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Amedeo Prize 2008
The 21 Finalists


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Articles published in Oncogene

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Single Articles


    April 2008
  1. SUKHAI MA , Thomas M, Xuan Y, Chan LS, et al
    Evidence of functional interaction between NuMA-RARalpha and RXRalpha in an in vivo model of acute promyelocytic leukemia.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


  2. LIN K , Rockliffe N, Johnson GG, Sherrington PD, et al
    Hsp90 inhibition has opposing effects on wild-type and mutant p53 and induces p21 expression and cytotoxicity irrespective of p53/ATM status in chronic lymphocytic leukaemia cells.
    Oncogene. 2008;27:2445-55.
    PubMed     Related articles    Abstract available


    March 2008
  3. SAHAY S , Pannucci NL, Mahon GM, Rodriguez PL, et al
    The RhoGEF domain of p210 Bcr-Abl activates RhoA and is required for transformation.
    Oncogene. 2008;27:2064-71.
    PubMed     Related articles    Abstract available


  4. CANO F , Drynan LF, Pannell R, Rabbitts TH, et al
    Leukaemia lineage specification caused by cell-specific Mll-Enl translocations.
    Oncogene. 2008;27:1945-50.
    PubMed     Related articles    Abstract available


  5. NIETO-MIGUEL T , Gajate C, Gonzalez-Camacho F, Mollinedo F, et al
    Proapoptotic role of Hsp90 by its interaction with c-Jun N-terminal kinase in lipid rafts in edelfosine-mediated antileukemic therapy.
    Oncogene. 2008;27:1779-87.
    PubMed     Related articles    Abstract available


  6. BARBETTI V , Gozzini A, Rovida E, Morandi A, et al
    Selective anti-leukaemic activity of low-dose histone deacetylase inhibitor ITF2357 on AML1/ETO-positive cells.
    Oncogene. 2008;27:1767-78.
    PubMed     Related articles    Abstract available


    February 2008
  7. DATTA A , Nicot C
    Telomere attrition induces a DNA double-strand break damage signal that reactivates p53 transcription in HTLV-I leukemic cells.
    Oncogene. 2008;27:1135-41.
    PubMed     Related articles    Abstract available


  8. LO YH , Wu CC, Shih HM, Lai MZ, et al
    Selective activation of NFAT by promyelocytic leukemia protein.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


  9. COSTOYA JA , Hobbs RM, Pandolfi PP
    Cyclin-dependent kinase antagonizes promyelocytic leukemia zinc-finger through phosphorylation.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


    January 2008
  10. NARDI V , Raz T, Cao X, Wu CJ, et al
    Quantitative monitoring by polymerase colony assay of known mutations resistant to ABL kinase inhibitors.
    Oncogene. 2008;27:775-82.
    PubMed     Related articles    Abstract available


  11. SONG LP , Zhang J, Wu SF, Huang Y, et al
    Hypoxia-inducible factor-1alpha-induced differentiation of myeloid leukemic cells is its transcriptional activity independent.
    Oncogene. 2008;27:519-27.
    PubMed     Related articles    Abstract available


  12. MIZUNO T , Yamasaki N, Miyazaki K, Tazaki T, et al
    Overexpression/enhanced kinase activity of BCR/ABL and altered expression of Notch1 induced acute leukemia in p210BCR/ABL transgenic mice.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


    December 2007
  13. PAN Q , Zhu YJ, Gu BW, Cai X, et al
    A new fusion gene NUP98-IQCG identified in an acute T-lymphoid/myeloid leukemia with a t(3;11)(q29q13;p15)del(3)(q29) translocation.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  14. SUGIMOTO K , Sasaki M, Isobe Y, Tsutsui M, et al
    Hsp90-inhibitor geldanamycin abrogates G(2) arrest in p53-negative leukemia cell lines through the depletion of Chk1.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  15. NAKAYAMA T , Hieshima K, Arao T, Jin Z, et al
    Aberrant expression of Fra-2 promotes CCR4 expression and cell proliferation in adult T-cell leukemia.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


    October 2007
  16. CHINEN Y , Taki T, Nishida K, Shimizu D, et al
    Identification of the novel AML1 fusion partner gene, LAF4, a fusion partner of MLL, in childhood T-cell acute lymphoblastic leukemia with t(2;21)(q11;q22) by bubble PCR method for cDNA.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  17. LIN YC , Diccianni MB, Kim Y, Lin HH, et al
    Human p16gamma, a novel transcriptional variant of p16(INK4A), coexpresses with p16(INK4A) in cancer cells and inhibits cell-cycle progression.
    Oncogene. 2007;26:7017-27.
    PubMed     Related articles    Abstract available


  18. VAN ETTEN RA
    Aberrant cytokine signaling in leukemia.
    Oncogene. 2007;26:6738-49.
    PubMed     Related articles    Abstract available


  19. PABST T , Mueller BU
    Transcriptional dysregulation during myeloid transformation in AML.
    Oncogene. 2007;26:6829-37.
    PubMed     Related articles    Abstract available


  20. WICKREMA A , Crispino JD
    Erythroid and megakaryocytic transformation.
    Oncogene. 2007;26:6803-15.
    PubMed     Related articles    Abstract available


  21. ARGIROPOULOS B , Humphries RK
    Hox genes in hematopoiesis and leukemogenesis.
    Oncogene. 2007;26:6766-76.
    PubMed     Related articles    Abstract available


  22. KIDA A , Kakihana K, Kotani S, Kurosu T, et al
    Glycogen synthase kinase-3beta and p38 phosphorylate cyclin D2 on Thr280 to trigger its ubiquitin/proteasome-dependent degradation in hematopoietic cells.
    Oncogene. 2007;26:6630-40.
    PubMed     Related articles    Abstract available


    September 2007
  23. ZHEN Y , Sorensen V, Jin Y, Suo Z, et al
    Indirubin-3'-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1/2 activity via p38 MAPK.
    Oncogene. 2007;26:6372-85.
    PubMed     Related articles    Abstract available


    August 2007
  24. KARAGIANNI P , Wong J
    HDAC3: taking the SMRT-N-CoRrect road to repression.
    Oncogene. 2007;26:5439-49.
    PubMed     Related articles    Abstract available


    July 2007
  25. ANGELONI D , Danilkovitch-Miagkova A, Ivanova T, Braga E, et al
    Hypermethylation of Ron proximal promoter associates with lack of full-length Ron and transcription of oncogenic short-Ron from an internal promoter.
    Oncogene. 2007;26:4499-512.
    PubMed     Related articles    Abstract available


    June 2007
  26. GIBBS JD , Liebermann DA, Hoffman B
    Egr-1 abrogates the E2F-1 block in terminal myeloid differentiation and suppresses leukemia.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  27. LI QF , Huang WR, Duan HF, Wang H, et al
    Sphingosine kinase-1 mediates BCR/ABL-induced upregulation of Mcl-1 in chronic myeloid leukemia cells.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  28. CHENG K , Grisendi S, Clohessy JG, Majid S, et al
    The leukemia-associated cytoplasmic nucleophosmin mutant is an oncogene with paradoxical functions: Arf inactivation and induction of cellular senescence.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


    May 2007
  29. GRABARCZYK P , Przybylski GK, Depke M, Volker U, et al
    Inhibition of BCL11B expression leads to apoptosis of malignant but not normal mature T cells.
    Oncogene. 2007;26:3797-810.
    PubMed     Related articles    Abstract available


  30. LI XL , Arai Y, Harada H, Shima Y, et al
    Mutations of the HIPK2 gene in acute myeloid leukemia and myelodysplastic syndrome impair AML1- and p53-mediated transcription.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  31. WALDMANN TA
    Daclizumab (anti-Tac, Zenapax) in the treatment of leukemia/lymphoma.
    Oncogene. 2007;26:3699-703.
    PubMed     Related articles    Abstract available


  32. PAGANO L , Fianchi L, Caira M, Rutella S, et al
    The role of Gemtuzumab Ozogamicin in the treatment of acute myeloid leukemia patients.
    Oncogene. 2007;26:3679-90.
    PubMed     Related articles    Abstract available


  33. ALINARI L , Lapalombella R, Andritsos L, Baiocchi RA, et al
    Alemtuzumab (Campath-1H) in the treatment of chronic lymphocytic leukemia.
    Oncogene. 2007;26:3644-53.
    PubMed     Related articles    Abstract available


  34. LEONARD JP , Goldenberg DM
    Preclinical and clinical evaluation of epratuzumab (anti-CD22 IgG) in B-cell malignancies.
    Oncogene. 2007;26:3704-13.
    PubMed     Related articles    Abstract available


  35. IOTTI G , Ferrari-Amorotti G, Rosafio C, Corradini F, et al
    Expression of CCL9/MIP-1gamma is repressed by BCR/ABL and its restoration suppresses in vivo leukemogenesis of 32D-BCR/ABL cells.
    Oncogene. 2007;26:3482-91.
    PubMed     Related articles    Abstract available


  36. TICCHIONI M , Essafi M, Jeandel PY, Davi F, et al
    Homeostatic chemokines increase survival of B-chronic lymphocytic leukemia cells through inactivation of transcription factor FOXO3a.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  37. KUROSU T , Tsuji K, Kida A, Koyama T, et al
    Rottlerin synergistically enhances imatinib-induced apoptosis of BCR/ABL-expressing cells through its mitochondrial uncoupling effect independent of protein kinase C-delta.
    Oncogene. 2007;26:2975-87.
    PubMed     Related articles    Abstract available


  38. VESELY DL , Hoffman B, Liebermann DA
    Phosphatidylinositol 3-kinase/Akt signaling mediates interleukin-6 protection against p53-induced apoptosis in M1 myeloid leukemic cells.
    Oncogene. 2007;26:3041-50.
    PubMed     Related articles    Abstract available


    April 2007
  39. MA C , Zhang J, Durrin LK, Lv J, et al
    The BCL2 major breakpoint region (mbr) regulates gene expression.
    Oncogene. 2007;26:2649-57.
    PubMed     Related articles    Abstract available


  40. JACQUEL A , Colosetti P, Grosso S, Belhacene N, et al
    Apoptosis and erythroid differentiation triggered by Bcr-Abl inhibitors in CML cell lines are fully distinguishable processes that exhibit different sensitivity to caspase inhibition.
    Oncogene. 2007;26:2445-58.
    PubMed     Related articles    Abstract available


    March 2007
  41. ERKELAND SJ , Aarts LH, Irandoust M, Roovers O, et al
    Novel role of WD40 and SOCS box protein-2 in steady-state distribution of granulocyte colony-stimulating factor receptor and G-CSF-controlled proliferation and differentiation signaling.
    Oncogene. 2007;26:1985-94.
    PubMed     Related articles    Abstract available


  42. VAN WELY KH , Meester-Smoor MA, Janssen MJ, Aarnoudse AJ, et al
    The MN1-TEL myeloid leukemia-associated fusion protein has a dominant-negative effect on RAR-RXR-mediated transcription.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  43. PEREZ-CARO M , Gutierrez-Cianca N, Gonzalez-Herrero I, Lopez-Hernandez I, et al
    Sustained leukaemic phenotype after inactivation of BCR-ABLp190 in mice.
    Oncogene. 2007;26:1702-13.
    PubMed     Related articles    Abstract available


  44. FLOTHO C , Steinemann D, Mullighan CG, Neale G, et al
    Genome-wide single-nucleotide polymorphism analysis in juvenile myelomonocytic leukemia identifies uniparental disomy surrounding the NF1 locus in cases associated with neurofibromatosis but not in cases with mutant RAS or PTPN11.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  45. CAPORALI A , Wark L, Vermolen BJ, Garini Y, et al
    Telomeric aggregates and end-to-end chromosomal fusions require myc box II.
    Oncogene. 2007;26:1398-406.
    PubMed     Related articles    Abstract available


    February 2007
  46. PRABHU S , Saadat D, Zhang M, Halbur L, et al
    A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation.
    Oncogene. 2007;26:1188-200.
    PubMed     Related articles    Abstract available


  47. PICKERING BM , de Mel S, Lee M, Howell M, et al
    Pharmacological inhibitors of NF-kappaB accelerate apoptosis in chronic lymphocytic leukaemia cells.
    Oncogene. 2007;26:1166-77.
    PubMed     Related articles    Abstract available


  48. FLEISIG HB , Orazio NI, Liang H, Tyler AF, et al
    Adenoviral E1B55K oncoprotein sequesters candidate leukemia suppressor sequence-specific single-stranded DNA-binding protein 2 into aggresomes.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  49. OTT RG , Simma O, Kollmann K, Weisz E, et al
    JunB is a gatekeeper for B-lymphoid leukemia.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  50. WUERZBERGER-DAVIS SM , Nakamura Y, Seufzer BJ, Miyamoto S, et al
    NF-kappaB activation by combinations of NEMO SUMOylation and ATM activation stresses in the absence of DNA damage.
    Oncogene. 2007;26:641-51.
    PubMed     Related articles    Abstract available


    January 2007
  51. GARZON R , Pichiorri F, Palumbo T, Visentini M, et al
    MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  52. STREFFORD JC , Worley H, Barber K, Wright S, et al
    Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  53. FABRE C , Carvalho G, Tasdemir E, Braun T, et al
    NF-kappaB inhibition sensitizes to starvation-induced cell death in high-risk myelodysplastic syndrome and acute myeloid leukemia.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  54. OBEID D , Nguyen J, Lesavre P, Bauvois B, et al
    Differential regulation of tumor necrosis factor-alpha-converting enzyme and angiotensin-converting enzyme by type I and II interferons in human normal and leukemic myeloid cells.
    Oncogene. 2007;26:102-10.
    PubMed     Related articles    Abstract available


    December 2006
  55. FILOMENKO R , Prevotat L, Rebe C, Cortier M, et al
    Caspase-10 involvement in cytotoxic drug-induced apoptosis of tumor cells.
    Oncogene. 2006;25:7635-45.
    PubMed     Related articles    Abstract available


    November 2006
  56. BALKHI MY , Trivedi AK, Geletu M, Christopeit M, et al
    Proteomics of acute myeloid leukaemia: Cytogenetic risk groups differ specifically in their proteome, interactome and post-translational protein modifications.
    Oncogene. 2006;25:7041-58.
    PubMed     Related articles    Abstract available


    October 2006
  57. BILLOTTET C , Grandage VL, Gale RE, Quattropani A, et al
    A selective inhibitor of the p110delta isoform of PI 3-kinase inhibits AML cell proliferation and survival and increases the cytotoxic effects of VP16.
    Oncogene. 2006;25:6648-59.
    PubMed     Related articles    Abstract available


  58. HUANG Y , Zhao Q, Zhou CX, Gu ZM, et al
    Antileukemic roles of human phospholipid scramblase 1 gene, evidence from inducible PLSCR1-expressing leukemic cells.
    Oncogene. 2006;25:6618-27.
    PubMed     Related articles    Abstract available


  59. CARVALHO G , Fabre C, Braun T, Grosjean J, et al
    Inhibition of NEMO, the regulatory subunit of the IKK complex, induces apoptosis in high-risk myelodysplastic syndrome and acute myeloid leukemia.
    Oncogene. 2006;.
    PubMed     Related articles    Abstract available


  60. DUNNE J , Cullmann C, Ritter M, Soria NM, et al
    siRNA-mediated AML1/MTG8 depletion affects differentiation and proliferation-associated gene expression in t(8;21)-positive cell lines and primary AML blasts.
    Oncogene. 2006;25:6067-78.
    PubMed     Related articles    Abstract available


    September 2006
  61. MATHEW CG
    Fanconi anaemia genes and susceptibility to cancer.
    Oncogene. 2006;25:5875-84.
    PubMed     Related articles    Abstract available


  62. ARTUS C , Maquarre E, Moubarak RS, Delettre C, et al
    CD44 ligation induces caspase-independent cell death via a novel calpain/AIF pathway in human erythroleukemia cells.
    Oncogene. 2006;25:5741-51.
    PubMed     Related articles    Abstract available


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