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Alzheimer's Disease

Free Subscription 13.09.2021 6 Alzheimers Dement 3 Curr Alzheimer Res 17 J Alzheimers Dis 1 J Am Geriatr Soc 3 J Biol Chem 1 JAMA 2 Lancet 1 N Engl J Med 1 Nat Med 1 Nervenarzt 3 Neurol Clin Pract 4 Neurologia (Engl Ed) 1 Neurosci Lett 2 Proc Natl Acad Sci U S A

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Alzheimers Dement

1. REN RJ, Huang Q, Xu G, Gu K, et al
   Association between Alzheimer's disease and risk of cancer: A retrospective cohort study in Shanghai, China.
   Alzheimers Dement. 2021 Sep 5. doi: 10.1002/alz.12436.
   PubMed         Abstract available
   
   
2. MARTERSTECK A, Sridhar J, Coventry C, Weintraub S, et al
   Relationships among tau burden, atrophy, age, and naming in the aphasic variant of Alzheimer's disease.
   Alzheimers Dement. 2021 Sep 8. doi: 10.1002/alz.12445.
   PubMed         Abstract available
   
   
3. ZHANG L, Du Rietz E, Kuja-Halkola R, Dobrosavljevic M, et al
   Attention-deficit/hyperactivity disorder and Alzheimer's disease and any dementia: A multi-generation cohort study in Sweden.
   Alzheimers Dement. 2021 Sep 9. doi: 10.1002/alz.12462.
   PubMed         Abstract available
   
   
4. CHATTERJEE P, Pedrini S, Ashton NJ, Tegg M, et al
   Diagnostic and prognostic plasma biomarkers for preclinical Alzheimer's disease.
   Alzheimers Dement. 2021 Sep 8. doi: 10.1002/alz.12447.
   PubMed         Abstract available
   
   
5. LOGSDON AF, Francis KL, Richardson NE, Hu SJ, et al
   Decoding perineuronal net glycan sulfation patterns in the Alzheimer's disease brain.
   Alzheimers Dement. 2021 Sep 5. doi: 10.1002/alz.12451.
   PubMed         Abstract available
   
   
6. MA Y, Yu L, Olah M, Smith R, et al
   Epigenomic features related to microglia are associated with attenuated effect of APOE epsilon4 on Alzheimer's disease risk in humans.
   Alzheimers Dement. 2021 Sep 5. doi: 10.1002/alz.12425.
   PubMed         Abstract available
   
   

   
   Curr Alzheimer Res

7. SAHA S, Singh S, Prasad S, Mittal A, et al
   Gut Microbiota and Alzheimer's Disease: Experimental Evidence and Clinical Reality.
   Curr Alzheimer Res. 2021 Sep 7. pii: CAR-EPUB-117739.
   PubMed         Abstract available
   
   
8. NEZHADMOGHADAM F, Martinez-Torteya A, Trevino V, Martinez E, et al
   Robust Discovery of Mild Cognitive Impairment Subtypes and Their Risk of Alzheimer's Disease Conversion Using Unsupervised Machine Learning and Gaussian Mixture Modeling.
   Curr Alzheimer Res. 2021 Aug 31. pii: CAR-EPUB-117574.
   PubMed         Abstract available
   
   
9. ZHOU R, Chen LL, Yang H, Li L, et al
   Effect of High Cholesterol Regulation of LRP1 and RAGE on Abeta Transport Across the Blood-brain Barrier in Alzheimer's Disease.
   Curr Alzheimer Res. 2021 Sep 5. pii: CAR-EPUB-117691.
   PubMed         Abstract available
   
   

   
   J Alzheimers Dis

10. ZHANG XQ, Xu L, Yang SY, Hu LB, et al
    Reduced Synaptic and Intrinsic Excitability of a Subtype of Pyramidal Neurons in the Medial Prefrontal Cortex in a Mouse Model of Alzheimer's Disease.
    J Alzheimers Dis. 2021 Sep 2. pii: JAD210585. doi: 10.3233/JAD-210585.
    PubMed         Abstract available
    
    
11. HE F, Zhang Y, Wu X, Li Y, et al
    Early Microstructure Changes of White Matter Fiber Bundles in Patients with Amnestic Mild Cognitive Impairment Predicts Progression of Mild Cognitive Impairment to Alzheimer's Disease.
    J Alzheimers Dis. 2021 Sep 1. pii: JAD210495. doi: 10.3233/JAD-210495.
    PubMed         Abstract available
    
    
12. HADDAD M, Perrotte M, Ben Khedher MR, Madec E, et al
    Levels of Receptor for Advanced Glycation End Products and Glyoxalase-1 in the Total Circulating Extracellular Vesicles from Mild Cognitive Impairment and Different Stages of Alzheimer's Disease Patients.
    J Alzheimers Dis. 2021 Sep 1. pii: JAD210441. doi: 10.3233/JAD-210441.
    PubMed         Abstract available
    
    
13. SUH SW, Kim YJ, Kwak KP, Kim K, et al
    A 9-Year Comparison of Dementia Prevalence in Korea: Results of NaSDEK 2008 and 2017.
    J Alzheimers Dis. 2021;81:821-831.
    PubMed         Abstract available
    
    
14. LIU X, Chen KL, Wang Y, Huang YY, et al
    A Novel ITM2B Mutation Associated with Familial Chinese Dementia.
    J Alzheimers Dis. 2021;81:499-505.
    PubMed         Abstract available
    
    
15. SCHMIDT SL, Boechat YEM, Schmidt GJ, Nicaretta D, et al
    Clinical Utility of a Reaction-Time Attention Task in the Evaluation of Cognitive Impairment in Elderly with High Educational Disparity.
    J Alzheimers Dis. 2021;81:691-697.
    PubMed         Abstract available
    
    
16. MARTINEZ-FLOREZ JF, Osorio JD, Cediel JC, Rivas JC, et al
    Short-Term Memory Binding Distinguishing Amnestic Mild Cognitive Impairment from Healthy Aging: A Machine Learning Study.
    J Alzheimers Dis. 2021;81:729-742.
    PubMed         Abstract available
    
    
17. KANATOME A, Ano Y, Shinagawa K, Ide Y, et al
    beta-Lactolin Enhances Neural Activity, Indicated by Event-Related P300 Amplitude, in Healthy Adults: A Randomized Controlled Trial.
    J Alzheimers Dis. 2021;81:787-796.
    PubMed         Abstract available
    
    
18. WANG X, Bui H, Vemuri P, Graff-Radford J, et al
    Lipidomic Network of Mild Cognitive Impairment from the Mayo Clinic Study of Aging.
    J Alzheimers Dis. 2021;81:533-543.
    PubMed         Abstract available
    
    
19. HALAAS NB, Zetterberg H, Idland AV, Knapskog AB, et al
    Cerebrospinal Fluid Concentration of Neurogranin in Hip Fracture Patients with Delirium.
    J Alzheimers Dis. 2021;81:667-677.
    PubMed         Abstract available
    
    
20. HIRAO K, Yamashita F, Tsugawa A, Haime R, et al
    Association of White Matter Hyperintensity Progression with Cognitive Decline in Patients with Amnestic Mild Cognitive Impairment.
    J Alzheimers Dis. 2021;80:877-883.
    PubMed         Abstract available
    
    
21. YUAN L, Zhang J, Guo JH, Holscher C, et al
    DAla2-GIP-GLU-PAL Protects Against Cognitive Deficits and Pathology in APP/PS1 Mice by Inhibiting Neuroinflammation and Upregulating cAMP/PKA/CREB Signaling Pathways.
    J Alzheimers Dis. 2021;80:695-713.
    PubMed         Abstract available
    
    
22. SAHU B, Mackos AR, Floden AM, Wold LE, et al
    Particulate Matter Exposure Exacerbates Amyloid-beta Plaque Deposition and Gliosis in APP/PS1 Mice.
    J Alzheimers Dis. 2021;80:761-774.
    PubMed         Abstract available
    
    
23. CALDIERARO MA, Laufer-Silva T, Cassano P
    Dosimetry and Clinical Efficacy of Transcranial Photobiomodulation for Major Depression Disorder: Could they Guide Dosimetry for Alzheimer's Disease?
    J Alzheimers Dis. 2021 Sep 1. pii: JAD210586. doi: 10.3233/JAD-210586.
    PubMed         Abstract available
    
    
24. KATZOUROU I, Leonenko G, Ivanov D, Meggy A, et al
    Cognitive Decline in Alzheimer's Disease Is Not Associated with APOE.
    J Alzheimers Dis. 2021 Aug 30. pii: JAD210685. doi: 10.3233/JAD-210685.
    PubMed         Abstract available
    
    
25. FARACE P, Tamburin S
    Combining Low-Dose Radiation Therapy and Magnetic Resonance Guided Focused Ultrasound to Reduce Amyloid-beta Deposition in Alzheimer's Disease.
    J Alzheimers Dis. 2021 Aug 30. pii: JAD215041. doi: 10.3233/JAD-215041.
    PubMed         Abstract available
    
    
26. QUINT WH, Matecko-Burmann I, Schilcher I, Loffler T, et al
    Bispecific Tau Antibodies with Additional Binding to C1q or Alpha-Synuclein.
    J Alzheimers Dis. 2021;80:813-829.
    PubMed         Abstract available
    
    

    
    J Am Geriatr Soc

27. HOLLENBECK BK, Dunn RL, Sukul D, Modi PK, et al
    Aortic valve replacement among patients with Alzheimer's disease and related dementias.
    J Am Geriatr Soc. 2021 Sep 8. doi: 10.1111/jgs.17432.
    PubMed         Abstract available
    
    

    
    J Biol Chem

28. ROBERTS JP, Stokoe SA, Sathler MF, Nichols RA, et al
    Selective coactivation of alpha7- and alpha4beta2-nicotinic acetylcholine receptors reverses beta-amyloid-induced synaptic dysfunction.
    J Biol Chem. 2021;296:100402.
    PubMed         Abstract available
    
    
29. NIES SH, Takahashi H, Herber CS, Huttner A, et al
    Spreading of Alzheimer Tau seeds is enhanced by aging and template matching with limited impact of amyloid-beta.
    J Biol Chem. 2021 Sep 1:101159. doi: 10.1016/j.jbc.2021.101159.
    PubMed         Abstract available
    
    
30. KONIG AS, Rosener NS, Gremer L, Tusche M, et al
    Structural details of amyloid beta oligomers in complex with human prion protein as revealed by solid-state MAS NMR spectroscopy.
    J Biol Chem. 2021;296:100499.
    PubMed         Abstract available
    
    

    
    JAMA

31. ANDERSON TS, Ayanian JZ, Souza J, Landon BE, et al
    Representativeness of Participants Eligible to Be Enrolled in Clinical Trials of Aducanumab for Alzheimer Disease Compared With Medicare Beneficiaries With Alzheimer Disease and Mild Cognitive Impairment.
    JAMA. 2021 Sep 9. pii: 2784225. doi: 10.1001/jama.2021.15286.
    PubMed        
    
    

    
    Lancet

32. SCHELTENS P
    Responding to responsive behaviour in Alzheimer's disease - Author's reply.
    Lancet. 2021;398:842.
    PubMed        
    
    
33. O'NEILL D, Kennelly S
    Responding to responsive behaviour in Alzheimer's disease.
    Lancet. 2021;398:842.
    PubMed        
    
    

    
    N Engl J Med

34. ALEXANDER GC, Knopman DS, Emerson SS, Ovbiagele B, et al
    Revisiting FDA Approval of Aducanumab.
    N Engl J Med. 2021;385:769-771.
    PubMed        
    
    

    
    Nat Med

35. JABBARI E, Duff KE
    Tau-targeting antibody therapies: too late, wrong epitope or wrong target?
    Nat Med. 2021;27:1341-1342.
    PubMed        
    
    

    
    Nervenarzt

36. HAGER K
    [First causally effective drug against Alzheimer's? : The FDA approves aducanumab].
    Nervenarzt. 2021 Sep 7. pii: 10.1007/s00115-021-01182.
    PubMed        
    
    

    
    Neurol Clin Pract

37. MARCUM ZA, Chang CY, Barthold D, Holmes HM, et al
    Industry Payments to Physicians and Prescribing Branded Memantine and Donepezil Combination.
    Neurol Clin Pract. 2021;11:181-187.
    PubMed         Abstract available
    
    
38. REESE JP
    Prescription of Memantine/Donepezil: Influence of Industry Payments?
    Neurol Clin Pract. 2021;11:179-180.
    PubMed        
    
    
39. VENDITTO JG, Bender E, Lichtenstein ML
    Psychosis in a Middle-aged Woman: A Case of Presenilin-1 p.Gly206Ala Alzheimer Disease.
    Neurol Clin Pract. 2021;11:e573-e575.
    PubMed        
    
    

    
    Neurologia (Engl Ed)

40. MAR J, Arrospide A, Soto-Gordoa M, Machon M, et al
    Validity of a computerised population registry of dementia based on clinical databases.
    Neurologia (Engl Ed). 2021;36:418-425.
    PubMed         Abstract available
    
    
41. LACAMPRE R, Perez Perez RM, Pinol-Ripoll G
    Understanding of legal aspects of Alzheimer disease among caregivers, medical students, and healthcare professionals.
    Neurologia (Engl Ed). 2021;36:34-38.
    PubMed         Abstract available
    
    
42. VILLAREJO GALENDE A, Eimil Ortiz M, Llamas Velasco S, Llanero Luque M, et al
    Report by the Spanish Foundation of the Brain on the social impact of Alzheimer disease and other types of dementia.
    Neurologia (Engl Ed). 2021;36:39-49.
    PubMed         Abstract available
    
    
43. ALLEGRI RF, Chrem Mendez P, Russo MJ, Cohen G, et al
    Biomarkers of Alzheimer's disease in mild cognitive impairment: Experience in a memory clinic from Latin America.
    Neurologia (Engl Ed). 2021;36:201-208.
    PubMed         Abstract available
    
    

    
    Neurosci Lett

44. RADAGHDAM S, Karamad V, Nourazarian A, Shademan B, et al
    Molecular mechanisms of sex hormones in the development and progression of Alzheimer's disease.
    Neurosci Lett. 2021 Sep 6:136221. doi: 10.1016/j.neulet.2021.136221.
    PubMed         Abstract available
    
    

    
    Proc Natl Acad Sci U S A

45. HOU Y, Wei Y, Lautrup S, Yang B, et al
    NAD(+) supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer's disease via cGAS-STING.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed         Abstract available
    
    
46. IPPATI S, Deng Y, van der Hoven J, Heu C, et al
    Rapid initiation of cell cycle reentry processes protects neurons from amyloid-beta toxicity.
    Proc Natl Acad Sci U S A. 2021;118.
    PubMed         Abstract available
    
    

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