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  Alzheimer's Disease

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24.06.2024

3 Acta Neuropathol
9 Alzheimers Dement
1 Am J Alzheimers Dis Other Demen
1 BMC Geriatr
1 BMJ
1 Brain Res
2 Drugs
5 J Alzheimers Dis
1 J Am Geriatr Soc
2 J Neurol
3 N Engl J Med
1 Nat Med
1 Nat Neurosci
1 Neurobiol Dis
1 Neurochem Res
1 Neurology


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Acta Neuropathol

  1. HOGLUND Z, Ruiz-Uribe N, Del Sastre E, Woost B, et al
    Brain vasculature accumulates tau and is spatially related to tau tangle pathology in Alzheimer's disease.
    Acta Neuropathol. 2024;147:101.
    PubMed         Abstract available

  2. WOODWORTH DC, Nguyen KM, Sordo L, Scambray KA, et al
    Comprehensive assessment of TDP-43 neuropathology data in the National Alzheimer's Coordinating Center database.
    Acta Neuropathol. 2024;147:103.
    PubMed         Abstract available

  3. OLLEN-BITTLE N, Pejhan S, Pasternak SH, Keene CD, et al
    Co-registration of MALDI-MSI and histology demonstrates gangliosides co-localize with amyloid beta plaques in Alzheimer's disease.
    Acta Neuropathol. 2024;147:105.
    PubMed         Abstract available


    Alzheimers Dement

  4. SILBERT LC, Roese NE, Krajbich V, Hurworth J, et al
    White matter hyperintensities and the surrounding normal appearing white matter are associated with water channel disruption in the oldest old.
    Alzheimers Dement. 2024;20:3839-3851.
    PubMed         Abstract available

  5. WANG J, Huang Q, He K, Li J, et al
    Presynaptic density determined by SV2A PET is closely associated with postsynaptic metabotropic glutamate receptor 5 availability and independent of amyloid pathology in early cognitive impairment.
    Alzheimers Dement. 2024;20:3876-3888.
    PubMed         Abstract available

  6. ARANHA MR, Montal V, van den Brink H, Pegueroles J, et al
    Cortical microinfarcts in adults with Down syndrome assessed with 3T-MRI.
    Alzheimers Dement. 2024;20:3906-3917.
    PubMed         Abstract available

  7. SCHNEIDER C, Prokopiou PC, Papp KV, Engels-Dominguez N, et al
    Atrophy links lower novelty-related locus coeruleus connectivity to cognitive decline in preclinical AD.
    Alzheimers Dement. 2024;20:3958-3971.
    PubMed         Abstract available

  8. ZHU Y, Park S, Kolady R, Zha W, et al
    A systematic review/meta-analysis of prevalence and incidence rates illustrates systemic underrepresentation of individuals racialized as Asian and/or Asian-American in ADRD research.
    Alzheimers Dement. 2024;20:4315-4330.
    PubMed         Abstract available

  9. COOPER JG, Ghodsi M, Stukas S, Leach S, et al
    APOE epsilon4 carrier status modifies plasma p-tau181 concentrations in cognitively healthy super-seniors.
    Alzheimers Dement. 2024;20:4373-4380.
    PubMed         Abstract available

  10. YAO Y, Muench M, Alle T, Zhang B, et al
    A small-molecule microtubule-stabilizing agent safely reduces Abeta plaque and tau pathology in transgenic mouse models of Alzheimer's disease.
    Alzheimers Dement. 2024 Jun 17. doi: 10.1002/alz.13875.
    PubMed         Abstract available

  11. HAMLIN D, Ryall C, Turner C, Faull RLM, et al
    Characterization of neurofibrillary tangle immunophenotype signatures to classify tangle maturity in Alzheimer's disease.
    Alzheimers Dement. 2024 Jun 17. doi: 10.1002/alz.13922.
    PubMed         Abstract available

  12. LI Q, Su S, Feng Y, Jia M, et al
    Potential role of blood pressure variability and plasma neurofilament light in the mechanism of comorbidity between Alzheimer's disease and cerebral small vessel disease.
    Alzheimers Dement. 2024 Jun 19. doi: 10.1002/alz.14056.
    PubMed         Abstract available


    Am J Alzheimers Dis Other Demen

  13. CARRARD S, Eyer S, Hilfiker R, Mittaz Hager AG, et al
    Adapted Home-Based Exercises in Dementia: An Exploratory Pre-post Pilot and Feasibility Study.
    Am J Alzheimers Dis Other Demen. 2024;39:15333175241263741.
    PubMed         Abstract available


    BMC Geriatr

  14. WANG X, Zhou S, Ye N, Li Y, et al
    Predictive models of Alzheimer's disease dementia risk in older adults with mild cognitive impairment: a systematic review and critical appraisal.
    BMC Geriatr. 2024;24:531.
    PubMed         Abstract available


    BMJ

  15. DYER O
    Donanemab: FDA experts recommend approval of Alzheimer's drug.
    BMJ. 2024;385:q1327.
    PubMed        


    Brain Res

  16. DE LOURDES SIGNORINI-SOUZA I, Tureck LV, Batistela MS, Coutinho de Almeida R, et al
    The potential of five c-miRNAs as serum biomarkers for Late-Onset Alzheimer's disease diagnosis: miR-10a-5p, miR-29b-2-5p, miR-125a-5p, miR-342-3p, and miR-708-5p.
    Brain Res. 2024 Jun 14:149090. doi: 10.1016/j.brainres.2024.149090.
    PubMed         Abstract available


    Drugs

  17. HEY JA, Yu JY, Abushakra S, Schaefer JF, et al
    Analysis of Cerebrospinal Fluid, Plasma beta-Amyloid Biomarkers, and Cognition from a 2-Year Phase 2 Trial Evaluating Oral ALZ-801/Valiltramiprosate in APOE4 Carriers with Early Alzheimer's Disease Using Quantitative Systems Pharmacology Model.
    Drugs. 2024 Jun 20. doi: 10.1007/s40265-024-02068.
    PubMed         Abstract available

  18. HEY JA, Abushakra S, Blennow K, Reiman EM, et al
    Effects of Oral ALZ-801/Valiltramiprosate on Plasma Biomarkers, Brain Hippocampal Volume, and Cognition: Results of 2-Year Single-Arm, Open-Label, Phase 2 Trial in APOE4 Carriers with Early Alzheimer's Disease.
    Drugs. 2024 Jun 20. doi: 10.1007/s40265-024-02067.
    PubMed         Abstract available


    J Alzheimers Dis

  19. PERRY G, Castellani R
    Alzheimer's Disease: Are We There Yet?
    J Alzheimers Dis. 2024 Jun 20. doi: 10.3233/JAD-249012.
    PubMed        

  20. GARERI P, Cotroneo AM, Montella R, Gaglianone M, et al
    Citicoline: A Cholinergic Precursor with a Pivotal Role in Dementia and Alzheimer's Disease.
    J Alzheimers Dis. 2024 Jun 15. doi: 10.3233/JAD-240497.
    PubMed         Abstract available

  21. LOBUE C, McClintock SM, Chiang HS, Helphrey J, et al
    A Critical Review of Noninvasive Brain Stimulation Technologies in Alzheimer's Dementia and Primary Progressive Aphasia.
    J Alzheimers Dis. 2024 Jun 20. doi: 10.3233/JAD-240230.
    PubMed         Abstract available

  22. SAKHAROVA T, Mao S, Osadchuk M
    Updated Models of Alzheimer's Disease with Deep Neural Networks.
    J Alzheimers Dis. 2024 Jun 21. doi: 10.3233/JAD-240183.
    PubMed         Abstract available

  23. HU Y, Wang X, Zhao Z, Liu M, et al
    The Downregulation of ITGAX Exacerbates Amyloid-beta Plaque Deposition in Alzheimer's Disease by Increasing Polarization of M1 Microglia.
    J Alzheimers Dis. 2024 Jun 20. doi: 10.3233/JAD-240118.
    PubMed         Abstract available


    J Am Geriatr Soc

  24. JACOBSON M, Ferido P, Zissimopoulos J
    Health care utilization before and after a dementia diagnosis in Medicare Advantage versus traditional Medicare.
    J Am Geriatr Soc. 2024;72:1856-1866.
    PubMed         Abstract available


    J Neurol

  25. LI KY, Chien CF, Huang LC, Lim K, et al
    Exploring the impact of 40 Hz multi-luminaire light exposure in Alzheimer's dementia: insights from a convenient sampling, non-randomized case-control study.
    J Neurol. 2024 Jun 17. doi: 10.1007/s00415-024-12486.
    PubMed         Abstract available

  26. FOXE D, Irish M, Carrick J, Cheung SC, et al
    Correction to: Visuospatial working memory in behavioural variant frontotemporal dementia: a comparative analysis with Alzheimer's disease using the box task.
    J Neurol. 2024 Jun 21. doi: 10.1007/s00415-024-12483.
    PubMed        


    N Engl J Med

  27. STEFANSSON H, Walters GB, Sveinbjornsson G, Tragante V, et al
    Homozygosity for R47H in TREM2 and the Risk of Alzheimer's Disease.
    N Engl J Med. 2024;390:2217-2219.
    PubMed        

  28. HARDY J
    Protection against Alzheimer's Disease with APOE Christchurch Variant - How?
    N Engl J Med. 2024;390:2212-2213.
    PubMed        

  29. QUIROZ YT, Aguillon D, Aguirre-Acevedo DC, Vasquez D, et al
    APOE3 Christchurch Heterozygosity and Autosomal Dominant Alzheimer's Disease.
    N Engl J Med. 2024;390:2156-2164.
    PubMed         Abstract available


    Nat Med

  30. FORTEA J, Pegueroles J, Alcolea D, Belbin O, et al
    Publisher Correction: APOE4 homozygosity represents a distinct genetic form of Alzheimer's disease.
    Nat Med. 2024 Jun 17. doi: 10.1038/s41591-024-03127.
    PubMed        


    Nat Neurosci

  31. NARASIMHAN S, Holtzman DM, Apostolova LG, Cruchaga C, et al
    Apolipoprotein E in Alzheimer's disease trajectories and the next-generation clinical care pathway.
    Nat Neurosci. 2024 Jun 19. doi: 10.1038/s41593-024-01669.
    PubMed         Abstract available


    Neurobiol Dis

  32. CHANDRASHEKAR DV, Roules GC, Jagadeesan N, Panchal UR, et al
    Hepatic LRP-1 plays an important role in amyloidosis in Alzheimer's disease mice: Potential role in chronic heavy alcohol feeding.
    Neurobiol Dis. 2024 Jun 15:106570. doi: 10.1016/j.nbd.2024.106570.
    PubMed         Abstract available


    Neurochem Res

  33. OLIVEIRA-LIMA OC, de Carvalho GA, do Prado Assuncao L, Bailao AM, et al
    GlyT1 Inhibition by NFPS Promotes Neuroprotection in Amyloid-beta-Induced Alzheimer's Disease Animal Model.
    Neurochem Res. 2024 Jun 18. doi: 10.1007/s11064-024-04190.
    PubMed         Abstract available


    Neurology

  34. XIA Y, Dore V, Fripp J, Bourgeat P, et al
    Association of Basal Forebrain Atrophy With Cognitive Decline in Early Alzheimer Disease.
    Neurology. 2024;103:e209626.
    PubMed         Abstract available


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