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  Liver Diseases

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Articles published in Am J Pathol

Retrieve available abstracts of 58 articles:
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Single Articles


    February 2024
  1. NEWBERRY EP, Molitor EA, Liu A, Chong K, et al
    Impaired hepatic VLDL secretion promotes tumorigenesis and is accelerated with Fabp1 deletion.
    Am J Pathol. 2024 Feb 26:S0002-9440(24)00074.
    PubMed     Abstract available


  2. LIAN V, Hinrichs H, Young M, Faerber A, et al
    Maternal Obesogenic Diet Attenuates Microbiome-Dependent Offspring Weaning Reaction with Worsening of Steatotic Liver Disease.
    Am J Pathol. 2024;194:209-224.
    PubMed     Abstract available


  3. ABUDUYIMITI T, Goto H, Kimura K, Oshima Y, et al
    Diabetes accelerates steatohepatitis in mice: liver pathology and single-cell gene expression signatures.
    Am J Pathol. 2024 Feb 1:S0002-9440(24)00037-3. doi: 10.1016/j.ajpath.2024.
    PubMed     Abstract available


    December 2023
  4. TAN PK, Ostertag T, Rosenthal SB, Chilin-Fuentes D, et al
    Role of Hepatic Stellate and Liver Sinusoidal Endothelial Cells in a Human Primary Cell Three-Dimensional Model of Nonalcoholic Steatohepatitis.
    Am J Pathol. 2023 Dec 28:S0002-9440(23)00484.
    PubMed     Abstract available


  5. WEN T, Xie J, Ma L, Hao Z, et al
    Vitamin D receptor activation reduces hepatic inflammation via enhancing macrophage autophagy in cholestatic mice.
    Am J Pathol. 2023 Dec 15:S0002-9440(23)00462.
    PubMed     Abstract available


  6. JIANG C, Saiki Y, Hirota S, Iwata K, et al
    Ablation of Dual-Specificity Phosphatase 6 Protects against Nonalcoholic Fatty Liver Disease via Cytochrome P450 4A and Mitogen-Activated Protein Kinase.
    Am J Pathol. 2023;193:1988-2000.
    PubMed     Abstract available


  7. VENKATESAN N, Doskey LC, Malhi H
    The Role of Endoplasmic Reticulum in Lipotoxicity during Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Pathogenesis.
    Am J Pathol. 2023;193:1887-1899.
    PubMed     Abstract available


    November 2023
  8. WARNER JB, Hardesty JE, Song YL, Floyd AT, et al
    Hepatic Transcriptome and Its Regulation Following Soluble Epoxide Hydrolase Inhibition in Alcohol-Associated Liver Disease.
    Am J Pathol. 2023 Nov 2:S0002-9440(23)00410-8. doi: 10.1016/j.ajpath.2023.
    PubMed     Abstract available


    October 2023
  9. FENG R, Tong C, Lin T, Liu H, et al
    Insulin determines TGF-beta effects on HNF4alpha transcription in hepatocytes.
    Am J Pathol. 2023 Oct 9:S0002-9440(23)00365-6. doi: 10.1016/j.ajpath.2023.
    PubMed     Abstract available


  10. MAIERS JL, Chakraborty S
    The Cellular, Molecular, and Pathologic Consequences of Stress on the Liver.
    Am J Pathol. 2023;193:1353-1354.
    PubMed    


  11. ISMAIL A, Kennedy L, Francis H
    Sex-Dependent Differences in Cholestasis: Why Estrogen Signaling May Be a Key Pathophysiological Driver.
    Am J Pathol. 2023;193:1355-1362.
    PubMed     Abstract available


  12. BANERJEE P, Gaddam N, Chandler V, Chakraborty S, et al
    Oxidative Stress-Induced Liver Damage and Remodeling of the Liver Vasculature.
    Am J Pathol. 2023;193:1400-1414.
    PubMed     Abstract available


  13. JACKSON KG, Way GW, Zeng J, Lipp MK, et al
    The Dynamic Role of Endoplasmic Reticulum Stress in Chronic Liver Disease.
    Am J Pathol. 2023;193:1389-1399.
    PubMed     Abstract available


  14. ALI N, Ferrao K, Mehta KJ
    Liver Iron Loading in Alcohol-Associated Liver Disease.
    Am J Pathol. 2023;193:1427-1439.
    PubMed     Abstract available


    September 2023
  15. FITZGERALD H, Bonin JL, Khan S, Eid M, et al
    Resolvin D2-GPR18 Enhances Bone Marrow Function and Limits Steatosis and Hepatic Collagen Accumulation in Aging.
    Am J Pathol. 2023 Sep 15:S0002-9440(23)00322.
    PubMed     Abstract available


  16. TANAKA M, Jeong J, Thomas C, Zhang X, et al
    The sympathetic nervous system promotes hepatic lymphangiogenesis, which is protective against liver fibrosis.
    Am J Pathol. 2023 Sep 4:S0002-9440(23)00308-5. doi: 10.1016/j.ajpath.2023.
    PubMed     Abstract available


  17. CHAN KK, Au KY, Suen LH, Leung B, et al
    SORTILIN-DRIVEN CANCER SECRETOME ENHANCES TUMORIGENIC PROPERTIES OF HEPATOCELLULAR CARCINOMA VIA DE NOVO LIPOGENESIS.
    Am J Pathol. 2023 Sep 4:S0002-9440(23)00310-3. doi: 10.1016/j.ajpath.2023.
    PubMed     Abstract available


    August 2023
  18. MAIRINOJA L, Heikela H, Blom S, Kumar D, et al
    Deep Learning-Based Image Analysis of Liver Steatosis in Mouse Models.
    Am J Pathol. 2023;193:1072-1080.
    PubMed     Abstract available


    July 2023
  19. PANT K, Venugopal SK, Lorenzo Pisarello MJ, Gradilone SA, et al
    The Role of Gut Microbiome-Derived Short Chain Fatty Acid Butyrate in Hepatobiliary Diseases.
    Am J Pathol. 2023 Jul 6:S0002-9440(23)00238-9. doi: 10.1016/j.ajpath.2023.
    PubMed     Abstract available


  20. HANQUIER Z, Misra J, Baxter R, Maiers JL, et al
    Stress and Liver Fibrogenesis: Understanding the role and regulation of stress response pathways in Hepatic Stellate Cells.
    Am J Pathol. 2023 Jul 6:S0002-9440(23)00237-7. doi: 10.1016/j.ajpath.2023.
    PubMed     Abstract available


    June 2023
  21. CHEN PC, Hsu CP, Wang SY, Wu TY, et al
    miR-194 Up-Regulates Cholesterol 7 Alpha-Hydroxylase Expression via beta-Catenin Signaling and Aggravates Cholestatic Liver Diseases.
    Am J Pathol. 2023;193:755-768.
    PubMed     Abstract available


    May 2023
  22. CHEN Y, Pan Q, Liao W, Ai W, et al
    Transcription factor Foxo1 mediates TGF-beta1-induced apoptosis in hepatocytes.
    Am J Pathol. 2023 May 30:S0002-9440(23)00199.
    PubMed     Abstract available


    March 2023
  23. QIAN H, Ding WX
    SQSTM1/p62 and Hepatic Mallory Denk Body Formation in Alcohol-Associated Liver Disease.
    Am J Pathol. 2023 Mar 9:S0002-9440(23)00084-6. doi: 10.1016/j.ajpath.2023.
    PubMed     Abstract available


  24. HRNCIR HR, Hantelys F, Gracz AD
    Panic at the Bile Duct: How Intrahepatic Cholangiocytes Respond to Stress and Injury.
    Am J Pathol. 2023 Mar 2:S0002-9440(23)00063-9. doi: 10.1016/j.ajpath.2023.
    PubMed     Abstract available


    January 2023
  25. YUAN X, Bhat OM, Zou Y, Zhang Y, et al
    Contribution of Hepatic Steatosis-intensified Extracellular Vesicle Release to Aggravated Inflammatory Endothelial Injury in Liver-Specific Asah1 Gene Knockout Mice.
    Am J Pathol. 2023 Jan 10:S0002-9440(23)00001.
    PubMed     Abstract available


    November 2022
  26. SAPONARA E, Penno C, Orsini V, Wang ZY, et al
    Loss of Hepatic Lgr4 and Lgr5 Promotes Nonalcoholic Fatty Liver Disease.
    Am J Pathol. 2022 Nov 18:S0002-9440(22)00358.
    PubMed     Abstract available


  27. HURLEY EH, Tao J, Liu S, Krutsenko Y, et al
    Inhibition of HSF1 Signaling Decreases Hepatoblastoma Growth Via Induction of Apoptosis.
    Am J Pathol. 2022 Nov 3. pii: S0002-9440(22)00355.
    PubMed     Abstract available


    October 2022
  28. JABER FL, Sharma Y, Gupta S
    Hepatocyte Transplantation Rebalances Cytokines for Hepatic Regeneration in Rats with Ataxia Telangiectasia Mutated Pathway-Related Acute Liver Failure.
    Am J Pathol. 2022 Oct 27. pii: S0002-9440(22)00318.
    PubMed     Abstract available


  29. LUNA-MARCO C, Ubink A, Kopsida M, Heindryckx F, et al
    Endoplasmic Reticulum Stress and Metabolism in Hepatocellular Carcinoma.
    Am J Pathol. 2022 Oct 26. pii: S0002-9440(22)00322.
    PubMed     Abstract available


  30. ARGEMI J, Kedia K, Gritsenko MA, Clemente-Sanchez A, et al
    Integrated Transcriptomic and Proteomic Analysis Identifies Plasma Biomarkers of Hepatocellular Failure in Alcohol-Associated Hepatitis.
    Am J Pathol. 2022 Oct 13. pii: S0002-9440(22)00310.
    PubMed     Abstract available


    September 2022
  31. JIAO J, Jiang Y, Qian Y, Liu G, et al
    Expression of STING is increased in monocyte-derived macrophages and contributes to liver inflammation in hepatic ischemia-reperfusion injury.
    Am J Pathol. 2022 Sep 26. pii: S0002-9440(22)00285.
    PubMed     Abstract available


    August 2022
  32. DONG MP, Thanh Thuy LT, Hoang DV, Hai H, et al
    Soluble Immune Checkpoint Protein CD27 Is a Novel Prognostic Biomarker of Hepatocellular Carcinoma Development in Hepatitis C Virus-Sustained Virological Response Patients.
    Am J Pathol. 2022 Aug 11. pii: S0002-9440(22)00207.
    PubMed     Abstract available


    June 2022
  33. ROY N, Alencastro F, Roseman BA, Wilson SR, et al
    Dysregulation of Lipid and Glucose Homeostasis in Hepatocyte-Specific SLC25A34 Knockout Mice.
    Am J Pathol. 2022 Jun 16. pii: S0002-9440(22)00172.
    PubMed     Abstract available


  34. PHAM L, Kyritsi K, Zhou T, Ceci L, et al
    The Functional Roles of Immune Cells in Primary Liver Cancer.
    Am J Pathol. 2022;192:826-836.
    PubMed     Abstract available


    April 2022
  35. HARDESTY J, Day L, Warner J, Warner D, et al
    Hepatic protein and phosphoprotein signatures of alcohol-associated cirrhosis and hepatitis.
    Am J Pathol. 2022 Apr 28. pii: S0002-9440(22)00121.
    PubMed     Abstract available


  36. KORAL K, Bhushan B, Orr A, Stoops J, et al
    Lymphocyte specific protein 1 suppresses xenobiotic-induced CAR and subsequent YAP activated hepatocyte proliferation.
    Am J Pathol. 2022 Apr 4. pii: S0002-9440(22)00110.
    PubMed     Abstract available


    January 2022
  37. GOEL C, Monga SP, Nejak-Bowen K
    Role and Regulation of Wnt/beta-Catenin in Hepatic Perivenous Zonation and Physiological Homeostasis.
    Am J Pathol. 2022;192:4-17.
    PubMed     Abstract available


    December 2021
  38. RANI R, Sharma A, Wang J, Kumar S, et al
    Endotoxin-stimulated hepatic stellate cells augment acetaminophen-induced hepatocyte injury.
    Am J Pathol. 2021 Dec 23. pii: S0002-9440(21)00529.
    PubMed     Abstract available


  39. DIAO S, Tian Y, Hu W, Hou J, et al
    Weakly Supervised Framework for Cancer Regions Detection of Hepatocellular Carcinoma in Whole-Slide Pathologic Images Based on Multiscale Attention Convolutional Neural Network.
    Am J Pathol. 2021 Dec 9. pii: S0002-9440(21)00524.
    PubMed     Abstract available


  40. PETRESCU AD, Grant S, Williams E, An SY, et al
    Leptin Enhances Hepatic Fibrosis and Inflammation in a Mouse Model of Cholestasis.
    Am J Pathol. 2021 Dec 8. pii: S0002-9440(21)00523.
    PubMed     Abstract available


  41. ROY S, Banerjee P, Ekser B, Bayless K, et al
    Targeting Lymphangiogenesis and Lymph Node Metastasis in Liver Cancer.
    Am J Pathol. 2021;191:2052-2063.
    PubMed     Abstract available


    November 2021
  42. BATHULA CS, Chen J, Kumar R, Blackshear PJ, et al
    ZFP36L1 regulates Fgf21 mRNA turnover and modulates alcoholic hepatic steatosis and inflammation in mice.
    Am J Pathol. 2021 Nov 11. pii: S0002-9440(21)00478.
    PubMed     Abstract available


    October 2021
  43. CHAO X, Wang S, Hlobik M, Ballabio A, et al
    Loss of Hepatic Transcription Factor EB Attenuates Alcohol-Associated Liver Carcinogenesis.
    Am J Pathol. 2021 Oct 27. pii: S0002-9440(21)00442.
    PubMed     Abstract available


  44. ICHIMURA-SHIMIZU M, Tsuchiyama Y, Morimoto Y, Matsumoto M, et al
    A novel mouse model of non-alcoholic steatohepatitis suggests that liver fibrosis initiates around lipid-laden macrophages.
    Am J Pathol. 2021 Oct 25. pii: S0002-9440(21)00440.
    PubMed     Abstract available


  45. GOTTLIEB A, Dev S, DeVine L, Gabrielson KL, et al
    HEPATIC STEATOSIS IN THE MOUSE MODEL OF WILSON DISEASE COINCIDES WITH A MUTED INFLAMMATORY RESPONSE.
    Am J Pathol. 2021 Oct 7. pii: S0002-9440(21)00435.
    PubMed     Abstract available



  46. This Month in AJP.
    Am J Pathol. 2021;191:1669.
    PubMed    


    September 2021
  47. BARAJAS JM, Lin CH, Sun HL, Alencastro F, et al
    METTL3 Regulates Liver Homeostasis, Hepatocyte Ploidy, and Circadian Rhythm-Controlled Gene Expression in Mice.
    Am J Pathol. 2021 Sep 29. pii: S0002-9440(21)00430.
    PubMed     Abstract available



  48. This Month in AJP.
    Am J Pathol. 2021;191:1489.
    PubMed    


  49. LEE SW, Baek SM, Kang KK, Lee AR, et al
    Vitamin C Deficiency Inhibits Nonalcoholic Fatty Liver Disease Progression through Impaired de Novo Lipogenesis.
    Am J Pathol. 2021;191:1550-1563.
    PubMed     Abstract available


  50. MENG L, Goto M, Tanaka H, Kamikokura Y, et al
    Decreased Portal Circulation Augments Fibrosis and Ductular Reaction in Nonalcoholic Fatty Liver Disease in Mice.
    Am J Pathol. 2021;191:1580-1591.
    PubMed     Abstract available


    August 2021
  51. KANG MJ, Lee S, Jung U, Mandal C, et al
    Inhibition of hepatic stellate cell activation suppresses tumorigenicity of hepatocellular carcinoma in mice.
    Am J Pathol. 2021 Aug 21. pii: S0002-9440(21)00352.
    PubMed     Abstract available


    July 2021
  52. MATTHEWS DR, Li H, Zhou J, Li Q, et al
    Methionine- and Choline-deficient Diet-induced Non-alcoholic Steatohepatitis Is Associated with Increased Intestinal Inflammation.
    Am J Pathol. 2021 Jul 6. pii: S0002-9440(21)00302.
    PubMed     Abstract available


  53. BLOOMER SA, Brown KE
    Hepcidin and Iron Metabolism in Experimental Liver Injury.
    Am J Pathol. 2021;191:1165-1179.
    PubMed     Abstract available


    June 2021
  54. BAGLIERI J, Zhang C, Liang S, Liu X, et al
    Non-degradable collagen increases liver fibrosis but not hepatocellular carcinoma in mice.
    Am J Pathol. 2021 Jun 10. pii: S0002-9440(21)00254.
    PubMed     Abstract available


  55. WU MS, Kuo YP, Lo YC, Tsai DJ, et al
    Type I Interferon Signaling Accelerates Liver Regeneration by Metabolic Modulation in Noninfectious Conditions.
    Am J Pathol. 2021;191:1036-1048.
    PubMed     Abstract available


    May 2021
  56. CHEN Z, Jiang L, Liang L, Koral K, et al
    The Role of Fibroblast Growth Factor 19 in Hepatocellular Carcinoma.
    Am J Pathol. 2021 May 14. pii: S0002-9440(21)00198.
    PubMed     Abstract available


  57. ZHANG Y, Liang B, Song X, Wang H, et al
    Loss of Apc Cooperates with Activated Oncogenes to Induce Liver Tumor Formation in Mice.
    Am J Pathol. 2021;191:930-946.
    PubMed     Abstract available


    April 2021
  58. CHEN CY, Li Y, Zeng N, He L, et al
    Inhibition of estrogen related receptor alpha blocks liver steatosis and steatohepatitis and attenuates triglyceride biosynthesis.
    Am J Pathol. 2021 Apr 21. pii: S0002-9440(21)00162.
    PubMed     Abstract available


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