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Alzheimer's Disease

Free Subscription 03.11.2025 2 Acta Neuropathol 19 Alzheimers Dement 1 Am J Geriatr Psychiatry 1 Biochemistry 1 BMC Geriatr 1 Brain 1 Brain Res 5 Curr Alzheimer Res 2 Exp Neurol 2 Geriatrics (Basel) 18 J Alzheimers Dis 2 J Am Geriatr Soc 1 J Biol Chem 1 J Neural Transm (Vienna) 1 J Neurosci 1 Neurobiol Dis 1 Neurology 2 PLoS One 3 Proc Natl Acad Sci U S A 2 Science

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Single Articles

Acta Neuropathol

1. ZHANG Z, Capuano AW, Beadell A, Tasaki S, et al
   Brain-derived 5-hydroxymethylcytosine epigenetic scores are related to Alzheimer's disease pathology and cognitive decline.
   Acta Neuropathol. 2025;150:45.
   PubMed         Abstract available
   
   
2. NEUBAUER A, Weissenbrunner D, Pekrun S, Roeber S, et al
   Alpha-synuclein deposition patterns in Alzheimer's disease: association with cortical amyloid beta and variable tau load.
   Acta Neuropathol. 2025;150:46.
   PubMed         Abstract available
   
   

   
   Alzheimers Dement

3. VAN GILS V, Jansen WJ, van der Flier WM, Martinez-Lage P, et al
   The association of diabetes with Alzheimer's disease biomarkers and vascular burden across European aging and memory clinic cohorts.
   Alzheimers Dement. 2025;21:e70804.
   PubMed         Abstract available
   
   
4. ANDRE C, Stankeviciute L, Michaelian JC, Antonsdottir IM, et al
   International recommendations for sleep and circadian research in aging and Alzheimer's disease: A Delphi consensus study.
   Alzheimers Dement. 2025;21:e70742.
   PubMed         Abstract available
   
   
5. LIU S, Huang YN, Park T, Lee EH, et al
   Plasma proteomic Alzheimer's risk score: Biological age clock and pseudotime trajectory.
   Alzheimers Dement. 2025;21:e70851.
   PubMed         Abstract available
   
   
6. UZUN C, Li Y, Liu S
   APOE epsilon4 disrupts neuronal and network-level function in the anterior olfactory nucleus: Influence of age and sex.
   Alzheimers Dement. 2025;21:e70865.
   PubMed         Abstract available
   
   
7. KANG KM, Park C, Byun MS, Yi D, et al
   APOE4 modulates the association between DTI-ALPS index and Alzheimer's pathologies.
   Alzheimers Dement. 2025;21:e70837.
   PubMed         Abstract available
   
   
8. DING J, Zhao C, Hao X, Jiao H, et al
   Glymphatic and meningeal lymphatic dysfunction in Alzheimer's disease: Mechanisms and therapeutic perspectives.
   Alzheimers Dement. 2025;21:e70709.
   PubMed         Abstract available
   
   
9. KIM H, Jutten RJ, Soberanes D, Dubbelman MA, et al
   Using memory recall response time on digital cognitive testing to detect subtle cognitive changes among cognitively unimpaired older adults.
   Alzheimers Dement. 2025;21:e70815.
   PubMed         Abstract available
   
   
10. THOMAS AB, Matthews AL, Brooks O, Winquist A, et al
    Psychometric properties of the NIH Toolbox Cognition Battery composites in older adults at risk for Alzheimer's disease and related dementias: A systematic review.
    Alzheimers Dement. 2025;21:e70673.
    PubMed         Abstract available
    
    
11. LANSKEY JH, Jafarian A, Karadag M, Kocagoncu E, et al
    Alzheimer's disease and its progression reduce pyramidal cell gain and connectivity.
    Alzheimers Dement. 2025;21:e70805.
    PubMed         Abstract available
    
    
12. SACHS BC, Latham LA, Isom S, Clark LR, et al
    Multi-site video-based assessment with the NACC UDS-Version 3 battery: Design and participant experience in the V-Cog study.
    Alzheimers Dement. 2025;21:e70842.
    PubMed         Abstract available
    
    
13. SOREQ E, Kolanko MA, Ravindran KKG, Della Monica C, et al
    Contactless longitudinal monitoring in the home characterizes aging and Alzheimer's disease-related night-time behavior and physiology.
    Alzheimers Dement. 2025;21:e70758.
    PubMed         Abstract available
    
    
14. DEVANARAYAN V, Horie K, Wildsmith K, Doherty T, et al
    Combining CSF MTBR-tau243 and plasma pTau217 ratio enhances the prediction of continuous regional tau PET burden in early Alzheimer's disease.
    Alzheimers Dement. 2025;21:e70881.
    PubMed         Abstract available
    
    
15. DELABY C, Gabelle A, Duchiron M, Busto G, et al
    Impact of preanalytical delay on the performance of plasma Abeta42, Abeta42/40, p-tau217, and p-tau217/Abeta42 in detecting brain amyloidosis in the ALZAN cohort.
    Alzheimers Dement. 2025;21:e70867.
    PubMed         Abstract available
    
    
16. BHEMBRE N, Boskovic Z, Willshaw JL, Castello-Waldow T, et al
    Direct evidence for dendritic spine compensation and regeneration in Alzheimer's disease models.
    Alzheimers Dement. 2025;21:e70829.
    PubMed         Abstract available
    
    
17. EIJANSANTOS E, Allen IE, de Leon J, Grasso S, et al
    Burden of psychiatric disease inversely correlates with Alzheimer's age at onset.
    Alzheimers Dement. 2025;21:e70677.
    PubMed         Abstract available
    
    
18. DOECKE JD, Stage E, Fowler C, Dore V, et al
    Multivariate models using NULISAseq and plasma p-tau217 for staging Alzheimer's disease.
    Alzheimers Dement. 2025;21:e70793.
    PubMed         Abstract available
    
    
19. 
    Correction to "Identification of 16 novel Alzheimer's disease loci using multi-ancestry meta-analyses".
    Alzheimers Dement. 2025;21:e70854.
    PubMed        
    
    
20. CHAN D, de Weck G, Jackson BL, Suk HJ, et al
    Gamma sensory stimulation in mild Alzheimer's dementia: An open-label extension study.
    Alzheimers Dement. 2025;21:e70792.
    PubMed         Abstract available
    
    
21. WISCH JK, McKay NS, Zammit M, Christian BT, et al
    Comparison of amyloid chronicity and EYO in autosomal dominant Alzheimer's disease.
    Alzheimers Dement. 2025;21:e70812.
    PubMed         Abstract available
    
    

    
    Am J Geriatr Psychiatry

22. JENKINS LM, Heywood AA, Gurvich C
    Beyond Alzheimer's Pathology: Contributions to Cognitive Decline in Late Life Depression.
    Am J Geriatr Psychiatry. 2025 Sep 30:S1064-7481(25)00489.
    PubMed        
    
    

    
    Biochemistry

23. HERNANDEZ ARRIAZA R, Reil D, Fatuzzo N, Fu M, et al
    ApoE is Secreted as a Lipid Nanoparticle by Mammalian Cells: Implications for Alzheimer's Disease Pathogenesis.
    Biochemistry. 2025 Oct 24. doi: 10.1021/acs.biochem.5c00503.
    PubMed         Abstract available
    
    

    
    BMC Geriatr

24. KATAGIRI R, Yamada Y, Shinkawa K, Kobayashi M, et al
    Dual-task walking for early detection of Alzheimer's disease: comparative analysis of tasks using whole-body gait variables.
    BMC Geriatr. 2025;25:807.
    PubMed         Abstract available
    
    

    
    Brain

25. NEITZEL J
    White matter changes in Alzheimer's disease: contributor, consequence or co-pathology?
    Brain. 2025 Oct 30:awaf415. doi: 10.1093.
    PubMed        
    
    

    
    Brain Res

26. LIU Z, Kuang L, Zhou X, Zhao J, et al
    Effect of the plasma lipidome, immune cells, inflammatory proteins, gut microbiota, and plasma metabolites on Alzheimer's Disease: A two-sample Mendelian randomized study and mediation analysis.
    Brain Res. 2025;1869:150009.
    PubMed         Abstract available
    
    

    
    Curr Alzheimer Res

27. BEHROUZINIA S, Afshar M, Khanteymoori A
    Spectral Biomarkers of Functional Brain Network Alteration in Alzheimer's Disease.
    Curr Alzheimer Res. 2025 Oct 24. doi: 10.2174/0115672050434251251008104505.
    PubMed         Abstract available
    
    
28. SHI Y, Luo W, Hu Y, Chen W, et al
    Low-Dimensional Nanomaterials in Alzheimer's Disease: Current Applications.
    Curr Alzheimer Res. 2025 Oct 24. doi: 10.2174/0115672050413838251014045255.
    PubMed         Abstract available
    
    
29. ZHAO R, Che M, Cui Y, Peng J, et al
    The Role of Lipoprotein and Gut Microbiome in Alzheimer's Disease: A Review of Novel Findings and Potential Applications.
    Curr Alzheimer Res. 2025 Oct 24. doi: 10.2174/0115672050407276251014113234.
    PubMed         Abstract available
    
    
30. SINGH B, Singh K, Gupta JK, Semwal BC, et al
    Innovative Approaches in Molecular Docking for the Discovery of Novel Inhibitors Against Alzheimer's Disease.
    Curr Alzheimer Res. 2025 Oct 22. doi: 10.2174/0115672050386924250930184405.
    PubMed         Abstract available
    
    
31. YAO L, Ni J, Wei M, Li T, et al
    Recent Advances in the Application of Artificial Intelligence in Alzheimer's Disease.
    Curr Alzheimer Res. 2025 Oct 22. doi: 10.2174/0115672050410489250930175402.
    PubMed         Abstract available
    
    

    
    Exp Neurol

32. YOUSEFI A, Karimani F, Delphi L, Ghahfarokhi MR, et al
    Modulation of the mediodorsal thalamus nitric oxide system ameliorated amnesia and medial prefrontal abnormal network activity in a streptozotocin-induced rat model of Alzheimer's disease.
    Exp Neurol. 2025 Oct 22:115524. doi: 10.1016/j.expneurol.2025.115524.
    PubMed         Abstract available
    
    
33. ZHENG M, Zhang Q, Siebert HC, Loers G, et al
    Semaglutide attenuates Alzheimer's disease model progression by targeting microglial NLRP3 inflammasome-mediated neuroinflammation and ferroptosis.
    Exp Neurol. 2025 Oct 29:115537. doi: 10.1016/j.expneurol.2025.115537.
    PubMed         Abstract available
    
    

    
    Geriatrics (Basel)

34. ADELEKE T, Knelsen-Dobson A, McGinity S, Fontaine KM, et al
    Alzheimer's Disease in Illinois: Analyzing Disparities and Projected Trends.
    Geriatrics (Basel). 2025;10:132.
    PubMed         Abstract available
    
    
35. CERMELLI A, Crisafi A, Chiarandon AM, Mirabelli G, et al
    Exploring Frailty Status and Blood Biomarkers: A Multidimensional Approach to Alzheimer's Diagnosis.
    Geriatrics (Basel). 2025;10:133.
    PubMed         Abstract available
    
    

    
    J Alzheimers Dis

36. XUE D, Blue EE, Wood AC, Rotter JI, et al
    Risk score roulette: A cautionary tale of polygenic risk score reliability.
    J Alzheimers Dis. 2025;108:65-70.
    PubMed         Abstract available
    
    
37. ABBATE C, Gallucci A
    The study of plaques and tangles makes few and inaccurate predictions about the main features of cognitive disorders: A narrative review.
    J Alzheimers Dis. 2025;108:5-18.
    PubMed         Abstract available
    
    
38. GU H, Yu K, Zhou J, Chu B, et al
    Perturbations in lipid metabolism mediate the relationship between cholecystectomy and dementia: A mediation Mendelian randomization study.
    J Alzheimers Dis. 2025;108:324-333.
    PubMed         Abstract available
    
    
39. MICHELUTTI M, Cenacchi V, Lombardo T, Palacino F, et al
    Regional gyrification alterations and metabolic correlates in biologically defined Alzheimer's disease using a multimodal approach.
    J Alzheimers Dis. 2025 Oct 29:13872877251390876. doi: 10.1177/13872877251390876.
    PubMed         Abstract available
    
    
40. BANERJEE A, Yang F, Dutta J, Cacciola A, et al
    Atrophy patterns of deep gray matter nuclei in Alzheimer's disease and frontotemporal dementia.
    J Alzheimers Dis. 2025 Oct 29:13872877251390386. doi: 10.1177/13872877251390386.
    PubMed         Abstract available
    
    
41. KIM M, Kwon H, Sohn S, Lee WJ, et al
    Alzheimer's disease diagnosis and treatment: From pathophysiological insights to therapeutic advances in the era of precision neurology (2025 review).
    J Alzheimers Dis. 2025 Oct 29:13872877251391820. doi: 10.1177/13872877251391820.
    PubMed         Abstract available
    
    
42. SINGH S, Kumar U
    Brain region-specific dopamine receptor changes and astrocyte activation influence tau pathology through CDK5 in Alzheimer's disease models.
    J Alzheimers Dis. 2025 Oct 29:13872877251389961. doi: 10.1177/13872877251389961.
    PubMed         Abstract available
    
    
43. CURY RM, da Silva T, Cezar-Dos-Santos F, Fakih YRC, et al
    A randomized clinical trial of low-dose cannabis extract in Alzheimer's disease.
    J Alzheimers Dis. 2025 Oct 29:13872877251389608. doi: 10.1177/13872877251389608.
    PubMed         Abstract available
    
    
44. JIAO Y, Ding Y, Luo N, Niu M, et al
    MicroRNA biomarkers in cerebrospinal fluid and plasma predicting cognitive decline in Alzheimer's disease.
    J Alzheimers Dis. 2025 Oct 29:13872877251390836. doi: 10.1177/13872877251390836.
    PubMed         Abstract available
    
    
45. CHOI YJ, Oh DJ, Han JW, Kim KW, et al
    Development and validation of a weighted Subjective Memory Complaints Questionnaire (SMCQ-R) for early symptomatic Alzheimer's disease detection.
    J Alzheimers Dis. 2025 Oct 28:13872877251390383. doi: 10.1177/13872877251390383.
    PubMed         Abstract available
    
    
46. SONG W, Gong C, Li Y, Yang D, et al
    Alzheimer's disease pathogenesis and the role of APOE epsilon4 in remodeling functional gradients of the default mode network.
    J Alzheimers Dis. 2025 Oct 27:13872877251389965. doi: 10.1177/13872877251389965.
    PubMed         Abstract available
    
    
47. YANG H, You X, Yue C, Yu X, et al
    Uncovering the cytophenotypic and transcriptomic features of natural killer cells derived from peripheral blood of patients with Alzheimer's disease.
    J Alzheimers Dis. 2025 Oct 27:13872877251390553. doi: 10.1177/13872877251390553.
    PubMed         Abstract available
    
    
48. KHALSA DS, Lavretsky H, Reddy MY, Fenn A, et al
    Air pollution and Alzheimer's disease prevention: The science and a prevention plan.
    J Alzheimers Dis. 2025 Oct 24:13872877251386482. doi: 10.1177/13872877251386482.
    PubMed         Abstract available
    
    
49. KETATA I, Ellouz E
    Artificial intelligence-driven eye tracker models for Alzheimer's disease diagnosis: A systematic review and meta-analysis.
    J Alzheimers Dis. 2025 Oct 24:13872877251389145. doi: 10.1177/13872877251389145.
    PubMed         Abstract available
    
    
50. MULLINS CA, Gannaban RB, Kramer A, Shah H, et al
    Early branched-chain amino acid reduction delays the onset of cognitive decline in a mouse model of Alzheimer's disease.
    J Alzheimers Dis. 2025 Oct 24:13872877251389236. doi: 10.1177/13872877251389236.
    PubMed         Abstract available
    
    
51. JIN H, He J, Zhang W, Wang Y, et al
    The association between Alzheimer-associated neuronal thread protein (AD7c-NTP) and plasma inflammatory cytokine levels in individuals with cognitive impairment and demographically-matched controls.
    J Alzheimers Dis. 2025 Oct 24:13872877251389239. doi: 10.1177/13872877251389239.
    PubMed         Abstract available
    
    
52. ZHANG Y, Dong X, Yang Y, Wang X, et al
    Caregiving burden, disease-related knowledge, and quality of life among primary caregivers in Alzheimer's disease: A cross-sectional study.
    J Alzheimers Dis. 2025 Oct 24:13872877251390494. doi: 10.1177/13872877251390494.
    PubMed         Abstract available
    
    
53. SAAK TM, Tervo JP, Motter JN, Overdevest JB, et al
    Expanding the scope of olfactory evaluation in Alzheimer's disease and related dementias (ADRD): A narrative review of the role for odor memory and recognition in AD/ADRD.
    J Alzheimers Dis. 2025 Oct 27:13872877251389113. doi: 10.1177/13872877251389113.
    PubMed         Abstract available
    
    

    
    J Am Geriatr Soc

54. LI X, Singh S, DeVries A, Gurwitz JH, et al
    Lecanemab Therapy Use Patterns for Alzheimer's Disease Among Early Initiators in a Large National Health Plan.
    J Am Geriatr Soc. 2025;73:3203-3207.
    PubMed         Abstract available
    
    
55. SOCAL MP, Markell J, Bareamichael PI, Bai G, et al
    Mail-Order and Retail Pharmacy Use Among Medicare Beneficiaries With Alzheimer's Disease and Related Dementias.
    J Am Geriatr Soc. 2025 Oct 31. doi: 10.1111/jgs.70188.
    PubMed        
    
    

    
    J Biol Chem

56. AMBAREEN N, Gharami K, Mondal A, Sarkar UA, et al
    Sertad1 is elevated and plays a necessary role in neuron loss and cognitive impairment in a mouse model of Alzheimer's disease.
    J Biol Chem. 2025 Oct 29:110875. doi: 10.1016/j.jbc.2025.110875.
    PubMed         Abstract available
    
    

    
    J Neural Transm (Vienna)

57. CHAMORRO LB, Zulli B, Barone E
    Insulin resistance: fueling oxidative stress and neurodegeneration.
    J Neural Transm (Vienna). 2025;132:1567-1586.
    PubMed         Abstract available
    
    

    
    J Neurosci

58. FU CH, Park J, Tosi U, Blanco FA, et al
    Restoration of sFRP3 preserves the neural stem cell pool and spatial discrimination ability in a mouse model of Alzheimer's disease.
    J Neurosci. 2025 Oct 24:e0049252025. doi: 10.1523/JNEUROSCI.0049-25.2025.
    PubMed         Abstract available
    
    

    
    Neurobiol Dis

59. WEI J, Xiao T, Lyu J, Zhao Y, et al
    Mitophagy in Alzheimer's disease and its potential as a therapeutic target.
    Neurobiol Dis. 2025 Oct 28:107162. doi: 10.1016/j.nbd.2025.107162.
    PubMed         Abstract available
    
    

    
    Neurology

60. BENITO-LEON J, Benito-Rodriguez CM
    Essential Tremor Dementia: Alzheimer Disease in Disguise?
    Neurology. 2025;105:e214420.
    PubMed        
    
    

    
    PLoS One

61. RONCERO C, Popov A, Seixas-Lima B, Lahiri D, et al
    Baseline task performance predicts mini-mental state examination improvement after individuals with dementia practice an N-back task with bilateral transcranial direct current stimulation.
    PLoS One. 2025;20:e0332372.
    PubMed         Abstract available
    
    
62. KOJIMA N, Osuka Y, Sasai H, Shinkai S, et al
    Lower Firmicutes abundance in gut microbiota associated with amyloid-beta positivity in older adults in Japan as assessed by positron emission tomography.
    PLoS One. 2025;20:e0332801.
    PubMed         Abstract available
    
    

    
    Proc Natl Acad Sci U S A

63. WEARN A, Tardif CL, Leppert IR, Baracchini G, et al
    Quantitative MRI of the hippocampus reveals microstructural trajectories of aging and Alzheimer's disease pathology.
    Proc Natl Acad Sci U S A. 2025;122:e2502674122.
    PubMed         Abstract available
    
    
64. ARAGONES PEDROLA J, Dekker FA, Garfagnini T, Mayer G, et al
    FibrilPaint to determine the length of Tau amyloids in fluids.
    Proc Natl Acad Sci U S A. 2025;122:e2502847122.
    PubMed         Abstract available
    
    
65. ULKU I, Ansari FE, Hancock MA, Zhou H, et al
    Characterization of endothelin-converting enzyme 1 as a key enzyme in the multienzyme Abeta degradation pathway.
    Proc Natl Acad Sci U S A. 2025;122:e2507450122.
    PubMed         Abstract available
    
    

    
    Science

66. DEPP C
    White matters arising: Rethinking Alzheimer's disease through the lens of myelin.
    Science. 2025;390:483.
    PubMed         Abstract available
    
    
67. DONG G, Ma CC, Mao S, Brown KS, et al
    Diverse somatic genomic alterations in single neurons in chronic traumatic encephalopathy.
    Science. 2025;390:eadu1351.
    PubMed         Abstract available
    
    

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