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  Parkinson's Disease

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Articles published in J Biol Chem

Retrieve available abstracts of 31 articles:
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    November 2016
  1. PFAFF DH, Fleming T, Nawroth P, Teleman AA, et al
    Evidence against a role for the Parkinsonism-associated protein DJ-1 in methylglyoxal detoxification.
    J Biol Chem. 2016 Nov 30. pii: jbc.M116.743823.
    PubMed     Text format     Abstract available


    September 2016
  2. YANG X, Mudgett J, Bou-About G, Champy MF, et al
    Physiological Expression of AMPKgamma2RG Mutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice.
    J Biol Chem. 2016 Sep 12. pii: jbc.M116.738591.
    PubMed     Text format     Abstract available


    July 2016
  3. FOLLETT J, Bugarcic A, Yang Z, Ariotti N, et al
    Parkinson's disease linked Vps35 R524W mutation impairs the endosomal association of retromer and induces alpha-synuclein aggregation.
    J Biol Chem. 2016 Jul 6. pii: jbc.M115.703157.
    PubMed     Text format     Abstract available


    June 2016
  4. KUMAR AS, Jagadeeshan S, Subramanian A, Chidambaram SB, et al
    Molecular Mechanism of Regulation of MTA1 Expression by Granulocyte Colony-stimulating Factor.
    J Biol Chem. 2016;291:12310-21.
    PubMed     Text format     Abstract available


    May 2016
  5. CHANDRA G, Rangasamy SB, Roy A, Kordower JH, et al
    Neutralization of regulated on activation, normal T cell expressed and secreted and eotaxin prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease.
    J Biol Chem. 2016 May 12. pii: jbc.M116.714824.
    PubMed     Text format     Abstract available


  6. LIU K, Li F, Han H, Chen Y, et al
    Parkin Regulates the Activity of Pyruvate Kinase M2.
    J Biol Chem. 2016;291:10307-17.
    PubMed     Text format     Abstract available


    March 2016
  7. FILOGRANA R, Godena VK, Sanchez-Martinez A, Ferrari E, et al
    SOD-mimetic M40403 is protective in cell and fly models of paraquat toxicity: Implications for Parkinson disease.
    J Biol Chem. 2016 Mar 7. pii: jbc.M115.708057.
    PubMed     Text format     Abstract available


    February 2016
  8. SAMUEL F, Flavin WP, Iqbal S, Pacelli C, et al
    Effects of Serine 129 Phosphorylation on alpha-Synuclein Aggregation, Membrane Association, and Internalization.
    J Biol Chem. 2016;291:4374-85.
    PubMed     Text format     Abstract available


    January 2016
  9. HAM SJ, Lee SY, Song S, Chung JR, et al
    Interaction between RING1 (R1) and the Ubiquitin-like (UBL) Domains Is Critical for the Regulation of Parkin Activity.
    J Biol Chem. 2016;291:1803-16.
    PubMed     Text format     Abstract available


  10. KIM H, Yang J, Kim MJ, Choi S, et al
    Tumor Necrosis Factor Receptor-associated Protein 1 (TRAP1) Mutation and TRAP1 Inhibitor Gamitrinib-triphenylphosphonium (G-TPP) Induce a Forkhead Box O (FOXO)-dependent Cell Protective Signal from Mitochondria.
    J Biol Chem. 2016;291:1841-53.
    PubMed     Text format     Abstract available


    December 2015
  11. PARK G, Tan J, Garcia G, Kang Y, et al
    Regulation of Histone Acetylation by Autophagy in Parkinson Disease.
    J Biol Chem. 2015 Dec 23. pii: jbc.M115.675488.
    PubMed     Text format     Abstract available


    November 2015
  12. MOREE B, Yin G, Lazaro DF, Munari F, et al
    Small Molecules Detected by Second-Harmonic Generation Modulate the Conformation of Monomeric alpha-Synuclein and Reduce Its Aggregation in Cells.
    J Biol Chem. 2015;290:27582-93.
    PubMed     Text format     Abstract available


  13. FOLLMER C, Coelho-Cerqueira E, Yatabe-Franco DY, Araujo GD, et al
    Oligomerization and Membrane-binding Properties of Covalent Adducts Formed by the Interaction of alpha-Synuclein with the Toxic Dopamine Metabolite 3,4-Dihydroxyphenylacetaldehyde (DOPAL).
    J Biol Chem. 2015;290:27660-79.
    PubMed     Text format     Abstract available


    August 2015
  14. DAHER JP, Abdelmotilib HA, Hu X, Volpicelli-Daley LA, et al
    Leucine-rich Repeat Kinase 2 (LRRK2) Pharmacological Inhibition Abates alpha-Synuclein Gene-induced Neurodegeneration.
    J Biol Chem. 2015;290:19433-44.
    PubMed     Text format     Abstract available


    June 2015
  15. ROSTOVTSEVA TK, Gurnev PA, Protchenko O, Hoogerheide DP, et al
    alpha-Synuclein Shows High-Affinity Interaction with Voltage-Dependent Anion Channel Suggesting Mechanisms of Mitochondrial Regulation and Toxicity in Parkinson Disease.
    J Biol Chem. 2015 Jun 8. pii: jbc.M115.641746.
    PubMed     Text format     Abstract available


    May 2015
  16. NORRIS KL, Hao R, Chen LF, Lai CH, et al
    Convergence of Parkin, PINK1, and alpha-Synuclein on Stress-induced Mitochondrial Morphological Remodeling.
    J Biol Chem. 2015;290:13862-74.
    PubMed     Text format     Abstract available


  17. CHAUDHURI AD, Kabaria S, Choi DC, Mouradian MM, et al
    MicroRNA-7 Promotes Glycolysis to Protect against 1-Methyl-4-phenylpyridinium-induced Cell Death.
    J Biol Chem. 2015;290:12425-34.
    PubMed     Text format     Abstract available


    April 2015
  18. HAN JY, Kang MJ, Kim KH, Han PL, et al
    Nitric oxide induction of Parkin translocation in PTEN-induced putative kinase 1 (PINK1) deficiency: functional role of neuronal nitric oxide synthase during mitophagy.
    J Biol Chem. 2015;290:10325-35.
    PubMed     Text format     Abstract available


    March 2015
  19. CHERUVARA H, Allen-Baume VL, Kad NM, Mason JM, et al
    Intracellular screening of a peptide library to derive a potent peptide inhibitor of alpha-synuclein aggregation.
    J Biol Chem. 2015;290:7426-35.
    PubMed     Text format     Abstract available


  20. SASAZAWA Y, Sato N, Umezawa K, Simizu S, et al
    Conophylline protects cells in cellular models of neurodegenerative diseases by inducing mammalian target of rapamycin (mTOR)-independent autophagy.
    J Biol Chem. 2015;290:6168-78.
    PubMed     Text format     Abstract available


    February 2015
  21. SAVOLAINEN MH, Yan X, Myohanen TT, Huttunen HJ, et al
    Prolyl oligopeptidase enhances alpha-synuclein dimerization via direct protein-protein interaction.
    J Biol Chem. 2015;290:5117-26.
    PubMed     Text format     Abstract available


  22. MBEFO M, Fares MB, Paleologou K, Oueslati A, et al
    The Parkinson's Disease Mutant E46K Enhances Alpha-Synuclein Phosphorylation in Mammalian Cell-Lines, in Yeast and In Vivo.
    J Biol Chem. 2015 Feb 5. pii: jbc.M114.610774.
    PubMed     Text format     Abstract available


  23. WADHWA R, Ryu J, Ahn HM, Saxena N, et al
    Functional Significance of Point Mutations in Stress Chaperone Mortalin and Their Relevance to Parkinson Disease.
    J Biol Chem. 2015 Feb 2. pii: jbc.M114.627463.
    PubMed     Text format     Abstract available


    January 2015
  24. GREY M, Dunning CJ, Gaspar R, Grey C, et al
    Acceleration of alpha-synuclein aggregation by exosomes.
    J Biol Chem. 2015;290:2969-82.
    PubMed     Text format     Abstract available


  25. SAHAY S, Ghosh D, Dwivedi S, Anoop A, et al
    Familial Parkinson's disease associated mutations alter the site-specific microenvironment and dynamics of alpha-Synuclein.
    J Biol Chem. 2015 Jan 29. pii: jbc.M114.598607.
    PubMed     Text format     Abstract available


  26. PORCARI R, Proukakis C, Waudby CA, Bolognesi B, et al
    The H50Q mutation induces a 10-fold decrease in the solubility of alpha-synuclein.
    J Biol Chem. 2015;290:2395-404.
    PubMed     Text format     Abstract available


  27. YAP TL, Jiang Z, Heinrich F, Gruschus JM, et al
    Structural features of membrane-bound glucocerebrosidase and alpha-synuclein probed by neutron reflectometry and fluorescence spectroscopy.
    J Biol Chem. 2015;290:744-54.
    PubMed     Text format     Abstract available


  28. LEE S, Zhang C, Liu X
    Role of glucose metabolism and ATP in maintaining PINK1 levels during Parkin-mediated mitochondrial damage responses.
    J Biol Chem. 2015;290:904-17.
    PubMed     Text format     Abstract available


    November 2014
  29. RICHARME G, Mihoub M, Dairou J, Bui LC, et al
    Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine and lysine residues.
    J Biol Chem. 2014 Nov 21. pii: jbc.M114.597815.
    PubMed     Text format     Abstract available


    August 2014
  30. YUN N, Lee YM, Kim C, Shibayama H, et al
    Anamorsin, a novel caspase-3 substrate in neurodegeneration.
    J Biol Chem. 2014;289:22183-95.
    PubMed     Text format     Abstract available


  31. KHALAF O, Fauvet B, Oueslati A, Dikiy I, et al
    The H50Q mutation enhances alpha-synuclein aggregation, secretion, and toxicity.
    J Biol Chem. 2014;289:21856-76.
    PubMed     Text format     Abstract available


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