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  Lung Cancer

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Articles published in Int J Oncol

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Single Articles


    May 2017
  1. WANG C, Chen K, Liao S, Gu W, et al
    The flightless I protein interacts with RNA-binding proteins and is involved in the genome-wide mRNA post-transcriptional regulation in lung carcinoma cells.
    Int J Oncol. 2017 May 11. doi: 10.3892/ijo.2017.3995.
    PubMed     Text format     Abstract available


  2. UJIIE H, Kato T, Lee D, Hu HP, et al
    Overexpression of MAGEA2 has a prognostic significance and is a potential therapeutic target for patients with lung cancer.
    Int J Oncol. 2017 May 5. doi: 10.3892/ijo.2017.3984.
    PubMed     Text format     Abstract available


    April 2017
  3. SHI B, Wang LF, Meng WS, Chen L, et al
    Carnosic acid and fisetin combination therapy enhances inhibition of lung cancer through apoptosis induction.
    Int J Oncol. 2017 Apr 20. doi: 10.3892/ijo.2017.3970.
    PubMed     Text format     Abstract available


  4. LIU C, Lv D, Li M, Zhang X, et al
    Hypermethylation of miRNA-589 promoter leads to upregulation of HDAC5 which promotes malignancy in non-small cell lung cancer.
    Int J Oncol. 2017 Apr 20. doi: 10.3892/ijo.2017.3967.
    PubMed     Text format     Abstract available


    March 2017
  5. YAMAMOTO G, Kikuchi M, Kobayashi S, Arai Y, et al
    Routine genetic testing of lung cancer specimens derived from surgery, bronchoscopy and fluid aspiration by next generation sequencing.
    Int J Oncol. 2017 Mar 27. doi: 10.3892/ijo.2017.3935.
    PubMed     Text format     Abstract available


  6. TAN Q, Zuo J, Qiu S, Yu Y, et al
    Identification of circulating long non-coding RNA GAS5 as a potential biomarker for non-small cell lung cancer diagnosisnon-small cell lung cancer, long non-coding RNA, plasma, GAS5, biomarker.
    Int J Oncol. 2017 Mar 22. doi: 10.3892/ijo.2017.3925.
    PubMed     Text format     Abstract available


    February 2017
  7. YANG X, Han M, Han H, Wang B, et al
    Silencing Snail suppresses tumor cell proliferation and invasion by reversing epithelial-to-mesenchymal transition and arresting G2/M phase in non-small cell lung cancer.
    Int J Oncol. 2017 Feb 21. doi: 10.3892/ijo.2017.3888.
    PubMed     Text format     Abstract available


  8. SRINUAL S, Chanvorachote P, Pongrakhananon V
    Suppression of cancer stem-like phenotypes in NCI-H460 lung cancer cells by vanillin through an Akt-dependent pathway.
    Int J Oncol. 2017 Feb 17. doi: 10.3892/ijo.2017.3879.
    PubMed     Text format     Abstract available


  9. XIONG Y, Wang M, Zhao J, Wang L, et al
    SIRT3 is correlated with the malignancy of non-small cell lung cancer.
    Int J Oncol. 2017 Feb 2. doi: 10.3892/ijo.2017.3868.
    PubMed     Text format     Abstract available


  10. SCHNEIDER MA, Christopoulos P, Muley T, Warth A, et al
    AURKA, DLGAP5, TPX2, KIF11 and CKAP5: Five specific mitosis-associated genes correlate with poor prognosis for non-small cell lung cancer patients.
    Int J Oncol. 2017;50:365-372.
    PubMed     Text format     Abstract available


  11. KANG H, Zhang J, Wang B, Liu M, et al
    Puerarin inhibits M2 polarization and metastasis of tumor-associated macrophages from NSCLC xenograft model via inactivating MEK/ERK 1/2 pathway.
    Int J Oncol. 2017;50:545-554.
    PubMed     Text format     Abstract available


  12. CHEN L, Wang L, Yan J, Ma C, et al
    131I-labeled monoclonal antibody targeting neuropilin receptor type-2 for tumor SPECT imaging.
    Int J Oncol. 2017;50:649-659.
    PubMed     Text format     Abstract available


    January 2017
  13. RUI Y, Peng WJ, Wang M, Wang Q, et al
    HIST1H3D: A promising therapeutic target for lung cancer.
    Int J Oncol. 2017 Jan 19. doi: 10.3892/ijo.2017.3856.
    PubMed     Text format     Abstract available


  14. LEE S, Matsuzaki H, Maeda M, Yamamoto S, et al
    Accelerated cell cycle progression of human regulatory T cell-like cell line caused by continuous exposure to asbestos fibers.
    Int J Oncol. 2017;50:66-74.
    PubMed     Text format     Abstract available


    December 2016
  15. CAO K, Pan Y, Yu L, Shu X, et al
    Monoclonal antibodies targeting non-small cell lung cancer stem-like cells by multipotent cancer stem cell monoclonal antibody library.
    Int J Oncol. 2016 Dec 22. doi: 10.3892/ijo.2016.3818.
    PubMed     Text format     Abstract available


  16. TU Z, Xie S, Xiong M, Liu Y, et al
    CXCR4 is involved in CD133-induced EMT in non-small cell lung cancer.
    Int J Oncol. 2016 Dec 19. doi: 10.3892/ijo.2016.3812.
    PubMed     Text format     Abstract available


  17. ABDELBASET-ISMAIL A, Pedziwiatr D, Schneider G, Niklinski J, et al
    Pituitary sex hormones enhance the prometastatic potential of human lung cancer cells by downregulating the intracellular expression of heme oxygenase1.
    Int J Oncol. 2016 Dec 2. doi: 10.3892/ijo.2016.3787.
    PubMed     Text format     Abstract available


  18. IM M, Kim A, Ma JY
    Ethanol extract of baked Gardeniae Fructus exhibits in vitro and in vivo anti-metastatic and anti-angiogenic activities in malignant cancer cells: Role of suppression of the NF-kappaB and HIF-1alpha pathways.
    Int J Oncol. 2016;49:2377-2386.
    PubMed     Text format     Abstract available


  19. KATO T, Lee D, Wu L, Patel P, et al
    SORORIN and PLK1 as potential therapeutic targets in malignant pleural mesothelioma.
    Int J Oncol. 2016;49:2411-2420.
    PubMed     Text format     Abstract available


  20. HWANG SJ, Park HG, Park Y, Lee HJ, et al
    An alpha-quaternary chiral latam derivative, YH-304 as a novel broad-spectrum anticancer agent.
    Int J Oncol. 2016;49:2480-2486.
    PubMed     Text format     Abstract available


    November 2016
  21. XU Z, Mei J, Tan Y
    Baicalin attenuates DDP (cisplatin) resistance in lung cancer by downregulating MARK2 and p-Akt.
    Int J Oncol. 2016 Nov 15. doi: 10.3892/ijo.2016.3768.
    PubMed     Text format     Abstract available


  22. KUMAMOTO T, Seki N, Mataki H, Mizuno K, et al
    Regulation of TPD52 by antitumor microRNA-218 suppresses cancer cell migration and invasion in lung squamous cell carcinoma.
    Int J Oncol. 2016;49:1870-1880.
    PubMed     Text format     Abstract available


    October 2016
  23. CHIBA M, Togashi Y, Tomida S, Mizuuchi H, et al
    MEK inhibitors against MET-amplified non-small cell lung cancer.
    Int J Oncol. 2016 Oct 17. doi: 10.3892/ijo.2016.3736.
    PubMed     Text format     Abstract available


  24. WANG Z, Xu W, Lin Z, Li C, et al
    Reduced apurinic/apyrimidinic endonuclease activity enhances the antitumor activity of oxymatrine in lung cancer cells.
    Int J Oncol. 2016 Oct 14. doi: 10.3892/ijo.2016.3734.
    PubMed     Text format     Abstract available


  25. JEON YJ, Bang W, Cho JH, Lee RH, et al
    Kahweol induces apoptosis by suppressing BTF3 expression through the ERK signaling pathway in non-small cell lung cancer cells.
    Int J Oncol. 2016 Oct 12. doi: 10.3892/ijo.2016.3727.
    PubMed     Text format     Abstract available


  26. HE Y, Zhang X, Wang L, Tian Z, et al
    Detection of cancer specific mutations in early-stage non-small cell lung cancer using cell-free DNA by targeted sequencing.
    Int J Oncol. 2016 Oct 12. doi: 10.3892/ijo.2016.3731.
    PubMed     Text format     Abstract available


  27. ZHOU H, Li J, Zhang Z, Ye R, et al
    RING1 and YY1 binding protein suppresses breast cancer growth and metastasis.
    Int J Oncol. 2016 Oct 5. doi: 10.3892/ijo.2016.3718.
    PubMed     Text format     Abstract available


  28. TANAKA T, Imamura T, Yoneda M, Irie A, et al
    Enhancement of active MMP release and invasive activity of lymph node metastatic tongue cancer cells by elevated signaling via the TNF-alpha-TNFR1-NF-kappaB pathway and a possible involvement of angiopoietin-like 4 in lung metastasis.
    Int J Oncol. 2016;49:1377-84.
    PubMed     Text format     Abstract available


  29. NOGIMORI K, Hori T, Kawaguchi K, Fukui T, et al
    Increased expression levels of ppGalNAc-T13 in lung cancers: Significance in the prognostic diagnosis.
    Int J Oncol. 2016;49:1369-76.
    PubMed     Text format     Abstract available


  30. QIN S, Yang C, Zhang B, Li X, et al
    XIAP inhibits mature Smac-induced apoptosis by degrading it through ubiquitination in NSCLC.
    Int J Oncol. 2016;49:1289-96.
    PubMed     Text format     Abstract available


    September 2016
  31. CZARNECKA KH, Migdalska-Sek M, Domanska D, Pastuszak-Lewandoska D, et al
    FHIT promoter methylation status, low protein and high mRNA levels in patients with non-small cell lung cancer.
    Int J Oncol. 2016;49:1175-84.
    PubMed     Text format     Abstract available


  32. YAMADA H, Takeda T, Michiue H, Abe T, et al
    Actin bundling by dynamin 2 and cortactin is implicated in cell migration by stabilizing filopodia in human non-small cell lung carcinoma cells.
    Int J Oncol. 2016;49:877-86.
    PubMed     Text format     Abstract available


  33. KIM JS, Kang SJ, Jeong HY, Kim MW, et al
    Anti-EGFR immunonanoparticles containing IL12 and salmosin genes for targeted cancer gene therapy.
    Int J Oncol. 2016;49:1130-8.
    PubMed     Text format     Abstract available


  34. ZHONG N, Shi S, Wang H, Wu G, et al
    Silencing Aurora-A with siRNA inhibits cell proliferation in human lung adenocarcinoma cells.
    Int J Oncol. 2016;49:1028-38.
    PubMed     Text format     Abstract available


    August 2016
  35. XU SW, Law BY, Mok SW, Leung EL, et al
    Autophagic degradation of epidermal growth factor receptor in gefitinib-resistant lung cancer by celastrol.
    Int J Oncol. 2016 Aug 3. doi: 10.3892/ijo.2016.3644.
    PubMed     Text format     Abstract available


  36. ZENG Y, Zhu J, Shen D, Qin H, et al
    Repression of Smad4 by miR205 moderates TGF-beta-induced epithelial-mesenchymal transition in A549 cell lines.
    Int J Oncol. 2016;49:700-8.
    PubMed     Text format     Abstract available


    July 2016
  37. HUANG T, She K, Peng G, Wang W, et al
    MicroRNA-186 suppresses cell proliferation and metastasis through targeting MAP3K2 in non-small cell lung cancer.
    Int J Oncol. 2016 Jul 29. doi: 10.3892/ijo.2016.3637.
    PubMed     Text format     Abstract available


  38. ZHANG N, Zeng Y, Du W, Zhu J, et al
    The EGFR pathway is involved in the regulation of PD-L1 expression via the IL-6/JAK/STAT3 signaling pathway in EGFR-mutated non-small cell lung cancer.
    Int J Oncol. 2016 Jul 26. doi: 10.3892/ijo.2016.3632.
    PubMed     Text format     Abstract available


  39. XIA H, Li Y, Lv X
    MicroRNA-107 inhibits tumor growth and metastasis by targeting the BDNF-mediated PI3K/AKT pathway in human non-small lung cancer.
    Int J Oncol. 2016 Jul 25. doi: 10.3892/ijo.2016.3628.
    PubMed     Text format     Abstract available


  40. PUCHSAKA P, Chaotham C, Chanvorachote P
    alpha-Lipoic acid sensitizes lung cancer cells to chemotherapeutic agents and anoikis via integrin beta1/beta3 downregulation.
    Int J Oncol. 2016 Jul 18. doi: 10.3892/ijo.2016.3624.
    PubMed     Text format     Abstract available


  41. CHEN M, Guo Y, Zhao R, Wang X, et al
    Ophiopogonin B induces apoptosis, mitotic catastrophe and autophagy in A549 cells.
    Int J Oncol. 2016;49:316-24.
    PubMed     Text format     Abstract available


    June 2016
  42. YANG X, Tietje AH, Yu X, Wei Y, et al
    Mouse interleukin-12/FasTI: A novel bi-functional fusion protein for cancer immuno/gene therapy.
    Int J Oncol. 2016;48:2381-6.
    PubMed     Text format     Abstract available


  43. WU D, Mou YP, Chen K, Cai JQ, et al
    Aldehyde dehydrogenase 3A1 is robustly upregulated in gastric cancer stem-like cells and associated with tumorigenesis.
    Int J Oncol. 2016 Jun 1. doi: 10.3892/ijo.2016.3551.
    PubMed     Text format     Abstract available


    May 2016
  44. KWON YS, Lee KS, Chun SY, Jang TJ, et al
    Suppressive effects of a proton beam on tumor growth and lung metastasis through the inhibition of metastatic gene expression in 4T1 orthotopic breast cancer model.
    Int J Oncol. 2016 May 13. doi: 10.3892/ijo.2016.3520.
    PubMed     Text format     Abstract available


  45. KURIMOTO R, Iwasawa S, Ebata T, Ishiwata T, et al
    Drug resistance originating from a TGF-beta/FGF-2-driven epithelial-to-mesenchymal transition and its reversion in human lung adenocarcinoma cell lines harboring an EGFR mutation.
    Int J Oncol. 2016;48:1825-36.
    PubMed     Text format     Abstract available


  46. HAN J, Zhao F, Zhang J, Zhu H, et al
    miR-223 reverses the resistance of EGFR-TKIs through IGF1R/PI3K/Akt signaling pathway.
    Int J Oncol. 2016;48:1855-67.
    PubMed     Text format     Abstract available


    April 2016
  47. MARCUS MW, Raji OY, Duffy SW, Young RP, et al
    Incorporating epistasis interaction of genetic susceptibility single nucleotide polymorphisms in a lung cancer risk prediction model.
    Int J Oncol. 2016 Apr 25. doi: 10.3892/ijo.2016.3499.
    PubMed     Text format     Abstract available


  48. XIAO X, He Z, Cao W, Cai F, et al
    Oridonin inhibits gefitinib-resistant lung cancer cells by suppressing EGFR/ERK/MMP-12 and CIP2A/Akt signaling pathways.
    Int J Oncol. 2016 Apr 15. doi: 10.3892/ijo.2016.3488.
    PubMed     Text format     Abstract available


  49. WANG Z, Du T, Dong X, Li Z, et al
    Autophagy inhibition facilitates erlotinib cytotoxicity in lung cancer cells through modulation of endoplasmic reticulum stress.
    Int J Oncol. 2016 Apr 1. doi: 10.3892/ijo.2016.3468.
    PubMed     Text format     Abstract available


  50. HONG WG, Cho JH, Hwang SG, Lee E, et al
    Chemosensitizing effect of podophyllotoxin acetate on topoisomerase inhibitors leads to synergistic enhancement of lung cancer cell apoptosis.
    Int J Oncol. 2016 Apr 1. doi: 10.3892/ijo.2016.3471.
    PubMed     Text format     Abstract available


  51. GAROUSI J, Andersson KG, Mitran B, Pichl ML, et al
    PET imaging of epidermal growth factor receptor expression in tumours using 89Zr-labelled ZEGFR:2377 affibody molecules.
    Int J Oncol. 2016;48:1325-32.
    PubMed     Text format     Abstract available


  52. ABU LILA AS, Kato C, Fukushima M, Huang CL, et al
    Downregulation of thymidylate synthase by RNAi molecules enhances the antitumor effect of pemetrexed in an orthotopic malignant mesothelioma xenograft mouse model.
    Int J Oncol. 2016;48:1399-407.
    PubMed     Text format     Abstract available


  53. MEENACH SA, Tsoras AN, McGarry RC, Mansour HM, et al
    Development of three-dimensional lung multicellular spheroids in air- and liquid-interface culture for the evaluation of anticancer therapeutics.
    Int J Oncol. 2016;48:1701-9.
    PubMed     Text format     Abstract available


    March 2016
  54. MA Y, Li M, Si J, Xiong Y, et al
    Blockade of Notch3 inhibits the stem-like property and is associated with ALDH1A1 and CD44 via autophagy in non-small lung cancer.
    Int J Oncol. 2016 Mar 30. doi: 10.3892/ijo.2016.3464.
    PubMed     Text format     Abstract available


  55. IZUMI H, Nagao S, Mochizuki S, Fujiwara N, et al
    Optimal sequence of antisense DNA to silence YB-1 in lung cancer by use of a novel polysaccharide drug delivery system.
    Int J Oncol. 2016 Mar 23. doi: 10.3892/ijo.2016.3451.
    PubMed     Text format     Abstract available


  56. ZURYN A, Litwiniec A, Safiejko-Mroczka B, Klimaszewska-Wisniewska A, et al
    The effect of sulforaphane on the cell cycle, apoptosis and expression of cyclin D1 and p21 in the A549 non-small cell lung cancer cell line.
    Int J Oncol. 2016 Mar 18. doi: 10.3892/ijo.2016.3444.
    PubMed     Text format     Abstract available


  57. JIA Y, Wang Z, Zang A, Jiao S, et al
    Tetramethylpyrazine inhibits tumor growth of lung cancer through disrupting angiogenesis via BMP/Smad/Id-1 signaling.
    Int J Oncol. 2016 Mar 15. doi: 10.3892/ijo.2016.3443.
    PubMed     Text format     Abstract available


  58. KIM EO, Kang SE, Im CR, Lee JH, et al
    Tanshinone IIA induces TRAIL sensitization of human lung cancer cells through selective ER stress induction.
    Int J Oncol. 2016 Mar 15. doi: 10.3892/ijo.2016.3441.
    PubMed     Text format     Abstract available


  59. IN JK, Kim JK, Oh JS, Seo DW, et al
    5-Caffeoylquinic acid inhibits invasion of non-small cell lung cancer cells through the inactivation of p70S6K and Akt activity: Involvement of p53 in differential regulation of signaling pathways.
    Int J Oncol. 2016 Mar 10. doi: 10.3892/ijo.2016.3436.
    PubMed     Text format     Abstract available


  60. NISHIMURA Y, Hyuga S, Takiguchi S, Hyuga M, et al
    Ephedrae herba stimulates hepatocyte growth factor-induced MET endocytosis and downregulation via early/late endocytic pathways in gefitinib-resistant human lung cancer cells.
    Int J Oncol. 2016 Mar 7. doi: 10.3892/ijo.2016.3426.
    PubMed     Text format     Abstract available


  61. CREGAN S, McDonagh L, Gao Y, Barr MP, et al
    KAT5 (Tip60) is a potential therapeutic target in malignant pleural mesothelioma.
    Int J Oncol. 2016;48:1290-6.
    PubMed     Text format     Abstract available


    February 2016
  62. OUYANG Q, Zhang L, Jiang Y, Ni X, et al
    The membrane complement regulatory protein CD59 promotes tumor growth and predicts poor prognosis in breast cancer.
    Int J Oncol. 2016 Feb 24. doi: 10.3892/ijo.2016.3408.
    PubMed     Text format     Abstract available


  63. WANG SQ, Zhao BX, Liu Y, Wang YT, et al
    New application of an old drug: Antitumor activity and mechanisms of doxycycline in small cell lung cancer.
    Int J Oncol. 2016 Feb 4. doi: 10.3892/ijo.2016.3375.
    PubMed     Text format     Abstract available


    January 2016
  64. NISHIJIMA N, Seike M, Soeno C, Chiba M, et al
    miR-200/ZEB axis regulates sensitivity to nintedanib in non-small cell lung cancer cells.
    Int J Oncol. 2016 Jan 11. doi: 10.3892/ijo.2016.3331.
    PubMed     Text format     Abstract available


    December 2015
  65. MA L, Wang R, Nan Y, Li W, et al
    Phloretin exhibits an anticancer effect and enhances the anticancer ability of cisplatin on non-small cell lung cancer cell lines by regulating expression of apoptotic pathways and matrix metalloproteinases.
    Int J Oncol. 2015 Dec 21. doi: 10.3892/ijo.2015.3304.
    PubMed     Text format     Abstract available


  66. QU J, Yu H, Li F, Zhang C, et al
    Molecular basis of antibody binding to mucin glycopeptides in lung cancer.
    Int J Oncol. 2015 Dec 18. doi: 10.3892/ijo.2015.3302.
    PubMed     Text format     Abstract available


  67. ZHAO Q, Mao A, Yan J, Sun C, et al
    Downregulation of Nrf2 promotes radiation-induced apoptosis through Nrf2 mediated Notch signaling in non-small cell lung cancer cells.
    Int J Oncol. 2015 Dec 18. doi: 10.3892/ijo.2015.3301.
    PubMed     Text format     Abstract available


  68. CHU K, Gao G, Yang X, Ren S, et al
    miR-512-5p induces apoptosis and inhibits glycolysis by targeting p21 in non-small cell lung cancer cells.
    Int J Oncol. 2015 Dec 7. doi: 10.3892/ijo.2015.3279.
    PubMed     Text format     Abstract available


    November 2015
  69. WANG S, Li X, Zhu R, Han Q, et al
    Lung cancer exosomes initiate global long non-coding RNA changes in mesenchymal stem cells.
    Int J Oncol. 2015 Nov 27. doi: 10.3892/ijo.2015.3272.
    PubMed     Text format     Abstract available


  70. KIM N, Song M, Kim S, Seo Y, et al
    Differential regulation and synthetic lethality of exclusive RB1 and CDKN2A mutations in lung cancer.
    Int J Oncol. 2015 Nov 20. doi: 10.3892/ijo.2015.3262.
    PubMed     Text format     Abstract available


  71. LEE YM, Lee G, Oh TI, Kim BM, et al
    Inhibition of glutamine utilization sensitizes lung cancer cells to apigenin-induced apoptosis resulting from metabolic and oxidative stress.
    Int J Oncol. 2015 Nov 11. doi: 10.3892/ijo.2015.3243.
    PubMed     Text format     Abstract available


    July 2015
  72. NAGANO K, Imai S, Zhao X, Yamashita T, et al
    Identification and evaluation of metastasis-related proteins, oxysterol binding protein-like 5 and calumenin, in lung tumors.
    Int J Oncol. 2015;47:195-203.
    PubMed     Text format     Abstract available


    February 2015
  73. MA J, Lu H, Wang S, Chen B, et al
    The anthraquinone derivative Emodin inhibits angiogenesis and metastasis through downregulating Runx2 activity in breast cancer.
    Int J Oncol. 2015 Feb 10. doi: 10.3892/ijo.2015.2888.
    PubMed     Text format     Abstract available


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