADIS P, Liampa I, Hebels DG, Krauskopf J, et al
    Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis.
    BMC Genomics. 2017;18:728.
    PubMed     Text format     Abstract available

    Bone Marrow Transplant

  5. SCHEID C, de Wreede L, van Biezen A, Koenecke C, et al
    Validation of the revised IPSS at transplant in patients with myelodysplastic syndrome/transformed acute myelogenous leukemia receiving allogeneic stem cell transplantation: a retrospective analysis of the EBMT chronic malignancies working party.
    Bone Marrow Transplant. 2017 Sep 11. doi: 10.1038/bmt.2017.
    PubMed     Text format     Abstract available

    Br J Cancer

  6. PIATOPOULOU D, Avgeris M, Marmarinos A, Xagorari M, et al
    miR-125b predicts childhood acute lymphoblastic leukaemia poor response to BFM chemotherapy treatment.
    Br J Cancer. 2017;117:801-812.
    PubMed     Text format     Abstract available


  7. CHANG YJ, Wang Y, Mo XD, Zhang XH, et al
    Optimal dose of rabbit thymoglobulin in conditioning regimens for unmanipulated, haploidentical, hematopoietic stem cell transplantation: Long-term outcomes of a prospective randomized trial.
    Cancer. 2017 Mar 16. doi: 10.1002/cncr.30540.
    PubMed     Text format     Abstract available

  8. NICOLINI FE, Basak GW, Kim DW, Olavarria E, et al
    Overall survival with ponatinib versus allogeneic stem cell transplantation in Philadelphia chromosome-positive leukemias with the T315I mutation.
    Cancer. 2017 Apr 7. doi: 10.1002/cncr.30558.
    PubMed     Text format     Abstract available

  9. MEDHANIE GA, Fedewa SA, Adissu H, DeSantis CE, et al
    Cancer incidence profile in sub-Saharan African-born blacks in the United States: Similarities and differences with US-born non-Hispanic blacks.
    Cancer. 2017;123:3116-3124.
    PubMed     Text format     Abstract available

    Cancer Lett

  10. COLLADO R, Puiggros A, Lopez-Guerrero JA, Calasanz MJ, et al
    Chronic lymphocytic leukemia with isochromosome 17q: An aggressive subgroup associated with TP53 mutations and complex karyotypes.
    Cancer Lett. 2017 Sep 6. pii: S0304-3835(17)30536.
    PubMed     Text format     Abstract available

    Eur J Haematol

  11. SZARZYNSKA-ZAWADZKA B, Kosmalska M, Sedek L, Sonsala A, et al
    Cost-effective screening of DNMT3A coding sequence identifies somatic mutation in pediatric T-cell acute lymphoblastic leukemia.
    Eur J Haematol. 2017 Sep 14. doi: 10.1111/ejh.12964.
    PubMed     Text format     Abstract available

    Exp Hematol

  12. LEPRETRE S, Graux C, Touzart A, Macintyre E, et al
    Adult T-type lymphoblastic lymphoma: Treatment advances and prognostic indicators.
    Exp Hematol. 2017;51:7-16.
    PubMed     Text format     Abstract available

  13. CARRETTA M, de Boer B, Jaques J, Antonelli A, et al
    Genetically engineered mesenchymal stromal cells produce IL-3 and TPO to further improve human scaffold-based xenograft models.
    Exp Hematol. 2017;51:36-46.
    PubMed     Text format     Abstract available

  14. SADOVNIK I, Herrmann H, Eisenwort G, Blatt K, et al
    Expression of CD25 on Leukemic Stem Cells in BCR-ABL1+ CML: Potential Diagnostic Value and Functional Implications.
    Exp Hematol. 2017 Apr 27. pii: S0301-472X(17)30135.
    PubMed     Text format     Abstract available

    Int J Hematol

  15. KOBAYASHI Y, Munakata W, Ogura M, Uchida T, et al
    Phase I study of panobinostat and 5-azacitidine in Japanese patients with myelodysplastic syndrome or chronic myelomonocytic leukemia.
    Int J Hematol. 2017 Sep 13. doi: 10.1007/s12185-017-2327.
    PubMed     Text format     Abstract available

    J Biol Chem

  16. HIRBAWI J, Bialkowska K, Bledzka KM, Liu J, et al
    The extreme C-terminal region of kindlin-2 is critical to its regulation of integrin activation.
    J Biol Chem. 2017;292:14258-14269.
    PubMed     Text format     Abstract available

    J Clin Oncol

  17. OSTGARD LSG, Norgaard M, Medeiros BC, Friis LS, et al
    Effects of Education and Income on Treatment and Outcome in Patients With Acute Myeloid Leukemia in a Tax-Supported Health Care System: A National Population-Based Cohort Study.
    J Clin Oncol. 2017 Sep 11:JCO2017736728. doi: 10.1200/JCO.2017.73.6728.
    PubMed     Text format     Abstract available

    J Pediatr Hematol Oncol

  18. FRAINT E, Miller R, Walter A
    Posterior Reversible Encephalopathy Syndrome and Cerebral Sinus Thrombosis in a Case of Pediatric B-Cell ALL.
    J Pediatr Hematol Oncol. 2017;39:e71-e73.
    PubMed     Text format     Abstract available

  19. BORGES ML, Capela de Matos RR, Amaral BD, Soares-Ventura EM, et al
    Molecular Cytogenetic Approach to Characterize Novel and Cryptic Chromosome Abnormalities in Childhood Myeloid Malignances of Fanconi Anemia.
    J Pediatr Hematol Oncol. 2017;39:e85-e91.
    PubMed     Text format     Abstract available

  20. WHITTLE SB, Punia JN, Lopez-Terrada D, Gaikwad A, et al
    Therapy-related Acute Leukemia With Mixed Phenotype and Novel t(1: 6)(q25;p23) After Treatment for High-risk Neuroblastoma.
    J Pediatr Hematol Oncol. 2017 Sep 8. doi: 10.1097/MPH.0000000000000956.
    PubMed     Text format     Abstract available

  21. DEGNIN M, Agarwal A, Tarlock K, Meshinchi S, et al
    Novel Method Enabling the Use of Cryopreserved Primary Acute Myeloid Leukemia Cells in Functional Drug Screens.
    J Pediatr Hematol Oncol. 2017 Sep 12. doi: 10.1097/MPH.0000000000000946.
    PubMed     Text format     Abstract available

    Leuk Lymphoma

  22. PULA A, Stawiski K, Braun M, Iskierka-Jazdzewska E, et al
    Efficacy and safety of B-cell receptor signaling pathway inhibitors in relapsed/refractory chronic lymphocytic leukemia: a systematic review and meta-analysis of randomized clinical trials.
    Leuk Lymphoma. 2017 Sep 11:1-11. doi: 10.1080/10428194.2017.1375101.
    PubMed     Text format     Abstract available

  23. TAVARES M, Lemiale V, Mokart D, Pene F, et al
    Determinants of 1-year survival in critically ill acute leukemia patients: a GRRR-OH study.
    Leuk Lymphoma. 2017 Sep 13:1-9. doi: 10.1080/10428194.2017.1375106.
    PubMed     Text format     Abstract available

  24. VAUGHN JL, Kline D, Denlinger NM, Andritsos LA, et al
    Predictive performance of early warning scores in acute leukemia patients receiving induction chemotherapy.
    Leuk Lymphoma. 2017 Sep 13:1-3. doi: 10.1080/10428194.2017.1376744.
    PubMed     Text format    

  25. MESCHER C, Gilbertson D, Randall NM, Tarchand G, et al
    The impact of Agent Orange exposure on prognosis and management in patients with chronic lymphocytic leukemia: a National Veteran Affairs Tumor Registry Study.
    Leuk Lymphoma. 2017 Sep 14:1-8. doi: 10.1080/10428194.2017.1375109.
    PubMed     Text format     Abstract available

    Leuk Res

  26. LI D, Gale RP, Liu Y, Lei B, et al
    5'-Triphosphate siRNA targeting MDR1 reverses multi-drug resistance and activates RIG-I-induced immune-stimulatory and apoptotic effects against human myeloid leukaemia cells.
    Leuk Res. 2017;58:23-30.
    PubMed     Text format     Abstract available

  27. SZURIAN K, Csala I, Piurko V, Deak L, et al
    Quantitative miR analysis in chronic lymphocytic leukaemia/small lymphocytic lymphoma - proliferation centres are characterized by high miR-92a and miR-155 and low miR-150 expression.
    Leuk Res. 2017;58:39-42.
    PubMed     Text format     Abstract available

  28. SUKEGAWA M, Wang X, Nishioka C, Pan B, et al
    The BCR/ABL tyrosine kinase inhibitor, nilotinib, stimulates expression of IL-1beta in vascular endothelium in association with downregulation of miR-3p.
    Leuk Res. 2017;58:83-90.
    PubMed     Text format     Abstract available

  29. COMONT T, Tavitian S, Bardiaux L, Fort M, et al
    Platelet transfusion refractoriness in patients with acute myeloid leukemia treated by intensive chemotherapy.
    Leuk Res. 2017;61:62-67.
    PubMed     Text format     Abstract available


  30. LIU TH, Tang YJ, Huang Y, Wang L, et al
    Expression of the fetal hematopoiesis regulator FEV indicates leukemias of prenatal origin.
    Leukemia. 2017;31:1079-1086.
    PubMed     Text format     Abstract available

  31. MALANI D, Murumagi A, Yadav B, Kontro M, et al
    Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML.
    Leukemia. 2017;31:1187-1195.
    PubMed     Text format     Abstract available

  32. KAZIANKA L, Drucker C, Skrabs C, Thomas W, et al
    Ristocetin-induced platelet aggregation for monitoring of bleeding tendency in CLL treated with ibrutinib.
    Leukemia. 2017;31:1117-1122.
    PubMed     Text format     Abstract available

  33. LEROY E, Constantinescu SN
    Rethinking JAK2 inhibition: towards novel strategies of more specific and versatile janus kinase inhibition.
    Leukemia. 2017;31:1023-1038.
    PubMed     Text format     Abstract available

  34. REITER K, Polzer H, Krupka C, Maiser A, et al
    Tyrosine kinase inhibition increases the cell surface localization of FLT3-ITD and enhances FLT3-directed immunotherapy of acute myeloid leukemia.
    Leukemia. 2017 Aug 14. doi: 10.1038/leu.2017.
    PubMed     Text format     Abstract available

  35. TAKAO S, Chien W, Madan V, Lin DC, et al
    Targeting the vulnerability to NAD+ depletion in B-cell acute lymphoblastic leukemia.
    Leukemia. 2017 Sep 14. doi: 10.1038/leu.2017.
    PubMed     Text format     Abstract available

    Nat Rev Cancer

  36. MCNERNEY ME, Godley LA, Le Beau MM
    Therapy-related myeloid neoplasms: when genetics and environment collide.
    Nat Rev Cancer. 2017;17:513-527.
    PubMed     Text format     Abstract available

    PLoS One

  37. LAVROV AV, Ustaeva OA, Adilgereeva EP, Smirnikhina SA, et al
    Copy number variation analysis in cytochromes and glutathione S-transferases may predict efficacy of tyrosine kinase inhibitors in chronic myeloid leukemia.
    PLoS One. 2017;12:e0182901.
    PubMed     Text format     Abstract available

  38. WANG Y, Yin Y, Lan X, Ye F, et al
    Molecular characterization, expression of chicken TBK1 gene and its effect on IRF3 signaling pathway.
    PLoS One. 2017;12:e0177608.
    PubMed     Text format     Abstract available

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