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  Alzheimer's Disease

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16.06.2025

13 Alzheimers Dement
1 Am J Epidemiol
1 BMC Neurol
1 Brain
2 Brain Res
4 Curr Alzheimer Res
1 Dement Geriatr Cogn Disord
2 J Alzheimers Dis
1 J Am Geriatr Soc
1 J Clin Psychiatry
1 JAMA
1 Nat Neurosci
1 Nat Rev Neurol
1 Neurobiol Aging
3 Neurochem Res
1 Neurosci Lett
1 Neuroscience
2 PLoS One


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Alzheimers Dement

  1. VIGNESWARAN S, Vijverberg EGB, Barkhof F, van de Giessen E, et al
    "Real-world" eligibility for anti-amyloid treatment in a tertiary memory clinic setting.
    Alzheimers Dement. 2025;21:e70375.
    PubMed         Abstract available

  2. SAINI F, Ivain P, Idris M, Wells J, et al
    White matter trajectories in Down syndrome and Alzheimer's disease: Insights from diffusion tensor-based morphometry.
    Alzheimers Dement. 2025;21:e70382.
    PubMed         Abstract available

  3. GHISAYS V, Khajouei E, Piras IS, Malek-Ahmadi MH, et al
    Impact of APOE4-related dementia risk in underrepresented groups from the All of Us research program.
    Alzheimers Dement. 2025;21:e70245.
    PubMed         Abstract available

  4. KJAERGAARD D, Nielsen TR, Stomrud E, Palmqvist S, et al
    Influence of ethnicity on the diagnostic accuracy of plasma p-tau217 for the identification of Alzheimer's disease: A consecutive mixed memory clinic cohort study.
    Alzheimers Dement. 2025;21:e70315.
    PubMed         Abstract available

  5. FRUCTUOSO M, Vermeiren Y, Boluda S, Stimmer L, et al
    Disease-specific neuropathological alterations of the locus coeruleus in Alzheimer's disease, Down syndrome, and Parkinson's disease.
    Alzheimers Dement. 2025;21:e70262.
    PubMed         Abstract available

  6. SHI D, Ye C, Li A, Sun P, et al
    Presynaptic loss and axonal degeneration synergistically correlate with longitudinal neurodegeneration and cognitive decline.
    Alzheimers Dement. 2025;21:e70080.
    PubMed         Abstract available

  7. ZHANG M, Hu J, Zhang Y, Meng Z, et al
    Associations between Abeta deposition and neurometabolic alterations in Alzheimer's disease: Insights from hybrid 3D MRSI-PET imaging.
    Alzheimers Dement. 2025;21:e70332.
    PubMed         Abstract available

  8. VATTATHIL SM, Blostein F, Miller-Fleming TW, Davis LK, et al
    GWAS links APOE to neuropsychiatric symptoms in mild cognitive impairment and dementia.
    Alzheimers Dement. 2025;21:e70329.
    PubMed         Abstract available

  9. HULS A, Liu J, Konwar C, Conneely KN, et al
    Epigenome-wide association study of cerebrospinal fluid-based biomarkers of Alzheimer's disease in cognitively normal individuals.
    Alzheimers Dement. 2025;21:e70318.
    PubMed         Abstract available

  10. VANDERLIP CR, Stark CEL
    Integrating plasma p-tau217 and digital cognitive assessments for early detection in Alzheimer's disease.
    Alzheimers Dement. 2025;21:e70355.
    PubMed         Abstract available

  11. MECCA AP, Ashton NJ, Chen MK, O'Dell RS, et al
    Cerebrospinal fluid and brain positron emission tomography measures of synaptic vesicle glycoprotein 2A: Biomarkers of synaptic density in Alzheimer's disease.
    Alzheimers Dement. 2025;21:e70344.
    PubMed         Abstract available

  12. ROSAS HD, Morgan XC, Tao Y, Lai F, et al
    Gut dysbiosis in Down syndrome: A potentially unexplored culprit for early Alzheimer's disease.
    Alzheimers Dement. 2025;21:e70330.
    PubMed         Abstract available

  13. KUROSE S, Moriguchi S, Kubota M, Tagai K, et al
    Diverse tau pathologies in late-life mood disorders revealed by PET and autopsy assays.
    Alzheimers Dement. 2025;21:e70195.
    PubMed         Abstract available


    Am J Epidemiol

  14. ZIMMERMAN SC, Chen R, Thoma M, Pacca L, et al
    The Association of Alzheimer's Disease Genetic Risk with Social Connectedness in Middle- And Older-Ages.
    Am J Epidemiol. 2025 Jun 11:kwaf122. doi: 10.1093.
    PubMed         Abstract available


    BMC Neurol

  15. SHEIKHI K, Momenabadi V, Khosravi S, Souri A, et al
    Burden of risk factors attributable to Alzheimer's disease and other dementia and its relationship with the Socio-Demographic index in Asia.
    BMC Neurol. 2025;25:247.
    PubMed         Abstract available


    Brain

  16. JIANG S, Srikanth M, Serpe R, Yavari S, et al
    Early proteasome downregulation and dysfunction drive proteostasis failure in Alzheimer's disease.
    Brain. 2025 Jun 9:awaf222. doi: 10.1093.
    PubMed         Abstract available


    Brain Res

  17. SHENG J, Zhu H, Zhou R, Zhang Q, et al
    Bridging the gap between structural and metabolic neuroimaging via MRI-to-PET synthesis: A tri-attention enhanced GAN approach.
    Brain Res. 2025;1862:149691.
    PubMed         Abstract available

  18. KHAN G, Hussain MS, Khan Y, Fatima R, et al
    Ferroptosis and its contribution to cognitive impairment in Alzheimer's disease: mechanisms and therapeutic potential.
    Brain Res. 2025 Jun 9:149776. doi: 10.1016/j.brainres.2025.149776.
    PubMed         Abstract available


    Curr Alzheimer Res

  19. GANDHI P, Panchal S
    Exploring the Neuroprotective Potential of Polyphenolic Compounds in Mitigating Quinolinic Acid-Induced Neurotoxicity in Alzheimer's Disease.
    Curr Alzheimer Res. 2025 Jun 5. doi: 10.2174/0115672050383383250529100802.
    PubMed         Abstract available

  20. KENICHE A, Kalache C, Dib MEA, El Ouar I, et al
    Assessment of the Inhibition of AChE and BChE by Carthamus caeruleus Essential Oil and Carline Oxide: Neuroprotective Effects and In Vivo Toxicity Assessment for the Management of Alzheimer's Disease.
    Curr Alzheimer Res. 2025 Jun 5. doi: 10.2174/0115672050383227250529072253.
    PubMed         Abstract available

  21. KUMAR D, Anand P, Singh S
    Proposed Therapeutic Strategy to Combat Alzheimer's Disease by Targeting Beta and Gamma Secretases.
    Curr Alzheimer Res. 2025 Jun 5. doi: 10.2174/0115672050380899250602042028.
    PubMed         Abstract available

  22. SINGH K, Gupta JK, Lakhchora G, Jain D, et al
    Advance Nanotechnology-Based Drug Delivery Systems for Alzheimer's Disease: Advancements and Future Perspectives.
    Curr Alzheimer Res. 2025 Jun 5. doi: 10.2174/0115672050380959250530112247.
    PubMed         Abstract available


    Dement Geriatr Cogn Disord

  23. SEIDMAN L, Hyman S, Kenney R, Nsiri A, et al
    Tablet-Based Assessment of Picture Naming in Prodromal Alzheimer's Disease: An Accessible and Effective Tool for Distinguishing Mild Cognitive Impairment from Normal Aging.
    Dement Geriatr Cogn Disord. 2025 Jun 11:1-19. doi: 10.1159/000546451.
    PubMed         Abstract available


    J Alzheimers Dis

  24. MARIZZONI M, Coppola L, Festari C, Luongo D, et al
    Circulating short chain fatty acids in Alzheimer's disease: A cross-sectional observational study.
    J Alzheimers Dis. 2025 Jun 12:13872877251337773. doi: 10.1177/13872877251337773.
    PubMed         Abstract available

  25. WANG DW, Qin XT, Wang G, Liu J, et al
    Effect of comprehensive geriatric assessment intervention on serum S100beta levels and clinical outcomes in patients with Alzheimer's disease.
    J Alzheimers Dis. 2025 Jun 10:13872877251344544. doi: 10.1177/13872877251344544.
    PubMed         Abstract available


    J Am Geriatr Soc

  26. O'DONNELL AJ, Fortunato AT, Spitznogle BL, Reddy NM, et al
    Implementation of Lecanemab for Alzheimer's Disease Within the Veterans Health Administration: Facilitators and Barriers.
    J Am Geriatr Soc. 2025 Jun 11. doi: 10.1111/jgs.19577.
    PubMed         Abstract available


    J Clin Psychiatry

  27. LIN YH, Chen MH, Yu SC, Bai YM, et al
    Risk of Alzheimer Disease and Vascular Dementia in Patients With Peripheral Vestibular Disorders: A Longitudinal Study of 140,726 Participants.
    J Clin Psychiatry. 2025;86:24m15699.
    PubMed         Abstract available


    JAMA

  28. RUBIN R
    What to Know About the First FDA-Cleared Blood Test for Alzheimer Biomarkers.
    JAMA. 2025 Jun 13. doi: 10.1001/jama.2025.9013.
    PubMed        


    Nat Neurosci

  29. DA ROCHA JF, Lance ML, Luo R, Schlachter P, et al
    Protective exercise responses in the dentate gyrus of Alzheimer's disease mouse model revealed with single-nucleus RNA-sequencing.
    Nat Neurosci. 2025 Jun 12. doi: 10.1038/s41593-025-01971.
    PubMed         Abstract available


    Nat Rev Neurol

  30. WOOD H
    Alzheimer disease in Down syndrome linked to APOE.
    Nat Rev Neurol. 2025 Jun 9. doi: 10.1038/s41582-025-01110.
    PubMed        


    Neurobiol Aging

  31. SREEPADA LP, Brown CA, Das SR, Yushkevich PA, et al
    Biological age acceleration in Alzheimer's disease modulates relative cortical to medial temporal lobe neurodegeneration.
    Neurobiol Aging. 2025;153:21-29.
    PubMed         Abstract available


    Neurochem Res

  32. AMIN S, Qusti S, Al-Otaibi WA, AlMotwaa SM, et al
    The Neuroprotective Impact of Agomelatine in Preserving Brain Tissue Molecular Structure Against Alzheimer's Disease Etiology.
    Neurochem Res. 2025;50:189.
    PubMed         Abstract available

  33. SHAJI V, Amrutha S, Pervaje R, Abhinand CS, et al
    Exploration of Asparagus racemosus Willd for Alzheimer's Disease Through Integrated Metabolomics and Network Pharmacology Analyses Targeting BACE1 Protein.
    Neurochem Res. 2025;50:190.
    PubMed         Abstract available

  34. JUSTO AFO, Toscano ECB, Goncalves NG, Leite REP, et al
    Selective Vulnerability of Hippocampi for Nitric Oxide Synthases in Alzheimer's Disease Pathology and Cognitive Abilities.
    Neurochem Res. 2025;50:197.
    PubMed         Abstract available


    Neurosci Lett

  35. WANG C, Li J, Liu Q, Yang R, et al
    Expression of concern: "Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-kappaB activation in a rat model of amyloid-beta-induced Alzheimer's disease" [NEUROSCI LETT, Volume 491 (2011) 127-132].
    Neurosci Lett. 2025;859-861:138254.
    PubMed        


    Neuroscience

  36. WANG G, Ma T, Liu R, Gu H, et al
    Comparisons of metabolites and gut microbiota profiles for both young and middle-aged APPSwe/PS1De9 mice.
    Neuroscience. 2025;577:54-63.
    PubMed         Abstract available


    PLoS One

  37. YANG X, Zhou J, Wang C, Li X, et al
    An ensemble-based 3D residual network for the classification of Alzheimer's disease.
    PLoS One. 2025;20:e0324520.
    PubMed         Abstract available

  38. JIN Z, Liu N, Wei H
    Atherosclerosis is associated with amyloid and tau pathology via blood-brain barrier dysfunction in the hippocampus of aged human brains.
    PLoS One. 2025;20:e0324652.
    PubMed         Abstract available


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