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  Lung Cancer

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Articles published in Int J Oncol

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Single Articles


    February 2017
  1. YANG X, Han M, Han H, Wang B, et al
    Silencing Snail suppresses tumor cell proliferation and invasion by reversing epithelial-to-mesenchymal transition and arresting G2/M phase in non-small cell lung cancer.
    Int J Oncol. 2017 Feb 21. doi: 10.3892/ijo.2017.3888.
    PubMed     Text format     Abstract available


  2. SRINUAL S, Chanvorachote P, Pongrakhananon V
    Suppression of cancer stem-like phenotypes in NCI-H460 lung cancer cells by vanillin through an Akt-dependent pathway.
    Int J Oncol. 2017 Feb 17. doi: 10.3892/ijo.2017.3879.
    PubMed     Text format     Abstract available


  3. XIONG Y, Wang M, Zhao J, Wang L, et al
    SIRT3 is correlated with the malignancy of non-small cell lung cancer.
    Int J Oncol. 2017 Feb 2. doi: 10.3892/ijo.2017.3868.
    PubMed     Text format     Abstract available


  4. SCHNEIDER MA, Christopoulos P, Muley T, Warth A, et al
    AURKA, DLGAP5, TPX2, KIF11 and CKAP5: Five specific mitosis-associated genes correlate with poor prognosis for non-small cell lung cancer patients.
    Int J Oncol. 2017;50:365-372.
    PubMed     Text format     Abstract available


    January 2017
  5. RUI Y, Peng WJ, Wang M, Wang Q, et al
    HIST1H3D: A promising therapeutic target for lung cancer.
    Int J Oncol. 2017 Jan 19. doi: 10.3892/ijo.2017.3856.
    PubMed     Text format     Abstract available


    December 2016
  6. CAO K, Pan Y, Yu L, Shu X, et al
    Monoclonal antibodies targeting non-small cell lung cancer stem-like cells by multipotent cancer stem cell monoclonal antibody library.
    Int J Oncol. 2016 Dec 22. doi: 10.3892/ijo.2016.3818.
    PubMed     Text format     Abstract available


  7. TU Z, Xie S, Xiong M, Liu Y, et al
    CXCR4 is involved in CD133-induced EMT in non-small cell lung cancer.
    Int J Oncol. 2016 Dec 19. doi: 10.3892/ijo.2016.3812.
    PubMed     Text format     Abstract available


  8. ABDELBASET-ISMAIL A, Pedziwiatr D, Schneider G, Niklinski J, et al
    Pituitary sex hormones enhance the prometastatic potential of human lung cancer cells by downregulating the intracellular expression of heme oxygenase1.
    Int J Oncol. 2016 Dec 2. doi: 10.3892/ijo.2016.3787.
    PubMed     Text format     Abstract available


    November 2016
  9. XU Z, Mei J, Tan Y
    Baicalin attenuates DDP (cisplatin) resistance in lung cancer by downregulating MARK2 and p-Akt.
    Int J Oncol. 2016 Nov 15. doi: 10.3892/ijo.2016.3768.
    PubMed     Text format     Abstract available


    October 2016
  10. CHIBA M, Togashi Y, Tomida S, Mizuuchi H, et al
    MEK inhibitors against MET-amplified non-small cell lung cancer.
    Int J Oncol. 2016 Oct 17. doi: 10.3892/ijo.2016.3736.
    PubMed     Text format     Abstract available


  11. WANG Z, Xu W, Lin Z, Li C, et al
    Reduced apurinic/apyrimidinic endonuclease activity enhances the antitumor activity of oxymatrine in lung cancer cells.
    Int J Oncol. 2016 Oct 14. doi: 10.3892/ijo.2016.3734.
    PubMed     Text format     Abstract available


  12. JEON YJ, Bang W, Cho JH, Lee RH, et al
    Kahweol induces apoptosis by suppressing BTF3 expression through the ERK signaling pathway in non-small cell lung cancer cells.
    Int J Oncol. 2016 Oct 12. doi: 10.3892/ijo.2016.3727.
    PubMed     Text format     Abstract available


  13. HE Y, Zhang X, Wang L, Tian Z, et al
    Detection of cancer specific mutations in early-stage non-small cell lung cancer using cell-free DNA by targeted sequencing.
    Int J Oncol. 2016 Oct 12. doi: 10.3892/ijo.2016.3731.
    PubMed     Text format     Abstract available


    September 2016
  14. CZARNECKA KH, Migdalska-Sek M, Domanska D, Pastuszak-Lewandoska D, et al
    FHIT promoter methylation status, low protein and high mRNA levels in patients with non-small cell lung cancer.
    Int J Oncol. 2016;49:1175-84.
    PubMed     Text format     Abstract available


  15. YAMADA H, Takeda T, Michiue H, Abe T, et al
    Actin bundling by dynamin 2 and cortactin is implicated in cell migration by stabilizing filopodia in human non-small cell lung carcinoma cells.
    Int J Oncol. 2016;49:877-86.
    PubMed     Text format     Abstract available


    August 2016
  16. XU SW, Law BY, Mok SW, Leung EL, et al
    Autophagic degradation of epidermal growth factor receptor in gefitinib-resistant lung cancer by celastrol.
    Int J Oncol. 2016 Aug 3. doi: 10.3892/ijo.2016.3644.
    PubMed     Text format     Abstract available


    July 2016
  17. HUANG T, She K, Peng G, Wang W, et al
    MicroRNA-186 suppresses cell proliferation and metastasis through targeting MAP3K2 in non-small cell lung cancer.
    Int J Oncol. 2016 Jul 29. doi: 10.3892/ijo.2016.3637.
    PubMed     Text format     Abstract available


  18. ZHANG N, Zeng Y, Du W, Zhu J, et al
    The EGFR pathway is involved in the regulation of PD-L1 expression via the IL-6/JAK/STAT3 signaling pathway in EGFR-mutated non-small cell lung cancer.
    Int J Oncol. 2016 Jul 26. doi: 10.3892/ijo.2016.3632.
    PubMed     Text format     Abstract available


  19. XIA H, Li Y, Lv X
    MicroRNA-107 inhibits tumor growth and metastasis by targeting the BDNF-mediated PI3K/AKT pathway in human non-small lung cancer.
    Int J Oncol. 2016 Jul 25. doi: 10.3892/ijo.2016.3628.
    PubMed     Text format     Abstract available


  20. PUCHSAKA P, Chaotham C, Chanvorachote P
    alpha-Lipoic acid sensitizes lung cancer cells to chemotherapeutic agents and anoikis via integrin beta1/beta3 downregulation.
    Int J Oncol. 2016 Jul 18. doi: 10.3892/ijo.2016.3624.
    PubMed     Text format     Abstract available


    June 2016
  21. YANG X, Tietje AH, Yu X, Wei Y, et al
    Mouse interleukin-12/FasTI: A novel bi-functional fusion protein for cancer immuno/gene therapy.
    Int J Oncol. 2016;48:2381-6.
    PubMed     Text format     Abstract available


    May 2016
  22. KURIMOTO R, Iwasawa S, Ebata T, Ishiwata T, et al
    Drug resistance originating from a TGF-beta/FGF-2-driven epithelial-to-mesenchymal transition and its reversion in human lung adenocarcinoma cell lines harboring an EGFR mutation.
    Int J Oncol. 2016;48:1825-36.
    PubMed     Text format     Abstract available


  23. HAN J, Zhao F, Zhang J, Zhu H, et al
    miR-223 reverses the resistance of EGFR-TKIs through IGF1R/PI3K/Akt signaling pathway.
    Int J Oncol. 2016;48:1855-67.
    PubMed     Text format     Abstract available


    April 2016
  24. MARCUS MW, Raji OY, Duffy SW, Young RP, et al
    Incorporating epistasis interaction of genetic susceptibility single nucleotide polymorphisms in a lung cancer risk prediction model.
    Int J Oncol. 2016 Apr 25. doi: 10.3892/ijo.2016.3499.
    PubMed     Text format     Abstract available


  25. XIAO X, He Z, Cao W, Cai F, et al
    Oridonin inhibits gefitinib-resistant lung cancer cells by suppressing EGFR/ERK/MMP-12 and CIP2A/Akt signaling pathways.
    Int J Oncol. 2016 Apr 15. doi: 10.3892/ijo.2016.3488.
    PubMed     Text format     Abstract available


  26. WANG Z, Du T, Dong X, Li Z, et al
    Autophagy inhibition facilitates erlotinib cytotoxicity in lung cancer cells through modulation of endoplasmic reticulum stress.
    Int J Oncol. 2016 Apr 1. doi: 10.3892/ijo.2016.3468.
    PubMed     Text format     Abstract available


  27. HONG WG, Cho JH, Hwang SG, Lee E, et al
    Chemosensitizing effect of podophyllotoxin acetate on topoisomerase inhibitors leads to synergistic enhancement of lung cancer cell apoptosis.
    Int J Oncol. 2016 Apr 1. doi: 10.3892/ijo.2016.3471.
    PubMed     Text format     Abstract available


  28. GAROUSI J, Andersson KG, Mitran B, Pichl ML, et al
    PET imaging of epidermal growth factor receptor expression in tumours using 89Zr-labelled ZEGFR:2377 affibody molecules.
    Int J Oncol. 2016;48:1325-32.
    PubMed     Text format     Abstract available


  29. ABU LILA AS, Kato C, Fukushima M, Huang CL, et al
    Downregulation of thymidylate synthase by RNAi molecules enhances the antitumor effect of pemetrexed in an orthotopic malignant mesothelioma xenograft mouse model.
    Int J Oncol. 2016;48:1399-407.
    PubMed     Text format     Abstract available


  30. MEENACH SA, Tsoras AN, McGarry RC, Mansour HM, et al
    Development of three-dimensional lung multicellular spheroids in air- and liquid-interface culture for the evaluation of anticancer therapeutics.
    Int J Oncol. 2016;48:1701-9.
    PubMed     Text format     Abstract available


    March 2016
  31. MA Y, Li M, Si J, Xiong Y, et al
    Blockade of Notch3 inhibits the stem-like property and is associated with ALDH1A1 and CD44 via autophagy in non-small lung cancer.
    Int J Oncol. 2016 Mar 30. doi: 10.3892/ijo.2016.3464.
    PubMed     Text format     Abstract available


  32. IZUMI H, Nagao S, Mochizuki S, Fujiwara N, et al
    Optimal sequence of antisense DNA to silence YB-1 in lung cancer by use of a novel polysaccharide drug delivery system.
    Int J Oncol. 2016 Mar 23. doi: 10.3892/ijo.2016.3451.
    PubMed     Text format     Abstract available


  33. ZURYN A, Litwiniec A, Safiejko-Mroczka B, Klimaszewska-Wisniewska A, et al
    The effect of sulforaphane on the cell cycle, apoptosis and expression of cyclin D1 and p21 in the A549 non-small cell lung cancer cell line.
    Int J Oncol. 2016 Mar 18. doi: 10.3892/ijo.2016.3444.
    PubMed     Text format     Abstract available


  34. JIA Y, Wang Z, Zang A, Jiao S, et al
    Tetramethylpyrazine inhibits tumor growth of lung cancer through disrupting angiogenesis via BMP/Smad/Id-1 signaling.
    Int J Oncol. 2016 Mar 15. doi: 10.3892/ijo.2016.3443.
    PubMed     Text format     Abstract available


  35. KIM EO, Kang SE, Im CR, Lee JH, et al
    Tanshinone IIA induces TRAIL sensitization of human lung cancer cells through selective ER stress induction.
    Int J Oncol. 2016 Mar 15. doi: 10.3892/ijo.2016.3441.
    PubMed     Text format     Abstract available


  36. IN JK, Kim JK, Oh JS, Seo DW, et al
    5-Caffeoylquinic acid inhibits invasion of non-small cell lung cancer cells through the inactivation of p70S6K and Akt activity: Involvement of p53 in differential regulation of signaling pathways.
    Int J Oncol. 2016 Mar 10. doi: 10.3892/ijo.2016.3436.
    PubMed     Text format     Abstract available


  37. NISHIMURA Y, Hyuga S, Takiguchi S, Hyuga M, et al
    Ephedrae herba stimulates hepatocyte growth factor-induced MET endocytosis and downregulation via early/late endocytic pathways in gefitinib-resistant human lung cancer cells.
    Int J Oncol. 2016 Mar 7. doi: 10.3892/ijo.2016.3426.
    PubMed     Text format     Abstract available


  38. CREGAN S, McDonagh L, Gao Y, Barr MP, et al
    KAT5 (Tip60) is a potential therapeutic target in malignant pleural mesothelioma.
    Int J Oncol. 2016;48:1290-6.
    PubMed     Text format     Abstract available


    February 2016
  39. OUYANG Q, Zhang L, Jiang Y, Ni X, et al
    The membrane complement regulatory protein CD59 promotes tumor growth and predicts poor prognosis in breast cancer.
    Int J Oncol. 2016 Feb 24. doi: 10.3892/ijo.2016.3408.
    PubMed     Text format     Abstract available


  40. WANG SQ, Zhao BX, Liu Y, Wang YT, et al
    New application of an old drug: Antitumor activity and mechanisms of doxycycline in small cell lung cancer.
    Int J Oncol. 2016 Feb 4. doi: 10.3892/ijo.2016.3375.
    PubMed     Text format     Abstract available


    January 2016
  41. NISHIJIMA N, Seike M, Soeno C, Chiba M, et al
    miR-200/ZEB axis regulates sensitivity to nintedanib in non-small cell lung cancer cells.
    Int J Oncol. 2016 Jan 11. doi: 10.3892/ijo.2016.3331.
    PubMed     Text format     Abstract available


    December 2015
  42. MA L, Wang R, Nan Y, Li W, et al
    Phloretin exhibits an anticancer effect and enhances the anticancer ability of cisplatin on non-small cell lung cancer cell lines by regulating expression of apoptotic pathways and matrix metalloproteinases.
    Int J Oncol. 2015 Dec 21. doi: 10.3892/ijo.2015.3304.
    PubMed     Text format     Abstract available


  43. QU J, Yu H, Li F, Zhang C, et al
    Molecular basis of antibody binding to mucin glycopeptides in lung cancer.
    Int J Oncol. 2015 Dec 18. doi: 10.3892/ijo.2015.3302.
    PubMed     Text format     Abstract available


  44. ZHAO Q, Mao A, Yan J, Sun C, et al
    Downregulation of Nrf2 promotes radiation-induced apoptosis through Nrf2 mediated Notch signaling in non-small cell lung cancer cells.
    Int J Oncol. 2015 Dec 18. doi: 10.3892/ijo.2015.3301.
    PubMed     Text format     Abstract available


  45. CHU K, Gao G, Yang X, Ren S, et al
    miR-512-5p induces apoptosis and inhibits glycolysis by targeting p21 in non-small cell lung cancer cells.
    Int J Oncol. 2015 Dec 7. doi: 10.3892/ijo.2015.3279.
    PubMed     Text format     Abstract available


    November 2015
  46. WANG S, Li X, Zhu R, Han Q, et al
    Lung cancer exosomes initiate global long non-coding RNA changes in mesenchymal stem cells.
    Int J Oncol. 2015 Nov 27. doi: 10.3892/ijo.2015.3272.
    PubMed     Text format     Abstract available


  47. KIM N, Song M, Kim S, Seo Y, et al
    Differential regulation and synthetic lethality of exclusive RB1 and CDKN2A mutations in lung cancer.
    Int J Oncol. 2015 Nov 20. doi: 10.3892/ijo.2015.3262.
    PubMed     Text format     Abstract available


  48. LEE YM, Lee G, Oh TI, Kim BM, et al
    Inhibition of glutamine utilization sensitizes lung cancer cells to apigenin-induced apoptosis resulting from metabolic and oxidative stress.
    Int J Oncol. 2015 Nov 11. doi: 10.3892/ijo.2015.3243.
    PubMed     Text format     Abstract available


    October 2015
  49. ZINNER R, Grul CV, Spigel DR, Obasaju C, et al
    Pemetrexed clinical studies in performance status 2 patients with non-small cell lung cancer (Review).
    Int J Oncol. 2015 Oct 29. doi: 10.3892/ijo.2015.3219.
    PubMed     Text format     Abstract available


  50. KIM KC, Baek SH, Lee C
    Curcumin-induced downregulation of Axl receptor tyrosine kinase inhibits cell proliferation and circumvents chemoresistance in non-small lung cancer cells.
    Int J Oncol. 2015 Oct 21. doi: 10.3892/ijo.2015.3216.
    PubMed     Text format     Abstract available


  51. MUTO S, Owada Y, Inoue T, Watanabe Y, et al
    Clinical significance of expanded Foxp3+ Helios- regulatory T cells in patients with non-small cell lung cancer.
    Int J Oncol. 2015 Oct 12. doi: 10.3892/ijo.2015.3196.
    PubMed     Text format     Abstract available


    September 2015
  52. FUNAMIZU N, Lacy CR, Kamada M, Yanaga K, et al
    MicroRNA-203 induces apoptosis by upregulating Puma expression in colon and lung cancer cells.
    Int J Oncol. 2015 Sep 22. doi: 10.3892/ijo.2015.3178.
    PubMed     Text format     Abstract available


  53. JIN G, Jin M, Yin X, Jin Z, et al
    A comparative study on the effect of docetaxel-albumin nanoparticles and docetaxel-loaded PEG-albumin nanoparticles against non-small cell lung cancer.
    Int J Oncol. 2015 Sep 18. doi: 10.3892/ijo.2015.3174.
    PubMed     Text format     Abstract available


    August 2015
  54. BITTONI MA, Focht BC, Clinton SK, Buckworth J, et al
    Prospective evaluation of C-reactive protein, smoking and lung cancer death in the Third National Health and Nutrition Examination Survey.
    Int J Oncol. 2015 Aug 31. doi: 10.3892/ijo.2015.3141.
    PubMed     Text format     Abstract available


  55. MA L, Li W, Wang R, Nan Y, et al
    Resveratrol enhanced anticancer effects of cisplatin on non-small cell lung cancer cell lines by inducing mitochondrial dysfunction and cell apoptosis.
    Int J Oncol. 2015 Aug 13. doi: 10.3892/ijo.2015.3124.
    PubMed     Text format     Abstract available


  56. CHOI JY, Hong WG, Cho JH, Kim EM, et al
    Podophyllotoxin acetate triggers anticancer effects against non-small cell lung cancer cells by promoting cell death via cell cycle arrest, ER stress and autophagy.
    Int J Oncol. 2015 Aug 13. doi: 10.3892/ijo.2015.3123.
    PubMed     Text format     Abstract available


  57. PARK DH, Jeon HS, Lee SY, Choi YY, et al
    MicroRNA-146a inhibits epithelial mesenchymal transition in non-small cell lung cancer by targeting insulin receptor substrate 2.
    Int J Oncol. 2015 Aug 4. doi: 10.3892/ijo.2015.3111.
    PubMed     Text format     Abstract available


    July 2015
  58. ROSIERE R, Gelbcke M, Mathieu V, Van Antwerpen P, et al
    New dry powders for inhalation containing temozolomide-based nanomicelles for improved lung cancer therapy.
    Int J Oncol. 2015 Jul 20. doi: 10.3892/ijo.2015.3092.
    PubMed     Text format     Abstract available


  59. DEVERY AM, Wadekar R, Bokobza SM, Weber AM, et al
    Vascular endothelial growth factor directly stimulates tumour cell proliferation in non-small cell lung cancer.
    Int J Oncol. 2015 Jul 14. doi: 10.3892/ijo.2015.3082.
    PubMed     Text format     Abstract available


  60. NAGANO K, Imai S, Zhao X, Yamashita T, et al
    Identification and evaluation of metastasis-related proteins, oxysterol binding protein-like 5 and calumenin, in lung tumors.
    Int J Oncol. 2015;47:195-203.
    PubMed     Text format     Abstract available


    June 2015
  61. SAHA S, Bhattacharjee P, Guha D, Kajal K, et al
    Sulphur alters NFkappaB-p300 cross-talk in favour of p53-p300 to induce apoptosis in non-small cell lung carcinoma.
    Int J Oncol. 2015 Jun 22. doi: 10.3892/ijo.2015.3061.
    PubMed     Text format     Abstract available


  62. LIN X, Li HR, Lin XF, Yu ME, et al
    Silencing of Livin inhibits tumorigenesis and metastasis via VEGF and MMPs pathway in lung cancer.
    Int J Oncol. 2015 Jun 19. doi: 10.3892/ijo.2015.3058.
    PubMed     Text format     Abstract available


  63. OLAJIDE OO, Field JK, Davies MM, Marcus MW, et al
    Lung cancer trend in England for the period of 2002 to 2011 and projections of future burden until 2020.
    Int J Oncol. 2015 Jun 15. doi: 10.3892/ijo.2015.3049.
    PubMed     Text format     Abstract available


  64. SUZUKI M, Mohamed S, Nakajima T, Kubo R, et al
    [Corrigendum] Aberrant methylation of CXCL12 in non-small cell lung cancer is associated with an unfavorable prognosis.
    Int J Oncol. 2015 Jun 12. doi: 10.3892/ijo.2015.3046.
    PubMed     Text format     Abstract available


  65. LEI J, Li QH, Yang JL, Liu F, et al
    The antitumor effects of oncolytic adenovirus H101 against lung cancer.
    Int J Oncol. 2015 Jun 11. doi: 10.3892/ijo.2015.3045.
    PubMed     Text format     Abstract available


    March 2015
  66. OKABE N, Ezaki J, Yamaura T, Muto S, et al
    FAM83B is a novel biomarker for diagnosis and prognosis of lung squamous cell carcinoma.
    Int J Oncol. 2015;46:999-1006.
    PubMed     Text format     Abstract available


  67. IZUMI H, Touge H, Igishi T, Makino H, et al
    Favorable effect of the combination of vinorelbine and dihydropyrimidine dehydrogenaseinhibitory fluoropyrimidine in EGFRmutated lung adenocarcinoma: retrospective and in vitro studies.
    Int J Oncol. 2015;46:989-98.
    PubMed     Text format     Abstract available


  68. MENG G, Wang W, Chai K, Yang S, et al
    Combination treatment with triptolide and hydroxycamptothecin synergistically enhances apoptosis in A549 lung adenocarcinoma cells through PP2A-regulated ERK, p38 MAPKs and Akt signaling pathways.
    Int J Oncol. 2015;46:1007-17.
    PubMed     Text format     Abstract available


  69. MATAKI H, Seki N, Chiyomaru T, Enokida H, et al
    Tumor-suppressive microRNA-206 as a dual inhibitor of MET and EGFR oncogenic signaling in lung squamous cell carcinoma.
    Int J Oncol. 2015;46:1039-50.
    PubMed     Text format     Abstract available


  70. KIM KH, Yoon G, Cho JJ, Cho JH, et al
    Licochalcone A induces apoptosis in malignant pleural mesothelioma through downregulation of Sp1 and subsequent activation of mitochondria-related apoptotic pathway.
    Int J Oncol. 2015;46:1385-92.
    PubMed     Text format     Abstract available


  71. JUNG J, Jeong SY, Park SS, Shin SH, et al
    A cisplatinincorporated liposome that targets the epidermal growth factor receptor enhances radiotherapeutic efficacy without nephrotoxicity.
    Int J Oncol. 2015;46:1268-74.
    PubMed     Text format     Abstract available


    February 2015
  72. MA J, Lu H, Wang S, Chen B, et al
    The anthraquinone derivative Emodin inhibits angiogenesis and metastasis through downregulating Runx2 activity in breast cancer.
    Int J Oncol. 2015 Feb 10. doi: 10.3892/ijo.2015.2888.
    PubMed     Text format     Abstract available


  73. LI X, Yu Z, Li Y, Liu S, et al
    The tumor suppressor miR-124 inhibits cell proliferation by targeting STAT3 and functions as a prognostic marker for postoperative NSCLC patients.
    Int J Oncol. 2015;46:798-808.
    PubMed     Text format     Abstract available


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