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Amedeo Prize 2008
The 21 Finalists


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Articles published in Crit Care Med

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Single Articles


    May 2008
  1. CHRIST-CRAIN M , Muller B
    Calcitonin peptides--the mediators in sepsis or just another fairy tale?
    Crit Care Med. 2008;36:1684-7.
    PubMed     Related articles   


  2. ALSTON TA
    Teasing and skinning muscles in sepsis research.
    Crit Care Med. 2008;36:1674-5.
    PubMed     Related articles   


  3. GORDON A , Knight JC, Hinds CJ
    Genes and sepsis: how tight is the fit?
    Crit Care Med. 2008;36:1652-4.
    PubMed     Related articles   


    April 2008
  4. ZAKARIAH AN , Cozzi SM, Nuffelen MV, Clausi CM, et al
    Combination of biphasic transmittance waveform with blood procalcitonin levels for diagnosis of sepsis in acutely ill patients.
    Crit Care Med. 2008;.
    PubMed     Related articles    Abstract available


  5. SEXTON PM , Christopoulos G, Christopoulos A, Nylen ES, et al
    Procalcitonin has bioactivity at calcitonin receptor family complexes: Potential mediator implications in sepsis*
    Crit Care Med. 2008;.
    PubMed     Related articles    Abstract available


  6. ZINK W , Kaess M, Hofer S, Plachky J, et al
    Alterations in intracellular Ca2+-homeostasis of skeletal muscle fibers during sepsis.
    Crit Care Med. 2008;.
    PubMed     Related articles    Abstract available


  7. MENGES T , Konig IR, Hossain H, Little S, et al
    Sepsis syndrome and death in trauma patients are associated with variation in the gene encoding tumor necrosis factor*
    Crit Care Med. 2008;.
    PubMed     Related articles    Abstract available


  8. LANGE M , Hamahata A, Enkhbaatar P, Esechie A, et al
    Assessment of vascular permeability in an ovine model of acute lung injury and pneumonia-induced Pseudomonas aeruginosa sepsis.
    Crit Care Med. 2008;36:1284-9.
    PubMed     Related articles    Abstract available


  9. TALMOR D , Greenberg D, Howell MD, Lisbon A, et al
    The costs and cost-effectiveness of an integrated sepsis treatment protocol.
    Crit Care Med. 2008;36:1168-74.
    PubMed     Related articles    Abstract available


  10. TANG BM , McLean AS, Dawes IW, Huang SJ, et al
    Gene-expression profiling of gram-positive and gram-negative sepsis in critically ill patients.
    Crit Care Med. 2008;36:1125-8.
    PubMed     Related articles    Abstract available


  11. WAN L , Bagshaw SM, Langenberg C, Saotome T, et al
    Pathophysiology of septic acute kidney injury: what do we really know?
    Crit Care Med. 2008;36.
    PubMed     Related articles    Abstract available


  12. TENHUNEN JJ
    Bull's eye missed by the magic bullet: preclinical investigations, publication bias, and promising new interventions.
    Crit Care Med. 2008;36:1361-3.
    PubMed     Related articles   


  13. WHEELER DS , Devarajan P, Ma Q, Harmon K, et al
    Serum neutrophil gelatinase-associated lipocalin (NGAL) as a marker of acute kidney injury in critically ill children with septic shock.
    Crit Care Med. 2008;36:1297-303.
    PubMed     Related articles    Abstract available


  14. HOPKINS PA , Pridmore AC, Ellmerich S, Fraser JD, et al
    Increased surface toll-like receptor 2 expression in superantigen shock.
    Crit Care Med. 2008;36:1267-76.
    PubMed     Related articles    Abstract available


  15. AMOUR J , Birenbaum A, Langeron O, Le Manach Y, et al
    Influence of renal dysfunction on the accuracy of procalcitonin for the diagnosis of postoperative infection after vascular surgery.
    Crit Care Med. 2008;36:1147-54.
    PubMed     Related articles    Abstract available


  16. SU J , Li X, Cui X, Li Y, et al
    Ethyl pyruvate decreased early nuclear factor-kappaB levels but worsened survival in lipopolysaccharide-challenged mice.
    Crit Care Med. 2008;36:1059-67.
    PubMed     Related articles    Abstract available


    March 2008
  17. DORRESTEIJN MJ , van der Hoeven HG, Pickkers P
    Volume therapy and innate immune response during systemic inflammation or sepsis.
    Crit Care Med. 2008;36:1028.
    PubMed     Related articles   


  18. RIVERS EP
    Volume therapy and innate immune response during systemic inflammation or sepsis.
    Crit Care Med. 2008;36:1028-9.
    PubMed     Related articles   


  19. CHEATHAM ML
    Resuscitation end points in severe sepsis: Central venous pressure, mean arterial pressure, mixed venous oxygen saturation, and ... intra-abdominal pressure.
    Crit Care Med. 2008;36:1012-4.
    PubMed     Related articles   


  20. COHEN RI
    Sepsis-induced left ventricular diastolic dysfunction: Little time to relax.
    Crit Care Med. 2008;36:999-1000.
    PubMed     Related articles   


  21. CARLET J , Cohen J, Calandra T, Opal SM, et al
    Sepsis: time to reconsider the concept.
    Crit Care Med. 2008;36:964-6.
    PubMed     Related articles    Abstract available


  22. BECKER KL , Snider R, Nylen ES
    Procalcitonin assay in systemic inflammation, infection, and sepsis: Clinical utility and limitations.
    Crit Care Med. 2008;36:941-52.
    PubMed     Related articles    Abstract available


  23. LIN SM , Wang YM, Lin HC, Lee KY, et al
    Serum thrombomodulin level relates to the clinical course of disseminated intravascular coagulation, multiorgan dysfunction syndrome, and mortality in patients with sepsis.
    Crit Care Med. 2008;36:683-9.
    PubMed     Related articles    Abstract available


    February 2008
  24. ROSSI MA , Celes MR
    Intercellular junctions in sepsis.
    Crit Care Med. 2008;36:660-661.
    PubMed     Related articles   


  25. SIRACUSANO L , Girasole V
    Intercellular junctions in sepsis.
    Crit Care Med. 2008;36:659-60.
    PubMed     Related articles   


  26. TOLEDO-PEREYRA LH
    Critical role of p38 mitogen protein kinase in sepsis.
    Crit Care Med. 2008;36:636-7.
    PubMed     Related articles   


  27. FODALE V , Santamaria LB
    Cholinesterase inhibitors improve survival in experimental sepsis: a new way to activate the cholinergic anti-inflammatory pathway.
    Crit Care Med. 2008;36:622-3.
    PubMed     Related articles   


  28. LORENTE L , Mora ML, Jimenez A
    Microorganisms responsible for femoral catheter-related bloodstream infection.
    Crit Care Med. 2008;36:657-8.
    PubMed     Related articles   


  29. FORCEVILLE X
    The need for precise dose information of sodium selenite in the SIC study and rectification of GPx-3 plasma concentration.
    Crit Care Med. 2008;36:656-7.
    PubMed     Related articles   


  30. BAUMGART K , Radermacher P, Calzia E, Hauser B, et al
    Pathophysiology of tissue acidosis in septic shock: blocked microcirculation or impaired cellular respiration?
    Crit Care Med. 2008;36:640-2.
    PubMed     Related articles   


  31. SCHULTZ MJ , Juffermans NP
    Maldistribution of interalveolar perfusion--one early step in the pathogenesis of lung injury?
    Crit Care Med. 2008;36:639-40.
    PubMed     Related articles   


  32. LEVERVE XM
    To cope with oxygen: a long and still tumultuous story for life.
    Crit Care Med. 2008;36:637-8.
    PubMed     Related articles   


  33. MERMEL LA
    Arterial catheters are not risk-free spigots.
    Crit Care Med. 2008;36:620-2.
    PubMed     Related articles   


  34. KEENE AB
    Thrombosis in central catheter-associated Staphylococcus aureus bacteremia: always scan the site?
    Crit Care Med. 2008;36:618-9.
    PubMed     Related articles   


  35. BUYSSE CM , Raat H, Hazelzet JA, Hop WC, et al
    Surviving meningococcal septic shock: health consequences and quality of life in children and their parents up to 2 years after pediatric intensive care unit discharge.
    Crit Care Med. 2008;36:596-602.
    PubMed     Related articles    Abstract available


  36. MURCH O , Abdelrahman M, Collino M, Gallicchio M, et al
    Sphingosylphosphorylcholine reduces the organ injury/dysfunction and inflammation caused by endotoxemia in the rat.
    Crit Care Med. 2008;36:550-9.
    PubMed     Related articles    Abstract available


  37. DUBIN A , Edul VS, Pozo MO, Murias G, et al
    Persistent villi hypoperfusion explains intramucosal acidosis in sheep endotoxemia.
    Crit Care Med. 2008;36:535-42.
    PubMed     Related articles    Abstract available


  38. STEPHENS DP , Thomas JH, Higgins A, Bailey M, et al
    Randomized, double-blind, placebo-controlled trial of granulocyte colony-stimulating factor in patients with septic shock.
    Crit Care Med. 2008;36:448-54.
    PubMed     Related articles    Abstract available


  39. KOH DB , Gowardman JR, Rickard CM, Robertson IK, et al
    Prospective study of peripheral arterial catheter infection and comparison with concurrently sited central venous catheters.
    Crit Care Med. 2008;36:397-402.
    PubMed     Related articles    Abstract available


  40. QUARTIN AA , Calonge RO, Schein RM, Crandall LA, et al
    Influence of critical illness on physicians' prognoses for underlying disease: a randomized study using simulated cases.
    Crit Care Med. 2008;36:462-70.
    PubMed     Related articles    Abstract available


  41. BARTH E , Bassi G, Maybauer DM, Simon F, et al
    Effects of ventilation with 100% oxygen during early hyperdynamic porcine fecal peritonitis.
    Crit Care Med. 2008;36:495-503.
    PubMed     Related articles    Abstract available


  42. ASADUZZAMAN M , Wang Y, Thorlacius H
    Critical role of p38 mitogen-activated protein kinase signaling in septic lung injury.
    Crit Care Med. 2008;36:482-8.
    PubMed     Related articles    Abstract available


  43. CROWLEY AL , Peterson GE, Benjamin DK Jr, Rimmer SH, et al
    Venous thrombosis in patients with short- and long-term central venous catheter-associated Staphylococcus aureus bacteremia.
    Crit Care Med. 2008;36:385-90.
    PubMed     Related articles    Abstract available


    January 2008
  44. PREISER JC , De Backer D
    Novel insights into the effects of inducible nitric oxide synthase inhibition during sepsis.
    Crit Care Med. 2008;36:359-60.
    PubMed     Related articles   


  45. WADA H , Hatada T
    Pathophysiology and diagnostic criteria for disseminated intravascular coagulation associated with sepsis.
    Crit Care Med. 2008;36:348-9.
    PubMed     Related articles   


  46. DELLINGER RP , Levy MM, Carlet JM, Bion J, et al
    Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008.
    Crit Care Med. 2008;36:296-327.
    PubMed     Related articles    Abstract available


  47. WHEELER A , Steingrub J, Schmidt GA, Sanchez P, et al
    A retrospective observational study of drotrecogin alfa (activated) in adults with severe sepsis: Comparison with a controlled clinical trial.
    Crit Care Med. 2008;36:14-23.
    PubMed     Related articles    Abstract available


  48. DOIG G
    Effectiveness of drotrecogin alfa (activated) in clinical practice: a stitch in time.
    Crit Care Med. 2008;36:332-3.
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  49. GHISELLI R , Giacometti A, Cirioni O, Mocchegiani F, et al
    Efficacy of the bovine antimicrobial peptide indolicidin combined with piperacillin/tazobactam in experimental rat models of polymicrobial peritonitis.
    Crit Care Med. 2008;36:240-5.
    PubMed     Related articles    Abstract available


  50. MAYR FB , Spiel AO, Leitner JM, Firbas C, et al
    Duffy antigen modifies the chemokine response in human endotoxemia.
    Crit Care Med. 2008;36:159-65.
    PubMed     Related articles    Abstract available


  51. OMLAND T
    Advances in congestive heart failure management in the intensive care unit: B-type natriuretic peptides in evaluation of acute heart failure.
    Crit Care Med. 2008;36.
    PubMed     Related articles    Abstract available


    December 2007
  52. SANKOFF JD , Goyal M, Gaieski DF, Dietch K, et al
    Validation of the Mortality in Emergency Department Sepsis (MEDS) score in patients with the systemic inflammatory response syndrome (SIRS)*
    Crit Care Med. 2007;.
    PubMed     Related articles    Abstract available


  53. HOFER S , Eisenbach C, Lukic IK, Schneider L, et al
    Pharmacologic cholinesterase inhibition improves survival in experimental sepsis*
    Crit Care Med. 2007;.
    PubMed     Related articles    Abstract available


  54. CONHAIM RL , Watson KE, Spiegel CA, Dovi WF, et al
    Bacteremic sepsis disturbs alveolar perfusion distribution in the lungs of rats*
    Crit Care Med. 2007;.
    PubMed     Related articles    Abstract available


  55. BAUHOFER A , Torossian A
    Mechanical vagus nerve stimulation-A new adjunct in sepsis prophylaxis and treatment?
    Crit Care Med. 2007;35:2868-9.
    PubMed     Related articles   


  56. NEUGEBAUER EA
    To use or not to use? Polyclonal intravenous immunoglobulins for the treatment of sepsis and septic shock.
    Crit Care Med. 2007;35:2855-6.
    PubMed     Related articles   


  57. FIDAN H , Sahin O, Yavuz Y, Kilbas A, et al
    Caffeic acid phenethyl ester reduces mortality and sepsis-induced lung injury in rats.
    Crit Care Med. 2007;35:2822-9.
    PubMed     Related articles    Abstract available


  58. BELIKOVA I , Lukaszewicz AC, Faivre V, Damoisel C, et al
    Oxygen consumption of human peripheral blood mononuclear cells in severe human sepsis.
    Crit Care Med. 2007;35:2702-8.
    PubMed     Related articles    Abstract available


  59. WERDAN K , Pilz G, Bujdoso O, Fraunberger P, et al
    Score-based immunoglobulin G therapy of patients with sepsis: the SBITS study.
    Crit Care Med. 2007;35:2693-2701.
    PubMed     Related articles    Abstract available


  60. LAUPLAND KB , Kirkpatrick AW, Delaney A
    Polyclonal intravenous immunoglobulin for the treatment of severe sepsis and septic shock in critically ill adults: a systematic review and meta-analysis.
    Crit Care Med. 2007;35:2686-92.
    PubMed     Related articles    Abstract available


  61. KREYMANN KG , de Heer G, Nierhaus A, Kluge S, et al
    Use of polyclonal immunoglobulins as adjunctive therapy for sepsis or septic shock.
    Crit Care Med. 2007;35:2677-85.
    PubMed     Related articles    Abstract available


  62. EICHACKER PQ , Natanson C, Danner RL
    Separating practice guidelines from pharmaceutical marketing.
    Crit Care Med. 2007;35:2877-8.
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  63. CROUSER ED
    Suppression of monocyte metabolism by septic plasma: revisiting the concept of "blood poisoning".
    Crit Care Med. 2007;35:2856-7.
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  64. WERDAN K
    Mirror, mirror on the wall, which is the fairest meta-analysis of all?
    Crit Care Med. 2007;35:2852-4.
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  65. VAN ZOELEN MA , Laterre PF, van Veen SQ, van Till JW, et al
    Systemic and local high mobility group box 1 concentrations during severe infection.
    Crit Care Med. 2007;35:2799-804.
    PubMed     Related articles    Abstract available


  66. KOCH A , Boehm O, Zacharowski PA, Loer SA, et al
    Inducible nitric oxide synthase and heme oxygenase-1 in the lung during lipopolysaccharide tolerance and cross tolerance.
    Crit Care Med. 2007;35:2775-84.
    PubMed     Related articles    Abstract available


    November 2007
  67. BEALE RJ , Sherry T, Lei K, Campbell-Stephen L, et al
    Early enteral supplementation with key pharmaconutrients improves Sequential Organ Failure Assessment score in critically ill patients with sepsis: Outcome of a randomized, controlled, double-blind trial.
    Crit Care Med. 2007;.
    PubMed     Related articles    Abstract available


  68. BROMBERG Z , Raj N, Goloubinoff P, Deutschman CS, et al
    Enhanced expression of 70-kilodalton heat shock protein limits cell division in a sepsis-induced model of acute respiratory distress syndrome*
    Crit Care Med. 2007;.
    PubMed     Related articles    Abstract available


  69. RANJAN D
    Industry support and sepsis guidelines.
    Crit Care Med. 2007;35:2665.
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  70. DURBIN CG JR
    Industry support and sepsis guidelines.
    Crit Care Med. 2007;35:2665-2666.
    PubMed     Related articles   


  71. CORNET AD , Beishuizen A, Groeneveld AB
    Activated protein C in sepsis: Tightening pulmonary endothelial cells?
    Crit Care Med. 2007;35:2656-2658.
    PubMed     Related articles   


  72. CRIBBS SK , Martin GS
    Expanding the global epidemiology of sepsis.
    Crit Care Med. 2007;35:2646-2648.
    PubMed     Related articles   


  73. CARLSON DE , Chiu WC, Johnson SB, Scalea TM, et al
    Barriers to the optimal resuscitation of patients with severe sepsis? Transfer to a level I critical care center!
    Crit Care Med. 2007;35:2644-2645.
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  74. CARLBOM DJ , Rubenfeld GD
    Barriers to implementing protocol-based sepsis resuscitation in the emergency department-Results of a national survey.
    Crit Care Med. 2007;35:2525-2532.
    PubMed     Related articles    Abstract available


  75. WANG Z , Su F, Rogiers P, Vincent JL, et al
    Beneficial effects of recombinant human activated protein C in a ewe model of septic shock.
    Crit Care Med. 2007;35:2594-600.
    PubMed     Related articles    Abstract available


    October 2007
  76. KREYMANN KG , de Heer G, Nierhaus A, Kluge S, et al
    Use of polyclonal immunoglobulins as adjunctive therapy for sepsis or septic shock*
    Crit Care Med. 2007;.
    PubMed     Related articles    Abstract available


  77. WERDAN K , Pilz G, Bujdoso O, Fraunberger P, et al
    Score-based immunoglobulin G therapy of patients with sepsis: The SBITS study*
    Crit Care Med. 2007;.
    PubMed     Related articles    Abstract available


  78. LAUPLAND KB , Kirkpatrick AW, Delaney A
    Polyclonal intravenous immunoglobulin for the treatment of severe sepsis and septic shock in critically ill adults: A systematic review and meta-analysis*
    Crit Care Med. 2007;.
    PubMed     Related articles    Abstract available


  79. PHILLIPS CR , Chesnutt MS, Smith SM
    Extravascular lung water in sepsis-associated acute respiratory distress syndrome: Indexing with predicted body weight improves correlation with severity of illness and survival*
    Crit Care Med. 2007;.
    PubMed     Related articles    Abstract available


  80. FIDAN H , Sahin O, Yavuz Y, Kilbas A, et al
    Caffeic acid phenethyl ester reduces mortality and sepsis-induced lung injury in rats*
    Crit Care Med. 2007;.
    PubMed     Related articles    Abstract available


  81. BATEMAN RM , Sharpe MD, Goldman D, Lidington D, et al
    Inhibiting nitric oxide overproduction during hypotensive sepsis increases local oxygen consumption in rat skeletal muscle*
    Crit Care Med. 2007;.
    PubMed     Related articles    Abstract available


  82. BELIKOVA I , Lukaszewicz AC, Ass VF, Damoisel C, et al
    Oxygen consumption of human peripheral blood mononuclear cells in severe human sepsis*
    Crit Care Med. 2007;.
    PubMed     Related articles    Abstract available


  83. SAKR Y , Vincent JL, De Backer D
    Does red blood cell transfusion result in a variate microvascular response in sepsis?
    Crit Care Med. 2007;35:2465.
    PubMed     Related articles   


  84. TANG BM , Huang SJ, Seppelt I, McLean AS, et al
    Predictive value of N-terminal pro-brain natriuretic peptide in sepsis.
    Crit Care Med. 2007;35:2464.
    PubMed     Related articles   


  85. DEN UIL CA , Lagrand WK, Spronk PE, Simoons ML, et al
    Does red blood cell transfusion result in a variate microvascular response in sepsis?
    Crit Care Med. 2007;35:2464-2465.
    PubMed     Related articles   


  86. DELLINGER RP , Schorr C
    Severe sepsis in an emergency department: Prevalence, rapid identification, and appropriate treatment.
    Crit Care Med. 2007;35:2461-2.
    PubMed     Related articles   


  87. LEVY B , Lacolley P, Regnault V
    ADAMTS-13 (A disintegrin-like and metalloprotease with thrombospondin) and endothelial dysfunction in sepsis: Marker or culprit?
    Crit Care Med. 2007;35:2453-4.
    PubMed     Related articles   


  88. BOWLER R , Reisdorph N
    Mining the liver proteome for drug targets for sepsis.
    Crit Care Med. 2007;35:2443-4.
    PubMed     Related articles   


  89. LOMAS-NEIRA JL , Ayala A
    CXCL2 polymorphism in sepsis and acute respiratory distress syndrome: Pathological significance lost in translation.
    Crit Care Med. 2007;35:2439-40.
    PubMed     Related articles   


  90. ABRAHAM E , Singer M
    Mechanisms of sepsis-induced organ dysfunction.
    Crit Care Med. 2007;35:2408-16.
    PubMed     Related articles    Abstract available


  91. HOTTA N , Ichiyama T, Shiraishi M, Takekawa T, et al
    Nuclear factor-kappaB activation in peripheral blood mononuclear cells in children with sepsis.
    Crit Care Med. 2007;35:2395-401.
    PubMed     Related articles    Abstract available


  92. MARTIN K , Borgel D, Lerolle N, Feys HB, et al
    Decreased ADAMTS-13 (A disintegrin-like and metalloprotease with thrombospondin type 1 repeats) is associated with a poor prognosis in sepsis-induced organ failure.
    Crit Care Med. 2007;35:2375-82.
    PubMed     Related articles    Abstract available


  93. KIANK C , Koerner P, Kessler W, Traeger T, et al
    Seasonal variations in inflammatory responses to sepsis and stress in mice.
    Crit Care Med. 2007;35:2352-8.
    PubMed     Related articles    Abstract available


  94. BARRETT LK , Orie NN, Taylor V, Stidwill RP, et al
    Differential effects of vasopressin and norepinephrine on vascular reactivity in a long-term rodent model of sepsis.
    Crit Care Med. 2007;35:2337-43.
    PubMed     Related articles    Abstract available


  95. DEAR JW , Leelahavanichkul A, Aponte A, Hu X, et al
    Liver proteomics for therapeutic drug discovery: inhibition of the cyclophilin receptor CD147 attenuates sepsis-induced acute renal failure.
    Crit Care Med. 2007;35:2319-28.
    PubMed     Related articles    Abstract available


  96. VILLAR J , Perez-Mendez L, Flores C, Maca-Meyer N, et al
    A CXCL2 polymorphism is associated with better outcomes in patients with severe sepsis.
    Crit Care Med. 2007;35:2292-7.
    PubMed     Related articles    Abstract available


  97. MORIMATSU H
    Stewart has come to the bedside: is it time to use the Stewart methodology routinely?
    Crit Care Med. 2007;35:2456-7.
    PubMed     Related articles   


  98. VAN WESTERLOO DJ
    Summertime and the living is easy.
    Crit Care Med. 2007;35:2450-1.
    PubMed     Related articles   


  99. MORELLI A , Ertmer C, Westphal M
    Ten years of vasopressin research in septic shock: constant dripping wears the stone.
    Crit Care Med. 2007;35:2447-8.
    PubMed     Related articles   


  100. LORENTE L , Jimenez A, Santana M, Iribarren JL, et al
    Microorganisms responsible for intravascular catheter-related bloodstream infection according to the catheter site.
    Crit Care Med. 2007;35:2424-7.
    PubMed     Related articles    Abstract available


    September 2007
  101. HUSTON JM , Puerta MG, Ochani M, Ochani K, et al
    Transcutaneous vagus nerve stimulation reduces serum high mobility group box 1 levels and improves survival in murine sepsis*
    Crit Care Med. 2007;.
    PubMed     Related articles    Abstract available


  102. CHENG B , Xie G, Yao S, Wu X, et al
    Epidemiology of severe sepsis in critically ill surgical patients in ten university hospitals in China*
    Crit Care Med. 2007;.
    PubMed     Related articles    Abstract available


  103. HOPKINS RO
    Sepsis, oxidative stress, and brain injury.
    Crit Care Med. 2007;35:2233-4.
    PubMed     Related articles   


  104. SPRAY DC , Tanowitz HB
    Pathology of mechanical and gap junctional co-coupling at the intercalated disc: Is sepsis a junctionopathy?
    Crit Care Med. 2007;35:2231-2.
    PubMed     Related articles   


  105. ANDERSON RJ
    Kidney in sepsis.
    Crit Care Med. 2007;35:2223-4.
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  106. TRZECIAK S , De Backer D
    Modulation of the sepsis inflammatory response by resuscitation: The missing link between cytopathic and hypoxic hypoxia?
    Crit Care Med. 2007;35:2206-7.
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  107. BARICHELLO T , Machado RA, Constantino L, Valvassori SS, et al
    Antioxidant treatment prevented late memory impairment in an animal model of sepsis.
    Crit Care Med. 2007;35:2186-90.
    PubMed     Related articles    Abstract available


  108. CELES MR , Torres-Duenas D, Alves-Filho JC, Duarte DB, et al
    Reduction of gap and adherens junction proteins and intercalated disc structural remodeling in the hearts of mice submitted to severe cecal ligation and puncture sepsis.
    Crit Care Med. 2007;35:2176-85.
    PubMed     Related articles    Abstract available


  109. SCHMIDT C , Hocherl K, Schweda F, Bucher M, et al
    Proinflammatory cytokines cause down-regulation of renal chloride entry pathways during sepsis.
    Crit Care Med. 2007;35:2110-9.
    PubMed     Related articles    Abstract available


  110. HUANG DT , Clermont G, Dremsizov TT, Angus DC, et al
    Implementation of early goal-directed therapy for severe sepsis and septic shock: A decision analysis.
    Crit Care Med. 2007;35:2090-100.
    PubMed     Related articles    Abstract available


  111. RIVERS EP , Kruse JA, Jacobsen G, Shah K, et al
    The influence of early hemodynamic optimization on biomarker patterns of severe sepsis and septic shock.
    Crit Care Med. 2007;35:2016-24.
    PubMed     Related articles    Abstract available


  112. HSIEH YC , Frink M, Choudhry MA, Bland KI, et al
    Metabolic modulators following trauma sepsis: sex hormones.
    Crit Care Med. 2007;35.
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  113. NORBURY WB , Jeschke MG, Herndon DN
    Metabolism modulators in sepsis: propranolol.
    Crit Care Med. 2007;35.
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  114. MAXIME V , Siami S, Annane D
    Metabolism modulators in sepsis: the abnormal pituitary response.
    Crit Care Med. 2007;35.
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  115. BIOLO G , Antonione R, De Cicco M
    Glutathione metabolism in sepsis.
    Crit Care Med. 2007;35.
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  116. BERGER MM , Chiolero RL
    Antioxidant supplementation in sepsis and systemic inflammatory response syndrome.
    Crit Care Med. 2007;35.
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  117. BARBUL A , Uliyargoli A
    Use of exogenous arginine in multiple organ dysfunction syndrome and sepsis.
    Crit Care Med. 2007;35.
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  118. LUIKING YC , Deutz NE
    Exogenous arginine in sepsis.
    Crit Care Med. 2007;35.
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  119. TAPPY L , Chiolero R
    Substrate utilization in sepsis and multiple organ failure.
    Crit Care Med. 2007;35.
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  120. LEVY RJ , Deutschman CS
    Cytochrome c oxidase dysfunction in sepsis.
    Crit Care Med. 2007;35.
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    Mitochondrial function in sepsis: respiratory versus leg muscle.
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  122. SINGER M
    Mitochondrial function in sepsis: acute phase versus multiple organ failure.
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  123. VINCENT JL
    Metabolic support in sepsis and multiple organ failure: more questions than answers ...
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  124. HERNDON DN , Wernerman J
    Metabolic support in sepsis and multiple organ failure.
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  125. PROTTI A , Carre J, Frost MT, Taylor V, et al
    Succinate recovers mitochondrial oxygen consumption in septic rat skeletal muscle.
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  126. PIEL DA , Gruber PJ, Weinheimer CJ, Courtois MR, et al
    Mitochondrial resuscitation with exogenous cytochrome c in the septic heart.
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  127. DE JONGHE B , Bastuji-Garin S, Durand MC, Malissin I, et al
    Respiratory weakness is associated with limb weakness and delayed weaning in critical illness.
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  128. WHEELER DS
    Understanding the role of stress proteins in acute lung injury: Closer to the answer, but not there yet.
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  129. FINK MP
    Administration of exogenous cytochrome c as a novel approach for the treatment of cytopathic hypoxia.
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  130. SCHULTZ MJ , Spronk PE
    Positive blood cultures or Gram-negative pathogens with ventilator-associated pneumonia: What's the real killer?
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  131. AGBAHT K , Diaz E, Munoz E, Lisboa T, et al
    Bacteremia in patients with ventilator-associated pneumonia is associated with increased mortality: A study comparing bacteremic vs. nonbacteremic ventilator-associated pneumonia.
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  133. RUSSELL JA
    Vasopressin in septic shock.
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  134. BIESALSKI HK , McGregor GP
    Antioxidant therapy in critical care--is the microcirculation the primary target?
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  135. TJADER I , Berg A, Wernerman J
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  136. BONGERS T , Griffiths RD, McArdle A
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  137. YASUHARA S , Asai A, Sahani ND, Martyn JA, et al
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    August 2007
  139. O'DELL E , Tibby SM, Durward A, Murdoch IA, et al
    Hyperchloremia is the dominant cause of metabolic acidosis in the postresuscitation phase of pediatric meningococcal sepsis*
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  140. CARLBOM DJ , Rubenfeld GD
    Barriers to implementing protocol-based sepsis resuscitation in the emergency department-Results of a national survey*
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  141. DEAR JW , Leelahavanichkul A, Aponte A, Hu X, et al
    Liver proteomics for therapeutic drug discovery: Inhibition of the cyclophilin receptor CD147 attenuates sepsis-induced acute renal failure*
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  142. HOTTA N , Ichiyama T, Shiraishi M, Takekawa T, et al
    Nuclear factor-kappaB activation in peripheral blood mononuclear cells in children with sepsis*
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  143. VILLAR J , Perez-Mendez L, Flores C, Maca-Meyer N, et al
    A CXCL2 polymorphism is associated with better outcomes in patients with severe sepsis*
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  144. BARRETT LK , Orie NN, Taylor V, Stidwill RP, et al
    Differential effects of vasopressin and norepinephrine on vascular reactivity in a long-term rodent model of sepsis*
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  145. ABRAHAM E , Singer M
    Mechanisms of sepsis-induced organ dysfunction.
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  146. KIANK C , Koerner P, Keler W, Traeger T, et al
    Seasonal variations in inflammatory responses to sepsis and stress in mice*
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  147. MARTIN K , Borgel D, Lerolle N, Feys HB, et al
    Decreased a disintegrin-like and metalloprotease with thrombospondin (ADAMTS)-13 is associated with a poor prognosis in sepsis-induced organ failure*
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    Are we finally taming inflammation?
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  149. GAFFIN SL
    A pathophysiology-based approach to care of nuclear explosion victims.
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  150. KNOEBL PN
    Is there an association between hemostatic abnormalities and the outcome of acute lung injury?
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  151. GARNACHO-MONTERO J , Sa-Borges M, Sole-Violan J, Barcenilla F, et al
    Optimal management therapy for Pseudomonas aeruginosa ventilator-associated pneumonia: an observational, multicenter study comparing monotherapy with combination antibiotic therapy.
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  152. MONNERET G , Voirin N, Krawice-Radanne I, Bohe J, et al
    Soluble human leukocyte antigen-G5 in septic shock: marked and persisting elevation as a predictor of survival.
    Crit Care Med. 2007;35:1942-7.
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  153. VENET F , Tissot S, Debard AL, Faudot C, et al
    Decreased monocyte human leukocyte antigen-DR expression after severe burn injury: Correlation with severity and secondary septic shock.
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  154. DE JONG MF , Beishuizen A, Spijkstra JJ, Groeneveld AB, et al
    Relative adrenal insufficiency as a predictor of disease severity, mortality, and beneficial effects of corticosteroid treatment in septic shock.
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  155. SCHALLER G , Pleiner J, Mittermayer F, Posch M, et al
    Effects of N-acetylcysteine against systemic and renal hemodynamic effects of endotoxin in healthy humans.
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    July 2007
  156. RIVERS EP , Kruse JA, Jacobsen G, Shah K, et al
    The influence of early hemodynamic optimization on biomarker patterns of severe sepsis and septic shock*
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  157. SCHMIDT C , Hocherl K, Schweda F, Bucher M, et al
    Proinflammatory cytokines cause down-regulation of renal chloride entry pathways during sepsis*
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  158. BARICHELLO T , Machado RA, Constantino L, Valvassori SS, et al
    Antioxidant treatment prevented late memory impairment in an animal model of sepsis*
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  159. CELES MR , Torres-Duenas D, Alves-Filho JC, Duarte DB, et al
    Reduction of gap and adherens junction proteins and intercalated disc structural remodeling in the hearts of mice submitted to severe cecal ligation and puncture sepsis*
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  160. HUANG DT , Clermont G, Dremsizov TT, Angus DC, et al
    Implementation of early goal-directed therapy for severe sepsis and septic shock: A decision analysis.
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  161. MCLEAN AS , Huang SJ
    Prognostic value of natriuretic peptides in severe sepsis.
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  162. BRUECKMANN M , Hoffmann U
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  163. FU SL , Bluth MH
    Monitoring efficacy of red blood cell transfusion in sepsis by sublingual microvascular perfusion: A tongue speaks without words.
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  164. CHO SJ , Kanna B
    Selenium in intensive care: An interesting yet not fully proven concept.
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  165. ALLEVA LM
    Biologically active versus immunoreactive high-mobility group box 1.
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  168. PATERSON DL , Lipman J
    Returning to the pre-antibiotic era in the critically ill: the XDR problem.
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  169. SENNOUN N , Montemont C, Gibot S, Lacolley P, et al
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  170. RAFAT N , Hanusch C, Brinkkoetter PT, Schulte J, et al
    Increased circulating endothelial progenitor cells in septic patients: correlation with survival.
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  172. TSAO PN , Chan FT, Wei SC, Hsieh WS, et al
    Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis.
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  175. GARNACHO-MONTERO J , Ortiz-Leyba C
    Optimizing the treatment of a new horseman of the Apocalypse.
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  178. O'BRIEN JM
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  179. BAGSHAW SM , Langenberg C, Wan L, May CN, et al
    A systematic review of urinary findings in experimental septic acute renal failure.
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  180. VAN EIJK LT , Dorresteijn MJ, Smits P, van der Hoeven JG, et al
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  181. SHERER K , Li Y, Cui X, Li X, et al
    Fluid support worsens outcome and negates the benefit of protective antigen-directed monoclonal antibody in a lethal toxin-infused rat Bacillus anthracis shock model.
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    May 2007
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    Microvascular response to red blood cell transfusion in patients with severe sepsis*
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    Fluid therapy continues to be validated in early sepsis: Impact on myocardial depression.
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  184. HOWELL MD , Shapiro NI
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    Brain natriuretic peptides in sepsis: Ideal biomarker or just along for the ride?
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    Mannose binding lectin (MBL)-2 codon 54BB genotype associated with acute respiratory distress syndrome only by its association with bacterial infection.
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    A central venous pressure goal of 8-12 mm Hg for all patients in septic shock.
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  189. ZILBERBERG MD , Higgins TL
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  190. BARRAUD D , Faivre V, Damy T, Welschbillig S, et al
    Levosimendan restores both systolic and diastolic cardiac performance in lipopolysaccharide-treated rabbits: comparison with dobutamine and milrinone.
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  191. VISH MG , Mangeshkar P, Piraino G, Denenberg A, et al
    Proinsulin c-peptide exerts beneficial effects in endotoxic shock in mice.
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    Pre-B-cell colony-enhancing factor gene polymorphisms and risk of acute respiratory distress syndrome.
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  193. TOKUNAGA C , Bateman RM, Boyd J, Wang Y, et al
    Albumin resuscitation improves ventricular contractility and myocardial tissue oxygenation in rat endotoxemia.
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  194. DUBIN A , Menises MM, Masevicius FD, Moseinco MC, et al
    Comparison of three different methods of evaluation of metabolic acid-base disorders.
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    April 2007
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    Efficacy of colistin/rifampin combination in experimental rat models of sepsis due to a multiresistant Pseudomonas aeruginosa strain*
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  198. LATERRE PF , Abraham E, Janes JM, Trzaskoma BL, et al
    ADDRESS (ADministration of DRotrecogin alfa [activated] in Early stage Severe Sepsis long-term follow-up: One-year safety and efficacy evaluation*
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  199. SUNDEN-CULLBERG J , Nystrom T, Lee ML, Mullins GE, et al
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    Adoption of sepsis bundles in the emergency room and intensive care unit: A model for quality improvement.
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  201. WATERER GW
    High-mobility group box 1 (HMGB1) as a potential therapeutic target in sepsis--more questions than answers.
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  203. BOJALIL R
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  204. WEIL MH , Tang W
    Welcoming a new era of hemodynamic monitoring: expanding from the macro to the microcirculation.
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  205. GINSBERG F , Topalian S
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  206. SHORR AF , Lazarus DR, Sherner JH, Jackson WL, et al
    Do clinical features allow for accurate prediction of fungal pathogenesis in bloodstream infections? Potential implications of the increasing prevalence of non-albicans candidemia.
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    March 2007
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    Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: A trend analysis from 1993 to 2003*
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  208. VARPULA M , Pulkki K, Karlsson S, Ruokonen E, et al
    Predictive value of N-terminal pro-brain natriuretic peptide in severe sepsis and septic shock.
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  209. ESTEBAN A , Frutos-Vivar F, Ferguson ND, Penuelas O, et al
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  210. LEAVER SK , Finney SJ, Burke-Gaffney A, Evans TW, et al
    Sepsis since the discovery of Toll-like receptors: Disease concepts and therapeutic opportunities.
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  211. SHORR AF , Micek ST, Jackson WL Jr, Kollef MH, et al
    Economic implications of an evidence-based sepsis protocol: Can we improve outcomes and lower costs?*
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  212. ORTIZ-LEYBA C , Garnacho-Montero J
    Saving lives in severe sepsis with the help of enteral nutrition.
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  213. FERNANDES CJ
    Sepsis-induced myocardial depression: where is the missing link?
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  214. MESSARIS E
    Actin-binding plasma gelsolin: a potential future ally in the fight against sepsis.
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  215. BERKOWITZ DM , Martin GS
    Disparities in sepsis: what do we understand?
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  216. SCHOMBURG L
    Selenium in intensive care (SIC) study: the XX files are still unresolved.
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  217. PEAKE S , Webb S, Delaney A
    Early goal-directed therapy of septic shock: we honestly remain skeptical.
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  218. MULLER B , Gencay MM, Gibot S, Stolz D, et al
    Circulating levels of soluble triggering receptor expressed on myeloid cells (sTREM)-1 in community-acquired pneumonia.
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  219. CURTIS L
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  220. FILEP JG
    Septic plasma-induced oxidative stress in endothelial cells: a sensitive bioassay predicting outcome in septic shock?
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  221. HUET O , Obata R, Aubron C, Spraul-Davit A, et al
    Plasma-induced endothelial oxidative stress is related to the severity of septic shock.
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    Evaluating the management of septic shock using patient simulation.
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    February 2007
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    Implementation of a bundle of quality indicators for the early management of severe sepsis and septic shock is associated with decreased mortality*
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  224. MCLEAN AS , Huang SJ, Hyams S, Poh G, et al
    Prognostic values of B-type natriuretic peptide in severe sepsis and septic shock*
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  225. ANGUS DC , Yang L, Kong L, Kellum JA, et al
    Circulating high-mobility group box 1 (HMGB1) concentrations are elevated in both uncomplicated pneumonia and pneumonia with severe sepsis*
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  226. PAVLOV VA , Ochani M, Yang LH, Gallowitsch-Puerta M, et al
    Selective alpha7-nicotinic acetylcholine receptor agonist GTS-21 improves survival in murine endotoxemia and severe sepsis*
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