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COVID-19: Daily Top 10 Papers

  Alzheimer's Disease

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4 Brain
1 Curr Alzheimer Res
37 J Alzheimers Dis
1 J Am Geriatr Soc
1 J Clin Psychiatry
1 J Neurochem
1 Nat Neurosci
1 Nat Rev Neurol
1 Nat Rev Neurosci
7 Neurobiol Aging
1 Neurobiol Dis
2 Neurol Genet
3 Neurology
1 Neuropsychology
1 Neurosci Lett
2 PLoS One
1 Rev Neurol (Paris)

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  1. STOTHART G, Smith LJ, Milton A, Coulthard E, et al
    A passive and objective measure of recognition memory in Alzheimer's disease using Fastball memory assessment.
    Brain. 2021 Sep 20. pii: 6372384. doi: 10.1093.
    PubMed         Abstract available

  2. Erratum to: Cardiovascular brain impulses in Alzheimer's disease.
    Brain. 2021 Sep 22. pii: 6373794. doi: 10.1093.

  3. RIES M, Watts H, Mota BC, Lopez MY, et al
    Annexin A1 restores cerebrovascular integrity concomitant with reduced amyloid-beta and tau pathology.
    Brain. 2021;144:1526-1541.
    PubMed         Abstract available

  4. BOYLE PA, Wang T, Yu L, Wilson RS, et al
    To what degree is late life cognitive decline driven by age-related neuropathologies?
    Brain. 2021;144:2166-2175.
    PubMed         Abstract available

    Curr Alzheimer Res

  5. LEKO MB, Perkovic MN, Erjavec GN, Klepac N, et al
    Association of the MAOB rs1799836 Single Nucleotide Polymorphism and APOE varepsilon4 Allele in Alzheimer's Disease.
    Curr Alzheimer Res. 2021 Sep 17. pii: CAR-EPUB-118026.
    PubMed         Abstract available

    J Alzheimers Dis

  6. SHINOHARA M, Suzuki K, Bu G, Sato N, et al
    Interaction Between APOE Genotype and Diabetes in Longevity.
    J Alzheimers Dis. 2021;82:719-726.
    PubMed         Abstract available

  7. KORPIOJA A, Kruger J, Koivuluoma S, Pylkas K, et al
    Novel Rare SORL1 Variants in Early-Onset Dementia.
    J Alzheimers Dis. 2021;82:761-770.
    PubMed         Abstract available

  8. SVENSSON J, Blomqvist M, Kettunen P, Eckerstrom C, et al
    Cerebrospinal Fluid Sulfatide Levels Lack Diagnostic Utility in the Subcortical Small Vessel Type of Dementia.
    J Alzheimers Dis. 2021;82:781-790.
    PubMed         Abstract available

  9. NIU J, Iqbal K, Liu F, Hu W, et al
    Rats Display Sexual Dimorphism in Phosphorylation of Brain Tau with Age.
    J Alzheimers Dis. 2021;82:855-869.
    PubMed         Abstract available

  10. ZILLI EM, O'Donnell A, Salinas J, Aparicio HJ, et al
    Herpes Labialis, Chlamydophila pneumoniae, Helicobacter pylori, and Cytomegalovirus Infections and Risk of Dementia: The Framingham Heart Study.
    J Alzheimers Dis. 2021;82:593-605.
    PubMed         Abstract available

  11. YERSTEIN O, Parand L, Liang LJ, Isaac A, et al
    Benson's Disease or Posterior Cortical Atrophy, Revisited.
    J Alzheimers Dis. 2021;82:493-502.
    PubMed         Abstract available

  12. KARANTH SD, Schmitt FA, Nelson PT, Katsumata Y, et al
    Four Common Late-Life Cognitive Trajectories Patterns Associate with Replicable Underlying Neuropathologies.
    J Alzheimers Dis. 2021;82:647-659.
    PubMed         Abstract available

  13. BEISHON LC, Panerai RB, Budgeon C, Subramaniam H, et al
    The Cognition and Flow Study: A Feasibility Randomized Controlled Trial of the Effects of Cognitive Training on Cerebral Blood Flow.
    J Alzheimers Dis. 2021;80:1567-1581.
    PubMed         Abstract available

  14. PAIS M, Loureiro J, do Vale V, Radanovic M, et al
    Heterogeneity of Cerebrospinal Fluid Biomarkers Profiles in Individuals with Distinct Levels of Cognitive Decline: A Cross-Sectional Study.
    J Alzheimers Dis. 2021;81:949-962.
    PubMed         Abstract available

  15. SIMONSEN AH, Musaeus CS, Christensen GL, Hasselbalch SG, et al
    Upwards Drift of Cerebrospinal Fluid Amyloid-beta 42 Over Twelve Years in a Consecutive Clinical Cohort.
    J Alzheimers Dis. 2021;81:1369-1373.
    PubMed         Abstract available

  16. WANG YY, Ge YJ, Tan CC, Cao XP, et al
    The Proportion of APOE4 Carriers Among Non-Demented Individuals: A Pooled Analysis of 389,000 Community-Dwellers.
    J Alzheimers Dis. 2021;81:1331-1339.
    PubMed         Abstract available

  17. ZHANG H, D'Agostino C, Forman HJ, Cacciottolo M, et al
    Urban Air Pollution Nanoparticles from Los Angeles: Recently Decreased Neurotoxicity.
    J Alzheimers Dis. 2021;82:307-316.
    PubMed         Abstract available

  18. ALMKVIST O, Bruggen K, Nordberg A
    Subcortical and Cortical Regions of Amyloid-beta Pathology Measured by 11C-PiB PET Are Differentially Associated with Cognitive Functions and Stages of Disease in Memory Clinic Patients.
    J Alzheimers Dis. 2021;81:1613-1624.
    PubMed         Abstract available

  19. NG KP, Cheng GH, Yatawara C, Rosa-Neto P, et al
    Baseline Neurodegeneration Influences the Longitudinal Effects of Tau on Cognition.
    J Alzheimers Dis. 2021;82:159-167.
    PubMed         Abstract available

  20. WOODWORTH DC, Scambray KA, Corrada MM, Kawas CH, et al
    Neuroimaging in the Oldest-Old: A Review of the Literature.
    J Alzheimers Dis. 2021;82:129-147.
    PubMed         Abstract available

  21. SHENG C, Lin L, Lin H, Wang X, et al
    Altered Gut Microbiota in Adults with Subjective Cognitive Decline: The SILCODE Study.
    J Alzheimers Dis. 2021;82:513-526.
    PubMed         Abstract available

  22. CHAPARRO D, Flores-Gaspar A, Ali-Torres J
    Computational Design of Copper Ligands with Controlled Metal Chelating, Pharmacokinetics, and Redox Properties for Alzheimer's Disease.
    J Alzheimers Dis. 2021;82.
    PubMed         Abstract available

  23. RIEGEROVA P, Brejcha J, Bezdekova D, Chum T, et al
    Expression and Localization of AbetaPP in SH-SY5Y Cells Depends on Differentiation State.
    J Alzheimers Dis. 2021;82:485-491.
    PubMed         Abstract available

  24. ABDULKADIR TS, Dawud FA, Isa AS, Ayo JO, et al
    Taurine and Camel Milk Modulate Neurobehavioral and Biochemical Changes in Aluminum Chloride-Induced Alzheimer's Disease in Rats.
    J Alzheimers Dis. 2021 Sep 10. pii: JAD210130. doi: 10.3233/JAD-210130.
    PubMed         Abstract available

  25. ALLEN HB
    A Novel Approach to the Treatment and Prevention of Alzheimer's Disease Based on the Pathology and Microbiology.
    J Alzheimers Dis. 2021 Sep 14. pii: JAD210429. doi: 10.3233/JAD-210429.
    PubMed         Abstract available

  26. CIANFLONE A, Coppola L, Mirabelli P, Salvatore M, et al
    Predictive Accuracy of Blood-Derived Biomarkers for Amyloid-beta Brain Deposition Along with the Alzheimer's Disease Continuum: A Systematic Review.
    J Alzheimers Dis. 2021 Sep 17. pii: JAD210496. doi: 10.3233/JAD-210496.
    PubMed         Abstract available

  27. BALEA-FERNANDEZ FJ, Martinez-Vega B, Ortega S, Fabelo H, et al
    Analysis of Risk Factors in Dementia Through Machine Learning.
    J Alzheimers Dis. 2021;79:845-861.
    PubMed         Abstract available

  28. BASTA M, Zaganas I, Simos P, Koutentaki E, et al
    Apolipoprotein E varepsilon4 (APOE varepsilon4) Allele is Associated with Long Sleep Duration Among Elderly with Cognitive Impairment.
    J Alzheimers Dis. 2021;79:763-771.
    PubMed         Abstract available

  29. KUMON H, Yoshino Y, Funahashi Y, Mori H, et al
    PICALM mRNA Expression in the Blood of Patients with Neurodegenerative Diseases and Geriatric Depression.
    J Alzheimers Dis. 2021;79:1055-1062.
    PubMed         Abstract available

  30. GRUTERS AAA, Ramakers IHGB, Stiekema APM, Verhey FRJ, et al
    An Exploratory Study of the Development and Pilot Testing of an Interactive Visual Tool of Neuropsychological Test Results in Memory Clinics.
    J Alzheimers Dis. 2021;79:1157-1170.
    PubMed         Abstract available

  31. XIAO T, Wijnant SRA, Licher S, Terzikhan N, et al
    Lung Function Impairment and the Risk of Incident Dementia: The Rotterdam Study.
    J Alzheimers Dis. 2021;82:621-630.
    PubMed         Abstract available

  32. GJORA L, Strand BH, Bergh S, Borza T, et al
    Current and Future Prevalence Estimates of Mild Cognitive Impairment, Dementia, and Its Subtypes in a Population-Based Sample of People 70 Years and Older in Norway: The HUNT Study.
    J Alzheimers Dis. 2021;79:1213-1226.
    PubMed         Abstract available

  33. DODICH A, Crespi C, Chiara Santi G, Luzzi S, et al
    Diagnostic Accuracy of Affective Social Tasks in the Clinical Classification Between the Behavioral Variant of Frontotemporal Dementia and Other Neurodegenerative Disease.
    J Alzheimers Dis. 2021 Mar 5. pii: JAD201210. doi: 10.3233/JAD-201210.
    PubMed         Abstract available

  34. CLARK AL, Weigand AJ, Thomas KR, Solders SK, et al
    Elevated Inflammatory Markers and Arterial Stiffening Exacerbate Tau but Not Amyloid Pathology in Older Adults with Mild Cognitive Impairment.
    J Alzheimers Dis. 2021;80:1451-1463.
    PubMed         Abstract available

  35. JARDEL A, Hopes L, Malaplate C, Roch V, et al
    Prognostic Impact of 18-F-Florbetaben Amyloid PET Imaging in Patients with Isolated Increases in Cerebrospinal Fluid Phospho-Tau Biomarkers: A Longitudinal Study.
    J Alzheimers Dis. 2021;80:1389-1394.
    PubMed         Abstract available

  36. YAMADA Y, Shinkawa K, Kobayashi M, Caggiano V, et al
    Combining Multimodal Behavioral Data of Gait, Speech, and Drawing for Classification of Alzheimer's Disease and Mild Cognitive Impairment.
    J Alzheimers Dis. 2021 Sep 16. pii: JAD210684. doi: 10.3233/JAD-210684.
    PubMed         Abstract available

  37. SATO T, Hanyu H, Koyama Y, Horita H, et al
    Discrepancy Between the Degree of Cognitive Impairment and Brain Imaging Abnormalities in Alzheimer's Disease Patients Is Associated with Cognitive Reserve.
    J Alzheimers Dis. 2021 Sep 10. pii: JAD210728. doi: 10.3233/JAD-210728.
    PubMed         Abstract available

  38. KOLINKO Y, Marsalova L, Pena SP, Kralickova M, et al
    Stereological Changes in Microvascular Parameters in Hippocampus of a Transgenic Rat Model of Alzheimer's Disease.
    J Alzheimers Dis. 2021 Sep 10. pii: JAD210738. doi: 10.3233/JAD-210738.
    PubMed         Abstract available

  39. LUKKARINEN H, Tesseur I, Pemberton D, Van Der Ark P, et al
    Time Trends of Cerebrospinal Fluid Biomarkers of Neurodegeneration in Idiopathic Normal Pressure Hydrocephalus.
    J Alzheimers Dis. 2021;80:1629-1642.
    PubMed         Abstract available

  40. TANNER JJ, Hanchate S, Price CC, Garvan C, et al
    Relationships Between Chronic Pain Stage, Cognition, Temporal Lobe Cortex, and Sociodemographic Variables.
    J Alzheimers Dis. 2021;80:1539-1551.
    PubMed         Abstract available

  41. DING XL, Tuo QZ, Lei P
    An Introduction to Ultrasensitive Assays for Plasma Tau Detection.
    J Alzheimers Dis. 2021;80:1353-1362.
    PubMed         Abstract available

  42. OVIEDO DC, Perez-Lao AR, Flores-Cuadra JA, Villarreal AE, et al
    Apolipoprotein varepsilon4 Affects Multiple Domains of Neuropsychological Functioning in a Sample of Elderly Hispanics.
    J Alzheimers Dis. 2021;82.
    PubMed         Abstract available

    J Am Geriatr Soc

  43. BARDENHEIER BH, Rahman M, Kosar C, Werner RM, et al
    Successful Discharge to Community Gap of FFS Medicare Beneficiaries With and Without ADRD Narrowed.
    J Am Geriatr Soc. 2021;69:972-978.
    PubMed         Abstract available

    J Clin Psychiatry

  44. ZANG F, Zhu Y, Liu X, Fan D, et al
    Polygenic Effects of the Lipid Metabolic Pathway Accelerated Pathological Changes and Disrupted Default Mode Network Trajectory Across the Alzheimer's Disease Spectrum.
    J Clin Psychiatry. 2021;82.
    PubMed         Abstract available

    J Neurochem

  45. JAKARIA M, Belaidi AA, Bush AI, Ayton S, et al
    Ferroptosis as a mechanism of neurodegeneration in Alzheimer's disease.
    J Neurochem. 2021 Sep 23. doi: 10.1111/jnc.15519.
    PubMed         Abstract available

    Nat Neurosci

  46. YANG C, Farias FHG, Ibanez L, Suhy A, et al
    Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders.
    Nat Neurosci. 2021;24:1302-1312.
    PubMed         Abstract available

    Nat Rev Neurol

  47. MCDADE E, Voytyuk I, Aisen P, Bateman RJ, et al
    The case for low-level BACE1 inhibition for the prevention of Alzheimer disease.
    Nat Rev Neurol. 2021 Sep 21. pii: 10.1038/s41582-021-00545.
    PubMed         Abstract available

    Nat Rev Neurosci

  48. OTTO G
    Myelin loss in AD.
    Nat Rev Neurosci. 2021;22:456-457.

    Neurobiol Aging

  49. YEUNG LK, Hale C, Rizvi B, Igwe K, et al
    Anterolateral entorhinal cortex volume is associated with memory retention in clinically unimpaired older adults.
    Neurobiol Aging. 2021;98:134-145.
    PubMed         Abstract available

  50. MUSCAT SM, Deems NP, D'Angelo H, Kitt MM, et al
    Postoperative cognitive dysfunction is made persistent with morphine treatment in aged rats.
    Neurobiol Aging. 2021;98:214-224.
    PubMed         Abstract available

  51. ZHANG Z, Wang M, Liu X
    C-reactive protein and risk of Alzheimer's disease.
    Neurobiol Aging. 2021 Aug 21. pii: S0197-4580(21)00264.
    PubMed         Abstract available

  52. LOW A, Su L, Stefaniak JD, Mak E, et al
    Inherited risk of dementia and the progression of cerebral small vessel disease and inflammatory markers in cognitively healthy midlife adults: the PREVENT-Dementia study.
    Neurobiol Aging. 2021;98:124-133.
    PubMed         Abstract available

  53. MEEKER KL, Ances BM, Gordon BA, Rudolph CW, et al
    Cerebrospinal fluid Abeta42 moderates the relationship between brain functional network dynamics and cognitive intraindividual variability.
    Neurobiol Aging. 2021;98:116-123.
    PubMed         Abstract available

  54. WILLEMSE EAJ, Sieben A, Somers C, Vermeiren Y, et al
    Neurogranin as biomarker in CSF is non-specific to Alzheimer's disease dementia.
    Neurobiol Aging. 2021;108:99-109.
    PubMed         Abstract available

  55. WHITWELL JL, Tosakulwong N, Weigand SD, Graff-Radford J, et al
    Relationship of APOE, age at onset, amyloid and clinical phenotype in Alzheimer disease.
    Neurobiol Aging. 2021;108:90-98.
    PubMed         Abstract available

    Neurobiol Dis

  56. OCHIAI T, Sano T, Nagayama T, Kubota N, et al
    Differential involvement of insulin receptor substrate (IRS)-1 and IRS-2 in brain insulin signaling is associated with the effects on amyloid pathology in a mouse model of Alzheimer's disease.
    Neurobiol Dis. 2021 Sep 16:105510. doi: 10.1016/j.nbd.2021.105510.
    PubMed         Abstract available

    Neurol Genet

  57. GERRING ZF, Gamazon ER, White A, Derks EM, et al
    Integrative Network-Based Analysis Reveals Gene Networks and Novel Drug Repositioning Candidates for Alzheimer Disease.
    Neurol Genet. 2021;7:e622.
    PubMed         Abstract available

  58. GRANGEON L, Cassinari K, Rousseau S, Croisile B, et al
    Early-Onset Cerebral Amyloid Angiopathy and Alzheimer Disease Related to an APP Locus Triplication.
    Neurol Genet. 2021;7:e609.
    PubMed         Abstract available


  59. MILA-ALOMA M, Brinkmalm A, Ashton NJ, Kvartsberg H, et al
    CSF Synaptic Biomarkers in the Preclinical Stage of Alzheimer Disease and Their Association With MRI and PET: A Cross-sectional Study.
    Neurology. 2021 Sep 23. pii: WNL.0000000000012853.
    PubMed         Abstract available

  60. JUTTEN RJ, Sikkes SAM, Van der Flier WM, Scheltens P, et al
    Finding Treatment Effects in Alzheimer Trials in the Face of Disease Progression Heterogeneity.
    Neurology. 2021;96:e2673-e2684.
    PubMed         Abstract available

  61. BUCKLEY RF, Knopman DS
    Cognitive Heterogeneity in Alzheimer Clinical Trials: Harnessing Noise to Achieve Meaningfulness.
    Neurology. 2021;96:1017-1018.


  62. MONTEMURRO S, Mondini S, Arcara G
    Heterogeneity of effects of cognitive reserve on performance in probable Alzheimer's disease and in subjective cognitive decline.
    Neuropsychology. 2021 Sep 23. pii: 2021-86668-001. doi: 10.1037/neu0000770.
    PubMed         Abstract available

    Neurosci Lett

  63. GAO F, Liu T, Tuo M, Chi S, et al
    The role of orexin in Alzheimer disease: From sleep-wake disturbance to therapeutic target.
    Neurosci Lett. 2021;765:136247.
    PubMed         Abstract available

    PLoS One

  64. PIERSSON AD, Ibrahim B, Suppiah S, Mohamad M, et al
    Multiparametric MRI for the improved diagnostic accuracy of Alzheimer's disease and mild cognitive impairment: Research protocol of a case-control study design.
    PLoS One. 2021;16:e0252883.
    PubMed         Abstract available

  65. WICKLAND DP, Ren Y, Sinnwell JP, Reddy JS, et al
    Impact of variant-level batch effects on identification of genetic risk factors in large sequencing studies.
    PLoS One. 2021;16:e0249305.
    PubMed         Abstract available

    Rev Neurol (Paris)

  66. FATHI M, Taghizadeh F, Mojtahedi H, Zargar Balaye Jame S, et al
    The effects of Alzheimer's and Parkinson's disease on 28-day mortality of COVID-19.
    Rev Neurol (Paris). 2021 Sep 13. pii: S0035-3787(21)00653.
    PubMed         Abstract available

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