Vaccine effectiveness for laboratory-confirmed influenza in children 6-59 months of age, 2005-2007

Vaccine. 2011 Nov 8;29(48):9005-11. doi: 10.1016/j.vaccine.2011.09.037. Epub 2011 Sep 21.

Abstract

To estimate the effectiveness of influenza vaccine against medical care visits for laboratory-confirmed influenza in young children we conducted a matched case-control study in children with acute respiratory illness or fever from 2005-2007. Influenza vaccine effectiveness (VE) was calculated using cases with laboratory-confirmed influenza and controls who tested negative for influenza. The effectiveness of influenza vaccine in fully vaccinated children 6-59 months of age was 56% (95% CI: 25%-74%); a significant VE was not found for partial vaccination.

Publication types

  • Multicenter Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Case-Control Studies
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Influenza Vaccines / administration & dosage*
  • Influenza Vaccines / immunology
  • Influenza, Human / diagnosis
  • Influenza, Human / prevention & control*
  • Male
  • Population Surveillance*
  • Prospective Studies
  • Vaccines, Inactivated / administration & dosage
  • Vaccines, Inactivated / immunology

Substances

  • Influenza Vaccines
  • Vaccines, Inactivated