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27.04.2026

1 Acta Neuropathol
17 Alzheimers Dement
1 Biochemistry
1 BMJ
1 Brain
1 Brain Res
6 Exp Neurol
17 J Alzheimers Dis
2 J Biol Chem
1 J Neurochem
1 J Neurol
1 Nat Neurosci
1 Neuropsychology
1 Neuroscience
4 PLoS One
1 Proc Natl Acad Sci U S A
1 Science


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Acta Neuropathol

  1. YUAN S, Essepian N, Roberts R, Sherman E, et al
    Tau oligomerization induces nuclear lamina invagination and chromatin remodeling in Alzheimer's disease.
    Acta Neuropathol. 2026;151:43.
    PubMed         Abstract available


    Alzheimers Dement

  2. NG B, Kodosaki E, Veleva E, Keshavan A, et al
    Aging-related matrix metallopeptidase 10 and osteopontin levels are associated with pathology, cognitive decline, and age at onset in Alzheimer's disease.
    Alzheimers Dement. 2026;22:e71082.
    PubMed         Abstract available

  3. GABB VG, Blackman J, Morrison HD, Turner N, et al
    Mind the gap: obtaining reliable sleep estimates and the diagnostic value of sleep discrepancy in individuals with Alzheimer's disease and Lewy body disease.
    Alzheimers Dement. 2026;22:e71377.
    PubMed         Abstract available

  4. ACARSOY C, Bos D, Mooldijk SS, Ikram MA, et al
    Migraine and the Risk of Dementia in the General Population.
    Alzheimers Dement. 2026;22:e71386.
    PubMed         Abstract available

  5. CHAN CK, Glover CM, Parker M, Grill JD, et al
    Outreach, Recruitment and Engagement Cores of NIA-designated Alzheimer's Disease Research Centers: Current strategies and future directions.
    Alzheimers Dement. 2026;22:e71238.
    PubMed         Abstract available

  6. FURMAN S, Zayou L, Tsourmas KI, Javonillo DI, et al
    Infection of 5xFAD mice with a mouse-adapted SARS-CoV-2 does not alter Alzheimer's disease neuropathology yet induces widespread changes in gene expression across diverse cell types.
    Alzheimers Dement. 2026;22:e71394.
    PubMed         Abstract available

  7. DENG W, Xie Y
    Beyond AUC: Clinical interpretability of depression-MRI-machine learning analyses in Alzheimer's disease.
    Alzheimers Dement. 2026;22:e71435.
    PubMed        

  8. WEARN A, Onuska KM, Shanks HRC, Gaurav R, et al
    Locus coeruleus degeneration is associated with cortical tau deposition and cognitive decline in older adults at familial risk of Alzheimer's disease.
    Alzheimers Dement. 2026;22:e71427.
    PubMed         Abstract available

  9. JAMES TA, Zhao L, Xu H, Wu J, et al
    Visual memory correlates with AD biomarkers in cognitively unimpaired individuals.
    Alzheimers Dement. 2026;22:e71417.
    PubMed         Abstract available

  10. CLARK AL, Hamlin AM
    Life course neighborhood conditions and change: a 20-year examination of neighborhood context and associations with Alzheimer's disease biomarkers in late life.
    Alzheimers Dement. 2026;22:e71382.
    PubMed         Abstract available

  11. MIGEOT J, Wen O, Gonzalez-Gomez R, Hernandez H, et al
    Neural embedding of frailty in cognitively unimpaired aging and dementia across Latin America.
    Alzheimers Dement. 2026;22:e71232.
    PubMed         Abstract available

  12. ARCE RENTERIA M, Strangmann IM, Ghazi Saidi L, Subina MM, et al
    Deconstructing bilingualism and its sociocultural determinants in cognitive aging and Alzheimer's disease and related dementias.
    Alzheimers Dement. 2026;22:e71393.
    PubMed         Abstract available

  13. DOIRON D, Jovanovic Andersen Z, Bozigar M, Habre R, et al
    Integrating the physical environment into Alzheimer's disease and Alzheimer's disease related dementias research: A Gateway Exposome Coordinating Center (GECC) agenda on gaps and priorities.
    Alzheimers Dement. 2026;22:e71429.
    PubMed         Abstract available

  14. VAN ETTEN ES, Mahinrad S, Grill JD, Salloway S, et al
    Amyloid-related imaging abnormalities (ARIA) in anti-amyloid therapies for Alzheimer's disease: An update from the Alzheimer's Association ARIA workgroup.
    Alzheimers Dement. 2026;22:e71361.
    PubMed         Abstract available

  15. GORNIAK-WALAS M, Telugu NS, Rudolph IM, Diecke S, et al
    Alzheimer's disease risk single nucleotide polymorphism rs11218343 is linked to functional expression of SORL1 in microglia.
    Alzheimers Dement. 2026;22:e71390.
    PubMed         Abstract available

  16. SUKREET S, Kim EK, Petersen M, Zhang F, et al
    Precision medicine for Alzheimer's disease in Down syndrome.
    Alzheimers Dement. 2026;22:e71398.
    PubMed         Abstract available

  17. LI R, Langford O, Insel PS, Sperling RA, et al
    Divergent patterns of cognitive decline in preclinical Alzheimer's disease: Implications for secondary prevention trials.
    Alzheimers Dement. 2026;22:e71366.
    PubMed         Abstract available

  18. YANG M, Abdulsalam R, Shi Y, Fan W, et al
    Alzheimer's disease and related dementias and related health conditions among American Indian and Alaska Native Medicare beneficiaries.
    Alzheimers Dement. 2026;22:e71385.
    PubMed         Abstract available


    Biochemistry

  19. WANG T, Sun Y, Lin YR, Yao L, et al
    Controlled Seeding of beta-Amyloid Fibrillation Reveals Propagation of Structural Polymorphisms in Cellular Environments.
    Biochemistry. 2026;65:1261-1269.
    PubMed         Abstract available


    BMJ

  20. NOWELL J, Crook H, de Leon MJ, Edison P, et al
    Advances in the drug treatment of Alzheimer's disease: pathophysiology and mechanisms of action.
    BMJ. 2026;393:78881.
    PubMed         Abstract available


    Brain

  21. CORRIVEAU-LECAVALIER N, Dicks E, Martin PR, Wiste HJ, et al
    Default mode network failure across the Alzheimer's disease spectrum.
    Brain. 2026 Apr 22:awag146. doi: 10.1093.
    PubMed         Abstract available


    Brain Res

  22. SIS CO, Yildiz O, Elci MP, Fatsa T, et al
    Neuroprotective and therapeutic effects of magnesium L-threonate in an amyloid beta(1-42) induced SH-SY5Y cell model of Alzheimer's disease.
    Brain Res. 2026 Apr 21:150341. doi: 10.1016/j.brainres.2026.150341.
    PubMed        


    Exp Neurol

  23. SHI L, Yang J, Guo Y, Wei B, et al
    TRPV1-tau axis: A bidirectional regulatory mechanism linking pain sensitization and Alzheimer's disease progression and its potential for intervention.
    Exp Neurol. 2026 Apr 19:115780. doi: 10.1016/j.expneurol.2026.115780.
    PubMed         Abstract available

  24. CHEN L, Ye Y, Guo X, Li R, et al
    High-intensity interval training and moderate-intensity continuous training improve hippocampal synaptic plasticity in Alzheimer's disease via differential lactylation.
    Exp Neurol. 2026 Apr 16:115782. doi: 10.1016/j.expneurol.2026.115782.
    PubMed         Abstract available

  25. GIANI A, Musi CA, Priori EC, Turchetti S, et al
    Revealing subcellular retinal alterations in 5xFAD B6SJLF1/J mice.
    Exp Neurol. 2026;401:115758.
    PubMed         Abstract available

  26. XUE C, Chen C, Zou X, Li S, et al
    Hippocampal astrocyte St6galnac5 silencing improves spatial memory and preserves synaptic integrity in an AD mouse model.
    Exp Neurol. 2026;401:115742.
    PubMed         Abstract available

  27. OUK K, Fernandez-Klett F, Schormann E, Greiner A, et al
    Rapamycin treatment reduces CD11c(+) microglia and increases amyloid plaque load in 5xFAD mice.
    Exp Neurol. 2026;401:115709.
    PubMed         Abstract available

  28. WANG Y, Gao Q, Shang Z, Li X, et al
    Sulforaphane improved cognitive behavior in APP/PS1 mice via promoting structural and functional synaptic plasticity in the hippocampus.
    Exp Neurol. 2026;401:115727.
    PubMed         Abstract available


    J Alzheimers Dis

  29. SUN Q, Li Y, Wang Y, Tao SS, et al
    Dysbiosis of gut microbiota synergizes with the activation of enteric glial cells to promote Alzheimer's disease.
    J Alzheimers Dis. 2026 Apr 23:13872877261441247. doi: 10.1177/13872877261441247.
    PubMed         Abstract available

  30. SANTOS LTR, Costa FL, Rosa ID, Frota AF, et al
    A metabolic-glial plasma signature defines early Alzheimer's disease: Insights from an understudied cohort.
    J Alzheimers Dis. 2026 Apr 23:13872877261441581. doi: 10.1177/13872877261441581.
    PubMed         Abstract available

  31. RICE M, Willoughby-Dudley KA, Lin M, Wang H, et al
    Differential associations of cognitive screeners with biological, psychological, and cognitive factors in high-risk older adults.
    J Alzheimers Dis. 2026;110:1640-1653.
    PubMed         Abstract available

  32. HAYES CA, Agwu C, Dharmapuri A, Contreras JA, et al
    Contrasting associations of diastolic blood pressure with plasma amyloid, tau, and neurodegeneration biomarkers in the Health and Aging Brain Study-Health Disparities (HABS-HD).
    J Alzheimers Dis. 2026;110:1971-1984.
    PubMed         Abstract available

  33. AGAVRILOAEI LM, Costachescu I, Szilagyi A, Gogu MR, et al
    How amyloid-beta peptide choice shapes neurochemical outcomes in intracerebral rat models of Alzheimer's disease: A systematic review.
    J Alzheimers Dis. 2026 Apr 23:13872877261443555. doi: 10.1177/13872877261443555.
    PubMed         Abstract available

  34. PIZZONI L, Piero AD, Blasutto B, Casagrande M, et al
    Accelerated long-term forgetting in Alzheimer's disease continuum: A systematic review and meta-analysis.
    J Alzheimers Dis. 2026 Apr 23:13872877261443537. doi: 10.1177/13872877261443537.
    PubMed         Abstract available

  35. KERMEL-SCHIFFMAN I, Lifshitz R, Carmel S, Bachner YG, et al
    Attitudes of older adults toward active euthanasia in advanced Alzheimer's disease.
    J Alzheimers Dis. 2026 Apr 23:13872877261444353. doi: 10.1177/13872877261444353.
    PubMed         Abstract available

  36. YE Z, Teng B, Wang S, Zhu J, et al
    Association of inflammation-related plasma proteins with vascular cognitive burden and Alzheimer's disease: A multi-method study.
    J Alzheimers Dis. 2026 Apr 23:13872877261443713. doi: 10.1177/13872877261443713.
    PubMed         Abstract available

  37. LEVINE TF, Mashinchi GM, Rodrigues J, Cross CL, et al
    Effect of sex on trajectories of verbal learning and memory and clinical symptoms in diverse Alzheimer's disease cohorts.
    J Alzheimers Dis. 2026 Apr 23:13872877261444759. doi: 10.1177/13872877261444759.
    PubMed         Abstract available

  38. XIE M, Niu X, Sun F, Shi L, et al
    Transcriptome-based identification and experimental validation of a key gene in Alzheimer's disease using dermal fibroblasts.
    J Alzheimers Dis. 2026 Apr 23:13872877261443968. doi: 10.1177/13872877261443968.
    PubMed         Abstract available

  39. CHUN H, Lee HW, Hong SB, Ha SS, et al
    Home-based transcranial photobiomodulation improves cognitive function in mild cognitive impairment due to Alzheimer's disease: A randomized, double-blind, placebo-controlled confirmatory trial.
    J Alzheimers Dis. 2026 Apr 23:13872877261443973. doi: 10.1177/13872877261443973.
    PubMed         Abstract available

  40. OTTAVIANI S, Bozzo G, De Cesari F, Peruzzo S, et al
    Frailty in early Alzheimer's disease: Complementary clinical value and prognostic significance in biomarker-defined mild cognitive impairment due to Alzheimer's disease.
    J Alzheimers Dis. 2026 Apr 21:13872877261443558. doi: 10.1177/13872877261443558.
    PubMed         Abstract available

  41. HILDEBRANDT H, Duning T, Holland-Letz M
    Is there a cognitive measure of neurodegeneration for amyloid-Abeta-ratio probable Alzheimer's disease patients?
    J Alzheimers Dis. 2026 Apr 21:13872877261444308. doi: 10.1177/13872877261444308.
    PubMed         Abstract available

  42. BHATTACHARJEE S, Choi J, Lee MQ, Kim M, et al
    Electromagnetic field induced activation of amyloid-beta degrading enzyme, neprilysin, for accelerated Alzheimer's disease therapy.
    J Alzheimers Dis. 2026 Apr 21:13872877261444315. doi: 10.1177/13872877261444315.
    PubMed         Abstract available

  43. SANCHEZ-SOBLECHERO A, Puertas-Lopez C, Ibanez-Royo MD, Retuerta-Rodriguez JJ, et al
    Offering and acceptance of plasma p-tau for the diagnosis of Alzheimer's disease: Results and insights from usual practice.
    J Alzheimers Dis. 2026 Apr 21:13872877261443556. doi: 10.1177/13872877261443556.
    PubMed         Abstract available

  44. LIU Y, Shang Z, Wang J, Hou T, et al
    Lipid accumulation product index, serum inflammatory cytokines, and dementia in rural older adults: A population-based study.
    J Alzheimers Dis. 2026;110:1939-1949.
    PubMed         Abstract available

  45. TORUNSKI P, Pizzirusso G, Winblad B, Arroyo-Garcia LE, et al
    Decoding the mechanisms of amyloid-beta in synaptic toxicity.
    J Alzheimers Dis. 2026;110:1560-1583.
    PubMed         Abstract available


    J Biol Chem

  46. ZHANG JY, El Mammeri N, Hong M
    Full-length tau seeded by C-shaped tau fibrils is conformationally variable.
    J Biol Chem. 2026;302:111315.
    PubMed         Abstract available

  47. HTET M, Estay-Olmos C, Hu L, Wu Y, et al
    HEXIM1/P-TEFb complex controls RNA polymerase II pause release and immediate early gene induction following neuronal depolarization.
    J Biol Chem. 2026;302:111325.
    PubMed         Abstract available


    J Neurochem

  48. DURAN-ANIOTZ C, Pizarro M, Migeot J, Salazar-Londono S, et al
    Contextualizing Blood-Based Biomarkers for Dementia Globally.
    J Neurochem. 2026;170:e70443.
    PubMed         Abstract available


    J Neurol

  49. GUO J, Yang Z, Luo S, Li C, et al
    Alzheimer's disease: disrupted communication between the endoplasmic reticulum and mitochondria.
    J Neurol. 2026;273:283.
    PubMed         Abstract available


    Nat Neurosci

  50. NAKAGAWA T, Xie JL, Park K, Cao K, et al
    Early dopamine disruption in the entorhinal cortex of a knock-in model of Alzheimer's disease.
    Nat Neurosci. 2026 Apr 23. doi: 10.1038/s41593-026-02260.
    PubMed         Abstract available


    Neuropsychology

  51. TOSUN S, Karali FS, Eskioglu EI, Cavdar D, et al
    Normative data and clinical validity of verb and phonemic fluency tasks in Turkish-speaking older adults.
    Neuropsychology. 2026;40:418-428.
    PubMed         Abstract available


    Neuroscience

  52. CHU AJ, Erlandsson A, Williams JM
    Amyloid precursor protein derivatives differentially alter the microRNA cargo of astrocyte-derived extracellular vesicles.
    Neuroscience. 2026;603:22-36.
    PubMed         Abstract available


    PLoS One

  53. OU C, Chen B, Deng J, Long H, et al
    Deciphering the molecular network of Trichostatin A in regulating Alzheimer's disease screening of core genes and mechanistic investigation based on multidimensional bioinformatics and molecular simulation.
    PLoS One. 2026;21:e0347532.
    PubMed         Abstract available

  54. AL-ANBARI E, Karshenas H, Shoushtarian B
    Normalizing flow based neural processes for Alzheimer's disease progression prediction.
    PLoS One. 2026;21:e0345958.
    PubMed         Abstract available

  55. ALVI AM, Siuly S, De-Cola MC, Wang H, et al
    CDR-Net: A computerized framework to detect Alzheimer's diseases and mild cognitive impairment.
    PLoS One. 2026;21:e0346576.
    PubMed         Abstract available

  56. KAMIYA M, Osawa A, Otaka E, Kato K, et al
    Correction: Exploring emotion recognition in patients with mild cognitive impairment and Alzheimer's dementia undergoing a rehabilitation program.
    PLoS One. 2026;21:e0347796.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  57. LINDBERG M, Hu J, Thacker D, Sparr E, et al
    The temperature dependence of amyloid beta solubility reveals the hydrophobic effect as the main driving force for fibril formation.
    Proc Natl Acad Sci U S A. 2026;123:e2531916123.
    PubMed         Abstract available


    Science

  58. ZHANG L, Ma Q, Kong X, Zou W, et al
    Mapping transcription factor functions in astrocytes using in vivo gain-of-function Perturb-seq.
    Science. 2026;392:eadw2156.
    PubMed         Abstract available


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