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  Alzheimer's Disease

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22.07.2024

1 Acta Neuropathol
19 Alzheimers Dement
2 Am J Geriatr Psychiatry
1 BMC Geriatr
1 BMJ
3 Brain
5 Curr Alzheimer Res
1 Exp Neurol
9 J Alzheimers Dis
1 J Am Geriatr Soc
3 J Neurochem
1 J Neurol Neurosurg Psychiatry
1 Lancet Neurol
2 Nat Med
3 Neurobiol Aging
2 Neurobiol Dis
1 Neurochem Res
1 Neuroscience
3 PLoS One


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Acta Neuropathol

  1. KASRI A, Camporesi E, Gkanatsiou E, Boluda S, et al
    Amyloid-beta peptide signature associated with cerebral amyloid angiopathy in familial Alzheimer's disease with APPdup and Down syndrome.
    Acta Neuropathol. 2024;148:8.
    PubMed         Abstract available


    Alzheimers Dement

  2. DEAN HB, Greer RA, Yang SZ, Elston DS, et al
    Multimerization of TREM2 is impaired by Alzheimer's disease-associated variants.
    Alzheimers Dement. 2024 Jul 20. doi: 10.1002/alz.14124.
    PubMed         Abstract available

  3. WARMENHOVEN N, Sanchez-Benavides G, Gonzalez-Escalante A, Mila-Aloma M, et al
    CSF glial biomarkers are associated with cognition in individuals at risk of Alzheimer's disease.
    Alzheimers Dement. 2024 Jul 19. doi: 10.1002/alz.13862.
    PubMed         Abstract available

  4. WANG G, Cutter G, Oxtoby NP, Shan G, et al
    Statistical considerations when estimating time-saving treatment effects in Alzheimer's disease clinical trials.
    Alzheimers Dement. 2024 Jun 21. doi: 10.1002/alz.14035.
    PubMed         Abstract available

  5. BECKMAN D, Diniz GB, Ott S, Hobson B, et al
    Temporal progression of tau pathology and neuroinflammation in a rhesus monkey model of Alzheimer's disease.
    Alzheimers Dement. 2024 Jun 21. doi: 10.1002/alz.13868.
    PubMed         Abstract available

  6. MORALES J, Gabriel N, Natarajan L, LaCroix AZ, et al
    Pharmacoepidemiology evaluation of bumetanide as a potential candidate for drug repurposing for Alzheimer's disease.
    Alzheimers Dement. 2024 Jun 21. doi: 10.1002/alz.13872.
    PubMed         Abstract available

  7. GE YJ, Chen SD, Wu BS, Zhang YR, et al
    Genome-wide meta-analysis identifies ancestry-specific loci for Alzheimer's disease.
    Alzheimers Dement. 2024 Jul 18. doi: 10.1002/alz.14121.
    PubMed         Abstract available

  8. LANSDALL CJ, Teng E, Chague J, Palanganda R, et al
    Care partner-informed meaningful change thresholds for the Clinical Dementia Rating-Sum of Boxes for trials of early Alzheimer's disease.
    Alzheimers Dement. 2024 Jul 17. doi: 10.1002/alz.14050.
    PubMed         Abstract available

  9. ZHANG C, Jia Q, Zhu L, Hou J, et al
    Suppressing UBE2N ameliorates Alzheimer's disease pathology through the clearance of amyloid beta.
    Alzheimers Dement. 2024 Jul 17. doi: 10.1002/alz.14122.
    PubMed         Abstract available

  10. WIESMAN AI, Gallego-Rudolf J, Villeneuve S, Baillet S, et al
    Neurochemical organization of cortical proteinopathy and neurophysiology along the Alzheimer's disease continuum.
    Alzheimers Dement. 2024 Jul 12. doi: 10.1002/alz.14110.
    PubMed         Abstract available

  11. UEKAWA K, Anfray A, Ahn SJ, Casey N, et al
    tPA supplementation preserves neurovascular and cognitive function in Tg2576 mice.
    Alzheimers Dement. 2024;20:4572-4582.
    PubMed         Abstract available

  12. SINGH NA, Alnobani A, Graff-Radford J, Machulda MM, et al
    Relationships between PET and blood plasma biomarkers in corticobasal syndrome.
    Alzheimers Dement. 2024;20:4765-4774.
    PubMed         Abstract available

  13. HEYWOOD A, Stocks J, Schneider JA, Arfanakis K, et al
    In vivo effect of LATE-NC on integrity of white matter connections to the hippocampus.
    Alzheimers Dement. 2024;20:4401-4410.
    PubMed         Abstract available

  14. LLAMAS RODRIGUEZ J, van der Kouwe AJW, Oltmer J, Rosenblum E, et al
    Entorhinal vessel density correlates with phosphorylated tau and TDP-43 pathology.
    Alzheimers Dement. 2024;20:4649-4662.
    PubMed         Abstract available

  15. GONZALEZ-BAUTISTA E, Mommeja M, de Mauleon A, Ismail Z, et al
    Mild behavioral impairment domains are longitudinally associated with pTAU and metabolic biomarkers in dementia-free older adults.
    Alzheimers Dement. 2024;20:4692-4701.
    PubMed         Abstract available

  16. HUPER L, Steinacker P, Polyakova M, Mueller K, et al
    Neurofilaments and progranulin are related to atrophy in frontotemporal lobar degeneration - A transdiagnostic study cross-validating atrophy and fluid biomarkers.
    Alzheimers Dement. 2024;20:4461-4475.
    PubMed         Abstract available

  17. ONOS KD, Lin PB, Pandey RS, Persohn SA, et al
    Assessment of neurovascular uncoupling: APOE status is a key driver of early metabolic and vascular dysfunction.
    Alzheimers Dement. 2024;20:4951-4969.
    PubMed         Abstract available

  18. DUNHAM SJB, Avelar-Barragan J, Rothman JA, Adams ED, et al
    Sex-specific associations between AD genotype and the microbiome of human amyloid beta knock-in (hAbeta-KI) mice.
    Alzheimers Dement. 2024;20:4935-4950.
    PubMed         Abstract available

  19. BUTLER CA, Mendoza Arvilla A, Milinkeviciute G, Da Cunha C, et al
    The Abca7(V1613M) variant reduces Abeta generation, plaque load, and neuronal damage.
    Alzheimers Dement. 2024;20:4914-4934.
    PubMed         Abstract available

  20. CHAKRABARTY M, Klooster N, Biswas A, Chatterjee A, et al
    The scope of using pragmatic language tests for early detection of dementia: A systematic review of investigations using figurative language.
    Alzheimers Dement. 2023;19:4705-4728.
    PubMed         Abstract available


    Am J Geriatr Psychiatry

  21. ZANDBAGLEH A, Miltiadous A, Sanei S, Azami H, et al
    Beta-to-Theta Entropy Ratio of EEG in Aging, Frontotemporal Dementia, and Alzheimer's Dementia.
    Am J Geriatr Psychiatry. 2024 Jul 4:S1064-7481(24)00380.
    PubMed         Abstract available

  22. ZHU CW, Schneider LS, Elder GA, Soleimani L, et al
    Neuropsychiatric Symptom Profile in Alzheimer's Disease and Their Relationship With Functional Decline.
    Am J Geriatr Psychiatry. 2024 Jun 29:S1064-7481(24)00375.
    PubMed         Abstract available


    BMC Geriatr

  23. GUMIKIRIZA-ONORIA JL, Nakigudde J, Mayega RW, Giordani B, et al
    Psychological distress among family caregivers of persons with Alzheimer's disease and related dementias in Uganda.
    BMC Geriatr. 2024;24:602.
    PubMed         Abstract available


    BMJ

  24. DYER O
    Scientist who worked on Cassava's Alzheimer drug simufilam charged with fraud.
    BMJ. 2024;386:q1568.
    PubMed        


    Brain

  25. MATTSSON-CARLGREN N
    Disentangling genetic risks for development and progression of Alzheimer's disease.
    Brain. 2024 Jul 18:awae237. doi: 10.1093.
    PubMed        

  26. APPLETON J, Finn Q, Zanotti-Fregonara P, Yu M, et al
    Brain inflammation co-localizes highly with tau in mild cognitive impairment due to early-onset Alzheimer's disease.
    Brain. 2024 Jul 16:awae234. doi: 10.1093.
    PubMed         Abstract available

  27. CAI H, Zhao T, Pang Y, Fu X, et al
    Systemic inflammatory markers in ageing, Alzheimer's disease and other dementias.
    Brain. 2024 Jul 15:awae230. doi: 10.1093.
    PubMed         Abstract available


    Curr Alzheimer Res

  28. SAEZ JMG
    Drive My CAR-AD Research here, there and Everywhere.
    Curr Alzheimer Res. 2024;21:1-2.
    PubMed        

  29. KUSHWAH S, Mani A
    Comprehensive Investigation of Natural Ligands as Inhibitors of beta Secretase to Identify Alzheimer's Disease Therapeutics.
    Curr Alzheimer Res. 2024 Jul 15. doi: 10.2174/0115672050323622240705043337.
    PubMed         Abstract available

  30. SCARFO S, Moshfeghi Y, J McGeown W
    Assessing the Stability of Clusters of Neuropsychiatric Symptoms in Alzheimer's Disease and Mild Cognitive Impairment.
    Curr Alzheimer Res. 2024 Jul 15. doi: 10.2174/0115672050309014240705113444.
    PubMed         Abstract available

  31. PADALA S, Setti S, Raymick J, Hanig J, et al
    Evaluation and Characterization of Modified K114 Method to Localize Plaques in Rodent and Plaques and Tangles in Human Brain Tissue.
    Curr Alzheimer Res. 2024;21:69-80.
    PubMed         Abstract available

  32. BENTLEY JH, Broussard JI
    Multimodal Gamma Stimulation Improves Activity but not Memory in Aged Tgf344-AD Rats.
    Curr Alzheimer Res. 2024;20:769-777.
    PubMed         Abstract available


    Exp Neurol

  33. ZHAO Y, He C, Hu S, Ni H, et al
    Anti-oxidative stress and cognitive improvement of a semi-synthetic isoorientin-based GSK-3beta inhibitor in rat pheochromocytoma cell PC12 and scopolamine-induced AD model mice via AKT/GSK-3beta/Nrf2 pathway.
    Exp Neurol. 2024 Jul 10:114881. doi: 10.1016/j.expneurol.2024.114881.
    PubMed         Abstract available


    J Alzheimers Dis


  34. Robert Rissman, PhD, is the recipient of the 2024 Alzheimer Award.
    J Alzheimers Dis. 2024;100:377-378.
    PubMed        

  35. BUTTERFIELD DA
    Activation of the Neuronal Cell Cycle in Brains in Amnestic Mild Cognitive Impairment: Early Involvement in the Progression of Alzheimer's Disease.
    J Alzheimers Dis. 2024 Jul 12. doi: 10.3233/JAD-240615.
    PubMed         Abstract available

  36. MANDAL PK, Maroon JC, Samkaria A, Arora Y, et al
    Iron Chelators and Alzheimer's Disease Clinical Trials.
    J Alzheimers Dis. 2024 Jul 12. doi: 10.3233/JAD-240605.
    PubMed         Abstract available

  37. AMARAL-CARVALHO V, Bento Lima-Silva T, Inacio Mariano L, Cruz de Souza L, et al
    Improved Accuracy of the Addenbrooke's Cognitive Examination-Revised in the Diagnosis of Mild Cognitive Impairment, Mild Dementia Due to Alzheimer's Disease and Behavioral Variant Frontotemporal Dementia Using Mokken Scale Analysis.
    J Alzheimers Dis. 2024 Jul 12. doi: 10.3233/JAD-240554.
    PubMed         Abstract available

  38. WANG RT, Sun Z, Tan CC, Tan L, et al
    Dynamic Features of Body Mass Index in Late Life Predict Cognitive Trajectories and Alzheimer's Disease: A Longitudinal Study.
    J Alzheimers Dis. 2024 Jul 12. doi: 10.3233/JAD-240292.
    PubMed         Abstract available

  39. KRIZANOVIC N, Jokisch M, Jockel KH, Schmidt B, et al
    Sex-Specific Differences in Serum Kallikrein-8 (KLK8): An Exploratory Study.
    J Alzheimers Dis. 2024;100:495-507.
    PubMed         Abstract available

  40. HOWARD E, Moody JN, Prieto S, Hayes JP, et al
    Higher Cerebrospinal Fluid Levels of Amyloid-beta40 Following Traumatic Brain Injury Relate to Confrontation Naming Performance.
    J Alzheimers Dis. 2024;100:539-550.
    PubMed         Abstract available

  41. HE Q, Wang W, Xiong Y, Tao C, et al
    Potential Biomarkers in Cerebrospinal Fluid and Plasma for Dementia.
    J Alzheimers Dis. 2024;100:603-611.
    PubMed         Abstract available

  42. LOEFFLER DA
    Approaches for Increasing Cerebral Efflux of Amyloid-beta in Experimental Systems.
    J Alzheimers Dis. 2024;100:379-411.
    PubMed         Abstract available


    J Am Geriatr Soc

  43. DUONG MT
    Living art and Giving art in Alzheimer disease.
    J Am Geriatr Soc. 2024 Jul 17. doi: 10.1111/jgs.19101.
    PubMed        


    J Neurochem

  44. DEN HOEDT S, Crivelli SM, Dorst-Lagerwerf KY, Leijten FPJ, et al
    The effects of APOE4 and familial Alzheimer's disease mutations on free fatty acid profiles in mouse brain are age- and sex-dependent.
    J Neurochem. 2024 Jul 13. doi: 10.1111/jnc.16176.
    PubMed         Abstract available

  45. HUANG HX, Inglese P, Tang J, Yagoubi R, et al
    Mass spectrometry imaging highlights dynamic patterns of lipid co-expression with Abeta plaques in mouse and human brains.
    J Neurochem. 2024;168:1193-1214.
    PubMed         Abstract available

  46. VAN DEN BERG E, Kersten I, Brinkmalm G, Johansson K, et al
    Profiling amyloid-beta peptides as biomarkers for cerebral amyloid angiopathy.
    J Neurochem. 2024;168:1254-1264.
    PubMed         Abstract available


    J Neurol Neurosurg Psychiatry

  47. MATSUOKA T, Oya N, Narumoto J, Kitani-Morii F, et al
    Reduced pineal volume may be associated with amyloid pathology and not with putative Lewy body pathology.
    J Neurol Neurosurg Psychiatry. 2024;95:791-792.
    PubMed        


    Lancet Neurol

  48. OHRY A
    Ezio Giacobini: a leader in Alzheimer's disease research.
    Lancet Neurol. 2024;23:768.
    PubMed        


    Nat Med

  49. PAPPALETTERA C, Carrarini C, Cappa S, Caraglia N, et al
    Challenges to identifying risk versus protective factors in Alzheimer's disease.
    Nat Med. 2024 Jul 18. doi: 10.1038/s41591-024-03158.
    PubMed        

  50. FORTEA J, Vaque-Alcazar L, Pegueroles J, Alcolea D, et al
    Reply to: Challenges to identifying risk versus protective factors in Alzheimer's disease.
    Nat Med. 2024 Jul 18. doi: 10.1038/s41591-024-03159.
    PubMed        


    Neurobiol Aging

  51. KARIM HT, Lee S, Gerlach A, Stinley M, et al
    Hippocampal subfield volume in older adults with and without mild cognitive impairment: Effects of worry and cognitive reappraisal.
    Neurobiol Aging. 2024;141:55-65.
    PubMed         Abstract available

  52. JIMENEZ-BALADO J, Habeck C, Stern Y, Eich T, et al
    The relationship between cortical thickness and white matter hyperintensities in mid to late life.
    Neurobiol Aging. 2024;141:129-139.
    PubMed         Abstract available

  53. CHATTERJEE A, Lee S, Diaz V, Saloner R, et al
    Associations of cerebrovascular disease and Alzheimer's disease pathology with cognitive decline: Analysis of the National Alzheimer's Coordinating Center Uniform Data Set.
    Neurobiol Aging. 2024;142:1-7.
    PubMed         Abstract available


    Neurobiol Dis

  54. BUCHANAN RA, Wang Y, May JM, Harrison FE, et al
    Ascorbate insufficiency disrupts glutamatergic signaling and alters electroencephalogram phenotypes in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2024 Jul 12:106602. doi: 10.1016/j.nbd.2024.106602.
    PubMed         Abstract available

  55. LOPEZ-CERDAN A, Andreu Z, Hidalgo MR, Soler-Saez I, et al
    An integrated approach to identifying sex-specific genes, transcription factors, and pathways relevant to Alzheimer's disease.
    Neurobiol Dis. 2024;199:106605.
    PubMed         Abstract available


    Neurochem Res

  56. LUO JS, Zhai WH, Ding LL, Zhang XJ, et al
    MAMs and Mitochondrial Quality Control: Overview and Their Role in Alzheimer's Disease.
    Neurochem Res. 2024 Jul 13. doi: 10.1007/s11064-024-04205.
    PubMed         Abstract available


    Neuroscience

  57. XIANG LY, Chen XY, Lu LM, Kong MH, et al
    Mechanisms of Neuronal Reactivation in Memory Consolidation: A Perspective from Pathological Conditions.
    Neuroscience. 2024;551:196-204.
    PubMed         Abstract available


    PLoS One


  58. Retraction: Silencing GADD153/CHOP Gene Expression Protects against Alzheimer's Disease-Like Pathology Induced by 27-Hydroxycholesterol in Rabbit Hippocampus.
    PLoS One. 2024;19:e0307751.
    PubMed        

  59. LUO S, Guo L, Chen N, Guo Q, et al
    CRY2 mediates the cognitive decline induced by sleep deprivation in 5xFAD mice.
    PLoS One. 2024;19:e0306930.
    PubMed         Abstract available

  60. KELEMEN L, Gupta I, Yavarow Z, Smith SI, et al
    Clinician's perspectives on gene therapy for Alzheimer's disease: A qualitative study.
    PLoS One. 2024;19:e0307567.
    PubMed         Abstract available


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