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Articles published in Am J Respir Crit Care Med

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Single Articles


    October 2017
  1. GOTTS JE, Matthay MA
    Cell-based Therapy in Sepsis: A Step Closer.
    Am J Respir Crit Care Med. 2017 Oct 26. doi: 10.1164/rccm.201710-2068.
    PubMed     Text format    


  2. PATEL JJ, Rosenthal MD, McClave SA, Martindale RG, et al
    Tempering the Clinical Effects of Early Myeloid Derived Suppressor Cell Expansion in Severe Sepsis and Septic Shock.
    Am J Respir Crit Care Med. 2017 Oct 6. doi: 10.1164/rccm.201708-1701.
    PubMed     Text format    


  3. UHEL F, Camus C, Gacouin A, Tadie JM, et al
    Reply to: Tempering the Clinical Effects of Early Myeloid Derived Suppressor Cell Expansion in Severe Sepsis and Septic Shock.
    Am J Respir Crit Care Med. 2017 Oct 6. doi: 10.1164/rccm.201709-1854.
    PubMed     Text format    


  4. SCICLUNA BP, Wiewel MA, van Vught LA, Hoogendijk AJ, et al
    A Molecular Biomarker to Assist in Diagnosing Abdominal Sepsis Upon Intensive Care Unit Admission.
    Am J Respir Crit Care Med. 2017 Oct 3. doi: 10.1164/rccm.201707-1339.
    PubMed     Text format    


    September 2017
  5. SHEA BS, Opal SM
    The Role of S1PR3 in Protection from Bacterial Sepsis.
    Am J Respir Crit Care Med. 2017 Sep 14. doi: 10.1164/rccm.201708-1726.
    PubMed     Text format    


  6. RANZANI OT, Torres A
    Reply to: Sepsis-3 in Community-acquired Pneumonia: How Reliable is It?
    Am J Respir Crit Care Med. 2017 Sep 11. doi: 10.1164/rccm.201708-1598.
    PubMed     Text format    


  7. AKINOSOGLOU K, Gogos C
    Sepsis-3 in Community-acquired Pneumonia: How Reliable is It?
    Am J Respir Crit Care Med. 2017 Sep 11. doi: 10.1164/rccm.201707-1414.
    PubMed     Text format    


  8. LAVAL J, Singh A, Hartl D
    Autophagy Traps Neutrophils into a Protective Alliance during Sepsis.
    Am J Respir Crit Care Med. 2017;196:537-538.
    PubMed     Text format    


    August 2017
  9. HOU J, Chen Q, Wu X, Zhao D, et al
    S1PR3 Signaling Drives Bactericidal Killing and is Required for Survival in Bacterial Sepsis.
    Am J Respir Crit Care Med. 2017 Aug 29. doi: 10.1164/rccm.201701-0241.
    PubMed     Text format     Abstract available


  10. PICKKERS P
    Simultaneously Mounted Pro- and Anti-inflammatory Host Response Relates to the Development of Secondary Infections in Patients with Sepsis.
    Am J Respir Crit Care Med. 2017;196:406-407.
    PubMed     Text format    


  11. WONG HR, Cvijanovich NZ, Anas N, Allen GL, et al
    Improved Risk Stratification in Pediatric Septic Shock Using Both Protein and mRNA Biomarkers. PERSEVERE-XP.
    Am J Respir Crit Care Med. 2017;196:494-501.
    PubMed     Text format     Abstract available


  12. VAN DER POLL T
    Myeloid-derived Suppressor Cells in Sepsis.
    Am J Respir Crit Care Med. 2017;196:256-258.
    PubMed     Text format    


  13. WONG HR, Marshall JC
    Leveraging Transcriptomics to Disentangle Sepsis Heterogeneity.
    Am J Respir Crit Care Med. 2017;196:258-260.
    PubMed     Text format    


  14. UHEL F, Azzaoui I, Gregoire M, Pangault C, et al
    Early Expansion of Circulating Granulocytic Myeloid-derived Suppressor Cells Predicts Development of Nosocomial Infections in Patients with Sepsis.
    Am J Respir Crit Care Med. 2017;196:315-327.
    PubMed     Text format     Abstract available


    June 2017
  15. RANZANI OT, Prina E, Menendez R, Ceccato A, et al
    New Sepsis Definition (Sepsis-3) and Community-acquired Pneumonia Mortality: A Validation and Clinical Decision-making Study.
    Am J Respir Crit Care Med. 2017 Jun 14. doi: 10.1164/rccm.201611-2262.
    PubMed     Text format     Abstract available


    May 2017
  16. ZEIN JG, Love TE, Erzurum SC
    Asthma is Associated with a Lower Risk of Sepsis and Sepsis Related Mortality.
    Am J Respir Crit Care Med. 2017 May 22. doi: 10.1164/rccm.201608-1583.
    PubMed     Text format    


  17. SINGER M
    Antibiotics for Sepsis - Does Each Hour Really Count? Or is it Incestuous Amplification?
    Am J Respir Crit Care Med. 2017 May 15. doi: 10.1164/rccm.201703-0621.
    PubMed     Text format    


  18. LIU V, Fielding-Singh V, Iwashyna TJ, Bhattacharya J, et al
    Reply to the Timing of Early Antibiotics and Hospital Mortality in Sepsis - Playing Devil's Advocate.
    Am J Respir Crit Care Med. 2017 May 9. doi: 10.1164/rccm.201704-0774.
    PubMed     Text format    


  19. CHERTOFF J, Ataya A
    The Timing of Early Antibiotics and Hospital Mortality in Sepsis - Playing Devil's Advocate.
    Am J Respir Crit Care Med. 2017 May 9. doi: 10.1164/rccm.201703-0657.
    PubMed     Text format    


    April 2017
  20. MIKACENIC C, Price BL, Harju-Baker S, O'Mahony DS, et al
    A Two Biomarker Model Predicts Mortality in the Critically Ill with Sepsis.
    Am J Respir Crit Care Med. 2017 Apr 18. doi: 10.1164/rccm.201611-2307.
    PubMed     Text format     Abstract available


  21. WATERER G, Restrepo MI
    Maladaptive Suppression of Bacterial Clearance in Early Sepsis. Setting the Scene for Failure.
    Am J Respir Crit Care Med. 2017;195:846-847.
    PubMed     Text format    


  22. HARRIS S
    Sepsis-3: Syndromes and Empiricism in the Age of Big Data.
    Am J Respir Crit Care Med. 2017;195:847-849.
    PubMed     Text format    


  23. CHURPEK MM, Snyder A, Han X, Sokol S, et al
    Quick Sepsis-related Organ Failure Assessment, Systemic Inflammatory Response Syndrome, and Early Warning Scores for Detecting Clinical Deterioration in Infected Patients outside the Intensive Care Unit.
    Am J Respir Crit Care Med. 2017;195:906-911.
    PubMed     Text format     Abstract available


    March 2017
  24. PARK SY, Shrestha S, Youn YJ, Kim JK, et al
    Autophagy Primes Neutrophils for Neutrophil Extracellular Trap Formation During Sepsis.
    Am J Respir Crit Care Med. 2017 Mar 30. doi: 10.1164/rccm.201603-0596.
    PubMed     Text format     Abstract available


  25. LIU VX, Fielding-Singh V, Greene JD, Baker JM, et al
    The Timing of Early Antibiotics and Hospital Mortality in Sepsis.
    Am J Respir Crit Care Med. 2017 Mar 27. doi: 10.1164/rccm.201609-1848.
    PubMed     Text format     Abstract available


    February 2017
  26. LEE S, Nakahira K, Dalli J, Siempos II, et al
    NLRP3 Inflammasome Deficiency Protects Against Microbial Sepsis via Increased Lipoxin B4 Synthesis.
    Am J Respir Crit Care Med. 2017 Feb 28. doi: 10.1164/rccm.201604-0892.
    PubMed     Text format     Abstract available


    January 2017
  27. VAN VUGHT LA, Wiewel MA, Hoogendijk AJ, Frencken JF, et al
    The Host Response in Sepsis Patients Developing Intensive Care Unit-acquired Secondary Infections.
    Am J Respir Crit Care Med. 2017 Jan 20. doi: 10.1164/rccm.201606-1225.
    PubMed     Text format     Abstract available


  28. WALKEY AJ, McManus D
    When Rhythm Changes Cause the Blues: New-Onset Atrial Fibrillation during Sepsis.
    Am J Respir Crit Care Med. 2017;195:152-154.
    PubMed     Text format    


  29. GEOGHEGAN S, Erviti A, Caballero MT, Vallone F, et al
    Mortality due to Respiratory Syncytial Virus. Burden and Risk Factors.
    Am J Respir Crit Care Med. 2017;195:96-103.
    PubMed     Text format     Abstract available


    December 2016
  30. BURNHAM KL, Davenport EE, Radhakrishnan J, Humburg P, et al
    Shared and Distinct Aspects of the Sepsis Transcriptomic Response to Fecal Peritonitis and Pneumonia.
    Am J Respir Crit Care Med. 2016 Dec 30. doi: 10.1164/rccm.201608-1685.
    PubMed     Text format     Abstract available


    November 2016
  31. ZHANG H, Li Y, van der Poll T
    Immune Modulation in Sepsis: Is There a Place for Progranulin?
    Am J Respir Crit Care Med. 2016;194:1179-1180.
    PubMed     Text format    


    October 2016
  32. AMATULLAH H, Shan Y, Beauchamp BL, Gali PL, et al
    DJ-1/PARK7 Impairs Bacterial Clearance in Sepsis.
    Am J Respir Crit Care Med. 2016.
    PubMed     Text format     Abstract available


    September 2016
  33. SCHULTE K, Linkermann A
    Welcome to the Jungle: The Kidney during Sepsis.
    Am J Respir Crit Care Med. 2016;194:649-50.
    PubMed     Text format    


    July 2016
  34. KLEIN KLOUWENBERG PM, Frencken JF, Kuipers S, Ong DS, et al
    Incidence, Predictors and Outcomes of New-onset Atrial Fibrillation in Critically Ill Patients with Sepsis: a Cohort Study.
    Am J Respir Crit Care Med. 2016.
    PubMed     Text format     Abstract available


  35. OU SM, Shih CJ, Chen YT
    Reply: The Methodology of Assessing Long-Term Mortality and Cardiovascular Risks in Survivors of Sepsis.
    Am J Respir Crit Care Med. 2016;194:246.
    PubMed     Text format    


  36. HENRIKSEN DP, Damkier P, Davidsen JR, Laursen CB, et al
    The Methodology of Assessing Long-Term Mortality and Cardiovascular Risks in Survivors of Sepsis.
    Am J Respir Crit Care Med. 2016;194:245-6.
    PubMed     Text format    


  37. STOLK RF, van der Poll T, Angus DC, van der Hoeven JG, et al
    Potentially Inadvertent Immunomodulation: Norepinephrine Use in Sepsis.
    Am J Respir Crit Care Med. 2016.
    PubMed     Text format     Abstract available


    June 2016
  38. LEVY MM
    Clarifying Sepsis Management.
    Am J Respir Crit Care Med. 2016;193:1195-6.
    PubMed     Text format    


    May 2016
  39. PRESCOTT HC, Calfee CS, Thompson BT, Angus DC, et al
    Towards Smarter Lumping and Smarter Splitting: Rethinking Strategies for Sepsis and ARDS Clinical Trial Design.
    Am J Respir Crit Care Med. 2016.
    PubMed     Text format     Abstract available


  40. PATEL J, Taneja A
    Tempering Sepsis-induced Hyperbilirubinemia: Implications for Short- and Long-Term Outcomes.
    Am J Respir Crit Care Med. 2016;193:1183.
    PubMed     Text format    


  41. BARBASH IJ, Kahn JM, Thompson BT
    Medicare's Sepsis Reporting Program: Two Steps Forward, One Step Back.
    Am J Respir Crit Care Med. 2016.
    PubMed     Text format    


  42. CALFEE CS
    Precision Medicine: An Opportunity to Improve Outcomes of Patients With Sepsis.
    Am J Respir Crit Care Med. 2016.
    PubMed     Text format    


  43. CORTES-PUCH I, Hartog CS
    Change is Not Necessarily Progress: Revision of the Sepsis Definition Should Be Based on New Scientific Insights.
    Am J Respir Crit Care Med. 2016.
    PubMed     Text format    


  44. ANGUS DC
    Defining Sepsis: A Case of Bounded Rationality and Fuzzy Thinking?
    Am J Respir Crit Care Med. 2016.
    PubMed     Text format    


  45. SONG Z, Zhang X, Zhang L, Xu F, et al
    Progranulin Plays a Central Role in Host Defense During Sepsis by Promoting Macrophage Recruitment.
    Am J Respir Crit Care Med. 2016.
    PubMed     Text format     Abstract available


    March 2016
  46. ROBERTS JA, Abdul-Aziz MH, Davis JS, Dulhunty JM, et al
    Continuous versus Intermittent Beta-lactam Infusion in Severe Sepsis: A Meta-analysis of Individual Patient Data From Randomized Trials.
    Am J Respir Crit Care Med. 2016.
    PubMed     Text format     Abstract available


    February 2016
  47. FINFER S, Machado FR
    The Global Epidemiology of Sepsis. Does It Matter That We Know So Little?
    Am J Respir Crit Care Med. 2016;193:228-30.
    PubMed     Text format    


  48. NESSELER N, Launey Y, Aninat C, White J, et al
    Liver Dysfunction Is Associated with Long-Term Mortality in Septic Shock.
    Am J Respir Crit Care Med. 2016;193:335-7.
    PubMed     Text format    


  49. HOSTE EA, De Loor J, Forni LG
    Treating Acute Kidney Injury. One Less Weapon in the Armamentarium?
    Am J Respir Crit Care Med. 2016;193:232-3.
    PubMed     Text format    


  50. KELLUM JA, Chawla LS, Keener C, Singbartl K, et al
    The Effects of Alternative Resuscitation Strategies on Acute Kidney Injury in Patients with Septic Shock.
    Am J Respir Crit Care Med. 2016;193:281-7.
    PubMed     Text format     Abstract available


    January 2016
  51. OU SM, Chu H, Chao PW, Lee YJ, et al
    Long-term Mortality and Major Adverse Cardiovascular Events in Sepsis Survivors: A Nationwide Population-based Study.
    Am J Respir Crit Care Med. 2016.
    PubMed     Text format     Abstract available



  52. Erratum: Global Epidemiology of Pediatric Severe Sepsis: The Sepsis Prevalence, Outcomes, and Therapies Study.
    Am J Respir Crit Care Med. 2016;193:223-4.
    PubMed     Text format    


  53. SNYDER LD, Chan C, Kwon D, Yi JS, et al
    Polyfunctional T-Cell Signatures to Predict Protection from Cytomegalovirus after Lung Transplantation.
    Am J Respir Crit Care Med. 2016;193:78-85.
    PubMed     Text format     Abstract available


    December 2015
  54. LIU VX, Morehouse JW, Marelich GP, Soule J, et al
    Multicenter Implementation of a Treatment Bundle for Sepsis Patients with Intermediate Lactate Values.
    Am J Respir Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  55. CHASTRE J, Luyt CE
    Continuous beta-Lactam Infusion to Optimize Antibiotic Use for Severe Sepsis. A Knife Cutting Water?
    Am J Respir Crit Care Med. 2015;192:1266-8.
    PubMed     Text format    


    October 2015
  56. SMYTH MA, Daniels R, Perkins GD
    Identification of Sepsis among Ward Patients.
    Am J Respir Crit Care Med. 2015;192:910-911.
    PubMed     Text format    


  57. KELLUM JA
    Are Outcomes from Severe Acute Kidney Injury Really Improving?
    Am J Respir Crit Care Med. 2015;192:909-10.
    PubMed     Text format    


  58. CHURPEK MM, Zadravecz FJ, Winslow C, Howell MD, et al
    Incidence and Prognostic Value of the Systemic Inflammatory Response Syndrome and Organ Dysfunctions in Ward Patients.
    Am J Respir Crit Care Med. 2015;192:958-64.
    PubMed     Text format     Abstract available


    September 2015
  59. FLEISCHMANN C, Scherag A, Adhikari NK, Hartog CS, et al
    Assessment of Global Incidence and Mortality of Hospital-treated Sepsis - Current Estimates and Limitations.
    Am J Respir Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  60. KAVANAGH BP, Nurok M
    Standardized Intensive Care - Protocol Misalignment and Impact Misattribution.
    Am J Respir Crit Care Med. 2015.
    PubMed     Text format     Abstract available


    July 2015
  61. DULHUNTY JM, Roberts JA, Davis JS, Webb SA, et al
    A Multicenter Randomized Trial of Continuous versus Intermittent beta-Lactam Infusion in Severe Sepsis.
    Am J Respir Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  62. SHIH CJ, Ou SM, Chen YT
    Reply: Renal Replacement Therapy in Sepsis.
    Am J Respir Crit Care Med. 2015;192:263.
    PubMed     Text format    


  63. SHEN HN
    Renal Replacement Therapy in Sepsis.
    Am J Respir Crit Care Med. 2015;192:263.
    PubMed     Text format    


    June 2015
  64. SAKHUJA A, Kumar G, Gupta S, Mittal T, et al
    Acute Kidney Injury Requiring Dialysis in Severe Sepsis.
    Am J Respir Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  65. SCHORTGEN F, Asfar P
    Update in sepsis and acute kidney injury 2014.
    Am J Respir Crit Care Med. 2015;191:1226-31.
    PubMed     Text format     Abstract available


    May 2015
  66. PRESCOTT HC, Dickson RP, Rogers MA, Langa KM, et al
    Hospitalization Type Predicts Risk of Subsequent Severe Sepsis.
    Am J Respir Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  67. SASIETA HC, Foley F, Batzlaff CM
    Chlorhexidine Bathing Impact on Infections, Effect of Etomidate on Sepsis Mortality, and Evaluation of Ventilator-associated Conditions.
    Am J Respir Crit Care Med. 2015;191:1197-9.
    PubMed     Text format    


  68. MARSHALL JC
    Understanding the global burden of pediatric sepsis.
    Am J Respir Crit Care Med. 2015;191:1096-8.
    PubMed     Text format    


    April 2015
  69. SHEHABI Y, Rachakonda KS, Bailey MJ, Peake S, et al
    Reply: No Significant Reduction in Antibiotic Treatment Using a Procalcitonin Algorithm with Low Cutoff Value in the Intensive Care Unit?
    Am J Respir Crit Care Med. 2015;191:859-860.
    PubMed     Text format    


  70. KLOOSTERBOER SM, van Zanten AR
    No Significant Reduction in Antibiotic Treatment Using a Procalcitonin Algorithm with Low Cutoff Value in the Intensive Care Unit?
    Am J Respir Crit Care Med. 2015;191:858-859.
    PubMed     Text format    


    March 2015
  71. CILLONIZ C, Albert RK, Liapikou A, Gabarrus A, et al
    The Effect of Macrolide-Resistance on the Presentation and Outcome of Patients Hospitalized for Streptococcus pneumoniae Pneumonia.
    Am J Respir Crit Care Med. 2015.
    PubMed     Text format     Abstract available


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