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  Alzheimer's Disease

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04.03.2024

1 Acta Neuropathol
3 Alzheimer Dis Assoc Disord
7 Alzheimers Dement
5 Ann Neurol
1 BMC Neurol
2 Brain Res
4 Curr Alzheimer Res
1 Exp Gerontol
26 J Alzheimers Dis
1 J Neurol
1 J Neurosci
2 N Engl J Med
1 Nat Rev Neurol
4 Neurobiol Aging
2 Neurobiol Dis
1 Neurology
1 Neuroscience
1 Proc Natl Acad Sci U S A


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Acta Neuropathol

  1. ALEXANDER A, Alvarez VE, Huber BR, Alosco ML, et al
    Cortical-sparing chronic traumatic encephalopathy (CSCTE): a distinct subtype of CTE.
    Acta Neuropathol. 2024;147:45.
    PubMed         Abstract available


    Alzheimer Dis Assoc Disord

  2. SEWELL M, Neugroschl J, Zhu CW, Loizos M, et al
    Lessons From the Coronavirus Disease Experience: Research Participant and Staff Satisfaction With Remote Cognitive Evaluations.
    Alzheimer Dis Assoc Disord. 2024;38:65-69.
    PubMed         Abstract available

  3. SABBAGH MN, Michalak W, Thim Hansen C, Ahmad Wichmann C, et al
    Rescreening on RBANS Delayed Memory Index? Forget About It!
    Alzheimer Dis Assoc Disord. 2024;38:8-13.
    PubMed         Abstract available

  4. STITES SD, Lee BN, Rubright JD, Harkins K, et al
    Cognitive Complaint Types Can Correlate With Cognitive Testing, Perceived Stress, and Symptom Distress in Older Adults With Normal Cognition and Dementia.
    Alzheimer Dis Assoc Disord. 2024;38:34-41.
    PubMed         Abstract available


    Alzheimers Dement

  5. SONI N, Hohsfield LA, Tran KM, Kawauchi S, et al
    Genetic diversity promotes resilience in a mouse model of Alzheimer's disease.
    Alzheimers Dement. 2024 Mar 1. doi: 10.1002/alz.13753.
    PubMed         Abstract available

  6. RUTHIRAKUHAN M, Swardfager W, Xiong L, MacIntosh BJ, et al
    Investigating the impact of hypertension with and without diabetes on Alzheimer's disease risk: A clinico-pathological study.
    Alzheimers Dement. 2024 Feb 29. doi: 10.1002/alz.13717.
    PubMed         Abstract available

  7. NEWTON C, Pope M, Rua C, Henson R, et al
    Entorhinal-based path integration selectively predicts midlife risk of Alzheimer's disease.
    Alzheimers Dement. 2024 Feb 29. doi: 10.1002/alz.13733.
    PubMed         Abstract available

  8. MOHS RC, Beauregard D, Dwyer J, Gaudioso J, et al
    The Bio-Hermes Study: Biomarker database developed to investigate blood-based and digital biomarkers in community-based, diverse populations clinically screened for Alzheimer's disease.
    Alzheimers Dement. 2024 Feb 28. doi: 10.1002/alz.13722.
    PubMed         Abstract available

  9. SHIM KH, Kim D, Kang MJ, Pyun JM, et al
    Subsequent correlated changes in complement component 3 and amyloid beta oligomers in the blood of patients with Alzheimer's disease.
    Alzheimers Dement. 2024 Feb 27. doi: 10.1002/alz.13734.
    PubMed         Abstract available

  10. SASNER M, Onos KD, Territo PR, Sukoff Rizzo SJ, et al
    Meeting report of the fifth annual workshop on Principles and Techniques for Improving Preclinical to Clinical Translation in Alzheimer's Disease Research.
    Alzheimers Dement. 2024 Feb 24. doi: 10.1002/alz.13742.
    PubMed         Abstract available

  11. WANG G, Li Y, Xiong C, Benzinger TLS, et al
    Examining amyloid reduction as a surrogate endpoint through latent class analysis using clinical trial data for dominantly inherited Alzheimer's disease.
    Alzheimers Dement. 2024 Feb 23. doi: 10.1002/alz.13735.
    PubMed         Abstract available


    Ann Neurol

  12. VAN EGROO M, van Someren EJW, Grinberg LT, Bennett DA, et al
    Associations of 24-Hour Rest-Activity Rhythm Fragmentation, Cognitive Decline, and Postmortem Locus Coeruleus Hypopigmentation in Alzheimer's Disease.
    Ann Neurol. 2024 Feb 26. doi: 10.1002/ana.26880.
    PubMed         Abstract available

  13. PAPP KV, Jutten RJ, Soberanes D, Weizenbaum E, et al
    Early Detection of Amyloid-Related Changes in Memory among Cognitively Unimpaired Older Adults with Daily Digital Testing.
    Ann Neurol. 2024;95:507-517.
    PubMed         Abstract available

  14. LACHNER C, Craver EC, Babulal GM, Lucas JA, et al
    Disparate Dementia Risk Factors Are Associated with Cognitive Impairment and Rates of Decline in African Americans.
    Ann Neurol. 2024;95:518-529.
    PubMed         Abstract available

  15. PHAN TX, Baratono S, Drew W, Tetreault AM, et al
    Increased Cortical Thickness in Alzheimer's Disease.
    Ann Neurol. 2024 Feb 24. doi: 10.1002/ana.26894.
    PubMed         Abstract available

  16. LI Y, Yen D, Hendrix RD, Gordon BA, et al
    Timing of Biomarker Changes in Sporadic Alzheimer's Disease in Estimated Years from Symptom Onset.
    Ann Neurol. 2024 Feb 24. doi: 10.1002/ana.26891.
    PubMed         Abstract available


    BMC Neurol

  17. RAJENDRAKUMAR AL, Arbeev KG, Bagley O, Yashin AI, et al
    The SNP rs6859 in NECTIN2 gene is associated with underlying heterogeneous trajectories of cognitive changes in older adults.
    BMC Neurol. 2024;24:78.
    PubMed         Abstract available


    Brain Res

  18. PUMO A, Legeay S
    The dichotomous activities of microglia: A potential driver for phenotypic heterogeneity in Alzheimer's disease.
    Brain Res. 2024 Feb 21:148817. doi: 10.1016/j.brainres.2024.148817.
    PubMed         Abstract available

  19. ZHANG Z, Ding C, Fu R, Wang J, et al
    Low-frequency rTMS modulated the excitability and high-frequency firing in hippocampal neurons of the Alzheimer's disease mouse model.
    Brain Res. 2024 Feb 24:148822. doi: 10.1016/j.brainres.2024.148822.
    PubMed         Abstract available


    Curr Alzheimer Res

  20. TEKADE A, Kadam P, Jagdale S, Surwade S, et al
    Exploring Potential of Nano-formulations in the Treatment of Alzheimer's Disease through Nasal Route.
    Curr Alzheimer Res. 2024 Feb 29. doi: 10.2174/0115672050290462240222092303.
    PubMed         Abstract available

  21. CHERNOV Y
    Handwriting Markers for the Onset of Alzheimer's Disease.
    Curr Alzheimer Res. 2024 Feb 28. doi: 10.2174/0115672050299338240222051023.
    PubMed         Abstract available

  22. MAZIERO MP, Rocha NP, Teixeira AL
    Antipsychotics in Alzheimer's Disease: Current Status and Therapeutic Alternatives.
    Curr Alzheimer Res. 2024 Feb 22. doi: 10.2174/0115672050287534240215052417.
    PubMed         Abstract available

  23. RODRIGUES JFR, Rodrigues LP, Filho GGMA
    Alzheimer's Disease and Suicide: An Integrative Literature Review.
    Curr Alzheimer Res. 2024 Feb 22. doi: 10.2174/0115672050292472240216052614.
    PubMed         Abstract available


    Exp Gerontol

  24. HE K, Nie L, Yang C, Liu Z, et al
    Exhaustive exercise decreases tau phosphorylation and modifies biological processes associated with the protein translation and electron transport chain in P301L tau transgenic mice.
    Exp Gerontol. 2024;187:112375.
    PubMed         Abstract available


    J Alzheimers Dis

  25. CULIBRK RA, Ebbert KA, Yeisley DJ, Chen R, et al
    Impact of Suramin on Key Pathological Features of Sporadic Alzheimer's Disease-Derived Forebrain Neurons.
    J Alzheimers Dis. 2024 Feb 24. doi: 10.3233/JAD-230600.
    PubMed         Abstract available

  26. NJOMBORO P, Lekhutlile T
    The Effect of Apathy and Depressive Syndromes on Functional Outcomes in Alzheimer's Disease.
    J Alzheimers Dis. 2024 Feb 26. doi: 10.3233/JAD-230426.
    PubMed         Abstract available

  27. VERWAERDE P, Estrella C, Burlet S, Barrier M, et al
    First-In-Human Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of AZP2006, A Synthetic Compound for the Treatment of Alzheimer's Disease and Related Diseases.
    J Alzheimers Dis. 2024 Feb 26. doi: 10.3233/JAD-220883.
    PubMed         Abstract available

  28. COGRAM P, Garduno BM, Ren B, Xu X, et al
    First International Conference on Unconventional Animal Models of Alzheimer's Disease and Aging.
    J Alzheimers Dis. 2024 Feb 20. doi: 10.3233/JAD-249004.
    PubMed         Abstract available

  29. CZUCZWAR SAJ, Kocki J, Miziak B, Bogucki J, et al
    Alpha-, Beta-, and Gamma-Secretase, Amyloid Precursor Protein, and Tau Protein Genes in the Hippocampal CA3 Subfield in an Ischemic Model of Alzheimer's Disease with Survival up to 2 Years.
    J Alzheimers Dis. 2024 Feb 19. doi: 10.3233/JAD-231333.
    PubMed         Abstract available

  30. KAMEYAMA H, Tagai K, Takasaki E, Kashibayashi T, et al
    Examining Frontal Lobe Asymmetry and Its Potential Role in Aggressive Behaviors in Early Alzheimer's Disease.
    J Alzheimers Dis. 2024 Feb 23. doi: 10.3233/JAD-231306.
    PubMed         Abstract available

  31. RAJABLI F, Seixas AA, Akgun B, Adams LD, et al
    African Ancestry Individuals with Higher Educational Attainment are Resilient to Alzheimer's Disease Measured by pTau181.
    J Alzheimers Dis. 2024 Feb 19. doi: 10.3233/JAD-231116.
    PubMed         Abstract available

  32. ACHARYA NK, Grossman HC, Clifford PM, Levin EC, et al
    A Chronic Increase in Blood-Brain Barrier Permeability Facilitates Intraneuronal Deposition of Exogenous Bloodborne Amyloid-Beta1-42 Peptide in the Brain and Leads to Alzheimer's Disease-Relevant Cognitive Changes in a Mouse Model.
    J Alzheimers Dis. 2024 Feb 20. doi: 10.3233/JAD-231028.
    PubMed         Abstract available

  33. ADAMS JA, Uryash A, Lopez JR
    Harnessing Passive Pulsatile Shear Stress for Alzheimer's Disease Prevention and Intervention.
    J Alzheimers Dis. 2024 Feb 22. doi: 10.3233/JAD-231010.
    PubMed         Abstract available

  34. SUN H, Li P, Gao L, Yang J, et al
    Altered Motor Activity Patterns within 10-Minute Timescale Predict Incident Clinical Alzheimer's Disease.
    J Alzheimers Dis. 2024 Feb 19. doi: 10.3233/JAD-230928.
    PubMed         Abstract available

  35. RAPOS PEREIRA F, George N, Dalla Barba G, Dubois B, et al
    The Memory Binding Test Detects Early Subtle Episodic Memory Decline in Preclinical Alzheimer's Disease: A Longitudinal Study.
    J Alzheimers Dis. 2024 Feb 22. doi: 10.3233/JAD-230921.
    PubMed         Abstract available

  36. NELSON D, Thompson KJ, Wang L, Wang Z, et al
    Pericyte Control of Gene Expression in the Blood-Brain Barrier Endothelium: Implications for Alzheimer's Disease.
    J Alzheimers Dis. 2024 Feb 19. doi: 10.3233/JAD-230907.
    PubMed         Abstract available

  37. VAISHNAV N, Gonzalez R, Karunungan K, Tyler A, et al
    Creating an Unprotected Class: Addressing Legal Risks in the Era of Biologically-Defined Alzheimer's Disease.
    J Alzheimers Dis. 2024 Feb 23. doi: 10.3233/JAD-230067.
    PubMed         Abstract available

  38. WANG CS, Chen PS, Tsai TY, Hou NT, et al
    Cognitive Effect of Transcranial Direct Current Stimulation on Left Dorsolateral Prefrontal Cortex in Mild Alzheimer's Disease: A Randomized, Double-Blind, Cross-Over Small-Scale Exploratory Study.
    J Alzheimers Dis. 2024 Feb 28. doi: 10.3233/JAD-240002.
    PubMed         Abstract available


  39. Retraction to: Potential Mechanisms Linking Cholesterol to Alzheimer's Disease-like Pathology in Rabbit Brain, Hippocampal Organotypic Slices, and Skeletal Muscle.
    J Alzheimers Dis. 2024 Mar 1. doi: 10.3233/JAD-239016.
    PubMed        

  40. KUMARI S, Kaur P, Singh AK, Ashar MS, et al
    Quantification of COX-2 Level in Alzheimer's Disease Patients to Develop Potential Blood-Based Biomarker for Early Diagnosis and Therapeutic Target.
    J Alzheimers Dis. 2024 Feb 24. doi: 10.3233/JAD-231445.
    PubMed         Abstract available

  41. GOHEL D, Zhang P, Gupta AK, Li Y, et al
    Sildenafil as a Candidate Drug for Alzheimer's Disease: Real-World Patient Data Observation and Mechanistic Observations from Patient-Induced Pluripotent Stem Cell-Derived Neurons.
    J Alzheimers Dis. 2024 Mar 1. doi: 10.3233/JAD-231391.
    PubMed         Abstract available

  42. LU TV, Grill JD, Gillen DL
    Study Partner Type and Adverse Event Reporting in Mild-to-Moderate Alzheimer's Disease Clinical Trials.
    J Alzheimers Dis. 2024 Feb 26. doi: 10.3233/JAD-231283.
    PubMed         Abstract available

  43. SIGURDSSON EM
    Tau Immunotherapies for Alzheimer's Disease and Related Tauopathies: Status of Trials and Insights from Preclinical Studies.
    J Alzheimers Dis. 2024 Feb 26. doi: 10.3233/JAD-231238.
    PubMed         Abstract available

  44. GARCIA-ALBERCA JM, de Rojas I, Sanchez-Mejias E, Garrido-Martin D, et al
    An Insertion Within SIRPbeta1 Shows a Dual Effect Over Alzheimer's Disease Cognitive Decline Altering the Microglial Response.
    J Alzheimers Dis. 2024 Feb 26. doi: 10.3233/JAD-231150.
    PubMed         Abstract available

  45. CHI HC, Ma LZ, Wang ZB, Sheng ZH, et al
    Associations of Frailty with Neuropsychiatric Symptoms of Alzheimer's Disease: A Longitudinal Study.
    J Alzheimers Dis. 2024 Feb 26. doi: 10.3233/JAD-231111.
    PubMed         Abstract available

  46. LI S, Lan X, Liu Y, Zhou J, et al
    Unlocking the Potential of Repetitive Transcranial Magnetic Stimulation in Alzheimer's Disease: A Meta-Analysis of Randomized Clinical Trials to Optimize Intervention Strategies.
    J Alzheimers Dis. 2024 Feb 28. doi: 10.3233/JAD-231031.
    PubMed         Abstract available

  47. KAVOOSI S, Shahraki A, Sheervalilou R
    Identification of microRNA-mRNA Regulatory Networks with Therapeutic Values in Alzheimer's Disease by Bioinformatics Analysis.
    J Alzheimers Dis. 2024 Feb 24. doi: 10.3233/JAD-230966.
    PubMed         Abstract available

  48. SABBIR MG
    Cholinergic Receptor Muscarinic 1 Co-Localized with Mitochondria in Cultured Dorsal Root Ganglion Neurons, and Its Deletion Disrupted Mitochondrial Ultrastructure in Peripheral Neurons: Implications in Alzheimer's Disease.
    J Alzheimers Dis. 2024 Feb 24. doi: 10.3233/JAD-230883.
    PubMed         Abstract available

  49. ROSSI E, Marrosu F, Saba L
    Music Therapy as a Complementary Treatment in Patients with Dementia Associated to Alzheimer's Disease: A Systematic Review.
    J Alzheimers Dis. 2024 Feb 26. doi: 10.3233/JAD-230852.
    PubMed         Abstract available

  50. YANG J, Liu X, Oveisgharan S, Zammit AR, et al
    Inferring Alzheimer's Disease Pathologic Traits from Clinical Measures in Living Adults.
    J Alzheimers Dis. 2024 Mar 1. doi: 10.3233/JAD-230639.
    PubMed         Abstract available


    J Neurol

  51. PENG M, Yuan S, Lu D, Ling Y, et al
    Dietary inflammatory index, genetic susceptibility and risk of incident dementia: a prospective cohort study from UK biobank.
    J Neurol. 2024;271:1286-1296.
    PubMed         Abstract available


    J Neurosci

  52. REN Q, Wang S, Li J, Cao K, et al
    Novel social stimulation ameliorates memory deficit in Alzheimer's disease model through activating alpha-secretase.
    J Neurosci. 2024 Feb 28:e1689232024. doi: 10.1523/JNEUROSCI.1689-23.2024.
    PubMed         Abstract available


    N Engl J Med

  53. BATEMAN RJ, Smith J, Doody RS
    Gantenerumab in Early Alzheimer's Disease. Reply.
    N Engl J Med. 2024;390:867.
    PubMed        

  54. WANG Z, Zhao B, Jia J
    Gantenerumab in Early Alzheimer's Disease.
    N Engl J Med. 2024;390:866.
    PubMed        


    Nat Rev Neurol

  55. KORCZYN AD, Grinberg LT
    Is Alzheimer disease a disease?
    Nat Rev Neurol. 2024 Feb 29. doi: 10.1038/s41582-024-00940.
    PubMed         Abstract available


    Neurobiol Aging

  56. ROBINSON B, Bhamidi S, Dayan E
    The spatial distribution of coupling between tau and neurodegeneration in amyloid-beta positive mild cognitive impairment.
    Neurobiol Aging. 2024;136:70-77.
    PubMed         Abstract available

  57. WHITMAN ET, Ryan CP, Abraham WC, Addae A, et al
    A blood biomarker of the pace of aging is associated with brain structure: replication across three cohorts.
    Neurobiol Aging. 2024;136:23-33.
    PubMed         Abstract available

  58. JANG I, Li B, Rashid B, Jacoby J, et al
    Brain structural indicators of beta-amyloid neuropathology.
    Neurobiol Aging. 2024;136:157-170.
    PubMed         Abstract available

  59. BABILONI C, Jakhar D, Tucci F, Del Percio C, et al
    Resting state electroencephalographic alpha rhythms are sensitive to Alzheimer's disease mild cognitive impairment progression at a 6-month follow-up.
    Neurobiol Aging. 2024;137:19-37.
    PubMed         Abstract available


    Neurobiol Dis

  60. LONG DM, Cravetchi O, Chow ES, Allen C, et al
    The amyloid precursor protein intracellular domain induces sleep disruptions and its nuclear localization fluctuates in circadian pacemaker neurons in Drosophila and mice.
    Neurobiol Dis. 2024;192:106429.
    PubMed         Abstract available

  61. TATO-FERNANDEZ C, Ekblad LL, Pietila E, Saunavaara V, et al
    Cognitively healthy APOE4/4 carriers show white matter impairment associated with serum NfL and amyloid-PET.
    Neurobiol Dis. 2024;192:106439.
    PubMed         Abstract available


    Neurology

  62. ACKLEY S, Calmasini C, Bouteloup V, Hill-Jarrett TG, et al
    Contribution of Global Amyloid-PET Imaging for Predicting Future Cognition in the MEMENTO Cohort.
    Neurology. 2024;102:e208054.
    PubMed         Abstract available


    Neuroscience

  63. XU M, Lin R, Wen H, Wang Y, et al
    Electroacupuncture Enhances the Functional Connectivity of Limbic System to Neocortex in the 5xFAD Mouse Model of Alzheimer's Disease.
    Neuroscience. 2024 Feb 27:S0306-4522(24)00090.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  64. MAMMERI NE, Dregni AJ, Duan P, Hong M, et al
    Structures of AT8 and PHF1 phosphomimetic tau: Insights into the posttranslational modification code of tau aggregation.
    Proc Natl Acad Sci U S A. 2024;121:e2316175121.
    PubMed         Abstract available


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