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  Alzheimer's Disease

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09.03.2026

4 Alzheimer Dis Assoc Disord
9 Alzheimers Dement
1 Am J Geriatr Psychiatry
1 Am J Pathol
1 Ann Intern Med
1 Brain
1 Brain Res
1 Curr Alzheimer Res
10 J Alzheimers Dis
1 J Biol Chem
1 J Neurol
1 Nat Med
1 Nature
1 Nervenarzt
1 Neurochem Res
1 Neurol Clin Pract
1 Neurology
2 PLoS One
2 Proc Natl Acad Sci U S A
1 Science


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Alzheimer Dis Assoc Disord

  1. DINNERSTEIN E
    Lecanemab and Donanemab Combination Therapy for Alzheimer's Disease-The Cocktail May Work Even Better Together.
    Alzheimer Dis Assoc Disord. 2026;40:65-66.
    PubMed         Abstract available

  2. TOSUN S, Karali FS, Eskioglu EI, Cinar N, et al
    Assessing Language Impairments Across the Neurodegeneration Continuum: Diagnostic Utility of the BECLA-TR in MCI and Alzheimer Disease.
    Alzheimer Dis Assoc Disord. 2026;40:52-58.
    PubMed         Abstract available

  3. AHMED S, Shoaib MH, Farooqi HA, Nadir MA, et al
    Trends and Disparities in Alzheimer Disease-Related Mortality in the United States From 1999 to 2020: A CDC WONDER Analysis.
    Alzheimer Dis Assoc Disord. 2026;40:30-37.
    PubMed         Abstract available

  4. HOU D, Hou Z, Qu H, Sun M, et al
    Serum Expression of miR-106b-3p and Its Diagnostic Significance in Alzheimer Disease.
    Alzheimer Dis Assoc Disord. 2026;40:23-29.
    PubMed         Abstract available


    Alzheimers Dement

  5. YAN J, Zhang J, Ye X, Wang H, et al
    The spleen-brain axis in Alzheimer's disease and related dementias: Integrating immune and metabolic regulation.
    Alzheimers Dement. 2026;22:e71243.
    PubMed         Abstract available

  6. BIBER S, Gothard S, Murchison CF, McLeod L, et al
    A cross-consortium, stakeholder-driven model for implementing a modern electronic data capture and submission system across the Alzheimer's Disease Research Centers Program.
    Alzheimers Dement. 2026;22:e71105.
    PubMed         Abstract available

  7. ATIENZA M, Cantero JL
    In vivo mapping of cortical amyloid beta-myelin coupling in preclinical Alzheimer's disease.
    Alzheimers Dement. 2026;22:e71268.
    PubMed         Abstract available

  8. LEVIN S, Engel B, Carlson C, Hinson J, et al
    An automated plasma-based proteotyping immunoassay for APOE epsilon4 zygosity classification in Alzheimer's disease.
    Alzheimers Dement. 2026;22:e71143.
    PubMed         Abstract available

  9. SAI I, Grill JD, Younes K, Winer JR, et al
    Cognitive screening biases in a secondary prevention Alzheimer's disease clinical trial.
    Alzheimers Dement. 2026;22:e71254.
    PubMed         Abstract available

  10. FOYARD E, Blanchard T, Landeau B, Chauveau L, et al
    Altered locus coeruleus links to atrophy and hypometabolism in individuals with high Alzheimer's disease biomarkers.
    Alzheimers Dement. 2026;22:e71212.
    PubMed         Abstract available

  11. BURNET-MERLIN C, Hay YA, Brecier A
    Implication of the thalamus in sleep alterations observed in Alzheimer's disease.
    Alzheimers Dement. 2026;22:e71242.
    PubMed         Abstract available

  12. LAI Y, Her QL, Zhang Y, Xu H, et al
    The heterogeneous treatment effects of statins on dementia: a target trial emulation with causal machine learning using integrated genetic and real-world data.
    Alzheimers Dement. 2026;22:e71178.
    PubMed         Abstract available

  13. HU WT, Chen MH, Li ML, Su G, et al
    Development and validation of novel cognitive tests in Mandarin-speaking older Americans.
    Alzheimers Dement. 2026;22:e71133.
    PubMed         Abstract available


    Am J Geriatr Psychiatry

  14. GUERRERA CS, Platania GA, Varrasi S, Sarti P, et al
    Investigating the Multidimensional Structure of Apathy in Cognitive Decline: An Exploratory Network Analysis of the Apathy Evaluation Scale.
    Am J Geriatr Psychiatry. 2026;34:450-461.
    PubMed         Abstract available


    Am J Pathol

  15. CASTELLANI RJ, Jamshidi P, Plascencia-Villa G, Perry G, et al
    The Amyloid Cascade Hypothesis: A Conclusion in Search of Support.
    Am J Pathol. 2025;195:1988-1997.
    PubMed         Abstract available


    Ann Intern Med

  16. CENTOR RM, Devi G
    Annals On Call - Alzheimer Disease: A Diagnostic Challenge.
    Ann Intern Med. 2026 Mar 3:e2600835OC. doi: 10.7326/ANNALS-26-00835.
    PubMed        


    Brain

  17. LEE J, Cho Y, Choi BY, Kim HK, et al
    HDAC6 regulates BACE1 stability and NLRP3 inflammasome activation in Alzheimer's disease.
    Brain. 2026 Mar 6:awag089. doi: 10.1093.
    PubMed         Abstract available


    Brain Res

  18. ZHENG M, Su W, Tian L, Gao W, et al
    The glymphatic system as a brain scavenger in Alzheimer's disease: mechanisms and therapeutic implications.
    Brain Res. 2026;1880:150221.
    PubMed         Abstract available


    Curr Alzheimer Res

  19. DAR SA, Imtiaz N, Dar RA
    Early Diagnosis of Alzheimer's: Machine Learning Analysis Leveraging Structural MRI.
    Curr Alzheimer Res. 2026 Feb 26. doi: 10.2174/0115672050421991260125153049.
    PubMed         Abstract available


    J Alzheimers Dis

  20. NOVAK DA, Saleem N, Gerhardt PC, Maestas D, et al
    Alzheimer's disease in patients prescribed statins: A real-world data analysis of U.S. patient health records.
    J Alzheimers Dis. 2026 Feb 27:13872877261424220. doi: 10.1177/13872877261424220.
    PubMed         Abstract available

  21. KIM M, Byun MS, Yi D, Ahn H, et al
    APOE4-dependent association between metformin use and Alzheimer's disease-related cortical thickness in older adults with type 2 diabetes.
    J Alzheimers Dis. 2026 Feb 27:13872877261418688. doi: 10.1177/13872877261418688.
    PubMed         Abstract available

  22. BISSAR N, Kassir R, Missilmani F, Salem-Sokhn E, et al
    Association of post-transcriptional regulatory gene single nucleotide polymorphisms with Alzheimer's disease.
    J Alzheimers Dis. 2026 Feb 27:13872877261424256. doi: 10.1177/13872877261424256.
    PubMed         Abstract available

  23. LIU Y, Zhong R, Li Q, Wang Y, et al
    The role of ionotropic glutamate receptors in Alzheimer's disease: A scientometric analysis.
    J Alzheimers Dis. 2026 Mar 3:13872877261423577. doi: 10.1177/13872877261423577.
    PubMed         Abstract available

  24. YANG Y, Yang F, Yao M, Li L, et al
    Decoding the key mechanisms of ferroptosis and inflammation: Emerging therapeutic targets for Alzheimer's disease.
    J Alzheimers Dis. 2026 Mar 6:13872877261427028. doi: 10.1177/13872877261427028.
    PubMed         Abstract available

  25. DRISCOLL I, Wilson RE, Johnson SC, Asthana S, et al
    Age-related alterations in plasma biomarkers of relevance to Alzheimer's disease are attenuated in KLOTHO KL-VS heterozygotes.
    J Alzheimers Dis. 2026 Mar 6:13872877261422411. doi: 10.1177/13872877261422411.
    PubMed         Abstract available

  26. GIBBS D, Black B, Petersen M, Johnson L, et al
    Exploring feature importance in machine learning for neuroimaging traits in Alzheimer's disease across a multiethnic cohort.
    J Alzheimers Dis. 2026 Mar 6:13872877261426563. doi: 10.1177/13872877261426563.
    PubMed         Abstract available

  27. LI Z, Wang D, Xia F, Liu Y, et al
    Identification of causally linked blood biomarkers for Alzheimer's disease via reverse transcriptome-wide Mendelian randomization.
    J Alzheimers Dis. 2026 Mar 6:13872877261422501. doi: 10.1177/13872877261422501.
    PubMed         Abstract available

  28. BALSLIEMKE AL, Ahlemeyer B, Schmidl E, Acker T, et al
    Region-specific ups and downs in mitochondrial numerical densities during Alzheimer's disease progression: A pilot study in human brains.
    J Alzheimers Dis. 2026 Mar 6:13872877261418994. doi: 10.1177/13872877261418994.
    PubMed         Abstract available

  29. LV M, Wang Q, Yu G, Chen J, et al
    Choroid plexus-glymphatic axis disruption in Alzheimer's disease: Cerebrospinal fluid expansion as a mediator of metabolic dysfunction and cognitive decline.
    J Alzheimers Dis. 2026 Mar 6:13872877261426578. doi: 10.1177/13872877261426578.
    PubMed         Abstract available


    J Biol Chem

  30. FAZELI E, Jan A, Huber AK, Jensen AMG, et al
    A luminescent reporter assay to quantify SORL1 ectodomain shedding and retromer-dependent endosome recycling activity.
    J Biol Chem. 2026;302:111136.
    PubMed         Abstract available


    J Neurol

  31. CHEN Y, Wang Z, Chen H, Cui H, et al
    Plasma p-tau217 assays effectively predict amyloid status but lack precision for tau staging in Alzheimer's disease.
    J Neurol. 2026;273:183.
    PubMed         Abstract available


    Nat Med

  32. MUMMERY CJ, Mayorga AJ, Simmons A, Chow TW, et al
    The TREM2 agonistic antibody AL002 in early Alzheimer's disease: a phase 2 randomized trial.
    Nat Med. 2026 Mar 5. doi: 10.1038/s41591-026-04273.
    PubMed         Abstract available


    Nature

  33. FIELDHOUSE R
    These brain cells clear proteins that contribute to Alzheimer's.
    Nature. 2026 Mar 5. doi: 10.1038/d41586-026-00747.
    PubMed        


    Nervenarzt

  34. SCHONBERGER A, Schild AK, Steinmetz A, Simandi F, et al
    [Optimization of the work of outpatient memory clinics under aspects of value-based healthcare-An approach from the Center for Memory Disorders of the University Hospital Cologne].
    Nervenarzt. 2026;97:163-170.
    PubMed         Abstract available


    Neurochem Res

  35. EL-BAGA SE, Hassan MH, Awadalla EA, Abd El-Kader AEM, et al
    Crocin Mitigates Glutamate Excitotoxicity and Tau Hyperphosphorylation by Modulating EAAT2 and Akt/Tau Pathway in a Scopolamine-induced Rat Model of Alzheimer's Disease.
    Neurochem Res. 2026;51:100.
    PubMed         Abstract available


    Neurol Clin Pract

  36. DEVINSKY O, Leitner DF, Kamondi A, Wisniewski T, et al
    Epilepsy and Alzheimer Disease: Epidemiologic, Clinical, Molecular, and Neuropathologic Convergences and Divergences.
    Neurol Clin Pract. 2026;16:e200589.
    PubMed         Abstract available


    Neurology

  37. ROSS D, Split M, Kunicki Z, Keszycki R, et al
    Neuropsychiatric Symptoms in Patients With Pathologically Confirmed Comorbid Alzheimer Disease and Frontotemporal Lobar Degeneration.
    Neurology. 2026;106:e214750.
    PubMed         Abstract available


    PLoS One

  38. AHMAD I, Waheed S, Alotaibi BS, Abbasi SW, et al
    Cheminformatics-driven discovery of natural isoquinoline alkaloid inhibitors of Beta-secretase I for Alzheimer's management.
    PLoS One. 2026;21:e0343717.
    PubMed         Abstract available

  39. EL FADILI M, Er-Rajy M, Mujwar S, Samadi A, et al
    Computational modeling for rational design of novel phenoxy tacrine derivatives targeting Alzheimer's disease.
    PLoS One. 2026;21:e0343723.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  40. KONSTANTOULEA K, Ramakers M, Borrie SC, T'Syen D, et al
    Phagocytes as plaque catalysts: Human macrophages generate seeding-competent Abeta42 fibrils with cross-seeding activity.
    Proc Natl Acad Sci U S A. 2026;123:e2516774123.
    PubMed         Abstract available

  41. ROH HW, Seo SW, Choi SH, Kim EJ, et al
    Cellular circadian period and its deviation associate with Alzheimer's pathology and brain aging in cognitively impaired older adults.
    Proc Natl Acad Sci U S A. 2026;123:e2527236123.
    PubMed         Abstract available


    Science

  42. BOLES J, Gate D
    Astrocytes engineered to fight Alzheimer's plaques.
    Science. 2026;391:990-991.
    PubMed         Abstract available


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