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The Medical Article of the Year 2008:
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447:661-78.
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  Schizophrenia

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Articles published in Mol Psychiatry

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Single Articles


    July 2008
  1. BURNET PW , Eastwood SL, Bristow GC, Godlewska BR, et al
    D-amino acid oxidase activity and expression are increased in schizophrenia.
    Mol Psychiatry. 2008;13:658-60.
    PubMed     Related articles   


    June 2008
  2. VOLPI S , Heaton C, Mack K, Hamilton JB, et al
    Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia.
    Mol Psychiatry. 2008;.
    PubMed     Related articles    Abstract available


    May 2008
  3. SMALLA KH , Mikhaylova M, Sahin J, Bernstein HG, et al
    A comparison of the synaptic proteome in human chronic schizophrenia and rat ketamine psychosis suggest that prohibitin is involved in the synaptic pathology of schizophrenia.
    Mol Psychiatry. 2008;.
    PubMed     Related articles    Abstract available


    April 2008
  4. ROMERO E , Guaza C, Castellano B, Borrell J, et al
    Ontogeny of sensorimotor gating and immune impairment induced by prenatal immune challenge in rats: implications for the etiopathology of schizophrenia.
    Mol Psychiatry. 2008;.
    PubMed     Related articles    Abstract available


  5. ZHOU X , Geyer MA, Kelsoe JR
    Does disrupted-in-schizophrenia (DISC1) generate fusion transcripts?
    Mol Psychiatry. 2008;13:361-3.
    PubMed     Related articles   


  6. SEQUEIRA A , Meng F, Rollins B, Myers RM, et al
    Coding SNPs included in exon arrays for the study of psychiatric disorders.
    Mol Psychiatry. 2008;13:363-5.
    PubMed     Related articles   


    March 2008
  7. SULLIVAN PF , Lin D, Tzeng JY, van den Oord E, et al
    Genomewide association for schizophrenia in the CATIE study: results of stage 1.
    Mol Psychiatry. 2008;.
    PubMed     Related articles    Abstract available


  8. GLATT SJ , Faraone SV, Lasky-Su JA, Kanazawa T, et al
    Family-based association testing strongly implicates DRD2 as a risk gene for schizophrenia in Han Chinese from Taiwan.
    Mol Psychiatry. 2008;.
    PubMed     Related articles    Abstract available


  9. KIROV G , Zaharieva I, Georgieva L, Moskvina V, et al
    A genome-wide association study in 574 schizophrenia trios using DNA pooling.
    Mol Psychiatry. 2008;.
    PubMed     Related articles    Abstract available


  10. HENNAH W , Thomson P, McQuillin A, Bass N, et al
    DISC1 association, heterogeneity and interplay in schizophrenia and bipolar disorder.
    Mol Psychiatry. 2008;.
    PubMed     Related articles    Abstract available


  11. PICKARD BS , Christoforou A, Thomson PA, Fawkes A, et al
    Interacting haplotypes at the NPAS3 locus alter risk of schizophrenia and bipolar disorder.
    Mol Psychiatry. 2008;.
    PubMed     Related articles    Abstract available


  12. SCARR E , Cowie TF, Kanellakis S, Sundram S, et al
    Decreased cortical muscarinic receptors define a subgroup of subjects with schizophrenia.
    Mol Psychiatry. 2008;.
    PubMed     Related articles    Abstract available


  13. MURRAY GK , Corlett PR, Clark L, Pessiglione M, et al
    How dopamine dysregulation leads to psychotic symptoms? Abnormal mesolimbic and mesostriatal prediction error signalling in psychosis.
    Mol Psychiatry. 2008;13:239.
    PubMed     Related articles   


  14. TAN HY , Callicott JH, Weinberger DR
    Intermediate phenotypes in schizophrenia genetics redux: is it a no brainer?
    Mol Psychiatry. 2008;13:233-8.
    PubMed     Related articles   


    February 2008
  15. YOLKEN RH , Torrey EF
    Are some cases of psychosis caused by microbial agents? A review of the evidence.
    Mol Psychiatry. 2008;.
    PubMed     Related articles    Abstract available


  16. BEHAN A , Byrne C, Dunn MJ, Cagney G, et al
    Proteomic analysis of membrane microdomain-associated proteins in the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder reveals alterations in LAMP, STXBP1 and BASP1 protein expression.
    Mol Psychiatry. 2008;.
    PubMed     Related articles    Abstract available


  17. KAO HT , Cawthon RM, Delisi LE, Bertisch HC, et al
    Rapid telomere erosion in schizophrenia.
    Mol Psychiatry. 2008;13:118-9.
    PubMed     Related articles   


    January 2008
  18. LE HELLARD S , Theisen FM, Haberhausen M, Raeder MB, et al
    Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?
    Mol Psychiatry. 2008;.
    PubMed     Related articles    Abstract available


  19. NICODEMUS KK , Marenco S, Batten AJ, Vakkalanka R, et al
    Serious obstetric complications interact with hypoxia-regulated/vascular-expression genes to influence schizophrenia risk.
    Mol Psychiatry. 2008;.
    PubMed     Related articles    Abstract available


    December 2007
  20. RENOU J , De Luca V, Zai CC, Bulgin N, et al
    Multiple variants of the DRD3, but not BDNF gene, influence age-at-onset of schizophrenia.
    Mol Psychiatry. 2007;12:1058-60.
    PubMed     Related articles   


    October 2007
  21. PENNINGTON K , Beasley CL, Dicker P, Fagan A, et al
    Prominent synaptic and metabolic abnormalities revealed by proteomic analysis of the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  22. HUANG JT , Wang L, Prabakaran S, Wengenroth M, et al
    Independent protein-profiling studies show a decrease in apolipoprotein A1 levels in schizophrenia CSF, brain and peripheral tissues.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  23. KAROUTZOU G , Emrich HM, Dietrich DE
    The myelin-pathogenesis puzzle in schizophrenia: a literature review.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  24. HORIUCHI Y , Ishiguro H, Koga M, Inada T, et al
    Support for association of the PPP3CC gene with schizophrenia.
    Mol Psychiatry. 2007;12:891-893.
    PubMed     Related articles   


    September 2007
  25. JUNGERIUS BJ , Hoogendoorn ML, Bakker SC, Van't Slot R, et al
    An association screen of myelin-related genes implicates the chromosome 22q11 PIK4CA gene in schizophrenia.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  26. PLETNIKOV MV , Ayhan Y, Nikolskaia O, Xu Y, et al
    Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  27. NICODEMUS KK , Luna A, Vakkalanka R, Goldberg T, et al
    Further evidence for association between ErbB4 and schizophrenia and influence on cognitive intermediate phenotypes in healthy controls.
    Mol Psychiatry. 2007;12:883.
    PubMed     Related articles   


  28. BELLON A
    New genes associated with schizophrenia in neurite formation: a review of cell culture experiments.
    Mol Psychiatry. 2007;12:882.
    PubMed     Related articles   


  29. STRAUB RE , Lipska BK, Egan MF, Goldberg TE, et al
    Allelic variation in GAD1 (GAD(67)) is associated with schizophrenia and influences cortical function and gene expression.
    Mol Psychiatry. 2007;12:854-69.
    PubMed     Related articles    Abstract available


  30. DONOHOE G , Morris DW, Robertson IH, McGhee KA, et al
    DAOA ARG30LYS and verbal memory function in schizophrenia.
    Mol Psychiatry. 2007;12:795-6.
    PubMed     Related articles   


  31. ZAI CC , De Luca V, Hwang RW, Voineskos A, et al
    Meta-analysis of two dopamine D(2) receptor gene polymorphisms with tardive dyskinesia in schizophrenia patients.
    Mol Psychiatry. 2007;12:794-5.
    PubMed     Related articles   


    August 2007
  32. WEDENOJA J , Loukola A, Tuulio-Henriksson A, Paunio T, et al
    Replication of linkage on chromosome 7q22 and association of the regional Reelin gene with working memory in schizophrenia families.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  33. KVAJO M , Dhilla A, Swor DE, Karayiorgou M, et al
    Evidence implicating the candidate schizophrenia/bipolar disorder susceptibility gene G72 in mitochondrial function.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  34. WIEDHOLZ LM , Owens WA, Horton RE, Feyder M, et al
    Mice lacking the AMPA GluR1 receptor exhibit striatal hyperdopaminergia and 'schizophrenia-related' behaviors.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  35. MURRAY GK , Corlett PR, Clark L, Pessiglione M, et al
    Substantia nigra/ventral tegmental reward prediction error disruption in psychosis.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


    July 2007
  36. MCOMISH CE , Burrows E, Howard M, Scarr E, et al
    Phospholipase C-beta1 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  37. CHEN Q , Wang X, O'neill FA, Walsh D, et al
    Association study of CSF2RB with schizophrenia in Irish family and case - control samples.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  38. FRANCKS C , Maegawa S, Lauren J, Abrahams BS, et al
    LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  39. GRAY JA , Roth BL
    The pipeline and future of drug development in schizophrenia.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  40. FRIEDMAN JI , Vrijenhoek T, Markx S, Janssen IM, et al
    CNTNAP2 gene dosage variation is associated with schizophrenia and epilepsy.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


    June 2007
  41. ARRANZ MJ , de Leon J
    Pharmacogenetics and pharmacogenomics of schizophrenia: a review of last decade of research.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  42. LENCZ T , Morgan TV, Athanasiou M, Dain B, et al
    Converging evidence for a pseudoautosomal cytokine receptor gene locus in schizophrenia.
    Mol Psychiatry. 2007;12:572-580.
    PubMed     Related articles    Abstract available


  43. TAMURA Y , Kunugi H, Ohashi J, Hohjoh H, et al
    Epigenetic aberration of the human REELIN gene in psychiatric disorders.
    Mol Psychiatry. 2007;12:519.
    PubMed     Related articles    Abstract available


    May 2007
  44. VLADIMIROV V , Thiselton DL, Kuo PH, McClay J, et al
    A region of 35 kb containing the trace amine associate receptor 6 (TAAR6) gene is associated with schizophrenia in the Irish study of high-density schizophrenia families.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  45. HASHIMOTO T , Arion D, Unger T, Maldonado-Aviles JG, et al
    Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


    April 2007
  46. ROJAS P , Joodmardi E, Hong Y, Perlmann T, et al
    Adult mice with reduced Nurr1 expression: an animal model for schizophrenia.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  47. CHRISTOFOROU A , Le Hellard S, Thomson PA, Morris SW, et al
    Association analysis of the chromosome 4p15-p16 candidate region for bipolar disorder and schizophrenia.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  48. BELLON A
    New genes associated with schizophrenia in neurite formation: a review of cell culture experiments.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  49. SEI Y , Ren-Patterson R, Li Z, Tunbridge EM, et al
    Neuregulin1-induced cell migration is impaired in schizophrenia: association with neuregulin1 and catechol-o-methyltransferase gene polymorphisms.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  50. ROIG B , Virgos C, Franco N, Martorell L, et al
    The discoidin domain receptor 1 as a novel susceptibility gene for schizophrenia.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  51. FANOUS AH , Neale MC, Gardner CO, Webb BT, et al
    Significant correlation in linkage signals from genome-wide scans of schizophrenia and schizotypy.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  52. CHAVARRIA-SILES I , Walss-Bass C, Quezada P, Dassori A, et al
    TGFB-induced factor (TGIF): a candidate gene for psychosis on chromosome 18p.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  53. KADDURAH-DAOUK R , McEvoy J, Baillie RA, Lee D, et al
    Metabolomic mapping of atypical antipsychotic effects in schizophrenia.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  54. BUXBAUM JD , Georgieva L, Young JJ, Plescia C, et al
    Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility gene.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  55. SKELLY T , Pinheiro AP, Lange LA, Sullivan PF, et al
    Is rs7566605, a SNP near INSIG2, associated with body mass in a randomized clinical trial of antipsychotics in schizophrenia?
    Mol Psychiatry. 2007;12:321-2.
    PubMed     Related articles   


  56. JARDRI R , Lucas B, Delevoye-Turrell Y, Delmaire C, et al
    An 11-year-old boy with drug-resistant schizophrenia treated with temporo-parietal rTMS.
    Mol Psychiatry. 2007;12:320.
    PubMed     Related articles   


  57. JARDRI R , Pins D, Delmaire C, Goeb JL, et al
    Activation of bilateral auditory cortex during verbal hallucinations in a child with schizophrenia.
    Mol Psychiatry. 2007;12:319.
    PubMed     Related articles   


    March 2007
  58. HASHIMOTO R , Hashimoto H, Shintani N, Chiba S, et al
    Pituitary adenylate cyclase-activating polypeptide is associated with schizophrenia.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  59. LIU YL , Fann CS, Liu CM, Chang CC, et al
    More evidence supports the association of PPP3CC with schizophrenia.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


    February 2007
  60. BARNETT JH , Jones PB, Robbins TW, Muller U, et al
    Effects of the catechol-O-methyltransferase Val(158)Met polymorphism on executive function: a meta-analysis of the Wisconsin Card Sort Test in schizophrenia and healthy controls.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  61. RUJESCU D , Meisenzahl EM, Krejcova S, Giegling I, et al
    Plexin B3 is genetically associated with verbal performance and white matter volume in human brain.
    Mol Psychiatry. 2007;12:190-4.
    PubMed     Related articles    Abstract available


    January 2007
  62. RUZICKA WB , Zhubi A, Veldic M, Grayson DR, et al
    Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  63. KNIGHT JG , Menkes DB, Highton J, Adams DD, et al
    Rationale for a trial of immunosuppressive therapy in acute schizophrenia.
    Mol Psychiatry. 2007;.
    PubMed     Related articles    Abstract available


  64. PRASAD KM , Shirts BH, Yolken RH, Keshavan MS, et al
    HSV1 exposure affects prefrontal cortical structure in schizophrenia patients.
    Mol Psychiatry. 2007;12:1.
    PubMed     Related articles   


    December 2006
  65. CHEN X , Wang X, Hossain S, O'neill FA, et al
    Interleukin 3 and schizophrenia: the impact of sex and family history.
    Mol Psychiatry. 2006;.
    PubMed     Related articles    Abstract available


  66. RAEDLER TJ , Bymaster FP, Tandon R, Copolov D, et al
    Towards a muscarinic hypothesis of schizophrenia.
    Mol Psychiatry. 2006;.
    PubMed     Related articles    Abstract available


  67. NICODEMUS KK , Luna A, Vakkalanka R, Goldberg T, et al
    Further evidence for association between ErbB4 and schizophrenia and influence on cognitive intermediate phenotypes in healthy controls.
    Mol Psychiatry. 2006;11:1062-5.
    PubMed     Related articles   


    November 2006
  68. FELLERHOFF B , Laumbacher B, Mueller N, Gu S, et al
    Associations between Chlamydophila infections, schizophrenia and risk of HLA-A10.
    Mol Psychiatry. 2006;.
    PubMed     Related articles    Abstract available


  69. HARRISON PJ , West VA
    Six degrees of separation: on the prior probability that schizophrenia susceptibility genes converge on synapses, glutamate and NMDA receptors.
    Mol Psychiatry. 2006;11:981-3.
    PubMed     Related articles   


    October 2006
  70. CAMARGO LM , Collura V, Rain JC, Mizuguchi K, et al
    Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.
    Mol Psychiatry. 2006;.
    PubMed     Related articles    Abstract available


  71. ADDINGTON AM , Gornick MC, Shaw P, Seal J, et al
    Neuregulin 1 (8p12) and childhood-onset schizophrenia: susceptibility haplotypes for diagnosis and brain developmental trajectories.
    Mol Psychiatry. 2006;.
    PubMed     Related articles    Abstract available


  72. EHRENREICH H , Hinze-Selch D, Stawicki S, Aust C, et al
    Improvement of cognitive functions in chronic schizophrenic patients by recombinant human erythropoietin.
    Mol Psychiatry. 2006;.
    PubMed     Related articles    Abstract available


  73. PRASAD KM , Shirts BH, Yolken RH, Keshavan MS, et al
    Brain morphological changes associated with exposure to HSV1 in first-episode schizophrenia.
    Mol Psychiatry. 2006;.
    PubMed     Related articles    Abstract available


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