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  Alzheimer's Disease

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26.04.2021

1 Acta Neuropathol
3 Alzheimers Dement
4 Biol Psychiatry
1 BMC Geriatr
1 BMC Neurol
6 Brain
2 Curr Alzheimer Res
1 Exp Neurol
13 J Alzheimers Dis
1 J Am Geriatr Soc
1 J Neurosci
1 MMWR Morb Mortal Wkly Rep
2 Neurochem Res
1 Neurology
1 Neurosci Lett
1 Neuroscience
2 PLoS Genet
1 Proc Natl Acad Sci U S A


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Acta Neuropathol

  1. VALVERDE A, Dunys J, Lorivel T, Debayle D, et al
    Aminopeptidase A contributes to biochemical, anatomical and cognitive defects in Alzheimer's disease (AD) mouse model and is increased at early stage in sporadic AD brain.
    Acta Neuropathol. 2021 Apr 21. pii: 10.1007/s00401-021-02308.
    PubMed         Abstract available


    Alzheimers Dement

  2. RANASINGHE KG, Petersen C, Kudo K, Mizuiri D, et al
    Reduced synchrony in alpha oscillations during life predicts post mortem neurofibrillary tangle density in early-onset and atypical Alzheimer's disease.
    Alzheimers Dement. 2021 Apr 21. doi: 10.1002/alz.12349.
    PubMed         Abstract available

  3. LI X, Tsolis KC, Koper MJ, Ronisz A, et al
    Sequence of proteome profiles in preclinical and symptomatic Alzheimer's disease.
    Alzheimers Dement. 2021 Apr 19. doi: 10.1002/alz.12345.
    PubMed         Abstract available

  4. SABBAGH MN, Cummings J
    Open Peer Commentary to "Failure to demonstrate efficacy of aducanumab: An analysis of the EMERGE and ENGAGE Trials as reported by Biogen December 2019".
    Alzheimers Dement. 2021;17:702-703.
    PubMed        


    Biol Psychiatry

  5. XU W, Feng W, Shen XN, Bi YL, et al
    Amyloid Pathologies Modulate the Associations of Minimal Depressive Symptoms With Cognitive Impairments in Older Adults Without Dementia.
    Biol Psychiatry. 2021;89:766-775.
    PubMed         Abstract available

  6. MACKIN RS, Insel PS
    Reply to: Brain Amyloid Deposition in Late-Life Depression.
    Biol Psychiatry. 2020 Nov 11. pii: S0006-3223(20)31949.
    PubMed        

  7. POMARA N, Imbimbo BP
    Brain Amyloid Deposition in Late-Life Depression.
    Biol Psychiatry. 2020 Nov 11. pii: S0006-3223(20)31948.
    PubMed        

  8. VAN DYCK CH, O'Dell RS, Mecca AP
    Amyloid-Associated Depression-or Not?
    Biol Psychiatry. 2021;89:737-738.
    PubMed        


    BMC Geriatr

  9. LU Y, Liu C, Yu D, Fawkes S, et al
    Prevalence of mild cognitive impairment in community-dwelling Chinese populations aged over 55 years: a meta-analysis and systematic review.
    BMC Geriatr. 2021;21:10.
    PubMed         Abstract available


    BMC Neurol

  10. QIAN S, Chen K, Guan Q, Guo Q, et al
    Performance of Mattis dementia rating scale-Chinese version in patients with mild cognitive impairment and Alzheimer's disease.
    BMC Neurol. 2021;21:172.
    PubMed         Abstract available


    Brain

  11. DEHGHANI N, Bras J, Guerreiro R
    How understudied populations have contributed to our understanding of Alzheimer's disease genetics.
    Brain. 2021 Apr 23. pii: 6247156. doi: 10.1093.
    PubMed         Abstract available

  12. O'CONNOR A, Pannee J, Poole T, Arber C, et al
    Plasma amyloid-beta ratios in autosomal dominant Alzheimer's disease: the influence of genotype.
    Brain. 2021 Apr 23. pii: 6248083. doi: 10.1093.
    PubMed         Abstract available


  13. Erratum to: Time course of phosphorylated-tau181 in blood across the Alzheimer's disease spectrum.
    Brain. 2021 Apr 20. pii: 6238673. doi: 10.1093.
    PubMed        

  14. KIM JH, Afridi R, Han J, Jung HG, et al
    Gamma subunit of complement component 8 is a neuroinflammation inhibitor.
    Brain. 2021;144:528-552.
    PubMed         Abstract available

  15. JOHNSON JCS, Marshall CR, Weil RS, Bamiou DE, et al
    Hearing and dementia: from ears to brain.
    Brain. 2020 Dec 22. pii: 6044086. doi: 10.1093.
    PubMed         Abstract available

  16. YAO Y, Kang SS, Xia Y, Wang ZH, et al
    A delta-secretase-truncated APP fragment activates CEBPB, mediating Alzheimer's disease pathologies.
    Brain. 2021 Apr 20. pii: 6242262. doi: 10.1093.
    PubMed         Abstract available


    Curr Alzheimer Res

  17. GALLINI A, Jegou D, Lapeyre-Mestre M, Couret A, et al
    Development and Validation of a Model to Identify Alzheimer's Disease and Related Syndromes in Administrative Data.
    Curr Alzheimer Res. 2021 Apr 15. pii: CAR-EPUB-115358.
    PubMed         Abstract available

  18. PATHAK GA, Barbe RC, Phillips NR
    Multiomics Investigation of Hypertension and White Matter Hyperintensity as a Source of Vascular Dementia or a Comorbidity to Alzheimer's Disease.
    Curr Alzheimer Res. 2021 Apr 22. pii: CAR-EPUB-115443.
    PubMed         Abstract available


    Exp Neurol

  19. MCKNIGHT I, Hart C, Park IH, Shim JW, et al
    Genes causing congenital hydrocephalus: Their chromosomal characteristics of telomere proximity and DNA compositions.
    Exp Neurol. 2021;335:113523.
    PubMed         Abstract available


    J Alzheimers Dis

  20. DAVIDOWITZ EJ, Krishnamurthy PK, Lopez P, Jimenez H, et al
    In Vivo Validation of a Small Molecule Inhibitor of Tau Self-Association in htau Mice.
    J Alzheimers Dis. 2020;73:147-161.
    PubMed         Abstract available

  21. PARVAND M, Rankin CH
    Is There a Shared Etiology of Olfactory Impairments in Normal Aging and Neurodegenerative Disease?
    J Alzheimers Dis. 2020;73:1-21.
    PubMed         Abstract available

  22. VERGOUW LJM, Bosman B, van de Beek M, Salome M, et al
    Family History is Associated with Phenotype in Dementia with Lewy Bodies.
    J Alzheimers Dis. 2020;73:269-275.
    PubMed         Abstract available

  23. TSUNODA K, Yamashita T, Osakada Y, Sasaki R, et al
    Early Emergence of Neuropsychiatric Symptoms in Cognitively Normal Subjects and Mild Cognitive Impairment.
    J Alzheimers Dis. 2020;73:209-215.
    PubMed         Abstract available

  24. BREWER GJ, Herrera RA, Philipp S, Sosna J, et al
    Age-Related Intraneuronal Aggregation of Amyloid-beta in Endosomes, Mitochondria, Autophagosomes, and Lysosomes.
    J Alzheimers Dis. 2020;73:229-246.
    PubMed         Abstract available

  25. SUNDSTROM A, Sorman DE, Hansson P, Ljungberg JK, et al
    Mental Demands at Work and Risk of Dementia.
    J Alzheimers Dis. 2020;74:735-740.
    PubMed         Abstract available

  26. ZHANG J, Hua XF, Gu J, Chen F, et al
    High Mobility Group Box 1 Ameliorates Cognitive Impairment in the 3xTg-AD Mouse Model.
    J Alzheimers Dis. 2020;74:851-864.
    PubMed         Abstract available

  27. RICHARDSON K, Wharton SB, Grossi CM, Matthews FE, et al
    Neuropathological Correlates of Cumulative Benzodiazepine and Anticholinergic Drug Use.
    J Alzheimers Dis. 2020;74:999-1009.
    PubMed         Abstract available

  28. GRONTVEDT GR, Lauridsen C, Berge G, White LR, et al
    The Amyloid, Tau, and Neurodegeneration (A/T/N) Classification Applied to a Clinical Research Cohort with Long-Term Follow-Up.
    J Alzheimers Dis. 2020;74:829-837.
    PubMed         Abstract available

  29. WATT G, Shang K, Zieba J, Olaya J, et al
    Chronic Treatment with 50 mg/kg Cannabidiol Improves Cognition and Moderately Reduces Abeta40 Levels in 12-Month-Old Male AbetaPPswe/PS1DeltaE9 Transgenic Mice.
    J Alzheimers Dis. 2020;74:937-950.
    PubMed         Abstract available

  30. ARNALDI D, Donniaquio A, Mattioli P, Massa F, et al
    Epilepsy in Neurodegenerative Dementias: A Clinical, Epidemiological, and EEG Study.
    J Alzheimers Dis. 2020 Feb 25. pii: JAD191315. doi: 10.3233/JAD-191315.
    PubMed         Abstract available

  31. KRESGE HA, Liu D, Gupta DK, Moore EE, et al
    Lower Left Ventricular Ejection Fraction Relates to Cerebrospinal Fluid Biomarker Evidence of Neurodegeneration in Older Adults.
    J Alzheimers Dis. 2020;74:965-974.
    PubMed         Abstract available

  32. ARFANAKIS K, Evia AM, Leurgans SE, Cardoso LFC, et al
    Neuropathologic Correlates of White Matter Hyperintensities in a Community-Based Cohort of Older Adults.
    J Alzheimers Dis. 2020;73:333-345.
    PubMed         Abstract available


    J Am Geriatr Soc

  33. LAM S, Lipton RB, Harvey DJ, Zammit AR, et al
    White matter hyperintensities and cognition across different Alzheimer's biomarker profiles.
    J Am Geriatr Soc. 2021 Apr 23. doi: 10.1111/jgs.17173.
    PubMed         Abstract available


    J Neurosci

  34. VAN SKIKE CE, Hussong SA, Hernandez SF, Banh AQ, et al
    mTOR attenuation with rapamycin reverses neurovascular uncoupling and memory deficits in mice modeling Alzheimer's disease.
    J Neurosci. 2021 Apr 20. pii: JNEUROSCI.2144-20.2021.
    PubMed         Abstract available


    MMWR Morb Mortal Wkly Rep


  35. QuickStats: Age-Adjusted Death Rates* for Alzheimer Disease(dagger) Among Adults Aged >/=65 Years, by Sex - National Vital Statistics System, United States, 1999-2019.
    MMWR Morb Mortal Wkly Rep. 2021;70:602.
    PubMed        


    Neurochem Res

  36. NAZIR S, Anwar F, Saleem U, Ahmad B, et al
    Drotaverine Inhibitor of PDE4: Reverses the Streptozotocin Induced Alzheimer's Disease in Mice.
    Neurochem Res. 2021 Apr 20. pii: 10.1007/s11064-021-03327.
    PubMed         Abstract available

  37. UDDIN MS, Sumsuzzman DM, Jeandet P, Behl T, et al
    Deciphering the Interacting Mechanisms of Circadian Disruption and Alzheimer's Disease.
    Neurochem Res. 2021 Apr 19. pii: 10.1007/s11064-021-03325.
    PubMed         Abstract available


    Neurology

  38. HAMILTON CA, Matthews FE, Donaghy PC, Taylor JP, et al
    Progression to Dementia in Mild Cognitive Impairment With Lewy Bodies or Alzheimer Disease.
    Neurology. 2021 Apr 19. pii: WNL.0000000000012024.
    PubMed         Abstract available


    Neurosci Lett

  39. ACERO G, Garay C, Venegas D, Ortega E, et al
    Novel monoclonal antibody 3B8 specifically recognizes pyroglutamate-modified amyloid beta 3-42 peptide in brain of AD patients and 3xTg-AD transgenic mice.
    Neurosci Lett. 2020;724:134876.
    PubMed         Abstract available


    Neuroscience

  40. JUNG H, Yi D, Soo Byun M, Ho Lee J, et al
    Functional Neural Correlates of the WAIS-IV Block Design Test in Older Adult with Mild Cognitive Impairment and Alzheimer's Disease.
    Neuroscience. 2021 Apr 15. pii: S0306-4522(21)00179.
    PubMed         Abstract available


    PLoS Genet

  41. MARQUILLY C, Busto GU, Leger BS, Boulanger A, et al
    Htt is a repressor of Abl activity required for APP-induced axonal growth.
    PLoS Genet. 2021;17:e1009287.
    PubMed         Abstract available

  42. BAIRD DA, Liu JZ, Zheng J, Sieberts SK, et al
    Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.
    PLoS Genet. 2021;17:e1009224.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  43. LORD J, Jermy B, Green R, Wong A, et al
    Mendelian randomization identifies blood metabolites previously linked to midlife cognition as causal candidates in Alzheimer's disease.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed         Abstract available


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