Home The Word Brain	My Amedeo FAQ Privacy About
	Explore this week’s CC Journal Club 90‑sec video • 4‑min audio • paper abstracts This week, 27 April 2025: Treatment-resistant hypertension Influenza transmission Nanoplastics in human brains Malaria elimination Chikungunya vaccine

Alzheimer's Disease

Free Subscription 17.03.2025 1 Am J Geriatr Psychiatry 2 Ann Neurol 1 Biochemistry 1 BMJ 10 J Alzheimers Dis 1 J Biol Chem 1 Lancet 1 Nat Med 1 Nat Neurosci 1 Neurobiol Aging 1 Neurobiol Dis 1 Neurochem Res 1 Neurology 2 Neuropsychology 2 Neurosci Lett 1 Neuroscience 1 PLoS One 1 Rev Neurol (Paris)

Retrieve available abstracts of this week’s articles: HTML format

Single Articles

Am J Geriatr Psychiatry

1. GONZALEZ DA, Finley JA, Patel SES, Soble JR, et al
   Practical Assessment of Neuropsychiatric Symptoms: Updated Reliability, Validity, and Cutoffs for the Neuropsychiatric Inventory Questionnaire.
   Am J Geriatr Psychiatry. 2025;33:524-534.
   PubMed         Abstract available
   
   

   
   Ann Neurol

2. ARRIOLA-INFANTE JE, Morcillo-Nieto AO, Zsadanyi SE, Franquesa-Mullerat M, et al
   Regional Brain Metabolism across the Alzheimer's Disease Continuum in Down Syndrome.
   Ann Neurol. 2025 Mar 14. doi: 10.1002/ana.27226.
   PubMed         Abstract available
   
   
3. AFFANEH A, Linden AK, Tunc-Ozcan E, Tsai YH, et al
   Inhibition of Bone Morphogenetic Protein Signaling Prevents Tau Pathology in iPSC Derived Neurons and PS19 Mice.
   Ann Neurol. 2025;97:657-672.
   PubMed         Abstract available
   
   

   
   Biochemistry

4. ANGEHRN FN, Duan P, Zhang JY, Hong M, et al
   Binding Sites of a PET Ligand in Tau Fibrils with the Alzheimer's Disease Fold from (19)F and (13)C Solid-State NMR.
   Biochemistry. 2025 Mar 11. doi: 10.1021/acs.biochem.5c00016.
   PubMed         Abstract available
   
   

   
   BMJ

5. MAHASE E
   Lecanemab and donanemab: NICE reconsiders controversial Alzheimer's drugs.
   BMJ. 2025;388:r463.
   PubMed        
   
   

   
   J Alzheimers Dis

6. ISHIKAWA-TAKATA K, Fujiwara K, Tanaka T, Nakamura K, et al
   Associations of dietary protein and amino acid intakes with disability-adjusted life years for Alzheimer's disease in Japanese people.
   J Alzheimers Dis. 2025 Mar 14:13872877251319535. doi: 10.1177/13872877251319535.
   PubMed         Abstract available
   
   
7. PIERCE ME, Logue M, Sherva R, Miller M, et al
   Association of Alzheimer's disease genetic risk with age-dependent changes in plasma amyloid-beta(42:40) in Veterans.
   J Alzheimers Dis. 2025 Mar 14:13872877251321183. doi: 10.1177/13872877251321183.
   PubMed         Abstract available
   
   
8. WANG D, Scalici A, Wang Y, Lin H, et al
   Frequency of variants in Mendelian Alzheimer's disease genes within the Alzheimer's Disease Sequencing Project.
   J Alzheimers Dis. 2025 Mar 14:13872877251320375. doi: 10.1177/13872877251320375.
   PubMed         Abstract available
   
   
9. KUMAR WS, Bhutare SR, Sinha N, Issac TG, et al
   Bayesian network modeling of statistical dependency within cognitive domains and clinical dementia severity ratings for Western and Indian cohorts.
   J Alzheimers Dis. 2025;104:221-231.
   PubMed         Abstract available
   
   
10. TREMBLAY C, Shakir N, Zhang N, Adler CH, et al
    Associations between neuropsychiatric symptoms and pathology in clinicopathologically defined Alzheimer's disease, Alzheimer's disease with Lewy bodies, and dementia with Lewy bodies.
    J Alzheimers Dis. 2025 Mar 14:13872877251320670. doi: 10.1177/13872877251320670.
    PubMed         Abstract available
    
    
11. ALVES L, Hashiguchi D, Loss CM, van Praag H, et al
    Vascular dysfunction in Alzheimer's disease: Exploring the potential of aerobic and resistance exercises as therapeutic strategies.
    J Alzheimers Dis. 2025 Mar 13:13872877251321118. doi: 10.1177/13872877251321118.
    PubMed         Abstract available
    
    
12. KIM JW, Byun MS, Yi D, Jung JH, et al
    Daily fluid intake and brain amyloid deposition: A cohort study.
    J Alzheimers Dis. 2025;104:138-149.
    PubMed         Abstract available
    
    
13. YANG Q, Yang H, Long W, Zuo S, et al
    Rapid cognitive assessment: Accuracy and discriminant validity of Mini-Cog and process-based Clock Drawing Test.
    J Alzheimers Dis. 2025;104:200-208.
    PubMed         Abstract available
    
    
14. SALMAN Y, Huyghe L, Quenon L, Ghysens O, et al
    Autopsy-proven patient with corticobasal degeneration presenting with visuo-constructive disorders as initial symptoms: How advanced MRI sequences can help clinical practice.
    J Alzheimers Dis. 2025;104:158-172.
    PubMed         Abstract available
    
    
15. PARK SA, An YS, Park YJ, Lee JY, et al
    Comparative analysis of Elecsys and ELISA for differentiating amyloid-PET status in a Korean memory clinic based on cerebrospinal fluid biomarkers.
    J Alzheimers Dis. 2025;104:232-244.
    PubMed         Abstract available
    
    

    
    J Biol Chem

16. RAHMAN MW, Sharma P, Chattopadhyay T, Saroja SR, et al
    Distinct neuronal vulnerability and metabolic dysfunctions are characteristic features of fast-progressing Alzheimer's patients with Lewy bodies.
    J Biol Chem. 2025 Mar 10:108396. doi: 10.1016/j.jbc.2025.108396.
    PubMed         Abstract available
    
    

    
    Lancet

17. ELIA-ZUDAIRE O, Tirado-Galindo M
    Towards a European imaging infrastructure for Alzheimer's disease.
    Lancet. 2025;405:779.
    PubMed        
    
    

    
    Nat Med

18. RASH BG, Ramdas KN, Agafonova N, Naioti E, et al
    Allogeneic mesenchymal stem cell therapy with laromestrocel in mild Alzheimer's disease: a randomized controlled phase 2a trial.
    Nat Med. 2025 Mar 10. doi: 10.1038/s41591-025-03559.
    PubMed         Abstract available
    
    

    
    Nat Neurosci

19. ZELENKA L
    SARS-CoV-2 affects Alzheimer's disease.
    Nat Neurosci. 2025;28:433.
    PubMed        
    
    

    
    Neurobiol Aging

20. ALBERTAZZI A, Murphy C
    Brain activation in older adults during odor identification is related to ApoE, t-tau/Abeta(1-42), and hippocampal volume.
    Neurobiol Aging. 2025;149:44-53.
    PubMed         Abstract available
    
    

    
    Neurobiol Dis

21. PINI L, Brusini L, Griffa A, Cruciani F, et al
    Functional dynamic network connectivity differentiates biological patterns in the Alzheimer's disease continuum.
    Neurobiol Dis. 2025 Mar 11:106866. doi: 10.1016/j.nbd.2025.106866.
    PubMed         Abstract available
    
    

    
    Neurochem Res

22. ORDONEZ WOC, Palomino NV, Varela PEV, Martinez IB, et al
    Alkaloids from Caliphruria subedentata (Amaryllidaceae) as Regulators of AChE, BuChE, NMDA and GSK3 Activity: An In Vitro and In Silico Approach for Mimicking Alzheimer s Disease.
    Neurochem Res. 2025;50:116.
    PubMed         Abstract available
    
    

    
    Neurology

23. SANCHEZ E, Coughlan GT, Wilkinson T, Ramirez J, et al
    Association of Plasma Biomarkers With Longitudinal Atrophy and Microvascular Burden on MRI Across Neurodegenerative and Cerebrovascular Diseases.
    Neurology. 2025;104:e213438.
    PubMed         Abstract available
    
    

    
    Neuropsychology

24. HABERMAS T, Gruler C, Jaeschke N, Rapp L, et al
    The temporal organization and quality of life story memories in Alzheimer disease and healthy controls.
    Neuropsychology. 2025;39:201-213.
    PubMed         Abstract available
    
    
25. GONZALEZ AI, Edwards LC, Thomas KR, Weigand AJ, et al
    Growth-associated protein 43 is associated with faster functional decline among amyloid-positive individuals with objectively defined subtle cognitive decline and mild cognitive impairment.
    Neuropsychology. 2025;39:248-258.
    PubMed         Abstract available
    
    

    
    Neurosci Lett

26. ZHANG C, Xu J, Xu F, Xie X, et al
    1-Epilupinine enhances cognition and reduces inflammation in scopolamine-induced dementia model mice.
    Neurosci Lett. 2025;852:138184.
    PubMed         Abstract available
    
    
27. TAHERI S, Paknejadi M, Esmaeili D, Ferdousi A, et al
    Studying the effect of Chlamydia trachomatis, Helicobacter pylori, and Varicella zoster microorganisms in stimulating the expression of cytokines TNFalpha, IFN?, TGFbeta, IL-10 in Alzheimer and non-Alzheimer patients.
    Neurosci Lett. 2025 Mar 9:138192. doi: 10.1016/j.neulet.2025.138192.
    PubMed         Abstract available
    
    

    
    Neuroscience

28. YAN X, Wang E, Zhao M, Ma G, et al
    Microbial infection instigates tau-related pathology in Alzheimer's disease via activating neuroimmune cGAS-STING pathway.
    Neuroscience. 2025;572:122-133.
    PubMed         Abstract available
    
    

    
    PLoS One

29. TAKOMTHONG P, Waiwut P, Yenjai C, Wangboonskul J, et al
    Kaempferia parviflora extract and its methoxyflavones as potential anti-Alzheimer assessing in vitro, integrated computational approach, and in vivo impact on behaviour in scopolamine-induced amnesic mice.
    PLoS One. 2025;20:e0316888.
    PubMed         Abstract available
    
    

    
    Rev Neurol (Paris)

30. LEROY M, Aziz AL, Schraen S, Deramecourt V, et al
    Comparing high and low amyloid producers in Alzheimer's disease: An in-depth analysis.
    Rev Neurol (Paris). 2025 Mar 7:S0035-3787(25)00432.
    PubMed         Abstract available
    
    

Thank you for your interest in scientific medicine.

AMEDEO Alzheimer's Disease is free of charge.