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Amedeo Prize 2008
The 21 Finalists


  Lung Cancer

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Articles published in Int J Cancer

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Single Articles


    May 2008
  1. ABE H , Kamai T, Shirataki H, Oyama T, et al
    High expression of Ran GTPase is associated with local invasion and metastasis of human clear cell renal cell carcinoma.
    Int J Cancer. 2008;122:2391-7.
    PubMed     Related articles    Abstract available


  2. SCHULZ S , Haussler U, Mandic R, Heverhagen JT, et al
    Treatment with ozone/oxygen-pneumoperitoneum results in complete remission of rabbit squamous cell carcinomas.
    Int J Cancer. 2008;122:2360-7.
    PubMed     Related articles    Abstract available


  3. LIU L , Xing D, Chen WR, Chen T, et al
    Calpain-mediated pathway dominates cisplatin-induced apoptosis in human lung adenocarcinoma cells as determined by real-time single cell analysis.
    Int J Cancer. 2008;122:2210-22.
    PubMed     Related articles    Abstract available


  4. REID A , Heyworth J, de Klerk NH, Musk B, et al
    Cancer incidence among women and girls environmentally and occupationally exposed to blue asbestos at Wittenoom, Western Australia.
    Int J Cancer. 2008;122:2337-44.
    PubMed     Related articles    Abstract available


  5. GLATT S , Halbauer D, Heindl S, Wernitznig A, et al
    hGPR87 contributes to viability of human tumor cells.
    Int J Cancer. 2008;122:2008-16.
    PubMed     Related articles    Abstract available


  6. SIESLING S , van der Aa MA, Coebergh JW, Pukkala E, et al
    Time-space trends in cancer incidence in the Netherlands in 1989-2003.
    Int J Cancer. 2008;122:2106-14.
    PubMed     Related articles    Abstract available


    April 2008
  7. RISCH A , Plass C
    Lung cancer epigenetics and genetics.
    Int J Cancer. 2008;123:1-7.
    PubMed     Related articles    Abstract available


  8. HEINLEIN C , Krepulat F, Lohler J, Speidel D, et al
    Mutant p53(R270H) gain of function phenotype in a mouse model for oncogene-induced mammary carcinogenesis.
    Int J Cancer. 2008;122:1701-9.
    PubMed     Related articles    Abstract available


  9. ALMEIDA GM , Duarte TL, Farmer PB, Steward WP, et al
    Multiple end-point analysis reveals cisplatin damage tolerance to be a chemoresistance mechanism in a NSCLC model: implications for predictive testing.
    Int J Cancer. 2008;122:1810-9.
    PubMed     Related articles    Abstract available


  10. GROZIO A , Paleari L, Catassi A, Servent D, et al
    Natural agents targeting the alpha7-nicotinic-receptor in NSCLC: a promising prospective in anti-cancer drug development.
    Int J Cancer. 2008;122:1911-5.
    PubMed     Related articles    Abstract available


  11. HO MY , Sun GH, Leu SJ, Ka SM, et al
    Combination of Fasl and GM-CSF confers synergistic antitumor immunity in an in vivo model of the murine Lewis lung carcinoma.
    Int J Cancer. 2008;.
    PubMed     Related articles    Abstract available


  12. LEE YC , Morgenstern H, Greenland S, Tashkin DP, et al
    A case-control study of the association of the polymorphisms and haplotypes of DNA ligase I with lung and upper-aerodigestive-tract cancers.
    Int J Cancer. 2008;122:1630-8.
    PubMed     Related articles    Abstract available


  13. YOSHIDA T , Okamoto I, Okabe T, Iwasa T, et al
    Matuzumab and cetuximab activate the epidermal growth factor receptor but fail to trigger downstream signaling by Akt or Erk.
    Int J Cancer. 2008;122:1530-8.
    PubMed     Related articles    Abstract available


    March 2008
  14. BARLESI F , Giaccone G, Gallegos-Ruiz MI, Span SW, et al
    Genotype analysis of the VNTR polymorphism in the SMYD3 histone methyltransferase gene: lack of correlation with the level of histone H3 methylation in NSCLC tissues or with the risk of NSCLC.
    Int J Cancer. 2008;122:1441-2.
    PubMed     Related articles   


  15. ISHIKAWA N , Hattori N, Yokoyama A, Tanaka S, et al
    Usefulness of monitoring the circulating Krebs von den Lungen-6 levels to predict the clinical outcome of patients with advanced nonsmall cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors.
    Int J Cancer. 2008;.
    PubMed     Related articles    Abstract available


    February 2008
  16. CHIEN CR , Chen TH
    Mean sojourn time and effectiveness of mortality reduction for lung cancer screening with computed tomography.
    Int J Cancer. 2008;.
    PubMed     Related articles    Abstract available


    January 2008
  17. LEE MW , Kim DS, Min NY, Kim HT, et al
    Akt1 inhibition by RNA interference sensitizes human non-small cell lung cancer cells to cisplatin.
    Int J Cancer. 2008;.
    PubMed     Related articles    Abstract available


  18. PERERA Y , Farina HG, Hernandez I, Mendoza O, et al
    Systemic administration of a peptide that impairs the protein kinase (CK2) phosphorylation reduces solid tumor growth in mice.
    Int J Cancer. 2008;122:57-62.
    PubMed     Related articles    Abstract available


  19. ZHENG Q , Safina A, Bakin AV
    Role of high-molecular weight tropomyosins in TGF-beta-mediated control of cell motility.
    Int J Cancer. 2008;122:78-90.
    PubMed     Related articles    Abstract available


    November 2007
  20. WHITEHURST B , Flister MJ, Bagaitkar J, Volk L, et al
    Anti-VEGF-A therapy reduces lymphatic vessel density and expression of VEGFR-3 in an orthotopic breast tumor model.
    Int J Cancer. 2007;121:2181-91.
    PubMed     Related articles    Abstract available


    October 2007
  21. CASTANO Z , Vergara-Irigaray N, Pajares MJ, Montuenga LM, et al
    Expression of alphaCP-4 inhibits cell cycle progression and suppresses tumorigenicity of lung cancer cells.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  22. CROSBIE PA , McGown G, Thorncroft MR, O'Donnell PN, et al
    Association between lung cancer risk and single nucleotide polymorphisms in the first intron and codon 178 of the DNA repair gene, O(6)-alkylguanine-DNA alkyltransferase.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  23. LIU G , Wheatley-Price P, Zhou W, Park S, et al
    Genetic polymorphisms of MDM2, cumulative cigarette smoking and nonsmall cell lung cancer risk.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  24. MATSUI J , Yamamoto Y, Funahashi Y, Tsuruoka A, et al
    E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  25. YAMASHITA M , Ino A, Kawabata K, Sakurai F, et al
    Expression of coxsackie and adenovirus receptor reduces the lung metastatic potential of murine tumor cells.
    Int J Cancer. 2007;121:1690-6.
    PubMed     Related articles    Abstract available


  26. CELIK Y
    6-(1-Oxobutyl)-5,8-dimethoxy-1,4-naphthoquinone inhibits lewis lung cancer by antiangiogenesis and apoptosis.
    Int J Cancer. 2007;.
    PubMed     Related articles   


  27. KURAHASHI N , Inoue M, Liu Y, Iwasaki M, et al
    Passive smoking and lung cancer in Japanese non-smoking women: A prospective study.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  28. LEAMON CP , Reddy JA, Vlahov IR, Westrick E, et al
    Comparative preclinical activity of the folate-targeted Vinca alkaloid conjugates EC140 and EC145.
    Int J Cancer. 2007;121:1585-92.
    PubMed     Related articles    Abstract available


    September 2007
  29. BECKERS T , Burkhardt C, Wieland H, Gimmnich P, et al
    Distinct pharmacological properties of second generation HDAC inhibitors with the benzamide or hydroxamate head group.
    Int J Cancer. 2007;121:1138-48.
    PubMed     Related articles    Abstract available


    August 2007
  30. RAMANAKUMAR AV , Parent ME, Latreille B, Siemiatycki J, et al
    Risk of lung cancer following exposure to carbon black, titanium dioxide and talc: Results from two case-control studies in Montreal.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  31. MAATTA AM , Liimatainen T, Wahlfors T, Wirth T, et al
    Evaluation of cancer virotherapy with attenuated replicative Semliki forest virus in different rodent tumor models.
    Int J Cancer. 2007;121:863-70.
    PubMed     Related articles    Abstract available


  32. WESARG E , Hoffarth S, Wiewrodt R, Kroll M, et al
    Targeting BCL-2 family proteins to overcome drug resistance in non-small cell lung cancer.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  33. FENNELL DA , Steele JP, Shamash J, Slater SE, et al
    Phase II trial of irinotecan, cisplatin and mitomycin for relapsed small cell lung cancer.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  34. MENVIELLE G , Kunst AE, Stirbu I, Borrell C, et al
    Socioeconomic inequalities in alcohol related cancer mortality among men: to what extent do they differ between Western European populations?
    Int J Cancer. 2007;121:649-55.
    PubMed     Related articles    Abstract available


    July 2007
  35. KAWANO H , Nishikawa M, Mitsui M, Takahashi Y, et al
    Improved anti-cancer effect of interferon gene transfer by sustained expression using CpG-reduced plasmid DNA.
    Int J Cancer. 2007;121:401-6.
    PubMed     Related articles    Abstract available


  36. GONDOS A , Arndt V, Holleczek B, Stegmaier C, et al
    Cancer survival in Germany and the United States at the beginning of the 21st century: an up-to-date comparison by period analysis.
    Int J Cancer. 2007;121:395-400.
    PubMed     Related articles    Abstract available


    June 2007
  37. YANG H , Spitz MR, Stewart DJ, Lu C, et al
    ATM sequence variants associate with susceptibility to non-small cell lung cancer.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  38. DUA P , Ingle A, Gude RP
    Suramin augments the antitumor and antimetastatic activity of pentoxifylline in B16F10 melanoma.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  39. INATA J , Hattori N, Yokoyama A, Ohshimo S, et al
    Circulating KL-6/MUC1 mucin carrying sialyl Lewisa oligosaccharide is an independent prognostic factor in patients with lung adenocarcinoma.
    Int J Cancer. 2007;120:2643-9.
    PubMed     Related articles    Abstract available


  40. COMTESSE N , Keller A, Diesinger I, Bauer C, et al
    Frequent overexpression of the genes FXR1, CLAPM1 and EIF4G located on amplicon 3q26-27 in squamous cell carcinoma of the lung.
    Int J Cancer. 2007;120:2538-44.
    PubMed     Related articles    Abstract available


  41. WU X , Lin J, Etzel CJ, Dong Q, et al
    Interplay between mutagen sensitivity and epidemiological factors in modulatinglung cancer risk.
    Int J Cancer. 2007;120:2687-95.
    PubMed     Related articles    Abstract available


  42. LOFT S , Svoboda P, Kasai H, Tjonneland A, et al
    Prospective study of urinary excretion of 7-methylguanine and the risk of lung cancer: Effect modification by mu class glutathione-S-transferases.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


    May 2007
  43. SOH J , Toyooka S, Ichihara S, Fujiwara Y, et al
    Impact of HER2 and EGFR gene status on gefitinib-treated patients with nonsmall-cell lung cancer.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  44. LINSEISEN J , Rohrmann S, Miller AB, Bueno-de-Mesquita HB, et al
    Fruit and vegetable consumption and lung cancer risk: Updated information from the European Prospective Investigation into Cancer and Nutrition (EPIC).
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  45. LANTUEJOUL S , Salon C, Soria JC, Brambilla E, et al
    Telomerase expression in lung preneoplasia and neoplasia.
    Int J Cancer. 2007;120:1835-41.
    PubMed     Related articles    Abstract available


    April 2007
  46. TAKENAKA T , Yoshino I, Kouso H, Ohba T, et al
    Combined evaluation of Rad51 and ERCC1 expressions for sensitivity to platinum agents in non-small cell lung cancer.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  47. CHEN Y , Pacyna-Gengelbach M, Deutschmann N, Niesporek S, et al
    Homeobox gene HOP has a potential tumor suppressive activity in human lung cancer.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  48. MERNITZ H , Smith DE, Wood RJ, Russell RM, et al
    Inhibition of lung carcinogenesis by 1alpha,25-dihydroxyvitamin D3 and 9-cis retinoic acid in the A/J mouse model: evidence of retinoid mitigation of vitamin D toxicity.
    Int J Cancer. 2007;120:1402-9.
    PubMed     Related articles    Abstract available


    March 2007
  49. LEVI F , Bosetti C, Fernandez E, Hill C, et al
    Trends in lung cancer among young European women: The rising epidemic in France and Spain.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  50. KO HM , Kang JH, Jung B, Kim HA, et al
    Critical role for matrix metalloproteinase-9 in platelet-activating factor-induced experimental tumor metastasis.
    Int J Cancer. 2007;120:1277-83.
    PubMed     Related articles    Abstract available


  51. PEREIRA MA , Tao L, Liu Y, Li L, et al
    Modulation by budesonide of DNA methylation and mRNA expression in mouse lung tumors.
    Int J Cancer. 2007;120:1150-3.
    PubMed     Related articles    Abstract available


  52. SUGAYA M , Takenoyama M, Shigematsu Y, Baba T, et al
    Identification of HLA-A24 restricted shared antigen recognized by autologous cytotoxic T lymphocytes from a patient with large cell carcinoma of the lung.
    Int J Cancer. 2007;120:1055-62.
    PubMed     Related articles    Abstract available


    February 2007
  53. LEE HJ , Lee HJ, Song GY, Li G, et al
    6-(1-Oxobutyl)-5,8-dimethoxy-1,4-naphthoquinone inhibits lewis lung cancer by antiangiogenesis and apoptosis.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  54. HONG KM , Yang SH, Chowdhuri SR, Player A, et al
    Inactivation of LLC1 gene in nonsmall cell lung cancer.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  55. GORLOVA OY , Weng SF, Zhang Y, Amos CI, et al
    Aggregation of cancer among relatives of never-smoking lung cancer patients.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  56. BLOOM GC , Eschrich S, Zhou JX, Coppola D, et al
    Elucidation of a protein signature discriminating six common types of adenocarcinoma.
    Int J Cancer. 2007;120:769-75.
    PubMed     Related articles    Abstract available


  57. ZHANG H , Yang YC, Zhang L, Fan J, et al
    Dimeric ansamycins--a new class of antitumor Hsp90 modulators with prolonged inhibitory activity.
    Int J Cancer. 2007;120:918-26.
    PubMed     Related articles    Abstract available


  58. KABAT GC , Miller AB, Rohan TE
    Reproductive and hormonal factors and risk of lung cancer in women: A prospective cohort study.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  59. KIM Y , Lian F, Yeum KJ, Chongviriyaphan N, et al
    The effects of combined antioxidant (beta-carotene, alpha-tocopherol and ascorbic acid) supplementation on antioxidant capacity, DNA single-strand breaks and levels of insulin-like growth factor-1/IGF-binding protein 3 in the ferret model of lung canc
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  60. HOLMES MD , Murin S, Chen WY, Kroenke CH, et al
    Smoking and survival after breast cancer diagnosis.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


    January 2007
  61. WANG HW , Lin CP, Chiu JH, Chow KC, et al
    Reversal of inflammation-associated dihydrodiol dehydrogenases (AKR1C1 and AKR1C2) overexpression and drug resistance in nonsmall cell lung cancer cells by wogonin and chrysin.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  62. NAWROT TS , Nackaerts K, Hoet PH, Nemery B, et al
    Lung cancer mortality and fine particulate air pollution in Europe.
    Int J Cancer. 2007;.
    PubMed     Related articles   


  63. MA ES , Wong CL, Siu D, Chan WK, et al
    Amplification, mutation and loss of heterozygosity of the EGFR gene in metastatic lung cancer.
    Int J Cancer. 2007;.
    PubMed     Related articles   


  64. GILLE J , Heidenreich R, Pinter A, Schmitz J, et al
    Simultaneous blockade of VEGFR-1 and VEGFR-2 activation is necessary to efficiently inhibit experimental melanoma growth and metastasis formation.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  65. HERNANDEZ-DIAZ S , Garcia Rodriguez LA
    Nonsteroidal anti-inflammatory drugs and risk of lung cancer.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


  66. JUDDE JG , Rebucci M, Vogt N, de Cremoux P, et al
    Gefitinib and chemotherapy combination studies in five novel human non small cell lung cancer xenografts. Evidence linking EGFR signaling to gefitinib antitumor response.
    Int J Cancer. 2007;.
    PubMed     Related articles    Abstract available


    December 2006
  67. ICHIHARA S , Toyooka S, Fujiwara Y, Hotta K, et al
    The impact of epidermal growth factor receptor gene status on gefitinib-treated Japanese patients with non-small-cell lung cancer.
    Int J Cancer. 2006;.
    PubMed     Related articles    Abstract available


  68. NGO CV , Picha K, McCabe F, Millar H, et al
    CNTO 859, a humanized anti-tissue factor monoclonal antibody, is a potent inhibitor of breast cancer metastasis and tumor growth in xenograft models.
    Int J Cancer. 2006;.
    PubMed     Related articles    Abstract available


  69. MORI A , Sakurai H, Choo MK, Obi R, et al
    Severe pulmonary metastasis in obese and diabetic mice.
    Int J Cancer. 2006;119:2760-7.
    PubMed     Related articles    Abstract available


  70. JEONG EG , Soung YH, Lee JW, Lee SH, et al
    ERBB3 kinase domain mutations are rare in lung, breast and colon carcinomas.
    Int J Cancer. 2006;119:2986-7.
    PubMed     Related articles   


  71. MONZAVI-KARBASSI B , Stanley JS, Hennings L, Jousheghany F, et al
    Chondroitin sulfate glycosaminoglycans as major P-selectin ligands on metastatic breast cancer cell lines.
    Int J Cancer. 2006;.
    PubMed     Related articles    Abstract available


  72. TANG M , Torres-Lanzas J, Lopez-Rios F, Esteller M, et al
    Wnt signaling promoter hypermethylation distinguishes lung primary adenocarcinomas from colorectal metastasis to the lung.
    Int J Cancer. 2006;119:2603-6.
    PubMed     Related articles    Abstract available


  73. BUTTITTA F , Barassi F, Fresu G, Felicioni L, et al
    Mutational analysis of the HER2 gene in lung tumors from Caucasian patients: mutations are mainly present in adenocarcinomas with bronchioloalveolar features.
    Int J Cancer. 2006;119:2586-91.
    PubMed     Related articles    Abstract available


    November 2006
  74. MAHABIR S , Spitz MR, Barrera SL, Beaver SH, et al
    Dietary zinc, copper and selenium, and risk of lung cancer.
    Int J Cancer. 2006;.
    PubMed     Related articles    Abstract available


  75. VAN IERSEL CA , de Koning HJ, Draisma G, Mali WP, et al
    Risk-based selection from the general population in a screening trial: Selection criteria, recruitment and power for the Dutch-Belgian randomised lung cancer multi-slice CT screening trial (NELSON).
    Int J Cancer. 2006;.
    PubMed     Related articles    Abstract available


  76. PARK YP , Choi SC, Kim JH, Song EY, et al
    Up-regulation of Mac-2 binding protein by hTERT in gastric cancer.
    Int J Cancer. 2006;.
    PubMed     Related articles    Abstract available


  77. BISOFFI M , Heaphy CM, Griffith JK
    Telomeres: prognostic markers for solid tumors.
    Int J Cancer. 2006;119:2255-60.
    PubMed     Related articles    Abstract available


  78. SATO N , Fukui T, Taniguchi T, Yokoyama T, et al
    RhoB is frequently downregulated in non-small-cell lung cancer and resides in the 2p24 homozygous deletion region of a lung cancer cell line.
    Int J Cancer. 2006;.
    PubMed     Related articles    Abstract available


    October 2006
  79. HIRAI K , Sasahira T, Ohmori H, Fujii K, et al
    Inhibition of heme oxygenase-1 by zinc protoporphyrin IX reduces tumor growth of LL/2 lung cancer in C57BL mice.
    Int J Cancer. 2006;.
    PubMed     Related articles    Abstract available


  80. GROEPER C , Gambazzi F, Zajac P, Bubendorf L, et al
    Cancer/testis antigen expression and specific cytotoxic T lymphocyte responses in non small cell lung cancer.
    Int J Cancer. 2006;.
    PubMed     Related articles    Abstract available


  81. CASSIDY A , Duffy SW, Myles JP, Liloglou T, et al
    Lung cancer risk prediction: A tool for early detection.
    Int J Cancer. 2006;.
    PubMed     Related articles    Abstract available


  82. RUNDLE A DR PH
    Letter to the editor, re "Bulky DNA adducts as risk indicators of lung cancer in a Danish case-cohort study"
    Int J Cancer. 2006;.
    PubMed     Related articles   


  83. YU IT , Tse LA
    Exploring the joint effects of silicosis and smoking on lung cancer risks.
    Int J Cancer. 2006;.
    PubMed     Related articles    Abstract available


  84. RAASCHOU-NIELSEN O , Thomsen BL, Overvad K, Tjonneland A, et al
    Bulky DNA adducts as risk indicators of lung cancer in a Danish case-cohort study.
    Int J Cancer. 2006;.
    PubMed     Related articles   


  85. CANTOR JP , Iliopoulos D, Rao AS, Druck T, et al
    Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity.
    Int J Cancer. 2006;.
    PubMed     Related articles    Abstract available


    March 2006
  86. AL-WADEI HA , Takahashi T, Schuller HM
    Growth stimulation of human pulmonary adenocarcinoma cells and small airway epithelial cells by beta-carotene via activation of cAMP, PKA, CREB and ERK1/2.
    Int J Cancer. 2006;118:1370-80.
    PubMed     Related articles    Abstract available


  87. TOYOOKA S , Yatabe Y, Tokumo M, Ichimura K, et al
    Mutations of epidermal growth factor receptor and K-ras genes in adenosquamous carcinoma of the lung.
    Int J Cancer. 2006;118:1588-90.
    PubMed     Related articles   


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