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Articles published in Acta Neuropathol

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Single Articles


    November 2018
  1. MOLINUEVO JL, Ayton S, Batrla R, Bednar MM, et al
    Current state of Alzheimer's fluid biomarkers.
    Acta Neuropathol. 2018 Nov 28. pii: 10.1007/s00401-018-1932.
    PubMed     Text format     Abstract available


  2. FROSCH MP
    "When sex influences the brain: implications for Alzheimer disease".
    Acta Neuropathol. 2018 Nov 15. pii: 10.1007/s00401-018-1931.
    PubMed     Text format    


  3. WALTER S, Jumpertz T, Huttenrauch M, Ogorek I, et al
    The metalloprotease ADAMTS4 generates N-truncated Abeta4-x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer's disease.
    Acta Neuropathol. 2018 Nov 13. pii: 10.1007/s00401-018-1929.
    PubMed     Text format     Abstract available


  4. BROCE IJ, Tan CH, Fan CC, Jansen I, et al
    Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease.
    Acta Neuropathol. 2018 Nov 9. pii: 10.1007/s00401-018-1928.
    PubMed     Text format     Abstract available


    October 2018
  5. MORRIS GP, Clark IA, Vissel B
    Questions concerning the role of amyloid-beta in the definition, aetiology and diagnosis of Alzheimer's disease.
    Acta Neuropathol. 2018 Oct 22. pii: 10.1007/s00401-018-1918.
    PubMed     Text format     Abstract available


  6. OVEISGHARAN S, Arvanitakis Z, Yu L, Farfel J, et al
    Sex differences in Alzheimer's disease and common neuropathologies of aging.
    Acta Neuropathol. 2018 Oct 17. pii: 10.1007/s00401-018-1920.
    PubMed     Text format     Abstract available


  7. FALCON B, Zhang W, Schweighauser M, Murzin AG, et al
    Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
    Acta Neuropathol. 2018 Oct 1. pii: 10.1007/s00401-018-1914.
    PubMed     Text format     Abstract available


    September 2018
  8. KVARTSBERG H, Lashley T, Murray CE, Brinkmalm G, et al
    The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer's disease.
    Acta Neuropathol. 2018 Sep 22. pii: 10.1007/s00401-018-1910.
    PubMed     Text format     Abstract available


  9. COURADE JP, Angers R, Mairet-Coello G, Pacico N, et al
    Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau.
    Acta Neuropathol. 2018 Sep 20. pii: 10.1007/s00401-018-1911.
    PubMed     Text format     Abstract available


  10. LIESINGER AM, Graff-Radford NR, Duara R, Carter RE, et al
    Sex and age interact to determine clinicopathologic differences in Alzheimer's disease.
    Acta Neuropathol. 2018 Sep 15. pii: 10.1007/s00401-018-1908.
    PubMed     Text format     Abstract available


  11. PICKETT EK, Rose J, McCrory C, McKenzie CA, et al
    Region-specific depletion of synaptic mitochondria in the brains of patients with Alzheimer's disease.
    Acta Neuropathol. 2018 Sep 6. pii: 10.1007/s00401-018-1903.
    PubMed     Text format     Abstract available


    August 2018
  12. JELLINGER KA
    Different patterns of hippocampal tau pathology in Alzheimer's disease and PART.
    Acta Neuropathol. 2018 Aug 7. pii: 10.1007/s00401-018-1894.
    PubMed     Text format    


    July 2018
  13. HEINSEN H, Grinberg LT
    On the origin of tau seeding activity in Alzheimer's disease.
    Acta Neuropathol. 2018 Jul 23. pii: 10.1007/s00401-018-1890.
    PubMed     Text format    


  14. KHAN SS, LaCroix M, Boyle G, Sherman MA, et al
    Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons.
    Acta Neuropathol. 2018 Jul 11. pii: 10.1007/s00401-018-1886.
    PubMed     Text format     Abstract available


  15. DEMING Y, Dumitrescu L, Barnes LL, Thambisetty M, et al
    Sex-specific genetic predictors of Alzheimer's disease biomarkers.
    Acta Neuropathol. 2018 Jul 2. pii: 10.1007/s00401-018-1881.
    PubMed     Text format     Abstract available


  16. SARDAR SINHA M, Ansell-Schultz A, Civitelli L, Hildesjo C, et al
    Alzheimer's disease pathology propagation by exosomes containing toxic amyloid-beta oligomers.
    Acta Neuropathol. 2018;136:41-56.
    PubMed     Text format     Abstract available


    June 2018
  17. ROBINSON JL, Corrada MM, Kovacs GG, Dominique M, et al
    Non-Alzheimer's contributions to dementia and cognitive resilience in The 90+ Study.
    Acta Neuropathol. 2018 Jun 18. pii: 10.1007/s00401-018-1872.
    PubMed     Text format     Abstract available


    May 2018
  18. MANN DMA, Davidson YS, Robinson AC, Allen N, et al
    Patterns and severity of vascular amyloid in Alzheimer's disease associated with duplications and missense mutations in APP gene, Down syndrome and sporadic Alzheimer's disease.
    Acta Neuropathol. 2018 May 16. pii: 10.1007/s00401-018-1866.
    PubMed     Text format     Abstract available


  19. KAUFMAN SK, Del Tredici K, Thomas TL, Braak H, et al
    Tau seeding activity begins in the transentorhinal/entorhinal regions and anticipates phospho-tau pathology in Alzheimer's disease and PART.
    Acta Neuropathol. 2018 May 11. pii: 10.1007/s00401-018-1855.
    PubMed     Text format     Abstract available


    April 2018
  20. ANDROUIN A, Potier B, Nagerl UV, Cattaert D, et al
    Evidence for altered dendritic spine compartmentalization in Alzheimer's disease and functional effects in a mouse model.
    Acta Neuropathol. 2018 Apr 25. pii: 10.1007/s00401-018-1847.
    PubMed     Text format     Abstract available


  21. HONG W, Wang Z, Liu W, O'Malley TT, et al
    Diffusible, highly bioactive oligomers represent a critical minority of soluble Abeta in Alzheimer's disease brain.
    Acta Neuropathol. 2018 Apr 23. pii: 10.1007/s00401-018-1846.
    PubMed     Text format     Abstract available


    March 2018
  22. DE ROECK A, Duchateau L, Van Dongen J, Cacace R, et al
    An intronic VNTR affects splicing of ABCA7 and increases risk of Alzheimer's disease.
    Acta Neuropathol. 2018 Mar 27. pii: 10.1007/s00401-018-1841.
    PubMed     Text format     Abstract available


  23. HECHT M, Kramer LM, von Arnim CAF, Otto M, et al
    Capillary cerebral amyloid angiopathy in Alzheimer's disease: association with allocortical/hippocampal microinfarcts and cognitive decline.
    Acta Neuropathol. 2018 Mar 24. pii: 10.1007/s00401-018-1834.
    PubMed     Text format     Abstract available


    November 2017
  24. TAN CH, Fan CC, Mormino EC, Sugrue LP, et al
    Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition.
    Acta Neuropathol. 2017 Nov 24. pii: 10.1007/s00401-017-1789.
    PubMed     Text format     Abstract available


    June 2017
  25. MCALEESE KE, Walker L, Graham S, Moya ELJ, et al
    Parietal white matter lesions in Alzheimer's disease are associated with cortical neurodegenerative pathology, but not with small vessel disease.
    Acta Neuropathol. 2017 Jun 21. doi: 10.1007/s00401-017-1738.
    PubMed     Text format     Abstract available


  26. LACAMPAGNE A, Liu X, Reiken S, Bussiere R, et al
    Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.
    Acta Neuropathol. 2017 Jun 19. doi: 10.1007/s00401-017-1733.
    PubMed     Text format     Abstract available


  27. HAURE-MIRANDE JV, Audrain M, Fanutza T, Kim SH, et al
    Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer's pathology.
    Acta Neuropathol. 2017 Jun 13. doi: 10.1007/s00401-017-1737.
    PubMed     Text format     Abstract available


    May 2017
  28. JIN WS, Shen LL, Bu XL, Zhang WW, et al
    Peritoneal dialysis reduces amyloid-beta plasma levels in humans and attenuates Alzheimer-associated phenotypes in an APP/PS1 mouse model.
    Acta Neuropathol. 2017 May 5. doi: 10.1007/s00401-017-1721.
    PubMed     Text format     Abstract available


  29. PASCUAL G, Wadia JS, Zhu X, Keogh E, et al
    Immunological memory to hyperphosphorylated tau in asymptomatic individuals.
    Acta Neuropathol. 2017;133:767-783.
    PubMed     Text format     Abstract available


  30. TAKAHASHI H, Klein ZA, Bhagat SM, Kaufman AC, et al
    Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network.
    Acta Neuropathol. 2017;133:785-807.
    PubMed     Text format     Abstract available


    April 2017
  31. DE ROECK A, Van den Bossche T, van der Zee J, Verheijen J, et al
    Deleterious ABCA7 mutations and transcript rescue mechanisms in early onset Alzheimer's disease.
    Acta Neuropathol. 2017 Apr 27. doi: 10.1007/s00401-017-1714.
    PubMed     Text format     Abstract available


    March 2017
  32. DURAN-ANIOTZ C, Cornejo VH, Espinoza S, Ardiles AO, et al
    IRE1 signaling exacerbates Alzheimer's disease pathogenesis.
    Acta Neuropathol. 2017 Mar 24. doi: 10.1007/s00401-017-1694.
    PubMed     Text format     Abstract available


  33. SUN M, Bell W, LaClair KD, Ling JP, et al
    Cryptic exon incorporation occurs in Alzheimer's brain lacking TDP-43 inclusion but exhibiting nuclear clearance of TDP-43.
    Acta Neuropathol. 2017 Mar 22. doi: 10.1007/s00401-017-1701.
    PubMed     Text format     Abstract available


  34. DRUMMOND E, Nayak S, Faustin A, Pires G, et al
    Proteomic differences in amyloid plaques in rapidly progressive and sporadic Alzheimer's disease.
    Acta Neuropathol. 2017 Mar 4. doi: 10.1007/s00401-017-1691.
    PubMed     Text format     Abstract available


    February 2017
  35. DEMING Y, Li Z, Kapoor M, Harari O, et al
    Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.
    Acta Neuropathol. 2017 Feb 28. doi: 10.1007/s00401-017-1685.
    PubMed     Text format     Abstract available


    January 2017
  36. ZENG J, Chen L, Wang Z, Chen Q, et al
    Marginal vitamin A deficiency facilitates Alzheimer's pathogenesis.
    Acta Neuropathol. 2017 Jan 27. doi: 10.1007/s00401-017-1669.
    PubMed     Text format     Abstract available


  37. FURMAN JL, Vaquer-Alicea J, White CL 3rd, Cairns NJ, et al
    Widespread tau seeding activity at early Braak stages.
    Acta Neuropathol. 2017;133:91-100.
    PubMed     Text format     Abstract available


  38. JAN A, Jansonius B, Delaidelli A, Somasekharan SP, et al
    eEF2K inhibition blocks Abeta42 neurotoxicity by promoting an NRF2 antioxidant response.
    Acta Neuropathol. 2017;133:101-119.
    PubMed     Text format     Abstract available


    December 2016
  39. DRUMMOND E, Wisniewski T
    Alzheimer's disease: experimental models and reality.
    Acta Neuropathol. 2016 Dec 26. doi: 10.1007/s00401-016-1662.
    PubMed     Text format     Abstract available


  40. CHAPUIS J, Flaig A, Grenier-Boley B, Eysert F, et al
    Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


    November 2016
  41. RAMOS-MIGUEL A, Sawada K, Jones AA, Thornton AE, et al
    Presynaptic proteins complexin-I and complexin-II differentially influence cognitive function in early and late stages of Alzheimer's disease.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


    October 2016
  42. LACLAIR KD, Donde A, Ling JP, Jeong YH, et al
    Depletion of TDP-43 decreases fibril and plaque beta-amyloid and exacerbates neurodegeneration in an Alzheimer's mouse model.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


  43. KOSS DJ, Jones G, Cranston A, Gardner H, et al
    Soluble pre-fibrillar tau and beta-amyloid species emerge in early human Alzheimer's disease and track disease progression and cognitive decline.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


  44. SANCHEZ-MEJIAS E, Navarro V, Jimenez S, Sanchez-Mico M, et al
    Soluble phospho-tau from Alzheimer's disease hippocampus drives microglial degeneration.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


    September 2016
  45. HART NJ, Koronyo Y, Black KL, Koronyo-Hamaoui M, et al
    Ocular indicators of Alzheimer's: exploring disease in the retina.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


  46. ANDERSEN OM, Rudolph IM, Willnow TE
    Risk factor SORL1: from genetic association to functional validation in Alzheimer's disease.
    Acta Neuropathol. 2016.
    PubMed     Text format     Abstract available


    April 2016
  47. KUMAR S, Wirths O, Stuber K, Wunderlich P, et al
    Phosphorylation of the amyloid beta-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity.
    Acta Neuropathol. 2016;131:525-37.
    PubMed     Text format     Abstract available


    January 2016
  48. EISELE YS, Duyckaerts C
    Propagation of Ass pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies.
    Acta Neuropathol. 2016;131:5-25.
    PubMed     Text format     Abstract available


  49. MCKEE AC, Cairns NJ, Dickson DW, Folkerth RD, et al
    The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy.
    Acta Neuropathol. 2016;131:75-86.
    PubMed     Text format     Abstract available


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