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13.06.2022

6 Alzheimers Dement
1 Am J Alzheimers Dis Other Demen
1 Am J Geriatr Psychiatry
1 BMC Geriatr
1 BMC Neurol
2 Brain
1 Dement Geriatr Cogn Disord
15 J Alzheimers Dis
2 J Am Geriatr Soc
1 J Biol Chem
1 J Neurosci
1 JAMA Intern Med
1 Nat Neurosci
1 Nat Rev Neurol
4 Neurobiol Aging
1 Neurobiol Dis
1 Neurology
1 Neurosci Lett
1 PLoS Genet
2 PLoS One
1 Proc Natl Acad Sci U S A
3 Rev Neurol (Paris)


  Retrieve available abstracts of this week’s articles:
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Single Articles


    Alzheimers Dement

  1. SANZ-BLASCO R, Ruiz-Sanchez de Leon JM, Avila-Villanueva M, Valenti-Soler M, et al
    Transition from mild cognitive impairment to normal cognition: Determining the predictors of reversion with multi-state Markov models.
    Alzheimers Dement. 2022;18:1177-1185.
    PubMed         Abstract available

  2. LIU L, Kwak H, Lawton TL, Jin SX, et al
    An ultra-sensitive immunoassay detects and quantifies soluble Abeta oligomers in human plasma.
    Alzheimers Dement. 2022;18:1186-1202.
    PubMed         Abstract available

  3. SYRJANEN JA, Campbell MR, Algeciras-Schimnich A, Vemuri P, et al
    Associations of amyloid and neurodegeneration plasma biomarkers with comorbidities.
    Alzheimers Dement. 2022;18:1128-1140.
    PubMed         Abstract available

  4. SAWA M, Overk C, Becker A, Derse D, et al
    Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model.
    Alzheimers Dement. 2022;18:1203-1234.
    PubMed         Abstract available

  5. GAO F, Lv X, Dai L, Wang Q, et al
    A combination model of AD biomarkers revealed by machine learning precisely predicts Alzheimer's dementia: China Aging and Neurodegenerative Initiative (CANDI) study.
    Alzheimers Dement. 2022 Jun 6. doi: 10.1002/alz.12700.
    PubMed         Abstract available

  6. RISCHEL EB, Gejl M, Brock B, Rungby J, et al
    In Alzheimer's disease, amyloid beta accumulation is a protective mechanism that ultimately fails.
    Alzheimers Dement. 2022 Jun 8. doi: 10.1002/alz.12701.
    PubMed         Abstract available


    Am J Alzheimers Dis Other Demen

  7. CUSTODIO N, Montesinos R, Chambergo-Michilot D, Herrera-Perez E, et al
    A Functional Assessment Tool to Distinguish Controls From Alzheimer's Disease in Lima, Peru.
    Am J Alzheimers Dis Other Demen. 2022;37:15333175221104354.
    PubMed         Abstract available


    Am J Geriatr Psychiatry

  8. TRAN D, Nguyen H, Pham T, Nguyen AT, et al
    Resources for Enhancing Alzheimer's Caregiver Health in Vietnam (REACH VN): Exploratory Analyses of Outcomes of a Cluster Randomized Controlled Trial to Test the Feasibility and Preliminary Efficacy of a Family Dementia Caregiver Intervention in Vietn
    Am J Geriatr Psychiatry. 2022 May 6. pii: S1064-7481(22)00400.
    PubMed         Abstract available


    BMC Geriatr

  9. HA J, Son NH, Park YH, Lee E, et al
    Association of cognitive enhancers and incident seizure risk in dementia: a population-based study.
    BMC Geriatr. 2022;22:480.
    PubMed         Abstract available


    BMC Neurol

  10. HE L, Chen Z, Wang J, Feng H, et al
    Expression relationship and significance of NEAT1 and miR-27a-3p in serum and cerebrospinal fluid of patients with Alzheimer's disease.
    BMC Neurol. 2022;22:203.
    PubMed         Abstract available


    Brain

  11. LEVY JP, Bezgin G, Savard M, Pascoal TA, et al
    18F-MK-6240 tau-PET in genetic frontotemporal dementia.
    Brain. 2021 Oct 19. pii: 6402002. doi: 10.1093.
    PubMed         Abstract available

  12. KAIVOLA K, Shah Z, Chia R, Scholz SW, et al
    Genetic evaluation of dementia with Lewy bodies implicates distinct disease subgroups.
    Brain. 2022;145:1757-1762.
    PubMed         Abstract available


    Dement Geriatr Cogn Disord

  13. RYU SY, Hong YJ, Ho S, Jeong JH, et al
    Subtle Cognitive Deficits Are Associated with Amyloid-beta Positivity, but Not Severity of Self-Reported Decline: Results from the CoSCo Study.
    Dement Geriatr Cogn Disord. 2022;51:159-167.
    PubMed         Abstract available


    J Alzheimers Dis

  14. HAN SH, Noh DH, Jo EJ, Kam KY, et al
    Effects of Apolipoprotein E varepsilon4 and Risk Factors on Domains of Cognition in Mild Cognitive Impairment and Dementia.
    J Alzheimers Dis. 2022;87:1181-1188.
    PubMed         Abstract available

  15. SCHWERTNER E, Pereira JB, Xu H, Secnik J, et al
    Behavioral and Psychological Symptoms of Dementia in Different Dementia Disorders: A Large-Scale Study of 10,000 Individuals.
    J Alzheimers Dis. 2022;87:1307-1318.
    PubMed         Abstract available

  16. WHITEHOUSE PJ, Saini V
    Making the Case for the Accelerated Withdrawal of Aducanumab.
    J Alzheimers Dis. 2022;87:999-1001.
    PubMed         Abstract available

  17. RIPHAGEN JM, van Hooren RWE, Kenis G, Verhey FRJ, et al
    Distinct Patterns Link the BDNF Val66Met Polymorphism to Alzheimer's Disease Pathology.
    J Alzheimers Dis. 2022 May 28. pii: JAD215353. doi: 10.3233/JAD-215353.
    PubMed         Abstract available

  18. HANNONEN S, Andberg S, Karkkainen V, Rusanen M, et al
    Shortening of Saccades as a Possible Easy-to-Use Biomarker to Detect Risk of Alzheimer's Disease.
    J Alzheimers Dis. 2022 Jun 3. pii: JAD215551. doi: 10.3233/JAD-215551.
    PubMed         Abstract available

  19. RIPPON B, Palta P, Tahmi M, Sherwood G, et al
    Plasma Amyloid and in vivo Brain Amyloid in Late Middle-Aged Hispanics.
    J Alzheimers Dis. 2022;87:1229-1238.
    PubMed         Abstract available

  20. SHIMOSAKA M, Nishimoto H, Kinoshita A
    Analysis of the Clock-Reading Ability in Patients with Cognitive Impairment: Comparison of Analog Clocks and Digital Clocks.
    J Alzheimers Dis. 2022;87:1151-1165.
    PubMed         Abstract available

  21. SHENG C, Yang K, He B, Li T, et al
    Cross-Cultural Longitudinal Study on Cognitive Decline (CLoCODE) for Subjective Cognitive Decline in China and Germany: A Protocol for Study Design.
    J Alzheimers Dis. 2022;87:1319-1333.
    PubMed         Abstract available

  22. JEONG S, Huang LK, Tsai MJ, Liao YT, et al
    Cognitive Function Associated with Gut Microbial Abundance in Sucrose and S-Adenosyl-L-Methionine (SAMe) Metabolic Pathways.
    J Alzheimers Dis. 2022;87:1115-1130.
    PubMed         Abstract available

  23. WHITEHOUSE P, Gandy S, Saini V, George DR, et al
    Making the Case for Accelerated Withdrawal of Aducanumab.
    J Alzheimers Dis. 2022;87:1003-1007.
    PubMed         Abstract available

  24. WANG Y, Li L, Zhao X, Sui S, et al
    Intestinal Microflora Changes in Patients with Mild Alzheimer's Disease in a Chinese Cohort.
    J Alzheimers Dis. 2022 May 30. pii: JAD220076. doi: 10.3233/JAD-220076.
    PubMed         Abstract available

  25. HUDA TI, Diaz MJ, Gozlan EC, Chobrutskiy A, et al
    Immunogenomics Parameters for Patient Stratification in Alzheimer's Disease.
    J Alzheimers Dis. 2022 Jun 3. pii: JAD220119. doi: 10.3233/JAD-220119.
    PubMed         Abstract available

  26. WANG Q, Shi Y, Qi X, Qi L, et al
    Platelet-Derived Amyloid-beta Protein Precursor as a Biomarker of Alzheimer's Disease.
    J Alzheimers Dis. 2022 Jun 3. pii: JAD220122. doi: 10.3233/JAD-220122.
    PubMed         Abstract available

  27. ARAUJO DC, Veloso AA, Gomes KB, Souza LC, et al
    A Novel Panel of Plasma Proteins Predicts Progression in Prodromal Alzheimer's Disease.
    J Alzheimers Dis. 2022 Jun 3. pii: JAD220256. doi: 10.3233/JAD-220256.
    PubMed         Abstract available

  28. SERWER P, Wright ET, Hunter B
    Additions to Alpha-Sheet Based Hypotheses for the Cause of Alzheimer's Disease.
    J Alzheimers Dis. 2022 May 30. pii: JAD220311. doi: 10.3233/JAD-220311.
    PubMed         Abstract available


    J Am Geriatr Soc

  29. KUFFEL RL, Byers AL, Williams B, Fortinsky R, et al
    Prevalence of dementia and mild cognitive impairment before incarceration.
    J Am Geriatr Soc. 2022;70:1792-1799.
    PubMed         Abstract available

  30. DISTEFANO MJ, Alexander GC, Polsky D, Anderson GF, et al
    Public opinion regarding U.S. Food and Drug Administration approval of aducanumab and potential policy responses: A nationally representative survey.
    J Am Geriatr Soc. 2022;70:1685-1694.
    PubMed         Abstract available


    J Biol Chem

  31. KOMATSU A, Iida I, Nasu Y, Ito G, et al
    Ammonia induces amyloidogenesis in astrocytes by promoting amyloid precursor protein translocation into the endoplasmic reticulum.
    J Biol Chem. 2022;298:101933.
    PubMed         Abstract available


    J Neurosci

  32. SHI Q, Chang C, Saliba A, Bhat MA, et al
    Microglial mTOR Activation Upregulates Trem2 and Enhances beta-Amyloid Plaque Clearance in the 5XFAD Alzheimer's Disease Model.
    J Neurosci. 2022 Jun 2. pii: JNEUROSCI.2427-21.2022.
    PubMed         Abstract available


    JAMA Intern Med

  33. WOLOSHIN S, Kesselheim AS
    What to Know About the Alzheimer Drug Aducanumab (Aduhelm).
    JAMA Intern Med. 2022 Jun 6. pii: 2792897. doi: 10.1001/jamainternmed.2022.1039.
    PubMed        


    Nat Neurosci

  34. LEE JH, Yang DS, Goulbourne CN, Im E, et al
    Faulty autolysosome acidification in Alzheimer's disease mouse models induces autophagic build-up of Abeta in neurons, yielding senile plaques.
    Nat Neurosci. 2022;25:688-701.
    PubMed         Abstract available


    Nat Rev Neurol

  35. WOOD H
    Menopause influences tau pathology.
    Nat Rev Neurol. 2022;18:317.
    PubMed        


    Neurobiol Aging

  36. MAZZEO S, Polito C, Lassi M, Bagnoli S, et al
    Loss of speech and functional impairment in Alzheimer's disease-related primary progressive aphasia: predictive factors of decline.
    Neurobiol Aging. 2022;117:59-70.
    PubMed         Abstract available

  37. VIDAL-PINEIRO D, Sorensen O, Blennow K, Capogna E, et al
    Relationship between cerebrospinal fluid neurodegeneration biomarkers and temporal brain atrophy in cognitively healthy older adults.
    Neurobiol Aging. 2022;116:80-91.
    PubMed         Abstract available

  38. SHEN B, Hernandez DG, Chitrala KN, Fanelli-Kuczmarski MT, et al
    APOE gene region methylation is associated with cognitive performance in middle-aged urban adults.
    Neurobiol Aging. 2022;116:41-48.
    PubMed         Abstract available

  39. MELIKYAN ZA, Corrada MM, Leiby AM, Sajjadi SA, et al
    Cognitive resilience to three dementia-related neuropathologies in an oldest-old man: A case report from The 90+ Study.
    Neurobiol Aging. 2022;116:12-15.
    PubMed         Abstract available


    Neurobiol Dis

  40. TROUTWINE BR, Strope TA, Franczak E, Lysaker CR, et al
    Mitochondrial function and Abeta in Alzheimer's disease postmortem brain.
    Neurobiol Dis. 2022 Jun 3:105781. doi: 10.1016/j.nbd.2022.105781.
    PubMed         Abstract available


    Neurology

  41. TANG B, Wang Y, Jiang X, Thambisetty M, et al
    Genetic Variation in Targets of Anti-diabetic Drugs and Alzheimer Disease Risk: A Mendelian Randomization Study.
    Neurology. 2022 Jun 2. pii: WNL.0000000000200771.
    PubMed         Abstract available


    Neurosci Lett

  42. AAMERI R, Ghorbani H, Reza Bazrafshan H, Zahra Gharib F, et al
    Iranian thyme honey plays behavioral, cellular and molecular important roles as an amazing preventive and therapeutic agent in the brain of Alzheimer's rat model.
    Neurosci Lett. 2022;783:136702.
    PubMed         Abstract available


    PLoS Genet

  43. DE LA FUENTE J, Grotzinger AD, Marioni RE, Nivard MG, et al
    Integrated analysis of direct and proxy genome wide association studies highlights polygenicity of Alzheimer's disease outside of the APOE region.
    PLoS Genet. 2022;18:e1010208.
    PubMed         Abstract available


    PLoS One

  44. GARCIA MARIN ID, Camarillo Lopez RH, Martinez OA, Padilla-Martinez II, et al
    New compounds from heterocyclic amines scaffold with multitarget inhibitory activity on Abeta aggregation, AChE, and BACE1 in the Alzheimer disease.
    PLoS One. 2022;17:e0269129.
    PubMed         Abstract available

  45. SELF W, Awwad K, Savaryn JP, Schulz M, et al
    An immuno-enrichment free, validated quantification of tau protein in human CSF by LC-MS/MS.
    PLoS One. 2022;17:e0269157.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  46. ENINGER T, Muller SA, Bacioglu M, Schweighauser M, et al
    Signatures of glial activity can be detected in the CSF proteome.
    Proc Natl Acad Sci U S A. 2022;119:e2119804119.
    PubMed         Abstract available


    Rev Neurol (Paris)

  47. BLANC F, Bousiges O
    Biomarkers and diagnosis of dementia with Lewy bodies including prodromal: Practical aspects.
    Rev Neurol (Paris). 2022;178:472-483.
    PubMed         Abstract available

  48. CHETELAT G
    How to use neuroimaging biomarkers in the diagnosis framework of neurodegenerative diseases?
    Rev Neurol (Paris). 2022;178:490-497.
    PubMed         Abstract available

  49. BAKER J, Schott JM
    AD and its comorbidities: An obstacle to develop a clinically efficient treatment?
    Rev Neurol (Paris). 2022;178:450-459.
    PubMed         Abstract available


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