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Amedeo Prize 2008
The 21 Finalists


  Diseases of the Thyroid

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Articles published in J Clin Endocrinol Metab

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    April 2008
  1. SALERNO M , Oliviero U, Lettiero T, Guardasole V, et al
    LONG-TERM CARDIOVASCULAR EFFECTS OF LEVOTHYROXINE THERAPY IN YOUNG ADULTS WITH CONGENITAL HYPOTHYROIDISM.
    J Clin Endocrinol Metab. 2008;.
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  2. LEONARDI D , Polizzotti N, Carta A, Gelsomino R, et al
    LONGITUDINAL STUDY OF THYROID FUNCTION IN CHILDREN WITH MILD HYPERTHYROTROPINEMIA AT NEONATAL SCREENING FOR CONGENITAL HYPOTHYROIDISM.
    J Clin Endocrinol Metab. 2008;.
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  3. AGATE L , Mariotti S, Elisei R, Mossa P, et al
    THYROID AUTOANTIBODIES (ATA) AND THYROID FUNCTION IN SUBJECTS EXPOSED TO CHERNOBYL FALLOUT DURING CHILDHOOD: EVIDENCE FOR A TRANSIENT RADIATION-INDUCED ELEVATION OF SERUM THYROID ANTIBODIES WITHOUT AN INCREASE IN THYROID AUTOIMMUNE DISEASE.
    J Clin Endocrinol Metab. 2008;.
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  4. MOLETI M , Lo Presti VP, Campolo MC, Mattina F, et al
    IODINE PROPHYLAXIS USING IODIZED SALT AND RISK OF MATERNAL THYROID FAILURE IN CONDITIONS OF MILD IODINE DEFICIENCY.
    J Clin Endocrinol Metab. 2008;.
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  5. MIYAUCHI A , Takamura Y, Ito Y, Miya A, et al
    T3 Thyrotoxicosis Due to Increased Conversion of Administered Levothyroxine in Patients with Massive Metastatic Follicular Thyroid Carcinoma.
    J Clin Endocrinol Metab. 2008;.
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  6. EUSTATIA-RUTTEN CF , Corssmit EP, Heemstra KA, Smit JW, et al
    Autonomic nervous system function in chronic exogenous subclinical thyrotoxicosis and the effect of restoring euthyroidism.
    J Clin Endocrinol Metab. 2008;.
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  7. GJEDDE S , Vestergaard ET, Gormsen LC, Riis AL, et al
    Serum ghrelin levels are increased in hypothyroid patients and become normalized by L-thyroxin treatment.
    J Clin Endocrinol Metab. 2008;.
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  8. ENDO T , Ohta K, Kobayashi T
    Expression and function of Cbfa-1/Runx2 in thyroid papillary carcinoma cells.
    J Clin Endocrinol Metab. 2008;.
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  9. MIHAILESCU DV , Schneider AB
    Size, number and distribution of thyroid nodules and their risk of malignancy in radiation-exposed patients who underwent surgery.
    J Clin Endocrinol Metab. 2008;.
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  10. LEBOEUF R , Baumgartner JE, Benezra M, Malaguarnera R, et al
    BRAFV600E mutation is associated with preferential sensitivity to MEK inhibition in thyroid cancer cell lines.
    J Clin Endocrinol Metab. 2008;.
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  11. KLEIN I , Danzi S
    Thyroid hormone treatment to mend a broken heart.
    J Clin Endocrinol Metab. 2008;93:1172-4.
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  12. BRABANT G
    Thyrotropin suppressive therapy in thyroid carcinoma: what are the targets?
    J Clin Endocrinol Metab. 2008;93:1167-9.
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    March 2008
  13. RUSSELL W , Harrison RF, Smith N, Darzy K, et al
    Free triiodothyronine has a distinct circadian rhythm that is delayed but parallels thyrotropin levels.
    J Clin Endocrinol Metab. 2008;.
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  14. MACHENS A , Hauptmann S, Dralle H
    Medullary Thyroid Cancer Responsiveness to Pentagastrin Stimulation: An Early Surrogate Parameter of Tumor Dissemination?
    J Clin Endocrinol Metab. 2008;.
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  15. CHEUNG K , Roman SA, Wang TS, Walker HD, et al
    Calcitonin Measurement in the Evaluation of Thyroid Nodules in the United States: A Cost-effectiveness and Decision Analysis.
    J Clin Endocrinol Metab. 2008;.
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  16. DIMITRIADIS G , Mitrou P, Lambadiari V, Boutati E, et al
    Insulin-stimulated rates of glucose uptake in muscle in hyperthyroidism: the importance of blood flow.
    J Clin Endocrinol Metab. 2008;.
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  17. WUSTMANN K , Kucera JP, Zanchi A, Burow A, et al
    Activation of electrical triggers of atrial fibrillation in hyperthyroidism.
    J Clin Endocrinol Metab. 2008;.
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  18. NAPOLI R , Biondi B, Guardasole V, D'Anna C, et al
    Enhancement of Vascular Endothelial Function by Recombinant Human Thyrotropin.
    J Clin Endocrinol Metab. 2008;.
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  19. WEMEAU JL , Pigeyre M, Proust-Lemoine E, d'Herbomez M, et al
    Beneficial effects of propylthiouracil plus L-thyroxine treatment in a patient with a mutation in MCT8.
    J Clin Endocrinol Metab. 2008;.
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  20. IMAIZUMI M , Ashizawa K, Neriishi K, Akahoshi M, et al
    Thyroid diseases in atomic bomb survivors exposed in utero.
    J Clin Endocrinol Metab. 2008;.
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  21. DAVIES TF
    Infection and autoimmune thyroid disease.
    J Clin Endocrinol Metab. 2008;93:674-6.
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    February 2008
  22. KARMISHOLT J , Andersen S, Laurberg P
    Interval between tests and T4 estimation method influence outcome of monitoring of subclinical hypothyroidism.
    J Clin Endocrinol Metab. 2008;.
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  23. SAMUELS MH , Schuff KG, Carlson NE, Carello P, et al
    Health status, mood and cognition in experimentally-induced subclinical thyrotoxicosis.
    J Clin Endocrinol Metab. 2008;.
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  24. NIKIFOROVA MN , Tseng GC, Steward D, Diorio D, et al
    MicroRNA Expression Profiling of Thyroid Tumors: Biological Significance and Diagnostic Utility.
    J Clin Endocrinol Metab. 2008;.
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  25. KRASSAS GE , Tziomalos K, Papadopoulou F, Pontikides N, et al
    Erectile Dysfunction in Patients with Hyper- and Hypothyroidism: how Common and Should We Treat?
    J Clin Endocrinol Metab. 2008;.
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  26. DIVALL SA , Wondisford FE
    TRH testing in its infancy.
    J Clin Endocrinol Metab. 2008;93:378-9.
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    January 2008
  27. HAMILTON TE , Davis S, Onstad L, Kopecky KJ, et al
    TSH Levels in a Population with No Clinical, Autoantibody, or Ultrasonographic Evidence of Thyroid Disease: Implications for the Diagnosis of Subclinical Hypothyroidism.
    J Clin Endocrinol Metab. 2008;.
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  28. DURAND S , Ferraro-Peyret C, Selmi-Ruby S, Paulin C, et al
    Evaluation of gene expression profiles in thyroid nodule biopsy material to diagnose thyroid cancer.
    J Clin Endocrinol Metab. 2008;.
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  29. KRAUSE K , Eszlinger M, Gimm O, Karger S, et al
    TFF3 based candidate gene discrimination of benign and malignant thyroid tumours in a region with borderline iodine deficiency.
    J Clin Endocrinol Metab. 2008;.
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  30. DI SCIOSCIO V , Loffreda V, Feraco P, Luccaroni R, et al
    Diffuse lipomatosis of thyroid gland.
    J Clin Endocrinol Metab. 2008;93:8-9.
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  31. PALOS F , Garcia-Rendueles ME, Araujo-Vilar D, Obregon MJ, et al
    Pendred syndrome in two Galician families: insights into clinical phenotypes through cellular, genetic, and molecular studies.
    J Clin Endocrinol Metab. 2008;93:267-77.
    PubMed     Related articles    Abstract available


    December 2007
  32. HAYMART MR , Repplinger DJ, Leverson GE, Elson DF, et al
    Higher Serum TSH Level in Thyroid Nodule Patients is Associated with Greater Risks of Differentiated Thyroid Cancer and Advanced Tumor Stage.
    J Clin Endocrinol Metab. 2007;.
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  33. ASAKURA Y , Toyota Y, Muroya K, Kurosawa K, et al
    Endocrine and radiological studies in patients with molecularly confirmed CHARGE syndrome.
    J Clin Endocrinol Metab. 2007;.
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  34. TORLONTANO M , Durante C, Torrente I, Crocetti U, et al
    TYPE 2 DEIODINASE POLYMORPHISM (THR92ALA) PREDICTS L-THYROXINE DOSE TO ACHIEVE TARGET TSH LEVELS IN THYROIDECTOMIZED PATIENTS.
    J Clin Endocrinol Metab. 2007;.
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  35. KONDRASHOVA A , Viskari H, Haapala AM, Seiskari T, et al
    Serological Evidence of Thyroid Autoimmunity Among Schoolchildren in Two Different Socio-Economic Environments.
    J Clin Endocrinol Metab. 2007;.
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  36. ELISEI R , Cosci B, Romei C, Bottici V, et al
    Prognostic significance of somatic RET oncogene mutations in sporadic medullary thyroid cancer: A 10 years follow up study.
    J Clin Endocrinol Metab. 2007;.
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  37. PEARCE EN , Wilson PW, Yang Q, Vasan RS, et al
    Thyroid Function and Lipid Subparticle Sizes in Patients with Short-Term Hypothyroidism and a Population-Based Cohort.
    J Clin Endocrinol Metab. 2007;.
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  38. REBUFFAT SA , Nguyen B, Robert B, Castex F, et al
    Antithyroperoxidase antibodies-dependent cytotoxicity in autoimmune thyroid disease.
    J Clin Endocrinol Metab. 2007;.
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  39. HUBER AK , Jacobson EM, Jazdzewski K, Concepcion ES, et al
    IL-23R IS A MAJOR SUSCEPTIBILITY GENE FOR GRAVES' OPHTHALMOPATHY: THE IL-23/Th17 AXIS EXTENDS TO THYROID AUTOIMMUNITY.
    J Clin Endocrinol Metab. 2007;.
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  40. ROBINSON-WHITE AJ , Hsiao HP, Leitner WW, Greene E, et al
    PKA-Independent Inhibition of Proliferation and Induction of Apoptosis in Human Thyroid Cancer Cells by 8-Cl-Adenosine.
    J Clin Endocrinol Metab. 2007;.
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  41. FATOURECHI V
    Upper limit of normal serum thyroid-stimulating hormone: a moving and now an aging target?
    J Clin Endocrinol Metab. 2007;92:4560-2.
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    November 2007
  42. CHECCHI S , Montanaro A, Pasqui L, Ciuoli C, et al
    L-THYROXINE (L-T4) REQUIREMENT IN PATIENTS WITH AUTOIMMUNE HYPOTHYROIDISM AND PARIETAL CELL ANTIBODIES.
    J Clin Endocrinol Metab. 2007;.
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  43. ZAMPRONI I , Grasberger H, Cortinovis F, Vigone MC, et al
    Biallelic inactivation of the dual oxidase maturation factor 2 (DUOXA2) gene as a novel cause of congenital hypothyroidism.
    J Clin Endocrinol Metab. 2007;.
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  44. BROWN AP , Chen J, Hitchcock YJ, Szabo A, et al
    The Risk of Second Primary Malignancies Up to Three Decades after the Treatment of Differentiated Thyroid Cancer.
    J Clin Endocrinol Metab. 2007;.
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  45. LATROFA F , Ricci D, Grasso L, Vitti P, et al
    Characterization of thyroglobulin epitopes in patients with autoimmune and non-autoimmune thyroid diseases using recombinant human monoclonal thyroglobulin autoantibodies.
    J Clin Endocrinol Metab. 2007;.
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  46. DELADOEY J , Pfarr N, Vuissoz JM, Parma J, et al
    Pseudodominant inheritance of goitrous congenital hypothyroidism caused by TPO mutations: molecular and in silico studies.
    J Clin Endocrinol Metab. 2007;.
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  47. VAN TIJN DA , de Vijlder JJ, Vulsma T
    Role of the Thyrotropin-releasing Hormone Stimulation Test in Diagnosis of Congenital Central Hypothyroidism in Infants.
    J Clin Endocrinol Metab. 2007;.
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  48. ABUBAKER J , Jehan Z, Bavi P, Sultana M, et al
    Clinicopathological analysis of papillary thyroid cancer with PIK3CA alterations in a Middle Eastern population.
    J Clin Endocrinol Metab. 2007;.
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  49. SANTARPIA L , El-Naggar AK, Cote GJ, Myers JN, et al
    PI3K/Akt and Ras/Raf-MAPK pathway mutations in anaplastic thyroid cancer.
    J Clin Endocrinol Metab. 2007;.
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  50. BAHN R , Levy E, Wartofsky L
    Graves' disease.
    J Clin Endocrinol Metab. 2007;92:2 p following 14A.
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    October 2007
  51. CASTAGNA MG , Brilli L, Pilli T, Montanaro A, et al
    Limited Value of Repeat Recombinant Thyrotropin (rhTSH)-Stimulated Thyroglobulin Testing in Differentiated Thyroid Carcinoma Patients With Previous Negative rhTSH-Stimulated Thyroglobulin and Undetectable Basal Serum Thyroglobulin Levels.
    J Clin Endocrinol Metab. 2007;.
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  52. FRAU DV , Lai ML, Caria P, Dettori T, et al
    Trisomy 17 as a Marker For A Subset of Noninvasive Thyroid Nodules With Focal Features of Papillary Carcinoma: Cytogenetic and Molecular Analysis of 62 Cases and Correlation with Histologic Findings.
    J Clin Endocrinol Metab. 2007;.
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  53. HOFTIJZER HC , Heemstra KA, Corssmit EP, van der Klaauw AA, et al
    Quality of Life in Cured Patients with Differentiated Thyroid Carcinoma.
    J Clin Endocrinol Metab. 2007;.
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  54. MORENO-REYES R , Tang BN, Seret A, Goldman S, et al
    Impaired Iodide Organification in Autonomous Thyroid Nodules.
    J Clin Endocrinol Metab. 2007;.
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  55. LIU D , Liu Z, Jiang D, Dackiw AP, et al
    Inhibitory Effects of the MEK Inhibitor CI-1040 on the Proliferation and Tumor Growth of Thyroid Cancer Cells with BRAF or RAS Mutations.
    J Clin Endocrinol Metab. 2007;.
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  56. JOSEPH B , Ji M, Liu D, Hou P, et al
    Lack of Mutations in the Thyroid Hormone Receptor {alpha} and {beta} Genes, but Frequent Hypermethylation of the Thyroid Hormone Receptor {beta} Gene in Differentiated Thyroid Tumors.
    J Clin Endocrinol Metab. 2007;.
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  57. SURKS MI , Hollowell JG
    Age-Specific Distribution of Serum TSH and Antithyroid Antibodies in the United States Population; Implications for the Prevalence of Subclinical Hypothyroidism.
    J Clin Endocrinol Metab. 2007;.
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  58. EL FASSI D , Clemmensen O, Nielsen CH, Silkiss RZ, et al
    Evidence of Intrathyroidal B-Lymphocyte Depletion after rituximab Therapy in a Patient with Graves' Disease.
    J Clin Endocrinol Metab. 2007;92:3762-3.
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  59. RIDGWAY EC , Tomer Y, McLachlan SM
    Update in thyroidology.
    J Clin Endocrinol Metab. 2007;92:3755-61.
    PubMed     Related articles    Abstract available


    September 2007
  60. ELISEI R , Romei C, Cosci B, Agate L, et al
    Ret Genetic Screening in Patients with Medullary Thyroid Cancer and Their Relatives: Experience with 807 Individuals at One Center.
    J Clin Endocrinol Metab. 2007;.
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  61. OUDOUX A , Salaun PY, Bournaud C, Campion L, et al
    Sensitivity and Prognostic Value of Positron Emission Tomography with F-18-Fluorodeoxyglucose and Sensitivity of Immunoscintigraphy in Patients with Medullary Thyroid Carcinoma Treated with Anti-CEA-Targeted Radioimmunotherapy.
    J Clin Endocrinol Metab. 2007;.
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  62. BALL DW , Jin N, Rosen DM, Dackiw A, et al
    Selective Growth Inhibition in BRAF Mutant Thyroid Cancer by the MEK 1/2 Inhibitor AZD6244 (ARRY-142886).
    J Clin Endocrinol Metab. 2007;.
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  63. MITSIADES CS , Hayden P, Kotoula V, McMillin DW, et al
    Bcl-2 Overexpression in Thyroid Carcinoma Cells Increases Sensitivity to Bcl-2 Homology 3 Domain Inhibition.
    J Clin Endocrinol Metab. 2007;.
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  64. MARTINS MR , Doin FC, Komatsu WR, Barros-Neto TL, et al
    Growth Hormone Replacement Improves Thyroxine Biological Effects: Implications for Management of Central Hypothyroidism.
    J Clin Endocrinol Metab. 2007;.
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  65. LUPI C , Giannini R, Ugolini C, Proietti A, et al
    Association of BRAF V600E Mutation with Poor Clinicopathologic Outcomes in 500 Consecutive Cases of Papillary Thyroid Carcinoma.
    J Clin Endocrinol Metab. 2007;.
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  66. CAPPOLA AR
    Subclinical Thyroid Dysfunction and the Heart.
    J Clin Endocrinol Metab. 2007;92:3404-3405.
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    August 2007
  67. GIRAUDET AL , Vanel D, Leboulleux S, Auperin A, et al
    Imaging medullary thyroid carcinoma with persistent elevated calcitonin levels.
    J Clin Endocrinol Metab. 2007;.
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  68. LAUKKARINEN J , Kiudelis G, Lempinen M, Raty S, et al
    Increased Prevalence of Subclinical Hypothyroidism in Common Bile Duct Stone Patients.
    J Clin Endocrinol Metab. 2007;.
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  69. SLAWIK M , Klawitter B, Meiser E, Schories M, et al
    Thyroid Hormone Replacement for Central Hypothyroidism: A Randomized Controlled Trial Comparing Two Doses of Thyroxine With a Combination of Thyroxine and Triiodothyronine.
    J Clin Endocrinol Metab. 2007;.
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  70. DARDANO A , Ballardin M, Ferdeghini M, Lazzeri E, et al
    Anticlastogenic Effect of Ginkgo biloba Extract in Graves' Disease Patients Receiving Radioiodine Therapy.
    J Clin Endocrinol Metab. 2007;.
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  71. LAURITANO EC , Bilotta AL, Gabrielli M, Scarpellini E, et al
    Association Between Hypothyroidism and Small Intestinal Bacterial Overgrowth.
    J Clin Endocrinol Metab. 2007;.
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  72. SPENCER CA , Hollowell JG, Kazarosyan M, Braverman LE, et al
    NHANES III TSH:TPOAb Relationships Demonstrate that TSH Upper Reference Limits May be Skewed by Occult Thyroid Dysfunction.
    J Clin Endocrinol Metab. 2007;.
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  73. SEBASTIANES FM , Cerci JJ, Zanoni PH, Soares J Jr, et al
    Role of 18F-FDG PET in Preoperative Assessment of Cytologically Indeterminate Thyroid Nodules.
    J Clin Endocrinol Metab. 2007;.
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  74. SNOZEK CL , Chambers EP, Reading CC, Sebo TJ, et al
    Serum thyroglobulin, high resolution ultrasound and lymph node thyroglobulin in diagnosis of differentiated thyroid carcinoma nodal metastases.
    J Clin Endocrinol Metab. 2007;.
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  75. GIOVANELLA L , Ceriani L, Crippa S, Mazzucchelli L, et al
    Langherans Cell Histiocytosis of the Thyroid Gland Detected by 18FDG-PET/CT.
    J Clin Endocrinol Metab. 2007;92:2866-7.
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  76. The Hormone Foundation's patient guide to the management of maternal hypothyroidism before, during and after pregnancy.
    J Clin Endocrinol Metab. 2007;92:2 p following 10A.
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  77. HOMONCIK M , Gessl A, Ferlitsch A, Jilma B, et al
    Altered platelet plug formation in hyperthyroidism and hypothyroidism.
    J Clin Endocrinol Metab. 2007;92:3006-12.
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  78. OLIVIERI A , Medda E, De Angelis S, Valensise H, et al
    High risk of congenital hypothyroidism in multiple pregnancies.
    J Clin Endocrinol Metab. 2007;92:3141-7.
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  79. ABALOVICH M , Amino N, Barbour LA, Cobin RH, et al
    Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society Clinical Practice Guideline.
    J Clin Endocrinol Metab. 2007;92.
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    July 2007
  80. SONG Y , Driessens N, Costa M, De Deken X, et al
    Roles of hydrogen peroxide in thyroid physiology and disease.
    J Clin Endocrinol Metab. 2007;.
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  81. VOLZKE H , Friedrich N, Schipf S, Haring R, et al
    ASSOCIATION BETWEEN SERUM IGF-1 LEVELS AND THYROID DISORDERS IN A POPULATION-BASED STUDY.
    J Clin Endocrinol Metab. 2007;.
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  82. PILLI T , Brianzoni E, Capoccetti F, Castagna MG, et al
    A comparison of 1850 MBq (50 mCi) and 3700 MBq (100 mCi) 131-iodine administered doses for recombinant TSH-stimulated postoperative thyroid remnant ablation in differentiated thyroid cancer.
    J Clin Endocrinol Metab. 2007;.
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  83. MARKOVIC V , Eterovic D
    Thyroid echogenicity predicts outcome of radioiodine therapy in patients with Graves' disease.
    J Clin Endocrinol Metab. 2007;.
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  84. LAN L , Cui D, Nowka K, Derwahl M, et al
    Stem cells derived from goiters in adults form spheres in response to intense growth stimulation and require TSH for differentiation into thyrocytes.
    J Clin Endocrinol Metab. 2007;.
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  85. LEBOULLEUX S , Girard E, Rose M, Travagli JP, et al
    Ultrasound criteria of malignancy for cervical lymph nodes in patients followed for differentiated thyroid cancer.
    J Clin Endocrinol Metab. 2007;.
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  86. DURANTE C , Puxeddu E, Ferretti E, Morisi R, et al
    BRAF mutations in papillary thyroid carcinomas inhibit genes involved in iodine metabolism.
    J Clin Endocrinol Metab. 2007;92:2840-3.
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  87. SAMUELS MH , Schuff KG, Carlson NE, Carello P, et al
    Health status, mood, and cognition in experimentally induced subclinical hypothyroidism.
    J Clin Endocrinol Metab. 2007;92:2545-51.
    PubMed     Related articles    Abstract available


  88. VOLZKE H , Schwahn C, Wallaschofski H, Dorr M, et al
    Review: The association of thyroid dysfunction with all-cause and circulatory mortality: is there a causal relationship?
    J Clin Endocrinol Metab. 2007;92:2421-9.
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  89. GRASBERGER H , Van Sande J, Hag-Dahood Mahameed A, Tenenbaum-Rakover Y, et al
    A familial thyrotropin (TSH) receptor mutation provides in vivo evidence that the inositol phosphates/Ca2+ cascade mediates TSH action on thyroid hormone synthesis.
    J Clin Endocrinol Metab. 2007;92:2816-20.
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  90. SMIT JW , Stokkel MP, Pereira AM, Romijn JA, et al
    Bexarotene-induced hypothyroidism: bexarotene stimulates the peripheral metabolism of thyroid hormones.
    J Clin Endocrinol Metab. 2007;92:2496-9.
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  91. SQUIZZATO A , Romualdi E, Buller HR, Gerdes VE, et al
    Clinical review: Thyroid dysfunction and effects on coagulation and fibrinolysis: a systematic review.
    J Clin Endocrinol Metab. 2007;92:2415-20.
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  92. SCHLUMBERGER M , Hitzel A, Toubert ME, Corone C, et al
    Comparison of seven serum thyroglobulin assays in the follow-up of papillary and follicular thyroid cancer patients.
    J Clin Endocrinol Metab. 2007;92:2487-95.
    PubMed     Related articles    Abstract available


  93. HOVENS GC , Stokkel MP, Kievit J, Corssmit EP, et al
    Associations of serum thyrotropin concentrations with recurrence and death in differentiated thyroid cancer.
    J Clin Endocrinol Metab. 2007;92:2610-5.
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  94. WANG PW , Chen IY, Liu RT, Hsieh CJ, et al
    Cytotoxic T lymphocyte-associated molecule-4 gene polymorphism and hyperthyroid Graves' disease relapse after antithyroid drug withdrawal: a follow-up study.
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