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  Alzheimer's Disease

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Articles published in Acta Neuropathol

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Single Articles


    February 2024
  1. ALEXANDER A, Alvarez VE, Huber BR, Alosco ML, et al
    Cortical-sparing chronic traumatic encephalopathy (CSCTE): a distinct subtype of CTE.
    Acta Neuropathol. 2024;147:45.
    PubMed     Abstract available


  2. MALIK N, Miah MU, Galgani A, McAleese K, et al
    Regional AT-8 reactive tau species correlate with intracellular Abeta levels in cases of low AD neuropathologic change.
    Acta Neuropathol. 2024;147:40.
    PubMed     Abstract available


  3. WU YC, Bogale TA, Koistinaho J, Pizzi M, et al
    The contribution of beta-amyloid, Tau and alpha-synuclein to blood-brain barrier damage in neurodegenerative disorders.
    Acta Neuropathol. 2024;147:39.
    PubMed     Abstract available


  4. COLOM-CADENA M, Toombs J, Simzer E, Holt K, et al
    Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease.
    Acta Neuropathol. 2024;147:32.
    PubMed     Abstract available


  5. OERTEL FC, Casillas D, Cobigo Y, Condor Montes S, et al
    Scientific commentary on: "Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer's disease and primary tauopathies".
    Acta Neuropathol. 2024;147:30.
    PubMed    


  6. CHUNG M, Carter EK, Veire AM, Dammer EB, et al
    Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains.
    Acta Neuropathol. 2024;147:29.
    PubMed     Abstract available


    January 2024
  7. LEITNER D, Pires G, Kavanagh T, Kanshin E, et al
    Similar brain proteomic signatures in Alzheimer's disease and epilepsy.
    Acta Neuropathol. 2024;147:27.
    PubMed     Abstract available


  8. AGUERO C, Dhaynaut M, Amaral AC, Moon SH, et al
    Head-to-head comparison of [(18)F]-Flortaucipir, [(18)F]-MK-6240 and [(18)F]-PI-2620 postmortem binding across the spectrum of neurodegenerative diseases.
    Acta Neuropathol. 2024;147:25.
    PubMed     Abstract available


  9. FAZELI E, Child DD, Bucks SA, Stovarsky M, et al
    A familial missense variant in the Alzheimer's disease gene SORL1 impairs its maturation and endosomal sorting.
    Acta Neuropathol. 2024;147:20.
    PubMed     Abstract available


  10. VAN DER GAAG BL, Deshayes NAC, Breve JJP, Bol JGJM, et al
    Distinct tau and alpha-synuclein molecular signatures in Alzheimer's disease with and without Lewy bodies and Parkinson's disease with dementia.
    Acta Neuropathol. 2024;147:14.
    PubMed     Abstract available


  11. LANTERO-RODRIGUEZ J, Montoliu-Gaya L, Benedet AL, Vrillon A, et al
    CSF p-tau205: a biomarker of tau pathology in Alzheimer's disease.
    Acta Neuropathol. 2024;147:12.
    PubMed     Abstract available


  12. AGRA ALMEIDA QUADROS AR, Li Z, Wang X, Ndayambaje IS, et al
    Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer's disease.
    Acta Neuropathol. 2024;147:9.
    PubMed     Abstract available


  13. TAYLOR LW, Simzer EM, Pimblett C, Lacey-Solymar OTT, et al
    p-tau Ser356 is associated with Alzheimer's disease pathology and is lowered in brain slice cultures using the NUAK inhibitor WZ4003.
    Acta Neuropathol. 2024;147:7.
    PubMed     Abstract available


    December 2023
  14. MONTOLIU-GAYA L, Alosco ML, Yhang E, Tripodis Y, et al
    Optimal blood tau species for the detection of Alzheimer's disease neuropathology: an immunoprecipitation mass spectrometry and autopsy study.
    Acta Neuropathol. 2023;147:5.
    PubMed     Abstract available


  15. CHANG K, Ling JP, Redding-Ochoa J, An Y, et al
    Loss of TDP-43 splicing repression occurs early in the aging population and is associated with Alzheimer's disease neuropathologic changes and cognitive decline.
    Acta Neuropathol. 2023;147:4.
    PubMed     Abstract available


    November 2023
  16. VANDEVREDE L, La Joie R, Horiki S, Mundada NS, et al
    Co-pathology may impact outcomes of amyloid-targeting treatments: clinicopathological results from two patients treated with aducanumab.
    Acta Neuropathol. 2023;146:777-781.
    PubMed    


    September 2023
  17. SORDO L, Qian T, Bukhari SA, Nguyen KM, et al
    Characterization of hippocampal sclerosis of aging and its association with other neuropathologic changes and cognitive deficits in the oldest-old.
    Acta Neuropathol. 2023;146:415-432.
    PubMed     Abstract available


    August 2023
  18. NGUYEN AT, Wang K, Hu G, Wang X, et al
    Correction: APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer's disease.
    Acta Neuropathol. 2023 Aug 17. doi: 10.1007/s00401-023-02620.
    PubMed    


  19. JUDD JM, Jasbi P, Winslow W, Serrano GE, et al
    Inflammation and the pathological progression of Alzheimer's disease are associated with low circulating choline levels.
    Acta Neuropathol. 2023 Aug 7. doi: 10.1007/s00401-023-02616.
    PubMed     Abstract available


  20. MATE DE GERANDO A, Welikovitch LA, Khasnavis A, Commins C, et al
    Tau seeding and spreading in vivo is supported by both AD-derived fibrillar and oligomeric tau.
    Acta Neuropathol. 2023;146:191-210.
    PubMed     Abstract available


    July 2023
  21. NEUMANN M, Perneel J, Cheung S, Van den Broeck M, et al
    Limbic-predominant age-related TDP-43 proteinopathy (LATE-NC) is associated with abundant TMEM106B pathology.
    Acta Neuropathol. 2023;146:163-166.
    PubMed    


  22. YU L, Boyle PA, Janelidze S, Petyuk VA, et al
    Plasma p-tau181 and p-tau217 in discriminating PART, AD and other key neuropathologies in older adults.
    Acta Neuropathol. 2023;146:1-11.
    PubMed     Abstract available


    June 2023
  23. BERMUDEZ C, Graff-Radford J, Syrjanen JA, Stricker NH, et al
    Plasma biomarkers for prediction of Alzheimer's disease neuropathologic change.
    Acta Neuropathol. 2023 Jun 3. doi: 10.1007/s00401-023-02594.
    PubMed     Abstract available


  24. FILIPELLO F, You SF, Mirfakhar FS, Mahali S, et al
    Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation.
    Acta Neuropathol. 2023;145:749-772.
    PubMed     Abstract available


    May 2023
  25. MANCA M, Standke HG, Browne DF, Huntley ML, et al
    Tau seeds occur before earliest Alzheimer's changes and are prevalent across neurodegenerative diseases.
    Acta Neuropathol. 2023 May 8. doi: 10.1007/s00401-023-02574.
    PubMed     Abstract available


  26. HOQ MR, Bharath SR, Hallinan GI, Fernandez A, et al
    Cross-beta helical filaments of Tau and TMEM106B in gray and white matter of multiple system tauopathy with presenile dementia.
    Acta Neuropathol. 2023;145:707-710.
    PubMed    


    March 2023
  27. CHENG Y, He CY, Tian DY, Chen SH, et al
    Physiological beta-amyloid clearance by the liver and its therapeutic potential for Alzheimer's disease.
    Acta Neuropathol. 2023 Mar 25. doi: 10.1007/s00401-023-02559.
    PubMed     Abstract available


  28. WINFREE RL, Seto M, Dumitrescu L, Menon V, et al
    TREM2 gene expression associations with Alzheimer's disease neuropathology are region-specific: implications for cortical versus subcortical microglia.
    Acta Neuropathol. 2023 Mar 25. doi: 10.1007/s00401-023-02564.
    PubMed     Abstract available


  29. YANG Y, Zhang W, Murzin AG, Schweighauser M, et al
    Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains.
    Acta Neuropathol. 2023;145:325-333.
    PubMed     Abstract available


    February 2023
  30. BOZA-SERRANO A, Ruiz R, Sanchez-Varo R, Garcia-Revilla J, et al
    Correction to: Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease.
    Acta Neuropathol. 2023 Feb 15. doi: 10.1007/s00401-023-02549.
    PubMed    


  31. KORONYO Y, Rentsendorj A, Mirzaei N, Regis GC, et al
    Retinal pathological features and proteome signatures of Alzheimer's disease.
    Acta Neuropathol. 2023 Feb 11. doi: 10.1007/s00401-023-02548.
    PubMed     Abstract available


  32. NELSON PT, Lee EB, Cykowski MD, Alafuzoff I, et al
    LATE-NC staging in routine neuropathologic diagnosis: an update.
    Acta Neuropathol. 2023;145:159-173.
    PubMed     Abstract available


    January 2023
  33. KIM YA, Siddiqui T, Blaze J, Cosacak MI, et al
    RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation.
    Acta Neuropathol. 2023;145:29-48.
    PubMed     Abstract available


    December 2022
  34. HART DE RUYTER FJ, Morrema THJ, den Haan J, Twisk JWR, et al
    Correction to: Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer's disease and primary tauopathies.
    Acta Neuropathol. 2022 Dec 23. doi: 10.1007/s00401-022-02534.
    PubMed    


  35. SCADUTO P, Lauterborn JC, Cox CD, Fracassi A, et al
    Functional excitatory to inhibitory synaptic imbalance and loss of cognitive performance in people with Alzheimer's disease neuropathologic change.
    Acta Neuropathol. 2022 Dec 20. doi: 10.1007/s00401-022-02526.
    PubMed     Abstract available


  36. MOONEN S, Koper MJ, Van Schoor E, Schaeverbeke JM, et al
    Pyroptosis in Alzheimer's disease: cell type-specific activation in microglia, astrocytes and neurons.
    Acta Neuropathol. 2022 Dec 9. doi: 10.1007/s00401-022-02528.
    PubMed     Abstract available


  37. HART DE RUYTER FJ, Morrema THJ, den Haan J, Twisk JWR, et al
    Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer's disease and primary tauopathies.
    Acta Neuropathol. 2022 Dec 8. doi: 10.1007/s00401-022-02525.
    PubMed     Abstract available


  38. ICHIMATA S, Martinez-Valbuena I, Forrest SL, Kovacs GG, et al
    Expanding the spectrum of amyloid-beta plaque pathology: the Down syndrome associated 'bird-nest plaque'.
    Acta Neuropathol. 2022;144:1171-1174.
    PubMed    


  39. NGUYEN AT, Kouri N, Labuzan SA, Przybelski SA, et al
    Neuropathologic scales of cerebrovascular disease associated with diffusion changes on MRI.
    Acta Neuropathol. 2022;144:1117-1125.
    PubMed     Abstract available


    October 2022
  40. GILVESY A, Husen E, Magloczky Z, Mihaly O, et al
    Spatiotemporal characterization of cellular tau pathology in the human locus coeruleus-pericoerulear complex by three-dimensional imaging.
    Acta Neuropathol. 2022;144:651-676.
    PubMed     Abstract available


    September 2022
  41. KIM B, Suh E, Nguyen AT, Prokop S, et al
    TREM2 risk variants are associated with atypical Alzheimer's disease.
    Acta Neuropathol. 2022 Sep 16. pii: 10.1007/s00401-022-02495.
    PubMed     Abstract available


  42. SHANG Y, Sun X, Chen X, Wang Q, et al
    A CHCHD6-APP axis connects amyloid and mitochondrial pathology in Alzheimer's disease.
    Acta Neuropathol. 2022 Sep 14. pii: 10.1007/s00401-022-02499.
    PubMed     Abstract available


  43. JANSEN IE, van der Lee SJ, Gomez-Fonseca D, de Rojas I, et al
    Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers.
    Acta Neuropathol. 2022 Sep 6. pii: 10.1007/s00401-022-02454.
    PubMed     Abstract available


  44. BOTELLA LUCENA P, Vanherle S, Lodder C, Gutierrez de Rave M, et al
    Blood-based Abeta42 increases in the earliest pre-pathological stage before decreasing with progressive amyloid pathology in preclinical models and human subjects: opening new avenues for prevention.
    Acta Neuropathol. 2022;144:489-508.
    PubMed     Abstract available


    August 2022
  45. COUGHLIN DG, Goodwill VS, Standke HG, Kim Y, et al
    Selective tau seeding assays and isoform-specific antibodies define neuroanatomic distribution of progressive supranuclear palsy pathology arising in Alzheimer's disease.
    Acta Neuropathol. 2022 Aug 18. pii: 10.1007/s00401-022-02480.
    PubMed    


  46. GAO F, Hu M, Zhang J, Hashem J, et al
    TDP-43 drives synaptic and cognitive deterioration following traumatic brain injury.
    Acta Neuropathol. 2022;144:187-210.
    PubMed     Abstract available


    July 2022
  47. BOZA-SERRANO A, Vrillon A, Minta K, Paulus A, et al
    Galectin-3 is elevated in CSF and is associated with Abeta deposits and tau aggregates in brain tissue in Alzheimer's disease.
    Acta Neuropathol. 2022 Jul 27. pii: 10.1007/s00401-022-02469.
    PubMed     Abstract available


  48. AREZOUMANDAN S, Xie SX, Cousins KAQ, Mechanic-Hamilton DJ, et al
    Regional distribution and maturation of tau pathology among phenotypic variants of Alzheimer's disease.
    Acta Neuropathol. 2022 Jul 23. pii: 10.1007/s00401-022-02472.
    PubMed     Abstract available


  49. SEPULVEDA-FALLA D, Sanchez JS, Almeida MC, Boassa D, et al
    Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer's dementia.
    Acta Neuropathol. 2022 Jul 15. pii: 10.1007/s00401-022-02467.
    PubMed     Abstract available


  50. DENG Y, Bi M, Delerue F, Forrest SL, et al
    Loss of LAMP5 interneurons drives neuronal network dysfunction in Alzheimer's disease.
    Acta Neuropathol. 2022 Jul 3. pii: 10.1007/s00401-022-02457.
    PubMed     Abstract available


  51. WANG SJ, Guo Y, Ervin JF, Lusk JB, et al
    Neuropathological associations of limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) differ between the oldest-old and younger-old.
    Acta Neuropathol. 2022;144:45-57.
    PubMed     Abstract available


    June 2022
  52. LYSSENKO NN, Shi X, Pratico D
    The Alzheimer's disease GWAS risk alleles in the ABCA7 promoter and 5' region reduce ABCA7 expression.
    Acta Neuropathol. 2022 Jun 27. pii: 10.1007/s00401-022-02459.
    PubMed    


  53. NELSON PT, Brayne C, Flanagan ME, Abner EL, et al
    Frequency of LATE neuropathologic change across the spectrum of Alzheimer's disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts.
    Acta Neuropathol. 2022 Jun 13. pii: 10.1007/s00401-022-02444.
    PubMed     Abstract available


  54. LLOYD GM, Sorrentino ZA, Quintin S, Gorion KM, et al
    Unique seeding profiles and prion-like propagation of synucleinopathies are highly dependent on the host in human alpha-synuclein transgenic mice.
    Acta Neuropathol. 2022;143:663-685.
    PubMed     Abstract available


    May 2022
  55. LEE AJ, Raghavan NS, Bhattarai P, Siddiqui T, et al
    FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer's disease.
    Acta Neuropathol. 2022 May 24. pii: 10.1007/s00401-022-02431.
    PubMed     Abstract available


  56. PLOWEY ED, Bussiere T, Rajagovindan R, Sebalusky J, et al
    Alzheimer disease neuropathology in a patient previously treated with aducanumab.
    Acta Neuropathol. 2022 May 17. pii: 10.1007/s00401-022-02433.
    PubMed     Abstract available


  57. CHEN S, Acosta D, Li L, Liang J, et al
    Wolframin is a novel regulator of tau pathology and neurodegeneration.
    Acta Neuropathol. 2022;143:547-569.
    PubMed     Abstract available


  58. CYKOWSKI MD, Arumanayagam AS, Powell SZ, Rivera AL, et al
    Patterns of amygdala region pathology in LATE-NC: subtypes that differ with regard to TDP-43 histopathology, genetic risk factors, and comorbid pathologies.
    Acta Neuropathol. 2022;143:531-545.
    PubMed     Abstract available


    April 2022
  59. JIN Y, Li F, Sonoustoun B, Kondru NC, et al
    APOE4 exacerbates alpha-synuclein seeding activity and contributes to neurotoxicity in Alzheimer's disease with Lewy body pathology.
    Acta Neuropathol. 2022 Apr 26. pii: 10.1007/s00401-022-02421.
    PubMed     Abstract available


  60. BOUTER Y, Liekefeld H, Pichlo S, Westhoff AC, et al
    Donanemab detects a minor fraction of amyloid-beta plaques in post-mortem brain tissue of patients with Alzheimer's disease and Down syndrome.
    Acta Neuropathol. 2022 Apr 16. pii: 10.1007/s00401-022-02418.
    PubMed    


  61. RAMANAN VK, Heckman MG, Lesnick TG, Przybelski SA, et al
    Tau polygenic risk scoring: a cost-effective aid for prognostic counseling in Alzheimer's disease.
    Acta Neuropathol. 2022 Apr 12. pii: 10.1007/s00401-022-02419.
    PubMed     Abstract available


  62. BARON T, Arsac JN, Verchere J, Tlili H, et al
    Co-expression of APP/PS1 disrupts the distribution of brain lesions in a synucleinopathy transgenic mouse model (M83).
    Acta Neuropathol. 2022;143:527-529.
    PubMed    


    March 2022
  63. KAPASI A, Yu L, Petyuk V, Arfanakis K, et al
    Association of small vessel disease with tau pathology.
    Acta Neuropathol. 2022;143:349-362.
    PubMed     Abstract available


  64. PEROSA V, Oltmer J, Munting LP, Freeze WM, et al
    Perivascular space dilation is associated with vascular amyloid-beta accumulation in the overlying cortex.
    Acta Neuropathol. 2022;143:331-348.
    PubMed     Abstract available


    February 2022
  65. SMIRNOV DS, Ashton NJ, Blennow K, Zetterberg H, et al
    Plasma biomarkers for Alzheimer's Disease in relation to neuropathology and cognitive change.
    Acta Neuropathol. 2022 Feb 23. pii: 10.1007/s00401-022-02408.
    PubMed     Abstract available


  66. KAESER SA, Hasler LM, Lambert M, Bergmann C, et al
    CSF p-tau increase in response to Abeta-type and Danish-type cerebral amyloidosis and in the absence of neurofibrillary tangles.
    Acta Neuropathol. 2022;143:287-290.
    PubMed    


  67. BOWLES KR, Pugh DA, Oja LM, Jadow BM, et al
    Dysregulated coordination of MAPT exon 2 and exon 10 splicing underlies different tau pathologies in PSP and AD.
    Acta Neuropathol. 2022;143:225-243.
    PubMed     Abstract available


    January 2022
  68. UEMURA MT, Robinson JL, Cousins KAQ, Tropea TF, et al
    Distinct characteristics of limbic-predominant age-related TDP-43 encephalopathy in Lewy body disease.
    Acta Neuropathol. 2022;143:15-31.
    PubMed     Abstract available


    November 2021
  69. SMITH AM, Davey K, Tsartsalis S, Khozoie C, et al
    Diverse human astrocyte and microglial transcriptional responses to Alzheimer's pathology.
    Acta Neuropathol. 2021 Nov 12. pii: 10.1007/s00401-021-02372.
    PubMed     Abstract available


    October 2021
  70. MCALEESE KE, Miah M, Graham S, Hadfield GM, et al
    Frontal white matter lesions in Alzheimer's disease are associated with both small vessel disease and AD-associated cortical pathology.
    Acta Neuropathol. 2021 Oct 4. pii: 10.1007/s00401-021-02376.
    PubMed     Abstract available


  71. ROOS TT, Garcia MG, Martinsson I, Mabrouk R, et al
    Neuronal spreading and plaque induction of intracellular Abeta and its disruption of Abeta homeostasis.
    Acta Neuropathol. 2021;142:669-687.
    PubMed     Abstract available


  72. MAO F, Robinson JL, Unger T, Posavi M, et al
    TMEM106B modifies TDP-43 pathology in human ALS brain and cell-based models of TDP-43 proteinopathy.
    Acta Neuropathol. 2021;142:629-642.
    PubMed     Abstract available


    September 2021
  73. FELEKE R, Reynolds RH, Smith AM, Tilley B, et al
    Cross-platform transcriptional profiling identifies common and distinct molecular pathologies in Lewy body diseases.
    Acta Neuropathol. 2021;142:449-474.
    PubMed     Abstract available


    August 2021
  74. HALLINAN GI, Hoq MR, Ghosh M, Vago FS, et al
    Structure of Tau filaments in Prion protein amyloidoses.
    Acta Neuropathol. 2021;142:227-241.
    PubMed     Abstract available


  75. WALLON D, Boluda S, Rovelet-Lecrux A, Thierry M, et al
    Clinical and neuropathological diversity of tauopathy in MAPT duplication carriers.
    Acta Neuropathol. 2021;142:259-278.
    PubMed     Abstract available


    July 2021
  76. CHEN CD, Joseph-Mathurin N, Sinha N, Zhou A, et al
    Comparing amyloid-beta plaque burden with antemortem PiB PET in autosomal dominant and late-onset Alzheimer disease.
    Acta Neuropathol. 2021 Jul 28. pii: 10.1007/s00401-021-02342.
    PubMed     Abstract available


    June 2021
  77. DIAZ-LUCENA D, Kruse N, Thune K, Schmitz M, et al
    TREM2 expression in the brain and biological fluids in prion diseases.
    Acta Neuropathol. 2021;141:841-859.
    PubMed     Abstract available


    May 2021
  78. JAUNMUKTANE Z, Banerjee G, Paine S, Parry-Jones A, et al
    Alzheimer's disease neuropathological change three decades after iatrogenic amyloid-beta transmission.
    Acta Neuropathol. 2021 May 28. pii: 10.1007/s00401-021-02326.
    PubMed    


  79. DAVE N, Vural AS, Piras IS, Winslow W, et al
    Identification of retinoblastoma binding protein 7 (Rbbp7) as a mediator against tau acetylation and subsequent neuronal loss in Alzheimer's disease and related tauopathies.
    Acta Neuropathol. 2021 May 12. pii: 10.1007/s00401-021-02323.
    PubMed     Abstract available


  80. GARCIA-ESCUDERO V, Ruiz-Gabarre D, Gargini R, Perez M, et al
    A new non-aggregative splicing isoform of human Tau is decreased in Alzheimer's disease.
    Acta Neuropathol. 2021 May 2. pii: 10.1007/s00401-021-02317.
    PubMed     Abstract available


    April 2021
  81. KANG SS, Ahn EH, Liu X, Bryson M, et al
    ApoE4 inhibition of VMAT2 in the locus coeruleus exacerbates Tau pathology in Alzheimer's disease.
    Acta Neuropathol. 2021 Apr 25. pii: 10.1007/s00401-021-02315.
    PubMed     Abstract available


  82. VALVERDE A, Dunys J, Lorivel T, Debayle D, et al
    Aminopeptidase A contributes to biochemical, anatomical and cognitive defects in Alzheimer's disease (AD) mouse model and is increased at early stage in sporadic AD brain.
    Acta Neuropathol. 2021 Apr 21. pii: 10.1007/s00401-021-02308.
    PubMed     Abstract available


  83. SHI Y, Murzin AG, Falcon B, Epstein A, et al
    Correction to: Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
    Acta Neuropathol. 2021 Apr 8. pii: 10.1007/s00401-021-02303.
    PubMed    


  84. TOME SO, Gomes LA, Li X, Vandenberghe R, et al
    TDP-43 interacts with pathological tau protein in Alzheimer's disease.
    Acta Neuropathol. 2021 Apr 2. pii: 10.1007/s00401-021-02295.
    PubMed    


    March 2021
  85. SHI Y, Murzin AG, Falcon B, Epstein A, et al
    Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
    Acta Neuropathol. 2021 Mar 16. pii: 10.1007/s00401-021-02294.
    PubMed     Abstract available


    February 2021
  86. GERRITS E, Brouwer N, Kooistra SM, Woodbury ME, et al
    Distinct amyloid-beta and tau-associated microglia profiles in Alzheimer's disease.
    Acta Neuropathol. 2021 Feb 20. pii: 10.1007/s00401-021-02263.
    PubMed     Abstract available


  87. CACACE R, Van Broeckhoven C
    Reply: Lack of evidence supporting a role for DPP6 sequence variants in Alzheimer's disease in the European American population.
    Acta Neuropathol. 2021 Feb 16. pii: 10.1007/s00401-021-02277.
    PubMed    


  88. KIROLA L, Budde JP, Wang F, Norton J, et al
    Lack of evidence supporting a role for DPP6 sequence variants in Alzheimer's disease in the European American population.
    Acta Neuropathol. 2021 Feb 16. pii: 10.1007/s00401-021-02271.
    PubMed    


  89. ASHTON NJ, Pascoal TA, Karikari TK, Benedet AL, et al
    Plasma p-tau231: a new biomarker for incipient Alzheimer's disease pathology.
    Acta Neuropathol. 2021 Feb 14. pii: 10.1007/s00401-021-02275.
    PubMed     Abstract available


  90. ARAGAO GOMES L, Uytterhoeven V, Lopez-Sanmartin D, Tome SO, et al
    Maturation of neuronal AD-tau pathology involves site-specific phosphorylation of cytoplasmic and synaptic tau preceding conformational change and fibril formation.
    Acta Neuropathol. 2021;141:173-192.
    PubMed     Abstract available


  91. XU H, O'Reilly M, Gibbons GS, Changolkar L, et al
    In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics.
    Acta Neuropathol. 2021;141:193-215.
    PubMed     Abstract available


    January 2021
  92. HONDIUS DC, Koopmans F, Leistner C, Pita-Illobre D, et al
    The proteome of granulovacuolar degeneration and neurofibrillary tangles in Alzheimer's disease.
    Acta Neuropathol. 2021 Jan 25. pii: 10.1007/s00401-020-02261.
    PubMed     Abstract available


  93. MATCHETT BJ, Grinberg LT, Theofilas P, Murray ME, et al
    The mechanistic link between selective vulnerability of the locus coeruleus and neurodegeneration in Alzheimer's disease.
    Acta Neuropathol. 2021 Jan 11. pii: 10.1007/s00401-020-02248.
    PubMed     Abstract available


    December 2020
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