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  Tuberculosis

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Articles published in Antimicrob Agents Chemother

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Single Articles


    June 2017
  1. FOFANA MO, Dowdy DW
    Reply to Anthony et al., "Protecting Pyrazinamide, a Priority for Improving Outcomes in Multidrug-Resistant Tuberculosis Treatment".
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Text format    


  2. ANTHONY RM, Cynamon M, Hoffner S, Werngren J, et al
    Protecting Pyrazinamide, a Priority for Improving Outcomes in Multidrug-Resistant Tuberculosis Treatment.
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Text format    


    May 2017
  3. VAN'T BOVENEIND-VRUBLEUSKAYA N, Seuruk T, van Hateren K, van der Laan T, et al
    Pharmacokinetics of Levofloxacin in Multidrug- and Extensively Drug-Resistant Tuberculosis patients.
    Antimicrob Agents Chemother. 2017 May 15. pii: AAC.00343.
    PubMed     Text format     Abstract available


  4. SLOAN DJ, McCallum AD, Schipani A, Egan D, et al
    Genetic determinants of the pharmacokinetic variability of rifampicin in Malawian adults with pulmonary tuberculosis.
    Antimicrob Agents Chemother. 2017 May 1. pii: AAC.00210.
    PubMed     Text format     Abstract available


    April 2017
  5. NJIRE M, Wang N, Wang B, Tan Y, et al
    Pyrazinoic Acid Inhibits a Bifunctional Enzyme in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2017 Apr 24. pii: AAC.00070.
    PubMed     Text format     Abstract available


  6. VISWANATHAN G, Yadav S, Raghunand TR
    Identification of mycobacterial genes involved in antibiotic sensitivity - Implications in the treatment of tuberculosis with beta-lactam containing regimens.
    Antimicrob Agents Chemother. 2017 Apr 24. pii: AAC.00425.
    PubMed     Text format     Abstract available


  7. OLLIARO PL, Merle C, Mthiyane T, Bah B, et al
    Analysis of the effects on the QT interval of a gatifloxacin-containing regimen versus standard treatment of pulmonary tuberculosis.
    Antimicrob Agents Chemother. 2017 Apr 24. pii: AAC.01834.
    PubMed     Text format     Abstract available


  8. DANELISHVILI L, Shulzhenko N, Chinison JJJ, Babrak L, et al
    Mycobacterium tuberculosis proteome response to anti-tuberculosis compounds reveals metabolic "escape" pathways that prolong bacterial survival.
    Antimicrob Agents Chemother. 2017 Apr 17. pii: AAC.00430.
    PubMed     Text format     Abstract available


  9. JANG J, Kim R, Woo M, Jeong J, et al
    Efflux attenuates the anti-bacterial activity of Q203 in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2017 Apr 17. pii: AAC.02637.
    PubMed     Text format     Abstract available


  10. KEMPKER RR, Heinrichs MT, Nikolaishvili K, Sabulua I, et al
    Lung Tissue Concentrations of Pyrazinamide among Patients with Drug-Resistant Pulmonary Tuberculosis.
    Antimicrob Agents Chemother. 2017 Apr 3. pii: AAC.00226.
    PubMed     Text format     Abstract available


  11. CHEN X, Hashizume H, Tomishige T, Nakamura I, et al
    Delamanid Kills Dormant Mycobacteria in Vitro and in the Guinea Pig Model of Tuberculosis.
    Antimicrob Agents Chemother. 2017 Apr 3. pii: AAC.02402.
    PubMed     Text format     Abstract available


    March 2017
  12. XU J, Wang B, Hu M, Huo F, et al
    Primary clofazimine and bedaquiline resistance among isolates from patients with multidrug-resistant tuberculosis.
    Antimicrob Agents Chemother. 2017 Mar 20. pii: AAC.00239.
    PubMed     Text format     Abstract available


  13. ALSULTAN A, Savic R, Dooley KE, Weiner M, et al
    Population Pharmacokinetics of Pyrazinamide in Patients with Tuberculosis.
    Antimicrob Agents Chemother. 2017 Mar 13. pii: AAC.02625.
    PubMed     Text format     Abstract available


  14. VELASQUEZ GE, Calderon RI, Mitnick CD, Becerra MC, et al
    Erratum for Velasquez et al., Pyrazinamide Resistance Assays and Two-Month Sputum Culture Status in Patients with Multidrug-Resistant Tuberculosis.
    Antimicrob Agents Chemother. 2017;61.
    PubMed     Text format    


    February 2017
  15. RAMACHANDRAN G, Kumar AK, Chandrasekaran V, Kannan T, et al
    Factors influencing tuberculosis treatment outcome in adult patients treated with thrice-weekly regimens in India.
    Antimicrob Agents Chemother. 2017 Feb 27. pii: AAC.02464.
    PubMed     Text format     Abstract available


  16. KAYIGIRE XA, Friedrich SO, van der Merwe L, Diacon AH, et al
    Acquisition of rifampin resistance in pulmonary tuberculosis.
    Antimicrob Agents Chemother. 2017 Feb 6. pii: AAC.02220.
    PubMed     Text format     Abstract available


    January 2017
  17. AJILEYE A, Alvarez N, Merker M, Walker TM, et al
    Some synonymous and non-synonymous gyrA mutations in Mycobacterium tuberculosis lead to systematic false-resistance results to fluoroquinolones with the Hain GenoType MTBDRsl assays.
    Antimicrob Agents Chemother. 2017 Jan 30. pii: AAC.02169.
    PubMed     Text format     Abstract available


  18. DE JAGER V, van der Merwe L, Venter A, Donald PR, et al
    Time trends in sputum mycobacterial load and 2-day bactericidal activity of INH-containing anti-tuberculosis therapies.
    Antimicrob Agents Chemother. 2017 Jan 30. pii: AAC.02088.
    PubMed     Text format     Abstract available


  19. KUMAR P, Kaushik A, Bell D, Chauhan V, et al
    Mutation in an unannotated protein confers carbapenem resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2017 Jan 9. pii: AAC.02234.
    PubMed     Text format     Abstract available


  20. VAN ALTENA R, Dijkstra JA, van der Meer ME, Borjas Howard JF, et al
    Reduced chance of hearing loss associated with Therapeutic Drug Monitoring of Aminoglycosides in the treatment of Multidrug Resistant Tuberculosis.
    Antimicrob Agents Chemother. 2017 Jan 9. pii: AAC.01400.
    PubMed     Text format     Abstract available


  21. SCHUMP MD, Fox DM, Bertozzi CR, Riley LW, et al
    Subcellular Partitioning and Intra-Macrophage Selectivity of Antimicrobial Compounds Against Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2017 Jan 4. pii: AAC.01639.
    PubMed     Text format     Abstract available


    December 2016
  22. IACOBINO A, Piccaro G, Giannoni F, Mustazzolu A, et al
    Mycobacterium tuberculosis is selectively killed by rifampin and rifapentine in hypoxia at neutral pH.
    Antimicrob Agents Chemother. 2016 Dec 19. pii: AAC.02296.
    PubMed     Text format     Abstract available


  23. FOFANA MO, Shrestha S, Knight GM, Cohen T, et al
    Role of pyrazinamide in the emergence of extensively drug-resistant tuberculosis: a multi-strain mathematical model.
    Antimicrob Agents Chemother. 2016 Dec 12. pii: AAC.00498.
    PubMed     Text format     Abstract available


  24. PANG Y, Zhang Z, Wang Y, Wang S, et al
    Genotyping and prevalence of pyrazinamide- and moxifloxacin-resistant tuberculosis in China, 2000-2010: findings from the national survey data.
    Antimicrob Agents Chemother. 2016 Dec 5. pii: AAC.02170.
    PubMed     Text format     Abstract available


    November 2016
  25. BROSSIER F, Pham A, Bernard C, Aubry A, et al
    Molecular investigation of resistance to second line injectable drugs in multidrug-resistant clinical isolates of Mycobacterium tuberculosis in France.
    Antimicrob Agents Chemother. 2016 Nov 28. pii: AAC.01299.
    PubMed     Text format     Abstract available


  26. SEBASTIAN J, Swaminath S, Nair RR, Jakkala K, et al
    De Novo Emergence of Genetically Resistant Mutants of Mycobacterium tuberculosis from the Persistence Phase Cells formed against Antituberculosis Drugs In Vitro.
    Antimicrob Agents Chemother. 2016 Nov 28. pii: AAC.01343.
    PubMed     Text format     Abstract available


  27. YEE M, Gopal P, Dick T
    Missense mutations in the unfoldase ClpC1 of the caseinolytic protease complex are associated with pyrazinamide resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2016 Nov 21. pii: AAC.02342.
    PubMed     Text format     Abstract available


  28. ROSEN BC, Dillon NA, Peterson ND, Minato Y, et al
    Long-Chain Fatty Acyl-CoA Ligase FadD2 Mediates Intrinsic Pyrazinamide Resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2016 Nov 14. pii: AAC.02130.
    PubMed     Text format     Abstract available


  29. ANTWI S, Yang H, Enimil A, Sarfo AM, et al
    Pharmacokinetics of the First-line Antituberculosis Drugs in Ghanaian Children with Tuberculosis with and without HIV Coinfection.
    Antimicrob Agents Chemother. 2016 Nov 14. pii: AAC.01701.
    PubMed     Text format     Abstract available


  30. ALFFENAAR JC, Akkerman OW, van Hest R
    Statin Adjunctive Therapy for Tuberculosis Treatment.
    Antimicrob Agents Chemother. 2016;60:7004.
    PubMed     Text format    


    October 2016
  31. PHOLWAT S, Stroup S, Heysell S, Ogarkov O, et al
    Eis C-14G and C-15G mutations do not confer kanamycin resistance in M. tuberculosis.
    Antimicrob Agents Chemother. 2016 Oct 10. pii: AAC.01775.
    PubMed     Text format     Abstract available


    September 2016
  32. WANG X, Yang S, Gu J, Deng J, et al
    Mycobacterium tuberculosis arylamine N-acetyltransferase acetylates and thus inactivates para-aminosalicylic acid.
    Antimicrob Agents Chemother. 2016 Sep 26. pii: AAC.01312.
    PubMed     Text format     Abstract available


  33. LI Y, Wang Y, Zhang Z, Gao H, et al
    Association between embB Codon 306 Mutations, Phenotypic Resistance Profiles and Genotypic Characterization in Clinical Mycobacterium tuberculosis Isolates from Hebei, China.
    Antimicrob Agents Chemother. 2016 Sep 26. pii: AAC.00532.
    PubMed     Text format     Abstract available


    August 2016
  34. NARAN K, Moosa A, Barry CE 3rd, Boshoff HI, et al
    Bioluminescent reporters for rapid mechanism of action assessment in tuberculosis drug discovery.
    Antimicrob Agents Chemother. 2016 Aug 29. pii: AAC.01178.
    PubMed     Text format     Abstract available


  35. ZHANG D, Gomez JE, Chien JY, Haseley N, et al
    Genomic analysis of the evolution of fluoroquinolone resistance in Mycobacterium tuberculosis prior to tuberculosis diagnosis.
    Antimicrob Agents Chemother. 2016 Aug 29. pii: AAC.00664.
    PubMed     Text format     Abstract available


  36. FURIN JJ, Du Bois J, van Brakel E, Chheng P, et al
    Early Bactericidal Activity of AZD5847 in Pulmonary Tuberculosis.
    Antimicrob Agents Chemother. 2016 Aug 22. pii: AAC.01163.
    PubMed     Text format     Abstract available


  37. CHUANG YM, Dutta NK, Hung CF, Wu TC, et al
    The stringent response factors PPX1 and PPK2 play an important role in Mycobacterium tuberculosis metabolism, biofilm formation, and sensitivity to isoniazid in vivo.
    Antimicrob Agents Chemother. 2016 Aug 15. pii: AAC.01139.
    PubMed     Text format     Abstract available


  38. FOO CS, Lechartier B, Kolly GS, Boy-Rottger S, et al
    Characterization of DprE1-mediated benzothiazinone resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2016 Aug 15. pii: AAC.01523.
    PubMed     Text format     Abstract available


  39. NIKONENKO BV, Kornienko A, Majorov K, Ivanov P, et al
    In vitro activity of 3-triazenoindoles against Mycobacterium tuberculosis and Mycobacterium avium.
    Antimicrob Agents Chemother. 2016 Aug 8. pii: AAC.00998.
    PubMed     Text format     Abstract available


  40. PALENCIA A, Li X, Bu W, Choi W, et al
    Discovery of novel oral protein synthesis inhibitors of Mycobacterium tuberculosis that target leucyl-tRNA synthetase.
    Antimicrob Agents Chemother. 2016 Aug 8. pii: AAC.01339.
    PubMed     Text format     Abstract available


  41. CORDES H, Thiel C, Aschmann HE, Baier V, et al
    A PBPK model of isoniazid and its application in individualizing tuberculosis chemotherapy.
    Antimicrob Agents Chemother. 2016 Aug 1. pii: AAC.00508.
    PubMed     Text format     Abstract available


  42. ROCKWOOD NN, Meintjes G, Chirehwa M, Wiesner L, et al
    HIV-1 co-infection does not reduce exposure to rifampicin, isoniazid, and pyrazinamide in South African tuberculosis outpatients.
    Antimicrob Agents Chemother. 2016 Aug 1. pii: AAC.00480.
    PubMed     Text format     Abstract available


  43. PROSSER GA, Rodenburg A, Khoury H, de Chiara C, et al
    Glutamate racemase is the primary target of beta-chloro-D-alanine in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2016 Aug 1. pii: AAC.01249.
    PubMed     Text format     Abstract available


    July 2016
  44. MODONGO C, Pasipanodya JG, Magazi BT, Srivastava S, et al
    Artificial intelligence and amikacin exposures predictive of outcome in multidrug-resistant tuberculosis patients.
    Antimicrob Agents Chemother. 2016 Jul 25. pii: AAC.00962.
    PubMed     Text format     Abstract available


  45. GARCIA-GARCIA V, Oldfield E, Benaim G
    Inhibition of Leishmania mexicana Growth by the Tuberculosis Drug SQ109.
    Antimicrob Agents Chemother. 2016 Jul 25. pii: AAC.00945.
    PubMed     Text format     Abstract available


  46. SRIVASTAVA S, Modongo C, Siyambalapitiyage Dona CW, Pasipanodya JG, et al
    Amikacin optimal exposures targets in the hollow fiber system model of tuberculosis.
    Antimicrob Agents Chemother. 2016 Jul 25. pii: AAC.00961.
    PubMed     Text format     Abstract available


  47. SHAH S, Dalecki AG, Malalasekera AP, Crawford CL, et al
    8-Hydroxyquinolines are boosting-agents of copper related toxicity in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2016 Jul 18. pii: AAC.00325.
    PubMed     Text format     Abstract available


    June 2016
  48. YU X, Wang G, Chen S, Wei G, et al
    Mycobacterium tuberculosis wild-type and non-wild-type MIC distributions for the novel fluoroquinolone antofloxacin compared with ofloxacin, levofloxacin, and moxifloxacin.
    Antimicrob Agents Chemother. 2016 Jun 20. pii: AAC.00393.
    PubMed     Text format     Abstract available


  49. DISRATTHAKIT A, Prammananan T, Tribuddharat C, Thaipisuttikul I, et al
    Gyrase Mutations in Pre-extensively and Extensively Drug-resistant Tuberculosis in Thai Clinical Isolates: Insights into the Role of gyrB Mutations in Quinolone Resistance.
    Antimicrob Agents Chemother. 2016 Jun 13. pii: AAC.00539.
    PubMed     Text format     Abstract available


  50. LI W, Obregon-Henao A, Wallach JB, North EJ, et al
    Therapeutic potential of the Mycobacterium tuberculosis mycolic acid transporter, MmpL3.
    Antimicrob Agents Chemother. 2016 Jun 13. pii: AAC.00826.
    PubMed     Text format     Abstract available


  51. LI D, Hu Y, Werngren J, Mansjo M, et al
    Emergence and genetic characteristics of pyrazinamide resistant tuberculosis in China, a multi-center study.
    Antimicrob Agents Chemother. 2016 Jun 13. pii: AAC.02687.
    PubMed     Text format     Abstract available


  52. DEN HERTOG AL, Menting S, Pfeltz R, Warns M, et al
    PZA is active against Mycobacterium tuberculosis cultures at neutral pH with reduced temperature.
    Antimicrob Agents Chemother. 2016 Jun 6. pii: AAC.00654.
    PubMed     Text format     Abstract available


    May 2016
  53. ZHENG X, Zheng R, Hu Y, Werngren J, et al
    Determination of Minimum Inhibitory Concentration (MIC) Breakpoints for second-line drugs associated with clinical outcomes in multidrug-resistant tuberculosis treatment in China.
    Antimicrob Agents Chemother. 2016 May 31. pii: AAC.03008.
    PubMed     Text format     Abstract available


  54. HU Y, Pertinez H, Ortega-Muro F, Alameda-Martin L, et al
    Investigation of elimination rate, persistent subpopulation removal and relapse rates of Mycobacterium tuberculosis by combinations of first-line drugs in a modified Cornell mouse model.
    Antimicrob Agents Chemother. 2016 May 23. pii: AAC.02548.
    PubMed     Text format     Abstract available


  55. CHIEN JY, Chien ST, Chiu WY, Yu CJ, et al
    Moxifloxacin Improves Treatment Outcomes in Patients with Ofloxacin-resistant Multidrug-resistant Tuberculosis.
    Antimicrob Agents Chemother. 2016 May 23. pii: AAC.00425.
    PubMed     Text format     Abstract available


  56. ALMEIDA D, Ioerger T, Tyagi S, Li SY, et al
    Mutations in pepQ Confer Low-level Resistance to Bedaquiline and Clofazimine in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2016 May 16. pii: AAC.00753.
    PubMed     Text format     Abstract available


  57. LINGARAJU S, Rigouts L, Gupta A, Lee J, et al
    Geographic differences in the contribution of ubiA mutations to high-level Ethambutol Resistance in Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2016 May 2. pii: AAC.03002.
    PubMed     Text format     Abstract available


  58. LANOIX JP, Tasneen R, O'Brien P, Sarathy J, et al
    High systemic exposure of pyrazinoic acid has limited anti-tuberculosis activity in murine and rabbit models of tuberculosis.
    Antimicrob Agents Chemother. 2016 May 2. pii: AAC.03085.
    PubMed     Text format     Abstract available


    April 2016
  59. LEE JY, Lee HJ, Kim YK, Yu S, et al
    Impact of Fluoroquinolone Exposure Prior to Tuberculosis Diagnosis on Clinical Outcomes in Immunocompromised Patients.
    Antimicrob Agents Chemother. 2016 Apr 18. pii: AAC.01749.
    PubMed     Text format     Abstract available


  60. GEORGHIOU SB, Seifert M, Catanzaro D, Garfein RS, et al
    Frequency and Distribution of Tuberculosis Resistance-Associated Mutations between Mumbai, Moldova, and Eastern Cape.
    Antimicrob Agents Chemother. 2016 Apr 18. pii: AAC.00222.
    PubMed     Text format     Abstract available


  61. ALSAAD N, Dijkstra JA, Akkerman OW, de Lange WC, et al
    A pharmacokinetic evaluation of sulfamethoxazole 800 mg once daily in the treatment of tuberculosis.
    Antimicrob Agents Chemother. 2016 Apr 11. pii: AAC.02175.
    PubMed     Text format     Abstract available


  62. EARLY JV, Casey A, Martinez-Grau MA, Valcarcel IC, et al
    Oxadiazoles have butyrate-specific conditional activity against Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2016 Apr 4. pii: AAC.02896.
    PubMed     Text format     Abstract available


    March 2016
  63. MORADIGARAVAND D, Grandjean L, Martinez E, Li H, et al
    DfrA-thyA double deletion in para-aminosalicylic acid resistant Mycobacterium tuberculosis Beijing strains.
    Antimicrob Agents Chemother. 2016 Mar 28. pii: AAC.00253.
    PubMed     Text format     Abstract available


  64. PARVEZ MM, Jung JA, Shin HJ, Kim DH, et al
    Characterization of 22 anti-tuberculosis drugs for the inhibitory interaction potential on organic anionic transporter polypeptides (OATPs) mediated uptake.
    Antimicrob Agents Chemother. 2016 Mar 14. pii: AAC.02765.
    PubMed     Text format     Abstract available


  65. STINSON K, Kurepina N, Venter A, Fujiwara M, et al
    Minimum Inhibitory Concentration of Delamanid (OPC-67683) against Mycobacterium tuberculosis Clinical Isolates and a Proposed Critical Concentration.
    Antimicrob Agents Chemother. 2016 Mar 14. pii: AAC.03014.
    PubMed     Text format     Abstract available


  66. MAKAFE GG, Cao Y, Tan Y, Julius M, et al
    Oxazolidinone Resistance in Mycobacterium tuberculosis: What is the Role of Cys154Arg Mutation in the Ribosomal Protein L3?
    Antimicrob Agents Chemother. 2016 Mar 7. pii: AAC.00152.
    PubMed     Text format     Abstract available


    February 2016
  67. SRIVASTAVA S, van Rijn SP, Wessels AM, Alffenaar JC, et al
    Susceptibility testing of antibiotics that degrade faster than the doubling-time of slow growing Mycobacteria; Ertapenem sterilizing effect versus Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2016 Feb 29. pii: AAC.02924.
    PubMed     Text format     Abstract available


  68. SWANSON R, Ammerman N, Ngcobo B, Adamson J, et al
    Clofazimine contributes sustained antimicrobial activity after treatment cessation in the mouse model of tuberculosis chemotherapy.
    Antimicrob Agents Chemother. 2016 Feb 29. pii: AAC.00177.
    PubMed     Text format     Abstract available


  69. HENDON-DUNN CL, Doris KS, Thomas SR, Allnutt JC, et al
    A flow cytometry method for rapidly assessing M. tuberculosis responses to antibiotics with different modes of action.
    Antimicrob Agents Chemother. 2016 Feb 22. pii: AAC.02712.
    PubMed     Text format     Abstract available


  70. LI QJ, Jiao WW, Yin QQ, Xu F, et al
    Compensatory Mutations of Rifampicin Resistance Are Associated with Transmission of Multidrug Resistant Mycobacterium tuberculosis Beijing genotype strains in China.
    Antimicrob Agents Chemother. 2016 Feb 22. pii: AAC.02358.
    PubMed     Text format     Abstract available


  71. PEARSON CS, Kloos Z, Murray B, Tabe E, et al
    Combined Bioinformatic and Rational Design Approach to Develop Antimicrobial Peptides against Mycobacterium tuberculosis.
    Antimicrob Agents Chemother. 2016 Feb 22. pii: AAC.00940.
    PubMed     Text format     Abstract available


  72. SCHERR N, Pluschke G, Panda M
    A comparative study of activities of a diverse set of anti-mycobacterial agents against Mycobacterium tuberculosis and Mycobacterium ulcerans.
    Antimicrob Agents Chemother. 2016 Feb 16. pii: AAC.02658.
    PubMed     Text format     Abstract available


  73. TURAPOV O, O'Connor BD, Sarybaeva AA, Williams C, et al
    Phenotypically adapted Mycobacterium tuberculosis populations from sputum are tolerant to first line drugs.
    Antimicrob Agents Chemother. 2016 Feb 16. pii: AAC.01380.
    PubMed     Text format     Abstract available


  74. DAS MK, Arya R, Debnath S, Debnath R, et al
    Global urine metabolomics of first line tuberculosis drug treated patients and identification of a novel metabolite of ethambutol.
    Antimicrob Agents Chemother. 2016 Feb 1. pii: AAC.02586.
    PubMed     Text format     Abstract available


    January 2016
  75. ZHANG S, Chen J, Cui P, Shi W, et al
    Mycobacterium tuberculosis Mutations Associated with Reduced Susceptibility to Linezolid.
    Antimicrob Agents Chemother. 2016 Jan 25. pii: AAC.02941.
    PubMed     Text format     Abstract available


  76. BEKKER A, Schaaf HS, Draper HR, van der Laan L, et al
    The pharmacokinetics of rifampicin, isoniazid, pyrazinamide and ethambutol in infants dosed at revised WHO-recommended treatment guidelines.
    Antimicrob Agents Chemother. 2016 Jan 25. pii: AAC.02600.
    PubMed     Text format     Abstract available


  77. CHIEN JY, Chiu WY, Chien ST, Chiang CJ, et al
    Mutations in gyrA and gyrB among Fluoroquinolone- and Multidrug-resistant Mycobacterium tuberculosis Isolates.
    Antimicrob Agents Chemother. 2016 Jan 19. pii: AAC.01049.
    PubMed     Text format     Abstract available


  78. NUERMBERGER E, Sizemore C, Romero K, Hanna D, et al
    Towards an evidence-based non-clinical roadmap for evaluating the efficacy of new TB drug regimens: Proceedings of a Critical Path to TB Drug Regimens (CPTR)-National Institute of Allergy and Infectious Disease (NIAID) in vivo Pharmacology Workshop fo
    Antimicrob Agents Chemother. 2016 Jan 11. pii: AAC.02041.
    PubMed     Text format     Abstract available


    December 2015
  79. LANOIX JP, Betoudji F, Nuermberger E
    Sterilizing activity of pyrazinamide in combination with first-line drugs in a C3HeB/FeJ mouse model of tuberculosis.
    Antimicrob Agents Chemother. 2015 Dec 7. pii: AAC.02637.
    PubMed     Text format     Abstract available


  80. DENTI P, Martinson N, Cohn S, Mashabela F, et al
    Population pharmacokinetics of rifampicin in pregnant women with tuberculosis and HIV co-infection in Soweto, South Africa.
    Antimicrob Agents Chemother. 2015 Dec 7. pii: AAC.02051.
    PubMed     Text format     Abstract available


    November 2015
  81. LANOIX JP, Ioerger T, Ormond A, Kaya F, et al
    Selective inactivity of pyrazinamide against tuberculosis in C3HeB/FeJ mice is best explained by neutral pH of caseum.
    Antimicrob Agents Chemother. 2015 Nov 16. pii: AAC.01370.
    PubMed     Text format     Abstract available


  82. CHIREHWA MT, Rustomjee R, Mthiyane T, Onyebujoh P, et al
    Model-based evaluation of higher doses of rifampicin using a semi-mechanistic model incorporating auto-induction and saturation of hepatic extraction.
    Antimicrob Agents Chemother. 2015 Nov 9. pii: AAC.01830.
    PubMed     Text format     Abstract available


  83. LEE H, Jeong BH, Park HY, Jeon K, et al
    Treatment Outcomes of Fluoroquinolone-Containing Regimens for Isoniazid-Resistant Pulmonary Tuberculosis.
    Antimicrob Agents Chemother. 2015 Nov 2. pii: AAC.01377.
    PubMed     Text format     Abstract available


  84. ZHANG D, Wang Y, Lu J, Pang Y, et al
    In vitro activity of beta-lactams in combination with beta-lactamase inhibitors against multidrug-resistant Mycobacterium tuberculosis isolates.
    Antimicrob Agents Chemother. 2015 Nov 2. pii: AAC.01035.
    PubMed     Text format     Abstract available


    October 2015
  85. SORRENTINO F, Gonzalez Del Rio R, Zheng X, Presa JM, et al
    Development of an intracellular screen for new compounds able to inhibit Mycobacterium tuberculosis growth in human macrophages.
    Antimicrob Agents Chemother. 2015 Oct 26. pii: AAC.01920.
    PubMed     Text format     Abstract available


  86. TASNEEN R, Betoudji F, Tyagi S, Li SY, et al
    Contribution of oxazolidinones to the efficacy of novel regimens containing bedaquiline and pretomanid in a mouse model of tuberculosis.
    Antimicrob Agents Chemother. 2015 Oct 26. pii: AAC.01691.
    PubMed     Text format     Abstract available


  87. HENNIG S, Naiker S, Reddy T, Egan D, et al
    The effect of SLCO1B1 polymorphisms on the pharmacokinetics of rifabutin in African HIV-infected patients with tuberculosis.
    Antimicrob Agents Chemother. 2015 Oct 19. pii: AAC.01195.
    PubMed     Text format     Abstract available


  88. PARK JS, Lee JY, Lee YJ, Kim SJ, et al
    Serum levels of anti-tuberculosis drugs and their effect on tuberculosis treatment outcome.
    Antimicrob Agents Chemother. 2015 Oct 12. pii: AAC.00693.
    PubMed     Text format     Abstract available


  89. MEDELLIN-GARIBAY SE, Cortez-Espinosa N, Milan-Segovia RC, Magana-Aquino M, et al
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