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  Alzheimer's Disease

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02.02.2026

14 Alzheimers Dement
2 Am J Alzheimers Dis Other Demen
2 Ann Neurol
1 BMC Geriatr
1 BMC Neurosci
1 Curr Alzheimer Res
1 Curr Opin Neurol
14 J Alzheimers Dis
1 J Neuropsychol
4 Lancet Neurol
1 Nat Ment Health
1 Nature
3 Neurology
3 Neuroscience


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Alzheimers Dement

  1. SHENG Z, Chen Y, Chen M, Liang S, et al
    Astrocyte-vascular interplay in Alzheimer's disease pathology: Novel insights into stage-specific biomarkers and therapeutic targets.
    Alzheimers Dement. 2026;22:e71122.
    PubMed         Abstract available

  2. CLAYTON WB, Kulas JA, Liu J, Walia N, et al
    Evaluation of ASC as a therapeutic target for Alzheimer's disease.
    Alzheimers Dement. 2026;22:e71104.
    PubMed         Abstract available

  3. HAMMERS DB, Eloyan A, Thangarajah M, Taurone A, et al
    Relationship between age and severity of cognitive impairment at diagnosis for early-onset and late-onset Alzheimer's disease: Comparison of LEADS and ADNI.
    Alzheimers Dement. 2026;22:e71160.
    PubMed         Abstract available

  4. PANG H, Frontera J, Jiang L, Li C, et al
    Choroid plexus alterations in long COVID and their associations with Alzheimer's disease risks.
    Alzheimers Dement. 2026;22:e71020.
    PubMed         Abstract available

  5. CHA WJ, Chumin EJ, Yi D, Byun MS, et al
    Amyloid-related default mode network hyperconnectivity and longitudinal decline in network distinctiveness in preclinical Alzheimer's disease.
    Alzheimers Dement. 2026;22:e71025.
    PubMed         Abstract available

  6. MURALI KP, Gills J, Turner A, Briggs A, et al
    Racial, ethnic and sex-specific mechanisms of obstructive sleep apnea and Alzheimer's disease risk.
    Alzheimers Dement. 2026;22:e71144.
    PubMed         Abstract available

  7. LIBBY JB, Deters KD, Ertekin-Taner N, Carrasquillo MM, et al
    Multi-omic expression of the VEGF family relates to Alzheimer's disease across diverse populations.
    Alzheimers Dement. 2026;22:e71100.
    PubMed         Abstract available

  8. MOHS RC, Beauregard DW, Hughes L, Cordell CB, et al
    Biomarkers in patients with clinical signs of mild cognitive impairment or mild Alzheimer's disease but without amyloid deposits on positron emission tomography: Results from Bio-Hermes Study participants.
    Alzheimers Dement. 2026;22:e71085.
    PubMed         Abstract available

  9. DONOHUE MC, Hussen K, Langford O, Gallardo R, et al
    Alzheimer's clinical research data via R packages: The alzverse.
    Alzheimers Dement. 2026;22:e71152.
    PubMed         Abstract available

  10. ENDURU N, Zhao Z
    PRISM-xQTL: Pleiotropic Relationships Integrated with System-level Multiomic QTL analysis for causal genes and molecular mediators in Alzheimer's disease.
    Alzheimers Dement. 2026;22:e71073.
    PubMed         Abstract available

  11. ZHANG YC, Zhang XT, Chen PY, Zhou ZY, et al
    Impaired adrenergic regulation of Kv channels underlies LC hyperactivity and early-onset sleep disruption in AD-like amyloidogenic mice.
    Alzheimers Dement. 2026;22:e71127.
    PubMed         Abstract available

  12. TANG C, Yang J, Lei X, Zhang M, et al
    Association between brain volume and depression in Alzheimer's disease: Neuroimaging insights.
    Alzheimers Dement. 2026;22:e71120.
    PubMed         Abstract available

  13. DAVEN M, Bass DM, Deaner N, Sawyer RJ, et al
    A framework for implementing high-quality dementia care navigation: recommendations from the Alzheimer's Association Dementia Care Navigation Roundtable.
    Alzheimers Dement. 2026;22:e71102.
    PubMed         Abstract available

  14. ZHENG W, Jiang Y, Wong HY, Wong WW, et al
    Targeted blood proteome profiling using NULISAseq identifies a high-performance biomarker panel for Abeta pathology quantification and staging.
    Alzheimers Dement. 2026;22:e71179.
    PubMed         Abstract available


    Am J Alzheimers Dis Other Demen

  15. ZHU Z, Zhang X, Xu C, Shen Y, et al
    Construction and Interpretability of a Multimodal Deep Learning Model of Electronystagmography-Optical Coherence Tomography Angiography for Early Screening of Alzheimer's Disease.
    Am J Alzheimers Dis Other Demen. 2026;41:15333175261422037.
    PubMed         Abstract available

  16. HUR M, Kim M, Min S, Lee CH, et al
    Cognitive and Mental Health Differences Across Latent Profiles of Religiosity and Spirituality in Korean Older Adults With Mild Cognitive Impairment or Alzheimer's Disease.
    Am J Alzheimers Dis Other Demen. 2026;41:15333175251415119.
    PubMed         Abstract available


    Ann Neurol

  17. MABOUDIAN SA, Fonseca CS, Martersteck AC, Chao Y, et al
    Tau Pathology in Alzheimer's Disease Uniquely Affects Sulcal Depths.
    Ann Neurol. 2026 Jan 24. doi: 10.1002/ana.78166.
    PubMed         Abstract available

  18. CANOVAS R, Cox T, Dore V, Bourgeat P, et al
    When Does Alzheimer's Disease Start? Plasma Abeta42/40 Assays Show Steep Changes at Abeta-PET Centiloid 15, Mean Age of 66 Years.
    Ann Neurol. 2026 Jan 26. doi: 10.1002/ana.78163.
    PubMed         Abstract available


    BMC Geriatr

  19. KIANFAR N, Alsharayri S, Mollalo A
    Alzheimer's disease and related dementias in rural medicare populations: a scoping review.
    BMC Geriatr. 2026 Jan 27. doi: 10.1186/s12877-026-07031.
    PubMed         Abstract available


    BMC Neurosci

  20. YU L, Zhao M, Zhang W, Lv Z, et al
    Precise Abeta clearance and antioxidant therapy in Alzheimer's disease via photoacoustic imaging-guided palladium hydride nanosheet-mediated photothermal treatment.
    BMC Neurosci. 2026 Jan 29. doi: 10.1186/s12868-025-00994.
    PubMed        


    Curr Alzheimer Res

  21. SAHU A, Khileshwari, Patle K, Jain P, et al
    Advances in Nose-to-Brain Delivery Systems for Effective Alzheimer's Disease Management.
    Curr Alzheimer Res. 2026 Jan 21. doi: 10.2174/0115672050395356251106100427.
    PubMed         Abstract available


    Curr Opin Neurol

  22. JACOBS HIL
    The monoaminergic systems as drivers of Alzheimer's disease pathophysiology and symptomatology.
    Curr Opin Neurol. 2026 Jan 23. doi: 10.1097/WCO.0000000000001455.
    PubMed         Abstract available


    J Alzheimers Dis

  23. VINIKOOR-IMLER L, Yue EX, Boroje I, Sanchez-Solino O, et al
    Comorbidities associated with mild cognitive impairment and Alzheimer's disease in the United States.
    J Alzheimers Dis. 2026 Jan 27:13872877251411451. doi: 10.1177/13872877251411451.
    PubMed         Abstract available

  24. ZHANG L, Hu J, Zhang T, Gao H, et al
    The role of HDAC6-mediated Prx2 acetylation in neuronal apoptosis related to Alzheimer's disease.
    J Alzheimers Dis. 2026 Jan 27:13872877251414961. doi: 10.1177/13872877251414961.
    PubMed         Abstract available

  25. LI J, Yue H, Lian T, Qi J, et al
    The roles of helicobacter pylori infection on the pathogenesis of Alzheimer's disease: Gut-brain axis dysfunction and blood-brain barrier disruption.
    J Alzheimers Dis. 2026 Jan 27:13872877251412234. doi: 10.1177/13872877251412234.
    PubMed         Abstract available

  26. FULOP T, Cohen AA, Frost EH, Levesque S, et al
    Unmasking the hidden catalyst: How infections trigger Alzheimer's disease.
    J Alzheimers Dis. 2026 Jan 27:13872877251415571. doi: 10.1177/13872877251415571.
    PubMed         Abstract available

  27. PREVOT E, Shand C, Oxtoby N
    How reproducible are data-driven subtypes of Alzheimer's disease atrophy?
    J Alzheimers Dis. 2026 Jan 28:13872877251415019. doi: 10.1177/13872877251415019.
    PubMed         Abstract available

  28. SHA L, Wu M, Sun S, Xie Y, et al
    Subcutaneous transplantation of mesenchymal stem cell spheroids ameliorates cognitive deficits in Alzheimer's disease.
    J Alzheimers Dis. 2026 Jan 28:13872877261418164. doi: 10.1177/13872877261418164.
    PubMed         Abstract available

  29. WANG S, Wang C, Hong H, Tang C, et al
    An integrative multi-omics study reveals glutamine metabolism dysregulation connecting Alzheimer's disease and age-related macular degeneration.
    J Alzheimers Dis. 2026 Jan 28:13872877261418263. doi: 10.1177/13872877261418263.
    PubMed         Abstract available

  30. DAS G, Raghunathan R, Wang L, Wan Z, et al
    Retinal Muller glia alterations and their impact on ocular glymphatic clearance in an Alzheimer's disease mouse model.
    J Alzheimers Dis. 2026 Jan 28:13872877261418165. doi: 10.1177/13872877261418165.
    PubMed         Abstract available

  31. HO BL, Liu CF, Huang YB, Huang LC, et al
    Treatment persistence with acetylcholinesterase inhibitors in Alzheimer's disease: Real-world evidence from a retrospective cohort study.
    J Alzheimers Dis. 2026 Jan 28:13872877251415021. doi: 10.1177/13872877251415021.
    PubMed         Abstract available

  32. SHINAGAWA S, Nagata T, Noto S, Yamato K, et al
    Caregiver burden and quality of life associated with behavioral and psychological symptoms of Alzheimer's disease: A web-based cross-sectional survey study.
    J Alzheimers Dis. 2026 Jan 28:13872877261415637. doi: 10.1177/13872877261415637.
    PubMed         Abstract available

  33. BYEON JH, Lee D, Shin EJ, Park EM, et al
    Validation of a web-based cognitive test for early detection of Alzheimer's disease.
    J Alzheimers Dis. 2026 Jan 28:13872877261415925. doi: 10.1177/13872877261415925.
    PubMed         Abstract available

  34. TIWARI P, Gupta A, Kaushik M, Dwivedi R, et al
    Association of yoga with cognitive and gut microbiome changes in Alzheimer's disease: An exploratory case-control study.
    J Alzheimers Dis. 2026 Jan 28:13872877261415612. doi: 10.1177/13872877261415612.
    PubMed         Abstract available

  35. XU C, Zhang K, Shi W, Mubarik S, et al
    Analysis of trends and driving factors in burden of Alzheimer's disease and other dementias from 1990 to 2021 and projections for 2050: A comprehensive perspective based on GBD 2021.
    J Alzheimers Dis. 2026 Jan 28:13872877261415634. doi: 10.1177/13872877261415634.
    PubMed         Abstract available

  36. SCOLLARD P, Mukherjee S, Choi SE, Lee ML, et al
    Heterogeneous patterns of cognitive decline in Alzheimer's disease across three domains of cognition.
    J Alzheimers Dis. 2026 Jan 28:13872877251414975. doi: 10.1177/13872877251414975.
    PubMed         Abstract available


    J Neuropsychol

  37. MAUSSIRE C, El Haj M, Emmelin E, Besnard J, et al
    Introducing ISPA-AD: Interactive social problem-solving assessment for Alzheimer's disease.
    J Neuropsychol. 2026 Jan 28. doi: 10.1111/jnp.70030.
    PubMed         Abstract available


    Lancet Neurol

  38. VOSSEL K, Johnson EL, Cretin B, Matsumoto R, et al
    Epileptic activity in Alzheimer's disease: emerging insights and therapeutic implications.
    Lancet Neurol. 2026 Jan 22:S1474-4422(25)00425.
    PubMed         Abstract available

  39. DEVINSKY O
    Alzheimer's disease and epileptic activity: uncertainties abound.
    Lancet Neurol. 2026 Jan 22:S1474-4422(25)00496.
    PubMed        

  40. TARIOT PN, Lopera FS, Rios-Romenets S, Sink KM, et al
    Safety and efficacy of crenezumab in cognitively unimpaired carriers of the PSEN1(Glu280Ala) mutation at risk for autosomal-dominant Alzheimer's disease in Colombia (API ADAD Colombia Trial): a phase 2, randomised, double-blind, placebo-controlled tri
    Lancet Neurol. 2026;25:147-159.
    PubMed         Abstract available

  41. FORTEA J, Llibre-Guerra J, O'Connor A, Levin J, et al
    Lessons from the Colombian kindred: rethinking Alzheimer's prevention.
    Lancet Neurol. 2026;25:117-119.
    PubMed        


    Nat Ment Health

  42. KAPOOR A, Mather M, Nation DA
    Emotional enhancement of memory in Alzheimer's disease dementia: a systematic review.
    Nat Ment Health. 2025;3:1078-1087.
    PubMed         Abstract available


    Nature

  43. GRAHAM F
    Daily briefing: Why cancer might protect against Alzheimer's disease.
    Nature. 2026 Jan 23. doi: 10.1038/d41586-026-00257.
    PubMed        


    Neurology

  44. RANI N, Moghekar A, Callow DD, Alm KH, et al
    Association Between Longitudinal Rate of Change in CSF Biomarkers and Subsequent Tau PET Burden in Early Braak Stages.
    Neurology. 2026;106:e214620.
    PubMed         Abstract available

  45. IRWIN DJ
    Blood-Based Biomarkers and the Complexity of Neuropathologic Substrates of Alzheimer Disease and Related Disorders.
    Neurology. 2026;106:e214504.
    PubMed        

  46. KIVISAKK P, Fatima H, Wu CY, Padmanabhan N, et al
    Postmortem Associations Between Alzheimer Disease Pathology and Plasma pTau217, GFAP, and NfL in AD and AD-Related Dementias.
    Neurology. 2026;106:e214351.
    PubMed         Abstract available


    Neuroscience

  47. ZHANG N, Wang S, Gui Y, Li D, et al
    TLR2 regulation of NF-kappaB and NLRP3-driven pyroptosis in Alzheimer's disease.
    Neuroscience. 2026 Jan 23:S0306-4522(26)00063.
    PubMed         Abstract available

  48. ZHOU L, Wang Z, Jiang Y, Wang M, et al
    A Mendelian randomization study with bioinformatics analysis reveals gut microbiota mediates in heart failure and Alzheimer's disease via BAFF-R.
    Neuroscience. 2026 Jan 22:S0306-4522(26)00046.
    PubMed         Abstract available

  49. RIQUELME-CONTRERAS P, Henriquez F, Gonzalez-Campo C, Altschuler F, et al
    Impact of cardiometabolic factors and AD plasma biomarkers on white matter hyperintensities volume in individuals with cognitive complaints from the global south.
    Neuroscience. 2026;595:270-279.
    PubMed         Abstract available


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