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Articles published in Crit Care Med

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Single Articles


    June 2017
  1. LEISMAN DE, Sethna CB
    Renin-Angiotensin-Aldosterone System Blockade Use in Sepsis Patients: Did It Impact Renal Outcomes?
    Crit Care Med. 2017;45:e624.
    PubMed     Text format    


  2. GAINES S, Alverdy JC
    Fecal Micobiota Transplantation to Treat Sepsis of Unclear Etiology.
    Crit Care Med. 2017;45:1106-1107.
    PubMed     Text format    


  3. FRAIMOW HS
    Safe at First, But Not Reaching Second: Implications of Delayed Second Doses of Antimicrobials in Patients Presenting to Emergency Departments With Sepsis.
    Crit Care Med. 2017;45:1097-1098.
    PubMed     Text format    


    May 2017
  4. DEUTSCHMAN CS
    "Defining" Sepsis: Moving Toward Measuring the "Dysregulated Host Response".
    Crit Care Med. 2017;45:927-930.
    PubMed     Text format    


  5. MARIK PE
    Glucocorticosteroids as Adjunctive Therapy for Acute Respiratory Distress Syndrome and Sepsis? Yes, But Not as Monotherapy.
    Crit Care Med. 2017;45:910-911.
    PubMed     Text format    


  6. LEVY MM
    Antibiotics in Sepsis: The New Frontier.
    Crit Care Med. 2017;45:907-908.
    PubMed     Text format    


  7. JUNG B, Mahul M, Breilh D, Legeron R, et al
    Repeated Piperacillin-Tazobactam Plasma Concentration Measurements in Severely Obese Versus Nonobese Critically Ill Septic Patients and the Risk of Under- and Overdosing.
    Crit Care Med. 2017;45:e470-e478.
    PubMed     Text format     Abstract available


  8. BERGAMIN FS, Almeida JP, Landoni G, Galas FRBG, et al
    Liberal Versus Restrictive Transfusion Strategy in Critically Ill Oncologic Patients: The Transfusion Requirements in Critically Ill Oncologic Patients Randomized Controlled Trial.
    Crit Care Med. 2017;45:766-773.
    PubMed     Text format     Abstract available


  9. DREWRY AM, Ablordeppey EA, Murray ET, Stoll CRT, et al
    Antipyretic Therapy in Critically Ill Septic Patients: A Systematic Review and Meta-Analysis.
    Crit Care Med. 2017;45:806-813.
    PubMed     Text format     Abstract available


    April 2017
  10. NORMAN BC, Cooke CR, Ely EW, Graves JA, et al
    Sepsis-Associated 30-Day Risk-Standardized Readmissions: Analysis of a Nationwide Medicare Sample.
    Crit Care Med. 2017 Apr 29. doi: 10.1097/CCM.0000000000002476.
    PubMed     Text format     Abstract available


  11. CHANG T, Tu YK, Lee CT, Chao A, et al
    Effects of Polymyxin B Hemoperfusion on Mortality in Patients With Severe Sepsis and Septic Shock: A Systemic Review, Meta-Analysis Update, and Disease Severity Subgroup Meta-Analysis.
    Crit Care Med. 2017 Apr 25. doi: 10.1097/CCM.0000000000002362.
    PubMed     Text format     Abstract available


  12. JIA P, Wu X, Dai Y, Teng J, et al
    MicroRNA-21 Is Required for Local and Remote Ischemic Preconditioning in Multiple Organ Protection Against Sepsis.
    Crit Care Med. 2017 Apr 21. doi: 10.1097/CCM.0000000000002363.
    PubMed     Text format     Abstract available


  13. EMRATH ET, Fortenberry JD, Travers C, McCracken CE, et al
    Resuscitation With Balanced Fluids Is Associated With Improved Survival in Pediatric Severe Sepsis.
    Crit Care Med. 2017 Apr 21. doi: 10.1097/CCM.0000000000002365.
    PubMed     Text format     Abstract available


  14. ARULKUMARAN N, Sixma ML, Jentho E, Ceravola E, et al
    Sequential Analysis of a Panel of Biomarkers and Pathologic Findings in a Resuscitated Rat Model of Sepsis and Recovery.
    Crit Care Med. 2017 Apr 20. doi: 10.1097/CCM.0000000000002381.
    PubMed     Text format     Abstract available


  15. ZHOU J, Tian H, Du X, Xi X, et al
    Population-Based Epidemiology of Sepsis in a Subdistrict of Beijing.
    Crit Care Med. 2017 Apr 18. doi: 10.1097/CCM.0000000000002414.
    PubMed     Text format     Abstract available


  16. PINTO BB, Dyson A, Umbrello M, Carre JE, et al
    Improved Survival in a Long-Term Rat Model of Sepsis Is Associated With Reduced Mitochondrial Calcium Uptake Despite Increased Energetic Demand.
    Crit Care Med. 2017 Apr 13. doi: 10.1097/CCM.0000000000002448.
    PubMed     Text format     Abstract available


  17. SCICLUNA BP, van der Poll T
    Turning a New Page in Sepsis Molecular Diagnostics Necessitates Context-Specific Biomarkers.
    Crit Care Med. 2017;45:e457.
    PubMed     Text format    


  18. WALLEY KR
    New Approaches to Modifying Inotropy in Sepsis-Induced Myocardial Dysfunction.
    Crit Care Med. 2017;45:754-756.
    PubMed     Text format    


  19. SIMPSON SQ
    Surviving Transfer for Sepsis: Size Matters-Or Does It?
    Crit Care Med. 2017;45:749-750.
    PubMed     Text format    


  20. LAUPLAND KB, Niven DJ
    The Normal Abnormal Vital Sign of Sepsis.
    Crit Care Med. 2017;45:747-748.
    PubMed     Text format    


  21. DEUTSCHMAN CS
    Sepsis-3: Of Love and Bliss.
    Crit Care Med. 2017;45:739-740.
    PubMed     Text format    


    March 2017
  22. FAWZY A, Walkey AJ
    Association Between Hospital Case Volume of Sepsis, Adherence to Evidence-Based Processes of Care and Patient Outcomes.
    Crit Care Med. 2017 Mar 27. doi: 10.1097/CCM.0000000000002409.
    PubMed     Text format     Abstract available


  23. LEISMAN D, Huang V, Zhou Q, Gribben J, et al
    Delayed Second Dose Antibiotics for Patients Admitted From the Emergency Department With Sepsis: Prevalence, Risk Factors, and Outcomes.
    Crit Care Med. 2017 Mar 21. doi: 10.1097/CCM.0000000000002377.
    PubMed     Text format     Abstract available


  24. SHANKAR-HARI M, Fear D, Lavender P, Mare T, et al
    Activation-Associated Accelerated Apoptosis of Memory B Cells in Critically Ill Patients With Sepsis.
    Crit Care Med. 2017 Mar 14. doi: 10.1097/CCM.0000000000002380.
    PubMed     Text format     Abstract available


  25. MOSS TJ, Calland JF, Enfield KB, Gomez-Manjarres DC, et al
    New-Onset Atrial Fibrillation in the Critically Ill.
    Crit Care Med. 2017 Mar 14. doi: 10.1097/CCM.0000000000002325.
    PubMed     Text format     Abstract available


  26. MCKOWN AC, McGuinn EM, Ware LB, Wang L, et al
    Preadmission Oral Corticosteroids Are Associated With Reduced Risk of Acute Respiratory Distress Syndrome in Critically Ill Adults With Sepsis.
    Crit Care Med. 2017 Mar 2. doi: 10.1097/CCM.0000000000002286.
    PubMed     Text format     Abstract available


  27. SCHUETZ P, Birkhahn R, Sherwin R, Jones AE, et al
    Serial Procalcitonin Predicts Mortality in Severe Sepsis Patients: Results From the Multicenter Procalcitonin MOnitoring SEpsis (MOSES) Study.
    Crit Care Med. 2017 Mar 2. doi: 10.1097/CCM.0000000000002321.
    PubMed     Text format     Abstract available


  28. FRENCKEN JF, van Vught LA, Peelen LM, Ong DS, et al
    An Unbalanced Inflammatory Cytokine Response Is Not Associated With Mortality Following Sepsis: A Prospective Cohort Study.
    Crit Care Med. 2017 Mar 2. doi: 10.1097/CCM.0000000000002292.
    PubMed     Text format     Abstract available


  29. PEPPER DJ
    Adipose Tissue Measurements in Patients With Sepsis.
    Crit Care Med. 2017;45:e331.
    PubMed     Text format    


  30. KUHN SO, Meissner K, Rehberg S
    Fluid Resuscitation in Sepsis: "Get the Balance Right".
    Crit Care Med. 2017;45:555-556.
    PubMed     Text format    


  31. MOROWITZ MJ, Di Caro V, Pang D, Cummings J, et al
    Dietary Supplementation With Nonfermentable Fiber Alters the Gut Microbiota and Confers Protection in Murine Models of Sepsis.
    Crit Care Med. 2017 Mar 1. doi: 10.1097/CCM.0000000000002291.
    PubMed     Text format     Abstract available


    February 2017
  32. HOOGENDIJK AJ, Garcia-Laorden MI, van Vught LA, Wiewel MA, et al
    Sepsis Patients Display a Reduced Capacity to Activate Nuclear Factor-kappaB in Multiple Cell Types.
    Crit Care Med. 2017 Feb 24. doi: 10.1097/CCM.0000000000002294.
    PubMed     Text format     Abstract available


  33. SEYMOUR CW, Kahn JM, Martin-Gill C, Callaway CW, et al
    Delays From First Medical Contact to Antibiotic Administration for Sepsis.
    Crit Care Med. 2017 Feb 23. doi: 10.1097/CCM.0000000000002264.
    PubMed     Text format     Abstract available


  34. WHILES BB, Deis AS, Simpson SQ
    Increased Time to Initial Antimicrobial Administration Is Associated With Progression to Septic Shock in Severe Sepsis Patients.
    Crit Care Med. 2017 Feb 6. doi: 10.1097/CCM.0000000000002262.
    PubMed     Text format     Abstract available


  35. BRENT AJ
    Meta-Analysis of Time to Antimicrobial Therapy in Sepsis: Confounding as Well as Bias.
    Crit Care Med. 2017;45:e242-e243.
    PubMed     Text format    


  36. BRIASSOULIS G, Ilia S
    Vitamin D Deficiency in Sepsis: "Body Humors" Imbalance or Sepsis "Epiphenomenon"?
    Crit Care Med. 2017;45:376-377.
    PubMed     Text format    


  37. BHARDWAJ A, Mikkelsen ME
    Sepsis Quality Improvement Initiatives: Prepare for the Marathon, Not the Sprint.
    Crit Care Med. 2017;45:374-375.
    PubMed     Text format    


  38. ALVERDY JC, Krezalek MA
    Collapse of the Microbiome, Emergence of the Pathobiome, and the Immunopathology of Sepsis.
    Crit Care Med. 2017;45:337-347.
    PubMed     Text format     Abstract available


  39. VON BAHR V, Hultman J, Eksborg S, Frenckner B, et al
    Long-Term Survival in Adults Treated With Extracorporeal Membrane Oxygenation for Respiratory Failure and Sepsis.
    Crit Care Med. 2017;45:164-170.
    PubMed     Text format     Abstract available


  40. OFOMA UR, Dahdah J, Kethireddy S, Maeng D, et al
    Case Volume-Outcomes Associations Among Patients With Severe Sepsis Who Underwent Interhospital Transfer.
    Crit Care Med. 2017 Feb 1. doi: 10.1097/CCM.0000000000002254.
    PubMed     Text format     Abstract available


    January 2017
  41. SUNDEN-CULLBERG J, Rylance R, Svefors J, Norrby-Teglund A, et al
    Fever in the Emergency Department Predicts Survival of Patients With Severe Sepsis and Septic Shock Admitted to the ICU.
    Crit Care Med. 2017 Jan 30. doi: 10.1097/CCM.0000000000002249.
    PubMed     Text format     Abstract available


  42. DELLINGER RP, Schorr CA, Levy MM
    A Users' Guide to the 2016 Surviving Sepsis Guidelines.
    Crit Care Med. 2017 Jan 17. doi: 10.1097/CCM.0000000000002257.
    PubMed     Text format    


  43. COZ YATACO A, Jaehne AK, Rivers EP
    Protocolized Early Sepsis Care Is Not Only Helpful for Patients: It Prevents Medical Errors.
    Crit Care Med. 2017 Jan 17. doi: 10.1097/CCM.0000000000002237.
    PubMed     Text format    


  44. RHODES A, Evans LE, Alhazzani W, Levy MM, et al
    Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.
    Crit Care Med. 2017 Jan 17. doi: 10.1097/CCM.0000000000002255.
    PubMed     Text format     Abstract available


  45. WIEWEL MA, van Vught LA, Scicluna BP, Hoogendijk AJ, et al
    Prior Use of Calcium Channel Blockers Is Associated With Decreased Mortality in Critically Ill Patients With Sepsis; a Prospective Observational Study.
    Crit Care Med. 2017 Jan 10. doi: 10.1097/CCM.0000000000002236.
    PubMed     Text format     Abstract available


  46. MATKOVICH SJ, Al Khiami B, Efimov IR, Evans S, et al
    Widespread Down-Regulation of Cardiac Mitochondrial and Sarcomeric Genes in Patients With Sepsis.
    Crit Care Med. 2017 Jan 6. doi: 10.1097/CCM.0000000000002207.
    PubMed     Text format     Abstract available


  47. KALIL AC, Johnson DW, Lisco SJ, Sun J, et al
    Early Goal-Directed Therapy for Sepsis: A Novel Solution for Discordant Survival Outcomes in Clinical Trials.
    Crit Care Med. 2017 Jan 6. doi: 10.1097/CCM.0000000000002235.
    PubMed     Text format     Abstract available


  48. CROUSER ED, Hotchkiss RS
    Desperate Times Call for Desperate Measures: Self-Cannibalism Is Protective During Sepsis.
    Crit Care Med. 2017;45:145-147.
    PubMed     Text format    


  49. RIE M
    Rural Sepsis Mortality: Patient Emergency Care Preference Impacts Resuscitation Outcome Value.
    Crit Care Med. 2017;45:138-139.
    PubMed     Text format    


  50. OPAL SM
    Source Control in Sepsis Urgent or Not So Fast?
    Crit Care Med. 2017;45:130-132.
    PubMed     Text format    


  51. MIRA JC, Moldawer LL
    Sepsis Diagnostics: From Discovery to Application.
    Crit Care Med. 2017;45:129-130.
    PubMed     Text format    


    December 2016
  52. LEISMAN DE, Doerfler ME, Ward MF, Masick KD, et al
    Survival Benefit and Cost Savings From Compliance With a Simplified 3-Hour Sepsis Bundle in a Series of Prospective, Multisite, Observational Cohorts.
    Crit Care Med. 2016.
    PubMed     Text format     Abstract available


  53. SAKR Y, Rubatto Birri PN, Kotfis K, Nanchal R, et al
    Higher Fluid Balance Increases the Risk of Death From Sepsis: Results From a Large International Audit.
    Crit Care Med. 2016.
    PubMed     Text format     Abstract available


  54. KRISHNAN S, Shah K, Dhillon G, Presberg K, et al
    1995: FATAL PURPURA FULMINANS AND FULMINANT PSEUDOMONAL SEPSIS.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  55. SOLVERSON K, Doig C
    1990: A FATAL CASE OF OVERWHELMING PNEUMOCOCCAL SEPSIS IN A SPLENECTOMISED PATIENT.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  56. SHANBHAG A, Llanos Ulloa O, Meena N
    1988: PNEUMOCOCCAL SEPSIS IN ITP POST-SPLENECTOMY AND VACCINATION DUE TO COEXISTING CVID.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  57. LIU C, Crnkovic A, Dalfino J, Barlin J, et al
    1830: WHETHER TO PROCEED WITH DEEP BRAIN STIMULATOR BATTERY CHANGE IN A PATIENT WITH POTENTIAL SEPSIS.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  58. HITOSUGI-LEVESQUE M, Devendra G
    1780: A FATAL CASE OF VIBRIO VULNIFICUS SEPSIS WITH HEMORRHAGIC BULLAE.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  59. MEDEPALLI K, Benninger L, Lebeck-Lee C, Elwing J, et al
    1741: CHEMOTHERAPY: A THERAPEUTIC OPTION IN SEPSIS?
    Crit Care Med. 2016;44.
    PubMed     Text format    


  60. GUTIERREZ J, Andavolu R, Ursell P
    1650: MYOCARDIAL CALCIFICATION IN PEDIATRIC VIRAL SEPSIS.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  61. MALHOTRA I, Desoky H, Shenoy MA, Shankar S, et al
    1619: SEPSIS-INDUCED ISOLATED RIGHT VENTRICULAR STRESS CARDIOMYOPATHY MASQUERADING AS PULMONARY EMBOLISM.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  62. ROBERTSON J, Criss C, Hsieh L, Gish J, et al
    1500: STEROID USE FOR REFRACTORY HYPOTENSION IN CONGENITAL DIAPHRAGMATIC HERNIA INCREASES SEPSIS RISK.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  63. JUNE A, Bhutta A, Holloway A, Bagdure D, et al
    1493: OUTCOMES OF PATIENTS WITH SEPSIS RELATED TO STAPHALOCOCCUS AUREUS MANAGED WITH ECMO.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  64. KYO M, Ohshimo S, Kida Y, Shime N, et al
    1492: THE VALIDATION OF QSOFA CRITERIA FOR SEPSIS.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  65. SAITO N, Kawasaki A, Akizuki N, Namiki M, et al
    1491: ANTITHROMBIN III DEFICIENCY RELATES TO MORTALITY IN SEPSIS.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  66. BLAU S, Spector R
    1487: SEPSIS CARE IN NEW YORK STATE: SERVING TWO MASTERS.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  67. DICK-PEREZ R, Mohr N, Harland K, Ahmed A, et al
    1479: ED CHARGES PREDICT SEVERITY OF ILLNESS AND MORTALITY IN PATIENTS WITH SEVERE SEPSIS/SEPTIC SHOCK.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  68. EL QADDOUMI H, Roy A, Davis J, Katsikeris F, et al
    1478: PRESENTATION AND COURSE OF PRENATAL SEPSIS IN AN ACADEMIC MEDICAL CENTER.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  69. GRAHAM J, Krall B, Presente A, Saucier J, et al
    1477: SOFA SCORES IN PATIENTS TRIGGERING AN EMR-BASED SEPSIS ALERT.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  70. NAZER L, Abusara A, Hawari F
    1476: ASSESSING THE 3RD INTERNATIONAL CONSENSUS DEFINITION FOR SEPTIC SHOCK (SEPSIS-3) IN CANCER PATIENTS.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  71. DELUCA P, Ali S, Fryckberg A, Vyas N, et al
    1475: ASSESSMENT OF NONCOMPLIANCE WITH BUNDLE THERAPY FOR THE TREATMENT OF SEPSIS ON THE INPATIENT FLOOR.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  72. HARTKOPP B, Fletcher S, Ekengren F, Berg G, et al
    1473: TERTIARY HOSPITAL SEPSIS CHAMPION: EDUCATION REVEALS NEEDS AND INCREASES TRANSFERS.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  73. JIM F, Li J, Peng Z
    1472: ACTIVATION OF THE CHOLINERGIC ANTIINFLAMMATORY PATHWAY IMPROVES SEPSIS-INDUCED HYPERGLYCEMIA.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  74. JAIMES F, Castano P, Plaza M, Molina F, et al
    1470: ANTIBIOTICS PRESCRIPTION IS NOT ASSOCIATED WITH PROGNOSIS IN SEPSIS: A PROSPECTIVE COHORT STUDY.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  75. LIMA K, Caynak R, Lara F, Tran N, et al
    1469: LACTATE MONITORING FOR SEVERE SEPSIS AND SEPTIC SHOCK: ARE ALL LACTATE MEASUREMENTS THE SAME?
    Crit Care Med. 2016;44.
    PubMed     Text format    


  76. WEISS S, Balamuth F, Fitzgerald J, Hensley J, et al
    1468: EPIDEMIOLOGY OF DEATH FOLLOWING PEDIATRIC SEPSIS: WHEN, WHY, AND HOW SEPTIC KIDS DIE.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  77. FRENCKEN J, Donker D, Horn J, Van Der Poll T, et al
    1462: MYOCARDIAL INJURY DURING SEPSIS: INCIDENCE AND ASSOCIATION WITH MORTALITY.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  78. BREUER R, Hassinger A
    1461: THE PEDIATRIC PROVIDER EXPERIENCE WITH SEPSIS AND SEPTIC SHOCK (PRESS) STUDY.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  79. ZILBERBERG M, Shorr A, Micek S, Williams M, et al
    1460: EPIDEMIOLOGY AND OUTCOMES OF SEPSIS-ASSOCIATED COAGULOPATHY IN SEVERE SEPSIS AND SEPTIC SHOCK.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  80. TAKAUJI S, Hayakawa M, Ono K, Fujita S, et al
    1459: VENOARTERIAL EXTRACORPOREAL MEMBRANE OXYGENATION FOR SEVERE SEPSIS AND SEPTIC SHOCK IN 3,195 ADULTS.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  81. NOURIEL J, Millis S, Ottolini J, Wilburn J, et al
    1457: THE RELATIONSHIP BETWEEN BLOOD PRESSURE VARIABILITY AND LACTATE IN EARLY SEPSIS RESUSCITATION.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  82. GUIRGIS F, Sterling S, Smotherman C, Moore F, et al
    1456: A COMPARISON OF SOFA USING SPO2/FIO2 RATIO TO SOFA, SIRS, AND QSOFA FOR SEPSIS MORTALITY.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  83. YUNE H, Kim K, Jo YH, Kim J, et al
    1453: INFUSION OF METHYLENE BLUE IN SEVERE SEPSIS AND SEPTIC SHOCK: A RANDOMIZED CONTROLLED TRIAL.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  84. JAIMES F, Londono J, Nino C, Valencia M, et al
    1452: NO IMPROVEMENT WITH EGDT OR ANTIBIOTICS IN PATIENTS WITH SEPSIS: AN INSTRUMENTAL VARIABLE ANALYSIS.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  85. HARTOG C, Matt B, Kortgen A, Konig C, et al
    1446: WHAT MATTERS MOST TO SURVIVORS OF SEPSIS? DEVELOPMENT OF PATIENT-REPORTED QUALITY-OF-LIFE DOMAINS.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  86. SAKHUJA A, Kumar G, Vallabhajosyula S, Kashyap R, et al
    1445: WHO CAN BE CALLED "ELDERLY" FOR SEVERE SEPSIS MORTALITY?
    Crit Care Med. 2016;44.
    PubMed     Text format    


  87. LEVY E, Zinter M, Madden K, Randolph A, et al
    1444: MANNOSE-BINDING LECTIN AND PEDIATRIC SEPSIS SUSCEPTIBILITY: A SYSTEMATIC REVIEW AND META-ANALYSIS.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  88. HANDY B, Jones P, Ostlund R Jr, Schuetz P, et al
    1440: VALIDATION OF THE ELECSYS BRAHMS PROCALCITONIN ASSAY IN PATIENTS WITH SEVERE SEPSIS OR SEPTIC SHOCK.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  89. MILZMAN D, Paik M, Shuster K, Floyd R, et al
    1438: EARLY DETERMINATION OF OUTCOMES FOR SIRS VS QSOFA IN ED SEPSIS PATIENTS.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  90. WALKER J, Peters M, Nadel S, Pathan N, et al
    1436: THE ABILITY OF SEPSIS CRITERIA TO PREDICT SERIOUS BACTERIAL INFECTION IN CRITICALLY ILL CHILDREN.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  91. MORESCO B, Root K, Cuellar C, Harkins L, et al
    1435: EVALUATION OF EARLY MANAGEMENT OF SEPSIS AND COMPLIANCE WITH SEPSIS GUIDELINES.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  92. WISKAR K, Boyd J, Rush B
    1434: ASSOCIATION BETWEEN HOSPITAL CHARACTERISTICS AND MORTALITY IN SEPSIS.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  93. TAYLOR S, Gandy T, Karvestski C, Templin M, et al
    1428: INCIDENCE, PREDICTORS, AND ALTERNATE DIAGNOSES OF PATIENTS WITH FALSE-POSITIVE SEVERE SEPSIS.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  94. FERREIRA J, Adams C, Tucker C, Allen B, et al
    1427: EFFICACY OF NON-WEIGHT-BASED VASOPRESSOR DOSING IN CRITICALLY ILL PATIENTS WITH SEVERE SEPSIS.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  95. LEISMAN D, D'Amore J, Gribben J, Ward M, et al
    1426: BUNDLE COMPLIANCE EFFECT GREATER IN HEMODYNAMICALLY STABLE SEPSIS PATIENTS WITH INTERMEDIATE LACTATE.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  96. SPECTOR R, Blau S
    1425: SEPSIS MANAGEMENT: THE EFFECT OF PROTOCOL INITIATION ON PATIENT OUTCOME.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  97. PARK JR, Kim Y, Park T, Oh WY, et al
    1423: MICROCIRCULATORY ALTERATIONS IN HEMORRHAGIC SHOCK AND SEPSIS WITH OPTICAL COHERENCE TOMOGRAPHY.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  98. PEARSON D, Benson A, Blanset J, Lovett K, et al
    1422: COMMON REASONS CORE MEASURES ARE NOT MET IN PATIENTS WITH SEVERE SEPSIS AND SEPTIC SHOCK.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  99. PELTAN I, Mitchell K, Rudd K, Mann B, et al
    1421: PREHOSPITAL LEVEL OF CARE, PREHOSPITAL IV ACCESS, AND TIMING OF ANTIBIOTICS IN SEPSIS.
    Crit Care Med. 2016;44.
    PubMed     Text format    


  100. IBARRA F, Rowden A, Dzintars K, Lindsley J, et al
    1418: UTILITY OF A SEVERE SEPSIS ORDER SET IN A MEDICAL INTENSIVE CARE UNIT.
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  101. WOZNIAK J, Dargin J
    1416: THE EFFECT OF PROVIDING CLINICAL PERFORMANCE FEEDBACK ON COMPLIANCE WITH SEPSIS TREATMENT BUNDLES.
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  102. WOZNIAK J, Dargin J
    1415: THE EFFECT OF PROVIDING CLINICAL PERFORMANCE FEEDBACK ON COMPLIANCE WITH SEPSIS TREATMENT BUNDLES.
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  103. HUANG C, Daniels R, Lembo A, Heymann T, et al
    1413: MENTAL, PHYSIOLOGIC, AND FUNCTIONAL DISABILITIES IN POST-SEPSIS SYNDROME: AN INTERNATIONAL SURVEY.
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  104. NGUYEN T, Marini J, Lam F, Cohen D, et al
    1411: PORCINE MODEL OF STAPHYLOCOCCUS AUREUS SEPSIS-INDUCED DISSEMINATED INTRAVASCULAR COAGULATION.
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  105. STEGER A, Pedersen A, Shears E, Hurst L, et al
    1409: A NURSE-LED APPROACH TO IMPROVE EARLY SEPSIS CARE IN THE EMERGENCY DEPARTMENT.
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  106. SHAH T, Rech M, Sterk E
    1406: IMPACT OF THE EMERGENCY DEPARTMENT SEPSIS SCREENING TOOL ON OUTCOMES IN PATIENTS WITH SEPSIS.
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  107. SAKHUJA A, Kumar G, Vallabhajosyula S, Kashani K, et al
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  108. TAYLOR S, Roohollahi A, Karvetski C, Templin M, et al
    1403: DOES CIRRHOSIS AFFECT THE PROGNOSTIC UTILITY OF LACTATE FOR SEVERE SEPSIS?
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  109. ATEELI H, Jaffer F, Goel K, Low SW, et al
    1402: CURB-65 SCORE CORRELATES WITH ICU ADMISSION AND IN-HOSPITAL MORTALITY IN PATIENTS WITH SEPSIS.
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  110. CUSTER J, Bhutta A, Bagdure D, Holloway A, et al
    1399: OUTCOMES OF PEDIATRIC PATIENTS WITH SEPSIS MANAGED ON EXTRACORPOREAL MEMBRANE OXYGENATION.
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  111. HOSHINO K, Kawano Y, Maruyama J, Mizunuma M, et al
    1398: PLASMINOGEN ACTIVATOR INHIBITOR-1 IS THE MOST PREDICTIVE MARKER OF MORTALITY IN SEPSIS.
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  112. HUANG C, Daniels R, Lembo A, Heymann T, et al
    1397: SEPSIS SURVIVORS' SATISFACTION WITH SUPPORT SERVICES DURING AND AFTER THEIR HOSPITALIZATION.
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  113. LEISMAN D, Huang V, Zhou Q, Gribben J, et al
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  114. TANNEHILL D, O'Brien J, Kasal J, Subramanian S, et al
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  115. MCHUGH W, McDonough K, Carlton E, Kidwell K, et al
    1394: PERSONALIZED IMMUNOMODULATION IN HIGH-RISK SEPSIS PATIENTS IN A PEDIATRIC CRITICAL CARE UNIT.
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  116. MAHAPATRA S, Ying L, Steinman L, Cornfield D, et al
    1393: AN AMYLOIDOGENIC HEXAPEPTIDE, AMYLIN, ATTENUATES INFLAMMATION AND ACUTE LUNG INJURY IN MURINE SEPSIS.
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  117. FUKUDA S, Randolph A, Ihara K, Cox R, et al
    1390: PEROXYNITRITE DECOMPOSITION CATALYST REDUCES NOREPINEPHRINE REQUIREMENT DURING SEPSIS IN OVINE MODEL.
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  118. MOORE C, Ainsworth J, Wang Y, Barnes L, et al
    1389: OPTIMIZED PREDICTIVE MONITORING OF NON-INTENSIVE CARE UNIT PATIENTS AT RISK FOR SEPSIS.
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  119. RUSH B, Wiskar K, Boyd J
    1388: ASSOCIATION OF WEEKEND ADMISSION WITH SEPSIS MORTALITY IN THE UNITED STATES.
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  120. KWAK S
    1387: FLECAINIDE ATTENUATES SEPSIS-INDUCED ACUTE LUNG INJURY BY CONTROLLING INFLAMMATORY RESPONSE.
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  121. TRAN N, Lima K, Caynak R, Scobino C, et al
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  122. STILL M, Carpenter D, Holder C, Murphy D, et al
    1384: SUCCESS WITH IMPLEMENTATION OF A SYSTEM-BASED SEPSIS MANAGEMENT PROGRAM.
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  123. RINATO K, Pretto-Sparkuhl A, Mauch H, Viti L, et al
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  124. AAKRE C, Kitson J, Herasevich V
    1380: TIME-MOTION ANALYSIS AND ECONOMIC IMPACT OF SOFA SCORE INTEGRATION INTO THE NEW SEPSIS-3 DEFINITION.
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  125. LEWIS A, Yuan D, Zhang X, Collage R, et al
    1379: BLUE LIGHT THERAPY MODULATES THE SYSTEMIC RESPONSE TO SEPSIS IN MICE AND HUMANS.
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  126. SATO R, Kuriyama A, Takada T, Nasu M, et al
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  127. GELVEZ J, Olarte JL, Williams L, Darnell C, et al
    1376: THE EFFECT OF EMERGENCY ROOM FLUID RESUSCITATION ON PATIENTS WITH SEVERE SEPSIS AND SEPTIC SHOCK.
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  128. HUDCOVA J, Poutsiaka D, Khan M, Waqas A, et al
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  129. LIMA L, McCracken C, Fortenberry J, Hebbar K, et al
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  130. MIKACENIC C, Price B, Harju-Baker S, Katz R, et al
    1372: DEVELOPMENT OF A ROBUST BIOMARKER PREDICTIVE MODEL FOR DEATH IN ICU PATIENTS WITH SIRS AND SEPSIS.
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  131. SCOTT H, Brou L, Deakyne S, Bajaj L, et al
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  132. TAYLOR B, Gunn E, Templin M, Karvestski C, et al
    1370: VOLUME ADMINISTRATION AND OUTCOMES IN OBESE PATIENTS WITH SEPSIS IN THE ERA OF PROTOCOLIZED CARE.
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  133. LI X, Guo L, Yuan Y, Zhan CG, et al
    1368: SYNTHETIC HDL AS AN EFFECTIVE THERAPY FOR SEPSIS.
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  134. CHUNG KS, Kim CY, Lee SH, Kim SK, et al
    1366: CLINICAL IMPLICATIONS OF THE PLASMA EPHA2 RECEPTOR LEVEL IN PATIENTS WITH SEPSIS.
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  135. TANNEHILL D, Sharpe B, Miller M, Saifo A, et al
    1365: SEPSIS-3 APPLIED TO A HISTORICAL COHORT OF SEVERE SEPSIS PATIENTS TREATED OUTSIDE THE ICU.
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  136. GASPERINO J, Gabriel-Jocson E, Perez E, Levy R, et al
    1364: COMPARISON OF THE QSOFA SCORE AND SIRS CRITERIA IN PATIENTS WITH KNOWN OR SUSPECTED SEPSIS.
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  137. ZHAI X, Jiang L, Yang Z, Yu T, et al
    1363: EFFECT OF ULINASTATIN ON MICROCIRCULATION DURING SEPSIS IN A RAT CECAL LIGATION AND PUNCTURE MODEL.
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  138. VALLABHAJOSYULA S, Jentzer J, Geske J, Kashani K, et al
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  139. WALSH M, Hobbs B, Giancarelli A, Bhullar I, et al
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  140. TAYLOR B, Alexander M, Karvestski C, Templin M, et al
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  141. LANTRY J, April M
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    1352: IMPACT OF MITOCHONDRIAL ROS SCAVENGERS ON CARDIAC MECHANICS IN A MURINE MODEL OF SEPSIS.
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  143. KAWANO Y, Hoshino K, Irie Y, Izutani Y, et al
    1347: USEFULNESS OF SEPSIS BIOMARKERS ACCORDING TO THE NEW DEFINITIONS OF SEPSIS.
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  146. TYLER P, Celi LA, Rush B
    1342: INTERHOSPITAL TRANSFER OF PATIENTS WITH SEPSIS ACROSS THE UNITED STATES.
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  147. MARIK P, Bittner E, Hansell D, Sahatjian J, et al
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  180. KEMPKER JA, Martin GS
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  181. TOWNSEND SR
    Collaborating for Success in Sepsis Quality Improvement.
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  199. AARVOLD AB, Ryan HM, Magee LA, von Dadelszen P, et al
    Multiple Organ Dysfunction Score Is Superior to the Obstetric-Specific Sepsis in Obstetrics Score in Predicting Mortality in Septic Obstetric Patients.
    Crit Care Med. 2016.
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  200. OAMI T, Watanabe E, Hatano M, Sunahara S, et al
    Suppression of T Cell Autophagy Results in Decreased Viability and Function of T Cells Through Accelerated Apoptosis in a Murine Sepsis Model.
    Crit Care Med. 2016.
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  201. MOHR NM, Harland KK, Shane DM, Ahmed A, et al
    Rural Patients With Severe Sepsis or Septic Shock who Bypass Rural Hospitals Have Increased Mortality: An Instrumental Variables Approach.
    Crit Care Med. 2016.
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  202. MARTINEZ ML, Ferrer R, Torrents E, Guillamat-Prats R, et al
    Impact of Source Control in Patients With Severe Sepsis and Septic Shock.
    Crit Care Med. 2016.
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  203. BUNGER R, Mallet RT
    Metabolomics and Receiver Operating Characteristic Analysis: A Promising Approach for Sepsis Diagnosis.
    Crit Care Med. 2016;44:1784-5.
    PubMed     Text format    


    August 2016
  204. LI X, Kondo Y, Bao Y, Staudenmaier L, et al
    Systemic Adenosine Triphosphate Impairs Neutrophil Chemotaxis and Host Defense in Sepsis.
    Crit Care Med. 2016.
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  205. TSOYI K, Hall SR, Dalli J, Colas RA, et al
    Carbon Monoxide Improves Efficacy of Mesenchymal Stromal Cells During Sepsis by Production of Specialized Proresolving Lipid Mediators.
    Crit Care Med. 2016.
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  206. FITZGERALD JC, Basu RK, Akcan-Arikan A, Izquierdo LM, et al
    Acute Kidney Injury in Pediatric Severe Sepsis: An Independent Risk Factor for Death and New Disability.
    Crit Care Med. 2016.
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  207. WONG HR, Cvijanovich NZ, Anas N, Allen GL, et al
    Pediatric Sepsis Biomarker Risk Model-II: Redefining the Pediatric Sepsis Biomarker Risk Model With Septic Shock Phenotype.
    Crit Care Med. 2016.
    PubMed     Text format     Abstract available


  208. DELANEY A
    Protocolized Sepsis Care Is Not Helpful for Patients.
    Crit Care Med. 2016.
    PubMed     Text format    


  209. SAVAS G, Kalay N
    beta-Blocker Therapy Could Inflate the Diagnosis of Severe Sepsis.
    Crit Care Med. 2016;44:e765-6.
    PubMed     Text format    


  210. HAYES AJ, Mole DJ
    Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase Inhibition During Sepsis Dampens the Early Systemic Inflammatory Response.
    Crit Care Med. 2016;44:1628-9.
    PubMed     Text format    


  211. CROUSER ED
    Sepsis-Induced Endoplasmic Reticulum Stress: A Matter of Life and Death?
    Crit Care Med. 2016;44:1626-7.
    PubMed     Text format    


  212. HALBACH J, Bickler S, De Maio A
    The Molecular Complexity of Sepsis: Expression of Peroxisome Proliferator-Activated Receptor-alpha, the Tip of the Iceberg?
    Crit Care Med. 2016;44:1617-8.
    PubMed     Text format    


  213. ANDERSON-SHAW L
    Surviving Severe Sepsis: Is That Enough?
    Crit Care Med. 2016;44:1603-4.
    PubMed     Text format    


  214. MARSHALL JC
    Sepsis-3: What is the Meaning of a Definition?
    Crit Care Med. 2016;44:1459-60.
    PubMed     Text format    


    July 2016
  215. THOMPSON MP, Reeves MJ, Bogan BL, DiGiovine B, et al
    Protocol-Based Resuscitation Bundle to Improve Outcomes in Septic Shock Patients: Evaluation of the Michigan Health and Hospital Association Keystone Sepsis Collaborative.
    Crit Care Med. 2016.
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  216. LINDNER HA, Balaban U, Sturm T, Wei C, et al
    An Algorithm for Systemic Inflammatory Response Syndrome Criteria-Based Prediction of Sepsis in a Polytrauma Cohort.
    Crit Care Med. 2016.
    PubMed     Text format     Abstract available


  217. GALLAGHER J, Killian AJ, Coopersmith CM
    Is A Diagnosis of Sepsis Sufficient to Warrant Stress Ulcer Prophylaxis?
    Crit Care Med. 2016;44:1450-1452.
    PubMed     Text format    


  218. KLOMPAS M, Rhee C
    We Need Better Tools for Sepsis Surveillance.
    Crit Care Med. 2016;44:1441-1442.
    PubMed     Text format    


  219. KEMPKER JA, Martin GS
    Sepsis to the Fore: Taking the Lead in Critical Care Admissions.
    Crit Care Med. 2016;44:1435-1436.
    PubMed     Text format    


  220. REILLY JP
    Predicting and Eventually Preventing the Future: Sepsis Risk in Community-Dwelling Adults.
    Crit Care Med. 2016;44:1425-1426.
    PubMed     Text format    


    June 2016
  221. HONORE PM, Nguyen HB, Gong M, Chawla LS, et al
    Urinary Tissue Inhibitor of Metalloproteinase-2 and Insulin-Like Growth Factor-Binding Protein 7 for Risk Stratification of Acute Kidney Injury in Patients With Sepsis.
    Crit Care Med. 2016.
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  222. SHANKAR-HARI M, Harrison DA, Rowan KM
    Differences in Impact of Definitional Elements on Mortality Precludes International Comparisons of Sepsis Epidemiology-A Cohort Study Illustrating the Need for Standardized Reporting.
    Crit Care Med. 2016.
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  223. KISSOON N, Daniels R, van der Poll T, Finfer S, et al
    Sepsis-The Final Common Pathway to Death From Multiple Organ Failure in Infection.
    Crit Care Med. 2016;44:e446.
    PubMed     Text format    


  224. SEELY AJ
    Treating Sepsis: Nearest Neighbors and Predicting Beginnings.
    Crit Care Med. 2016;44:1261-2.
    PubMed     Text format    


  225. CHEN J, Thiemermann C
    Selenium and Niacin for Sepsis Therapy: The Sum Is Greater Than Its Parts.
    Crit Care Med. 2016;44:1256-7.
    PubMed     Text format    


  226. GALVAGNO SM JR
    Outcomes Following Sepsis and Cardiopulmonary Resuscitation: Fare Thee Well or Worse for Wear?
    Crit Care Med. 2016;44:1232-3.
    PubMed     Text format    


  227. MARIK PE
    "Vitamin S" (Steroids) and Vitamin C for the Treatment of Severe Sepsis and Septic Shock!
    Crit Care Med. 2016;44:1228-9.
    PubMed     Text format    


    May 2016
  228. MOORMAN JR, Lake DE, Ivanov PC
    Early Detection of Sepsis-A Role for Network Physiology?
    Crit Care Med. 2016;44:e312-e313.
    PubMed     Text format    


  229. GUENANCIA C, Laurent G, Bruyere R, Quenot JP, et al
    New-Onset Atrial Fibrillation in Sepsis: So Common, but So Different.
    Crit Care Med. 2016;44:e306-e307.
    PubMed     Text format    


  230. WARD PA
    In Sepsis, Complement Is Alive and Well.
    Crit Care Med. 2016;44:1026-1027.
    PubMed     Text format    


  231. DEUTSCHMAN CS
    Imprecise Medicine: The Limitations of Sepsis-3.
    Crit Care Med. 2016;44:857-858.
    PubMed     Text format    


  232. VINCENT JL, Sampath R
    The authors reply.
    Crit Care Med. 2016;44:e315.
    PubMed     Text format    


  233. MITTAL S, Mohan A, Guleria R, Agarwal R, et al
    Rapid Diagnosis of Infection in Critically Ill: Is Molecular Diagnosis the Magic Bullet?
    Crit Care Med. 2016;44:e314-5.
    PubMed     Text format    


  234. CONTENTI J, Levraut J
    The authors reply.
    Crit Care Med. 2016;44:e311-2.
    PubMed     Text format    


  235. BOULAIN T, Ehrmann S, Lakhal K
    beta-Blockade and Septic Shock Phenotype.
    Crit Care Med. 2016;44:e310-1.
    PubMed     Text format    


  236. CORDEIRO VENTURA A, Bousso A
    The authors reply.
    Crit Care Med. 2016;44:e310.
    PubMed     Text format    


  237. KLEIBER N, Tromp K, Tibboel D, de Wildt SN, et al
    Trial Recruitment in the Pediatric Intensive Care: Ask Consent Before You Start?!
    Crit Care Med. 2016;44:e309-e310.
    PubMed     Text format    


  238. CORDEIRO VENTURA A
    The author replies.
    Crit Care Med. 2016;44:e308-9.
    PubMed     Text format    


  239. SLAIN KN, Shein SL, Rotta AT
    The Dose Makes the Poison: Comparing Epinephrine With Dopamine in Pediatric Septic Shock.
    Crit Care Med. 2016;44:e308.
    PubMed     Text format    


    April 2016
  240. SHEN HN, Lu CL, Yang HH
    Risk of Recurrence After Surviving Severe Sepsis: A Matched Cohort Study.
    Crit Care Med. 2016.
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  241. MOORE JX, Donnelly JP, Griffin R, Howard G, et al
    Defining Sepsis Mortality Clusters in the United States.
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  242. NEUGEBAUER S, Giamarellos-Bourboulis EJ, Pelekanou A, Marioli A, et al
    Metabolite Profiles in Sepsis: Developing Prognostic Tools Based on the Type of Infection.
    Crit Care Med. 2016.
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  243. SASSOON CS, Zhu E, Fang L, Subramanian VS, et al
    Inhibition of Intestinal Thiamin Transport in Rat Model of Sepsis.
    Crit Care Med. 2016.
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  244. GENGA K, Russell JA
    Early Liberal Fluids for Sepsis Patients Are Harmful.
    Crit Care Med. 2016.
    PubMed     Text format    


  245. ALAM N, Nanayakkara PW
    Time for a Randomized Controlled Trial to Investigate Optimal Time to Antibiotics for Patients With Sepsis.
    Crit Care Med. 2016;44:e236-7.
    PubMed     Text format    


  246. KUMAR A
    Systematic Bias in Meta-Analyses of Time to Antimicrobial in Sepsis Studies.
    Crit Care Med. 2016;44:e234-5.
    PubMed     Text format    


  247. DONG JZ, Wang LP, Zhu JH
    Appropriate Antibiotic Therapy and WBC in Sepsis: Factors to Consider.
    Crit Care Med. 2016;44:e231.
    PubMed     Text format    


  248. SCHEER C, Fuchs C, Rehberg S
    Biomarkers in Severe Sepsis and Septic Shock: Just Listen to the Heart?
    Crit Care Med. 2016;44:849-50.
    PubMed     Text format    


  249. GELOEN A, Quintin L
    Reverse Physiology, i.e., Cellular Versus Integrative Versus Comparative Physiology? alpha-2 Agonists and Septic Shock.
    Crit Care Med. 2016;44:e238-9.
    PubMed     Text format    


  250. STERLING SA, Puskarich MA, Jones AE
    The authors reply.
    Crit Care Med. 2016;44:e237.
    PubMed     Text format    


  251. STERLING SA, Puskarich MA, Jones AE
    The authors reply.
    Crit Care Med. 2016;44:e235-6.
    PubMed     Text format    


  252. VENTURA AC, Goes PF
    The authors reply.
    Crit Care Med. 2016;44:e233-4.
    PubMed     Text format    


  253. COLLETI J JR, de Carvalho WB
    First-Line Vasoactive Drugs for Pediatric Septic Shock: Changing the Paradigm?
    Crit Care Med. 2016;44:e232-3.
    PubMed     Text format    


  254. KOLLEF MH, Micek ST
    The authors reply.
    Crit Care Med. 2016;44:e231-2.
    PubMed     Text format    


  255. OSTHOFF M, Sidler JA, Lakatos B, Frei R, et al
    Low-Dose Acetylsalicylic Acid Treatment and Impact on Short-Term Mortality in Staphylococcus aureus Bloodstream Infection: A Propensity Score-Matched Cohort Study.
    Crit Care Med. 2016;44:773-81.
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  256. THIERY-ANTIER N, Binquet C, Vinault S, Meziani F, et al
    Is Thrombocytopenia an Early Prognostic Marker in Septic Shock?
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  257. BRASSARD P, Zaar M, Thaning P, Secher NH, et al
    Sympathetic Vasoconstrictor Responsiveness of the Leg Vasculature During Experimental Endotoxemia and Hypoxia in Humans.
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  258. MINEJIMA E, Bensman J, She RC, Mack WJ, et al
    A Dysregulated Balance of Proinflammatory and Anti-Inflammatory Host Cytokine Response Early During Therapy Predicts Persistence and Mortality in Staphylococcus aureus Bacteremia.
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  259. ATKINSON SJ, Nolan M, Klingbeil L, Harmon K, et al
    Intestine-Derived Matrix Metalloproteinase-8 Is a Critical Mediator of Polymicrobial Peritonitis.
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  260. JENNEWEIN C, Tran N, Kanczkowski W, Heerdegen L, et al
    Mortality of Septic Mice Strongly Correlates With Adrenal Gland Inflammation.
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  261. RHEE C
    Cytokine Imbalance Predicts Poor Outcomes in Staphylococcus aureus Bacteremia--But What Can We Do About It?
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    March 2016
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    Derivation of Novel Risk Prediction Scores for Community-Acquired Sepsis and Severe Sepsis.
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  263. SMITH JA, Mayeux PR, Schnellmann RG
    Delayed Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Inhibition by Trametinib Attenuates Systemic Inflammatory Responses and Multiple Organ Injury in Murine Sepsis.
    Crit Care Med. 2016.
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  264. SASABUCHI Y, Matsui H, Lefor AK, Fushimi K, et al
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    Crit Care Med. 2016.
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  265. YENDE S, Austin S, Rhodes A, Finfer S, et al
    Long-Term Quality of Life Among Survivors of Severe Sepsis: Analyses of Two International Trials.
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  266. ZHANG LA, Parker RS, Swigon D, Banerjee I, et al
    A One-Nearest-Neighbor Approach to Identify the Original Time of Infection Using Censored Baboon Sepsis Data.
    Crit Care Med. 2016.
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  267. VAN VUGHT LA, Wiewel MA, Klein Klouwenberg PM, Hoogendijk AJ, et al
    Admission Hyperglycemia in Critically Ill Sepsis Patients: Association With Outcome and Host Response.
    Crit Care Med. 2016.
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  268. BAUMBACH P, Gotz T, Gunther A, Weiss T, et al
    Prevalence and Characteristics of Chronic Intensive Care-Related Pain: The Role of Severe Sepsis and Septic Shock.
    Crit Care Med. 2016.
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  269. LIU ZJ, Liu JL, Qu HP
    Could Lactate Become a Biomarker of Hypoxia and a Target of Resuscitation in Sepsis?
    Crit Care Med. 2016;44:e178.
    PubMed     Text format    


  270. SEYMOUR CW, Coopersmith CM, Deutschman CS, Gesten F, et al
    Application of a Framework to Assess the Usefulness of Alternative Sepsis Criteria.
    Crit Care Med. 2016;44:e122-30.
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  271. ANGUS DC, Seymour CW, Coopersmith CM, Deutschman CS, et al
    A Framework for the Development and Interpretation of Different Sepsis Definitions and Clinical Criteria.
    Crit Care Med. 2016;44:e113-21.
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  272. PRESCOTT HC
    Toward a Nuanced Understanding of the Role of Infection in Readmissions After Sepsis.
    Crit Care Med. 2016;44:634-5.
    PubMed     Text format    


  273. CASSERLY B, Levy MM
    The authors reply.
    Crit Care Med. 2016;44:e178-9.
    PubMed     Text format    


  274. WILLIAMS JM, Greenslade JH, Chu K, Brown AF, et al
    Severity Scores in Emergency Department Patients With Presumed Infection: A Prospective Validation Study.
    Crit Care Med. 2016;44:539-47.
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  275. HAWARI FI, Nazer LH, Addassi A, Rimawi D, et al
    Predictors of ICU Admission in Patients With Cancer and the Related Characteristics and Outcomes: A 5-Year Registry-Based Study.
    Crit Care Med. 2016;44:548-53.
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  276. MIKACENIC C, Hansen EE, Radella F, Gharib SA, et al
    Interleukin-17A Is Associated With Alveolar Inflammation and Poor Outcomes in Acute Respiratory Distress Syndrome.
    Crit Care Med. 2016;44:496-502.
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    February 2016
  277. LEWIS AJ, Yuan D, Zhang X, Angus DC, et al
    Use of Biotelemetry to Define Physiology-Based Deterioration Thresholds in a Murine Cecal Ligation and Puncture Model of Sepsis.
    Crit Care Med. 2016.
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  278. BURNHAM JP, Kollef MH
    Timing of Appropriate Antibiotics in Sepsis: How Much Does Each Hour Matter?
    Crit Care Med. 2016;44:e109-10.
    PubMed     Text format    


  279. JOHNSON DW, Kalil AC
    Is Interleukin-1 Receptor Blockade Ready for Prime Time in Patients With Severe Sepsis and Macrophage Activation Syndrome?
    Crit Care Med. 2016;44:443-4.
    PubMed     Text format    


  280. CORDEIRO VENTURA A, Shieh HH
    The authors reply.
    Crit Care Med. 2016;44:e111-2.
    PubMed     Text format    


  281. LALGUDI GANESAN S, Jayashree M
    Dopamine in Pediatric Fluid-Refractory Septic Shock: Too Early to Sound the Death Knell?
    Crit Care Med. 2016;44:e110-1.
    PubMed     Text format    


  282. STERLING SA, Puskarich MA, Jones AE
    The authors reply.
    Crit Care Med. 2016;44:e110.
    PubMed     Text format    


  283. CROSS A
    Endotoxin: Back to the Future.
    Crit Care Med. 2016;44:450-1.
    PubMed     Text format    


  284. SWEENEY DA, Kalil AC
    Choosing the Duration of Therapy for Bacteremia: Keep Calm and Work With Your Infectious Disease and Antibiotic Stewardship Colleagues.
    Crit Care Med. 2016;44:439-40.
    PubMed     Text format    


  285. DONNINO MW, Andersen LW, Chase M, Berg KM, et al
    Randomized, Double-Blind, Placebo-Controlled Trial of Thiamine as a Metabolic Resuscitator in Septic Shock: A Pilot Study.
    Crit Care Med. 2016;44:360-7.
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  286. CHARBONNEY E, Tsang JY, Li Y, Klein D, et al
    Endotoxemia Following Multiple Trauma: Risk Factors and Prognostic Implications.
    Crit Care Med. 2016;44:335-41.
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  287. DANEMAN N, Rishu AH, Xiong W, Bagshaw SM, et al
    Duration of Antimicrobial Treatment for Bacteremia in Canadian Critically Ill Patients.
    Crit Care Med. 2016;44:256-64.
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    January 2016
  288. LI D, Zou L, Feng Y, Xu G, et al
    Complement Factor B Production in Renal Tubular Cells and Its Role in Sodium Transporter Expression During Polymicrobial Sepsis.
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  289. STANDAGE SW, Waworuntu RL, Delaney MA, Maskal SM, et al
    Nonhematopoietic Peroxisome Proliferator-Activated Receptor-alpha Protects Against Cardiac Injury and Enhances Survival in Experimental Polymicrobial Sepsis.
    Crit Care Med. 2016.
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  290. NEYRA JA, Canepa-Escaro F, Yee J, Yessayan L, et al
    The authors reply.
    Crit Care Med. 2016;44:e53-4.
    PubMed     Text format    


  291. JO S, Jeong T, Lee JB, Jin YH, et al
    Hyperchloremia Versus Nonhyperchloremia or Hyperchloremia Versus Normochloremia?
    Crit Care Med. 2016;44:e53.
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  292. KOLLEF MH, Burnham JP
    The authors reply.
    Crit Care Med. 2016;44:e50-1.
    PubMed     Text format    


  293. ROUX D, Pons S, Guillard T, Ricard JD, et al
    Impact of Drug Resistance on Virulence and Fitness of Bacterial Pathogens.
    Crit Care Med. 2016;44:e50.
    PubMed     Text format    


  294. CROWLEY JC, Gropper MA
    IV Immunoglobulin: A Useful Tool for the Severe Pneumonia Toolbox?
    Crit Care Med. 2016;44:250-1.
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  295. ASFAR P, Russell JA, Tuckermann J, Radermacher P, et al
    Selepressin in Septic Shock: A Step Toward Decatecholaminization?
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  296. HE X, Su F, Taccone FS, Laporte R, et al
    A Selective V(1A) Receptor Agonist, Selepressin, Is Superior to Arginine Vasopressin and to Norepinephrine in Ovine Septic Shock.
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  297. KATOH H, Yasumoto H, Shimizu M, Hamaoka S, et al
    IV Immunoglobulin for Acute Lung Injury and Bacteremia in Pseudomonas aeruginosa Pneumonia.
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    December 2015
  298. STARR ME, Steele AM, Cohen DA, Saito H, et al
    Short-Term Dietary Restriction Rescues Mice From Lethal Abdominal Sepsis and Endotoxemia and Reduces the Inflammatory/Coagulant Potential of Adipose Tissue.
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  299. KWON WY, Suh GJ, Kim KS, Jung YS, et al
    Niacin and Selenium Attenuate Sepsis-Induced Lung Injury by Up-Regulating Nuclear Factor Erythroid 2-Related Factor 2 Signaling.
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  300. WRIGHT BJ, Weingart SD
    beta-Blockers and Lactate in Sepsis: Same Canary But Different Mine.
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  301. TYRON C, Huber J, Hsu B
    1304: IMPACT OF DEPRESSION ON RECOVERY AND COSTS OF SEVERE SEPSIS WITHIN THE ADOLESCENT POPULATION.
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  302. OMRANIAN A, Senussi M, Gill H, Nandyala S, et al
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  303. LEES N, Rosenberg A, Popov A, Hurtado-Doce A, et al
    1238: COMBINATION ECMO AND CYTOKINE ADSORPTION THERAPY FOR SEVERE SEPSIS WITH CARDIOGENIC SHOCK AND ARDS.
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  304. SINHA S, Pati J
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  306. MEYER B, Wenisch C, Haider D, Neuhold S, et al
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  307. ZHOU F, Hongjun K, Hui L, Liang P, et al
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  309. BITTNER E, Linde-Zwirble W, Hansell D, Sahatjian J, et al
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  311. GANDHI A, Patel R, Victor N
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  312. KATO T, Matsuura K, Nakagawa T, Miki Y, et al
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    1091: EVALUATION OF THE PROGNOSIS OF SEPSIS WITH MASS SPECTROMETRY.
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  314. ARMAIGNAC D, Fuxa H, Lamoureux J, Valle C, et al
    1090: ARE THE CURRENT DEFINITIONS USED TO DETECT SEPSIS ADEQUATE FOR PREDICTION OF SEPSIS SYNDROME?
    Crit Care Med. 2015;43.
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  315. YNOSENCIO T, Smith A, Endicott-Yazdani T, Gardner R, et al
    1089: CO-MORBIDITIES IN SEPSIS AND SEPSIS RELATED DEATHS.
    Crit Care Med. 2015;43.
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  316. SHIH YN, Chen YT, Seethala R, Aisiku I, et al
    1088: EFFECT OF THE USE OF THEOPHYLLINE AND SEPSIS OUTCOMES.
    Crit Care Med. 2015;43.
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  317. BANSAL V, Mangi M, Moreno-Franco P, Emir F, et al
    1087: OBSTRUCTIVE SLEEP APNEA DOES NOT MODIFY SEPSIS SEVERITY AND RELATED OUTCOMES.
    Crit Care Med. 2015;43.
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  318. SANUTH B, Wang K
    1084: EVALUATION OF CODE SEPSIS AT A URBAN COMMUNITY TEACHING HOSPITAL.
    Crit Care Med. 2015;43.
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  319. HAN M, Fitzgerald J, Balamuth F, Chilutti M, et al
    1083: HOURLY DELAYS TO ANTIMICROBIAL THERAPY DO NOT INCREASE ONE-YEAR MORTALITY IN PEDIATRIC SEVERE SEPSIS.
    Crit Care Med. 2015;43.
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  320. PAPPADA S, Feeney J, Papadimos T, Salinas J, et al
    1082: INVESTIGATING A NOVEL SEPSIS RISK INDEX FOR USE IN AN INTELLIGENT ANTIBIOTIC DECISION SUPPORT SYSTEM.
    Crit Care Med. 2015;43.
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  321. AN G, Cockrell C
    1081: SUPERCOMPUTING SIMULATION OF 40 MILLION IN SILICO PATIENTS TO CHARACTERIZE THE LANDSCAPE OF SEPSIS.
    Crit Care Med. 2015;43.
    PubMed     Text format    


  322. KRUER R, Rozycki A, Jarrell A
    1079: EVALUATION OF A SEVERE SEPSIS ORDER SET IN THE SURGICAL ICU.
    Crit Care Med. 2015;43.
    PubMed     Text format    


  323. NICOLAS L, Samraj R, Philip J
    1078: UTILITY OF NIRS FOR OUTCOME PREDICTION IN CRITICALLY ILL CHILDREN WITH SEPSIS/SEPTIC SHOCK.
    Crit Care Med. 2015;43.
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  324. GENESE F, Martillo M, Ventura I, Fuhrmann K, et al
    1075: THE INFLUENCE OF SEPSIS ON SLEEP ARCHITECTURE IN THE ICU.
    Crit Care Med. 2015;43.
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  325. CARRINGTON J, Szczybor P, Barnes J
    1074: MAKING SIGNIFICANT REDUCTIONS IN REPORTABLE SEPSIS MORTALITY DATA: ACCURATE CLASSIFICATION IS KEY.
    Crit Care Med. 2015;43.
    PubMed     Text format    


  326. MATHIEU JF, Boucher S, Pellerin JP
    1073: NEW HEMOSTATIC SCORE ADDING PROTEIN-C AND ANTITHROMBIN MAY BETTER IDENTIFY SEPSIS-INDUCED COAGULOPATHY.
    Crit Care Med. 2015;43.
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  327. PATEL C, Kuo YH, Casey K, Rojtman A, et al
    1072: PROCALCITONIN AS A MARKER OF SEPSIS IN CARDIAC AND NON-CARDIAC RAPID RESPONSES.
    Crit Care Med. 2015;43.
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  328. ZHOU H, Deng M, Scott M, Neal M, et al
    1071: PLATELET HMGB1 REGULATES NEUTROPHIL RECRUITMENT AND PLATELET NEUTROPHIL INTERACTION DURING SEPSIS.
    Crit Care Med. 2015;43.
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  329. GASPERINO J, Gabriel-Jocson E, Perez E, Levy R, et al
    1069: SEPSIS WITHOUT WALLS: A QUALITY IMPROVEMENT PROJECT.
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  330. RUSSELL J, Boyd J, Fineberg D, Lee T, et al
    1066: PREVALENCE AND CHARACTERISTICS OF EARLY SEPSIS ASSOCIATED COAGULOPATHY.
    Crit Care Med. 2015;43.
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  331. JASMINE N, Pillai V, Periyaveedu S, Warrier A, et al
    1065: SCRUB TYPHUS: AN EMERGING CAUSE OF SEVERE SEPSIS IN THE ICU AND NEED FOR ANTIBIOTIC PROTOCOL MODIFICATION.
    Crit Care Med. 2015;43.
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  332. FERGUSON K, Vandergrift MA
    1064: THORACIC IMPEDANCE CARDIOGRAPHY IN MONITORING SEVERE SEPSIS RESUSCITATION.
    Crit Care Med. 2015;43.
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  333. IKE C, Freibott P, Myers K, Sabo J, et al
    1061: IMPACT OF ORDER SET UTILIZATION FOR THE TREATMENT OF PATIENTS WITH SEVERE SEPSIS AND SEPTIC SHOCK.
    Crit Care Med. 2015;43.
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  334. GROTH M, Chernosky M, Farrell L, Grennen M, et al
    1058: OUTCOMES OF SEPSIS AND COMPLIANCE WITH SEPSIS BUNDLES IN A COMMUNITY NON-TEACHING HOSPITAL.
    Crit Care Med. 2015;43.
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  335. ENDICOTT-YAZDANI T, Gardner R, Smith A, Tsai-Nguyen G, et al
    1054: LACTIC ACID IN SEPSIS AND SEPSIS RELATED DEATHS.
    Crit Care Med. 2015;43.
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  336. ADAMS C, Tucker C, Allen B, Loudy M, et al
    1051: EFFICACY OF NON-WEIGHT BASED VASOPRESSOR DOSING IN CRITICALLY ILL PATIENTS WITH SEVERE SEPSIS.
    Crit Care Med. 2015;43.
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  337. MOLUGU C, Hill A, Hall J
    1049: PATIENT UNDERSTANDING SURROUNDING SEPSIS EVALUATION (PURSE).
    Crit Care Med. 2015;43.
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  338. RECH M, Sowinski-Raff L, Young K, Kule A, et al
    1048: VITAMIN D SUPPLEMENTATION AND MORTALITY IN PATIENTS WITH SEVERE SEPSIS AND SEPTIC SHOCK.
    Crit Care Med. 2015;43.
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  339. EMRATH E, Travers C, McCracken C, Fortenberry J, et al
    1047: RESUSCITATION WITH BALANCED FLUIDS IS ASSOCIATED WITH IMPROVED SURVIVAL IN PEDIATRIC SEVERE SEPSIS.
    Crit Care Med. 2015;43.
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  340. WHILES B, Deis A, Miller P, Simpson S, et al
    1044: IMPACT OF INITIAL ANTIBIOTIC CHOICE ON OUTCOMES AMONG PATIENTS WITH SEVERE SEPSIS AND SEPTIC SHOCK.
    Crit Care Med. 2015;43.
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  341. BINEY I, Amin R, Mehari A
    1043: SHOCK INDEX AS A PREDICTOR OF ICU TRANSFER IN PATIENTS ADMITTED TO THE MEDICAL WARD WITH SEPSIS.
    Crit Care Med. 2015;43.
    PubMed     Text format    


  342. MENG YH, Chen KF
    1042: EFFECTS OF STATIN AND FIBRATE ON OUTCOMES OF SEPSIS.
    Crit Care Med. 2015;43.
    PubMed     Text format    


  343. SHAH H, Rezai F, Kellner F, Handler E, et al
    1038: EVALUATING INITIATIVES ADVOCATING APPROPRIATE FLUID THERAPY IN SEVERE SEPSIS/SEPTIC SHOCK.
    Crit Care Med. 2015;43.
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  344. ZHANG LA, Banerjee I, Swigon D, Parker R, et al
    1037: USING VITALS AND A SINGLE BLOOD BIOMARKER TO PREDICT DISEASE TIME ZERO IN ANIMAL MODELS OF SEPSIS.
    Crit Care Med. 2015;43.
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  345. SIGNOFF J, Fitzgerald J, Teachey D, Balamuth F, et al
    1034: HYPOFIBRINOGENEMIA IS ASSOCIATED WITH POOR OUTCOME AND SECONDARY HLH IN PEDIATRIC SEVERE SEPSIS.
    Crit Care Med. 2015;43.
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  346. GORGIS N, Fontana C, Asselin J, Heidersbach R, et al
    1033: IS INITIAL LACTATE A RELIABLE PREDICTOR OF OUTCOME IN PEDIATRIC SEVERE SEPSIS AND SEPTIC SHOCK?
    Crit Care Med. 2015;43.
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  347. SIDDIQUI F, Pelleg T, Ie S
    1032: IMPACT OF SEPSIS ALERT PROCESS IN IMPROVING CLINICAL OUTCOMES.
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  348. HAILESELASSIE B, Su E, Pozios I, Willett R, et al
    1031: SPECKLE TRACKING STRAIN ECHOCARDIOGRAPHY: A METRIC OF CARDIAC DYSFUNCTION IN A RODENT SEPSIS MODEL.
    Crit Care Med. 2015;43.
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  349. ALQAHTANI M, Dawson S, Ranaivo HR, Smith C, et al
    1030: BIOMARKERS IN PEDIATRIC SEPSIS: MMP-9, TIMP-1, MRPROANP, AND ADIPOCYTE FATTY-ACID BINDING PROTEIN.
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    PubMed     Text format    


  350. MEREDITH K, Olsen M, Hartman M
    1029: THE COMPARATIVE EPIDEMIOLOGY OF PEDIATRIC SEVERE SEPSIS.
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  351. ADAMS J, Uryash A, Lopez J, Sackner M, et al
    1028: NON-INVASIVE PREVENTATIVE AND THERAPEUTIC APPROACH TO REDUCE MORTALITY FROM SEPSIS.
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  352. PERRY M, Ali N, Mount K, Ryder L, et al
    1027: ASSOCIATION BETWEEN INTRAVENOUS FLUID CHLORIDE CONTENT AND ACUTE KIDNEY INJURY IN ADULTS WITH SEPSIS.
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  353. SHIH YN, Chen YT, Seethala R, Aisiku I, et al
    1026: THE ASSOCIATION BETWEEN WEEKEND EFFECT AND EARLY MORTALITY IN SEVERE SEPSIS PATIENTS OVER TIME.
    Crit Care Med. 2015;43.
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  354. COAN A, DeSai A, Gadhvi S, Milligan Z, et al
    1025: SIMULATION TRAINING IMPROVES RESIDENTS KNOWLEDGE AND ADHERENCE TO THE SURVIVING SEPSIS GUIDELINES.
    Crit Care Med. 2015;43.
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  355. ZIMMERMAN J, Sullivan E, Sampson D, McHugh L, et al
    1024: SENSITIVE AND SPECIFIC DIAGNOSIS OF SEPSIS IN CRITICALLY ILL CHILDREN UTILIZING HOST GENE EXPRESSION.
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  356. MAHAPATRA S, Kurnellas M, Rothbard J, Steinman L, et al
    1023: EXPLORING THE ANTI-INFLAMMATORY EFFECTS OF THE AMYLOIDOGENIC HEXAPEPTIDE, AMYLIN28-33, IN SEPSIS.
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  357. SZAKMANY T, Ellis G, Sharif B, Lundin R, et al
    1021: SIZE OF SEPSIS IN WALES: A NATIONWIDE POINT-PREVALENCE STUDY.
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  358. STREET J, Glispie D, Huang Y, Yuen P, et al
    1020: GFR IN CONSCIOUS MICE AFTER SEPSIS: ROLE OF TUBULOGLOMERULAR FEEDBACK.
    Crit Care Med. 2015;43.
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  359. TAKAHASHI H, Kuriyama K, Yoshikawa K, Ueki Y, et al
    1019: EFFICACY OF RECOMBINANT THROMBOMODULIN AND ANTITHROMBIN COMBINATION THERAPY IN SEPSIS-INDUCED DIC.
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  360. PARK J, Chang Y, Heo J, Hong MK, et al
    1016: CLINICAL SIGNIFICANCE OF SERIAL CHANGES IN PLASMA SURFACTANT PROTEIN D IN PATIENTS WITH SEPSIS.
    Crit Care Med. 2015;43.
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  361. KUTTAB H, Williams C, Wilson A, Murphy M, et al
    1014: ABO BLOOD TYPE A AND INCREASED SEVERITY OF SEPSIS.
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  362. MCINTOSH A, Schmidt S, Tong S, Deakyne S, et al
    1013: VALIDATION OF THE VASOACTIVE INOTROPIC SCORE IN PEDIATRIC SEPSIS.
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  363. KOPTERIDES P, Chang JC, Angus D, Opal S, et al
    1007: ORGAN SUPPORT-BASED SURROGATE OUTCOME MEASURE FOR SEPSIS TRIALS.
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  364. SIMON D, Podd B, Clark R, Carcillo J, et al
    1003: HYPERFERRITINEMIA IN PEDIATRIC SEVERE SEPSIS.
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  365. MILLER R, Lopansri B, McHugh L, Rapisarda A, et al
    1002: VALIDATION OF A NOVEL HOST RESPONSE ASSAY TO DISTINGUISH SIRS AND SEPSIS IN CRITICALLY ILL PATIENTS.
    Crit Care Med. 2015;43.
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  366. KOPTERIDES P, Diane I, Lucko N, Shapiro N, et al
    1001: REHOSPITALIZATIONS AND FATAL OUTCOME ARE COMMON AMONG SEVERE SEPSIS SURVIVORS.
    Crit Care Med. 2015;43.
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  367. PANG D, Wu Y, Cummings J, Hsue V, et al
    1000: NEURORADIOLOGIC AND HISTOPATHOLOGIC CORRELATES OF BRAIN INJURY IN A MURINE MODEL OF SEPSIS.
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  368. CHANTRA M, Prom-On S, Lertbunrian R, Anantasit N, et al
    999: CARDIAC TROPONIN T AS A PREDICTOR OF SEVERITY IN PEDIATRIC SEPSIS.
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  369. DI CARO V, Cummings J, Pang D, Hsue V, et al
    994: DIETARY FIBER SUPPLEMENTATION CONFERS PROTECTION IN A MURINE MODEL OF SEPSIS.
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  370. UEMURA T, Hiruma H, Hagiwara A, Makinouchi R, et al
    992: EFFECTS OF RECOMBINANT HUMAN THROMBOMODULIN ON SEPSIS-INDUCED DISSEMINATED INTRAVASCULAR COAGULATION.
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  371. PARK I, Choe K, Hwang Y, Seo H, et al
    991: IDENTIFYING PULMONARY MICROCIRCULATION OF MURINE SEPSIS MODEL USING INTRAVITAL MICROSCOPY.
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  372. ZHU L, Clermont G, Zhang LA, Mochan-Keef E, et al
    990: USING BIOMARKERS TO ENHANCE 60-DAY IN HOSPITAL MORTALITY PREDICTION FOR EARLY SEPSIS PATIENT.
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  373. SHERWIN R, Courage C, Ying H
    989: A COMPUTER-BASED DECISION SUPPORT TOOL ACCURATELY IDENTIFIES SEVERE SEPSIS IN ED PATIENTS.
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  374. SAITO N, Suzuki H, Shibahara K, Akiduki N, et al
    987: RHS-TM COULD CONTRIBUTE TO INHIBIT THROMBIN GENERATION IN SEPSIS-INDUCED DIC.
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  375. KURODA K, Morimatsu H, Wake H, Mori S, et al
    986: HISTIDINE-RICH GLYCOPROTEIN AS A NEW BIOMARKER FOR SEPSIS: COMPARISON TO PROCALCITONIN AND PRESEPSIN.
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  376. ZAND O, Garimella S, Najdzionek I, Hassinger A, et al
    985: USE OF NONINVASIVE METHODS TO DETECT SEPSIS-INDUCED ACUTE KIDNEY INJURY IN CRITICALLY ILL CHILDREN.
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  377. BORGES N, Kennedy C, Cruz A, Patel B, et al
    940: CHOOSING TIME ZERO CRITICALLY AFFECTS QUALITY PERFORMANCE METRICS IN PEDIATRIC SEPSIS.
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  378. MORENO-FRANCO P, Grek A, Maniaci M, Shirazi E, et al
    828: SEPSIS AND SHOCK RESPONSE TEAM: A RECIPE FOR HIGH-QUALITY SURVIVING SEPSIS GUIDELINES IMPLEMENTATION.
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  379. RAFIE K, Goldman J, Thomas T, Chartan C, et al
    764: UNDERSTANDING COMPLEXITY: USING RESILIENCE ENGINEERING TO OPTIMIZE SEPSIS QUALITY IMPROVEMENT.
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  380. IWASHITA Y, Zhang E, Maruyama J, Imai H, et al
    695: THE EFFECT OF RECOMBINANT THROMBOMODULIN ON SEPSIS-PRIMED VENTILATOR-INDUCED LUNG INJURY.
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  381. GRGURICH P, Elfman J, Dargin J, Lei Y, et al
    648: EVALUATION OF THE APPROPRIATENESS OF INITIAL ANTIBIOTIC DOSING IN SEVERE SEPSIS AND SEPTIC SHOCK.
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  382. RASHID A, Hubank M, Kwan A, Klein N, et al
    428: EGF GENE UPREGULATION PERIPHERAL WHITE CELL GENE EXPRESSION IN CHILDREN WITH MENINGOCOCCAL SEPSIS.
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  383. ZILBERBERG M, Nathanson B, Sulham K, Fan W, et al
    300: HOSPITALIZATIONS WITH ACINETOBACTER BAUMANNII PNEUMONIA AND SEPSIS IN THE US.
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  384. GNANASEKARAN J, Ong R, Krinsley J
    287: DIABETES IS ASSOCIATED WITH INCREASED DYSGLYCEMIA AND MORTALITY IN PATIENTS WITH SEPSIS.
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  385. GNANASEKARAN J, Ong R, Krinsley J
    266: THE RELATIONSHIP OF THE SEVERITY OF SEPSIS TO INSULIN RESISTANCE AND DYSGLYCEMIA.
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  386. AYALON I, Kumar Shanmukhappa S, Shen H, Williamson L, et al
    64: OBESITY ALTERS ADIPOSE TISSUE RESPONSE TO SEPSIS THROUGH WHITE TO BROWN TRANSDIFFERENTIATION.
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  387. KATO Y, Shimomura Y, Nagao S, Suga M, et al
    62: EFFECTS OF RECOMBINANT HUMAN THROMBOMODULIN ON NETOSIS IN LPS-INDUCED SEPSIS IN MICE.
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  388. OFOMA U, Dahdah J, Maeng D, Walkey A, et al
    60: CASE VOLUME AND MORTALITY AMONG PATIENTS WITH SEVERE SEPSIS WHO UNDERWENT INTERHOSPITAL TRANSFER.
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  389. CROUSER E, Parrillo J, Angus D, Seymour C, et al
    58: A FEASIBILITY TRIAL TO DETECT SEPSIS IN THE ED BASED UPON BLOOD MONOCYTE VOLUME VARIABILITY.
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  390. SANDQUIST M, Clee M, Patel S, Nagaraj U, et al
    24: HIGH INCIDENCE OF NEUROIMAGING ABNORMALITIES AFTER PEDIATRIC SEPSIS.
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  391. SOLEZ K
    Multibiomarker Article Gives a Taste of What the Era of Regenerative Medicine/Tissue Engineering Pathology Will Be Like.
    Crit Care Med. 2015;43:e599-600.
    PubMed     Text format    


  392. VINCENT JL
    The author replies.
    Crit Care Med. 2015;43:e596-7.
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  393. WALKER CA, Griffith DM, Gray AJ, Datta D, et al
    "Lactate Shift," Rather Than "Lactate Clearance," for Serial Blood Lactate Monitoring?
    Crit Care Med. 2015;43:e596.
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  394. MICKIEWICZ B, Vogel HJ
    The authors reply.
    Crit Care Med. 2015;43:e593.
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  395. VISWAN A, Azim A, Sinha N
    Nuclear Magnetic Resonance-Based Metabolic Markers Can Be a True Signature of Diagnosis in Critical Care Setting.
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  396. JELLY CA, Alston TA
    Release of Endotoxin After an Arrest.
    Crit Care Med. 2015;43:2687-8.
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  397. VAN DEN BERGH WM
    The Big Difference Between Direct and Nonstop Flights Is the Intermediate Stop Along the Way to the Final Destination.
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  398. GRIMALDI D, Sauneuf B, Guivarch E, Ricome S, et al
    High Level of Endotoxemia Following Out-of-Hospital Cardiac Arrest Is Associated With Severity and Duration of Postcardiac Arrest Shock.
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  399. CONTENTI J, Occelli C, Corraze H, Lemoel F, et al
    Long-Term beta-Blocker Therapy Decreases Blood Lactate Concentration in Severely Septic Patients.
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    November 2015
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  401. MASSON S, Caironi P, Fanizza C, Carrer S, et al
    Sequential N-Terminal Pro-B-Type Natriuretic Peptide and High-Sensitivity Cardiac Troponin Measurements During Albumin Replacement in Patients With Severe Sepsis or Septic Shock.
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  402. JIANG S, Zhao X, Zhao Y, He X, et al
    Can Spontaneous Hypothermia Induce Higher Mortality in Sepsis?
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  403. STALLONE JN
    Corticosteroid Therapy in Sepsis: When Is a Good Thing Too Much of a Good Thing?
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  404. HOTCHKISS RS, Crouser E
    Imaging Apoptosis in Sepsis-A Technology We Would Die for!
    Crit Care Med. 2015;43:2506-2508.
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  405. DREWRY AM, Fuller BM, Skrupky LP, Hotchkiss RS, et al
    The authors reply.
    Crit Care Med. 2015;43:e529-30.
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  406. WANG Q, Yokoo H, Takashina M, Sakata K, et al
    Anti-Inflammatory Profile of Levosimendan in Cecal Ligation-Induced Septic Mice and in Lipopolysaccharide-Stimulated Macrophages.
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  407. PANG D, Aneja RK
    Levosimendan for Septic Myocardial Dysfunction: Not Yet Ready for Prime Time.
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  408. ZIMMERMAN JJ
    On the Threshold of a Dream.
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  409. LINDER A, Arnold R, Boyd JH, Zindovic M, et al
    Heparin-Binding Protein Measurement Improves the Prediction of Severe Infection With Organ Dysfunction in the Emergency Department.
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  410. VINCENT JL, Brealey D, Libert N, Abidi NE, et al
    Rapid Diagnosis of Infection in the Critically Ill, a Multicenter Study of Molecular Detection in Bloodstream Infections, Pneumonia, and Sterile Site Infections.
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  411. VENTURA AM, Shieh HH, Bousso A, Goes PF, et al
    Double-Blind Prospective Randomized Controlled Trial of Dopamine Versus Epinephrine as First-Line Vasoactive Drugs in Pediatric Septic Shock.
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  412. AI J, Guo L, Zheng Z, Wang SX, et al
    Corticosteroid Therapy Benefits Septic Mice With Adrenal Insufficiency But Harms Septic Mice Without Adrenal Insufficiency.
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    October 2015
  413. SHAKOORY B, Carcillo JA, Chatham WW, Amdur RL, et al
    Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial.
    Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  414. MASTERSON C, O'Toole D, Leo A, McHale P, et al
    Effects and Mechanisms by Which Hypercapnic Acidosis Inhibits Sepsis-Induced Canonical Nuclear Factor-kappaB Signaling in the Lung.
    Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  415. FORD DW, Goodwin AJ, Simpson AN, Johnson E, et al
    A Severe Sepsis Mortality Prediction Model and Score for Use With Administrative Data.
    Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  416. FAINE BA, Noack JM, Wong T, Messerly JT, et al
    Interhospital Transfer Delays Appropriate Treatment for Patients With Severe Sepsis and Septic Shock: A Retrospective Cohort Study.
    Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  417. SHEN HN, Li CY
    Risk Factors of Readmissions Among Severe Sepsis Survivors.
    Crit Care Med. 2015;43:e461.
    PubMed     Text format    


  418. ZILBERBERG MD, Shorr AF
    Appropriate Antibiotic Treatment in Severe Sepsis and Septic Shock: Timing Is Everything.
    Crit Care Med. 2015;43:2258-9.
    PubMed     Text format    


  419. FEIN IA
    Sepsis Redux: Bigger and Badder Than Ever.
    Crit Care Med. 2015;43:2251-2.
    PubMed     Text format    


  420. RINSCHEN MM
    (Sugar-) Sweet Biomarkers? Clinical Proteomics Enters Sepsis Research.
    Crit Care Med. 2015;43:2245-6.
    PubMed     Text format    


  421. GOODWIN AJ, Rice DA, Simpson KN, Ford DW, et al
    The authors reply.
    Crit Care Med. 2015;43:e461-2.
    PubMed     Text format    


  422. ANNANE D
    Evidence to Practice Gap: The Case of Dopamine.
    Crit Care Med. 2015;43:2259-60.
    PubMed     Text format    


  423. BOERMA EC
    The Future Is Back; Back to the Future!
    Crit Care Med. 2015;43:2253-4.
    PubMed     Text format    


  424. CALZAVACCA P, Evans RG, Bailey M, Bellomo R, et al
    Cortical and Medullary Tissue Perfusion and Oxygenation in Experimental Septic Acute Kidney Injury.
    Crit Care Med. 2015;43:e431-9.
    PubMed     Text format     Abstract available


  425. FAWZY A, Evans SR, Walkey AJ
    Practice Patterns and Outcomes Associated With Choice of Initial Vasopressor Therapy for Septic Shock.
    Crit Care Med. 2015;43:2141-6.
    PubMed     Text format     Abstract available


    September 2015
  426. SUN A, Mikkelsen ME
    The Evolution of Sepsis Performance Metrics: From Mortality to Hospital Readmission.
    Crit Care Med. 2015;43:2031-2.
    PubMed     Text format    


  427. SIVAPALAN P, Staehr Jensen JU
    Timing of Therapy in Sepsis: Are Early Antibiotics Important for Prognosis?
    Crit Care Med. 2015;43:2030-1.
    PubMed     Text format    


  428. DELLINGER RP
    The Future of Sepsis Performance Improvement.
    Crit Care Med. 2015;43:1787-9.
    PubMed     Text format    


  429. ZOU L, Chen HH, Li D, Xu G, et al
    Imaging Lymphoid Cell Death In Vivo During Polymicrobial Sepsis.
    Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  430. FREEBAIRN R
    Action and Reaction: The Role of Catecholamine Agonists and Antagonists in Septic Shock.
    Crit Care Med. 2015;43:2039-40.
    PubMed     Text format    


  431. REILLY JP, Christie JD
    Primed for Injury: Cigarette Smokers and Acute Respiratory Distress Syndrome.
    Crit Care Med. 2015;43:2015-6.
    PubMed     Text format    


  432. NEYRA JA, Canepa-Escaro F, Li X, Manllo J, et al
    Association of Hyperchloremia With Hospital Mortality in Critically Ill Septic Patients.
    Crit Care Med. 2015;43:1938-44.
    PubMed     Text format     Abstract available


  433. CALFEE CS, Matthay MA, Kangelaris KN, Siew ED, et al
    Cigarette Smoke Exposure and the Acute Respiratory Distress Syndrome.
    Crit Care Med. 2015;43:1790-7.
    PubMed     Text format     Abstract available


  434. KIMMOUN A, Louis H, Al Kattani N, Delemazure J, et al
    beta1-Adrenergic Inhibition Improves Cardiac and Vascular Function in Experimental Septic Shock.
    Crit Care Med. 2015;43:e332-40.
    PubMed     Text format     Abstract available


    August 2015
  435. ZONNEVELD R, Molema G, Plotz FB
    Analyzing Neutrophil Morphology, Mechanics, and Motility in Sepsis: Options and Challenges for Novel Bedside Technologies.
    Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  436. GUTIERREZ JUNCO SM, Paipa Merchan AJ, Heredia Rodriguez M, Gomez Herreras JI, et al
    The Resuscitation Bundle of the Surviving Sepsis Campaign Beyond Early Goal-Directed Therapy: What's Next?
    Crit Care Med. 2015;43:e319-e320.
    PubMed     Text format    


  437. GINGO MR, Morris A
    HIV Infection and Severe Sepsis: A Bitter Pill to Swallow.
    Crit Care Med. 2015;43:1779-1781.
    PubMed     Text format    


  438. HARRISON AM, Herasevich V, Gajic O
    Automated Sepsis Detection, Alert, and Clinical Decision Support: Act on It or Silence the Alarm?
    Crit Care Med. 2015;43:1776-1777.
    PubMed     Text format    


  439. LEVY MM, Townsend SR, Schorr C, Dellinger RP, et al
    The authors reply.
    Crit Care Med. 2015;43:e320-1.
    PubMed     Text format    


  440. MADSEN TE, Napoli AM
    Factors Associated With Progression to Septic Shock: Why Gender?
    Crit Care Med. 2015;43:e319.
    PubMed     Text format    


  441. WONG HR, Cvijanovich NZ, Anas N, Allen GL, et al
    A Multibiomarker-Based Model for Estimating the Risk of Septic Acute Kidney Injury.
    Crit Care Med. 2015;43:1646-53.
    PubMed     Text format     Abstract available


  442. LIPMAN J, Roberts J
    Does Appropriate Antibiotic Therapy Mean Only Adequate Spectrum and Timing?
    Crit Care Med. 2015;43:1773-4.
    PubMed     Text format    


    July 2015
  443. GUINOT PG, Dupont H, Longrois D
    Some Questioning About the Assessment of Renal Perfusion in Sepsis.
    Crit Care Med. 2015;43:e262-4.
    PubMed     Text format    


  444. SAUTHOFF H, Hay JG
    New Drug for Sepsis on the Cheap?
    Crit Care Med. 2015;43:1551-2.
    PubMed     Text format    


  445. HIGGINS TL
    Variability in Risk-Adjusted Sepsis Mortality: How Much Is Too Much?
    Crit Care Med. 2015;43:1530-1.
    PubMed     Text format    


  446. SCHNELL D, Darmon M
    The authors reply.
    Crit Care Med. 2015;43:e264.
    PubMed     Text format    


  447. GRADWOHL-MATIS I, Dunser MW
    Reverse Physiology: Applying an Antihypertensive Drug to Increase Arterial Blood Pressure in Septic Shock.
    Crit Care Med. 2015;43:1548-50.
    PubMed     Text format    


  448. RAMSEY KM, Akula SM
    Co-Reactivation of Cytomegalovirus and Human Herpesvirus-6 Among ICU Patients: There's Smoke, But Is There Fire?
    Crit Care Med. 2015;43:1539-40.
    PubMed     Text format    


  449. EFRON PA, Mohr AM
    The Monocyte That Wasn't.
    Crit Care Med. 2015;43:1532-4.
    PubMed     Text format    


  450. JIA P, Teng J, Zou J, Fang Y, et al
    Xenon Protects Against Septic Acute Kidney Injury via miR-21 Target Signaling Pathway.
    Crit Care Med. 2015;43:e250-9.
    PubMed     Text format     Abstract available


  451. LOPEZ ROA P, Hill JA, Kirby KA, Leisenring WM, et al
    Coreactivation of Human Herpesvirus 6 and Cytomegalovirus Is Associated With Worse Clinical Outcome in Critically Ill Adults.
    Crit Care Med. 2015;43:1415-22.
    PubMed     Text format     Abstract available


    June 2015
  452. CHANG DW, Tseng CH, Shapiro MF
    Rehospitalizations Following Sepsis: Common and Costly.
    Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  453. STERLING SA, Miller WR, Pryor J, Puskarich MA, et al
    The Impact of Timing of Antibiotics on Outcomes in Severe Sepsis and Septic Shock: A Systematic Review and Meta-Analysis.
    Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  454. ZHANG D, Micek ST, Kollef MH
    Time to Appropriate Antibiotic Therapy Is an Independent Determinant of Postinfection ICU and Hospital Lengths of Stay in Patients With Sepsis.
    Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  455. ALHAMDI Y, Abrams ST, Cheng Z, Jing S, et al
    Circulating Histones Are Major Mediators of Cardiac Injury in Patients With Sepsis.
    Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  456. PAGE DB, Donnelly JP, Wang HE
    Community-, Healthcare-, and Hospital-Acquired Severe Sepsis Hospitalizations in the University HealthSystem Consortium.
    Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  457. KOHLHAUER M, Lidouren F, Remy-Jouet I, Mongardon N, et al
    Hypothermic Total Liquid Ventilation Is Highly Protective Through Cerebral Hemodynamic Preservation and Sepsis-Like Mitigation After Asphyxial Cardiac Arrest.
    Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  458. DECOUX A, Tian Y, DeLeon-Pennell KY, Nguyen NT, et al
    Plasma Glycoproteomics Reveals Sepsis Outcomes Linked to Distinct Proteins in Common Pathways.
    Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  459. QURAISHI SA, De Pascale G, Needleman JS, Nakazawa H, et al
    Effect of Cholecalciferol Supplementation on Vitamin D Status and Cathelicidin Levels in Sepsis: A Randomized, Placebo-Controlled Trial.
    Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  460. DONNELLY JP, Hohmann SF, Wang HE
    Unplanned Readmissions After Hospitalization for Severe Sepsis at Academic Medical Center-Affiliated Hospitals.
    Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  461. VAN ROESSEL S, van der Laan AM, de Pont AC
    What is the best heparin to treat sepsis with?
    Crit Care Med. 2015;43:e212-3.
    PubMed     Text format    


  462. FULLERTON JN
    Increased mortality in "cold sepsis": the result of a frozen immune response?
    Crit Care Med. 2015;43:1327-9.
    PubMed     Text format    


  463. ZARYCHANSKI R, Kumar A
    The authors reply.
    Crit Care Med. 2015;43:e213.
    PubMed     Text format    


    May 2015
  464. VINCENT JL, Marshall JC, Dellinger RP, Simonson SG, et al
    Talactoferrin in Severe Sepsis: Results From the Phase II/III Oral tAlactoferrin in Severe sepsIS Trial.
    Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  465. RHEE C, Murphy MV, Li L, Platt R, et al
    Lactate Testing in Suspected Sepsis: Trends and Predictors of Failure to Measure Levels.
    Crit Care Med. 2015.
    PubMed     Text format     Abstract available


  466. RAGHUNATHAN K, Konoske R
    The authors reply.
    Crit Care Med. 2015;43:e156.
    PubMed     Text format    


  467. WEI H, Cao X, Zeng Q, Zhang F, et al
    Ghrelin inhibits proinflammatory responses and prevents cognitive impairment in septic rats.
    Crit Care Med. 2015;43:e143-50.
    PubMed     Text format     Abstract available


  468. SJODING MW, Iwashyna TJ, Dimick JB, Cooke CR, et al
    Gaming hospital-level pneumonia 30-day mortality and readmission measures by legitimate changes to diagnostic coding.
    Crit Care Med. 2015;43:989-95.
    PubMed     Text format     Abstract available


  469. HARRON K, Parslow R, Mok Q, Tibby SM, et al
    Monitoring quality of care through linkage of administrative data: national trends in bloodstream infection in U.K. PICUs 2003-2012.
    Crit Care Med. 2015;43:1070-8.
    PubMed     Text format     Abstract available


  470. LAGU T, Lindenauer P
    Can we make performance measures more resilient to the effects of coding?
    Crit Care Med. 2015;43:1141-3.
    PubMed     Text format    


  471. PUSKARICH MA, Sterling SA
    Decompensation to shock: what is the risk?
    Crit Care Med. 2015;43:1139-40.
    PubMed     Text format    


    April 2015
  472. BUCHMAN TG
    You tell me.
    Crit Care Med. 2015;43:727-8.
    PubMed     Text format    


  473. RAFFRAY L, Douchet I, Augusto JF, Youssef J, et al
    Septic shock sera containing circulating histones induce dendritic cell-regulated necrosis in fatal septic shock patients.
    Crit Care Med. 2015;43:e107-16.
    PubMed     Text format     Abstract available


  474. JESCHKE MG, Pinto R, Kraft R, Nathens AB, et al
    Morbidity and survival probability in burn patients in modern burn care.
    Crit Care Med. 2015;43:808-15.
    PubMed     Text format     Abstract available


  475. ORTEGO A, Gaieski DF, Fuchs BD, Jones T, et al
    Hospital-based acute care use in survivors of septic shock.
    Crit Care Med. 2015;43:729-37.
    PubMed     Text format     Abstract available


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