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  Liver Diseases

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Articles published in Am J Pathol

Retrieve available abstracts of 48 articles:
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Single Articles


    October 2017
  1. WARNER DR, Liu H, Miller ME, Ramsden CE, et al
    Dietary Linoleic Acid and Its Oxidized Metabolites Exacerbate Liver Injury Caused by Ethanol via Induction of Hepatic Proinflammatory Response in Mice.
    Am J Pathol. 2017;187:2232-2245.
    PubMed     Text format     Abstract available



  2. This Month in AJP.
    Am J Pathol. 2017;187:2129.
    PubMed     Text format     Abstract available


    September 2017
  3. YAMAMOTO M, Xin B, Watanabe K, Ooshio T, et al
    Oncogenic determination of a broad spectrum of phenotypes of hepatocyte-derived mouse liver tumors.
    Am J Pathol. 2017 Sep 27. pii: S0002-9440(17)30174.
    PubMed     Text format     Abstract available


  4. CHOWDHARY V, Teng KY, Thakral S, Zhang B, et al
    miR-122 protects mice and human hepatocytes from acetaminophen toxicity by regulating CYP1A2 and CYP2E1 expression.
    Am J Pathol. 2017 Sep 26. pii: S0002-9440(17)30413.
    PubMed     Text format     Abstract available


  5. POZNIAK KN, Pearen MA, Pereira TN, Kramer CS, et al
    Taurocholate induces biliary differentiation of liver progenitor cells causing hepatic stellate cell chemotaxis in the Ductular Reaction: Role in pediatric cystic fibrosis liver disease.
    Am J Pathol. 2017 Sep 18. pii: S0002-9440(17)30375.
    PubMed     Text format     Abstract available


  6. LIU L, Zhang L, Zhang L, Yang F, et al
    Hepatic Tmem30a deficiency causes intrahepatic cholestasis by impairing expression and localization of bile salt transporters.
    Am J Pathol. 2017 Sep 14. pii: S0002-9440(17)30485.
    PubMed     Text format     Abstract available


  7. RANI R, Tandon A, Wang J, Kumar S, et al
    Stellate Cells Orchestrate Concanavalin A-Induced Acute Liver Damage.
    Am J Pathol. 2017;187:2008-2019.
    PubMed     Text format     Abstract available


    August 2017
  8. PULIGA E, Min Q, Tao J, Zhang R, et al
    Thyroid hormone receptor-beta agonist GC-1 inhibits Met-beta-catenin driven hepatocellular cancer.
    Am J Pathol. 2017 Aug 11. pii: S0002-9440(17)30403.
    PubMed     Text format     Abstract available


  9. JENA PK, Sheng L, Liu HX, Kalanetra KM, et al
    Western Diet-Induced Dysbiosis in Farnesoid X Receptor Knockout Mice Causes Persistent Hepatic Inflammation after Antibiotic Treatment.
    Am J Pathol. 2017;187:1800-1813.
    PubMed     Text format     Abstract available


  10. CHIANG JYL
    Linking Sex Differences in Non-Alcoholic Fatty Liver Disease to Bile Acid Signaling, Gut Microbiota, and High Fat Diet.
    Am J Pathol. 2017;187:1658-1659.
    PubMed     Text format     Abstract available


    July 2017
  11. KIKUCHI A, Pradhan-Sundd T, Singh S, Nagarajan S, et al
    Platelet-Derived Growth Factor Receptor Alpha Contributes to Human Hepatic Stellate Cell Proliferation and Migration.
    Am J Pathol. 2017 Jul 19. pii: S0002-9440(17)30329.
    PubMed     Text format     Abstract available


  12. LABGAA I, Stueck A, Ward SC
    Lymphoepithelioma-Like Carcinoma in Liver.
    Am J Pathol. 2017;187:1438-1444.
    PubMed     Text format     Abstract available


    June 2017
  13. GUILLAUME M, Handgraaf S, Fabre A, Raymond-Letron I, et al
    Selective Activation of Estrogen Receptor alpha Activation Function-1 Is Sufficient to Prevent Obesity, Steatosis, and Insulin Resistance in Mouse.
    Am J Pathol. 2017;187:1273-1287.
    PubMed     Text format     Abstract available


    May 2017
  14. KYRITSI K, Meng F, Zhou T, Wu N, et al
    Knockdown of Hepatic Gonadotropin-Releasing Hormone by Vivo-Morpholino Decreases Liver Fibrosis in Multidrug Resistance Gene 2 Knockout Mice by Down-Regulation of miR-200b.
    Am J Pathol. 2017 May 11. pii: S0002-9440(17)30044.
    PubMed     Text format     Abstract available


    April 2017
  15. KUMAR S, Wang J, Shanmukhappa SK, Gandhi CR, et al
    Toll-Like Receptor 4-Independent Carbon Tetrachloride-Induced Fibrosis and Lipopolysaccharide-Induced Acute Liver Injury in Mice: Role of Hepatic Stellate Cells.
    Am J Pathol. 2017 Apr 12. pii: S0002-9440(17)30128.
    PubMed     Text format     Abstract available


  16. CHENG S, Zou M, Liu Q, Kuang J, et al
    Activation of Constitutive Androstane Receptor Prevents Cholesterol Gallstone Formation.
    Am J Pathol. 2017;187:808-818.
    PubMed     Text format     Abstract available


    March 2017
  17. HU B, Li Y, Gao L, Guo Y, et al
    Hepatic Induction of Fatty Acid Binding Protein 4 Plays a Pathogenic Role in Sepsis in Mice.
    Am J Pathol. 2017 Mar 6. pii: S0002-9440(17)30194.
    PubMed     Text format     Abstract available


    February 2017
  18. HOLZER K, Drucker E, Roessler S, Dauch D, et al
    Proteomic Analysis Reveals GMP Synthetase as p53 Repression Target in Liver Cancer.
    Am J Pathol. 2017;187:228-235.
    PubMed     Text format     Abstract available


    January 2017
  19. YANG Z, Liu Y, Qin L, Wu P, et al
    Cathepsin H-Mediated Degradation of HDAC4 for Matrix Metalloproteinase Expression in Hepatic Stellate Cells: Implications of Epigenetic Suppression of Matrix Metalloproteinases in Fibrosis through Stabilization of Class IIa Histone Deacetylases.
    Am J Pathol. 2017 Jan 31. pii: S0002-9440(17)30022.
    PubMed     Text format     Abstract available


  20. STOCK P, Bielohuby M, Staege MS, Hsu MJ, et al
    Impairment of Host Liver Repopulation by Transplanted Hepatocytes in Aged Rats and the Release by Short-Term Growth Hormone Treatment.
    Am J Pathol. 2017 Jan 11. pii: S0002-9440(16)30543.
    PubMed     Text format     Abstract available


  21. BHUSHAN B, Poudel S, Manley MW Jr, Roy N, et al
    Inhibition of Glycogen Synthase Kinase 3 Accelerated Liver Regeneration after Acetaminophen-Induced Hepatotoxicity in Mice.
    Am J Pathol. 2017 Jan 6. pii: S0002-9440(16)30536.
    PubMed     Text format     Abstract available



  22. This Month in AJP.
    Am J Pathol. 2017;187:1.
    PubMed     Text format     Abstract available


  23. ELGILANI F, Mao SA, Glorioso JM, Yin M, et al
    Chronic Phenotype Characterization of a Large-Animal Model of Hereditary Tyrosinemia Type 1.
    Am J Pathol. 2017;187:33-41.
    PubMed     Text format     Abstract available


    December 2016
  24. RONIS M, Mercer K, Engi B, Pulliam C, et al
    Global Deletion of Glutathione S-Transferase A4 Exacerbates Developmental Nonalcoholic Steatohepatitis.
    Am J Pathol. 2016 Dec 17. pii: S0002-9440(16)30533.
    PubMed     Text format     Abstract available


    November 2016
  25. HUBEL E, Saroha A, Park WJ, Pewzner-Jung Y, et al
    Sortilin Deficiency Reduces Ductular Reaction, Hepatocyte Apoptosis, and Liver Fibrosis in Cholestatic-Induced Liver Injury.
    Am J Pathol. 2016 Nov 11. pii: S0002-9440(16)30408.
    PubMed     Text format     Abstract available


  26. WANG R, Ding Q, De Assuncao TM, Mounajjed T, et al
    Hepatic Stellate Cell Selective Disruption of Dynamin-2 GTPase Increases Murine Fibrogenesis through Up-Regulation of Sphingosine-1 Phosphate-Induced Cell Migration.
    Am J Pathol. 2016 Nov 10. pii: S0002-9440(16)30404.
    PubMed     Text format     Abstract available


    September 2016
  27. CHEN L, Chen R, Velazquez VM, Brigstock DR, et al
    Fibrogenic Signaling Is Suppressed in Hepatic Stellate Cells through Targeting of Connective Tissue Growth Factor (CCN2) by Cellular or Exosomal MicroRNA-199a-5p.
    Am J Pathol. 2016 Sep 20. pii: S0002-9440(16)30291.
    PubMed     Text format     Abstract available


  28. NI HM, McGill MR, Chao X, Woolbright BL, et al
    Caspase Inhibition Prevents Tumor Necrosis Factor-alpha-Induced Apoptosis and Promotes Necrotic Cell Death in Mouse Hepatocytes in Vivo and in Vitro.
    Am J Pathol. 2016 Sep 7. pii: S0002-9440(16)30236.
    PubMed     Text format     Abstract available


    July 2016
  29. VASSEUR P, Serres L, Jegou JF, Pohin M, et al
    High-Fat Diet-Induced IL-17A Exacerbates Psoriasiform Dermatitis in a Mouse Model of Steatohepatitis.
    Am J Pathol. 2016 Jul 13. pii: S0002-9440(16)30207.
    PubMed     Text format     Abstract available


    May 2016
  30. ANDRIQUE L, Poglio S, Prochazkova-Carlotti M, Kadin ME, et al
    Intrahepatic Xenograft of Cutaneous T-Cell Lymphoma Cell Lines: A Useful Model for Rapid Biological and Therapeutic Evaluation.
    Am J Pathol. 2016 May 12. pii: S0002-9440(16)30081.
    PubMed     Text format     Abstract available


  31. MIYAGAWA K, Oe S, Honma Y, Izumi H, et al
    Lipid-Induced Endoplasmic Reticulum Stress Impairs Selective Autophagy at the Step of Autophagosome-Lysosome Fusion in Hepatocytes.
    Am J Pathol. 2016 May 5. pii: S0002-9440(16)30062.
    PubMed     Text format     Abstract available


    April 2016
  32. ISAYAMA F, Moore S, Hines IH, Wheeler MD, et al
    Fas Regulates Macrophage Polarization and Fibrogenic Phenotype in a Model of Chronic Ethanol-Induced Hepatocellular Injury.
    Am J Pathol. 2016 Apr 18. pii: S0002-9440(16)30011.
    PubMed     Text format     Abstract available


  33. KIRPICH IA, Petrosino J, Ajami N, Feng W, et al
    Saturated and Unsaturated Dietary Fats Differentially Modulate Ethanol-Induced Changes in Gut Microbiome and Metabolome in a Mouse Model of Alcoholic Liver Disease.
    Am J Pathol. 2016;186:765-76.
    PubMed     Text format     Abstract available


    March 2016
  34. LUO P, Wang PX, Li ZZ, Zhang XJ, et al
    Hepatic Oncostatin M Receptor beta Regulates Obesity-Induced Steatosis and Insulin Resistance.
    Am J Pathol. 2016 Mar 11. pii: S0002-9440(16)00101.
    PubMed     Text format     Abstract available


  35. MERLIN S, Bhargava KK, Ranaldo G, Zanolini D, et al
    Kupffer Cell Transplantation in Mice for Elucidating Monocyte/Macrophage Biology and for Potential in Cell or Gene Therapy.
    Am J Pathol. 2016;186:539-51.
    PubMed     Text format     Abstract available


  36. HUANG J, Schriefer AE, Cliften PF, Dietzen D, et al
    Postponing the Hypoglycemic Response to Partial Hepatectomy Delays Mouse Liver Regeneration.
    Am J Pathol. 2016;186:587-99.
    PubMed     Text format     Abstract available


    February 2016
  37. FERRARIS P, Chandra PK, Panigrahi R, Aboulnasr F, et al
    Cellular Mechanism for Impaired Hepatitis C Virus Clearance by Interferon Associated with IFNL3 Gene Polymorphisms Relates to Intrahepatic Interferon-lambda Expression.
    Am J Pathol. 2016 Feb 16. pii: S0002-9440(16)00072.
    PubMed     Text format     Abstract available


  38. BHATTACHARYA S, Steele R, Shrivastava S, Chakraborty S, et al
    Serum miR-30e and miR-223 as Novel Noninvasive Biomarkers for Hepatocellular Carcinoma.
    Am J Pathol. 2016;186:242-7.
    PubMed     Text format     Abstract available


  39. MCMILLIN M, Frampton G, Quinn M, Ashfaq S, et al
    Bile Acid Signaling Is Involved in the Neurological Decline in a Murine Model of Acute Liver Failure.
    Am J Pathol. 2016;186:312-23.
    PubMed     Text format     Abstract available


    January 2016
  40. BOSCH M, Fajardo A, Alcala-Vida R, Fernandez-Vidal A, et al
    Hepatic Primary and Secondary Cholesterol Deposition and Damage in Niemann-Pick Disease.
    Am J Pathol. 2016 Jan 16. pii: S0002-9440(15)00693.
    PubMed     Text format     Abstract available


  41. MELINO M, Gadd VL, Alexander KA, Beattie L, et al
    Spatiotemporal Characterization of the Cellular and Molecular Contributors to Liver Fibrosis in a Murine Hepatotoxic-Injury Model.
    Am J Pathol. 2016 Jan 4. pii: S0002-9440(15)00659.
    PubMed     Text format     Abstract available


    December 2015
  42. QADIR XV, Chen W, Han C, Song K, et al
    miR-223 Deficiency Protects against Fas-Induced Hepatocyte Apoptosis and Liver Injury through Targeting Insulin-Like Growth Factor 1 Receptor.
    Am J Pathol. 2015;185:3141-51.
    PubMed     Text format     Abstract available


    November 2015
  43. OZAKI S, Vuyyuru R, Kageyama K, Terai M, et al
    Establishment and Characterization of Orthotopic Mouse Models for Human Uveal Melanoma Hepatic Colonization.
    Am J Pathol. 2015 Nov 21. pii: S0002-9440(15)00573.
    PubMed     Text format     Abstract available


  44. BENBOW JH, Thompson KJ, Cope HL, Brandon-Warner E, et al
    Diet-Induced Obesity Enhances Progression of Hepatocellular Carcinoma through Tenascin-C/Toll-Like Receptor 4 Signaling.
    Am J Pathol. 2015 Nov 18. pii: S0002-9440(15)00577.
    PubMed     Text format     Abstract available


    April 2015
  45. PENG H, Li TW, Yang H, Moyer MP, et al
    Methionine adenosyltransferase 2B-GIT1 complex serves as a scaffold to regulate Ras/Raf/MEK1/2 activity in human liver and colon cancer cells.
    Am J Pathol. 2015;185:1135-44.
    PubMed     Text format     Abstract available


  46. RAY D, Han Y, Franchitto A, DeMorrow S, et al
    Gonadotropin-releasing hormone stimulates biliary proliferation by paracrine/autocrine mechanisms.
    Am J Pathol. 2015;185:1061-72.
    PubMed     Text format     Abstract available


  47. CHEN W, Han C, Zhang J, Song K, et al
    Deletion of Mir155 prevents Fas-induced liver injury through up-regulation of Mcl-1.
    Am J Pathol. 2015;185:1033-44.
    PubMed     Text format     Abstract available


    March 2015
  48. MENG L, Quezada M, Levine P, Han Y, et al
    Functional role of cellular senescence in biliary injury.
    Am J Pathol. 2015;185:602-9.
    PubMed     Text format     Abstract available


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