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  Alzheimer's Disease

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01.06.2026

1 Acta Neuropathol
3 Alzheimer Dis Assoc Disord
13 Alzheimers Dement
1 Br J Psychiatry
3 Exp Neurol
1 Geriatrics (Basel)
20 J Alzheimers Dis
1 J Am Geriatr Soc
1 J Neurol
7 Lancet
1 Nat Neurosci
2 Neurobiol Aging
1 Neurochem Res
1 Neurologia (Engl Ed)
1 Neurology


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Acta Neuropathol

  1. RICHARDSON TE, Cherry J, Kandoi S, Rohde SK, et al
    Neocortical tau burden determines the degree of cognitive impairment in individuals with Braak stage V neurofibrillary degeneration.
    Acta Neuropathol. 2026;151:61.
    PubMed         Abstract available


    Alzheimer Dis Assoc Disord

  2. BRANDT E, Koivisto A, Pereira P, Mustanoja E, et al
    Gut Microbiome Differences Between Early Alzheimer Disease and Idiopathic Normal Pressure Hydrocephalus.
    Alzheimer Dis Assoc Disord. 2026 May 28. doi: 10.1097/WAD.0000000000000726.
    PubMed         Abstract available

  3. KHOSRAVI F, Ashrafi M, Abroushan D, Ramezannezhad E, et al
    Serum Lipoprotein Subclasses as Predictors of Tensor-Based Morphometry Atrophy in the Alzheimer Disease Continuum: A Brief Report.
    Alzheimer Dis Assoc Disord. 2026 May 27. doi: 10.1097/WAD.0000000000000733.
    PubMed         Abstract available

  4. EL HAJ M, Boutoleau-Bretonniere C, Moustafa A, Chapelet G, et al
    Pupillometry as a Differential Indicator of Cognitive Processing in Alzheimer Disease and Behavioral Variant Frontotemporal Dementia.
    Alzheimer Dis Assoc Disord. 2026 May 26. doi: 10.1097/WAD.0000000000000725.
    PubMed         Abstract available


    Alzheimers Dement

  5. MORCILLO-NIETO AO, Franquesa-Mullerat M, Zsadanyi SE, Arriola-Infante JE, et al
    Peak width of skeletonized mean diffusivity reveals early and multifactorial white matter injury across sporadic and Down syndrome-associated Alzheimer's disease.
    Alzheimers Dement. 2026;22:e71507.
    PubMed         Abstract available

  6. WEERAWARNA PM, Jesudason CD, Lobb KL, Mason ER, et al
    Curated set of tool compounds to probe PYK2 and FAK signaling in Alzheimer's disease.
    Alzheimers Dement. 2026;22:e71508.
    PubMed         Abstract available

  7. KHORSAND B, Teichrow D, Ghanbarian E, Zheng L, et al
    Scalable markers for early cognitive decline: Plasma p-tau217, subjective cognitive concerns, and digital testing: Results from the A4/LEARN studies.
    Alzheimers Dement. 2026;22:e71505.
    PubMed         Abstract available

  8. DONLEY G, Hsiao J, Balintfy J, Silverberg N, et al
    Four decades of Alzheimer's disease discoveries, data, and research resources: The NIH Alzheimer's Disease Research Center Program.
    Alzheimers Dement. 2026;22:e71511.
    PubMed         Abstract available

  9. JIMENEZ DA, Bagnati PM, Flores-Montes RE, Fernandez ML, et al
    Recommendations for genetic counseling for individuals at risk of autosomal dominant Alzheimer's disease in Latin America.
    Alzheimers Dement. 2026;22:e71502.
    PubMed         Abstract available

  10. ALTSCHULER F, Castro-Laguardia AM, Canziani V, O'Byrne DF, et al
    Mapping the neurovascular landscape in aging and dementia: cerebral small vessel disease markers in a multicenter Latin American cohort.
    Alzheimers Dement. 2026;22:e71468.
    PubMed         Abstract available

  11. GAUR A, Wong M, Chen JJ, Kang Y, et al
    Synaptic biomarkers in Alzheimer's disease dementia and mild cognitive impairment: A systematic review and meta-analysis.
    Alzheimers Dement. 2026;22:e71501.
    PubMed         Abstract available

  12. HARDY CJD, Levett BA, Jiang J, Core LB, et al
    Non-verbal dichotic listening: A new cognitive hearing test for dementia.
    Alzheimers Dement. 2026;22:e71358.
    PubMed         Abstract available

  13. BOZIGAR M, Weuve J, Clark SN, Grady ST, et al
    Integrating noise as a risk factor in studies of Alzheimer's disease and dementia: Guidance for epidemiologic research.
    Alzheimers Dement. 2026;22:e71513.
    PubMed         Abstract available


  14. Correction to "Sex differences in Alzheimer's disease plasma biomarker levels and clinical utility".
    Alzheimers Dement. 2026;22:e71523.
    PubMed        

  15. IQBAL S, Olivares CB, Rizzo L, Parker TD, et al
    Repurposed drug prioritization pipeline for a multi-arm platform trial in clinical Alzheimer's disease.
    Alzheimers Dement. 2026;22:e71495.
    PubMed         Abstract available

  16. DEANGELIS R, Burnside L, Donnell DO, Hicken M, et al
    Social connection and cognitive health: A review of concepts, measures, and research priorities.
    Alzheimers Dement. 2026;22:e71517.
    PubMed         Abstract available

  17. MA F, Akolkar H, Benosman R, Herrup K, et al
    Behavior of neural networks in culture suggest that sporadic and genetic forms of Alzheimer's disease may not be equivalent.
    Alzheimers Dement. 2026;22:e71493.
    PubMed         Abstract available


    Br J Psychiatry

  18. HELLWIG S, Frings L, Heibel M, Schroeter N, et al
    [(18)F]Fluorodeoxyglucose position emission tomography for differential diagnosis of depressive cognitive impairment: incremental value compared with clinical diagnosis.
    Br J Psychiatry. 2026;228:332-339.
    PubMed         Abstract available


    Exp Neurol

  19. ZHANG B, Ran Z, Li XY, Wei ZH, et al
    A GPCR atlas across human microglial states in Alzheimer's disease: Insights from snRNA-seq and hiPSC models.
    Exp Neurol. 2026;403:115845.
    PubMed         Abstract available

  20. KULKARNI R, Kumari S, Sharma P, Dhapola R, et al
    Evaluation of the neuroprotective effects of ergosterol in a streptozotocin-induced Alzheimer's disease rat model: Insights into anti-inflammatory and antioxidant mechanisms.
    Exp Neurol. 2026 May 27:115853. doi: 10.1016/j.expneurol.2026.115853.
    PubMed         Abstract available

  21. LONG X, Shen R, Yang Y, Xu Y, et al
    Isoquercetin-ligustrazine co-polymorph attenuates hypoxia-accelerated Alzheimer's disease by suppressing PERK-CHOP-mediated ER stress.
    Exp Neurol. 2026 May 28:115856. doi: 10.1016/j.expneurol.2026.115856.
    PubMed         Abstract available


    Geriatrics (Basel)

  22. MAGEN E, Magen I, Merzon E, Green I, et al
    Fibromyalgia and Risk of Alzheimer's DiseaseRelated Dementia: A Nationwide Bidirectional Case-Control Study.
    Geriatrics (Basel). 2026;11:61.
    PubMed         Abstract available


    J Alzheimers Dis

  23. ISEI MO, Okeowo OM, Okoye CN, Sobodu TO, et al
    Enhancing global Alzheimer's disease drug outcomes by comprehensive African data integration.
    J Alzheimers Dis. 2026 May 26:13872877261452117. doi: 10.1177/13872877261452117.
    PubMed         Abstract available

  24. ZHAO QF, Huang LY, Zhu YK, Hu HY, et al
    YWHAG as a novel biomarker in Alzheimer's disease biological research framework.
    J Alzheimers Dis. 2026 May 25:13872877261450474. doi: 10.1177/13872877261450474.
    PubMed         Abstract available

  25. GUILLIAMS C, Abner E
    Potential biases associated with reported parental history of dementia in the Alzheimer's Disease Research Center cohorts: Implications for secondary data analyses.
    J Alzheimers Dis. 2026 May 25:13872877261450630. doi: 10.1177/13872877261450630.
    PubMed         Abstract available

  26. TRISTAO-PEREIRA C, Casquero-Veiga M, Malotaux V, Quiroz YT, et al
    Uncovering the causal link between cerebral glucose metabolism and cognitive function in Alzheimer's disease.
    J Alzheimers Dis. 2026 May 25:13872877261452181. doi: 10.1177/13872877261452181.
    PubMed         Abstract available

  27. KIM D, Jeong H, Lim HK, Ahn SM, et al
    Pharmacological targeting of the integrated stress response by 2BAct improves object recognition memory and reduces neuroinflammation in the 5xFAD model of Alzheimer's disease.
    J Alzheimers Dis. 2026 May 25:13872877261450638. doi: 10.1177/13872877261450638.
    PubMed         Abstract available

  28. DONG L, Liu C, Lv X, Song X, et al
    Visualization of perivascular spaces in Alzheimer's disease using 5.0 T MRI: A preliminary study.
    J Alzheimers Dis. 2026 May 25:13872877261451167. doi: 10.1177/13872877261451167.
    PubMed         Abstract available

  29. ZHANG T, He M, Wang Y, Gao P, et al
    Lipidomics reveals TREM2-associated dysregulation of plasma lipid metabolism in Alzheimer's disease.
    J Alzheimers Dis. 2026 May 25:13872877261450934. doi: 10.1177/13872877261450934.
    PubMed         Abstract available

  30. KANANI K, Ramakrishnan P, Neupane S, Misra M, et al
    Environmental risk and genetic susceptibility in Alzheimer's disease: Impacts on cognitive function and biomarkers.
    J Alzheimers Dis. 2026 May 25:13872877261451855. doi: 10.1177/13872877261451855.
    PubMed         Abstract available

  31. WANG X, Liu T, Guo Y, Huang M, et al
    Cerebral blood flow-iron susceptibility decoupling links cognition, amyloid pathology, and neuroinflammation in Alzheimer's disease.
    J Alzheimers Dis. 2026 May 25:13872877261452664. doi: 10.1177/13872877261452664.
    PubMed         Abstract available

  32. TAN Y, Liu Q, Wu C, Zhang C, et al
    Comparative long-term outcomes of home-based versus institutional care in Alzheimer's disease.
    J Alzheimers Dis. 2026 May 29:13872877261451155. doi: 10.1177/13872877261451155.
    PubMed         Abstract available

  33. MILLER JB, Rhoads T, Vintimilla R, Petersen M, et al
    Associations between Alzheimer's disease blood biomarkers and neighborhood disadvantage: A HABS-HD community cohort study.
    J Alzheimers Dis. 2026 May 29:13872877261452660. doi: 10.1177/13872877261452660.
    PubMed         Abstract available

  34. HE X, Liu W, Liu R, Li B, et al
    Exploratory study on the synergistic use of plasma neurofilament light chain, phosphorylated Tau181, and retinal examination for assessing the risk of Alzheimer's disease and mild cognitive impairment.
    J Alzheimers Dis. 2026 May 29:13872877261453611. doi: 10.1177/13872877261453611.
    PubMed         Abstract available

  35. KAPOOR A, Nguyen AD, Joyce JL, Gaubert A, et al
    Biomarkers of angiogenesis in Alzheimer's disease: Systematic review and meta-analysis.
    J Alzheimers Dis. 2026 May 29:13872877261453391. doi: 10.1177/13872877261453391.
    PubMed         Abstract available

  36. KIM JP, Lee H, Kim BH, Kang H, et al
    Genetically prioritized druggable targets for amyloid-beta pathology highlight ACE as a therapeutic candidate in Alzheimer's disease.
    J Alzheimers Dis. 2026 May 29:13872877261454540. doi: 10.1177/13872877261454540.
    PubMed         Abstract available

  37. WANG Y
    Mesenchymal stem cell-mediated regulation of neuroinflammation and amyloid-beta clearance: A promising therapeutic strategy for Alzheimer's disease.
    J Alzheimers Dis. 2026 May 27:13872877261451894. doi: 10.1177/13872877261451894.
    PubMed         Abstract available

  38. HAO L, Xing Y, Han Y
    Status of diagnosis, treatment, and care of Alzheimer's disease continuum in China: A survey-based analysis.
    J Alzheimers Dis. 2026 May 27:13872877261453551. doi: 10.1177/13872877261453551.
    PubMed         Abstract available

  39. AL-SALAHAT A, Abdul Jabbar AB, Kennedy K, Song A, et al
    Early-onset Alzheimer's disease mortality in the United States: A population-based study of trends and disparities, 2015-2024.
    J Alzheimers Dis. 2026 May 27:13872877261453030. doi: 10.1177/13872877261453030.
    PubMed         Abstract available

  40. IGA JI, Suzuki J, Matsushita T, Yoshino Y, et al
    Peripheral immune and vascular inflammatory signatures precede Alzheimer's disease onset: A serum proteomic study.
    J Alzheimers Dis. 2026 May 27:13872877261453034. doi: 10.1177/13872877261453034.
    PubMed         Abstract available

  41. YANG X, Gao Y, Zhang M, Pan J, et al
    The emerging role of oligodendrocytes in Alzheimer's disease: Integrating bibliometric insights with molecular pathogenesis.
    J Alzheimers Dis. 2026 May 27:13872877261450636. doi: 10.1177/13872877261450636.
    PubMed         Abstract available

  42. PILONIETA G, Pisu M, Martin RC, Shan L, et al
    Hospitalizations and long-term care for older adults with Alzheimer's disease and related dementia: Differences across geographic regions of the United States.
    J Alzheimers Dis. 2026 May 27:13872877261453901. doi: 10.1177/13872877261453901.
    PubMed         Abstract available


    J Am Geriatr Soc

  43. HU Z, Raji MA, Shan Y, Tzeng HM, et al
    Annual Wellness Visits and Timing of Advance Care Planning Among Medicare Beneficiaries With Cognitive Impairment.
    J Am Geriatr Soc. 2026;74:1429-1438.
    PubMed         Abstract available


    J Neurol

  44. MORBELLI SD, Bozzali M, Cagnin A, Cecchin D, et al
    Precision pathways: optimising amyloid PET for sustainable Alzheimer's disease care.
    J Neurol. 2026;273:340.
    PubMed         Abstract available


    Lancet

  45. SERRANO-POZO A, Escott-Price V, Grinberg LT, Pascoal T, et al
    Alzheimer's disease.
    Lancet. 2026;407:2241-2262.
    PubMed         Abstract available

  46. POVALA G, Bellaver B, Lussier FZ, Amaral L, et al
    Comparison of [18F]flortaucipir and [18F]MK6240 for the detection of tau pathology in Alzheimer's disease (HEAD): a multicentre, prospective, cross-sectional, within-participant study.
    Lancet. 2026;407:2217-2226.
    PubMed         Abstract available

  47. ROSENBERG A, Ngandu T
    Plasma biomarkers for Alzheimer's disease among middle-aged individuals.
    Lancet. 2026;407:2146-2147.
    PubMed        

  48. THERRIAULT J
    Advancing tau-PET imaging in Alzheimer's disease.
    Lancet. 2026;407:2148-2149.
    PubMed        

  49. SUAREZ-CALVET M, Salvado G, de Fortuny BB, Del Campo M, et al
    Blood biomarkers for Alzheimer's disease: from detection to decisions.
    Lancet. 2026;407:2151-2154.
    PubMed        

  50. MCLELLAN F
    Reisa Sperling: getting ahead of Alzheimer's disease.
    Lancet. 2026;407:2164.
    PubMed        

  51. JIANG X, Hoang TD, Shaw LM, Jacobs DR Jr, et al
    Alzheimer's disease neuropathology plasma biomarkers and cognition in midlife: a community-based cohort study.
    Lancet. 2026;407:2208-2216.
    PubMed         Abstract available


    Nat Neurosci


  52. An unexpected molecular explanation for how tau aggregation begins in Alzheimer's disease.
    Nat Neurosci. 2026 May 29. doi: 10.1038/s41593-026-02298.
    PubMed        


    Neurobiol Aging

  53. GONZALEZ MM, Magondu B, Rowan MJM, Forest CR, et al
    Regional alterations of parvalbumin interneurons in human App knock-in mouse model of Alzheimer's disease pathology.
    Neurobiol Aging. 2026;166:41-49.
    PubMed         Abstract available

  54. COULTER K, Dash T, Best T, Grant N, et al
    Multilingualism and cognitive reserve in older adults with, or at risk for, Alzheimer's disease: Evidence from resting-state functional connectivity.
    Neurobiol Aging. 2026;166:50-57.
    PubMed         Abstract available


    Neurochem Res

  55. GERASIMOV KA, Ignasheva YE, Dobryakova YV, Korotkova TA, et al
    Overexpression of WNT3a in the Hippocampus Can Partly Alleviate Deficits in Animal Models of Alzheimer's Disease.
    Neurochem Res. 2026;51:174.
    PubMed         Abstract available


    Neurologia (Engl Ed)

  56. SANCHEZ-VALLE R, Alcolea D, Ferrer GA, Balasa M, et al
    Appropriate use recommendations of the Spanish Society of Neurology's Behavioural Neurology and Dementia Study Group on anti-amyloid antibodies in the treatment of Alzheimer disease.
    Neurologia (Engl Ed). 2026 May 26:502075. doi: 10.1016/j.nrleng.2026.502075.
    PubMed         Abstract available


    Neurology

  57. URSO D, Giannoni-Luza S, Gnoni V, Giugno A, et al
    Incidence of Dementia With Lewy Bodies in Salento, Italy: A Population-Based Study.
    Neurology. 2026;106:e218150.
    PubMed         Abstract available


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