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Pulmonary Hypertension

Free Subscription Articles published in Am J Physiol Lung Cell Mol Physiol Retrieve available abstracts of 72 articles: HTML format

Single Articles

April 2024
1. HATABAH D, De Marco T, McGlothlin DP, Malloy M, et al
   Low global arginine bioavailability: a common phenomenon in pulmonary hypertension.
   Am J Physiol Lung Cell Mol Physiol. 2024;326:L514-L515.
   PubMed    
   
   
   
2. ALI M, Choudhary R, Singh K, Kumari S, et al
   Hypobaric hypoxia modulated structural characteristics of circulating cell-free DNA in high-altitude pulmonary edema.
   Am J Physiol Lung Cell Mol Physiol. 2024;326:L496-L507.
   PubMed     Abstract available
   
   
   March 2024
3. PHILIP N, Yun X, Pi H, Murray S, et al
   Fatty acid metabolism promotes TRPV4 activity in lung microvascular endothelial cells in pulmonary arterial hypertension.
   Am J Physiol Lung Cell Mol Physiol. 2024;326:L252-L265.
   PubMed     Abstract available
   
   
   November 2023
4. SIMPSON CE, Ambade AS, Harlan R, Roux A, et al
   Kynurenine pathway metabolism evolves with development of preclinical and scleroderma-associated pulmonary arterial hypertension.
   Am J Physiol Lung Cell Mol Physiol. 2023;325:L617-L627.
   PubMed     Abstract available
   
   
   October 2023
5. BARNES EA, Ito R, Che X, Alvira CM, et al
   Loss of Prolyl Hydroxylase 1 and 2 in SM22alpha-Expressing Cells Prevents Hypoxia-Induced Pulmonary Hypertension.
   Am J Physiol Lung Cell Mol Physiol. 2023 Oct 17. doi: 10.1152/ajplung.00428.2022
   PubMed     Abstract available
   
   
   
6. LINGAPPAN K, Olutoye OO 2nd, Cantu A, Cantu Gutierrez ME, et al
   Molecular insights using spatial transcriptomics of the distal lung in congenital diaphragmatic hernia.
   Am J Physiol Lung Cell Mol Physiol. 2023;325:L477-L486.
   PubMed     Abstract available
   
   
   September 2023
7. PANKOKE S, Schweitzer T, Bikker R, Pich A, et al
   Obesity impacts hypoxia adaptation of the lung.
   Am J Physiol Lung Cell Mol Physiol. 2023;325:L352-L359.
   PubMed     Abstract available
   
   
   
8. ALMAZROUE H, Jin Y, Nelin LD, Barba JC 2nd, et al
   Human pulmonary microvascular endothelial cell DDAH1-mediated nitric oxide production promotes pulmonary smooth muscle cell apoptosis in co-culture.
   Am J Physiol Lung Cell Mol Physiol. 2023;325:L360-L367.
   PubMed     Abstract available
   
   
   August 2023
9. MASSON B, Saint-Martin Willer A, Dutheil M, Penalva L, et al
   Contribution of transient receptor potential canonical channels in human and experimental pulmonary arterial hypertension.
   Am J Physiol Lung Cell Mol Physiol. 2023;325:L246-L261.
   PubMed     Abstract available
   
   
   June 2023
10. DOUGHERTY EJ, Chen LY, Awad KS, Ferreyra GA, et al
    Inflammation and DKK1-induced AKT activation contribute to endothelial dysfunction following NR2F2 loss.
    Am J Physiol Lung Cell Mol Physiol. 2023;324:L783-L798.
    PubMed     Abstract available
    
    
    
11. SIMPSON CE, Coursen J, Hsu S, Gough EK, et al
    Metabolic profiling of in vivo right ventricular function and exercise performance in pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2023;324:L836-L848.
    PubMed     Abstract available
    
    
    May 2023
12. BIGNARD J, Atassi F, Claude O, Ghigna MR, et al
    T-cell dysregulation and inflammatory process in Gcn2 (Eif2ak4(-/-))-deficient rats in basal and stress conditions.
    Am J Physiol Lung Cell Mol Physiol. 2023;324:L609-L624.
    PubMed     Abstract available
    
    
    April 2023
13. GILBERT RM, Gleghorn JP
    Connecting clinical, environmental, and genetic factors point to an essential role for vitamin A signaling in the pathogenesis of congenital diaphragmatic hernia.
    Am J Physiol Lung Cell Mol Physiol. 2023;324:L456-L467.
    PubMed     Abstract available
    
    
    November 2022
14. SURESH K
    Sex as a biologic variable: evidence from isolated lung endothelial cells.
    Am J Physiol Lung Cell Mol Physiol. 2022;323:L646-L647.
    PubMed    
    
    
    August 2022
15. OSHITA H, Sawada H, Mitani Y, Tsuboya N, et al
    Perinatal hypoxia aggravates occlusive pulmonary vasculopathy in SU5416/hypoxia-treated rats later in life.
    Am J Physiol Lung Cell Mol Physiol. 2022;323:L178-L192.
    PubMed     Abstract available
    
    
    July 2022
16. CAMPBELL NV, Mickael C, Kumar S, Zhang H, et al
    Single-cell RNA sequencing and binary hierarchical clustering define lung interstitial macrophage heterogeneity in response to hypoxia.
    Am J Physiol Lung Cell Mol Physiol. 2022;323:L58-L68.
    PubMed     Abstract available
    
    
    June 2022
17. LEE MH, Sanders L, Kumar R, Hernandez-Saavedra D, et al
    Contribution of Fatty Acid Oxidation to the Pathogenesis of Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2022 Jun 28. doi: 10.1152/ajplung.00039.2022
    PubMed     Abstract available
    
    
    May 2022
18. CHEN J, Rodriguez M, Miao J, Liao J, et al
    Mechanosensitive channel Piezo1 is required for pulmonary artery smooth muscle cell proliferation.
    Am J Physiol Lung Cell Mol Physiol. 2022;322:L737-L760.
    PubMed     Abstract available
    
    
    March 2022
19. MAARMAN GJ
    Reviewing the suitability of mitochondrial transplantation as therapeutic approach for pulmonary hypertension in the era of personalised medicine.
    Am J Physiol Lung Cell Mol Physiol. 2022 Mar 23. doi: 10.1152/ajplung.00484.2021
    PubMed     Abstract available
    
    
    
20. LU M, Chen LY, Gairhe S, Mazer AJ, et al
    Mineralocorticoid receptor antagonist treatment of established pulmonary arterial hypertension improves interventricular dependence in the SU5416-hypoxia rat model.
    Am J Physiol Lung Cell Mol Physiol. 2022;322:L315-L332.
    PubMed     Abstract available
    
    
    February 2022
21. BAZAN IS, Ardito TA, Zhang Y, Shan P, et al
    Sex Differences and Altered Mitophagy in Experimental Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2022 Feb 9. doi: 10.1152/ajplung.00019.2020.
    PubMed     Abstract available
    
    
    October 2021
22. JAIN PP, Lai N, Xiong M, Chen J, et al
    TRPC6, a Therapeutic Target for Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2021 Oct 27. doi: 10.1152/ajplung.00159.2021
    PubMed     Abstract available
    
    
    September 2021
23. DE MAN FS, Vonk-Noordegraaf A
    The magic of communication: the need to study organ and cell communication in pulmonary arterial hypertension-induced right heart failure.
    Am J Physiol Lung Cell Mol Physiol. 2021;321:L634-L636.
    PubMed    
    
    
    August 2021
24. KASSA B, Kumar R, Mickael C, Sanders L, et al
    Endothelial Cell PHD2-HIF1alpha-PFKFB3 Contributes to Right Ventricle Vascular Adaptation in Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2021 Aug 4. doi: 10.1152/ajplung.00351.2020.
    PubMed     Abstract available
    
    
    
25. NAKAHARA M, Ito H, Skinner JT, Lin Q, et al
    The inflammatory role of dysregulated IRS2 in pulmonary vascular remodeling under hypoxic conditions.
    Am J Physiol Lung Cell Mol Physiol. 2021;321:L416-L428.
    PubMed     Abstract available
    
    
    July 2021
26. WESTOO C, Norvik C, Peruzzi N, van der Have O, et al
    Distinct types of plexiform lesions identified by synchrotron-based phase-contrast micro-CT.
    Am J Physiol Lung Cell Mol Physiol. 2021;321:L17-L28.
    PubMed     Abstract available
    
    
    June 2021
27. HYE T, Dwivedi P, Li W, Lahm T, et al
    Newer insights into the pathobiological and pharmacological basis of the sex disparity in patients with pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2021;320:L1025-L1037.
    PubMed     Abstract available
    
    
    May 2021
28. AULAK KS, Al Abdi S, Li L, Crabb JS, et al
    Disease-specific platelet signaling defects in idiopathic pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2021;320:L739-L749.
    PubMed     Abstract available
    
    
    
29. WOODCOCK CC, Hafeez N, Handen A, Tang Y, et al
    Matrix stiffening induces a pathogenic QKI-miR-7-SRSF1 signaling axis in pulmonary arterial endothelial cells.
    Am J Physiol Lung Cell Mol Physiol. 2021;320:L726-L738.
    PubMed     Abstract available
    
    
    March 2021
30. HADZIC S, Wu CY, Gredic M, Kojonazarov B, et al
    The effect of long-term doxycycline treatment in a mouse model of cigarette smoke-induced emphysema and pulmonary hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2021 Mar 24. doi: 10.1152/ajplung.00048.2021
    PubMed     Abstract available
    
    
    
31. RICHTER MJ, Hsu S, Yogeswaran A, Husain-Syed F, et al
    Right ventricular pressure-volume loop shape and systolic pressure change in pulmonary hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2021 Mar 3. doi: 10.1152/ajplung.00583.2020.
    PubMed     Abstract available
    
    
    January 2021
32. VALUPARAMPIL VARGHESE M, James J, Rafikova O, Rafikov R, et al
    Glucose-6 Phosphate dehydrogenase deficiency contributes to metabolic abnormality and pulmonary hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2021 Jan 27. doi: 10.1152/ajplung.00165.2020
    PubMed     Abstract available
    
    
    December 2020
33. SHRESTHA AK, Menon RT, El-Saie A, Barrios R, et al
    Interactive and independent effects of early lipopolysaccharide and hyperoxia exposure on developing murine lungs.
    Am J Physiol Lung Cell Mol Physiol. 2020;319:L981-L996.
    PubMed     Abstract available
    
    
    November 2020
34. YUAN C, Chen HX, Hou HT, Wang J, et al
    Protein biomarkers and risk scores in pulmonary arterial hypertension associated with ventricular septal defect: integration of multi-omics and validation.
    Am J Physiol Lung Cell Mol Physiol. 2020;319:L810-L822.
    PubMed     Abstract available
    
    
    October 2020
35. CALLEJO M, Mondejar-Parreno G, Morales-Cano D, Barreira B, et al
    Vitamin D deficiency downregulates TASK-1 channels and induces pulmonary vascular dysfunction.
    Am J Physiol Lung Cell Mol Physiol. 2020;319:L627-L640.
    PubMed     Abstract available
    
    
    September 2020
36. SHEAK JR, Jones DT, Lantz BJ, Maston LD, et al
    NFATc3 Regulation of Collagen V Expression Contributes to Cellular Immunity to Collagen Type V and Hypoxic Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2020 Sep 30. doi: 10.1152/ajplung.00184.2020
    PubMed     Abstract available
    
    
    
37. TAN R, Li J, Liu F, Liao P, et al
    Phenylalanine Induces Pulmonary Hypertension Through Calcium-Sensing Receptor Activation.
    Am J Physiol Lung Cell Mol Physiol. 2020 Sep 23. doi: 10.1152/ajplung.00215.2020
    PubMed     Abstract available
    
    
    
38. LAHM T
    Taking it to heart: dissecting cardiopulmonary interactions in diseases of the lung and the cardiovascular system.
    Am J Physiol Lung Cell Mol Physiol. 2020;319:L547-L549.
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39. LIN Q, Johns RA
    Resistin family proteins in pulmonary diseases.
    Am J Physiol Lung Cell Mol Physiol. 2020;319:L422-L434.
    PubMed     Abstract available
    
    
    
40. KRISHNAN S, Stearman RS, Zeng L, Fisher A, et al
    Transcriptomic modifications in developmental cardiopulmonary adaptations to chronic hypoxia using a murine model of simulated high-altitude exposure.
    Am J Physiol Lung Cell Mol Physiol. 2020;319:L456-L470.
    PubMed     Abstract available
    
    
    August 2020
41. ALAM P, Agarwal G, Kumar R, Mishra A, et al
    Susceptibility to high-altitude pulmonary edema is associated with circulating miRNA levels under hypobaric hypoxia conditions.
    Am J Physiol Lung Cell Mol Physiol. 2020;319:L360-L368.
    PubMed     Abstract available
    
    
    June 2020
42. SZULCEK R, Grune J, Kuebler WM
    The updated cancer paradigm of PAH: recognizing complexity.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L1111-L1114.
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43. LEE JY, Francis CM, Bauer NN, Gassman NR, et al
    A cancer amidst us: the plexiform lesion in pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L1142-L1144.
    PubMed    
    
    
    
44. FRUMP AL, Lai YC, Lahm T
    Assessing the cancer hypothesis of pulmonary arterial hypertension: the devil is in the detail.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L1140-L1141.
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45. CONDON D, Agarwal S, Chakraborty A, de Jesus Perez VA, et al
    The cancer hypothesis of pulmonary arterial hypertension: the next ten years.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L1138-L1139.
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46. COOL CD, Kuebler WM, Bogaard HJ, Spiekerkoetter E, et al
    The hallmarks of severe pulmonary arterial hypertension: the cancer hypothesis-ten years later.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L1115-L1130.
    PubMed     Abstract available
    
    
    May 2020
47. AGARWAL S, Sharma H, Chen L, Dhillon NK, et al
    NADPH oxidase-mediated endothelial injury in HIV- and opioid-induced pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L1097-L1108.
    PubMed     Abstract available
    
    
    
48. GIE AG, Salaets T, Vignero J, Regin Y, et al
    Intermittent CPAP limits hyperoxia-induced lung damage in a rabbit model of bronchopulmonary dysplasia.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L976-L987.
    PubMed     Abstract available
    
    
    April 2020
49. MORTY RE
    World health days in May 2020: Pulmonary hypertension, asthma, and tobacco-, smoking-, and vaping-related disease in focus.
    Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1. doi: 10.1152/ajplung.00115.2020.
    PubMed    
    
    
    
50. SHIMODA LA
    Know Your Enemy: Understanding the Pathophysiology of Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1. doi: 10.1152/ajplung.00111.2020.
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51. CORRIS PA, Seeger W
    Call it by the correct name - pulmonary hypertension not pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1. doi: 10.1152/ajplung.00098.2020.
    PubMed    
    
    
    March 2020
52. TUDER RM, Stenmark KR
    Perspective: Pathobiological paradigms in pulmonary hypertension, time for reappraisal.
    Am J Physiol Lung Cell Mol Physiol. 2020 Mar 18. doi: 10.1152/ajplung.00067.2020
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53. JOSHI SR, Kitagawa A, Jacob C, Hashimoto R, et al
    Hypoxic Activation of G6PD Controls the Expression of Genes Involved in the Pathogenesis of Pulmonary Hypertension Through the Regulation of DNA Methylation.
    Am J Physiol Lung Cell Mol Physiol. 2020 Mar 11. doi: 10.1152/ajplung.00001.2020
    PubMed     Abstract available
    
    
    
54. MCDOWELL RE, Aulak KS, Almoushref A, Melillo CA, et al
    Platelet glycolytic metabolism correlates with hemodynamic severity in pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L562-L569.
    PubMed     Abstract available
    
    
    February 2020
55. DIKALOVA A, Aschner JL, Kaplowitz MR, Cunningham G, et al
    Combined L-citrulline and tetrahydrobiopterin therapy improves NO signaling and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs.
    Am J Physiol Lung Cell Mol Physiol. 2020 Feb 19. doi: 10.1152/ajplung.00280.2019
    PubMed     Abstract available
    
    
    January 2020
56. ARJAANS S, Wagner BD, Mourani PM, Mandell EW, et al
    Early Angiogenic Proteins Associated with High Risk for Bronchopulmonary Dysplasia and Pulmonary Hypertension in Preterm Infants.
    Am J Physiol Lung Cell Mol Physiol. 2020 Jan 22. doi: 10.1152/ajplung.00131.2019
    PubMed     Abstract available
    
    
    
57. HASHIMOTO R, Lanier GM, Dhagia V, Joshi S, et al
    Pluripotent HSCs Augment a-Adrenergic Receptor-Mediated Contraction of Pulmonary Artery and Contribute to the Pathogenesis of Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2020 Jan 8. doi: 10.1152/ajplung.00327.2019.
    PubMed     Abstract available
    
    
    
58. ELINOFF JM, Mazer AJ, Cai R, Lu M, et al
    Meta-analysis of blood genome-wide expression profiling studies in pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L98-L111.
    PubMed     Abstract available
    
    
    
59. NORVIK C, Westoo CK, Peruzzi N, Lovric G, et al
    Synchrotron-based phase-contrast micro-CT as a tool for understanding pulmonary vascular pathobiology and the 3-D microanatomy of alveolar capillary dysplasia.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L65-L75.
    PubMed     Abstract available
    
    
    
60. BABICHEVA A, Ayon RJ, Zhao T, Ek Vitorin JF, et al
    MicroRNA-mediated downregulation of K(+) channels in pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2020;318:L10-L26.
    PubMed     Abstract available
    
    
    December 2019
61. HE S, Ma C, Zhang L, Bai J, et al
    GLI1 mediated pulmonary artery smooth muscle cell pyroptosis contributes to hypoxia induced pulmonary hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2019 Dec 23. doi: 10.1152/ajplung.00405.2019
    PubMed     Abstract available
    
    
    November 2019
62. CUSSAC LA, Cardouat G, Tiruchellvam Pillai N, Campagnac M, et al
    TRPV4 channel mediates adventitial fibroblast activation and adventitial remodeling in pulmonary hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2019 Nov 6. doi: 10.1152/ajplung.00084.2019.
    PubMed     Abstract available
    
    
    October 2019
63. JALCE G, Guignabert C
    The Multiple Roles of Macrophage Migration Inhibitory Factor in Pulmonary Hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2019 Oct 2. doi: 10.1152/ajplung.00234.2019.
    PubMed     Abstract available
    
    
    August 2019
64. PAUL T, Blanco I, Aguilar D, Tura-Ceide O, et al
    Therapeutic effects of soluble guanylate cyclase stimulation on pulmonary hemodynamics and emphysema development in guinea pigs chronically exposed to cigarette smoke.
    Am J Physiol Lung Cell Mol Physiol. 2019;317:L222-L234.
    PubMed     Abstract available
    
    
    July 2019
65. CHANG CJ, Hsu HC, Ho WJ, Chang GJ, et al
    Cathepsin S promotes the development of pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2019;317:L1-L13.
    PubMed     Abstract available
    
    
    June 2019
66. HAO R, Song Y, Li R, Wu Y, et al
    MLN4924 protects against interleukin-17A-induced pulmonary inflammation by disrupting ACT1-mediated signaling.
    Am J Physiol Lung Cell Mol Physiol. 2019;316:L1070-L1080.
    PubMed     Abstract available
    
    
    
67. KIPFMUELLER F, Heindel K, Geipel A, Berg C, et al
    Expression of soluble receptor for advanced glycation end products is associated with disease severity in congenital diaphragmatic hernia.
    Am J Physiol Lung Cell Mol Physiol. 2019;316:L1061-L1069.
    PubMed     Abstract available
    
    
    May 2019
68. XIAO R, Zhu L, Su Y, Zhang J, et al
    Monocrotaline pyrrole induces pulmonary endothelial damage through binding to and release from erythrocytes in lung during venous blood reoxygenation.
    Am J Physiol Lung Cell Mol Physiol. 2019;316:L798-L809.
    PubMed     Abstract available
    
    
    
69. HOGAN SE, Rodriguez Salazar MP, Cheadle J, Glenn R, et al
    Mesenchymal stromal cell-derived exosomes improve mitochondrial health in pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2019;316:L723-L737.
    PubMed     Abstract available
    
    
    March 2019
70. MOURADIAN GC JR, Alvarez-Argote S, Gorzek R, Thuku G, et al
    Acute and chronic changes in the control of breathing in a rat model of bronchopulmonary dysplasia.
    Am J Physiol Lung Cell Mol Physiol. 2019;316:L506-L518.
    PubMed     Abstract available
    
    
    
71. QUATREDENIERS M, Nakhleh MK, Dumas SJ, Courboulin A, et al
    Functional interaction between PDGFbeta and GluN2B-containing NMDA receptors in smooth muscle cell proliferation and migration in pulmonary arterial hypertension.
    Am J Physiol Lung Cell Mol Physiol. 2019;316:L445-L455.
    PubMed     Abstract available
    
    
    January 2019
72. RASHID J, Nozik-Grayck E, McMurtry IF, Stenmark KR, et al
    Inhaled combination of sildenafil and rosiglitazone improves pulmonary hemodynamics, cardiac function, and arterial remodeling.
    Am J Physiol Lung Cell Mol Physiol. 2019;316:L119-L130.
    PubMed     Abstract available
    
    

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