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Articles published in Alzheimers Dement

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Single Articles

    June 2022
  1. WINGO TS, Gerasimov ES, Canon SM, Lah JJ, et al
    Alzheimer's disease genetic burden is associated with mid-life depression among persons with normal cognition.
    Alzheimers Dement. 2022 Jun 21. doi: 10.1002/alz.12716.
    PubMed     Abstract available

  2. CULLEN NC, Janelidze S, Mattsson-Carlgren N, Palmqvist S, et al
    Test-retest variability of plasma biomarkers in Alzheimer's disease and its effects on clinical prediction models.
    Alzheimers Dement. 2022 Jun 14. doi: 10.1002/alz.12706.
    PubMed     Abstract available

  3. DELVENNE A, Gobom J, Tijms B, Bos I, et al
    Cerebrospinal fluid proteomic profiling of individuals with mild cognitive impairment and suspected non-Alzheimer's disease pathophysiology.
    Alzheimers Dement. 2022 Jun 14. doi: 10.1002/alz.12713.
    PubMed     Abstract available

  4. SINGH NA, Tosakulwong N, Graff-Radford J, Machulda MM, et al
    APOE epsilon4 influences medial temporal atrophy and tau deposition in atypical Alzheimer's disease.
    Alzheimers Dement. 2022 Jun 12. doi: 10.1002/alz.12711.
    PubMed     Abstract available

  5. RISCHEL EB, Gejl M, Brock B, Rungby J, et al
    In Alzheimer's disease, amyloid beta accumulation is a protective mechanism that ultimately fails.
    Alzheimers Dement. 2022 Jun 8. doi: 10.1002/alz.12701.
    PubMed     Abstract available

  6. GAO F, Lv X, Dai L, Wang Q, et al
    A combination model of AD biomarkers revealed by machine learning precisely predicts Alzheimer's dementia: China Aging and Neurodegenerative Initiative (CANDI) study.
    Alzheimers Dement. 2022 Jun 6. doi: 10.1002/alz.12700.
    PubMed     Abstract available

  7. GUSTAVSSON A, Norton N, Fast T, Frolich L, et al
    Global estimates on the number of persons across the Alzheimer's disease continuum.
    Alzheimers Dement. 2022 Jun 2. doi: 10.1002/alz.12694.
    PubMed     Abstract available

  8. SAWA M, Overk C, Becker A, Derse D, et al
    Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model.
    Alzheimers Dement. 2022;18:1203-1234.
    PubMed     Abstract available

  9. SYRJANEN JA, Campbell MR, Algeciras-Schimnich A, Vemuri P, et al
    Associations of amyloid and neurodegeneration plasma biomarkers with comorbidities.
    Alzheimers Dement. 2022;18:1128-1140.
    PubMed     Abstract available

  10. LIU L, Kwak H, Lawton TL, Jin SX, et al
    An ultra-sensitive immunoassay detects and quantifies soluble Abeta oligomers in human plasma.
    Alzheimers Dement. 2022;18:1186-1202.
    PubMed     Abstract available

  11. SANZ-BLASCO R, Ruiz-Sanchez de Leon JM, Avila-Villanueva M, Valenti-Soler M, et al
    Transition from mild cognitive impairment to normal cognition: Determining the predictors of reversion with multi-state Markov models.
    Alzheimers Dement. 2022;18:1177-1185.
    PubMed     Abstract available

    May 2022
  12. VOGLEIN J, Franzmeier N, Morris JC, Dieterich M, et al
    Patterns and implications of neurological examination findings in autosomal dominant Alzheimer disease.
    Alzheimers Dement. 2022 May 24. doi: 10.1002/alz.12684.
    PubMed     Abstract available

  13. HU Y, Zhang Y, Zhang H, Gao S, et al
    Mendelian randomization highlights causal association between genetically increased C-reactive protein levels and reduced Alzheimer's disease risk.
    Alzheimers Dement. 2022 May 22. doi: 10.1002/alz.12687.

  14. LUO J, Thomassen JQ, Hegazy SH, Rasmussen IJ, et al
    Reply to "Mendelian randomization highlights causal association between genetically increased C-reactive protein levels and reduced Alzheimer's disease risk".
    Alzheimers Dement. 2022 May 22. doi: 10.1002/alz.12688.

  15. ASHLEIGH T, Swerdlow RH, Beal MF
    The role of mitochondrial dysfunction in Alzheimer's disease pathogenesis.
    Alzheimers Dement. 2022 May 6. doi: 10.1002/alz.12683.
    PubMed     Abstract available

  16. SEXTON C, Snyder H, Beher D, Boxer AL, et al
    Current directions in tau research: Highlights from Tau 2020.
    Alzheimers Dement. 2022;18:988-1007.
    PubMed     Abstract available

  17. IMBIMBO BP, Ippati S, Watling M, Balducci C, et al
    A critical appraisal of tau-targeting therapies for primary and secondary tauopathies.
    Alzheimers Dement. 2022;18:1008-1037.
    PubMed     Abstract available

  18. PERRY BL, McConnell WR, Coleman ME, Roth AR, et al
    Why the cognitive "fountain of youth" may be upstream: Pathways to dementia risk and resilience through social connectedness.
    Alzheimers Dement. 2022;18:934-941.
    PubMed     Abstract available

    April 2022
  19. CHANG R, Trushina E, Zhu K, Zaidi SSA, et al
    Predictive metabolic networks reveal sex- and APOE genotype-specific metabolic signatures and drivers for precision medicine in Alzheimer's disease.
    Alzheimers Dement. 2022 Apr 28. doi: 10.1002/alz.12675.
    PubMed     Abstract available

  20. PARK SY, Setiawan VW, White LR, Wu AH, et al
    Modifying effects of race and ethnicity and APOE on the association of physical activity with risk of Alzheimer's disease and related dementias.
    Alzheimers Dement. 2022 Apr 27. doi: 10.1002/alz.12677.
    PubMed     Abstract available

  21. JESSEN F, Wolfsgruber S, Kleineindam L, Spottke A, et al
    Subjective cognitive decline and stage 2 of Alzheimer disease in patients from memory centers.
    Alzheimers Dement. 2022 Apr 22. doi: 10.1002/alz.12674.
    PubMed     Abstract available

  22. QUAN L, Moreno-Gonzalez I, Xie Z, Gamez N, et al
    A near-infrared probe for detecting and interposing amyloid beta oligomerization in early Alzheimer's disease.
    Alzheimers Dement. 2022 Apr 18. doi: 10.1002/alz.12673.
    PubMed     Abstract available

  23. TJANDRA D, Migrino RQ, Giordani B, Wiens J, et al
    Use of blood pressure measurements extracted from the electronic health record in predicting Alzheimer's disease: A retrospective cohort study at two medical centers.
    Alzheimers Dement. 2022 Apr 16. doi: 10.1002/alz.12676.
    PubMed     Abstract available

  24. TA PARK VM, Meyer OL, Tsoh JY, Kanaya AM, et al
    The Collaborative Approach for Asian Americans and Pacific Islanders Research and Education (CARE): A recruitment registry for Alzheimer's disease and related dementias, aging, and caregiver-related research.
    Alzheimers Dement. 2022 Apr 14. doi: 10.1002/alz.12667.
    PubMed     Abstract available

  25. MARTINEZ AE, Weissberger G, Kuklenyik Z, He X, et al
    The small HDL particle hypothesis of Alzheimer's disease.
    Alzheimers Dement. 2022 Apr 13. doi: 10.1002/alz.12649.
    PubMed     Abstract available

  26. MIELKE MM, Aggarwal NT, Vila-Castelar C, Agarwal P, et al
    Consideration of sex and gender in Alzheimer's disease and related disorders from a global perspective.
    Alzheimers Dement. 2022 Apr 8. doi: 10.1002/alz.12662.
    PubMed     Abstract available

  27. WANG Y, Li M, Kazis LE, Xia W, et al
    Clinical outcomes of COVID-19 infection among patients with Alzheimer's disease or mild cognitive impairment.
    Alzheimers Dement. 2022 Apr 4. doi: 10.1002/alz.12665.
    PubMed     Abstract available

  28. LUCKETT PH, Chen C, Gordon BA, Wisch J, et al
    Biomarker clustering in autosomal dominant Alzheimer's disease.
    Alzheimers Dement. 2022 Apr 1. doi: 10.1002/alz.12661.
    PubMed     Abstract available

  29. NEUPANE A, Lenny B, Budde JP, Wang F, et al
    Replication study of AD-associated rare variants.
    Alzheimers Dement. 2022;18:858-862.

  30. AKINYEMI RO, Yaria J, Ojagbemi A, Guerchet M, et al
    Dementia in Africa: Current evidence, knowledge gaps, and future directions.
    Alzheimers Dement. 2022;18:790-809.
    PubMed     Abstract available

  31. MURA T, Coley N, Amieva H, Berr C, et al
    Cognitive decline as an outcome and marker of progression toward dementia, in early preventive trials.
    Alzheimers Dement. 2022;18:676-687.
    PubMed     Abstract available

  32. LINDBOHM JV, Mars N, Walker KA, Singh-Manoux A, et al
    Plasma proteins, cognitive decline, and 20-year risk of dementia in the Whitehall II and Atherosclerosis Risk in Communities studies.
    Alzheimers Dement. 2022;18:612-624.
    PubMed     Abstract available

  33. POURHADI N, Morch LS, Holm EA, Torp-Pedersen CT, et al
    Vaginal estrogen and association with dementia: A nationwide population-based study.
    Alzheimers Dement. 2022;18:625-634.
    PubMed     Abstract available

  34. MIELKE MM, Aakre JA, Algeciras-Schimnich A, Proctor NK, et al
    Comparison of CSF phosphorylated tau 181 and 217 for cognitive decline.
    Alzheimers Dement. 2022;18:602-611.
    PubMed     Abstract available

  35. CASANOVA R, Hsu FC, Barnard RT, Anderson AM, et al
    Comparing data-driven and hypothesis-driven MRI-based predictors of cognitive impairment in individuals from the Atherosclerosis Risk in Communities (ARIC) study.
    Alzheimers Dement. 2022;18:561-571.
    PubMed     Abstract available

  36. YANG HS, Zhang C, Carlyle BC, Zhen SY, et al
    Plasma IL-12/IFN-gamma axis predicts cognitive trajectories in cognitively unimpaired older adults.
    Alzheimers Dement. 2022;18:645-653.
    PubMed     Abstract available

    March 2022
  37. BRODY M, Agronin M, Herskowitz BJ, Bookheimer SY, et al
    Results and insights from a phase I clinical trial of Lomecel-B for Alzheimer's disease.
    Alzheimers Dement. 2022 Mar 31. doi: 10.1002/alz.12651.
    PubMed     Abstract available

  38. ZHANG X, Tong T, Chang A, Ang TFA, et al
    Midlife lipid and glucose levels are associated with Alzheimer's disease.
    Alzheimers Dement. 2022 Mar 23. doi: 10.1002/alz.12641.
    PubMed     Abstract available

  39. JACOBS HIL, Becker JA, Kwong K, Munera D, et al
    Waning locus coeruleus integrity precedes cortical tau accrual in preclinical autosomal dominant Alzheimer's disease.
    Alzheimers Dement. 2022 Mar 17. doi: 10.1002/alz.12656.
    PubMed     Abstract available

  40. LI P, Gao L, Yu L, Zheng X, et al
    Daytime napping and Alzheimer's dementia: A potential bidirectional relationship.
    Alzheimers Dement. 2022 Mar 17. doi: 10.1002/alz.12636.
    PubMed     Abstract available

  41. COE NB, White L, Oney M, Basu A, et al
    Public spending on acute and long-term care for Alzheimer's disease and related dementias.
    Alzheimers Dement. 2022 Mar 16. doi: 10.1002/alz.12657.
    PubMed     Abstract available

  42. 2022 Alzheimer's disease facts and figures.
    Alzheimers Dement. 2022 Mar 14. doi: 10.1002/alz.12638.
    PubMed     Abstract available

  43. LIU L, Lauro BM, He A, Lee H, et al
    Identification of the Abeta37/42 peptide ratio in CSF as an improved Abeta biomarker for Alzheimer's disease.
    Alzheimers Dement. 2022 Mar 12. doi: 10.1002/alz.12646.
    PubMed     Abstract available

  44. WINDER Z, Sudduth TL, Anderson S, Patel E, et al
    Examining the association between blood-based biomarkers and human post mortem neuropathology in the University of Kentucky Alzheimer's Disease Research Center autopsy cohort.
    Alzheimers Dement. 2022 Mar 10. doi: 10.1002/alz.12639.
    PubMed     Abstract available

  45. BREITNER JCS, Dodge HH, Khachaturian ZS, Khachaturian AS, et al
    "Exceptions that prove the rule"-Why have clinical trials failed to show efficacy of risk factor interventions suggested by observational studies of the dementia-Alzheimer's disease syndrome?
    Alzheimers Dement. 2022 Mar 4. doi: 10.1002/alz.12633.

  46. Alzheimer's Association welcomes new Medical and Scientific Advisory Group members.
    Alzheimers Dement. 2022 Mar 4. doi: 10.1002/alz.12621.

  47. O'BRYANT SE, Petersen M, Hall J, Johnson LA, et al
    Medical comorbidities and ethnicity impact plasma Alzheimer's disease biomarkers: Important considerations for clinical trials and practice.
    Alzheimers Dement. 2022 Mar 2. doi: 10.1002/alz.12647.
    PubMed     Abstract available

  48. CONNOLLY K, Lehoux M, O'Rourke R, Assetta B, et al
    Potential role of chitinase-3-like protein 1 (CHI3L1/YKL-40) in neurodegeneration and Alzheimer's disease.
    Alzheimers Dement. 2022 Mar 2. doi: 10.1002/alz.12612.
    PubMed     Abstract available

  49. STOCKER H, Beyer L, Perna L, Rujescu D, et al
    Association of plasma biomarkers, p-tau181, glial fibrillary acidic protein, and neurofilament light, with intermediate and long-term clinical Alzheimer's disease risk: Results from a prospective cohort followed over 17 years.
    Alzheimers Dement. 2022 Mar 2. doi: 10.1002/alz.12614.
    PubMed     Abstract available

  50. CUMMINGS J, Salloway S
    Aducanumab: Appropriate use recommendations.
    Alzheimers Dement. 2022;18:531-533.

  51. PETERSON A, Clapp J, Largent EA, Harkins K, et al
    What is paradoxical lucidity? The answer begins with its definition.
    Alzheimers Dement. 2022;18:513-521.
    PubMed     Abstract available

  52. BARIL AA, Beiser AS, Sanchez E, Mysliwiec V, et al
    Insomnia symptom severity and cognitive performance: Moderating role of APOE genotype.
    Alzheimers Dement. 2022;18:408-421.
    PubMed     Abstract available

    February 2022
  53. GIETL AF, Frisoni GB
    Early termination of pivotal trials in Alzheimer's disease-Preserving optimal value for participants and science.
    Alzheimers Dement. 2022 Feb 27. doi: 10.1002/alz.12605.
    PubMed     Abstract available

  54. KETCHUM FB, Chin NA, Grill J, Gleason CE, et al
    Moving beyond disclosure: Stages of care in preclinical Alzheimer's disease biomarker testing.
    Alzheimers Dement. 2022 Feb 25. doi: 10.1002/alz.12620.
    PubMed     Abstract available

  55. ASHFORD MT, Raman R, Miller G, Donohue MC, et al
    Screening and enrollment of underrepresented ethnocultural and educational populations in the Alzheimer's Disease Neuroimaging Initiative (ADNI).
    Alzheimers Dement. 2022 Feb 25. doi: 10.1002/alz.12640.
    PubMed     Abstract available

    Biofluid-based biomarkers for Alzheimer's disease-related pathologies: An update and synthesis of the literature.
    Alzheimers Dement. 2022 Feb 25. doi: 10.1002/alz.12618.
    PubMed     Abstract available

  57. XIONG C, Luo J, Schindler SE, Fagan AM, et al
    Racial differences in longitudinal Alzheimer's disease biomarkers among cognitively normal adults.
    Alzheimers Dement. 2022 Feb 25. doi: 10.1002/alz.12608.
    PubMed     Abstract available

  58. MONI F, Petersen ME, Zhang F, Lao PJ, et al
    Probing the proteome to explore potential correlates of increased Alzheimer's-related cerebrovascular disease in adults with Down syndrome.
    Alzheimers Dement. 2022 Feb 24. doi: 10.1002/alz.12627.
    PubMed     Abstract available

  59. LEVIN J, Voglein J, Quiroz YT, Bateman RJ, et al
    Testing the amyloid cascade hypothesis: Prevention trials in autosomal dominant Alzheimer disease.
    Alzheimers Dement. 2022 Feb 24. doi: 10.1002/alz.12624.
    PubMed     Abstract available

  60. QUIROZ YT, Solis M, Aranda MP, Arbaje AI, et al
    Addressing the disparities in dementia risk, early detection and care in Latino populations: Highlights from the second Latinos & Alzheimer's Symposium.
    Alzheimers Dement. 2022 Feb 24. doi: 10.1002/alz.12589.
    PubMed     Abstract available

  61. SEXTON C, Solis M, Aharon-Peretz J, Alexopoulos P, et al
    Alzheimer's disease research progress in the Mediterranean region: The Alzheimer's Association International Conference Satellite Symposium.
    Alzheimers Dement. 2022 Feb 20. doi: 10.1002/alz.12588.
    PubMed     Abstract available

  62. MECCA AP, O'Dell RS, Sharp ES, Banks ER, et al
    Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [(11) C]UCB-J.
    Alzheimers Dement. 2022 Feb 17. doi: 10.1002/alz.12582.
    PubMed     Abstract available

  63. SUCHY-DICEY A, Howard B, Longstreth WT Jr, Reiman EM, et al
    APOE genotype, hippocampus, and cognitive markers of Alzheimer's disease in American Indians: Data from the Strong Heart Study.
    Alzheimers Dement. 2022 Feb 10. doi: 10.1002/alz.12573.
    PubMed     Abstract available

  64. KRELL-ROESCH J, Rakusa M, Syrjanen JA, van Harten AC, et al
    Association between CSF biomarkers of Alzheimer's disease and neuropsychiatric symptoms: Mayo Clinic Study of Aging.
    Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12557.
    PubMed     Abstract available

  65. CLAES C, England WE, Danhash EP, Kiani Shabestari S, et al
    The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model.
    Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12577.
    PubMed     Abstract available

  66. HU WT
    Reporting and social construction of race in Alzheimer's disease clinical trials.
    Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12609.

  67. ASTILLERO-LOPEZ V, Gonzalez-Rodriguez M, Villar-Conde S, Flores-Cuadrado A, et al
    Neurodegeneration and astrogliosis in the entorhinal cortex in Alzheimer's disease: Stereological layer-specific assessment and proteomic analysis.
    Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12580.
    PubMed     Abstract available

  68. FLACH M, Leu C, Martinisi A, Skachokova Z, et al
    Trans-seeding of Alzheimer-related tau protein by a yeast prion.
    Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12581.
    PubMed     Abstract available

  69. PRADOS MJ, Liu Y, Jun H, Lam J, et al
    Projecting the long-term societal value of a disease-modifying treatment for Alzheimer's disease in the United States.
    Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12578.
    PubMed     Abstract available

  70. BABULAL GM, Franzen S, Abner EL, Smith JE, et al
    Diversity in Alzheimer's disease drug trials: Reflections on reporting and social construction of race.
    Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12611.

  71. JUN GR, You Y, Zhu C, Meng G, et al
    Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE varepsilon2 for Alzheimer's disease.
    Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12607.
    PubMed     Abstract available

  72. VARDARAJAN BN, Reyes-Dumeyer D, Piriz AL, Lantigua RA, et al
    Progranulin mutations in clinical and neuropathological Alzheimer's disease.
    Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12567.
    PubMed     Abstract available

  73. REIKEN S, Sittenfeld L, Dridi H, Liu Y, et al
    Alzheimer's-like signaling in brains of COVID-19 patients.
    Alzheimers Dement. 2022 Feb 3. doi: 10.1002/alz.12558.
    PubMed     Abstract available

  74. RUTHIRAKUHAN M, Ismail Z, Herrmann N, Gallagher D, et al
    Mild behavioral impairment is associated with progression to Alzheimer's disease: A clinicopathological study.
    Alzheimers Dement. 2022 Feb 1. doi: 10.1002/alz.12519.
    PubMed     Abstract available

  75. REIMAN EM, Mattke S, Kordower JH, Khachaturian ZS, et al
    Developing a pathway to support the appropriate, affordable, and widespread use of effective Alzheimer's prevention drugs.
    Alzheimers Dement. 2022 Feb 1. doi: 10.1002/alz.12533.

  76. Applications being accepted for the Alzheimer's Association Interdisciplinary Summer Research Institute.
    Alzheimers Dement. 2022 Feb 1. doi: 10.1002/alz.12585.

  77. VILA-CASTELAR C, Tariot PN, Sink KM, Clayton D, et al
    Sex differences in cognitive resilience in preclinical autosomal-dominant Alzheimer's disease carriers and non-carriers: Baseline findings from the API ADAD Colombia Trial.
    Alzheimers Dement. 2022 Feb 1. doi: 10.1002/alz.12552.
    PubMed     Abstract available

  78. WAGNER M, Wilson RS, Leurgans SE, Boyle PA, et al
    Quantifying longitudinal cognitive resilience to Alzheimer's disease and other neuropathologies.
    Alzheimers Dement. 2022 Feb 1. doi: 10.1002/alz.12576.
    PubMed     Abstract available

  79. ERATNE D, Loi SM, Li QX, Stehmann C, et al
    Cerebrospinal fluid neurofilament light chain differentiates primary psychiatric disorders from rapidly progressive, Alzheimer's disease and frontotemporal disorders in clinical settings.
    Alzheimers Dement. 2022 Feb 1. doi: 10.1002/alz.12549.
    PubMed     Abstract available

  80. O'BRYANT S, Petersen M, Hall J, Johnson L, et al
    Characterizing plasma NfL in a community-dwelling multi-ethnic cohort: Results from the HABLE study.
    Alzheimers Dement. 2022;18:240-250.
    PubMed     Abstract available

  81. NAUEN DW, Troncoso JC
    Amyloid-beta is present in human lymph nodes and greatly enriched in those of the cervical region.
    Alzheimers Dement. 2022;18:205-210.
    PubMed     Abstract available

  82. KREISL WC, Lao PJ, Johnson A, Tomljanovic Z, et al
    Patterns of tau pathology identified with (18) F-MK-6240 PET imaging.
    Alzheimers Dement. 2022;18:272-282.
    PubMed     Abstract available

  83. SCHMUTTE T, Olfson M, Maust DT, Xie M, et al
    Suicide risk in first year after dementia diagnosis in older adults.
    Alzheimers Dement. 2022;18:262-271.
    PubMed     Abstract available

    January 2022
  84. CALDWELL AB, Liu Q, Zhang C, Schroth GP, et al
    Endotype reversal as a novel strategy for screening drugs targeting familial Alzheimer's disease.
    Alzheimers Dement. 2022 Jan 27. doi: 10.1002/alz.12553.
    PubMed     Abstract available

  85. WANG T, Huynh K, Giles C, Mellett NA, et al
    APOE epsilon2 resilience for Alzheimer's disease is mediated by plasma lipid species: Analysis of three independent cohort studies.
    Alzheimers Dement. 2022 Jan 25. doi: 10.1002/alz.12538.
    PubMed     Abstract available

  86. JORDA-SIQUIER T, Petrel M, Kouskoff V, Smailovic U, et al
    APP accumulates with presynaptic proteins around amyloid plaques: A role for presynaptic mechanisms in Alzheimer's disease?
    Alzheimers Dement. 2022 Jan 25. doi: 10.1002/alz.12546.
    PubMed     Abstract available

  87. FRONTERA JA, Boutajangout A, Masurkar AV, Betensky RA, et al
    Comparison of serum neurodegenerative biomarkers among hospitalized COVID-19 patients versus non-COVID subjects with normal cognition, mild cognitive impairment, or Alzheimer's dementia.
    Alzheimers Dement. 2022 Jan 13. doi: 10.1002/alz.12556.
    PubMed     Abstract available

  88. YAO J, Liu Y, Sun B, Zhan X, et al
    Increased RyR2 open probability induces neuronal hyperactivity and memory loss with or without Alzheimer's disease-causing gene mutations.
    Alzheimers Dement. 2022 Jan 5. doi: 10.1002/alz.12543.
    PubMed     Abstract available

  89. NAZARIAN A, Loika Y, He L, Culminskaya I, et al
    Genome-wide analysis identified abundant genetic modulators of contributions of the apolipoprotein E alleles to Alzheimer's disease risk.
    Alzheimers Dement. 2022 Jan 3. doi: 10.1002/alz.12540.
    PubMed     Abstract available

  90. REYES-DUMEYER D, Faber K, Vardarajan B, Goate A, et al
    The National Institute on Aging Late-Onset Alzheimer's Disease Family Based Study: A resource for genetic discovery.
    Alzheimers Dement. 2022 Jan 3. doi: 10.1002/alz.12514.
    PubMed     Abstract available

  91. QIU S, Hu Y, Cheng L
    BIN1 rs744373 located in enhancers of brain tissues upregulates BIN1 mRNA expression, thereby leading to Alzheimer's disease.
    Alzheimers Dement. 2022 Jan 3. doi: 10.1002/alz.12548.

  92. ZAMOLODCHIKOV D, Duffield M, Macdonald LE, Alessandri-Haber N, et al
    Accumulation of high molecular weight kininogen in the brains of Alzheimer's disease patients may affect microglial function by altering phagocytosis and lysosomal cathepsin activity.
    Alzheimers Dement. 2022 Jan 3. doi: 10.1002/alz.12531.
    PubMed     Abstract available

  93. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring announces new editor-in-chief for open access, peer reviewed journal.
    Alzheimers Dement. 2022 Jan 3. doi: 10.1002/alz.12517.

    Solomon Carter Fuller: Alzheimer's contemporary and American pioneer.
    Alzheimers Dement. 2022 Jan 3. doi: 10.1002/alz.12551.

  95. JAKEL L, De Kort AM, Klijn CJM, Schreuder FHBM, et al
    Prevalence of cerebral amyloid angiopathy: A systematic review and meta-analysis.
    Alzheimers Dement. 2022;18:10-28.
    PubMed     Abstract available

  96. ZHAO Y, Kuca K, Wu W, Wang X, et al
    Hypothesis: JNK signaling is a therapeutic target of neurodegenerative diseases.
    Alzheimers Dement. 2022;18:152-158.
    PubMed     Abstract available

  97. BUTT OH, Meeker KL, Wisch JK, Schindler SE, et al
    Network dysfunction in cognitively normal APOE epsilon4 carriers is related to subclinical tau.
    Alzheimers Dement. 2022;18:116-126.
    PubMed     Abstract available

  98. VOGT NM, Hunt JFV, Adluru N, Ma Y, et al
    Interaction of amyloid and tau on cortical microstructure in cognitively unimpaired adults.
    Alzheimers Dement. 2022;18:65-76.
    PubMed     Abstract available

    December 2021
  99. DELABY C, Teunissen CE, Blennow K, Alcolea D, et al
    Clinical reporting following the quantification of cerebrospinal fluid biomarkers in Alzheimer's disease: An international overview.
    Alzheimers Dement. 2021 Dec 22. doi: 10.1002/alz.12545.
    PubMed     Abstract available

  100. MING C, Wang M, Wang Q, Neff R, et al
    Whole genome sequencing-based copy number variations reveal novel pathways and targets in Alzheimer's disease.
    Alzheimers Dement. 2021 Dec 17. doi: 10.1002/alz.12507.
    PubMed     Abstract available

  101. HAWKINSON TR, Clarke HA, Young LEA, Conroy LR, et al
    In situ spatial glycomic imaging of mouse and human Alzheimer's disease brains.
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    Alzheimers Dement. 2020 Nov 16. doi: 10.1002/alz.12224.
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  304. JESSEN F, Kleineidam L, Wolfsgruber S, Bickel H, et al
    Prediction of dementia of Alzheimer type by different types of subjective cognitive decline.
    Alzheimers Dement. 2020 Nov 2. doi: 10.1002/alz.12163.
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  305. Alzheimer's Association pays tribute to former Chief Science Officer William (Bill) Thies, PhD.
    Alzheimers Dement. 2020;16:1600-1605.

    October 2020
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    Long genes are more frequently affected by somatic mutations and show reduced expression in Alzheimer's disease: Implications for disease etiology.
    Alzheimers Dement. 2020 Oct 19. doi: 10.1002/alz.12211.
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  307. ARNSTEN AFT, Datta D, Tredici KD, Braak H, et al
    Hypothesis: Tau pathology is an initiating factor in sporadic Alzheimer's disease.
    Alzheimers Dement. 2020 Oct 19. doi: 10.1002/alz.12192.
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  308. WESSELS AM, Lines C, Stern RA, Kost J, et al
    Cognitive outcomes in trials of two BACE inhibitors in Alzheimer's disease.
    Alzheimers Dement. 2020 Oct 13. doi: 10.1002/alz.12164.
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  309. MECCA AP, van Dyck CH
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association.
    Alzheimers Dement. 2020 Oct 12. doi: 10.1002/alz.12190.

  310. SNYDER PJ, Alber J, Alt C, Bain LJ, et al
    Retinal imaging in Alzheimer's and neurodegenerative diseases.
    Alzheimers Dement. 2020 Oct 8. doi: 10.1002/alz.12179.
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  311. THUNELL J, Chen Y, Joyce G, Barthold D, et al
    Drug therapies for chronic conditions and risk of Alzheimer's disease and related dementias: A scoping review.
    Alzheimers Dement. 2020 Oct 8. doi: 10.1002/alz.12175.
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  312. JAIN S, Rosenbaum PR, Reiter JG, Hoffman G, et al
    Using Medicare claims in identifying Alzheimer's disease and related dementias.
    Alzheimers Dement. 2020 Oct 8. doi: 10.1002/alz.12199.
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  313. HOU X, Watzlawik JO, Cook C, Liu CC, et al
    Mitophagy alterations in Alzheimer's disease are associated with granulovacuolar degeneration and early tau pathology.
    Alzheimers Dement. 2020 Oct 8. doi: 10.1002/alz.12198.
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  314. BUBU OM, Umasabor-Bubu OQ, Turner AD, Parekh A, et al
    Self-reported obstructive sleep apnea, amyloid and tau burden, and Alzheimer's disease time-dependent progression.
    Alzheimers Dement. 2020 Oct 8. doi: 10.1002/alz.12184.
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    September 2020
  315. FRANCESCO DL, Koch G
    Synaptic impairment: The new battlefield of Alzheimer's disease.
    Alzheimers Dement. 2020 Sep 18. doi: 10.1002/alz.12189.

  316. 36-month LipiDiDiet multinutrient clinical trial in prodromal Alzheimer's disease.
    Alzheimers Dement. 2020 Sep 13. doi: 10.1002/alz.12172.
    PubMed     Abstract available

  317. JIA L, Xu H, Chen S, Wang X, et al
    The APOE epsilon4 exerts differential effects on familial and other subtypes of Alzheimer's disease.
    Alzheimers Dement. 2020 Sep 3. doi: 10.1002/alz.12153.
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  318. DE LEON J, Grasso SM, Welch A, Miller Z, et al
    Effects of bilingualism on age at onset in two clinical Alzheimer's disease variants.
    Alzheimers Dement. 2020 Sep 3. doi: 10.1002/alz.12170.
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    August 2020
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    Tau and apolipoprotein E modulate cerebrovascular tight junction integrity independent of cerebral amyloid angiopathy in Alzheimer's disease.
    Alzheimers Dement. 2020 Aug 22. doi: 10.1002/alz.12104.
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  320. FRISONI GB, Molinuevo JL, Altomare D, Carrera E, et al
    Precision prevention of Alzheimer's and other dementias: Anticipating future needs in the control of risk factors and implementation of disease-modifying therapies.
    Alzheimers Dement. 2020 Aug 20. doi: 10.1002/alz.12132.
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  321. FINSTERWALDER S, Vlegels N, Gesierich B, Araque Caballero MA, et al
    Small vessel disease more than Alzheimer's disease determines diffusion MRI alterations in memory clinic patients.
    Alzheimers Dement. 2020 Aug 18. doi: 10.1002/alz.12150.
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  322. LIN PJ, Cohen JT, Neumann PJ
    Preparing the health-care system to pay for new Alzheimer's drugs.
    Alzheimers Dement. 2020 Aug 18. doi: 10.1002/alz.12155.
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  323. DENNY A, Streitz M, Stock K, Balls-Berry JE, et al
    Perspective on the "African American participation in Alzheimer disease research: Effective strategies" workshop, 2018.
    Alzheimers Dement. 2020 Aug 17. doi: 10.1002/alz.12160.
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  324. WU CY, Ouk M, Wong YY, Anita NZ, et al
    Relationships between memory decline and the use of metformin or DPP4 inhibitors in people with type 2 diabetes with normal cognition or Alzheimer's disease, and the role APOE carrier status.
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  325. MOK VCT, Pendlebury S, Wong A, Alladi S, et al
    Tackling challenges in care of Alzheimer's disease and other dementias amid the COVID-19 pandemic, now and in the future.
    Alzheimers Dement. 2020 Aug 12. doi: 10.1002/alz.12143.
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  326. JIA L, Zhu M, Kong C, Pang Y, et al
    Blood neuro-exosomal synaptic proteins predict Alzheimer's disease at the asymptomatic stage.
    Alzheimers Dement. 2020 Aug 10. doi: 10.1002/alz.12166.
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  327. NHO K, Nudelman K, Allen M, Hodges A, et al
    Genome-wide transcriptome analysis identifies novel dysregulated genes implicated in Alzheimer's pathology.
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    July 2020
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    Dietary fatty acids and risk of Alzheimer's disease and related dementias: Observations from the Washington Heights-Hamilton Heights-Inwood Columbia Aging Project (WHICAP).
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    A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer's disease: Primary results of the AMBAR Study.
    Alzheimers Dement. 2020 Jul 27. doi: 10.1002/alz.12137.
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  330. VIDONI ED, Choi IY, Lee P, Reed G, et al
    Safety and target engagement profile of two oxaloacetate doses in Alzheimer's patients.
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    Circulating ethanolamine plasmalogen indices in Alzheimer's disease: Relation to diagnosis, cognition, and CSF tau.
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    June 2020
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    An agnostic reevaluation of the amyloid cascade hypothesis of Alzheimer's disease pathogenesis: The role of APP homeostasis.
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  334. LUTZ MW, Luo S, Williamson DE, Chiba-Falek O, et al
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  335. EREN E, Hunt JFV, Shardell M, Chawla S, et al
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  336. New Thinking About Thinking, Part 3. Advice on preparing a successful manuscript for Alzheimer's & Dementia.
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  338. SHERVA R, Gross A, Mukherjee S, Koesterer R, et al
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  340. SNYDER HM, Bain LJ, Brickman AM, Carrillo MC, et al
    Further understanding the connection between Alzheimer's disease and Down syndrome.
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    Exploratory analysis of mtDNA haplogroups in two Alzheimer's longitudinal cohorts.
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    GABAergic dysfunction in excitatory and inhibitory (E/I) imbalance drives the pathogenesis of Alzheimer's disease.
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  345. GENTREAU M, Chuy V, Feart C, Samieri C, et al
    Refined carbohydrate-rich diet is associated with long-term risk of dementia and Alzheimer's disease in apolipoprotein E epsilon4 allele carriers.
    Alzheimers Dement. 2020 Jun 7. doi: 10.1002/alz.12114.
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    Sequences of cognitive decline in typical Alzheimer's disease and posterior cortical atrophy estimated using a novel event-based model of disease progression.
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    May 2020
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    Cancer and risk of Alzheimer's disease: Small association in a nationwide cohort study.
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    Scientific Advising and Reviewing: On strengthening the bond between the Alzheimer's Association and the scientific community.
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    Baseline demographic, clinical, and cognitive characteristics of the Alzheimer's Prevention Initiative (API) Autosomal-Dominant Alzheimer's Disease Colombia Trial.
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  350. MECCA AP, Chen MK, O'Dell RS, Naganawa M, et al
    In vivo measurement of widespread synaptic loss in Alzheimer's disease with SV2A PET.
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  351. MOORE EE, Gifford KA, Khan OA, Liu D, et al
    Cerebrospinal fluid biomarkers of neurodegeneration, synaptic dysfunction, and axonal injury relate to atrophy in structural brain regions specific to Alzheimer's disease.
    Alzheimers Dement. 2020 May 6. doi: 10.1002/alz.12087.
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  352. RENTZ DM, Wessels AM, Bain LJ, Weber CJ, et al
    Clinical meaningfulness addressed at Alzheimer's Association Research Roundtable.
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    April 2020
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    Age-stratified longitudinal study of Alzheimer's and vascular dementia patients.
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    Contribution of mixed pathology to medial temporal lobe atrophy in Alzheimer's disease.
    Alzheimers Dement. 2020 Apr 22. doi: 10.1002/alz.12079.
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  355. MURAOKA S, DeLeo AM, Sethi MK, Yukawa-Takamatsu K, et al
    Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues.
    Alzheimers Dement. 2020 Apr 17. doi: 10.1002/alz.12089.
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  356. TRARES K, Gao X, Perna L, Rujescu D, et al
    Associations of urinary 8-iso-prostaglandin F2alpha levels with all-cause dementia, Alzheimer's disease, and vascular dementia incidence: results from a prospective cohort study.
    Alzheimers Dement. 2020 Apr 12. doi: 10.1002/alz.12081.
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  357. LOPES ALVES I, Collij LE, Altomare D, Frisoni GB, et al
    Quantitative amyloid PET in Alzheimer's disease: the AMYPAD prognostic and natural history study.
    Alzheimers Dement. 2020 Apr 12. doi: 10.1002/alz.12069.
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    Initiation of symptomatic medication in Alzheimer's disease clinical trials: Hypothetical versus treatment policy approach.
    Alzheimers Dement. 2020 Apr 8. doi: 10.1002/alz.12058.
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    Learning from amyloid trials in Alzheimer's disease. A virtual patient analysis using a quantitative systems pharmacology approach.
    Alzheimers Dement. 2020 Apr 7. doi: 10.1002/alz.12082.
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  360. CABALLERO MAA, Song Z, Rubinski A, Duering M, et al
    Age-dependent amyloid deposition is associated with white matter alterations in cognitively normal adults during the adult life span.
    Alzheimers Dement. 2020;16:651-661.
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    March 2020

  361. Alzheimer's Disease Research Enterprise in the Era of COVID-19/SARS-CoV-2.
    Alzheimers Dement. 2020 Mar 22. doi: 10.1002/alz.12093.

  362. 2020 Alzheimer's disease facts and figures.
    Alzheimers Dement. 2020 Mar 10. doi: 10.1002/alz.12068.
    PubMed     Abstract available

  363. JANSSEN O, Vos SJB, Garcia-Negredo G, Tochel C, et al
    Real-world evidence in Alzheimer's disease: The ROADMAP Data Cube.
    Alzheimers Dement. 2020;16:461-471.
    PubMed     Abstract available

  364. LOWE VJ, Lundt ES, Albertson SM, Min HK, et al
    Tau-positron emission tomography correlates with neuropathology findings.
    Alzheimers Dement. 2020;16:561-571.
    PubMed     Abstract available

  365. PAPP KV, Buckley R, Mormino E, Maruff P, et al
    Clinical meaningfulness of subtle cognitive decline on longitudinal testing in preclinical AD.
    Alzheimers Dement. 2020;16:552-560.
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    February 2020
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    Complex interactions underlie racial disparity in the risk of developing Alzheimer's disease dementia.
    Alzheimers Dement. 2020 Feb 17. doi: 10.1002/alz.12060.
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  367. SCHAFFERT J, LoBue C, White CL 3rd, Wilmoth K, et al
    Risk factors for earlier dementia onset in autopsy-confirmed Alzheimer's disease, mixed Alzheimer's with Lewy bodies, and pure Lewy body disease.
    Alzheimers Dement. 2020 Feb 11. doi: 10.1002/alz.12049.
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  368. FRANZMEIER N, Koutsouleris N, Benzinger T, Goate A, et al
    Predicting sporadic Alzheimer's disease progression via inherited Alzheimer's disease-informed machine-learning.
    Alzheimers Dement. 2020 Feb 11. doi: 10.1002/alz.12032.
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  369. Bill Gates funds $10 million grant to Alzheimer's Association to fuel research for Alzheimer's treatment.
    Alzheimers Dement. 2020;16:384.

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    Synaptic, axonal damage and inflammatory cerebrospinal fluid biomarkers in neurodegenerative dementias.
    Alzheimers Dement. 2020;16:262-272.
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    Amyloid pathology-produced unexpected modifications of calcium homeostasis in hippocampal subicular dendrites.
    Alzheimers Dement. 2020;16:251-261.
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    January 2020
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    Polysomnographic assessment of suvorexant in patients with probable Alzheimer's disease dementia and insomnia: a randomized trial.
    Alzheimers Dement. 2020 Jan 15. doi: 10.1002/alz.12035.
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  373. JIA L, Fu Y, Shen L, Zhang H, et al
    PSEN1, PSEN2, and APP mutations in 404 Chinese pedigrees with familial Alzheimer's disease.
    Alzheimers Dement. 2020;16:178-191.
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  374. SNYDER PJ, Snyder HM, Bain LJ
    Retinal imaging think tank convened by the Alzheimer's Association to examine its promise in the early detection of Alzheimer's.
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    Developing retinal biomarkers for the earliest stages of Alzheimer's disease: What we know, what we don't, and how to move forward.
    Alzheimers Dement. 2020;16:229-243.
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    Two-stage Bayesian GWAS of 9576 individuals identifies SNP regions that are targeted by miRNAs inversely expressed in Alzheimer's and cancer.
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    Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN).
    Alzheimers Dement. 2020;16:219-228.
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  378. LINARD M, Letenneur L, Garrigue I, Doize A, et al
    Interaction between APOE4 and herpes simplex virus type 1 in Alzheimer's disease.
    Alzheimers Dement. 2020;16:200-208.
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    Concordance of Lumipulse cerebrospinal fluid t-tau/Abeta42 ratio with amyloid PET status.
    Alzheimers Dement. 2020;16:144-152.
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    December 2019
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    Plasma biomarkers of astrocytic and neuronal dysfunction in early- and late-onset Alzheimer's disease.
    Alzheimers Dement. 2019 Dec 23. pii: S1552-5260(19)35373.
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  381. SABBAGH M, Sadowsky C, Tousi B, Agronin ME, et al
    Effects of a combined transcranial magnetic stimulation (TMS) and cognitive training intervention in patients with Alzheimer's disease.
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    November 2019
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  383. ANDREWS SJ, Goate A, Anstey KJ
    Association between alcohol consumption and Alzheimer's disease: A Mendelian randomization study.
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  384. GONZALEZ HM, Tarraf W, Fornage M, Gonzalez KA, et al
    A research framework for cognitive aging and Alzheimer's disease among diverse US Latinos: Design and implementation of the Hispanic Community Health Study/Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA).
    Alzheimers Dement. 2019 Nov 20. pii: S1552-5260(19)35362.
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  385. TOLAR M, Abushakra S, Sabbagh M
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    Alzheimers Dement. 2019 Nov 4. pii: S1552-5260(19)35450.
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    October 2019
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    Individualized clinical management of patients at risk for Alzheimer's dementia.
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    C99 selectively accumulates in vulnerable neurons in Alzheimer's disease.
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    Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study.
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    Prediction of Alzheimer's disease diagnosis within 14 years through Abeta misfolding in blood plasma compared to APOE4 status, and other risk factors.
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    Association between enrollment factors and incident cognitive impairment in Blacks and Whites: Data from the Alzheimer's Disease Center.
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    Current and past leisure time physical activity in relation to risk of Alzheimer's disease in older adults.
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    Escitalopram for agitation in Alzheimer's disease (S-CitAD): Methods and design of an investigator-initiated, randomized, controlled, multicenter clinical trial.
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    September 2019
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    Local ancestry at APOE modifies Alzheimer's disease risk in Caribbean Hispanics.
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    Differences in service utilization at an urban tribal health organization before and after Alzheimer's disease or related dementia diagnosis: A cohort study.
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    August 2019
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    Do Alzheimer's and Lewy body disease have discrete pathological signatures of gait?
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