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21.09.2026

1 Acta Neuropathol
6 Alzheimers Dement
1 Am J Alzheimers Dis Other Demen
3 Ann Neurol
2 Brain Res
1 Exp Neurol
19 J Alzheimers Dis
2 J Am Geriatr Soc
1 J Neurochem
1 J Neurol
1 J Neurol Neurosurg Psychiatry
2 JAMA
1 Nat Med
1 Nat Rev Neurol
3 Nature
1 Proc Natl Acad Sci U S A


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Acta Neuropathol

  1. LAUREYSSEN C, Thal DR, Sleegers K
    A new era of genome-wide association studies in the field of Alzheimer's disease and overlapping co-pathologies: lessons learned from a neuropathology-centered approach.
    Acta Neuropathol. 2026;152:35.
    PubMed         Abstract available


    Alzheimers Dement

  2. PILLAI JA, Alladi S, Appleby BS, Brosch JR, et al
    Operationalizing Alzheimer's disease trials in the era of targeted therapies.
    Alzheimers Dement. 2026;22:e71829.
    PubMed         Abstract available

  3. TEUNISSEN CE, Pini L, Imbimbo BP
    Rethinking tau-targeted therapy in Alzheimer's disease: Toward a dual biomarker strategy.
    Alzheimers Dement. 2026;22:e71867.
    PubMed         Abstract available

  4. PICARD C, Aumont-Rodrigue G, Sarty I, Loncke J, et al
    Genetic and molecular evidence linking CTSH to Alzheimer's disease pathophysiology.
    Alzheimers Dement. 2026;22:e71833.
    PubMed         Abstract available

  5. VANDERLIP CR, Stark CEL
    Digital cognitive phenotyping enhances risk stratification in preclinical Alzheimer's disease.
    Alzheimers Dement. 2026;22:e71834.
    PubMed         Abstract available

  6. DINTICA CS, Bahorik A, Xia F, Boscardin J, et al
    Incidence and risk factors for AD/ADRD among American Indian and Alaska Native US Veterans.
    Alzheimers Dement. 2026;22:e71856.
    PubMed         Abstract available

  7. SHIN J, Muniz-Terrera G, Ritchie CW, Manson J, et al
    Associations between serum estradiol and estrone and Alzheimer's disease biomarkers: An analysis in female participants from the European Prevention of Alzheimer's Dementia Longitudinal Cohort Study (EPAD LCS).
    Alzheimers Dement. 2026;22:e71826.
    PubMed         Abstract available


    Am J Alzheimers Dis Other Demen

  8. LENA O, Todri J
    Global Postural Reeducation in Mild Alzheimer's Disease: A Secondary Analysis of an RCT.
    Am J Alzheimers Dis Other Demen. 2026;41:15333175261489372.
    PubMed         Abstract available


    Ann Neurol

  9. URSO D, Giannelli T, Tafuri B, Giannoni-Luza S, et al
    Alzheimer's Co-Pathology Burden on Basal Forebrain Atrophy and Cognitive Impairment in Dementia with Lewy Bodies: A Cross-Sectional Pilot Study.
    Ann Neurol. 2026 Sep 16. doi: 10.1002/ana.78357.
    PubMed         Abstract available

  10. KOPPISETTI RK, Barthelemy NR, Horie K, Ly CV, et al
    Distribution of Big Tau Isoforms in the Human Central and Peripheral Nervous System.
    Ann Neurol. 2026;100:709-736.
    PubMed         Abstract available

  11. LOW A, Gunter JL, Hu M, Raghavan S, et al
    Perivascular Spaces as Determinants of Amyloid, Tau, and Vascular Biomarker Progression.
    Ann Neurol. 2026;100:695-708.
    PubMed         Abstract available


    Brain Res

  12. JUNWU F, Xiangqian R, Chengyong Y, Dai K, et al
    Alzheimer's disease-associated transcriptional signatures define prognostic subtypes in glioma.
    Brain Res. 2026 Sep 18:150525. doi: 10.1016/j.brainres.2026.150525.
    PubMed         Abstract available

  13. LI Y, Lu C, Liu N, Wang X, et al
    Integrated proteomics and network pharmacology reveal autophagy-lysosomal regulation underlying sulforaphane-mediated neuroprotection in Alzheimer's disease.
    Brain Res. 2026 Sep 14:150549. doi: 10.1016/j.brainres.2026.150549.
    PubMed         Abstract available


    Exp Neurol

  14. GUO F, Li T, He XB
    Dynamic contributions of astrocytes in Alzheimer's disease.
    Exp Neurol. 2026 Sep 17:116032. doi: 10.1016/j.expneurol.2026.116032.
    PubMed         Abstract available


    J Alzheimers Dis

  15. STREIT WJ, Kuhrt H, Bechmann I
    Elevated ferritin expression in microglia and extracellular amyloid-beta deposition are associated with reduced neurofibrillary degeneration in human isocortex, but not allocortex.
    J Alzheimers Dis. 2026;113:734-746.
    PubMed         Abstract available

  16. SHIN SH, Mo Y, Hwang HS, Lee M, et al
    MRI-free amyloid PET quantification using a deep learning model and white matter reference.
    J Alzheimers Dis. 2026;113:650-660.
    PubMed         Abstract available

  17. COSTA T, Sensi SL, Hoilund-Carlsen PF, Robakis NK, et al
    Do anti-amyloid therapies demonstrate clinically meaningful benefit? A Bayesian reappraisal.
    J Alzheimers Dis. 2026;113:593-597.
    PubMed         Abstract available

  18. BEKENA S, Singh RK, Pal S, Zhu Y, et al
    Hearing in noise and cognitive status in older adults: Biomarker associations and bidirectional survival analyses.
    J Alzheimers Dis. 2026;113:769-780.
    PubMed         Abstract available

  19. HADJI M, Moradi E, Tohka J
    Predicting future brain atrophy based on longitudinal MRI.
    J Alzheimers Dis. 2026;113:796-812.
    PubMed         Abstract available

  20. NOVOTNY JS, Thatcher A, Shatti D, Mofardin S, et al
    Evaluation of the Addenbrooke's Cognitive Examination-Revised in a routine cognitive outpatient clinic.
    J Alzheimers Dis. 2026;113:822-834.
    PubMed         Abstract available

  21. VAN HOUWELINGEN AS, Vernooij MW, Vermeiren MR, Ossenkoppele R, et al
    Concordance between plasma biomarkers of phosphorylated tau and tau-PET: A narrative review.
    J Alzheimers Dis. 2026;113:561-577.
    PubMed         Abstract available

  22. KOIZUMI Y, Nakano Y, Tamura M, Yamagishi K, et al
    Cerebral perfusion correlates of domain-specific cognitive function in Alzheimer's disease and dementia with Lewy bodies.
    J Alzheimers Dis. 2026 Sep 14:13872877261482134. doi: 10.1177/13872877261482134.
    PubMed         Abstract available

  23. XU Z, Bao L, Zhou S, Xue C, et al
    Altered neurovascular coupling in mild cognitive impairment and Alzheimer's disease: Associations with polysomnography-derived sleep parameters and cognition.
    J Alzheimers Dis. 2026 Sep 15:13872877261487585. doi: 10.1177/13872877261487585.
    PubMed         Abstract available

  24. SU Z, Liu M, Su L, Kuai J, et al
    Associations of plasma lipid burden with cognitive performance and decline across dementia with Lewy bodies, Alzheimer's disease, and Parkinson's disease dementia.
    J Alzheimers Dis. 2026 Sep 15:13872877261487127. doi: 10.1177/13872877261487127.
    PubMed         Abstract available

  25. WANG M, Jing C, Wu T, Wang D, et al
    A parsimonious three-gene mitochondrial classifier from frontal cortex for Alzheimer's disease: Nested cross-validation and multicenter external validation.
    J Alzheimers Dis. 2026 Sep 15:13872877261487424. doi: 10.1177/13872877261487424.
    PubMed         Abstract available

  26. SANCHEZ-SOBLECHERO A, Villarejo A, Carreras MT, Berbel A, et al
    Validation of plasma core biomarkers of Alzheimer's disease: A multicenter study in usual practice conditions.
    J Alzheimers Dis. 2026 Sep 16:13872877261487171. doi: 10.1177/13872877261487171.
    PubMed         Abstract available

  27. ALCAIDE-PRADOS MDC, Gomez-Moreno G, Leizaola-Cardesa IO, Moreu G, et al
    Periodontal disease and Alzheimer's disease: A systematic review.
    J Alzheimers Dis. 2026 Sep 17:13872877261488806. doi: 10.1177/13872877261488806.
    PubMed         Abstract available

  28. WISEMAN FK
    New mouse models for Down syndrome Alzheimer's disease.
    J Alzheimers Dis. 2026 Sep 17:13872877261488873. doi: 10.1177/13872877261488873.
    PubMed         Abstract available

  29. CASTELLANI RJ
    Traumatic brain injury and Alzheimer's disease: The null hypothesis wins.
    J Alzheimers Dis. 2026 Sep 17:13872877261489299. doi: 10.1177/13872877261489299.
    PubMed         Abstract available

  30. XU L, Wei N, Ran Y
    The dynamic connectome in Alzheimer's disease: From static snapshots to a symphony in time-A hypothesis.
    J Alzheimers Dis. 2026 Sep 18:13872877261488872. doi: 10.1177/13872877261488872.
    PubMed         Abstract available

  31. CHOI JJ, Engelman CD, Lu T
    Multi-omics integration of transcriptomics and metabolomics with machine learning uncovers novel risk factors for Alzheimer's disease.
    J Alzheimers Dis. 2026 Sep 18:13872877261487621. doi: 10.1177/13872877261487621.
    PubMed         Abstract available

  32. RAMEZANNEZHAD E, Dehghani M
    Utility of biomarkers in prediction of future cognition in Alzheimer's disease continuum changes over time.
    J Alzheimers Dis. 2026 Sep 18:13872877261487572. doi: 10.1177/13872877261487572.
    PubMed         Abstract available

  33. LI R, Zhang B, Qiao Y, Zhu L, et al
    Association between caregiving status and cognitive function as well as activities of daily living among community-dwelling older adults with Alzheimer's disease: A cross-sectional study.
    J Alzheimers Dis. 2026 Sep 18:13872877261488017. doi: 10.1177/13872877261488017.
    PubMed         Abstract available


    J Am Geriatr Soc

  34. JANG S, Chen J
    Hospital Artificial Intelligence Tools and Inpatient Utilization and Costs in Older Adults with Alzheimer's Disease and Related Dementias.
    J Am Geriatr Soc. 2026 Sep 14. doi: 10.1111/jgs.70704.
    PubMed         Abstract available

  35. SUJANA RS, McCaffery KJ, Nickel B, Fox R, et al
    Social Media Claims About Blood Tests for Alzheimer's Disease and Dementia: A Cross-Sectional Content Analysis.
    J Am Geriatr Soc. 2026 Sep 15. doi: 10.1111/jgs.70692.
    PubMed        


    J Neurochem

  36. PASSARELLA D, Russo C
    Rethinking gamma-Secretase Dysfunction in Alzheimer's Disease: From APP Processing to Network Perturbation.
    J Neurochem. 2026;170:e70550.
    PubMed        


    J Neurol

  37. CHEN T, Sun Q, Foxe D, Narasimhan M, et al
    Behavioural and psychological symptom determinants of carer burden across clinical syndromes associated with frontotemporal lobar degeneration and Alzheimer's disease: a transdiagnostic analysis.
    J Neurol. 2026;273:592.
    PubMed         Abstract available


    J Neurol Neurosurg Psychiatry

  38. JIMENEZ-HUETE A, Rognoni T, Montoya G, Borda MG, et al
    Diagnostic accuracy of a two-cut-off approach using the FAQ/MMSE ratio and FAQ for clinical preselection of patients for anti-amyloid therapy.
    J Neurol Neurosurg Psychiatry. 2026;97:869-872.
    PubMed         Abstract available


    JAMA

  39. ANDERER S
    FDA Approves 2 New Alzheimer Disease Blood Tests.
    JAMA. 2026 Sep 18. doi: 10.1001/jama.2026.14721.
    PubMed        

  40. BUCKLEY RF, Townsend DL, Birkenbihl CJ, Cuppels M, et al
    Prognostic Value of Blood-Based P-Tau217 Levels for Progression to Cognitive Impairment.
    JAMA. 2026;336:950-959.
    PubMed         Abstract available


    Nat Med

  41. ABILA E, Buljan I, Zheng Y, Kleissl L, et al
    Histological aging signatures for monitoring tissue-specific aging and disease.
    Nat Med. 2026;32:3466-3476.
    PubMed         Abstract available


    Nat Rev Neurol

  42. GRINBERG LT, Murray ME
    Atypical Alzheimer disease: a multi-axis framework toward defining heterogeneity.
    Nat Rev Neurol. 2026 Sep 18. doi: 10.1038/s41582-026-01267.
    PubMed         Abstract available


    Nature

  43. DE STROOPER B, Karran E
    Inflection points and transitions in Alzheimer's disease.
    Nature. 2026 Sep 16. doi: 10.1038/s41586-026-11110.
    PubMed         Abstract available

  44. NADDAF M
    Map of brain 'microproteins' could offer new clues to Alzheimer's disease.
    Nature. 2026 Sep 16. doi: 10.1038/d41586-026-02914.
    PubMed        


  45. Cognitive resilience helps to predict Alzheimer's dementia.
    Nature. 2026 Sep 18. doi: 10.1038/d41586-026-02897.
    PubMed        


    Proc Natl Acad Sci U S A

  46. LIU X, Gu J, Chen Z, Chu B, et al
    Uncovering heterogeneous effects via localized feature selection.
    Proc Natl Acad Sci U S A. 2026;123:e2527033123.
    PubMed         Abstract available


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