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  Alzheimer's Disease

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20 Alzheimers Dement
1 Am J Geriatr Psychiatry
1 BMC Neurol
1 Brain Res
12 J Alzheimers Dis
2 J Am Geriatr Soc
3 J Neurochem
2 J Neurosci
2 Lancet Neurol
2 N Engl J Med
1 Nat Med
1 Nat Rev Neurol
1 Nat Rev Neurosci
2 Neurobiol Aging
1 Neurochem Res
3 Neurology

  Retrieve available abstracts of this week’s articles:
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Single Articles

    Alzheimers Dement

  1. Alzheimer's Association and ASNR announce recipients of imaging grants.
    Alzheimers Dement. 2024;20:1476-1477.

  2. XICOTA L, Cosentino S, Vardarajan B, Mayeux R, et al
    Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.
    Alzheimers Dement. 2024 Feb 21. doi: 10.1002/alz.13718.
    PubMed         Abstract available

  3. WOLTERS FJ, Labrecque JA
    Potential impact of unblinding on observed treatment effects in Alzheimer's disease trials.
    Alzheimers Dement. 2024 Feb 21. doi: 10.1002/alz.13690.
    PubMed         Abstract available

  4. FERGUSON CM, Hildebrand S, Godinho BMDC, Buchwald J, et al
    Silencing Apoe with divalent-siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease.
    Alzheimers Dement. 2024 Feb 20. doi: 10.1002/alz.13703.
    PubMed         Abstract available

  5. ORTEGA-CRUZ D, Bress KS, Gazula H, Rabano A, et al
    Three-dimensional histology reveals dissociable human hippocampal long-axis gradients of Alzheimer's pathology.
    Alzheimers Dement. 2024 Feb 18. doi: 10.1002/alz.13695.
    PubMed         Abstract available

  6. CLARK AL, Thomas KR, Ortega N, Haley AP, et al
    Empirically derived psychosocial-behavioral phenotypes in Black/African American and Hispanic/Latino older adults enrolled in HABS-HD: Associations with AD biomarkers and cognitive outcomes.
    Alzheimers Dement. 2024;20:1360-1373.
    PubMed         Abstract available

  7. EISSMAN JM, Archer DB, Mukherjee S, Lee ML, et al
    Sex-specific genetic architecture of late-life memory performance.
    Alzheimers Dement. 2024;20:1250-1267.
    PubMed         Abstract available

  8. SLEE MG, Rainey-Smith SR, Villemagne VL, Doecke JD, et al
    Physical activity and brain amyloid beta: A longitudinal analysis of cognitively unimpaired older adults.
    Alzheimers Dement. 2024;20:1350-1359.
    PubMed         Abstract available

  9. COGSWELL PM, Lundt ES, Therneau TM, Wiste HJ, et al
    Modeling the temporal evolution of plasma p-tau in relation to amyloid beta and tau PET.
    Alzheimers Dement. 2024;20:1225-1238.
    PubMed         Abstract available

  10. BUTTS B, Huang H, Hu WT, Kehoe PG, et al
    sPDGFRbeta and neuroinflammation are associated with AD biomarkers and differ by race: The ASCEND Study.
    Alzheimers Dement. 2024;20:1175-1189.
    PubMed         Abstract available

  11. CHEN H, Dunk MM, Wang B, Zhao M, et al
    Associations of the Mediterranean-DASH Intervention for Neurodegenerative Delay diet with brain structural markers and their changes.
    Alzheimers Dement. 2024;20:1190-1200.
    PubMed         Abstract available

  12. WOO MS, Tissot C, Lantero-Rodriguez J, Snellman A, et al
    Plasma pTau-217 and N-terminal tau (NTA) enhance sensitivity to identify tau PET positivity in amyloid-beta positive individuals.
    Alzheimers Dement. 2024;20:1166-1174.
    PubMed         Abstract available

  13. ACKLEY SF, Wang J, Chen R, Power MC, et al
    Estimated effects of amyloid reduction on cognitive change: A Bayesian update across a range of priors.
    Alzheimers Dement. 2024;20:1149-1155.
    PubMed         Abstract available

  14. SANFORD SAI, Miller LVC, Vaysburd M, Keeling S, et al
    The type-I interferon response potentiates seeded tau aggregation and exacerbates tau pathology.
    Alzheimers Dement. 2024;20:1013-1025.
    PubMed         Abstract available

  15. GERMAN-CASTELAN L, Shanks HRC, Gros R, Saito T, et al
    Sex-dependent cholinergic effects on amyloid pathology: A translational study.
    Alzheimers Dement. 2024;20:995-1012.
    PubMed         Abstract available

  16. SCHWEITZER N, Li J, Thurston RC, Lopresti B, et al
    Sex-dependent alterations in hippocampal connectivity are linked to cerebrovascular and amyloid pathologies in normal aging.
    Alzheimers Dement. 2024;20:914-924.
    PubMed         Abstract available

  17. AARONSON A, Ashford MT, Jin C, Bride J, et al
    Brain Health Registry Study Partner Portal: Novel infrastructure for digital, dyadic data collection.
    Alzheimers Dement. 2024;20:846-857.
    PubMed         Abstract available

  18. MARINO C, Perez-Corredor P, O'Hare M, Heuer A, et al
    APOE Christchurch-mimetic therapeutic antibody reduces APOE-mediated toxicity and tau phosphorylation.
    Alzheimers Dement. 2024;20:819-836.
    PubMed         Abstract available

  19. TATE AE, Bouteloup V, van Maurik IS, Jean D, et al
    Predicting sojourn times across dementia disease stages, institutionalization, and mortality.
    Alzheimers Dement. 2024;20:809-818.
    PubMed         Abstract available

  20. SHI H, Koronyo Y, Fuchs DT, Sheyn J, et al
    Retinal arterial Abeta(40) deposition is linked with tight junction loss and cerebral amyloid angiopathy in MCI and AD patients.
    Alzheimers Dement. 2023;19:5185-5197.
    PubMed         Abstract available

    Am J Geriatr Psychiatry

  21. SISTI A, Gutman R, Mor V, Dionne L, et al
    Using Structured Observations to Evaluate the Effects of a Personalized Music Intervention on Agitated Behaviors and Mood in Nursing Home Residents With Dementia: Results From an Embedded, Pragmatic Randomized Controlled Trial.
    Am J Geriatr Psychiatry. 2024;32:300-311.
    PubMed         Abstract available

    BMC Neurol

  22. YE S, Roccati E, Wang W, Zhu Z, et al
    Leading determinants of incident dementia among individuals with and without the apolipoprotein E epsilon4 genotype: a retrospective cohort study.
    BMC Neurol. 2024;24:71.
    PubMed         Abstract available

    Brain Res

  23. MANTELLATTO GRIGOLI M, Pelegrini LNC, Whelan R, Cominetti MR, et al
    Present and Future of Blood-Based Biomarkers of Alzheimer's Disease: Beyond the Classics.
    Brain Res. 2024;1830:148812.
    PubMed         Abstract available

    J Alzheimers Dis

  24. FINCH CE, Burstein SM
    Dementia in the Ancient Greco-Roman World Was Minimally Mentioned.
    J Alzheimers Dis. 2024;97:1581-1588.
    PubMed         Abstract available

  25. CUI X, Wang J, Wu B, Zhao Q, et al
    Interventions for Persons with Young-Onset Dementia and Their Families: A Scoping Review.
    J Alzheimers Dis. 2024;97:1519-1531.
    PubMed         Abstract available

  26. ARMSTRONG MJ, Barnes LL
    Under-Diagnosis of Dementia with Lewy Bodies in Individuals Racialized as Black: Hypotheses Regarding Potential Contributors.
    J Alzheimers Dis. 2024;97:1571-1580.
    PubMed         Abstract available

  27. GROECHEL RC, Liu AC, Koton S, Kucharska-Newton AM, et al
    Associations Between Mid-Life Psychosocial Measures and Estimated Late Life Amyloid Burden: The Atherosclerosis Risk in Communities (ARIC)-PET Study.
    J Alzheimers Dis. 2024;97:1901-1911.
    PubMed         Abstract available

  28. BACHAND AM, Dell LD
    Can Incorrect Analysis of Time-Dependent Exposure Explain Associations between PM2.5 Exposure and Risk of Dementia?
    J Alzheimers Dis. 2024;97:1931-1937.
    PubMed         Abstract available

  29. VERMEULEN RJ, Roudijk B, Govers TM, Rovers MM, et al
    Prognostic Information on Progression to Dementia: Quantification of the Impact on Quality of Life.
    J Alzheimers Dis. 2024;97:1829-1840.
    PubMed         Abstract available

  30. HARRIS JL, Wang X, Christian SK, Novikova L, et al
    Traumatic Brain Injury Alters the Trajectory of Age-Related Mitochondrial Change.
    J Alzheimers Dis. 2024;97:1793-1806.
    PubMed         Abstract available

  31. VALENCIA-OLVERA AC, Balu D, Moore A, Shah M, et al
    APOE2 Heterozygosity Reduces Hippocampal Soluble Amyloid-beta42 Levels in Non-Hyperlipidemic Mice.
    J Alzheimers Dis. 2024;97:1629-1639.
    PubMed         Abstract available

  32. ZHANG S, Ai H, Wang J, Liu T, et al
    Reduced Prefrontal-Thalamic Theta Flow During Working Memory Retrieval in APP/PS1 Mice.
    J Alzheimers Dis. 2024;97:1737-1749.
    PubMed         Abstract available

  33. DAI Y, Hsu YC, Fernandes BS, Zhang K, et al
    Disentangling Accelerated Cognitive Decline from the Normal Aging Process and Unraveling Its Genetic Components: A Neuroimaging-Based Deep Learning Approach.
    J Alzheimers Dis. 2024;97:1807-1827.
    PubMed         Abstract available

  34. HEIKKINEN AL, Paajanen TI, Hanninen T, Tikkanen V, et al
    Neuropsychological Profiles, Etiologies, and Medical Comorbidities in Early-Onset Dementia and Cognitive Impairment: A Memory Outpatient Clinic Cohort Study.
    J Alzheimers Dis. 2024;97:1765-1776.
    PubMed         Abstract available

  35. VESTIN E, Bostrom G, Olsson J, Elgh F, et al
    Herpes Simplex Viral Infection Doubles the Risk of Dementia in a Contemporary Cohort of Older Adults: A Prospective Study.
    J Alzheimers Dis. 2024;97:1841-1850.
    PubMed         Abstract available

    J Am Geriatr Soc

  36. RONCARATI JS, DeVone F, Halladay C, Tsai J, et al
    Risk of dementia among veterans experiencing homelessness and housing instability.
    J Am Geriatr Soc. 2024;72:382-389.
    PubMed         Abstract available

  37. HANSON LC, Wessell K, Meeks N, Bennett AV, et al
    Selecting outcomes for pragmatic clinical trials in dementia care: The IMPACT Collaboratory iLibrary.
    J Am Geriatr Soc. 2024;72:529-535.
    PubMed         Abstract available

    J Neurochem

  38. PEREIRA JD, Teixeira LCR, Mamede I, Alves MT, et al
    miRNAs in cerebrospinal fluid associated with Alzheimer's disease: A systematic review and pathway analysis using a data mining and machine learning approach.
    J Neurochem. 2024 Feb 23. doi: 10.1111/jnc.16060.
    PubMed         Abstract available

    Lipid imaging of Alzheimer's disease pathology.
    J Neurochem. 2024 Feb 19. doi: 10.1111/jnc.16079.
    PubMed         Abstract available

  40. ZHANG JF, Fang ZT, Zhao JN, Liu GP, et al
    Acetylated tau exacerbates apoptosis by disturbing mitochondrial dynamics in HEK293 cells.
    J Neurochem. 2024;168:288-302.
    PubMed         Abstract available

    J Neurosci

  41. MABOUDIAN SA, Willbrand EH, Jagust WJ, Weiner KS, et al
    Defining overlooked structures reveals new associations between cortex and cognition in aging and Alzheimer's disease.
    J Neurosci. 2024 Feb 21:e1714232024. doi: 10.1523/JNEUROSCI.1714-23.2024.
    PubMed         Abstract available

  42. ZHOU J, Wearn A, Huck J, Hughes C, et al
    Iron deposition and distribution across the hippocampus is associated with pattern separation and pattern completion in older adults at risk for Alzheimer's disease.
    J Neurosci. 2024 Feb 22:e1973232024. doi: 10.1523/JNEUROSCI.1973-23.2024.
    PubMed         Abstract available

    Lancet Neurol

    Dementia diagnosis in the anti-amyloid era.
    Lancet Neurol. 2024;23:219.

  44. FRISONI GB, Festari C, Massa F, Cotta Ramusino M, et al
    European intersocietal recommendations for the biomarker-based diagnosis of neurocognitive disorders.
    Lancet Neurol. 2024;23:302-312.
    PubMed         Abstract available

    N Engl J Med

  45. JIA J, Ning Y, Chen M, Wang S, et al
    Biomarker Changes during 20 Years Preceding Alzheimer's Disease.
    N Engl J Med. 2024;390:712-722.
    PubMed         Abstract available

  46. MAYEUX R
    Alzheimer's Disease Biomarkers - Timing Is Everything.
    N Engl J Med. 2024;390:761-763.

    Nat Med

  47. BARTHELEMY NR, Salvado G, Schindler S, He Y, et al
    Highly Accurate Blood Test for Alzheimer's Disease Comparable or Superior to Clinical CSF Tests.
    Nat Med. 2024 Feb 21. doi: 10.1038/s41591-024-02869.
    PubMed         Abstract available

    Nat Rev Neurol

  48. GOTZ J, Padmanabhan P
    Ultrasound and antibodies - a potentially powerful combination for Alzheimer disease therapy.
    Nat Rev Neurol. 2024 Feb 20. doi: 10.1038/s41582-024-00943.

    Nat Rev Neurosci

    Linking activity dyshomeostasis and sleep disturbances in Alzheimer disease.
    Nat Rev Neurosci. 2024 Feb 19. doi: 10.1038/s41583-024-00797.
    PubMed         Abstract available

    Neurobiol Aging

  50. SIMON SS, Varangis E, Lee S, Gu Y, et al
    In vivo tau is associated with change in memory and processing speed, but not reasoning, in cognitively unimpaired older adults.
    Neurobiol Aging. 2024;133:28-38.
    PubMed         Abstract available

  51. TWITTO-GREENBERG R, Liraz-Zaltsman S, Michaelson DM, Liraz O, et al
    9-cis beta-carotene-enriched diet significantly improved cognition and decreased Alzheimer's disease neuropathology and neuroinflammation in Alzheimer's disease-like mouse models.
    Neurobiol Aging. 2024;133:16-27.
    PubMed         Abstract available

    Neurochem Res

  52. XIAO X, Rui Y, Jin Y, Chen M, et al
    Relationship of Sleep Disorder with Neurodegenerative and Psychiatric Diseases: An Updated Review.
    Neurochem Res. 2024;49:568-582.
    PubMed         Abstract available


  53. FLEISHER AS, Munsie LM, Perahia DGS, Andersen SW, et al
    Assessment of Efficacy and Safety of Zagotenemab: Results From PERISCOPE-ALZ, a Phase 2 Study in Early Symptomatic Alzheimer Disease.
    Neurology. 2024;102:e208061.
    PubMed         Abstract available

  54. CHRISTENSEN GM, Li Z, Liang D, Ebelt S, et al
    Association of PM(2.5) Exposure and Alzheimer Disease Pathology in Brain Bank Donors-Effect Modification by APOE Genotype.
    Neurology. 2024;102:e209162.
    PubMed         Abstract available

  55. HONIG M, Altomare D, Caprioglio C, Collij L, et al
    Association Between Years of Education and Amyloid Burden in Patients With Subjective Cognitive Decline, MCI, and Alzheimer Disease.
    Neurology. 2024;102:e208053.
    PubMed         Abstract available

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