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Amedeo Prize 2008
The 21 Finalists


  Lung Cancer

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Articles published in Oncogene

Retrieve available abstracts of 70 articles:
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Single Articles


    April 2008
  1. FREDERICK LA , Matthews JA, Jamieson L, Justilien V, et al
    Matrix metalloproteinase-10 is a critical effector of protein kinase Ciota-Par6alpha-mediated lung cancer.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


  2. LI D , Ambrogio L, Shimamura T, Kubo S, et al
    BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


  3. OGIWARA H , Kohno T, Nakanishi H, Nagayama K, et al
    Unbalanced translocation, a major chromosome alteration causing loss of heterozygosity in human lung cancer.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


    March 2008
  4. CHEN Z , Feng J, Saldivar JS, Gu D, et al
    EGFR somatic doublets in lung cancer are frequent and generally arise from a pair of driver mutations uncommonly seen as singlet mutations: one-third of doublets occur at five pairs of amino acids.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


    February 2008
  5. WENDT MK , Cooper AN, Dwinell MB
    Epigenetic silencing of CXCL12 increases the metastatic potential of mammary carcinoma cells.
    Oncogene. 2008;27:1461-71.
    PubMed     Related articles    Abstract available


  6. SAFINA A , Ren MQ, Vandette E, Bakin AV, et al
    TAK1 is required for TGF-beta 1-mediated regulation of matrix metalloproteinase-9 and metastasis.
    Oncogene. 2008;27:1198-207.
    PubMed     Related articles    Abstract available


  7. GAROFALO M , Quintavalle C, Di Leva G, Zanca C, et al
    MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


    January 2008
  8. FALVELLA FS , Colombo F, Spinola M, Campiglio M, et al
    BHLHB3: a candidate tumor suppressor in lung cancer.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


  9. KWEI KA , Kim YH, Girard L, Kao J, et al
    Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


  10. BORCZUK AC , Papanikolaou N, Toonkel RL, Sole M, et al
    Lung adenocarcinoma invasion in TGFbetaRII-deficient cells is mediated by CCL5/RANTES.
    Oncogene. 2008;27:557-64.
    PubMed     Related articles    Abstract available


  11. RICHARD S , Vogel G, Huot ME, Guo T, et al
    Sam68 haploinsufficiency delays onset of mammary tumorigenesis and metastasis.
    Oncogene. 2008;27:548-56.
    PubMed     Related articles    Abstract available


  12. CHEN Z , Li J, Li QS, Fan JQ, et al
    Suppression of PPN/MG61 attenuates Wnt/beta-catenin signaling pathway and induces apoptosis in human lung cancer.
    Oncogene. 2008;.
    PubMed     Related articles    Abstract available


  13. MORIMOTO K , Satoh-Yamaguchi K, Hamaguchi A, Inoue Y, et al
    Interaction of cancer cells with platelets mediated by Necl-5/poliovirus receptor enhances cancer cell metastasis to the lungs.
    Oncogene. 2008;27:264-73.
    PubMed     Related articles    Abstract available


    December 2007
  14. SANCHEZ-CESPEDES M
    A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome.
    Oncogene. 2007;26:7825-32.
    PubMed     Related articles    Abstract available


  15. HAJJI N , Wallenborg K, Vlachos P, Nyman U, et al
    Combinatorial action of the HDAC inhibitor trichostatin A and etoposide induces caspase-mediated AIF-dependent apoptotic cell death in non-small cell lung carcinoma cells.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  16. CHETTY C , Bhoopathi P, Lakka SS, Rao JS, et al
    MMP-2 siRNA induced Fas/CD95-mediated extrinsic II apoptotic pathway in the A549 lung adenocarcinoma cell line.
    Oncogene. 2007;26:7675-83.
    PubMed     Related articles    Abstract available


    November 2007
  17. BRUTON RK , Rasti M, Mapp KL, Young N, et al
    C-terminal-binding protein interacting protein binds directly to adenovirus early region 1A through its N-terminal region and conserved region 3.
    Oncogene. 2007;26:7467-79.
    PubMed     Related articles    Abstract available


  18. YANG HY , Wen YY, Lin YI, Pham L, et al
    Roles for negative cell regulator 14-3-3sigma in control of MDM2 activities.
    Oncogene. 2007;26:7355-62.
    PubMed     Related articles    Abstract available


  19. SETHI G , Ahn KS, Chaturvedi MM, Aggarwal BB, et al
    Epidermal growth factor (EGF) activates nuclear factor-kappaB through IkappaBalpha kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IkappaBalpha.
    Oncogene. 2007;26:7324-32.
    PubMed     Related articles    Abstract available


    October 2007
  20. GLAROS S , Cirrincione GM, Muchardt C, Kleer CG, et al
    The reversible epigenetic silencing of BRM: implications for clinical targeted therapy.
    Oncogene. 2007;26:7058-66.
    PubMed     Related articles    Abstract available


  21. FLINTERMAN MB , Mymryk JS, Klanrit P, Yousef AF, et al
    p400 function is required for the adenovirus E1A-mediated suppression of EGFR and tumour cell killing.
    Oncogene. 2007;26:6863-74.
    PubMed     Related articles    Abstract available


  22. SALON C , Merdzhanova G, Brambilla C, Brambilla E, et al
    E2F-1, Skp2 and cyclin E oncoproteins are upregulated and directly correlated in high-grade neuroendocrine lung tumors.
    Oncogene. 2007;26:6927-36.
    PubMed     Related articles    Abstract available


  23. ROELLE S , Grosse R, Buech T, Chubanov V, et al
    Essential role of Pyk2 and Src kinase activation in neuropeptide-induced proliferation of small cell lung cancer cells.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  24. GALLEGO MA , Ballot C, Kluza J, Hajji N, et al
    Overcoming chemoresistance of non-small cell lung carcinoma through restoration of an AIF-dependent apoptotic pathway.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


    September 2007
  25. COOPER WN , Dickinson RE, Dallol A, Grigorieva EV, et al
    Epigenetic regulation of the ras effector/tumour suppressor RASSF2 in breast and lung cancer.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  26. XIAO W , Zhang Q, Habermacher G, Yang X, et al
    U19/Eaf2 knockout causes lung adenocarcinoma, B-cell lymphoma, hepatocellular carcinoma and prostatic intraepithelial neoplasia.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  27. MATSUBARA H , Takeuchi T, Nishikawa E, Yanagisawa K, et al
    Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92.
    Oncogene. 2007;26:6099-105.
    PubMed     Related articles    Abstract available


  28. YANG L , Lin C, Sun SY, Zhao S, et al
    A double tyrosine phosphorylation of P68 RNA helicase confers resistance to TRAIL-induced apoptosis.
    Oncogene. 2007;26:6082-92.
    PubMed     Related articles    Abstract available


    August 2007
  29. MATSUMOTO S , Iwakawa R, Takahashi K, Kohno T, et al
    Prevalence and specificity of LKB1 genetic alterations in lung cancers.
    Oncogene. 2007;26:5911-8.
    PubMed     Related articles    Abstract available


  30. FALVELLA FS , Spinola M, Pignatiello C, Noci S, et al
    AZGP1 mRNA levels in normal human lung tissue correlate with lung cancer disease status.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  31. RAMER R , Eichele K, Hinz B
    Upregulation of tissue inhibitor of matrix metalloproteinases-1 confers the anti-invasive action of cisplatin on human cancer cells.
    Oncogene. 2007;26:5822-7.
    PubMed     Related articles    Abstract available


  32. KUSTERS B , Kats G, Roodink I, Verrijp K, et al
    Micronodular transformation as a novel mechanism of VEGF-A-induced metastasis.
    Oncogene. 2007;26:5808-15.
    PubMed     Related articles    Abstract available


    July 2007
  33. KE Y , Wu D, Princen F, Nguyen T, et al
    Role of Gab2 in mammary tumorigenesis and metastasis.
    Oncogene. 2007;26:4951-60.
    PubMed     Related articles    Abstract available


  34. FU YN , Yeh CL, Cheng HH, Yang CH, et al
    EGFR mutants found in non-small cell lung cancer show different levels of sensitivity to suppression of Src: implications in targeting therapy.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  35. WU YH , Tsai Chang JH, Cheng YW, Wu TC, et al
    Xeroderma pigmentosum group C gene expression is predominantly regulated by promoter hypermethylation and contributes to p53 mutation in lung cancers.
    Oncogene. 2007;26:4761-73.
    PubMed     Related articles    Abstract available


  36. PREET A , Ganju RK, Groopman JE
    Delta(9)-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  37. ANGELONI D , Danilkovitch-Miagkova A, Ivanova T, Braga E, et al
    Hypermethylation of Ron proximal promoter associates with lack of full-length Ron and transcription of oncogenic short-Ron from an internal promoter.
    Oncogene. 2007;26:4499-512.
    PubMed     Related articles    Abstract available


  38. TOMIDA S , Yanagisawa K, Koshikawa K, Yatabe Y, et al
    Identification of a metastasis signature and the DLX4 homeobox protein as a regulator of metastasis by combined transcriptome approach.
    Oncogene. 2007;26:4600-8.
    PubMed     Related articles    Abstract available


    June 2007
  39. HAASE D , Meister M, Muley T, Hess J, et al
    FRMD3, a novel putative tumour suppressor in NSCLC.
    Oncogene. 2007;26:4464-8.
    PubMed     Related articles    Abstract available


  40. DESNOYERS LR , Pai R, Ferrando RE, Hotzel K, et al
    Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  41. TAI KY , Shiah SG, Shieh YS, Kao YR, et al
    DNA methylation and histone modification regulate silencing of epithelial cell adhesion molecule for tumor invasion and progression.
    Oncogene. 2007;26:3989-97.
    PubMed     Related articles    Abstract available


  42. LIN X , Morgan-Lappe S, Huang X, Li L, et al
    'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737.
    Oncogene. 2007;26:3972-9.
    PubMed     Related articles    Abstract available


  43. BARTKOVA J , Horej Sbreve I Z, Sehested M, Nesland JM, et al
    DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


    May 2007
  44. STINCHCOMBE TE , Socinski MA
    Bevacizumab in the treatment of non-small-cell lung cancer.
    Oncogene. 2007;26:3691-8.
    PubMed     Related articles    Abstract available


  45. SOMMER P , Le Rouzic P, Gillingham H, Berry A, et al
    Glucocorticoid receptor overexpression exerts an antisurvival effect on human small cell lung cancer cells.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  46. SHEPARD CR , Kassis J, Whaley DL, Kim HG, et al
    PLC gamma contributes to metastasis of in situ-occurring mammary and prostate tumors.
    Oncogene. 2007;26:3020-6.
    PubMed     Related articles    Abstract available


  47. ZHENG S , El-Naggar AK, Kim ES, Kurie JM, et al
    A genetic mouse model for metastatic lung cancer with gender differences in survival.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  48. LIN J , Sun T, Ji L, Deng W, et al
    Oncogenic activation of c-Abl in non-small cell lung cancer cells lacking FUS1 expression: inhibition of c-Abl by the tumor suppressor gene product Fus1.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  49. SHTIEGMAN K , Kochupurakkal BS, Zwang Y, Pines G, et al
    Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


    April 2007
  50. SANO A , Kage H, Sugimoto K, Kitagawa H, et al
    A second-generation profiling system for quantitative methylation analysis of multiple gene promoters: application to lung cancer.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


    March 2007
  51. LIU H , Zhou Y, Boggs SE, Belinsky SA, et al
    Cigarette smoke induces demethylation of prometastatic oncogene synuclein-gamma in lung cancer cells by downregulation of DNMT3B.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  52. IRMER D , Funk JO, Blaukat A
    EGFR kinase domain mutations - functional impact and relevance for lung cancer therapy.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


    February 2007
  53. MINAMI Y , Shimamura T, Shah K, Laframboise T, et al
    The major lung cancer-derived mutants of ERBB2 are oncogenic and are associated with sensitivity to the irreversible EGFR/ERBB2 inhibitor HKI-272.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  54. WIKMAN H , Ruosaari S, Nymark P, Sarhadi VK, et al
    Gene expression and copy number profiling suggests the importance of allelic imbalance in 19p in asbestos-associated lung cancer.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  55. WU Y , McRoberts K, Berr SS, Frierson HF Jr, et al
    Neuromedin U is regulated by the metastasis suppressor RhoGDI2 and is a novel promoter of tumor formation, lung metastasis and cancer cachexia.
    Oncogene. 2007;26:765-73.
    PubMed     Related articles    Abstract available


  56. WU X , Shell SM, Liu Y, Zou Y, et al
    ATR-dependent checkpoint modulates XPA nuclear import in response to UV irradiation.
    Oncogene. 2007;26:757-64.
    PubMed     Related articles    Abstract available


    January 2007
  57. KANG Y , Hong JA, Chen GA, Nguyen DM, et al
    Dynamic transcriptional regulatory complexes including BORIS, CTCF and Sp1 modulate NY-ESO-1 expression in lung cancer cells.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  58. CUI X , Zhang L, Luo J, Rajasekaran A, et al
    Unphosphorylated STAT6 contributes to constitutive cyclooxygenase-2 expression in human non-small cell lung cancer.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


  59. ZHANG YW , Staal B, Su Y, Swiatek P, et al
    Evidence that MIG-6 is a tumor-suppressor gene.
    Oncogene. 2007;26:269-76.
    PubMed     Related articles    Abstract available


  60. NAGAI H , Sugito N, Matsubara H, Tatematsu Y, et al
    CLCP1 interacts with semaphorin 4B and regulates motility of lung cancer cells.
    Oncogene. 2007;.
    PubMed     Related articles    Abstract available


    November 2006
  61. KO K , Furukawa K, Takahashi T, Urano T, et al
    Fundamental study of small interfering RNAs for ganglioside GD3 synthase gene as a therapeutic target of lung cancers.
    Oncogene. 2006;25:6924-35.
    PubMed     Related articles    Abstract available


    October 2006
  62. KHATLANI TS , Wislez M, Sun M, Srinivas H, et al
    c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells.
    Oncogene. 2006;.
    PubMed     Related articles    Abstract available


  63. ZHONG S , Fields CR, Su N, Pan YX, et al
    Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer.
    Oncogene. 2006;.
    PubMed     Related articles    Abstract available


    September 2006
  64. TOMKOVA K , El-Rifai W, Vilgelm A, Kelly MC, et al
    The gastrin gene promoter is regulated by p73 isoforms in tumor cells.
    Oncogene. 2006;25:6032-6.
    PubMed     Related articles    Abstract available


  65. CARRAGHER NO , Walker SM, Scott Carragher LA, Harris F, et al
    Calpain 2 and Src dependence distinguishes mesenchymal and amoeboid modes of tumour cell invasion: a link to integrin function.
    Oncogene. 2006;25:5726-40.
    PubMed     Related articles    Abstract available


  66. JACKSON-FISHER AJ , Bellinger G, Shum E, Duong JK, et al
    Formation of Neu/ErbB2-induced mammary tumors is unaffected by loss of ErbB4.
    Oncogene. 2006;25:5664-72.
    PubMed     Related articles    Abstract available


    August 2006
  67. SCAMBIA G , Lovergine S, Masciullo V
    RB family members as predictive and prognostic factors in human cancer.
    Oncogene. 2006;25:5302-8.
    PubMed     Related articles    Abstract available


  68. CUEVAS BD , Winter-Vann AM, Johnson NL, Johnson GL, et al
    MEKK1 controls matrix degradation and tumor cell dissemination during metastasis of polyoma middle-T driven mammary cancer.
    Oncogene. 2006;25:4998-5010.
    PubMed     Related articles    Abstract available


    July 2006
  69. MITRA SK , Lim ST, Chi A, Schlaepfer DD, et al
    Intrinsic focal adhesion kinase activity controls orthotopic breast carcinoma metastasis via the regulation of urokinase plasminogen activator expression in a syngeneic tumor model.
    Oncogene. 2006;25:4429-40.
    PubMed     Related articles    Abstract available


    May 2006
  70. CRUZ-MUNOZ W , Sanchez OH, Di Grappa M, English JL, et al
    Enhanced metastatic dissemination to multiple organs by melanoma and lymphoma cells in timp-3(-/-) mice.
    Oncogene. 2006;.
    PubMed     Related articles    Abstract available


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