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Articles published in Synapse

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    December 2014
  1. LIN SF, Labaree D, Chen MK, Holden D, et al
    Further evaluation of [ C]MP-10 as a radiotracer for phosphodiesterase 10A (PDE10A): PET imaging study in rhesus monkeys and brain tissue metabolite analysis.
    Synapse. 2014 Dec 2. doi: 10.1002/syn.21792.
    PubMed     Text format     Related articles    Abstract available


    September 2014
  2. CUMMING P, Skaper D, Kuwert T, Maschauer S, et al
    Detection of monoamine oxidase a in brain of living rats with [ F]fluoroethyl-harmol PET.
    Synapse. 2014 Sep 17. doi: 10.1002/syn.21785.
    PubMed     Text format     Related articles    Abstract available


  3. JOSHI AD, Sanabria-Bohorquez SM, Bormans G, Koole M, et al
    Characterization of the novel GlyT1 PET tracer [ F]MK-6577 in humans.
    Synapse. 2014 Sep 5. doi: 10.1002/syn.21782.
    PubMed     Text format     Related articles    Abstract available


  4. QUELCH D, De Santis V, Strege A, Myers J, et al
    Influence of agonist induced internalisation on [ H]Ro15-4513 binding - An application to imaging fluctuations in endogenous GABA with Positron Emission Tomography.
    Synapse. 2014 Sep 5. doi: 10.1002/syn.21780.
    PubMed     Text format     Related articles   


    August 2014
  5. MATHEWS WB, Kuwabara H, Stansfield K, Valentine H, et al
    Dose-dependent, saturable occupancy of the metabotropic glutamate subtype 5 receptor by fenobam as measured with [ C]ABP688 PET imaging.
    Synapse. 2014 Aug 6. doi: 10.1002/syn.21775.
    PubMed     Text format     Related articles    Abstract available


  6. LOHITH TG, Xu R, Tsujikawa T, Morse CL, et al
    Evaluation in monkey of two candidate PET radioligands, [ C]RX-1 and [ F]RX-2, for imaging brain 5HT receptors.
    Synapse. 2014 Aug 4. doi: 10.1002/syn.21773.
    PubMed     Text format     Related articles    Abstract available


    July 2014
  7. GALLEZOT JD, Bois F, Zheng MQ, Lin SF, et al
    Evaluation of the sensitivity of the novel alpha4beta2* nicotinic acetylcholine receptor PET radioligand F-(-)-NCFHEB to increases in synaptic acetylcholine levels in rhesus monkeys.
    Synapse. 2014 Jul 17. doi: 10.1002/syn.21767.
    PubMed     Text format     Related articles    Abstract available


  8. SHAPIRO PA, Sloan RP, Deochand C, Franceschi AM, et al
    Quantifying serotonin transporters by PET with [ C]-DASB before and after interferon-alphatreatment.
    Synapse. 2014 Jul 17. doi: 10.1002/syn.21766.
    PubMed     Text format     Related articles    Abstract available


  9. SURIDJAN I, Rusjan PM, Kenk M, Verhoeff NP, et al
    Quantitative imaging of neuroinflammation in human white matter: a Positron Emission Tomography (PET) study with Translocator protein 18kDA (TSPO) radioligand, [ F]-FEPPA.
    Synapse. 2014 Jul 17. doi: 10.1002/syn.21765.
    PubMed     Text format     Related articles    Abstract available


  10. TIGER M, Svenningsson P, Nord M, Jabre S, et al
    No correlation between serotonin and its metabolite 5-HIAA in the cerebrospinal fluid and [ C]AZ10419369 binding measured with PET in healthy volunteers.
    Synapse. 2014 Jul 2. doi: 10.1002/syn.21761.
    PubMed     Text format     Related articles    Abstract available


  11. KESSLER RM, Zald DH, Ansari MS, Li R, et al
    Changes in dopamine release and dopamine D2/3 receptor levels with the development of mild obesity.
    Synapse. 2014;68:317-20.
    PubMed     Text format     Related articles   


    June 2014
  12. AZIM MA, Kozaka T, Uno I, Miwa D, et al
    The potential of the vesicular acetylcholine transporter (VAChT) imaging using radiolabeled o-bromo-trans-decalinvesamicol (OBDV) as a new pet ligand.
    Synapse. 2014 Jun 21. doi: 10.1002/syn.21756.
    PubMed     Text format     Related articles    Abstract available


  13. ALBRECHT DS, Kareken DA, Christian BT, Dzemidzic M, et al
    Cortical dopamine release during a behavioral response inhibition task.
    Synapse. 2014;68:266-74.
    PubMed     Text format     Related articles    Abstract available


    March 2014
  14. NISHIYAMA S, Ohba H, Kobashi T, Nakamasu Y, et al
    Development of Novel PET Probe [ C](R,R)HAPT and its Stereoisomer [ C](S,S)HAPT for Vesicular Acetylcholine Transporter Imaging: A PET Study in Conscious Monkey.
    Synapse. 2014 Mar 29. doi: 10.1002/syn.21743.
    PubMed     Text format     Related articles    Abstract available


  15. KOZAKA T, Uno I, Kitamura Y, Miwa D, et al
    Regional brain imaging of vesicular acetylcholine transporter using o-[125 I]iodo-trans-decalinvesamicol as a new potential imaging probe.
    Synapse. 2014;68:107-13.
    PubMed     Text format     Related articles    Abstract available


    November 2013
  16. TAKANO A, Gulyas B, Varnas K, Little PB, et al
    Low brain CB1 receptor occupancy by a second generation CB1 receptor antagonist TM38837 in comparison with rimonabant in nonhuman primates: A PET study.
    Synapse. 2013 Nov 8. doi: 10.1002/syn.21721.
    PubMed     Text format     Related articles    Abstract available


    August 2013
  17. NAGANO-SAITO A , Dagher A, Booij L, Gravel P, et al
    Stress-induced dopamine release in human medial prefrontal cortex - F-Fallypride / PET study in healthy volunteers -
    Synapse. 2013 Aug 12. doi: 10.1002/syn.21700.
    PubMed     Text format     Related articles    Abstract available


  18. HILLMER AT , Wooten DW, Farhoud M, Higgins AT, et al
    PET imaging of acetylcholinesterase inhibitor induced effects on alpha4beta2 nicotinic acetylcholine receptor binding.
    Synapse. 2013 Aug 1. doi: 10.1002/syn.21698.
    PubMed     Text format     Related articles    Abstract available


  19. SANDIEGO CM , Nabulsi N, Lin SF, Labaree D, et al
    Studies of the metabotropic glutamate receptor 5 radioligand [(1)(1)C]ABP688 with N-acetylcysteine challenge in rhesus monkeys.
    Synapse. 2013;67:489-501.
    PubMed     Text format     Related articles    Abstract available


    May 2013
  20. LAN MJ , Hesselgrave N, Ciarleglio A, Ogden RT, et al
    Higher pre-treatment 5-HT receptor binding potential in bipolar disorder depression is associated with treatment remission: A naturalistic treatment pilot PET study.
    Synapse. 2013 May 30. doi: 10.1002/syn.21684.
    PubMed     Text format     Related articles    Abstract available


  21. KALK N , Owen D, Tyacke R, Reynolds R, et al
    Are prescribed benzodiazepines likely to affect the availability of the 18kDa translocator protein (TSPO) in PET studies?
    Synapse. 2013 May 12. doi: 10.1002/syn.21681.
    PubMed     Text format     Related articles   


  22. EISENSTEIN SA , Antenor-Dorsey JA, Gredysa DM, Koller JM, et al
    A comparison of D2 receptor specific binding in obese and normal-weight individuals using PET with (N-[ C]methyl)benperidol.
    Synapse. 2013 May 6. doi: 10.1002/syn.21680.
    PubMed     Text format     Related articles    Abstract available


    April 2013
  23. CUMMING P , Xiong G, la Fougere C, Rominger A, et al
    Surrogate markers for cerebral blood flow correlate with [(1)(8)F]-fallypride binding potential at dopamine D(2/3) receptors in human striatum.
    Synapse. 2013;67:199-203.
    PubMed     Text format     Related articles    Abstract available


    March 2013
  24. SAIGAL N , Bajwa AK, Faheem SS, Coleman RA, et al
    Evaluation of serotonin 5-HT receptors in rodent models using [ F]mefway PET.
    Synapse. 2013 Mar 18. doi: 10.1002/syn.21665.
    PubMed     Text format     Related articles    Abstract available


  25. FINNEMA SJ , Bang-Andersen B, Jorgensen M, Christoffersen CT, et al
    The dopamine D receptor agonist (S)-[ C]N-methyl-NNC 01-0259 is not sensitive to changes in dopamine concentration - a PET examination in the monkey brain.
    Synapse. 2013 Mar 18. doi: 10.1002/syn.21664.
    PubMed     Text format     Related articles    Abstract available


    February 2013
  26. HANSEN HD , Ettrup A, Herth MM, Dyssegaard A, et al
    Direct comparison of [(18) F]MH.MZ and [(18) F]altanserin for 5-HT(2A) receptor imaging with PET.
    Synapse. 2013 Feb 7. doi: 10.1002/syn.21643.
    PubMed     Text format     Related articles    Abstract available


    December 2012
  27. TOTH M , Varrone A, Steiger C, Laszlovszky I, et al
    Brain uptake and distribution of the dopamine D(3) /D(2) receptor partial agonist [(11) C]Cariprazine: An In Vivo positron emission tomography study in non-human primates.
    Synapse. 2012 Dec 14. doi: 10.1002/syn.21631.
    PubMed     Text format     Related articles    Abstract available


  28. CHOI JY , Kim CH, Jeon TJ, Kim BS, et al
    Effective microPET imaging of brain 5-HT(1A) receptors in rats with [(18) F]MeFWAY by suppression of radioligand defluorination.
    Synapse. 2012;66:1015-23.
    PubMed     Text format     Related articles    Abstract available


    November 2012
  29. MUNRO CA , Workman CI, Kramer E, Hermann C, et al
    Serotonin modulation of cerebral glucose metabolism: sex and age effects.
    Synapse. 2012;66:955-64.
    PubMed     Text format     Related articles    Abstract available


  30. TAVARES AA , Jobson NK, Dewar D, Sutherland A, et al
    Iodine-123 labeled reboxetine analogues for imaging of noradrenaline transporter in brain using single photon emission computed tomography.
    Synapse. 2012;66:923-30.
    PubMed     Text format     Related articles    Abstract available


    October 2012
  31. HARADA N , Ohba H, Kakiuchi T, Tsukada H, et al
    Application of feedback-controlled bolus plus infusion (FC-B/I) method for quantitative PET imaging of dopamine transporters with [(18) F]beta-CFT-FE in conscious monkey brain.
    Synapse. 2012 Oct 8. doi: 10.1002/syn.21614.
    PubMed     Text format     Related articles    Abstract available


  32. TAVARES AA , Barret O, Batis J, Alagille D, et al
    Kinetic modelling and occupancy measures of the norepinephrine transporters in baboons using SPECT with (123) I-INER.
    Synapse. 2012 Oct 8. doi: 10.1002/syn.21613.
    PubMed     Text format     Related articles    Abstract available


  33. PINBORG LH , Feng L, Haahr ME, Gillings N, et al
    No change in [(1)(1)C]CUMI-101 binding to 5-HT(1A) receptors after intravenous citalopram in human.
    Synapse. 2012;66:880-4.
    PubMed     Text format     Related articles    Abstract available


    September 2012
  34. MISHINA M , Kimura Y, Naganawa M, Ishii K, et al
    Differential effects of age on human striatal adenosine A(1) and A(2A) receptors.
    Synapse. 2012;66:832-9.
    PubMed     Text format     Related articles    Abstract available


  35. CHAO KT , Tsao HH, Weng YH, Hsiao IT, et al
    Quantitative analysis of binding sites for 9-fluoropropyl-(+)-dihydrotetrabenazine ([(1)(8)F]AV-133) in a MPTP-lesioned PD mouse model.
    Synapse. 2012;66:823-31.
    PubMed     Text format     Related articles    Abstract available


    August 2012
  36. HUANG Y , Narendran R, Bischoff F, Guo N, et al
    Synthesis and characterization of two PET radioligands for the metabotropic glutamate 1 (mGlu1) receptor.
    Synapse. 2012 Aug 28. doi: 10.1002/syn.21606.
    PubMed     Text format     Related articles    Abstract available


  37. MILLE E , Cumming P, Rominger A, La Fougere C, et al
    Compensation for cranial spill-in into the cerebellum improves quantitation of striatal dopamine D(2)/(3) receptors in rats with prolonged [(1)(8)F]-DMFP infusions.
    Synapse. 2012;66:705-13.
    PubMed     Text format     Related articles    Abstract available


    July 2012
  38. FUKUMOTO D , Nishiyama S, Harada N, Yamamoto S, et al
    Detection of ischemic neuronal damage with [(18) F]BMS-747158-02, a mitochondrial complex-1 PET ligand: Small animal pet study in rat brain.
    Synapse. 2012 Jul 18. doi: 10.1002/syn.21584.
    PubMed     Text format     Related articles    Abstract available


    June 2012
  39. KIMMEL HL , Nye JA, Voll R, Mun J, et al
    Simultaneous measurement of extracellular dopamine and dopamine transporter occupancy by cocaine analogs in squirrel monkeys.
    Synapse. 2012;66:501-8.
    PubMed     Text format     Related articles    Abstract available


  40. BRASIC JR , Bibat G, Kumar A, Zhou Y, et al
    Correlation of the vesicular acetylcholine transporter densities in the striata to the clinical abilities of women with Rett syndrome.
    Synapse. 2012;66:471-82.
    PubMed     Text format     Related articles    Abstract available


  41. GALLEZOT JD , Beaver JD, Gunn RN, Nabulsi N, et al
    Affinity and selectivity of [(1)(1)C]-(+)-PHNO for the D3 and D2 receptors in the rhesus monkey brain in vivo.
    Synapse. 2012;66:489-500.
    PubMed     Text format     Related articles    Abstract available


    April 2012
  42. EISENSTEIN SA , Koller JM, Piccirillo M, Kim A, et al
    Characterization of Extrastriatal D2 In VivoVivo Specific Binding of [(18) F](N-methyl)benperidol Using PET.
    Synapse. 2012 Apr 26. doi: 10.1002/syn.21566.
    PubMed     Text format     Related articles   


  43. DING M , Ghanekar S, Elmore CS, Zysk JR, et al
    [(3)H]Chiba-1001(methyl-SSR180711) has low in vitro binding affinity and poor in vivo selectivity to nicotinic alpha-7 receptor in rodent brain.
    Synapse. 2012;66:315-22.
    PubMed     Text format     Related articles    Abstract available


    January 2012
  44. ELMENHORST D , Aliaga A, Bauer A, Rosa-Neto P, et al
    Test-retest stability of cerebral mGluR(5) quantification using [(11) C]ABP688 and PET in rats.
    Synapse. 2012 Jan 31. doi: 10.1002/syn.21542.
    PubMed     Text format     Related articles    Abstract available


  45. TYACKE RJ , Fisher A, Robinson ES, Grundt P, et al
    Evaluation and initial in vitro and ex vivo characterisation of the potential positron emission tomography ligand, BU99008 (2-(4,5-Dihydro-1H-imidazol-2-yl)-1-methyl-1H-indole), for the Imidazoline(2) binding site.
    Synapse. 2012 Jan 31. doi: 10.1002/syn.21541.
    PubMed     Text format     Related articles    Abstract available


    December 2011
  46. BIESZCZAD KM , Kant R, Constantinescu CC, Pandey SK, et al
    Nicotinic acetylcholine receptors in rat forebrain that bind (18) F-nifene: Relating PET imaging, autoradiography and behavior.
    Synapse. 2011 Dec 28. doi: 10.1002/syn.21530.
    PubMed     Text format     Related articles    Abstract available


  47. BRASIC JR , Cascella N, Kumar A, Zhou Y, et al
    Positron emission tomography (PET) experience with 2-[(18) F]Fluoro-3-(2(S)-azetidinylmethoxy)pyridine (2-[(18) F]FA) in the living human brain of smokers with paranoid schizophrenia.
    Synapse. 2011 Dec 13. doi: 10.1002/syn.21520.
    PubMed     Text format     Related articles    Abstract available


    November 2011
  48. NAG S , Varrone A, Toth M, Thiele A, et al
    In vivo evaluation in cynomolgus monkey brain and metabolism of [(18) F]fluorodeprenyl a new MAO-B PET radioligand.
    Synapse. 2011 Nov 29. doi: 10.1002/syn.21514.
    PubMed     Text format     Related articles    Abstract available


    October 2011
  49. MARCELLINO D , Kehr J, Agnati LF, Fuxe K, et al
    Increased affinity of dopamine for D(2) -like versus D(1) -like receptors. Relevance for volume transmission in interpreting PET findings.
    Synapse. 2011 Oct 27. doi: 10.1002/syn.21501.
    PubMed     Text format     Related articles    Abstract available


    September 2011
  50. BOOT E , Booij J, Zinkstok JR, Baas F, et al
    COMT Val(158) met genotype and striatal D(2/3) receptor binding in adults with 22q11 deletion syndrome.
    Synapse. 2011;65:967-70.
    PubMed     Text format     Related articles    Abstract available


  51. CUMMING P
    Absolute abundances and affinity states of dopamine receptors in mammalian brain: A review.
    Synapse. 2011;65:892-909.
    PubMed     Text format     Related articles    Abstract available


    August 2011
  52. CONSTANTINESCU CC , Coleman RA, Pan ML, Mukherjee J, et al
    Striatal and extrastriatal microPET imaging of D2/D3 dopamine receptors in rat brain with [(1)F]fallypride and [(1)F]desmethoxyfallypride.
    Synapse. 2011;65:778-87.
    PubMed     Text format     Related articles    Abstract available


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