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Alzheimer's Disease

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Articles published in Alzheimers Dement
Retrieve available abstracts of 1268 articles:
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Single Articles

December 2024

CHEON J, Kwon S, Kim M
Exerkines mitigating Alzheimer's disease progression by regulating inflammation: Focusing on macrophage/microglial NLRP3 inflammasome pathway.
Alzheimers Dement. 2024 Dec 6. doi: 10.1002/alz.14432.
PubMed Abstract available

WU Y, Libby JB, Dumitrescu LC, De Jager PL, et al
Association of ten VEGF family genes with Alzheimer's disease endophenotypes at single cell resolution.
Alzheimers Dement. 2024 Dec 6. doi: 10.1002/alz.14419.
PubMed Abstract available

CHEN K, Weng Y, Huang Y, Zhang Y, et al
A multi-view learning approach with diffusion model to synthesize FDG PET from MRI T1WI for diagnosis of Alzheimer's disease.
Alzheimers Dement. 2024 Dec 6. doi: 10.1002/alz.14421.
PubMed Abstract available

XU J, Song W, Xu Z, Danziger MM, et al
Single-microglia transcriptomic transition network-based prediction and real-world patient data validation identifies ketorolac as a repurposable drug for Alzheimer's disease.
Alzheimers Dement. 2024 Dec 6. doi: 10.1002/alz.14373.
PubMed Abstract available

TEUNISSEN CE, Kolster R, Triana-Baltzer G, Janelidze S, et al
Plasma p-tau immunoassays in clinical research for Alzheimer's disease.
Alzheimers Dement. 2024 Dec 3. doi: 10.1002/alz.14397.
PubMed Abstract available

TAGHVAEI M, Dolui S, Sadaghiani S, Shakibajahromi B, et al
Regional cerebral blood flow reflects both neurodegeneration and microvascular integrity across the Alzheimer's continuum.
Alzheimers Dement. 2024 Dec 3. doi: 10.1002/alz.14382.
PubMed Abstract available

November 2024

KOOPS EA, Dutta J, Hanseeuw BJ, Becker JA, et al
Elevated locus coeruleus metabolism provides resilience against cognitive decline in preclinical Alzheimer's disease.
Alzheimers Dement. 2024 Nov 26. doi: 10.1002/alz.14385.
PubMed Abstract available

ROUSSET RZ, den Braber A, Verberk IMW, Boonkamp L, et al
Heritability of Alzheimer's disease plasma biomarkers: A nuclear twin family design.
Alzheimers Dement. 2024 Nov 26. doi: 10.1002/alz.14269.
PubMed Abstract available

SAVELEVA L, Cervena T, Mengoni C, Sima M, et al
Transcriptomic and epigenomic profiling reveals altered responses to diesel emissions in Alzheimer's disease both in vitro and in population-based data.
Alzheimers Dement. 2024 Nov 23. doi: 10.1002/alz.14347.
PubMed Abstract available

IBANEZ L, Liu M, Beric A, Timsina J, et al
Benchmarking of a multi-biomarker low-volume panel for Alzheimer's disease and related dementia research.
Alzheimers Dement. 2024 Nov 22. doi: 10.1002/alz.14413.
PubMed Abstract available

DEVANARAYAN V, Charil A, Horie K, Doherty T, et al
Plasma pTau217 ratio predicts continuous regional brain tau accumulation in amyloid-positive early Alzheimer's disease.
Alzheimers Dement. 2024 Nov 22. doi: 10.1002/alz.14411.
PubMed Abstract available

MARES J, Kumar G, Sharma A, Emrani S, et al
APOE epsilon4-associated heterogeneity of neuroimaging biomarkers across the Alzheimer's disease continuum.
Alzheimers Dement. 2024 Nov 22. doi: 10.1002/alz.14392.
PubMed Abstract available

LU X, Zhang Y, Tang Y, Bernick C, et al
Conversion to Alzheimer's disease dementia from normal cognition directly or with the intermediate mild cognitive impairment stage.
Alzheimers Dement. 2024 Nov 19. doi: 10.1002/alz.14393.
PubMed Abstract available

REA REYES RE, Cody KA, Wilson RE, Zetterberg H, et al
Visual read of [F-18]florquinitau PET that includes and extends beyond the mesial temporal lobe is associated with increased plasma pTau217 and cognitive decline in a cohort that is enriched with risk for Alzheimer's disease.
Alzheimers Dement. 2024 Nov 19. doi: 10.1002/alz.14406.
PubMed Abstract available

LANDAU SM, Harrison TM, Baker SL, Boswell MS, et al
Positron emission tomography harmonization in the Alzheimer's Disease Neuroimaging Initiative: A scalable and rigorous approach to multisite amyloid and tau quantification.
Alzheimers Dement. 2024 Nov 19. doi: 10.1002/alz.14378.
PubMed Abstract available

PERRY J, Radenbach K, Geschke K, Rostamzadeh A, et al
Counseling and disclosure practices in predictive Alzheimer's disease diagnostics: A scoping review.
Alzheimers Dement. 2024 Nov 19. doi: 10.1002/alz.14365.
PubMed Abstract available

HUHE H, Shapley SM, Duong DM, Wu F, et al
Marmosets as model systems for the study of Alzheimer's disease and related dementias: Substantiation of physiological tau 3R and 4R isoform expression and phosphorylation.
Alzheimers Dement. 2024 Nov 19. doi: 10.1002/alz.14366.
PubMed Abstract available

GOSCHEL L, Dell'Orco A, Fillmer A, Aydin S, et al
Plasma p-tau181 and GFAP reflect 7T MR-derived changes in Alzheimer's disease: A longitudinal study of structural and functional MRI and MRS.
Alzheimers Dement. 2024 Nov 19. doi: 10.1002/alz.14318.
PubMed Abstract available

PETERSEN ME, Flores-Aguilar L, Head E, Montoliu-Gaya L, et al
Blood biomarkers in Down syndrome: Facilitating Alzheimer's disease detection and monitoring.
Alzheimers Dement. 2024 Nov 13. doi: 10.1002/alz.14364.
PubMed Abstract available

CHEN Y, Qi Y, Hu Y, Qiu X, et al
Integrated cerebellar radiomic-network model for predicting mild cognitive impairment in Alzheimer's disease.
Alzheimers Dement. 2024 Nov 13. doi: 10.1002/alz.14361.
PubMed Abstract available

SEIFAR F, Fox EJ, Shantaraman A, Liu Y, et al
Large-scale deep proteomic analysis in Alzheimer's disease brain regions across race and ethnicity.
Alzheimers Dement. 2024 Nov 13. doi: 10.1002/alz.14360.
PubMed Abstract available

LEE EH, Kang SH, Shin D, Kim YJ, et al
Plasma Alzheimer's disease biomarker variability: Amyloid-independent and amyloid-dependent factors.
Alzheimers Dement. 2024 Nov 13. doi: 10.1002/alz.14368.
PubMed Abstract available

AISEN P, Bateman RJ, Crowther D, Cummings J, et al
The case for regulatory approval of amyloid-lowering immunotherapies in Alzheimer's disease based on clearcut biomarker evidence.
Alzheimers Dement. 2024 Nov 13. doi: 10.1002/alz.14342.
PubMed Abstract available

SCHAUER SP, Toth B, Lee J, Honigberg LA, et al
Pharmacodynamic effects of semorinemab on plasma and CSF biomarkers of Alzheimer's disease pathophysiology.
Alzheimers Dement. 2024 Nov 8. doi: 10.1002/alz.14346.
PubMed Abstract available

AMAZA H, Niay A, Thao MS, Strong J, et al
The Health Equity Scholars Program: Fostering Culturally Competent and Successful Independent Investigators in Alzheimer's Disease and Related Dementia Research.
Alzheimers Dement. 2024 Nov 7. doi: 10.1002/alz.14323.
PubMed Abstract available

NGAI T, Willett J, Waqas M, Fishbein LH, et al
Assessing polyomic risk to predict Alzheimer's disease using a machine learning model.
Alzheimers Dement. 2024 Nov 7. doi: 10.1002/alz.14319.
PubMed Abstract available

Alzheimer's Association workgroup suggests language for clinicians to talk to their patients about new treatments.
Alzheimers Dement. 2024;20:8225-8226.
PubMed

DHANA K, Barnes LL, Beck T, Dhana A, et al
External validation of dementia prediction models in Black or African American and White older adults: A longitudinal population-based study in the United States.
Alzheimers Dement. 2024;20:7913-7922.
PubMed Abstract available

SCHWARZ CG, Choe M, Rossi S, Das SR, et al
Implementation and validation of face de-identification (de-facing) in ADNI4.
Alzheimers Dement. 2024;20:8048-8061.
PubMed Abstract available

LOWE VJ, Mester CT, Lundt ES, Lee J, et al
Amyloid PET detects the deposition of brain Abeta earlier than CSF fluid biomarkers.
Alzheimers Dement. 2024;20:8097-8112.
PubMed Abstract available

MAIN LR, Song YE, Lynn A, Laux RA, et al
Genetic analysis of cognitive preservation in the midwestern Amish reveals a novel locus on chromosome 2.
Alzheimers Dement. 2024;20:7453-7464.
PubMed Abstract available

POWELL KR, Isnainy M, Amewudah P, Paez-Perez D, et al
Untangling the complex web of avoidable nursing home-to-hospital transfers of residents with dementia.
Alzheimers Dement. 2024;20:8038-8047.
PubMed Abstract available

POTTER WZ, Buckholtz NS, Paul SM
The origins of ADNI.
Alzheimers Dement. 2024;20:8188-8191.
PubMed Abstract available

IORDAN AD, Ploutz-Snyder R, Ghosh B, Rahman-Filipiak A, et al
Salience network segregation mediates the effect of tau pathology on mild behavioral impairment.
Alzheimers Dement. 2024;20:7675-7685.
PubMed Abstract available

ROSTAMZADEH A, Kalthegener F, Schwegler C, Romotzky V, et al
Psychological outcomes of dementia risk estimation in MCI patients: Results from the PreDADQoL project.
Alzheimers Dement. 2024;20:7635-7656.
PubMed Abstract available

TATE M, Wijeratne HRS, Kim B, Philtjens S, et al
Deletion of miR-33, a regulator of the ABCA1-APOE pathway, ameliorates neuropathological phenotypes in APP/PS1 mice.
Alzheimers Dement. 2024;20:7805-7818.
PubMed Abstract available

YAO W, Hou X, Zhou H, You S, et al
Associations between the multitrajectory neuroplasticity of neuronavigated rTMS-mediated angular gyrus networks and brain gene expression in AD spectrum patients with sleep disorders.
Alzheimers Dement. 2024;20:7885-7901.
PubMed Abstract available

MILLER AA, Sharp ES, Wang S, Zhao Y, et al
Self-reported hearing loss is associated with faster cognitive and functional decline but not diagnostic conversion in the ADNI cohort.
Alzheimers Dement. 2024;20:7847-7858.
PubMed Abstract available

JANG H, Chun MY, Yun J, Kim JP, et al
Ethnic differences in the prevalence of amyloid positivity and cognitive trajectories.
Alzheimers Dement. 2024;20:7556-7566.
PubMed Abstract available

ZHONG R, Xu Y, Williams JW, Li L, et al
Loss of TREM2 diminishes CAA despite an overall increase of amyloid load in Tg-SwDI mice.
Alzheimers Dement. 2024;20:7595-7612.
PubMed Abstract available

KRUGER DM, Pena-Centeno T, Liu S, Park T, et al
The plasma miRNAome in ADNI: Signatures to aid the detection of at-risk individuals.
Alzheimers Dement. 2024;20:7479-7494.
PubMed Abstract available

YUSHKEVICH PA, Ittyerah R, Li Y, Denning AE, et al
Morphometry of medial temporal lobe subregions using high-resolution T2-weighted MRI in ADNI3: Why, how, and what's next?
Alzheimers Dement. 2024;20:8113-8128.
PubMed Abstract available

LIU T, Wang M, Zhang J, Ye C, et al
Brain network dynamics in patients with single- and multiple-domain amnestic mild cognitive impairment.
Alzheimers Dement. 2024;20:7657-7674.
PubMed Abstract available

GIBSON AW, Elser H, Rosso M, Cornblath EJ, et al
Ischemic stroke associated with amyloid-related imaging abnormalities in a patient treated with lecanemab.
Alzheimers Dement. 2024;20:8192-8197.
PubMed Abstract available

October 2024

MOTOLESE F, Dubbioso R, Ranieri F, Lazzaro VD, et al
Neurophysiological biomarkers of Alzheimer's disease: In vivo evaluation of synaptic dysfunction.
Alzheimers Dement. 2024 Oct 29. doi: 10.1002/alz.14341.
PubMed

MOSCOSO A, Villain N
2024 AA criteria for Alzheimer's disease diagnosis: Mainly anchored at Abeta not tau.
Alzheimers Dement. 2024 Oct 29. doi: 10.1002/alz.14340.
PubMed

TERSTEGE DJ, Galea LAM, Epp JR
Retrosplenial hypometabolism precedes the conversion from mild cognitive impairment to Alzheimer's disease.
Alzheimers Dement. 2024 Oct 29. doi: 10.1002/alz.14258.
PubMed Abstract available

ESCAMILLA S, Badillos R, Comella JX, Sole M, et al
Synaptic and extrasynaptic distribution of NMDA receptors in the cortex of Alzheimer's disease patients.
Alzheimers Dement. 2024 Oct 25. doi: 10.1002/alz.14125.
PubMed Abstract available

WANG W, Wang Q, Qi X, Gurney M, et al
Associations of semaglutide with first-time diagnosis of Alzheimer's disease in patients with type 2 diabetes: Target trial emulation using nationwide real-world data in the US.
Alzheimers Dement. 2024 Oct 24. doi: 10.1002/alz.14313.
PubMed Abstract available

GABRIELLI AP, Novikova L, Ranjan A, Wang X, et al
Inhibiting mtDNA transcript translation alters Alzheimer's disease-associated biology.
Alzheimers Dement. 2024 Oct 23. doi: 10.1002/alz.14275.
PubMed Abstract available

ROSEWOOD TJ, Nho K, Risacher SL, Liu S, et al
Pathway enrichment in genome-wide analysis of longitudinal Alzheimer's disease biomarker endophenotypes.
Alzheimers Dement. 2024 Oct 23. doi: 10.1002/alz.14308.
PubMed Abstract available

RIVERA MINDT M, Arentoft A, Calcetas AT, Guzman VA, et al
The Alzheimer's Disease Neuroimaging Initiative-4 (ADNI-4) Engagement Core: A culturally informed, community-engaged research (CI-CER) model to advance brain health equity.
Alzheimers Dement. 2024 Oct 23. doi: 10.1002/alz.14242.
PubMed Abstract available

XU L, Zhao Y, Choi S, Li M, et al
Reductions in the white-gray functional connectome in preclinical Alzheimer's disease and their associations with amyloid and cognition.
Alzheimers Dement. 2024 Oct 23. doi: 10.1002/alz.14334.
PubMed Abstract available

MCLAUGHLIN J, Scotton WJ, Ryan NS, Hardy JA, et al
Assessing clinical progression measures in Alzheimer's disease trials: A systematic review and meta-analysis.
Alzheimers Dement. 2024 Oct 22. doi: 10.1002/alz.14314.
PubMed Abstract available

BATRA R, Krumsiek J, Wang X, Allen M, et al
Comparative brain metabolomics reveals shared and distinct metabolic alterations in Alzheimer's disease and progressive supranuclear palsy.
Alzheimers Dement. 2024 Oct 22. doi: 10.1002/alz.14249.
PubMed Abstract available

THROPP P, Phillips E, Jung Y, Thomas DL, et al
Arterial spin labeling perfusion MRI in the Alzheimer's Disease Neuroimaging Initiative: Past, present, and future.
Alzheimers Dement. 2024 Oct 21. doi: 10.1002/alz.14310.
PubMed Abstract available

SCHAAP T, Thropp P, Tosun D
Timing of Alzheimer's disease biomarker progressions: A two-decade observational study from the Alzheimer's Disease Neuroimaging Initiative (ADNI).
Alzheimers Dement. 2024 Oct 21. doi: 10.1002/alz.14306.
PubMed Abstract available

ANDREWS SJ, Boeriu AI, Belloy ME, Renton AE, et al
Dementia risk scores, apolipoprotein E, and risk of Alzheimer's disease: One size does not fit all.
Alzheimers Dement. 2024 Oct 21. doi: 10.1002/alz.14300.
PubMed Abstract available

LEE WP, Choi SH, Shea MG, Cheng PL, et al
Association of common and rare variants with Alzheimer's disease in more than 13,000 diverse individuals with whole-genome sequencing from the Alzheimer's Disease Sequencing Project.
Alzheimers Dement. 2024 Oct 20. doi: 10.1002/alz.14283.
PubMed Abstract available

TOSUN D, Hausle Z, Thropp P, Concha-Marambio L, et al
Association of CSF alpha-synuclein seed amplification assay positivity with disease progression and cognitive decline: A longitudinal Alzheimer's Disease Neuroimaging Initiative study.
Alzheimers Dement. 2024 Oct 20. doi: 10.1002/alz.14276.
PubMed Abstract available

KANG M, Farrell JJ, Zhu C, Park H, et al
Whole-genome sequencing study in Koreans identifies novel loci for Alzheimer's disease.
Alzheimers Dement. 2024 Oct 20. doi: 10.1002/alz.14128.
PubMed Abstract available

JONES AA, Ramos-Miguel A, Gicas KM, Petyuk VA, et al
A multilayer network analysis of Alzheimer's disease pathogenesis: Roles for p-tau, synaptic peptides, and physical activity.
Alzheimers Dement. 2024 Oct 12. doi: 10.1002/alz.14286.
PubMed Abstract available

SCHINDLER SE, Petersen KK, Saef B, Tosun D, et al
Head-to-head comparison of leading blood tests for Alzheimer's disease pathology.
Alzheimers Dement. 2024 Oct 12. doi: 10.1002/alz.14315.
PubMed Abstract available

MADSEN LS, Ismail R, Parbo P, Kjeldsen PL, et al
Microglial responses partially mediate the effect of Abeta on cognition in Alzheimer's disease.
Alzheimers Dement. 2024 Oct 11. doi: 10.1002/alz.14298.
PubMed Abstract available

SANDOVAL C, Lee J, Toth B, Nagaraj R, et al
CSF complement proteins are elevated in prodromal to moderate Alzheimer's disease patients and are not altered by the anti-tau antibody semorinemab.
Alzheimers Dement. 2024 Oct 6. doi: 10.1002/alz.14271.
PubMed Abstract available

MIELKE MM, Anderson M, Ashford JW, Jeromin A, et al
Considerations for widespread implementation of blood-based biomarkers of Alzheimer's disease.
Alzheimers Dement. 2024 Oct 6. doi: 10.1002/alz.14150.
PubMed Abstract available

CUSTODIO N, Allegri R, Lopera F, Caramelli P, et al
Need to adapt Alzheimer's disease criteria in Latin America.
Alzheimers Dement. 2024 Oct 6. doi: 10.1002/alz.14289.
PubMed

NAKAMURA Y, Adachi J, Hirota N, Iba K, et al
Brexpiprazole treatment for agitation in Alzheimer's dementia: A randomized study.
Alzheimers Dement. 2024 Oct 6. doi: 10.1002/alz.14282.
PubMed Abstract available

CUBAS GUILLEN JF, Chrem Mendez P, Surace E, Martin ME, et al
Argentina-Alzheimer's Disease Neuroimaging Initiative: pioneering Alzheimer's Research in Latin America and its Implications for Regional Advancement.
Alzheimers Dement. 2024 Oct 6. doi: 10.1002/alz.14285.
PubMed Abstract available

AGGIDIS A, Devitt G, Zhang Y, Chatterjee S, et al
A novel peptide-based tau aggregation inhibitor as a potential therapeutic for Alzheimer's disease and other tauopathies.
Alzheimers Dement. 2024 Oct 3. doi: 10.1002/alz.14246.
PubMed Abstract available

FENG Y, Yang X, Hou Y, Zhou Y, et al
Widespread transposable element dysregulation in human aging brains with Alzheimer's disease.
Alzheimers Dement. 2024 Oct 2. doi: 10.1002/alz.14164.
PubMed Abstract available

PERRIN RJ, Franklin EE, Bernhardt H, Burns A, et al
The Alzheimer's Disease Neuroimaging Initiative Neuropathology Core: An update.
Alzheimers Dement. 2024 Oct 1. doi: 10.1002/alz.14253.
PubMed Abstract available

MIELKE MM, Anderson M, Ashford JW, Jeromin A, et al
Recommendations for clinical implementation of blood-based biomarkers for Alzheimer's disease.
Alzheimers Dement. 2024 Oct 1. doi: 10.1002/alz.14184.
PubMed Abstract available

AAIC 2024 previewed the future of Alzheimer's and dementia prevention, care, and treatment.
Alzheimers Dement. 2024;20:7427-7431.
PubMed

BRUNO D, Jauregi-Zinkunegi A, Bock JR
Predicting CDR status over 36 months with a recall-based digital cognitive biomarker.
Alzheimers Dement. 2024;20:7274-7280.
PubMed Abstract available

JACK CR JR, Arani A, Borowski BJ, Cash DM, et al
Overview of ADNI MRI.
Alzheimers Dement. 2024;20:7350-7360.
PubMed Abstract available

HOWE MD, Caruso MR, Manoochehri M, Kunicki ZJ, et al
Utility of cerebrovascular imaging biomarkers to detect cerebral amyloidosis.
Alzheimers Dement. 2024;20:7220-7231.
PubMed Abstract available

MILLER MJ, Diaz A, Conti C, Albala B, et al
The ADNI4 Digital Study: A novel approach to recruitment, screening, and assessment of participants for AD clinical research.
Alzheimers Dement. 2024;20:7232-7247.
PubMed Abstract available

DA SILVA CORREIA A, Schmitz M, Fischer AL, da Silva Correia S, et al
Cellular prion protein acts as mediator of amyloid beta uptake by caveolin-1 causing cellular dysfunctions in vitro and in vivo.
Alzheimers Dement. 2024;20:6776-6792.
PubMed Abstract available

SALAZAR CR, Tallakson M, Corona MG, Duran E, et al
Community recruitment of underrepresented populations to the AHEAD 3-45 preclinical AD trial using novel partnerships with nursing and community-based organizations: Lessons and outcomes.
Alzheimers Dement. 2024;20:7160-7173.
PubMed Abstract available

KOETSIER J, Cavill R, Reijnders R, Harvey J, et al
Blood-based multivariate methylation risk score for cognitive impairment and dementia.
Alzheimers Dement. 2024;20:6682-6698.
PubMed Abstract available

ABU-RUMEILEH S, Arajyan G, Reiman EM, Otto M, et al
Contribution of alpha-synuclein pathology to cerebral glucose metabolism in patients with amnestic MCI.
Alzheimers Dement. 2024;20:7411-7419.
PubMed Abstract available

YAO J, Li Z, Zhou Z, Bao A, et al
Distinct regional vulnerability to Abeta and iron accumulation in post mortem AD brains.
Alzheimers Dement. 2024;20:6984-6997.
PubMed Abstract available

BYNUM JPW, Benloucif S, Martindale J, O'Malley AJ, et al
Regional variation in diagnostic intensity of dementia among older U.S. adults: An observational study.
Alzheimers Dement. 2024;20:6755-6764.
PubMed Abstract available

BECKETT LA, Saito N, Donohue MC, Harvey DJ, et al
Contributions of the ADNI Biostatistics Core.
Alzheimers Dement. 2024;20:7331-7339.
PubMed Abstract available

TOGA AW, Neu S, Sheehan ST, Crawford K, et al
The informatics of ADNI.
Alzheimers Dement. 2024;20:7320-7330.
PubMed Abstract available

STRADFORD J, Heyworth NC, Jackson M, Norman M, et al
Increasing research study engagement in minoritized populations: An example from the Black Women Inflammation and Tau Study.
Alzheimers Dement. 2024;20:7403-7410.
PubMed Abstract available

HARVEY DJ, Tosun D, Jack CR Jr, Weiner M, et al
Standardized statistical framework for comparison of biomarkers: Techniques from ADNI.
Alzheimers Dement. 2024;20:6834-6843.
PubMed Abstract available

JAGUST WJ, Koeppe RA, Rabinovici GD, Villemagne VL, et al
The ADNI PET Core at 20.
Alzheimers Dement. 2024;20:7340-7349.
PubMed Abstract available

September 2024

SEWELL KR, Doecke JD, Xiong C, Benzinger T, et al
Longitudinal associations between exercise and biomarkers in autosomal dominant Alzheimer's disease.
Alzheimers Dement. 2024 Sep 26. doi: 10.1002/alz.14270.
PubMed Abstract available

WANG L, Bi L, Qiu Y, Huang G, et al
Effectiveness of electro-acupuncture for cognitive improvement on Alzheimer's disease quantified via PET imaging of sphingosine-1-phosphate receptor 1.
Alzheimers Dement. 2024 Sep 25. doi: 10.1002/alz.14260.
PubMed Abstract available

TARIOT PN, Riviere ME, Salloway S, Burns JM, et al
Reversibility of cognitive worsening observed with BACE inhibitor umibecestat in the Alzheimer's Prevention Initiative (API) Generation Studies.
Alzheimers Dement. 2024 Sep 25. doi: 10.1002/alz.14237.
PubMed Abstract available

LLOYD C, Freskgard PO, Newton P, Lowne D, et al
MEDI1814 selectively reduces free Abeta42 in cerebrospinal fluid of non-clinical species and Alzheimer's disease patients.
Alzheimers Dement. 2024 Sep 25. doi: 10.1002/alz.14238.
PubMed Abstract available

YANG K, Yang X, Yin P, Zhou M, et al
Temporal trend and attributable risk factors of Alzheimer's disease and other dementias burden in China: Findings from the Global Burden of Disease Study 2021.
Alzheimers Dement. 2024 Sep 23. doi: 10.1002/alz.14254.
PubMed Abstract available

THOMAS KR, Bangen KJ, Rotblatt LJ, Weigand AJ, et al
Self- and study partner-reported cognitive decline in older adults without dementia: The role of alpha-synuclein and amyloid biomarkers in the Alzheimer's Disease Neuroimaging Initiative.
Alzheimers Dement. 2024 Sep 23. doi: 10.1002/alz.14239.
PubMed Abstract available

LEUZY A, Heeman F, Bosch I, Lener F, et al
REAL AD-Validation of a realistic screening approach for early Alzheimer's disease.
Alzheimers Dement. 2024 Sep 23. doi: 10.1002/alz.14219.
PubMed Abstract available

RENTZ DM, Aisen PS, Atri A, Hitchcock J, et al
Benefits and risks of FDA-approved amyloid-targeting antibodies for treatment of early Alzheimer's disease: Navigating clinician-patient engagement.
Alzheimers Dement. 2024 Sep 22. doi: 10.1002/alz.14199.
PubMed Abstract available

LIU S, Park T, Kruger DM, Pena-Centeno T, et al
Plasma miRNAs across the Alzheimer's disease continuum: Relationship to central biomarkers.
Alzheimers Dement. 2024 Sep 18. doi: 10.1002/alz.14230.
PubMed Abstract available

LU J, Wang J, Wu J, Zhang H, et al
Pilot implementation of the revised criteria for staging of Alzheimer's disease by the Alzheimer's Association Workgroup in a tertiary memory clinic.
Alzheimers Dement. 2024 Sep 17. doi: 10.1002/alz.14245.
PubMed Abstract available

HE B, Wu R, Sangani N, Pugalenthi PV, et al
Integrating amyloid imaging and genetics for early risk stratification of Alzheimer's disease.
Alzheimers Dement. 2024 Sep 17. doi: 10.1002/alz.14244.
PubMed Abstract available

DILCHER R, Wall S, Gross M, Katzdobler S, et al
Combining cerebrospinal fluid and PI-2620 tau-PET for biomarker-based stratification of Alzheimer's disease and 4R-tauopathies.
Alzheimers Dement. 2024 Sep 12. doi: 10.1002/alz.14185.
PubMed Abstract available

O'NEILL N, Stein TD, Olayinka OA, Empawi JA, et al
Cognitive resilience to Alzheimer's disease characterized by cell-type abundance.
Alzheimers Dement. 2024 Sep 11. doi: 10.1002/alz.14187.
PubMed Abstract available

SONI ND, Swain A, Juul H, Cao Q, et al
Detection of sex-specific glutamate changes in subregions of hippocampus in an early-stage Alzheimer's disease mouse model using GluCEST MRI.
Alzheimers Dement. 2024 Sep 11. doi: 10.1002/alz.14190.
PubMed Abstract available

PICHET BINETTE A, Mammana A, Wisse L, Rossi M, et al
Associations between misfolded alpha-synuclein aggregates and Alzheimer's disease pathology in vivo.
Alzheimers Dement. 2024 Sep 11. doi: 10.1002/alz.14225.
PubMed Abstract available

BACHMANN D, Saake A, Studer S, Buchmann A, et al
Hypertension and cerebral blood flow in the development of Alzheimer's disease.
Alzheimers Dement. 2024 Sep 10. doi: 10.1002/alz.14233.
PubMed Abstract available

SALMAN Y, Gerard T, Huyghe L, Colmant L, et al
Amygdala atrophies in specific subnuclei in preclinical Alzheimer's disease.
Alzheimers Dement. 2024 Sep 10. doi: 10.1002/alz.14235.
PubMed Abstract available

Alzheimer's Association launches new journal on the impacts of behavioral, social, and economic factors on health and dementia care in aging.
Alzheimers Dement. 2024 Sep 6. doi: 10.1002/alz.14240.
PubMed

CARRILLO MC, Mahinrad S, Snyder HM, Khachaturian Z, et al
The role of the Alzheimer's Association in the genesis of Alzheimer's Disease Neuroimaging Initiative.
Alzheimers Dement. 2024 Sep 6. doi: 10.1002/alz.14228.
PubMed Abstract available

ARNOLD SE, Hyman BT, Betensky RA, Dodge HH, et al
Pathways to personalized medicine-Embracing heterogeneity for progress in clinical therapeutics research in Alzheimer's disease.
Alzheimers Dement. 2024 Sep 6. doi: 10.1002/alz.14063.
PubMed Abstract available

VANDERLIP CR, Lee MD, Stark CEL
Cognitive modeling of the Mnemonic Similarity Task as a digital biomarker for Alzheimer's disease.
Alzheimers Dement. 2024 Sep 6. doi: 10.1002/alz.14163.
PubMed Abstract available

VANDERLIP CR, Stark CEL
Digital cognitive assessments as low-burden markers for predicting future cognitive decline and tau accumulation across the Alzheimer's spectrum.
Alzheimers Dement. 2024 Sep 6. doi: 10.1002/alz.14154.
PubMed Abstract available

VERDI S, Rutherford S, Fraza C, Tosun D, et al
Personalizing progressive changes to brain structure in Alzheimer's disease using normative modeling.
Alzheimers Dement. 2024 Sep 5. doi: 10.1002/alz.14174.
PubMed Abstract available

LAO P, Young CB, Ezeh C, Lacayo B, et al
Loneliness, cerebrovascular and Alzheimer's disease pathology, and cognition.
Alzheimers Dement. 2024 Sep 5. doi: 10.1002/alz.14196.
PubMed Abstract available

SKIRROW C, Meepegama U, Weston J, Miller MJ, et al
Storyteller in ADNI4: Application of an early Alzheimer's disease screening tool using brief, remote, and speech-based testing.
Alzheimers Dement. 2024 Sep 5. doi: 10.1002/alz.14206.
PubMed Abstract available

GUNASEKARAN TI, Reyes-Dumeyer D, Faber KM, Goate A, et al
Missense and loss-of-function variants at GWAS loci in familial Alzheimer's disease.
Alzheimers Dement. 2024 Sep 5. doi: 10.1002/alz.14221.
PubMed Abstract available

GONZALEZ-GOMEZ R, Legaz A, Moguilner S, Cruzat J, et al
Educational disparities in brain health and dementia across Latin America and the United States.
Alzheimers Dement. 2024;20:5912-5925.
PubMed Abstract available

GODOY-LUGO JA, Thorwald MA, Cacciottolo M, D'Agostino C, et al
Air pollution amyloidogenesis is attenuated by the gamma-secretase modulator GSM-15606.
Alzheimers Dement. 2024;20:6107-6114.
PubMed Abstract available

CLARK LR, Erickson CM, Chin NA, Basche KE, et al
Psychosocial implications of learning amyloid PET results in an observational cohort.
Alzheimers Dement. 2024;20:6579-6589.
PubMed Abstract available

DUGGAN MR, Yang Z, Cui Y, Dark HE, et al
Proteomic analyses reveal plasma EFEMP1 and CXCL12 as biomarkers and determinants of neurodegeneration.
Alzheimers Dement. 2024;20:6486-6505.
PubMed Abstract available

ARANI A, Borowski B, Felmlee J, Reid RI, et al
Design and validation of the ADNI MR protocol.
Alzheimers Dement. 2024;20:6615-6621.
PubMed Abstract available

LI Y, Wang L, Zhong J, Xu H, et al
Impaired glymphatic function as a biomarker for subjective cognitive decline: An exploratory dual cohort study.
Alzheimers Dement. 2024;20:6542-6555.
PubMed Abstract available

VERBERK IMW, Jutte J, Kingma MY, Vigneswaran S, et al
Development of thresholds and a visualization tool for use of a blood test in routine clinical dementia practice.
Alzheimers Dement. 2024;20:6115-6132.
PubMed Abstract available

SCHAUER SP, Cho CH, Novikova G, Roth GA, et al
Primate cerebrospinal fluid CHI3L1 reflects brain TREM2 agonism.
Alzheimers Dement. 2024;20:5861-5888.
PubMed Abstract available

MORCILLO-NIETO AO, Zsadanyi SE, Arriola-Infante JE, Carmona-Iragui M, et al
Characterization of white matter hyperintensities in Down syndrome.
Alzheimers Dement. 2024;20:6527-6541.
PubMed Abstract available

MARSH TW, Western D, Timsina J, Gorijala P, et al
A genetic and proteomic comparison of key AD biomarkers across tissues.
Alzheimers Dement. 2024;20:6423-6440.
PubMed Abstract available

SHAO K, Hu X, Kleineidam L, Stark M, et al
Amyloid and SCD jointly predict cognitive decline across Chinese and German cohorts.
Alzheimers Dement. 2024;20:5926-5939.
PubMed Abstract available

JOHNSON AL, Chin NA, Piasecki TM, Conner KL, et al
COVID-19 outcomes among patients with dementia and age-matched controls who were hospitalized in 21 US health-care systems.
Alzheimers Dement. 2024;20:6395-6406.
PubMed Abstract available

ACOSTA-URIBE J, Villegas-Lanau A, Vallejo D, Ramirez-Aguilar L, et al
Primary lateral sclerosis associated with PSEN1 Pro284Leu variant in a Colombian family: Clinical and neuropathological features.
Alzheimers Dement. 2024;20:6384-6394.
PubMed Abstract available

CAPPA SF, Ribaldi F, Chicherio C, Frisoni GB, et al
Subjective cognitive decline: Memory complaints, cognitive awareness, and metacognition.
Alzheimers Dement. 2024;20:6622-6631.
PubMed Abstract available

A genome-wide association meta-analysis of all-cause and vascular dementia.
Alzheimers Dement. 2024;20:5973-5995.
PubMed Abstract available

WISCH JK, Gordon BA, Barthelemy NR, Horie K, et al
Predicting continuous amyloid PET values with CSF tau phosphorylation occupancies.
Alzheimers Dement. 2024;20:6365-6373.
PubMed Abstract available

MAGANA-RAMIREZ CM, Irizarry-Martinez G, Gillen DL, Grill JD, et al
Reasons for undergoing amyloid imaging among diverse enrollees in the A4 study.
Alzheimers Dement. 2024;20:6060-6069.
PubMed Abstract available

KLOSKE CM, Belloy ME, Blue EE, Bowman GR, et al
Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference.
Alzheimers Dement. 2024;20:6590-6605.
PubMed Abstract available

THANAPORNSANGSUTH P, Booncharoen K, Khieukhajee J, Luechaipanit W, et al
The Bayesian approach for real-world implementation of plasma p-tau217 in tertiary care memory clinics in Thailand.
Alzheimers Dement. 2024;20:6456-6467.
PubMed Abstract available

ROH HW, Chauhan N, Seo SW, Choi SH, et al
Assessing cognitive impairment and disability in older adults through the lens of whole brain white matter patterns.
Alzheimers Dement. 2024;20:6032-6044.
PubMed Abstract available

YU X, Shi R, Zhou X, Zhang M, et al
Correlations between plasma markers and brain Abeta deposition across the AD continuum: Evidence from SILCODE.
Alzheimers Dement. 2024;20:6170-6182.
PubMed Abstract available

LIU C, Liu R, Tian N, Fa W, et al
Cardiometabolic multimorbidity, peripheral biomarkers, and dementia in rural older adults: The MIND-China study.
Alzheimers Dement. 2024;20:6133-6145.
PubMed Abstract available

August 2024

REDDY JS, Heath L, Linden AV, Allen M, et al
Bridging the gap: Multi-omics profiling of brain tissue in Alzheimer's disease and older controls in multi-ethnic populations.
Alzheimers Dement. 2024 Aug 30. doi: 10.1002/alz.14208.
PubMed Abstract available

JIANG Y, Neal J, Sompol P, Yener G, et al
Parallel electrophysiological abnormalities due to COVID-19 infection and to Alzheimer's disease and related dementia.
Alzheimers Dement. 2024 Aug 29. doi: 10.1002/alz.14089.
PubMed Abstract available

SMITH RG, Pishva E, Kouhsar M, Imm J, et al
Blood DNA methylomic signatures associated with CSF biomarkers of Alzheimer's disease in the EMIF-AD study.
Alzheimers Dement. 2024 Aug 28. doi: 10.1002/alz.14098.
PubMed Abstract available

LEBRUN A, Leprince Y, Lagarde J, Olivieri P, et al
How fiber bundle alterations differ in presumed LATE and amnestic Alzheimer's disease.
Alzheimers Dement. 2024 Aug 28. doi: 10.1002/alz.14156.
PubMed Abstract available

WANG Z, Song B, Wang J, Wang X, et al
Alzheimer's disease and its family history reduce the risk of non-Hodgkin's lymphoma: A Mendelian randomization study.
Alzheimers Dement. 2024 Aug 27. doi: 10.1002/alz.14205.
PubMed

ROPRI AS, Lam TG, Kalia V, Buchanan HM, et al
Alzheimer's disease CSF biomarkers correlate with early pathology and alterations in neuronal and glial gene expression.
Alzheimers Dement. 2024 Aug 27. doi: 10.1002/alz.14194.
PubMed Abstract available

Correction to "Effect of gamification with a support partner to increase physical activity in older adults at risk for Alzheimer's disease: The STEP 4Life randomized clinical trial".
Alzheimers Dement. 2024 Aug 27. doi: 10.1002/alz.14183.
PubMed

HOU T, Liu K, Fa W, Liu C, et al
Association of polygenic risk scores with Alzheimer's disease and plasma biomarkers among Chinese older adults: A community-based study.
Alzheimers Dement. 2024 Aug 22. doi: 10.1002/alz.13924.
PubMed Abstract available

NORAMBUENA A, Sagar VK, Wang Z, Raut P, et al
Disrupted mitochondrial response to nutrients is a presymptomatic event in the cortex of the APP(SAA) knock-in mouse model of Alzheimer's disease.
Alzheimers Dement. 2024 Aug 22. doi: 10.1002/alz.14144.
PubMed Abstract available

LIZAMA BN, Williams C, North HA, Pandey K, et al
CT1812 biomarker signature from a meta-analysis of CSF proteomic findings from two Phase 2 clinical trials in Alzheimer's disease.
Alzheimers Dement. 2024 Aug 21. doi: 10.1002/alz.14152.
PubMed Abstract available

GEIGENMULLER JN, Tari AR, Wisloff U, Walker TL, et al
The relationship between adult hippocampal neurogenesis and cognitive impairment in Alzheimer's disease.
Alzheimers Dement. 2024 Aug 21. doi: 10.1002/alz.14179.
PubMed Abstract available

WALTER S, Long R, Hummel CH
"Make research more people-centered": Two ADNI participants share recommendations for more inclusive Alzheimer's disease research.
Alzheimers Dement. 2024 Aug 21. doi: 10.1002/alz.14070.
PubMed

Alzheimer's Association Dementia Care Provider Roundtable funds research aimed at improving care interactions in assisted living communities.
Alzheimers Dement. 2024 Aug 14. doi: 10.1002/alz.14198.
PubMed

LIU R, Durbin-Johnson B, Paciotti B, Liu AT, et al
Metabolic dysfunctions predict the development of Alzheimer's disease: Statistical and machine learning analysis of EMR data.
Alzheimers Dement. 2024 Aug 14. doi: 10.1002/alz.14101.
PubMed Abstract available

POVALA G, De Bastiani MA, Bellaver B, Ferreira PCL, et al
Omics-derived biological modules reflect metabolic brain changes in Alzheimer's disease.
Alzheimers Dement. 2024 Aug 14. doi: 10.1002/alz.14095.
PubMed Abstract available

MISIURA M, Munkombwe C, Igwe K, Verble DD, et al
Neuroimaging correlates of Alzheimer's disease biomarker concentrations in a racially diverse high-risk cohort of middle-aged adults.
Alzheimers Dement. 2024 Aug 13. doi: 10.1002/alz.14051.
PubMed Abstract available

AISEN PS, Donohue MC, Raman R, Rafii MS, et al
The Alzheimer's Disease Neuroimaging Initiative Clinical Core.
Alzheimers Dement. 2024 Aug 13. doi: 10.1002/alz.14167.
PubMed Abstract available

SUN P, He Z, Li A, Yang J, et al
Spatial and temporal patterns of cortical mean diffusivity in Alzheimer's disease and suspected non-Alzheimer's disease pathophysiology.
Alzheimers Dement. 2024 Aug 12. doi: 10.1002/alz.14176.
PubMed Abstract available

ZHANG YJ, Cheng Y, Tang HL, Yue Q, et al
APOE epsilon4-associated downregulation of the IL-7/IL-7R pathway in effector memory T cells: Implications for Alzheimer's disease.
Alzheimers Dement. 2024 Aug 11. doi: 10.1002/alz.14173.
PubMed Abstract available

ZHANG YR, Wu BS, Chen SD, Yang L, et al
Whole exome sequencing analyses identified novel genes for Alzheimer's disease and related dementia.
Alzheimers Dement. 2024 Aug 11. doi: 10.1002/alz.14181.
PubMed Abstract available

BEYDOUN MA, Beydoun HA, Hedges DW, Erickson LD, et al
Infection burden, periodontal pathogens, and their interactive association with incident all-cause and Alzheimer's disease dementia in a large national survey.
Alzheimers Dement. 2024 Aug 8. doi: 10.1002/alz.14141.
PubMed Abstract available

WALSH S, Merrick R, Milne R, Nurock S, et al
Considering challenges for the new Alzheimer's drugs: Clinical, population, and health system perspectives.
Alzheimers Dement. 2024 Aug 6. doi: 10.1002/alz.14108.
PubMed Abstract available

BLUM D, Cailliau E, Behal H, Vidal JS, et al
Association of caffeine consumption with cerebrospinal fluid biomarkers in mild cognitive impairment and Alzheimer's disease: A BALTAZAR cohort study.
Alzheimers Dement. 2024 Aug 4. doi: 10.1002/alz.14169.
PubMed Abstract available

DRISCOLL IF, Lose S, Ma Y, Bendlin BB, et al
KLOTHO KL-VS heterozygosity is associated with diminished age-related neuroinflammation, neurodegeneration, and synaptic dysfunction in older cognitively unimpaired adults.
Alzheimers Dement. 2024;20:5347-5356.
PubMed Abstract available

CLOUSTON SAP, Hanes DW, Smith DM, Richmond LL, et al
Inequalities in accelerated cognitive decline: Resolving observational window bias using nested non-linear regression.
Alzheimers Dement. 2024;20:5540-5550.
PubMed Abstract available

GONIOTAKI D, Tamagnini F, Biasetti L, Rumpf SL, et al
Tau-mediated synaptic dysfunction is coupled with HCN channelopathy.
Alzheimers Dement. 2024;20:5629-5646.
PubMed Abstract available

JOHNS E, Vossler HA, Young CB, Carlson ML, et al
Florbetaben amyloid PET acquisition time: Influence on Centiloids and interpretation.
Alzheimers Dement. 2024;20:5299-5310.
PubMed Abstract available

SHEKARI M, Vallez Garcia D, Collij LE, Altomare D, et al
Stress testing the Centiloid: Precision and variability of PET quantification of amyloid pathology.
Alzheimers Dement. 2024;20:5102-5113.
PubMed Abstract available

ANDRIUTA D, Ottoy J, Ruthirakuhan M, Feliciano G, et al
Perivascular spaces, plasma GFAP, and speeded executive function in neurodegenerative diseases.
Alzheimers Dement. 2024;20:5800-5808.
PubMed Abstract available

FALCON C, Montesinos P, Vaclavu L, Kassinopoulos M, et al
Time-encoded ASL reveals lower cerebral blood flow in the early AD continuum.
Alzheimers Dement. 2024;20:5183-5197.
PubMed Abstract available

VARMA C, Luo E, Bostrom G, Bathini P, et al
Plasma and CSF biomarkers of aging and cognitive decline in Caribbean vervets.
Alzheimers Dement. 2024;20:5460-5480.
PubMed Abstract available

KRASNY S, Yan C, Hartley SL, Handen BL, et al
Assessing amyloid PET positivity and cognitive function in Down syndrome to guide clinical trials targeting amyloid.
Alzheimers Dement. 2024;20:5570-5577.
PubMed Abstract available

YOSHIDA K, Hata Y, Ichimata S, Tanaka R, et al
Prevalence and clinicopathological features of primary age-related tauopathy (PART): A large forensic autopsy study.
Alzheimers Dement. 2024;20:5411-5420.
PubMed Abstract available

EMERSIC A, Ashton NJ, Vrillon A, Lantero-Rodriguez J, et al
Cerebrospinal fluid p-tau181, 217, and 231 in definite Creutzfeldt-Jakob disease with and without concomitant pathologies.
Alzheimers Dement. 2024;20:5324-5337.
PubMed Abstract available

DABIN LC, Kersey H, Kim B, Acri DJ, et al
Loss of Inpp5d has disease-relevant and sex-specific effects on glial transcriptomes.
Alzheimers Dement. 2024;20:5311-5323.
PubMed Abstract available

July 2024

TRAVAGLIA A, Hoffmann S
Data sharing as the foundation of discovery: ADNI and breakthroughs in Alzheimer's disease.
Alzheimers Dement. 2024 Jul 30. doi: 10.1002/alz.14129.
PubMed Abstract available

GALLO LH, Akanda N, Autar K, Patel A, et al
A functional aged human iPSC-cortical neuron model recapitulates Alzheimer's disease, senescence, and the response to therapeutics.
Alzheimers Dement. 2024 Jul 30. doi: 10.1002/alz.14044.
PubMed Abstract available

LORENZINI L, Collij LE, Tesi N, Vilor-Tejedor N, et al
Alzheimer's disease genetic pathways impact cerebrospinal fluid biomarkers and imaging endophenotypes in non-demented individuals.
Alzheimers Dement. 2024 Jul 29. doi: 10.1002/alz.14096.
PubMed Abstract available

RAKET LL, Cummings J, Moscoso A, Villain N, et al
Scenarios for the long-term efficacy of amyloid-targeting therapies in the context of the natural history of Alzheimer's disease.
Alzheimers Dement. 2024 Jul 29. doi: 10.1002/alz.14134.
PubMed Abstract available

HU J, Zhang M, Zhang Y, Zhuang H, et al
Neurometabolic topography and associations with cognition in Alzheimer's disease: A whole-brain high-resolution 3D MRSI study.
Alzheimers Dement. 2024 Jul 29. doi: 10.1002/alz.14137.
PubMed Abstract available

SUN Y, Wang P, Zhao K, Chen P, et al
Structure-function coupling reveals the brain hierarchical structure dysfunction in Alzheimer's disease: A multicenter study.
Alzheimers Dement. 2024 Jul 28. doi: 10.1002/alz.14123.
PubMed Abstract available

QUESNEL MJ, Labonte A, Picard C, Bowie DC, et al
Osteopontin: A novel marker of pre-symptomatic sporadic Alzheimer's disease.
Alzheimers Dement. 2024 Jul 28. doi: 10.1002/alz.14065.
PubMed Abstract available

RITCHIE M, Witbracht M, Russ E, Sajjadi SA, et al
The utility of recruitment incentives in early Alzheimer's disease trials.
Alzheimers Dement. 2024 Jul 27. doi: 10.1002/alz.14143.
PubMed Abstract available

FALGAS N, Pena-Gonzalez M, Val-Guardiola A, Perez-Millan A, et al
Locus coeruleus integrity and neuropsychiatric symptoms in a cohort of early- and late-onset Alzheimer's disease.
Alzheimers Dement. 2024 Jul 25. doi: 10.1002/alz.14131.
PubMed Abstract available

LEUZY A, Raket LL, Villemagne VL, Klein G, et al
Harmonizing tau positron emission tomography in Alzheimer's disease: The CenTauR scale and the joint propagation model.
Alzheimers Dement. 2024 Jul 23. doi: 10.1002/alz.13908.
PubMed Abstract available

NATH A, Holtzman DM, Miller BL, Grinberg LT, et al
Insufficient evidence for an association between iatrogenic Alzheimer's disease and cadaveric pituitary-derived growth hormone.
Alzheimers Dement. 2024 Jul 22. doi: 10.1002/alz.14127.
PubMed Abstract available

DEAN HB, Greer RA, Yang SZ, Elston DS, et al
Multimerization of TREM2 is impaired by Alzheimer's disease-associated variants.
Alzheimers Dement. 2024 Jul 20. doi: 10.1002/alz.14124.
PubMed Abstract available

WARMENHOVEN N, Sanchez-Benavides G, Gonzalez-Escalante A, Mila-Aloma M, et al
CSF glial biomarkers are associated with cognition in individuals at risk of Alzheimer's disease.
Alzheimers Dement. 2024 Jul 19. doi: 10.1002/alz.13862.
PubMed Abstract available

GE YJ, Chen SD, Wu BS, Zhang YR, et al
Genome-wide meta-analysis identifies ancestry-specific loci for Alzheimer's disease.
Alzheimers Dement. 2024 Jul 18. doi: 10.1002/alz.14121.
PubMed Abstract available

LANSDALL CJ, Teng E, Chague J, Palanganda R, et al
Care partner-informed meaningful change thresholds for the Clinical Dementia Rating-Sum of Boxes for trials of early Alzheimer's disease.
Alzheimers Dement. 2024 Jul 17. doi: 10.1002/alz.14050.
PubMed Abstract available

ZHANG C, Jia Q, Zhu L, Hou J, et al
Suppressing UBE2N ameliorates Alzheimer's disease pathology through the clearance of amyloid beta.
Alzheimers Dement. 2024 Jul 17. doi: 10.1002/alz.14122.
PubMed Abstract available

WIESMAN AI, Gallego-Rudolf J, Villeneuve S, Baillet S, et al
Neurochemical organization of cortical proteinopathy and neurophysiology along the Alzheimer's disease continuum.
Alzheimers Dement. 2024 Jul 12. doi: 10.1002/alz.14110.
PubMed Abstract available

The Anne and Henry Zarrow Foundation makes second $5 million grant to Alzheimer's Association for research.
Alzheimers Dement. 2024 Jul 11. doi: 10.1002/alz.14116.
PubMed

FARRELL ME, Thibault EG, Becker JA, Price JC, et al
Spatial extent as a sensitive amyloid-PET metric in preclinical Alzheimer's disease.
Alzheimers Dement. 2024 Jul 10. doi: 10.1002/alz.14036.
PubMed Abstract available

LI M, Guan M, Lin J, Zhu K, et al
Early blood immune molecular alterations in cynomolgus monkeys with a PSEN1 mutation causing familial Alzheimer's disease.
Alzheimers Dement. 2024 Jul 7. doi: 10.1002/alz.14046.
PubMed Abstract available

DELVENNE A, Gobom J, Schindler SE, Kate MT, et al
CSF proteomic profiles of neurodegeneration biomarkers in Alzheimer's disease.
Alzheimers Dement. 2024 Jul 6. doi: 10.1002/alz.14103.
PubMed Abstract available

DAMUKA N, Irmen RE, Krizan I, Miller M, et al
Exploring microtubule dynamics in Alzheimer's disease: Longitudinal assessment using [(11)C]MPC-6827 PET imaging in rodent models of Alzheimer's-related pathology.
Alzheimers Dement. 2024 Jul 5. doi: 10.1002/alz.14083.
PubMed Abstract available

ARENAZA-URQUIJO EM, Boyle R, Casaletto K, Anstey KJ, et al
Sex and gender differences in cognitive resilience to aging and Alzheimer's disease.
Alzheimers Dement. 2024 Jul 5. doi: 10.1002/alz.13844.
PubMed Abstract available

DU L, Langhough RE, Wilson RE, Reyes RER, et al
Longitudinal plasma phosphorylated-tau217 and other related biomarkers in a non-demented Alzheimer's risk-enhanced sample.
Alzheimers Dement. 2024 Jul 5. doi: 10.1002/alz.14100.
PubMed Abstract available

KIM H, Lee S, Levine A, Huber B, et al
Novel measures of cognition and function for the AD spectrum in the Novel Measures for Alzheimer's Disease Prevention Trials (NoMAD) project: Psychometric properties, convergent validation, and contrasts with established measures.
Alzheimers Dement. 2024 Jul 4. doi: 10.1002/alz.13757.
PubMed Abstract available

GREYSEN SR, Oon AL, Harkins K, Rareshide C, et al
Effect of gamification with a support partner to increase physical activity in older adults at risk for Alzheimer's disease: The STEP 4Life randomized clinical trial.
Alzheimers Dement. 2024 Jul 4. doi: 10.1002/alz.14058.
PubMed Abstract available

DAYARATHNA T, Roseborough AD, Gomes J, Khazaee R, et al
Nanoscale flow cytometry-based quantification of blood-based extracellular vesicle biomarkers distinguishes MCI and Alzheimer's disease.
Alzheimers Dement. 2024 Jul 3. doi: 10.1002/alz.14087.
PubMed Abstract available

MORRIS JC, Buckles VD
The role of the Alzheimer's Disease Neuroimaging Initiative in establishing the Dominantly Inherited Alzheimer Network.
Alzheimers Dement. 2024 Jul 3. doi: 10.1002/alz.14106.
PubMed Abstract available

POLSINELLI AJ, Johnson S, Crouch A, Lane KA, et al
Neuropsychiatric symptom burden in early-onset and late-onset Alzheimer's disease as a function of age.
Alzheimers Dement. 2024 Jul 3. doi: 10.1002/alz.14042.
PubMed Abstract available

RAY NR, Kunkle BW, Hamilton-Nelson K, Kurup JT, et al
Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry.
Alzheimers Dement. 2024 Jul 3. doi: 10.1002/alz.13880.
PubMed Abstract available

UEKAWA K, Anfray A, Ahn SJ, Casey N, et al
tPA supplementation preserves neurovascular and cognitive function in Tg2576 mice.
Alzheimers Dement. 2024;20:4572-4582.
PubMed Abstract available

SINGH NA, Alnobani A, Graff-Radford J, Machulda MM, et al
Relationships between PET and blood plasma biomarkers in corticobasal syndrome.
Alzheimers Dement. 2024;20:4765-4774.
PubMed Abstract available

HEYWOOD A, Stocks J, Schneider JA, Arfanakis K, et al
In vivo effect of LATE-NC on integrity of white matter connections to the hippocampus.
Alzheimers Dement. 2024;20:4401-4410.
PubMed Abstract available

LLAMAS RODRIGUEZ J, van der Kouwe AJW, Oltmer J, Rosenblum E, et al
Entorhinal vessel density correlates with phosphorylated tau and TDP-43 pathology.
Alzheimers Dement. 2024;20:4649-4662.
PubMed Abstract available

GONZALEZ-BAUTISTA E, Mommeja M, de Mauleon A, Ismail Z, et al
Mild behavioral impairment domains are longitudinally associated with pTAU and metabolic biomarkers in dementia-free older adults.
Alzheimers Dement. 2024;20:4692-4701.
PubMed Abstract available

HUPER L, Steinacker P, Polyakova M, Mueller K, et al
Neurofilaments and progranulin are related to atrophy in frontotemporal lobar degeneration - A transdiagnostic study cross-validating atrophy and fluid biomarkers.
Alzheimers Dement. 2024;20:4461-4475.
PubMed Abstract available

ONOS KD, Lin PB, Pandey RS, Persohn SA, et al
Assessment of neurovascular uncoupling: APOE status is a key driver of early metabolic and vascular dysfunction.
Alzheimers Dement. 2024;20:4951-4969.
PubMed Abstract available

DUNHAM SJB, Avelar-Barragan J, Rothman JA, Adams ED, et al
Sex-specific associations between AD genotype and the microbiome of human amyloid beta knock-in (hAbeta-KI) mice.
Alzheimers Dement. 2024;20:4935-4950.
PubMed Abstract available

BUTLER CA, Mendoza Arvilla A, Milinkeviciute G, Da Cunha C, et al
The Abca7(V1613M) variant reduces Abeta generation, plaque load, and neuronal damage.
Alzheimers Dement. 2024;20:4914-4934.
PubMed Abstract available

June 2024

DEVANARAYAN V, Doherty T, Charil A, Sachdev P, et al
Plasma pTau217 predicts continuous brain amyloid levels in preclinical and early Alzheimer's disease.
Alzheimers Dement. 2024 Jun 28. doi: 10.1002/alz.14073.
PubMed Abstract available

LIANG Y, Liu C, Cheng M, Geng L, et al
The link between gut microbiome and Alzheimer's disease: From the perspective of new revised criteria for diagnosis and staging of Alzheimer's disease.
Alzheimers Dement. 2024 Jun 28. doi: 10.1002/alz.14057.
PubMed Abstract available

VOGELGSANG J, Hansen N, Stark M, Wagner M, et al
Plasma amyloid beta X-42/X-40 ratio and cognitive decline in suspected early and preclinical Alzheimer's disease.
Alzheimers Dement. 2024 Jun 28. doi: 10.1002/alz.13909.
PubMed Abstract available

DU Y, Guo T, Hao Y, Li C, et al
PKCdelta serves as a potential biomarker and therapeutic target for microglia-mediated neuroinflammation in Alzheimer's disease.
Alzheimers Dement. 2024 Jun 28. doi: 10.1002/alz.14047.
PubMed Abstract available

GUPTA L, Ma Y, Kohli A, Yang KL, et al
Alzheimer's disease biomarker burden in primary motor cortices is associated with poorer dexterity performance.
Alzheimers Dement. 2024 Jun 27. doi: 10.1002/alz.13899.
PubMed Abstract available

JACK CR JR, Andrews JS, Beach TG, Buracchio T, et al
Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup.
Alzheimers Dement. 2024 Jun 27. doi: 10.1002/alz.13859.
PubMed Abstract available

RIBEIRO FC, Cozachenco D, Argyrousi EK, Staniszewski A, et al
The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer's disease.
Alzheimers Dement. 2024 Jun 27. doi: 10.1002/alz.14034.
PubMed Abstract available

WILCOCK DM, Lamb BT
The importance of continuing development of novel animal models of Alzheimer's disease and Alzheimer's disease and related dementias.
Alzheimers Dement. 2024 Jun 26. doi: 10.1002/alz.14105.
PubMed

AMINI S, Hao B, Yang J, Karjadi C, et al
Prediction of Alzheimer's disease progression within 6 years using speech: A novel approach leveraging language models.
Alzheimers Dement. 2024 Jun 25. doi: 10.1002/alz.13886.
PubMed Abstract available

Correction to "CALHM2 V136G polymorphism reduces astrocytic ATP release and is associated with depressive symptoms and Alzheimer's disease risk".
Alzheimers Dement. 2024 Jun 23. doi: 10.1002/alz.13822.
PubMed

BAIARDI S, Hansson O, Levin J, Parchi P, et al
In vivo detection of Alzheimer's and Lewy body disease concurrence: Clinical implications and future perspectives.
Alzheimers Dement. 2024 Jun 21. doi: 10.1002/alz.14039.
PubMed Abstract available

WANG G, Cutter G, Oxtoby NP, Shan G, et al
Statistical considerations when estimating time-saving treatment effects in Alzheimer's disease clinical trials.
Alzheimers Dement. 2024 Jun 21. doi: 10.1002/alz.14035.
PubMed Abstract available

BECKMAN D, Diniz GB, Ott S, Hobson B, et al
Temporal progression of tau pathology and neuroinflammation in a rhesus monkey model of Alzheimer's disease.
Alzheimers Dement. 2024 Jun 21. doi: 10.1002/alz.13868.
PubMed Abstract available

MORALES J, Gabriel N, Natarajan L, LaCroix AZ, et al
Pharmacoepidemiology evaluation of bumetanide as a potential candidate for drug repurposing for Alzheimer's disease.
Alzheimers Dement. 2024 Jun 21. doi: 10.1002/alz.13872.
PubMed Abstract available

LI Q, Su S, Feng Y, Jia M, et al
Potential role of blood pressure variability and plasma neurofilament light in the mechanism of comorbidity between Alzheimer's disease and cerebral small vessel disease.
Alzheimers Dement. 2024 Jun 19. doi: 10.1002/alz.14056.
PubMed Abstract available

HAMLIN D, Ryall C, Turner C, Faull RLM, et al
Characterization of neurofibrillary tangle immunophenotype signatures to classify tangle maturity in Alzheimer's disease.
Alzheimers Dement. 2024 Jun 17. doi: 10.1002/alz.13922.
PubMed Abstract available

YAO Y, Muench M, Alle T, Zhang B, et al
A small-molecule microtubule-stabilizing agent safely reduces Abeta plaque and tau pathology in transgenic mouse models of Alzheimer's disease.
Alzheimers Dement. 2024 Jun 17. doi: 10.1002/alz.13875.
PubMed Abstract available

BERRON D, Olsson E, Andersson F, Janelidze S, et al
Remote and unsupervised digital memory assessments can reliably detect cognitive impairment in Alzheimer's disease.
Alzheimers Dement. 2024 Jun 12. doi: 10.1002/alz.13919.
PubMed Abstract available

DING X, Yin L, Zhang L, Zhang Y, et al
Diabetes accelerates Alzheimer's disease progression in the first year post mild cognitive impairment diagnosis.
Alzheimers Dement. 2024 Jun 12. doi: 10.1002/alz.13882.
PubMed Abstract available

LIU Y, Xiao X, Yang Y, Yao R, et al
The risk of Alzheimer's disease and cognitive impairment characteristics in eight mental disorders: A UK Biobank observational study and Mendelian randomization analysis.
Alzheimers Dement. 2024 Jun 11. doi: 10.1002/alz.14049.
PubMed Abstract available

LEE JK, Raghavan S, Christenson LR, Frank RD, et al
Longitudinal associations of reproductive factors and exogeneous estrogens with neuroimaging biomarkers of Alzheimer's disease and cerebrovascular disease.
Alzheimers Dement. 2024 Jun 11. doi: 10.1002/alz.13890.
PubMed Abstract available

YEW PY, Devera R, Liang Y, Khalifa RAE, et al
Unraveling the multiple chronic conditions patterns among people with Alzheimer's disease and related dementia: A machine learning approach to incorporate synergistic interactions.
Alzheimers Dement. 2024 Jun 11. doi: 10.1002/alz.13923.
PubMed Abstract available

OVEISGHARAN S, Yu L, de Paiva Lopes K, Tasaki S, et al
Proteins linking APOE varepsilon4 with Alzheimer's disease.
Alzheimers Dement. 2024 Jun 10. doi: 10.1002/alz.13867.
PubMed Abstract available

YERRAMALLA MS, Darin-Mattsson A, Udeh-Momoh CT, Holleman J, et al
Cognitive reserve, cortisol, and Alzheimer's disease biomarkers: A memory clinic study.
Alzheimers Dement. 2024 Jun 4. doi: 10.1002/alz.13866.
PubMed Abstract available

SIRKIS DW, Warly Solsberg C, Johnson TP, Bonham LW, et al
Expansion of highly interferon-responsive T cells in early-onset Alzheimer's disease.
Alzheimers Dement. 2024 Jun 3. doi: 10.1002/alz.13892.
PubMed Abstract available

GUPTARAK J, Scaduto P, Tumurbaatar B, Zhang WR, et al
Cognitive integrity in Non-Demented Individuals with Alzheimer's Neuropathology is associated with preservation and remodeling of dendritic spines.
Alzheimers Dement. 2024 Jun 3. doi: 10.1002/alz.13900.
PubMed Abstract available

LIU ZT, Liu MH, Xiong Y, Wang YJ, et al
Crosstalk between bone and brain in Alzheimer's disease: Mechanisms, applications, and perspectives.
Alzheimers Dement. 2024 Jun 2. doi: 10.1002/alz.13864.
PubMed Abstract available

ARBER C, Belder CRS, Tomczuk F, Gabriele R, et al
The presenilin 1 mutation P436S causes familial Alzheimer's disease with elevated Abeta43 and atypical clinical manifestations.
Alzheimers Dement. 2024 Jun 2. doi: 10.1002/alz.13904.
PubMed Abstract available

COOPER JG, Ghodsi M, Stukas S, Leach S, et al
APOE epsilon4 carrier status modifies plasma p-tau181 concentrations in cognitively healthy super-seniors.
Alzheimers Dement. 2024;20:4373-4380.
PubMed Abstract available

ZHU Y, Park S, Kolady R, Zha W, et al
A systematic review/meta-analysis of prevalence and incidence rates illustrates systemic underrepresentation of individuals racialized as Asian and/or Asian-American in ADRD research.
Alzheimers Dement. 2024;20:4315-4330.
PubMed Abstract available

SCHNEIDER C, Prokopiou PC, Papp KV, Engels-Dominguez N, et al
Atrophy links lower novelty-related locus coeruleus connectivity to cognitive decline in preclinical AD.
Alzheimers Dement. 2024;20:3958-3971.
PubMed Abstract available

ARANHA MR, Montal V, van den Brink H, Pegueroles J, et al
Cortical microinfarcts in adults with Down syndrome assessed with 3T-MRI.
Alzheimers Dement. 2024;20:3906-3917.
PubMed Abstract available

WANG J, Huang Q, He K, Li J, et al
Presynaptic density determined by SV2A PET is closely associated with postsynaptic metabotropic glutamate receptor 5 availability and independent of amyloid pathology in early cognitive impairment.
Alzheimers Dement. 2024;20:3876-3888.
PubMed Abstract available

SILBERT LC, Roese NE, Krajbich V, Hurworth J, et al
White matter hyperintensities and the surrounding normal appearing white matter are associated with water channel disruption in the oldest old.
Alzheimers Dement. 2024;20:3839-3851.
PubMed Abstract available

May 2024

PANYARD DJ, Reus LM, Ali M, Liu J, et al
Post-GWAS multiomic functional investigation of the TNIP1 locus in Alzheimer's disease highlights a potential role for GPX3.
Alzheimers Dement. 2024 May 29. doi: 10.1002/alz.13848.
PubMed Abstract available

BISKADUROS A, Glodzik L, Saint Louis LA, Rusinek H, et al
Longitudinal trajectories of Alzheimer's disease CSF biomarkers and blood pressure in cognitively healthy subjects.
Alzheimers Dement. 2024 May 29. doi: 10.1002/alz.13800.
PubMed Abstract available

SOSA AL, Brucki SM, Crivelli L, Lopera FJ, et al
Advancements in dementia research, diagnostics, and care in Latin America: Highlights from the 2023 Alzheimer's Association International conference satellite symposium in Mexico City.
Alzheimers Dement. 2024 May 27. doi: 10.1002/alz.13850.
PubMed Abstract available

GARCIA RATES S, Garcia-Ayllon MS, Falgas N, Brangman SA, et al
Evidence for a novel neuronal mechanism driving Alzheimer's disease, upstream of amyloid.
Alzheimers Dement. 2024 May 23. doi: 10.1002/alz.13869.
PubMed Abstract available

LATIF-HERNANDEZ A, Yang T, Raymond-Butler R 3rd, Losada PM, et al
A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity-dependent synaptic and microglial transcriptomic changes in a late-stage Alzheimer's mouse model.
Alzheimers Dement. 2024 May 23. doi: 10.1002/alz.13857.
PubMed Abstract available

TOSUN D, Hausle Z, Iwaki H, Thropp P, et al
A cross-sectional study of alpha-synuclein seed amplification assay in Alzheimer's disease neuroimaging initiative: Prevalence and associations with Alzheimer's disease biomarkers and cognitive function.
Alzheimers Dement. 2024 May 21. doi: 10.1002/alz.13858.
PubMed Abstract available

MOGUILNER SG, Berezuk C, Bender AC, Pellerin KR, et al
Sleep functional connectivity, hyperexcitability, and cognition in Alzheimer's disease.
Alzheimers Dement. 2024 May 19. doi: 10.1002/alz.13861.
PubMed Abstract available

ZHANG Y, Ferreira PCL, Jacobsen E, Bellaver B, et al
Association of plasma biomarkers of Alzheimer's disease and related disorders with cognition and cognitive decline: The MYHAT population-based study.
Alzheimers Dement. 2024 May 16. doi: 10.1002/alz.13829.
PubMed Abstract available

HOU Y, Chu X, Park JH, Zhu Q, et al
Urolithin A improves Alzheimer's disease cognition and restores mitophagy and lysosomal functions.
Alzheimers Dement. 2024 May 16. doi: 10.1002/alz.13847.
PubMed Abstract available

BROWN C, Das S, Xie L, Nasrallah I, et al
Medial temporal lobe gray matter microstructure in preclinical Alzheimer's disease.
Alzheimers Dement. 2024 May 15. doi: 10.1002/alz.13832.
PubMed Abstract available

RUDOLPH MD, Sutphen CL, Register TC, Whitlow CT, et al
Associations among plasma, MRI, and amyloid PET biomarkers of Alzheimer's disease and related dementias and the impact of health-related comorbidities in a community-dwelling cohort.
Alzheimers Dement. 2024 May 15. doi: 10.1002/alz.13835.
PubMed Abstract available

KWAPONG WR, Tang F, Liu P, Zhang Z, et al
Choriocapillaris reduction accurately discriminates against early-onset Alzheimer's disease.
Alzheimers Dement. 2024 May 15. doi: 10.1002/alz.13871.
PubMed Abstract available

SUCHY-DICEY AM, Domoto-Reilly K, Nelson L, Jayadev S, et al
Epidemiology and prevalence of dementia and Alzheimer's disease in American Indians: Data from the Strong Heart Study.
Alzheimers Dement. 2024 May 15. doi: 10.1002/alz.13849.
PubMed Abstract available

KOTREDES KP, Pandey RS, Persohn S, Elderidge K, et al
Characterizing molecular and synaptic signatures in mouse models of late-onset Alzheimer's disease independent of amyloid and tau pathology.
Alzheimers Dement. 2024 May 12. doi: 10.1002/alz.13828.
PubMed Abstract available

VALLETTA M, Vetrano DL, Rizzuto D, Winblad B, et al
Blood biomarkers of Alzheimer's disease in the community: Variation by chronic diseases and inflammatory status.
Alzheimers Dement. 2024 May 8. doi: 10.1002/alz.13860.
PubMed Abstract available

WOJTAS AM, Dammer EB, Guo Q, Ping L, et al
Proteomic changes in the human cerebrovasculature in Alzheimer's disease and related tauopathies linked to peripheral biomarkers in plasma and cerebrospinal fluid.
Alzheimers Dement. 2024 May 7. doi: 10.1002/alz.13821.
PubMed Abstract available

FU J, Lai X, Zhang C, Wei Q, et al
Correlation analysis of peripheral platelet markers and disease phenotypes in Alzheimer's disease.
Alzheimers Dement. 2024 May 7. doi: 10.1002/alz.13841.
PubMed Abstract available

GALVIN JE, Cummings JL, Benea ML, de Moor C, et al
Generating real-world evidence in Alzheimer's disease: Considerations for establishing a core dataset.
Alzheimers Dement. 2024 May 6. doi: 10.1002/alz.13785.
PubMed Abstract available

AHMED C, Greve HJ, Garza-Lombo C, Malley JA, et al
Peripheral HMGB1 is linked to O(3) pathology of disease-associated astrocytes and amyloid.
Alzheimers Dement. 2024;20:3551-3566.
PubMed Abstract available

PETKUS AJ, Wang X, Younan D, Salminen LE, et al
20-year depressive symptoms, dementia, and structural neuropathology in older women.
Alzheimers Dement. 2024;20:3472-3484.
PubMed Abstract available

XHIMA K, Ottoy J, Gibson E, Zukotynski K, et al
Distinct spatial contributions of amyloid pathology and cerebral small vessel disease to hippocampal morphology.
Alzheimers Dement. 2024;20:3687-3695.
PubMed Abstract available

BOLLACK A, Collij LE, Garcia DV, Shekari M, et al
Investigating reliable amyloid accumulation in Centiloids: Results from the AMYPAD Prognostic and Natural History Study.
Alzheimers Dement. 2024;20:3429-3441.
PubMed Abstract available

CHO S, Olm CA, Ash S, Shellikeri S, et al
Automatic classification of AD pathology in FTD phenotypes using natural speech.
Alzheimers Dement. 2024;20:3416-3428.
PubMed Abstract available

CHEN T, O'Gorman J, Castrillo-Viguera C, Rajagovindan R, et al
Results from the long-term extension of PRIME: A randomized Phase 1b trial of aducanumab.
Alzheimers Dement. 2024;20:3406-3415.
PubMed Abstract available

QIU T, Liu ZQ, Rheault F, Legarreta JH, et al
Structural white matter properties and cognitive resilience to tau pathology.
Alzheimers Dement. 2024;20:3364-3377.
PubMed Abstract available

JONAITIS EM, Hermann BP, Mueller KD, Clark LR, et al
Longitudinal normative standards for cognitive tests and composites using harmonized data from two Wisconsin AD-risk-enriched cohorts.
Alzheimers Dement. 2024;20:3305-3321.
PubMed Abstract available

CORONEL-OLIVEROS C, Gomez RG, Ranasinghe K, Sainz-Ballesteros A, et al
Viscous dynamics associated with hypoexcitation and structural disintegration in neurodegeneration via generative whole-brain modeling.
Alzheimers Dement. 2024;20:3228-3250.
PubMed Abstract available

MELCHER EM, Vilen L, Pfaff A, Lim S, et al
Deriving life-course residential histories in brain bank cohorts: A feasibility study.
Alzheimers Dement. 2024;20:3219-3227.
PubMed Abstract available

KAPASI A, Yu L, Leurgans SE, Agrawal S, et al
Association between hippocampal microglia, AD and LATE-NC, and cognitive decline in older adults.
Alzheimers Dement. 2024;20:3193-3202.
PubMed Abstract available

MEYER MR, Kirmess KM, Eastwood S, Wente-Roth TL, et al
Clinical validation of the PrecivityAD2 blood test: A mass spectrometry-based test with algorithm combining %p-tau217 and Abeta42/40 ratio to identify presence of brain amyloid.
Alzheimers Dement. 2024;20:3179-3192.
PubMed Abstract available

HILLERSTROM H, Fisher R, Janicki MP, Chicoine B, et al
Adapting prescribing criteria for amyloid-targeted antibodies for adults with Down syndrome.
Alzheimers Dement. 2024;20:3649-3656.
PubMed Abstract available

HE K, Li B, Wang J, Wang Y, et al
APOE epsilon4 is associated with decreased synaptic density in cognitively impaired participants.
Alzheimers Dement. 2024;20:3157-3166.
PubMed Abstract available

April 2024

2024 Alzheimer's disease facts and figures.
Alzheimers Dement. 2024 Apr 30. doi: 10.1002/alz.13809.
PubMed Abstract available

SASNER M, Preuss C, Pandey RS, Uyar A, et al
In vivo validation of late-onset Alzheimer's disease genetic risk factors.
Alzheimers Dement. 2024 Apr 30. doi: 10.1002/alz.13840.
PubMed Abstract available

EARNEST T, Bani A, Ha SM, Hobbs DA, et al
Data-driven decomposition and staging of flortaucipir uptake in Alzheimer's disease.
Alzheimers Dement. 2024 Apr 29. doi: 10.1002/alz.13769.
PubMed Abstract available

PANDEY RS, Arnold M, Batra R, Krumsiek J, et al
Metabolomics profiling reveals distinct, sex-specific signatures in serum and brain metabolomes in mouse models of Alzheimer's disease.
Alzheimers Dement. 2024 Apr 27. doi: 10.1002/alz.13851.
PubMed Abstract available

HU HY, Hu H, Jiang J, Bi YL, et al
Echocardiographic measures of the left heart and cerebrospinal fluid biomarkers of Alzheimer's disease pathology in cognitively intact adults: The CABLE study.
Alzheimers Dement. 2024 Apr 27. doi: 10.1002/alz.13837.
PubMed Abstract available

LEVIN J, Baiardi S, Quadalti C, Rossi M, et al
alpha-Synuclein seed amplification assay detects Lewy body co-pathology in autosomal dominant Alzheimer's disease late in the disease course and dependent on Lewy pathology burden.
Alzheimers Dement. 2024 Apr 26. doi: 10.1002/alz.13818.
PubMed Abstract available

ZHANG J, Chen H, Wang J, Huang Q, et al
Linking white matter hyperintensities to regional cortical thinning, amyloid deposition, and synaptic density loss in Alzheimer's disease.
Alzheimers Dement. 2024 Apr 22. doi: 10.1002/alz.13845.
PubMed Abstract available

SAADMAAN G, Dalmasso MC, Ramirez A, Hiltunen M, et al
Alzheimer's disease genetic risk score and neuroimaging in the FINGER lifestyle trial.
Alzheimers Dement. 2024 Apr 22. doi: 10.1002/alz.13843.
PubMed Abstract available

TESI N, van der Lee S, Hulsman M, van Schoor NM, et al
Cognitively healthy centenarians are genetically protected against Alzheimer's disease.
Alzheimers Dement. 2024 Apr 18. doi: 10.1002/alz.13810.
PubMed Abstract available

MOLINA-HENRY DP, Raman R, Liu A, Langford O, et al
Racial and ethnic differences in plasma biomarker eligibility for a preclinical Alzheimer's disease trial.
Alzheimers Dement. 2024 Apr 17. doi: 10.1002/alz.13803.
PubMed Abstract available

LOPEZ DC, White ZJ, Hall SE
Anxiety in Alzheimer's disease rats is independent of memory and impacted by genotype, age, sex, and exercise.
Alzheimers Dement. 2024 Apr 16. doi: 10.1002/alz.13813.
PubMed Abstract available

HOMANICS GE, Park JE, Bailey L, Schaeffer DJ, et al
Early molecular events of autosomal-dominant Alzheimer's disease in marmosets with PSEN1 mutations.
Alzheimers Dement. 2024 Apr 4. doi: 10.1002/alz.13806.
PubMed Abstract available

LEE S, Hecker J, Hahn G, Mullin K, et al
On the effect heterogeneity of established disease susceptibility loci for Alzheimer's disease across different genetic ancestries.
Alzheimers Dement. 2024 Apr 2. doi: 10.1002/alz.13796.
PubMed Abstract available

MUIR RT, Hill MD, Black SE, Smith EE, et al
Minimal clinically important difference in Alzheimer's disease: Rapid review.
Alzheimers Dement. 2024 Apr 1. doi: 10.1002/alz.13770.
PubMed Abstract available

Critical Alzheimer's disease legislation advances in Congress.
Alzheimers Dement. 2024;20:3141-3142.
PubMed

ISLAM T, Kvartsberg H, Sehrawat A, Kac PR, et al
Novel ultrasensitive immunoassay for the selective quantification of tau oligomers and related soluble aggregates.
Alzheimers Dement. 2024;20:2894-2905.
PubMed Abstract available

KATSUMATA Y, Fardo DW, Shade LMP, Wu X, et al
Genetic associations with dementia-related proteinopathy: Application of item response theory.
Alzheimers Dement. 2024;20:2906-2921.
PubMed Abstract available

DATTA D, Perone I, Wijegunawardana D, Liang F, et al
Nanoscale imaging of pT217-tau in aged rhesus macaque entorhinal and dorsolateral prefrontal cortex: Evidence of interneuronal trafficking and early-stage neurodegeneration.
Alzheimers Dement. 2024;20:2843-2860.
PubMed Abstract available

DESIMONE JC, Wang WE, Loewenstein DA, Duara R, et al
Diffusion MRI relates to plasma Abeta42/40 in PET negative participants without dementia.
Alzheimers Dement. 2024;20:2830-2842.
PubMed Abstract available

ARMSTRONG MJ, LaBarre B, Sovich K, Maixner SM, et al
Patient- and proxy-reported quality of life in advanced dementia with Lewy bodies.
Alzheimers Dement. 2024;20:2719-2730.
PubMed Abstract available

JOSEPH-MATHURIN N, Feldman RL, Lu R, Shirzadi Z, et al
Presenilin-1 mutation position influences amyloidosis, small vessel disease, and dementia with disease stage.
Alzheimers Dement. 2024;20:2680-2697.
PubMed Abstract available

YOUNG CB, Smith V, Karjadi C, Grogan SM, et al
Speech patterns during memory recall relates to early tau burden across adulthood.
Alzheimers Dement. 2024;20:2552-2563.
PubMed Abstract available

FONSECA CS, Baker SL, Dobyns L, Janabi M, et al
Tau accumulation and atrophy predict amyloid independent cognitive decline in aging.
Alzheimers Dement. 2024;20:2526-2537.
PubMed Abstract available

CHEN KL, Wang MY, Wu J, Zuo CT, et al
Incremental value of amyloid PET in a tertiary memory clinic setting in China.
Alzheimers Dement. 2024;20:2516-2525.
PubMed Abstract available

RITCHIE M, Salazar CR, Gillen DL, Grill JD, et al
Post-disclosure distress among racial and ethnic groups in a preclinical AD trial.
Alzheimers Dement. 2024;20:2508-2515.
PubMed Abstract available

KLEIN EG, Schroeder K, Wessels AM, Phipps A, et al
How donanemab data address the coverage with evidence development questions.
Alzheimers Dement. 2024;20:3127-3140.
PubMed Abstract available

EDISON P
Astroglial activation: Current concepts and future directions.
Alzheimers Dement. 2024;20:3034-3053.
PubMed Abstract available

ALBRECHT JS, Scherf A, Ryan KA, Falvey JR, et al
Impact of dementia and socioeconomic disadvantage on days at home after traumatic brain injury among older Medicare beneficiaries: A cohort study.
Alzheimers Dement. 2024;20:2364-2372.
PubMed Abstract available

HINTON L, Tran D, Peak K, Meyer OL, et al
Mapping racial and ethnic healthcare disparities for persons living with dementia: A scoping review.
Alzheimers Dement. 2024;20:3000-3020.
PubMed Abstract available

March 2024

DUCHATEAU L, Wawrzyniak N, Sleegers K
The ABC's of Alzheimer risk gene ABCA7.
Alzheimers Dement. 2024 Mar 31. doi: 10.1002/alz.13805.
PubMed Abstract available

BUCHHOLZ S, Zempel H
The six brain-specific TAU isoforms and their role in Alzheimer's disease and related neurodegenerative dementia syndromes.
Alzheimers Dement. 2024 Mar 31. doi: 10.1002/alz.13784.
PubMed Abstract available

DAKTERZADA F, Jove M, Cantero JL, Mota-Martorell N, et al
The shift in the fatty acid composition of the circulating lipidome in Alzheimer's disease.
Alzheimers Dement. 2024 Mar 27. doi: 10.1002/alz.13792.
PubMed Abstract available

RAHIMZADEH N, Srinivasan SS, Zhang J, Swarup V, et al
Gene networks and systems biology in Alzheimer's disease: Insights from multi-omics approaches.
Alzheimers Dement. 2024 Mar 27. doi: 10.1002/alz.13790.
PubMed Abstract available

VAN VELUW SJ, Young MJ
Ethical considerations for the use of anti-amyloid immunotherapy in patients with early Alzheimer's disease.
Alzheimers Dement. 2024 Mar 25. doi: 10.1002/alz.13795.
PubMed

SINTINI I, Singh NA, Li D, Mielke MM, et al
Plasma glial fibrillary acidic protein in the visual and language variants of Alzheimer's disease.
Alzheimers Dement. 2024 Mar 25. doi: 10.1002/alz.13713.
PubMed Abstract available

WANG Y, Sarnowski C, Lin H, Pitsillides AN, et al
Key variants via the Alzheimer's Disease Sequencing Project whole genome sequence data.
Alzheimers Dement. 2024 Mar 21. doi: 10.1002/alz.13705.
PubMed Abstract available

LARSEN FK, Baksh RA, McGlinchey E, Langballe EM, et al
Age of Alzheimer's disease diagnosis in people with Down syndrome and associated factors: Results from the Horizon 21 European Down syndrome consortium.
Alzheimers Dement. 2024 Mar 20. doi: 10.1002/alz.13779.
PubMed Abstract available

AMIRI S, Keffeler JI, Crain DR, Denney JT, et al
Racial, ethnic, and rural disparities in distance to physicians among decedents with Alzheimer's disease and related dementias in Washington State.
Alzheimers Dement. 2024 Mar 20. doi: 10.1002/alz.13756.
PubMed Abstract available

HUANG SY, Zhang YR, Guo Y, Du J, et al
Glymphatic system dysfunction predicts amyloid deposition, neurodegeneration, and clinical progression in Alzheimer's disease.
Alzheimers Dement. 2024 Mar 19. doi: 10.1002/alz.13789.
PubMed Abstract available

HOWARD R, Cort E, Rawlinson C, Wiegand M, et al
Adapted problem adaptation therapy for depression in mild to moderate Alzheimer's disease dementia: A randomized controlled trial.
Alzheimers Dement. 2024 Mar 13. doi: 10.1002/alz.13766.
PubMed Abstract available

GARCIA-AGUDO LF, Shi Z, Smith IF, Kramar EA, et al
BIN1(K358R) suppresses glial response to plaques in mouse model of Alzheimer's disease.
Alzheimers Dement. 2024 Mar 9. doi: 10.1002/alz.13767.
PubMed Abstract available

MAESTRE G, Hill C, Griffin P, Hall S, et al
Promoting diverse perspectives: Addressing health disparities related to Alzheimer's and all dementias.
Alzheimers Dement. 2024 Mar 9. doi: 10.1002/alz.13752.
PubMed Abstract available

SEPULVEDA-FALLA D, Velez JI, Acosta-Baena N, Baena A, et al
Genetic modifiers of cognitive decline in PSEN1 E280A Alzheimer's disease.
Alzheimers Dement. 2024 Mar 7. doi: 10.1002/alz.13754.
PubMed Abstract available

DEMARCO ML, Algeciras-Schimnich A, Budelier MM
Blood tests for Alzheimer's disease: The impact of disease prevalence on test performance.
Alzheimers Dement. 2024 Mar 6. doi: 10.1002/alz.13762.
PubMed

SONI N, Hohsfield LA, Tran KM, Kawauchi S, et al
Genetic diversity promotes resilience in a mouse model of Alzheimer's disease.
Alzheimers Dement. 2024 Mar 1. doi: 10.1002/alz.13753.
PubMed Abstract available

CHEN K, Ghisays V, Luo J, Chen Y, et al
Harmonizing florbetapir and PiB PET measurements of cortical Abeta plaque burden using multiple regions-of-interest and machine learning techniques: An alternative to the Centiloid approach.
Alzheimers Dement. 2024;20:2165-2172.
PubMed Abstract available

ALDECOA I, Barroeta I, Carroll SL, Fortea J, et al
Down Syndrome Biobank Consortium: A perspective.
Alzheimers Dement. 2024;20:2262-2272.
PubMed Abstract available

JACK CR JR, Wiste HJ, Algeciras-Schimnich A, Weigand SD, et al
Comparison of plasma biomarkers and amyloid PET for predicting memory decline in cognitively unimpaired individuals.
Alzheimers Dement. 2024;20:2143-2154.
PubMed Abstract available

WILKS H, Benzinger TLS, Schindler SE, Cruchaga C, et al
Predictors and outcomes of fluctuations in the clinical dementia rating scale.
Alzheimers Dement. 2024;20:2080-2088.
PubMed Abstract available

ZHOU L, Nguyen TD, Chiang GC, Wang XH, et al
Parenchymal CSF fraction is a measure of brain glymphatic clearance and positively associated with amyloid beta deposition on PET.
Alzheimers Dement. 2024;20:2047-2057.
PubMed Abstract available

SEXTON CE, Bitan G, Bowles KR, Brys M, et al
Novel avenues of tau research.
Alzheimers Dement. 2024;20:2240-2261.
PubMed Abstract available

ROBINSON CG, Lee J, Min PH, Przybelski SA, et al
Significance of a positive tau PET scan with a negative amyloid PET scan.
Alzheimers Dement. 2024;20:1923-1932.
PubMed Abstract available

SATIZABAL CL, Beiser AS, Fletcher E, Seshadri S, et al
A novel neuroimaging signature for ADRD risk stratification in the community.
Alzheimers Dement. 2024;20:1881-1893.
PubMed Abstract available

MOONEN JEF, Haan R, Bos I, Teunissen C, et al
Contributions of amyloid beta and cerebral small vessel disease in clinical decline.
Alzheimers Dement. 2024;20:1868-1880.
PubMed Abstract available

RIVIERE ME, Langbaum JB, Turner RS, Rinne JO, et al
Effects of the active amyloid beta immunotherapy CAD106 on PET measurements of amyloid plaque deposition in cognitively unimpaired APOE epsilon4 homozygotes.
Alzheimers Dement. 2024;20:1839-1850.
PubMed Abstract available

OLTRA J, Habich A, Schwarz CG, Nedelska Z, et al
Sex differences in brain atrophy in dementia with Lewy bodies.
Alzheimers Dement. 2024;20:1815-1826.
PubMed Abstract available

CHEN Y, Spina S, Callahan P, Grinberg LT, et al
Pathology-specific patterns of cerebellar atrophy in neurodegenerative disorders.
Alzheimers Dement. 2024;20:1771-1783.
PubMed Abstract available

SANCHEZ E, Wilkinson T, Coughlan G, Mirza S, et al
Association of plasma biomarkers with cognition, cognitive decline, and daily function across and within neurodegenerative diseases: Results from the Ontario Neurodegenerative Disease Research Initiative.
Alzheimers Dement. 2024;20:1753-1770.
PubMed Abstract available

SUN X, Eastman G, Shi Y, Saibaba S, et al
Structural and functional damage to neuronal nuclei caused by extracellular tau oligomers.
Alzheimers Dement. 2024;20:1656-1670.
PubMed Abstract available

KOTAH JM, Kater MSJ, Brosens N, Lesuis SL, et al
Early-life stress and amyloidosis in mice share pathogenic pathways involving synaptic mitochondria and lipid metabolism.
Alzheimers Dement. 2024;20:1637-1655.
PubMed Abstract available

ROYALL DR, Palmer RF
Statin use moderates APOE's and CRP's associations with dementia and is associated with lesser dementia severity in epsilon4 carriers.
Alzheimers Dement. 2024;20:1627-1636.
PubMed Abstract available

STITES SD, Largent EA, Schumann R, Harkins K, et al
How reactions to a brain scan result differ for adults based on self-identified Black and White race.
Alzheimers Dement. 2024;20:1527-1537.
PubMed Abstract available

ROYSE SK, Snitz BE, Hengenius JB, Huppert TJ, et al
Unhealthy white matter connectivity, cognition, and racialization in older adults.
Alzheimers Dement. 2024;20:1483-1496.
PubMed Abstract available

February 2024

RUTHIRAKUHAN M, Swardfager W, Xiong L, MacIntosh BJ, et al
Investigating the impact of hypertension with and without diabetes on Alzheimer's disease risk: A clinico-pathological study.
Alzheimers Dement. 2024 Feb 29. doi: 10.1002/alz.13717.
PubMed Abstract available

NEWTON C, Pope M, Rua C, Henson R, et al
Entorhinal-based path integration selectively predicts midlife risk of Alzheimer's disease.
Alzheimers Dement. 2024 Feb 29. doi: 10.1002/alz.13733.
PubMed Abstract available

MOHS RC, Beauregard D, Dwyer J, Gaudioso J, et al
The Bio-Hermes Study: Biomarker database developed to investigate blood-based and digital biomarkers in community-based, diverse populations clinically screened for Alzheimer's disease.
Alzheimers Dement. 2024 Feb 28. doi: 10.1002/alz.13722.
PubMed Abstract available

SHIM KH, Kim D, Kang MJ, Pyun JM, et al
Subsequent correlated changes in complement component 3 and amyloid beta oligomers in the blood of patients with Alzheimer's disease.
Alzheimers Dement. 2024 Feb 27. doi: 10.1002/alz.13734.
PubMed Abstract available

SASNER M, Onos KD, Territo PR, Sukoff Rizzo SJ, et al
Meeting report of the fifth annual workshop on Principles and Techniques for Improving Preclinical to Clinical Translation in Alzheimer's Disease Research.
Alzheimers Dement. 2024 Feb 24. doi: 10.1002/alz.13742.
PubMed Abstract available

WANG G, Li Y, Xiong C, Benzinger TLS, et al
Examining amyloid reduction as a surrogate endpoint through latent class analysis using clinical trial data for dominantly inherited Alzheimer's disease.
Alzheimers Dement. 2024 Feb 23. doi: 10.1002/alz.13735.
PubMed Abstract available

XICOTA L, Cosentino S, Vardarajan B, Mayeux R, et al
Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.
Alzheimers Dement. 2024 Feb 21. doi: 10.1002/alz.13718.
PubMed Abstract available

WOLTERS FJ, Labrecque JA
Potential impact of unblinding on observed treatment effects in Alzheimer's disease trials.
Alzheimers Dement. 2024 Feb 21. doi: 10.1002/alz.13690.
PubMed Abstract available

FERGUSON CM, Hildebrand S, Godinho BMDC, Buchwald J, et al
Silencing Apoe with divalent-siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease.
Alzheimers Dement. 2024 Feb 20. doi: 10.1002/alz.13703.
PubMed Abstract available

ORTEGA-CRUZ D, Bress KS, Gazula H, Rabano A, et al
Three-dimensional histology reveals dissociable human hippocampal long-axis gradients of Alzheimer's pathology.
Alzheimers Dement. 2024 Feb 18. doi: 10.1002/alz.13695.
PubMed Abstract available

KUMAR A, Scarpa M, Nordberg A
Tracing synaptic loss in Alzheimer's brain with SV2A PET-tracer UCB-J.
Alzheimers Dement. 2024 Feb 16. doi: 10.1002/alz.13720.
PubMed Abstract available

PILLAI JA, Bena J, Tousi B, Rothenberg K, et al
Lewy body pathology modifies risk factors for cerebral amyloid angiopathy when comorbid with Alzheimer's disease pathology.
Alzheimers Dement. 2024 Feb 14. doi: 10.1002/alz.13704.
PubMed Abstract available

PADULA CB, Ball S, Wyman MF, Evans K, et al
INviting Veterans InTo Enrollment in Alzheimer's Disease Research Centers (INVITE-ADRC): An NIA and VA-sponsored initiative to increase veteran participation in aging and dementia research.
Alzheimers Dement. 2024 Feb 13. doi: 10.1002/alz.13725.
PubMed Abstract available

LI Z, Liang D, Ebelt S, Gearing M, et al
Differential DNA methylation in the brain as potential mediator of the association between traffic-related PM(2.5) and neuropathology markers of Alzheimer's disease.
Alzheimers Dement. 2024 Feb 12. doi: 10.1002/alz.13650.
PubMed Abstract available

BENZOW K, Karanjeet K, Oblak AL, Carter GW, et al
Gene replacement-Alzheimer's disease (GR-AD): Modeling the genetics of human dementias in mice.
Alzheimers Dement. 2024 Feb 11. doi: 10.1002/alz.13730.
PubMed Abstract available

DIAZ-GALVAN P, Przybelski SA, Algeciras-Schimnich A, Figdore DJ, et al
Plasma biomarkers of Alzheimer's disease in the continuum of dementia with Lewy bodies.
Alzheimers Dement. 2024 Feb 8. doi: 10.1002/alz.13653.
PubMed Abstract available

GONZALEZ-ORTIZ F, Karikari TK, Blennow K
Analytical and clinical validation of Alzheimer's disease blood biomarkers with a focus on plasma p-tau217.
Alzheimers Dement. 2024 Feb 8. doi: 10.1002/alz.13708.
PubMed Abstract available

TAHA HB
Early detection of subjective cognitive decline and Alzheimer's disease: Analytical validation of a newly developed pT217-tau assay.
Alzheimers Dement. 2024 Feb 8. doi: 10.1002/alz.13707.
PubMed

ABADIR P, Oh E, Chellappa R, Choudhry N, et al
Artificial Intelligence and Technology Collaboratories: Innovating aging research and Alzheimer's care.
Alzheimers Dement. 2024 Feb 7. doi: 10.1002/alz.13710.
PubMed Abstract available

ZHONG H, Zhou X, Uhm H, Jiang Y, et al
Using blood transcriptome analysis for Alzheimer's disease diagnosis and patient stratification.
Alzheimers Dement. 2024 Feb 7. doi: 10.1002/alz.13691.
PubMed Abstract available

BELLOMO G, Bayoumy S, Megaro A, Toja A, et al
Fully automated measurement of plasma Abeta42/40 and p-tau181: Analytical robustness and concordance with cerebrospinal fluid profile along the Alzheimer's disease continuum in two independent cohorts.
Alzheimers Dement. 2024 Feb 7. doi: 10.1002/alz.13687.
PubMed Abstract available

BELLOMO G, Toja A, Paolini Paoletti F, Ma Y, et al
Investigating alpha-synuclein co-pathology in Alzheimer's disease by means of cerebrospinal fluid alpha-synuclein seed amplification assay.
Alzheimers Dement. 2024 Feb 7. doi: 10.1002/alz.13658.
PubMed Abstract available

GRIFFIN JM, Kim K, Finnie DM, Lapid MI, et al
Developing and describing a typology of lucid episodes among people with Alzheimer's disease and related dementias.
Alzheimers Dement. 2024 Feb 2. doi: 10.1002/alz.13667.
PubMed Abstract available

SHAABAN CE, Lin HS, Terry M, Ren D, et al
COVID-19 pandemic's relationship with enrollment at US Alzheimer's Disease Research Centers.
Alzheimers Dement. 2024 Feb 1. doi: 10.1002/alz.13706.
PubMed Abstract available

ROSSANO SM, Johnson AS, Smith A, Ziaggi G, et al
Microglia measured by TSPO PET are associated with Alzheimer's disease pathology and mediate key steps in a disease progression model.
Alzheimers Dement. 2024 Feb 1. doi: 10.1002/alz.13699.
PubMed Abstract available

Alzheimer's Association and ASNR announce recipients of imaging grants.
Alzheimers Dement. 2024;20:1476-1477.
PubMed

CLARK AL, Thomas KR, Ortega N, Haley AP, et al
Empirically derived psychosocial-behavioral phenotypes in Black/African American and Hispanic/Latino older adults enrolled in HABS-HD: Associations with AD biomarkers and cognitive outcomes.
Alzheimers Dement. 2024;20:1360-1373.
PubMed Abstract available

EISSMAN JM, Archer DB, Mukherjee S, Lee ML, et al
Sex-specific genetic architecture of late-life memory performance.
Alzheimers Dement. 2024;20:1250-1267.
PubMed Abstract available

SLEE MG, Rainey-Smith SR, Villemagne VL, Doecke JD, et al
Physical activity and brain amyloid beta: A longitudinal analysis of cognitively unimpaired older adults.
Alzheimers Dement. 2024;20:1350-1359.
PubMed Abstract available

COGSWELL PM, Lundt ES, Therneau TM, Wiste HJ, et al
Modeling the temporal evolution of plasma p-tau in relation to amyloid beta and tau PET.
Alzheimers Dement. 2024;20:1225-1238.
PubMed Abstract available

BUTTS B, Huang H, Hu WT, Kehoe PG, et al
sPDGFRbeta and neuroinflammation are associated with AD biomarkers and differ by race: The ASCEND Study.
Alzheimers Dement. 2024;20:1175-1189.
PubMed Abstract available

CHEN H, Dunk MM, Wang B, Zhao M, et al
Associations of the Mediterranean-DASH Intervention for Neurodegenerative Delay diet with brain structural markers and their changes.
Alzheimers Dement. 2024;20:1190-1200.
PubMed Abstract available

WOO MS, Tissot C, Lantero-Rodriguez J, Snellman A, et al
Plasma pTau-217 and N-terminal tau (NTA) enhance sensitivity to identify tau PET positivity in amyloid-beta positive individuals.
Alzheimers Dement. 2024;20:1166-1174.
PubMed Abstract available

ACKLEY SF, Wang J, Chen R, Power MC, et al
Estimated effects of amyloid reduction on cognitive change: A Bayesian update across a range of priors.
Alzheimers Dement. 2024;20:1149-1155.
PubMed Abstract available

SANFORD SAI, Miller LVC, Vaysburd M, Keeling S, et al
The type-I interferon response potentiates seeded tau aggregation and exacerbates tau pathology.
Alzheimers Dement. 2024;20:1013-1025.
PubMed Abstract available

GERMAN-CASTELAN L, Shanks HRC, Gros R, Saito T, et al
Sex-dependent cholinergic effects on amyloid pathology: A translational study.
Alzheimers Dement. 2024;20:995-1012.
PubMed Abstract available

SCHWEITZER N, Li J, Thurston RC, Lopresti B, et al
Sex-dependent alterations in hippocampal connectivity are linked to cerebrovascular and amyloid pathologies in normal aging.
Alzheimers Dement. 2024;20:914-924.
PubMed Abstract available

AARONSON A, Ashford MT, Jin C, Bride J, et al
Brain Health Registry Study Partner Portal: Novel infrastructure for digital, dyadic data collection.
Alzheimers Dement. 2024;20:846-857.
PubMed Abstract available

MARINO C, Perez-Corredor P, O'Hare M, Heuer A, et al
APOE Christchurch-mimetic therapeutic antibody reduces APOE-mediated toxicity and tau phosphorylation.
Alzheimers Dement. 2024;20:819-836.
PubMed Abstract available

TATE AE, Bouteloup V, van Maurik IS, Jean D, et al
Predicting sojourn times across dementia disease stages, institutionalization, and mortality.
Alzheimers Dement. 2024;20:809-818.
PubMed Abstract available

January 2024

DAMSGAARD L, Janbek J, Laursen TM, Hogh P, et al
Mapping morbidity 10 years prior to a diagnosis of young onset Alzheimer's disease.
Alzheimers Dement. 2024 Jan 31. doi: 10.1002/alz.13681.
PubMed Abstract available

Withdrawal: Glycine transporter 1 (GlyT1) is a novel therapeutic target for Alzheimer's disease.
Alzheimers Dement. 2024 Jan 31. doi: 10.1002/alz.13724.
PubMed Abstract available

ALGECIRAS-SCHIMNICH A, Bornhorst JA
Importance of cerebrospinal fluid (CSF) collection protocol for the accurate diagnosis of Alzheimer's disease when using CSF biomarkers.
Alzheimers Dement. 2024 Jan 30. doi: 10.1002/alz.13721.
PubMed

HUBER H, Blennow K, Zetterberg H, Boada M, et al
Biomarkers of Alzheimer's disease and neurodegeneration in dried blood spots-A new collection method for remote settings.
Alzheimers Dement. 2024 Jan 29. doi: 10.1002/alz.13697.
PubMed Abstract available

GOMEZ-ARBOLEDAS A, Fonseca MI, Kramar E, Chu SH, et al
C5aR1 signaling promotes region- and age-dependent synaptic pruning in models of Alzheimer's disease.
Alzheimers Dement. 2024 Jan 26. doi: 10.1002/alz.13682.
PubMed Abstract available

RUBINSTEIN T, Brickman AM, Cheng B, Burkett S, et al
Periodontitis and brain magnetic resonance imaging markers of Alzheimer's disease and cognitive aging.
Alzheimers Dement. 2024 Jan 26. doi: 10.1002/alz.13683.
PubMed Abstract available

DEECKE L, Homann J, Goldecktble D, Ohlei O, et al
No increase of CD8+ TEMRA cells in the blood of healthy adults at high genetic risk of Alzheimer's disease.
Alzheimers Dement. 2024 Jan 25. doi: 10.1002/alz.13709.
PubMed

XU H, Bayless TM, Ostbye T, Dupre ME, et al
Care sequences leading to the diagnosis of Alzheimer's disease and related dementias: An analysis of electronic health records.
Alzheimers Dement. 2024 Jan 25. doi: 10.1002/alz.13669.
PubMed Abstract available

LANDAU SM, Lee J, Murphy A, Ward TJ, et al
Individuals with Alzheimer's disease and low tau burden: Characteristics and implications.
Alzheimers Dement. 2024 Jan 19. doi: 10.1002/alz.13609.
PubMed Abstract available

TSOY E, La Joie R, VandeVrede L, Rojas JC, et al
Scalable plasma and digital cognitive markers for diagnosis and prognosis of Alzheimer's disease and related dementias.
Alzheimers Dement. 2024 Jan 15. doi: 10.1002/alz.13686.
PubMed Abstract available

POMARA N, Imbimbo BP
Do anti-Abeta monoclonal antibodies lower brain plaques in Alzheimer patients through microglia activation?
Alzheimers Dement. 2024 Jan 15. doi: 10.1002/alz.13684.
PubMed

HATA Y, Nakase M, Ichimata S, Yoshida K, et al
Neuropathology of patients with preclinical or early clinical Alzheimer's disease with pathogenic PSEN1_p. L392V: Comparison of advanced siblings.
Alzheimers Dement. 2024 Jan 12. doi: 10.1002/alz.13675.
PubMed Abstract available

SUCHY-DICEY AM, Longstreth WT Jr, Rhoads K, Umans J, et al
Plasma biomarkers of Alzheimer's disease and related dementias in American Indians: The Strong Heart Study.
Alzheimers Dement. 2024 Jan 12. doi: 10.1002/alz.13664.
PubMed Abstract available

HO PC, Yu WH, Tee BL, Lee WP, et al
Asian Cohort for Alzheimer's Disease (ACAD) pilot study on genetic and non-genetic risk factors for Alzheimer's disease among Asian Americans and Canadians.
Alzheimers Dement. 2024 Jan 12. doi: 10.1002/alz.13611.
PubMed Abstract available

OWENS HA, Thorburn LE, Walsby E, Moon OR, et al
Alzheimer's disease-associated P460L variant of EphA1 dysregulates receptor activity and blood-brain barrier function.
Alzheimers Dement. 2024 Jan 7. doi: 10.1002/alz.13603.
PubMed Abstract available

WANG P, Lynn A, Miskimen K, Song YE, et al
Genome-wide association studies identify novel loci in rapidly progressive Alzheimer's disease.
Alzheimers Dement. 2024 Jan 7. doi: 10.1002/alz.13655.
PubMed Abstract available

BUTO PT, Wang J, La Joie R, Zimmerman SC, et al
Genetic risk score for Alzheimer's disease predicts brain volume differences in mid and late life in UK biobank participants.
Alzheimers Dement. 2024 Jan 6. doi: 10.1002/alz.13610.
PubMed Abstract available

GU Y, Honig LS, Kang MS, Bahl A, et al
Risk of Alzheimer's disease is associated with longitudinal changes in plasma biomarkers in the multi-ethnic Washington Heights-Hamilton Heights-Inwood Columbia Aging Project (WHICAP) cohort.
Alzheimers Dement. 2024 Jan 6. doi: 10.1002/alz.13652.
PubMed Abstract available

JIANG Y, Uhm H, Ip FC, Ouyang L, et al
A blood-based multi-pathway biomarker assay for early detection and staging of Alzheimer's disease across ethnic groups.
Alzheimers Dement. 2024 Jan 6. doi: 10.1002/alz.13676.
PubMed Abstract available

SRIKRISHNA M, Ashton NJ, Moscoso A, Pereira JB, et al
CT-based volumetric measures obtained through deep learning: Association with biomarkers of neurodegeneration.
Alzheimers Dement. 2024;20:629-640.
PubMed Abstract available

JAIN L, Khrestian M, Formica S, Tuason ED, et al
ATN cerebrospinal fluid biomarkers in dementia with Lewy bodies: Initial results from the United States Dementia with Lewy Bodies Consortium.
Alzheimers Dement. 2024;20:549-562.
PubMed Abstract available

LOPES KP, Yu L, Shen X, Qiu Y, et al
Associations of cortical SPP1 and ITGAX with cognition and common neuropathologies in older adults.
Alzheimers Dement. 2024;20:525-537.
PubMed Abstract available

MADSEN LS, Kjeldsen PL, Ismail R, Parbo P, et al
Capillary dysfunction in healthy elderly APOE epsilon4 carriers with raised brain Abeta deposition.
Alzheimers Dement. 2024;20:459-471.
PubMed Abstract available

LIU W, Yu L, Deng Q, Li Y, et al
Toward digitally screening and profiling AD: A GAMLSS approach of MemTrax in China.
Alzheimers Dement. 2024;20:399-409.
PubMed Abstract available

ZAMMIT MD, Betthauser TJ, McVea AK, Laymon CM, et al
Characterizing the emergence of amyloid and tau burden in Down syndrome.
Alzheimers Dement. 2024;20:388-398.
PubMed Abstract available

WANG X, Sundermann EE, Buckley RF, Banks SJ, et al
Sex differences in the association between tau PET and cognitive performance in a non-Hispanic White cohort with preclinical AD.
Alzheimers Dement. 2024;20:25-33.
PubMed Abstract available

SALONER R, VandeVrede L, Asken BM, Paolillo EW, et al
Plasma phosphorylated tau-217 exhibits sex-specific prognostication of cognitive decline and brain atrophy in cognitively unimpaired adults.
Alzheimers Dement. 2024;20:376-387.
PubMed Abstract available

WALKIEWICZ G, Ronisz A, Van Ginderdeuren R, Lemmens S, et al
Primary retinal tauopathy: A tauopathy with a distinct molecular pattern.
Alzheimers Dement. 2024;20:330-340.
PubMed Abstract available

PEZZOLI S, Giorgio J, Martersteck A, Dobyns L, et al
Successful cognitive aging is associated with thicker anterior cingulate cortex and lower tau deposition compared to typical aging.
Alzheimers Dement. 2024;20:341-355.
PubMed Abstract available

GAUTHREAUX K, Kukull WA, Nelson KB, Mock C, et al
Different cohort, disparate results: Selection bias is a key factor in autopsy cohorts.
Alzheimers Dement. 2024;20:266-277.
PubMed Abstract available

TITCOMB TJ, Richey P, Casanova R, Phillips LS, et al
Association of type 2 diabetes mellitus with dementia-related and non-dementia-related mortality among postmenopausal women: A secondary competing risks analysis of the women's health initiative.
Alzheimers Dement. 2024;20:234-242.
PubMed Abstract available

BOCCALINI C, Ribaldi F, Hristovska I, Arnone A, et al
The impact of tau deposition and hypometabolism on cognitive impairment and longitudinal cognitive decline.
Alzheimers Dement. 2024;20:221-233.
PubMed Abstract available

VAN DER HEIDE FCT, Khawaja A, Berendschot TTJM, Littlejohns TJ, et al
Associations of inner retinal layers with risk of incident dementia: An individual participant data analysis of four prospective cohort studies.
Alzheimers Dement. 2024;20:211-220.
PubMed Abstract available

HARDY CJD, Taylor-Rubin C, Taylor B, Harding E, et al
Symptom-led staging for semantic and non-fluent/agrammatic variants of primary progressive aphasia.
Alzheimers Dement. 2024;20:195-210.
PubMed Abstract available

WANG X, St George RJ, Bindoff AD, Noyce AJ, et al
Estimating presymptomatic episodic memory impairment using simple hand movement tests: A cross-sectional study of a large sample of older adults.
Alzheimers Dement. 2024;20:173-182.
PubMed Abstract available

CAMINITI SP, De Francesco S, Tondo G, Galli A, et al
FDG-PET markers of heterogeneity and different risk of progression in amnestic MCI.
Alzheimers Dement. 2024;20:159-172.
PubMed Abstract available

DENG J, Sun B, Kavcic V, Liu M, et al
Novel methodology for detection and prediction of mild cognitive impairment using resting-state EEG.
Alzheimers Dement. 2024;20:145-158.
PubMed Abstract available

December 2023

LU Y, Pike JR, Hoogeveen RC, Walker KA, et al
Liver integrity and the risk of Alzheimer's disease and related dementias.
Alzheimers Dement. 2023 Dec 28. doi: 10.1002/alz.13601.
PubMed Abstract available

DARRICAU M, Dou C, Kinet R, Zhu T, et al
Tau seeds from Alzheimer's disease brains trigger tau spread in macaques while oligomeric-Abeta mediates pathology maturation.
Alzheimers Dement. 2023 Dec 26. doi: 10.1002/alz.13604.
PubMed Abstract available

ABIOSE O, Rutledge J, Moran-Losada P, Belloy ME, et al
Post-translational modifications linked to preclinical Alzheimer's disease-related pathological and cognitive changes.
Alzheimers Dement. 2023 Dec 25. doi: 10.1002/alz.13576.
PubMed Abstract available

Correction to "Strain hypothesis and additional evidence of the GluN3A deficiency? mediated pathogenesis of Alzheimer's disease".
Alzheimers Dement. 2023 Dec 21. doi: 10.1002/alz.13549.
PubMed

WANG X, Bakulski KM, Karvonen-Gutierrez CA, Park SK, et al
Blood-based biomarkers for Alzheimer's disease and cognitive function from mid- to late life.
Alzheimers Dement. 2023 Dec 21. doi: 10.1002/alz.13583.
PubMed Abstract available

ASLANYAN V, Mack WJ, Ortega NE, Nasrallah IM, et al
Cerebrovascular reactivity in Alzheimer's disease signature regions is associated with mild cognitive impairment in adults with hypertension.
Alzheimers Dement. 2023 Dec 18. doi: 10.1002/alz.13572.
PubMed Abstract available

CRANE PK, Groot C, Ossenkoppele R, Mukherjee S, et al
Cognitively defined Alzheimer's dementia subgroups have distinct atrophy patterns.
Alzheimers Dement. 2023 Dec 13. doi: 10.1002/alz.13567.
PubMed Abstract available

DOUROS A, Ante Z, Fallone CA, Azoulay L, et al
Clinically apparent Helicobacter pylori infection and the risk of incident Alzheimer's disease: A population-based nested case-control study.
Alzheimers Dement. 2023 Dec 13. doi: 10.1002/alz.13561.
PubMed Abstract available

VILOR-TEJEDOR N, Genius P, Rodriguez-Fernandez B, Minguillon C, et al
Genetic characterization of the ALFA study: Uncovering genetic profiles in the Alzheimer's continuum.
Alzheimers Dement. 2023 Dec 13. doi: 10.1002/alz.13537.
PubMed Abstract available

DEVANARAYAN V, Ye Y, Charil A, Andreozzi E, et al
Predicting clinical progression trajectories of early Alzheimer's disease patients.
Alzheimers Dement. 2023 Dec 13. doi: 10.1002/alz.13565.
PubMed Abstract available

MORGAN DG, Lamb BT
Transgenic amyloid precursor protein mouse models of amyloidosis. Incomplete models for Alzheimer's disease but effective predictors of anti-amyloid therapies.
Alzheimers Dement. 2023 Dec 12. doi: 10.1002/alz.13566.
PubMed Abstract available

CONNIFF KR, Grill JD, Gillen DL
Retention of American Indian and Alaska Native participants in the National Alzheimer's Coordinating Center Uniform Data Set.
Alzheimers Dement. 2023 Dec 5. doi: 10.1002/alz.13573.
PubMed Abstract available

AMANO T, Halvorsen CJ, Kim S, Reynolds A, et al
An outcome-wide analysis of the effects of diagnostic labeling of Alzheimer's disease and related dementias on social relationships.
Alzheimers Dement. 2023 Dec 5. doi: 10.1002/alz.13574.
PubMed Abstract available

LYU X, Duong MT, Xie L, de Flores R, et al
Tau-neurodegeneration mismatch reveals vulnerability and resilience to comorbidities in Alzheimer's continuum.
Alzheimers Dement. 2023 Dec 5. doi: 10.1002/alz.13559.
PubMed Abstract available

BELLIER JP, Cai Y, Alam SM, Wiederhold T, et al
Uncovering elevated tau TPP motif phosphorylation in the brain of Alzheimer's disease patients.
Alzheimers Dement. 2023 Dec 2. doi: 10.1002/alz.13557.
PubMed Abstract available

LE BORGNE J, Amouyel P, Andreassen O, Frikke-Schmidt R, et al
Association of MGMT and BIN1 genes with Alzheimer's disease risk across sex and APOE epsilon4 status.
Alzheimers Dement. 2023 Dec 2. doi: 10.1002/alz.13550.
PubMed

REN Y, Li Y, Tian N, Liu R, et al
Multimorbidity, cognitive phenotypes, and Alzheimer's disease plasma biomarkers in older adults: A population-based study.
Alzheimers Dement. 2023 Dec 2. doi: 10.1002/alz.13519.
PubMed Abstract available

BETTENCOURT C, Skene N, Bandres-Ciga S, Anderson E, et al
Artificial intelligence for dementia genetics and omics.
Alzheimers Dement. 2023;19:5905-5921.
PubMed Abstract available

BORCHERT RJ, Azevedo T, Badhwar A, Bernal J, et al
Artificial intelligence for diagnostic and prognostic neuroimaging in dementia: A systematic review.
Alzheimers Dement. 2023;19:5885-5904.
PubMed Abstract available

STERN AM, Van Pelt KL, Liu L, Anderson AK, et al
Plasma NT1-tau and Abeta(42) correlate with age and cognitive function in two large Down syndrome cohorts.
Alzheimers Dement. 2023;19:5755-5764.
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LEE YG, Jeon S, Kang SW, Ye BS, et al
Effects of amyloid beta and dopaminergic depletion on perfusion and clinical symptoms.
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GRASSET L, Planche V, Bouteloup V, Azouani C, et al
Physical activity, biomarkers of brain pathologies and dementia risk: Results from the Memento clinical cohort.
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GERICKE C, Kirabali T, Flury R, Mallone A, et al
Early beta-amyloid accumulation in the brain is associated with peripheral T cell alterations.
Alzheimers Dement. 2023;19:5642-5662.
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NGUYEN HO PT, van Arendonk J, Steketee RME, van Rooij FJA, et al
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Alzheimers Dement. 2023;19:5506-5517.
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TOSUN D, Thropp P, Southekal S, Spottiswoode B, et al
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FRANZEN S, Nuytemans K, Bourdage R, Caramelli P, et al
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JAHREIS K, Bruge A, Borsdorf S, Muller FE, et al
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KIM KY, Ha J, Lee JY, Kim E, et al
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STANKEVICIUTE L, Falcon C, Operto G, Garcia M, et al
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LANTERO-RODRIGUEZ J, Tissot C, Snellman A, Servaes S, et al
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PILONIETA G, Geldmacher DS
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BARBONE JM, Khurshid K, Edgar CJ, Maruff P, et al
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November 2023

CHUMIN EJ, Burton CP, Silvola R, Miner EW, et al
Brain metabolic network covariance and aging in a mouse model of Alzheimer's disease.
Alzheimers Dement. 2023 Nov 30. doi: 10.1002/alz.13538.
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FOLEY KE, Winder Z, Sudduth TL, Martin BJ, et al
Alzheimer's disease and inflammatory biomarkers positively correlate in plasma in the UK-ADRC cohort.
Alzheimers Dement. 2023 Nov 27. doi: 10.1002/alz.13485.
PubMed Abstract available

DALMASSO MC, de Rojas I, Olivar N, Muchnik C, et al
The first genome-wide association study in the Argentinian and Chilean populations identifies shared genetics with Europeans in Alzheimer's disease.
Alzheimers Dement. 2023 Nov 20. doi: 10.1002/alz.13522.
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HOU Y, Caldwell JZK, Lathia JD, Leverenz JB, et al
Microglial immunometabolism endophenotypes contribute to sex difference in Alzheimer's disease.
Alzheimers Dement. 2023 Nov 20. doi: 10.1002/alz.13546.
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BRUM WS, Ashton NJ, Simren J, di Molfetta G, et al
Biological variation estimates of Alzheimer's disease plasma biomarkers in healthy individuals.
Alzheimers Dement. 2023 Nov 20. doi: 10.1002/alz.13518.
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ARCHER DB, Eissman JM, Mukherjee S, Lee ML, et al
Longitudinal change in memory performance as a strong endophenotype for Alzheimer's disease.
Alzheimers Dement. 2023 Nov 20. doi: 10.1002/alz.13508.
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GONZALEZ-ORTIZ F, Ferreira PCL, Gonzalez-Escalante A, Montoliu-Gaya L, et al
A novel ultrasensitive assay for plasma p-tau217: Performance in individuals with subjective cognitive decline and early Alzheimer's disease.
Alzheimers Dement. 2023 Nov 17. doi: 10.1002/alz.13525.
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POWELL WR, Vilen L, Zuelsdorff M, Goutman SA, et al
Association between military service and Alzheimer's disease neuropathology at autopsy.
Alzheimers Dement. 2023 Nov 15. doi: 10.1002/alz.13520.
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RISSMAN RA, Langford O, Raman R, Donohue MC, et al
Plasma Abeta42/Abeta40 and phospho-tau217 concentration ratios increase the accuracy of amyloid PET classification in preclinical Alzheimer's disease.
Alzheimers Dement. 2023 Nov 6. doi: 10.1002/alz.13542.
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ALBER J, Bouwman F, den Haan J, Rissman RA, et al
Retina pathology as a target for biomarkers for Alzheimer's disease: Current status, ophthalmopathological background, challenges, and future directions.
Alzheimers Dement. 2023 Nov 2. doi: 10.1002/alz.13529.
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CANEPA E, Parodi-Rullan R, Vazquez-Torres R, Gamallo-Lana B, et al
FDA-approved carbonic anhydrase inhibitors reduce amyloid beta pathology and improve cognition, by ameliorating cerebrovascular health and glial fitness.
Alzheimers Dement. 2023;19:5048-5073.
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HAUSMANN A, Chiabotti PS, Nasuti M, Rouaud O, et al
Don't forget primary progressive aphasia for anti-amyloid drugs: An estimation of eligible patients from the Lausanne Memory Center registry.
Alzheimers Dement. 2023;19:5303-5304.
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JIANG X, Hu X, Daamen M, Wang X, et al
Altered limbic functional connectivity in individuals with subjective cognitive decline: Converging and diverging findings across Chinese and German cohorts.
Alzheimers Dement. 2023;19:4922-4934.
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OECKL P, Bluma M, Bucci M, Halbgebauer S, et al
Blood beta-synuclein is related to amyloid PET positivity in memory clinic patients.
Alzheimers Dement. 2023;19:4896-4907.
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MALEKI BALAJOO S, Eickhoff SB, Masouleh SK, Plachti A, et al
Hippocampal metabolic subregions and networks: Behavioral, molecular, and pathological aging profiles.
Alzheimers Dement. 2023;19:4787-4804.
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WILCOCK DM
The longitudinal early-onset Alzheimer's disease study (LEADS): Advancing our understanding of Alzheimer's disease in individuals aged 40-64.
Alzheimers Dement. 2023;19 Suppl 9:S7.
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ORTEGA-CRUZ D, Iglesias JE, Rabano A, Strange BA, et al
Hippocampal sclerosis of aging at post-mortem is evident on MRI more than a decade prior.
Alzheimers Dement. 2023;19:5307-5315.
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FREEZE WM, Van Veluw SJ, Jansen WJ, Bennett DA, et al
Locus coeruleus pathology is associated with cerebral microangiopathy at autopsy.
Alzheimers Dement. 2023;19:5023-5035.
PubMed Abstract available

ZHANG M, Ganz AB, Rohde S, Lorenz L, et al
The correlation between neuropathology levels and cognitive performance in centenarians.
Alzheimers Dement. 2023;19:5036-5047.
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CAI Y, Fan X, Zhao L, Liu W, et al
Comparing machine learning-derived MRI-based and blood-based neurodegeneration biomarkers in predicting syndromal conversion in early AD.
Alzheimers Dement. 2023;19:4987-4998.
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WEINER MW, Aaronson A, Eichenbaum J, Kwang W, et al
Brain health registry updates: An online longitudinal neuroscience platform.
Alzheimers Dement. 2023;19:4935-4951.
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SHI H, Koronyo Y, Fuchs DT, Sheyn J, et al
Retinal arterial Abeta(40) deposition is linked with tight junction loss and cerebral amyloid angiopathy in MCI and AD patients.
Alzheimers Dement. 2023;19:5185-5197.
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October 2023

MUIR RT, Ismail Z, Black SE, Smith EE, et al
Comparative methods for quantifying plasma biomarkers in Alzheimer's disease: Implications for the next frontier in cerebral amyloid angiopathy diagnostics.
Alzheimers Dement. 2023 Oct 31. doi: 10.1002/alz.13510.
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KELLY L, Brown C, Michalik D, Hawkes CA, et al
Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA), updates in 2022-2023. Cerebrovascular disease and the failure of elimination of Amyloid-beta from the brain and retina with age and Alzheimer
Alzheimers Dement. 2023 Oct 28. doi: 10.1002/alz.13512.
PubMed Abstract available

PANG M, Gabelle A, Saha-Chaudhuri P, Huijbers W, et al
Precision medicine analysis of heterogeneity in individual-level treatment response to amyloid beta removal in early Alzheimer's disease.
Alzheimers Dement. 2023 Oct 26. doi: 10.1002/alz.13431.
PubMed Abstract available

FERRETTI MT, Ding H, Au R, Liu C, et al
Maximizing utility of neuropsychological measures in sex-specific predictive models of incident Alzheimer's disease in the Framingham Heart Study.
Alzheimers Dement. 2023 Oct 26. doi: 10.1002/alz.13500.
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GREENFEST-ALLEN E, Valladares O, Kuksa PP, Gangadharan P, et al
NIAGADS Alzheimer's GenomicsDB: A resource for exploring Alzheimer's disease genetic and genomic knowledge.
Alzheimers Dement. 2023 Oct 26. doi: 10.1002/alz.13509.
PubMed Abstract available

GONZALEZ-ORTIZ F, Karikari TK, Bentivenga GM, Baiardi S, et al
Levels of plasma brain-derived tau and p-tau181 in Alzheimer's disease and rapidly progressive dementias.
Alzheimers Dement. 2023 Oct 19. doi: 10.1002/alz.13516.
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XU Y, Sun Z, Jonaitis E, Deming Y, et al
Apolipoprotein E moderates the association between non-APOE polygenic risk score for Alzheimer's disease and aging on preclinical cognitive function.
Alzheimers Dement. 2023 Oct 19. doi: 10.1002/alz.13515.
PubMed Abstract available

BREEN C, Papale LA, Clark LR, Bergmann PE, et al
Whole genome methylation sequencing in blood identifies extensive differential DNA methylation in late-onset dementia due to Alzheimer's disease.
Alzheimers Dement. 2023 Oct 19. doi: 10.1002/alz.13514.
PubMed Abstract available

GORIJALA P, Aslam MM, Dang LT, Xicota L, et al
Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome.
Alzheimers Dement. 2023 Oct 19. doi: 10.1002/alz.13506.
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WEI YJ, Winterstein AG, Schmidt S, Fillingim RB, et al
Pain intensity, physical function, and depressive symptoms associated with discontinuing long-term opioid therapy in older adults with Alzheimer's disease and related dementias.
Alzheimers Dement. 2023 Oct 19. doi: 10.1002/alz.13489.
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TOUROUTOGLOU A, Katsumi Y, Brickhouse M, Zaitsev A, et al
The Sporadic Early-onset Alzheimer's Disease Signature Of Atrophy: Preliminary Findings From The Longitudinal Early-onset Alzheimer's Disease Study (LEADS) Cohort.
Alzheimers Dement. 2023 Oct 18. doi: 10.1002/alz.13466.
PubMed Abstract available

LANGELLA S, Lopera F, Baena A, Fox-Fuller JT, et al
Depressive symptoms and hippocampal volume in autosomal dominant Alzheimer's disease.
Alzheimers Dement. 2023 Oct 14. doi: 10.1002/alz.13501.
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SCOYNI F, Giudice L, Vaananen MA, Downes N, et al
Alzheimer's disease-induced phagocytic microglia express a specific profile of coding and non-coding RNAs.
Alzheimers Dement. 2023 Oct 12. doi: 10.1002/alz.13502.
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LI P, Gao L, Dashti HS, Hu K, et al
Authors' response to: A Mendelian randomization study of Alzheimer's disease and daytime napping.
Alzheimers Dement. 2023 Oct 12. doi: 10.1002/alz.13504.
PubMed

RAN S, Lin X, Liu B
A Mendelian randomization study of Alzheimer's disease and daytime napping.
Alzheimers Dement. 2023 Oct 12. doi: 10.1002/alz.13505.
PubMed

FERRANTE FJ, Migeot J, Birba A, Amoruso L, et al
Multivariate word properties in fluency tasks reveal markers of Alzheimer's dementia.
Alzheimers Dement. 2023 Oct 12. doi: 10.1002/alz.13472.
PubMed Abstract available

GAIKWAD S, Senapati S, Haque MA, Kayed R, et al
Senescence, brain inflammation, and oligomeric tau drive cognitive decline in Alzheimer's disease: Evidence from clinical and preclinical studies.
Alzheimers Dement. 2023 Oct 9. doi: 10.1002/alz.13490.
PubMed Abstract available

WANG J, Sims KD, Ackley SF, Chen R, et al
Association of cancer history with structural brain aging markers of Alzheimer's disease and related dementias risk.
Alzheimers Dement. 2023 Oct 9. doi: 10.1002/alz.13497.
PubMed Abstract available

NUDELMAN KNH, Jackson T, Rumbaugh M, Eloyan A, et al
Pathogenic variants in the Longitudinal Early-onset Alzheimer's Disease Study cohort.
Alzheimers Dement. 2023 Oct 6. doi: 10.1002/alz.13482.
PubMed Abstract available

AAIC 2023: Discoveries propel Alzheimer's diagnosis and clinical care.
Alzheimers Dement. 2023 Oct 3. doi: 10.1002/alz.13487.
PubMed

BEYDOUN HA, Beydoun MA, Meirelles O, Erickson LD, et al
Cardiovascular health, infection burden, and incident dementia in the UK Biobank.
Alzheimers Dement. 2023;19:4475-4487.
PubMed Abstract available

GONZALEZ-ORTIZ F, Dias A, Turton M, Magalhaes R, et al
Preanalytical stability of plasma/serum brain-derived tau.
Alzheimers Dement. 2023;19:4764-4770.
PubMed Abstract available

KWON HS, Kim JY, Koh SH, Choi SH, et al
Predicting cognitive stage transition using p-tau181, Centiloid, and other measures.
Alzheimers Dement. 2023;19:4641-4650.
PubMed Abstract available

WANG M, Sajobi TT, Hogan DB, Ganesh A, et al
Expert elicitation of risk factors for progression to dementia in individuals with mild cognitive impairment.
Alzheimers Dement. 2023;19:4542-4548.
PubMed Abstract available

FERREIRA PCL, Therriault J, Tissot C, Ferrari-Souza JP, et al
Plasma p-tau231 and p-tau217 inform on tau tangles aggregation in cognitively impaired individuals.
Alzheimers Dement. 2023;19:4463-4474.
PubMed Abstract available

LITKOWSKI EM, Logue MW, Zhang R, Charest BR, et al
Mendelian randomization study of diabetes and dementia in the Million Veteran Program.
Alzheimers Dement. 2023;19:4367-4376.
PubMed Abstract available

SAMUELSSON J, Marseglia A, Lindberg O, Westman E, et al
Associations between dietary patterns and dementia-related neuroimaging markers.
Alzheimers Dement. 2023;19:4629-4640.
PubMed Abstract available

ADKINS-JACKSON PB, Kraal AZ, Hill-Jarrett TG, George KM, et al
Riding the merry-go-round of racial disparities in ADRD research.
Alzheimers Dement. 2023;19:4735-4742.
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CHAKRABARTY M, Klooster N, Biswas A, Chatterjee A, et al
The scope of using pragmatic language tests for early detection of dementia: A systematic review of investigations using figurative language.
Alzheimers Dement. 2023;19:4705-4728.
PubMed Abstract available

DHANA A, DeCarli CS, Dhana K, Desai P, et al
Cardiovascular health and cognitive outcomes: Findings from a biracial population-based study in the United States.
Alzheimers Dement. 2023;19:4446-4453.
PubMed Abstract available

September 2023

WALKER JM, Orr ME, Orr TC, Thorn EL, et al
Spatial proteomics of hippocampal subfield-specific pathology in Alzheimer's disease and primary age-related tauopathy.
Alzheimers Dement. 2023 Sep 30. doi: 10.1002/alz.13484.
PubMed Abstract available

ERASLAN BOZ H, Kocoglu K, Akkoyun M, Tufekci IY, et al
Visual search in Alzheimer's disease and amnestic mild cognitive impairment: An eye-tracking study.
Alzheimers Dement. 2023 Sep 29. doi: 10.1002/alz.13478.
PubMed Abstract available

ALBALA B, Appelmans E, Burress R, De Santi S, et al
The Alzheimer's Disease Neuroimaging Initiative and the role and contributions of the Private Partners Scientific Board (PPSB).
Alzheimers Dement. 2023 Sep 29. doi: 10.1002/alz.13483.
PubMed Abstract available

HEUER SE, Keezer KJ, Hewes AA, Onos KD, et al
Control of hippocampal synaptic plasticity by microglia-dendrite interactions depends on genetic context in mouse models of Alzheimer's disease.
Alzheimers Dement. 2023 Sep 27. doi: 10.1002/alz.13440.
PubMed Abstract available

WAGEMANN O, Li Y, Hassenstab J, Aschenbrenner AJ, et al
Investigation of sex differences in mutation carriers of the Dominantly Inherited Alzheimer Network.
Alzheimers Dement. 2023 Sep 23. doi: 10.1002/alz.13460.
PubMed Abstract available

MORRISON C, Dadar M, Collins DL
Sex differences in risk factors, burden, and outcomes of cerebrovascular disease in Alzheimer's disease populations.
Alzheimers Dement. 2023 Sep 21. doi: 10.1002/alz.13452.
PubMed Abstract available

BONOMI S, Gupta MR, Schindler SE
Inadequate reimbursement for lumbar puncture is a potential barrier to accessing new Alzheimer's disease treatments.
Alzheimers Dement. 2023 Sep 18. doi: 10.1002/alz.13473.
PubMed

VEITCH DP, Weiner MW, Miller M, Aisen PS, et al
The Alzheimer's Disease Neuroimaging Initiative in the era of Alzheimer's disease treatment: A review of ADNI studies from 2021 to 2022.
Alzheimers Dement. 2023 Sep 12. doi: 10.1002/alz.13449.
PubMed Abstract available

GAUGLER JE, Borson S, Epps F, Shih RA, et al
The intersection of social determinants of health and family care of people living with Alzheimer's disease and related dementias: A public health opportunity.
Alzheimers Dement. 2023 Sep 12. doi: 10.1002/alz.13437.
PubMed Abstract available

CHEN K, Gupta R, Martin-Avila A, Cui M, et al
Anesthesia-induced hippocampal-cortical hyperactivity and tau hyperphosphorylation impair remote memory retrieval in Alzheimer's disease.
Alzheimers Dement. 2023 Sep 11. doi: 10.1002/alz.13464.
PubMed Abstract available

BLENNOW K, Galasko D, Perneczky R, Quevenco FC, et al
The potential clinical value of plasma biomarkers in Alzheimer's disease.
Alzheimers Dement. 2023 Sep 11. doi: 10.1002/alz.13455.
PubMed Abstract available

CHO H, Mundada NS, Apostolova LG, Carrillo MC, et al
Amyloid and tau-PET in early-onset AD: Baseline data from the Longitudinal Early-onset Alzheimer's Disease Study (LEADS).
Alzheimers Dement. 2023 Sep 10. doi: 10.1002/alz.13453.
PubMed Abstract available

PELKMANS W, Shekari M, Brugulat-Serrat A, Sanchez-Benavides G, et al
Astrocyte biomarkers GFAP and YKL-40 mediate early Alzheimer's disease progression.
Alzheimers Dement. 2023 Sep 10. doi: 10.1002/alz.13450.
PubMed Abstract available

ASKEN BM, Wang WE, McFarland K, Arias F, et al
Plasma Alzheimer's biomarkers and brain amyloid in Hispanic and non-Hispanic older adults.
Alzheimers Dement. 2023 Sep 6. doi: 10.1002/alz.13456.
PubMed Abstract available

TOSUN D, Yardibi O, Benzinger TLS, Kukull WA, et al
Identifying individuals with non-Alzheimer's disease co-pathologies: A precision medicine approach to clinical trials in sporadic Alzheimer's disease.
Alzheimers Dement. 2023 Sep 4. doi: 10.1002/alz.13447.
PubMed Abstract available

WOOD KA, Han F, Ko YA, Wharton WW, et al
Is the association between cognitive disease progression and atrial fibrillation modified by sex?
Alzheimers Dement. 2023;19:4163-4173.
PubMed Abstract available

LU J, Liang F, Bai P, Liu C, et al
Blood tau-PT217 contributes to the anesthesia/surgery-induced delirium-like behavior in aged mice.
Alzheimers Dement. 2023;19:4110-4126.
PubMed Abstract available

WEAVER DF
Amyloid-beta is a cytokine.
Alzheimers Dement. 2023;19:4237-4247.
PubMed Abstract available

ROBINSON T, Klinger H, Buckley R, Deters KD, et al
Subjective cognitive decline across ethnoracial groups in the A4 study.
Alzheimers Dement. 2023;19:4084-4093.
PubMed Abstract available

QIANG YX, Deng YT, Zhang YR, Wang HF, et al
Associations of blood cell indices and anemia with risk of incident dementia: A prospective cohort study of 313,448 participants.
Alzheimers Dement. 2023;19:3965-3976.
PubMed Abstract available

MATTKE S, Batie D, Chodosh J, Felten K, et al
Expanding the use of brief cognitive assessments to detect suspected early-stage cognitive impairment in primary care.
Alzheimers Dement. 2023;19:4252-4259.
PubMed Abstract available

OH H, White EM, Muench U, Santostefano C, et al
Advanced practice clinician care and end-of-life outcomes for community- and nursing home-dwelling Medicare beneficiaries with dementia.
Alzheimers Dement. 2023;19:3946-3964.
PubMed Abstract available

BURGDORF JG, Mroz TM, Reckrey JM, Barron Y, et al
Prevalence and predictors of incident ADRD diagnosis following a Medicare home health episode.
Alzheimers Dement. 2023;19:3936-3945.
PubMed Abstract available

NASSAN M, Daghlas I, Piras IS, Rogalski E, et al
Evaluating the association between genetically proxied ACE inhibition and dementias.
Alzheimers Dement. 2023;19:3894-3901.
PubMed Abstract available

JUTKOWITZ E, Pizzi LT, Shewmaker P, Alarid-Escudero F, et al
Cost effectiveness of non-drug interventions that reduce nursing home admissions for people living with dementia.
Alzheimers Dement. 2023;19:3867-3893.
PubMed Abstract available

SINGH NA, Martin PR, Graff-Radford J, Machulda MM, et al
APOE epsilon4 influences within and between network functional connectivity in posterior cortical atrophy and logopenic progressive aphasia.
Alzheimers Dement. 2023;19:3858-3866.
PubMed Abstract available

COCHRAN JN, Acosta-Uribe J, Esposito BT, Madrigal L, et al
Genetic associations with age at dementia onset in the PSEN1 E280A Colombian kindred.
Alzheimers Dement. 2023;19:3835-3847.
PubMed Abstract available

BELLAVER B, Puig-Pijoan A, Ferrari-Souza JP, Leffa DT, et al
Blood-brain barrier integrity impacts the use of plasma amyloid-beta as a proxy of brain amyloid-beta pathology.
Alzheimers Dement. 2023;19:3815-3825.
PubMed Abstract available

BAXTER LC, Limback-Stokin M, Patten KJ, Arreola AC, et al
Hippocampal connectivity and memory decline in cognitively intact APOE epsilon4 carriers.
Alzheimers Dement. 2023;19:3806-3814.
PubMed Abstract available

August 2023

WINCHESTER LM, Harshfield EL, Shi L, Badhwar A, et al
Artificial intelligence for biomarker discovery in Alzheimer's disease and dementia.
Alzheimers Dement. 2023 Aug 31. doi: 10.1002/alz.13390.
PubMed Abstract available

BUSHNELL J, Hammers DB, Aisen P, Dage JL, et al
Influence of amyloid and diagnostic syndrome on non-traditional memory scores in early-onset Alzheimer's disease.
Alzheimers Dement. 2023 Aug 31. doi: 10.1002/alz.13434.
PubMed Abstract available

HARTLEY SL, Handen B, Tudorascu D, Lee L, et al
AT(N) biomarker profiles and Alzheimer's disease symptomology in Down syndrome.
Alzheimers Dement. 2023 Aug 28. doi: 10.1002/alz.13446.
PubMed Abstract available

GILLESPIE NA, Elman JA, McKenzie RE, Tu XM, et al
The heritability of blood-based biomarkers related to risk of Alzheimer's disease in a population-based sample of early old-age men.
Alzheimers Dement. 2023 Aug 25. doi: 10.1002/alz.13407.
PubMed Abstract available

PULVER RL, Kronberg E, Medenblik LM, Kheyfets VO, et al
Mapping sleep's oscillatory events as a biomarker of Alzheimer's disease.
Alzheimers Dement. 2023 Aug 23. doi: 10.1002/alz.13420.
PubMed Abstract available

ECHEVARRIA-COOPER SL, Ho EH, Gershon RC, Weintraub S, et al
Evaluation of the NIH Toolbox Odor Identification Test across normal cognition, amnestic mild cognitive impairment, and dementia due to Alzheimer's disease.
Alzheimers Dement. 2023 Aug 21. doi: 10.1002/alz.13426.
PubMed Abstract available

MIRANDA A, Rubovits E, Mudar R, Leung V, et al
Where are caregivers in the clinical trial? Evaluation of caregiver responsibilities in Alzheimer's disease and related dementias clinical trials.
Alzheimers Dement. 2023 Aug 18. doi: 10.1002/alz.13418.
PubMed Abstract available

TEJEDA M, Farrell J, Zhu C, Wetzler L, et al
DNA from multiple viral species is associated with Alzheimer's disease risk.
Alzheimers Dement. 2023 Aug 14. doi: 10.1002/alz.13414.
PubMed Abstract available

STRAIN JF, Phuah CL, Adeyemo B, Cheng K, et al
White matter hyperintensity longitudinal morphometric analysis in association with Alzheimer disease.
Alzheimers Dement. 2023 Aug 10. doi: 10.1002/alz.13377.
PubMed Abstract available

PYUN JM, Park YH, Wang J, Bennett DA, et al
Transcriptional risk scores in Alzheimer's disease: From pathology to cognition.
Alzheimers Dement. 2023 Aug 10. doi: 10.1002/alz.13406.
PubMed Abstract available

TIAN Q, Bilgel M, Walker KA, Moghekar AR, et al
Skeletal muscle mitochondrial function predicts cognitive impairment and is associated with biomarkers of Alzheimer's disease and neurodegeneration.
Alzheimers Dement. 2023 Aug 2. doi: 10.1002/alz.13388.
PubMed Abstract available

PILOTTO A, Bongianni M, Tirloni C, Galli A, et al
CSF alpha-synuclein aggregates by seed amplification and clinical presentation of AD.
Alzheimers Dement. 2023;19:3754-3759.
PubMed Abstract available

KOPEC RE, Chasman DI, Okereke OI, Sesso HD, et al
Re-remembering the influence of randomized beta-carotene on cognitive decline.
Alzheimers Dement. 2023;19:3718-3721.
PubMed Abstract available

LOIZOS M, Zhu CW, Akrivos J, Sewell M, et al
Evaluating memory testing to distinguish dementia severity among White, Black, and Spanish-speaking individuals in the Uniform Data Set (UDS).
Alzheimers Dement. 2023;19:3625-3634.
PubMed Abstract available

ESTEPP TG, Charnigo RJ, Abner EL, Jicha GA, et al
Associations of potential ADRD plasma biomarkers in cognitively normal volunteers.
Alzheimers Dement. 2023;19:3593-3601.
PubMed Abstract available

BABULAL GM, Zhu Y, Trani JF
Racial and ethnic differences in neuropsychiatric symptoms and progression to incident cognitive impairment among community-dwelling participants.
Alzheimers Dement. 2023;19:3635-3643.
PubMed Abstract available

WOLZAK K, Vermunt L, Campo MD, Jorge-Oliva M, et al
Protein disulfide isomerases as CSF biomarkers for the neuronal response to tau pathology.
Alzheimers Dement. 2023;19:3563-3574.
PubMed Abstract available

NISENBAUM L, Martone R, Chen T, Rajagovindan R, et al
CSF biomarker concordance with amyloid PET in Phase 3 studies of aducanumab.
Alzheimers Dement. 2023;19:3379-3388.
PubMed Abstract available

SNYDER A, Grant H, Chou A, Lindbergh CA, et al
Immune cell counts in cerebrospinal fluid predict cognitive function in aging and neurodegenerative disease.
Alzheimers Dement. 2023;19:3339-3349.
PubMed Abstract available

July 2023

WANG ZB, Tan L, Gao PY, Ma YH, et al
Associations of the A/T/N profiles in PET, CSF, and plasma biomarkers with Alzheimer's disease neuropathology at autopsy.
Alzheimers Dement. 2023 Jul 28. doi: 10.1002/alz.13413.
PubMed Abstract available

VAN DER SCHAAR J, Visser LNC, Ket JCF, Groot C, et al
Impact of sharing Alzheimer's disease biomarkers with individuals without dementia: A systematic review and meta-analysis of empirical data.
Alzheimers Dement. 2023 Jul 26. doi: 10.1002/alz.13410.
PubMed Abstract available

NEMES S, Logan PE, Manchella MK, Mundada NS, et al
Sex and APOE epsilon4 carrier effects on atrophy, amyloid PET, and tau PET burden in early-onset Alzheimer's disease.
Alzheimers Dement. 2023 Jul 26. doi: 10.1002/alz.13403.
PubMed Abstract available

LIAO Y, Wang Y, Tao QQ, Yang C, et al
CALHM2 V136G polymorphism reduces astrocytic ATP release and is associated with depressive symptoms and Alzheimer's disease risk.
Alzheimers Dement. 2023 Jul 26. doi: 10.1002/alz.13366.
PubMed Abstract available

BROOKE B, Lidan Z, Scherazad K, Jane AK, et al
Sex and gender differences in risk scores for dementia and Alzheimer's disease among cisgender, transgender, and non-binary adults.
Alzheimers Dement. 2023 Jul 26. doi: 10.1002/alz.13317.
PubMed Abstract available

DAGE JL, Eloyan A, Thangarajah M, Hammers DB, et al
Cerebrospinal fluid biomarkers in the Longitudinal Early-onset Alzheimer's Disease Study.
Alzheimers Dement. 2023 Jul 25. doi: 10.1002/alz.13399.
PubMed Abstract available

ELOYAN A, Thangarajah M, An N, Borowski BJ, et al
White matter hyperintensities are higher among early-onset Alzheimer's disease participants than their cognitively normal and early-onset nonAD peers: Longitudinal Early-onset Alzheimer's Disease Study (LEADS).
Alzheimers Dement. 2023 Jul 25. doi: 10.1002/alz.13402.
PubMed Abstract available

SINTINI I, Graff-Radford J, Schwarz CG, Machulda MM, et al
Longitudinal rates of atrophy and tau accumulation differ between the visual and language variants of atypical Alzheimer's disease.
Alzheimers Dement. 2023 Jul 23. doi: 10.1002/alz.13396.
PubMed Abstract available

YU SP, Jiang M, Berglund K, Wei L, et al
Strain hypothesis and additional evidence of the GluN3A deficiency-mediated pathogenesis of Alzheimer's disease.
Alzheimers Dement. 2023 Jul 23. doi: 10.1002/alz.13374.
PubMed Abstract available

GOLLAN TH, Garcia DL, Stasenko A, Murillo M, et al
The MINT Sprint 2.0: A picture naming test for detection of naming impairments in Alzheimer's disease and in preclinical AD.
Alzheimers Dement. 2023 Jul 19. doi: 10.1002/alz.13381.
PubMed Abstract available

DAS S, Li Z, Wachter A, Alla S, et al
Distinct transcriptomic responses to Abeta plaques, neurofibrillary tangles, and APOE in Alzheimer's disease.
Alzheimers Dement. 2023 Jul 17. doi: 10.1002/alz.13387.
PubMed Abstract available

DHANA K, Beck T, Desai P, Wilson RS, et al
Prevalence of Alzheimer's disease dementia in the 50 US states and 3142 counties: A population estimate using the 2020 bridged-race postcensal from the National Center for Health Statistics.
Alzheimers Dement. 2023 Jul 17. doi: 10.1002/alz.13081.
PubMed Abstract available

RAHMAN-FILIPIAK A, Bolton C, Grill JD, Rostamzadeh A, et al
Biomarker disclosure protocols in prodromal Alzheimer's disease clinical trials.
Alzheimers Dement. 2023 Jul 14. doi: 10.1002/alz.13380.
PubMed Abstract available

SLEIMAN PM, Qu HQ, Connolly JJ, Mentch F, et al
Trans-ethnic genomic informed risk assessment for Alzheimer's disease: An International Hundred K+ Cohorts Consortium study.
Alzheimers Dement. 2023 Jul 14. doi: 10.1002/alz.13378.
PubMed Abstract available

GARNIER-CRUSSARD A, Chetelat G
White matter hyperintensities in Alzheimer's disease: Beyond (but not instead of) the vascular contribution.
Alzheimers Dement. 2023 Jul 12. doi: 10.1002/alz.13372.
PubMed

BRICKMAN AM, Rizvi B
White matter hyperintensities and Alzheimer's disease: An alternative view of an alternative hypothesis.
Alzheimers Dement. 2023 Jul 12. doi: 10.1002/alz.13371.
PubMed

KRISHNAMURTHY S, Rollin FG
We must be clear that the root cause of racial disparities in Alzheimer's disease is racism.
Alzheimers Dement. 2023 Jul 12. doi: 10.1002/alz.13389.
PubMed

VINZE S, Chodosh J, Lee M, Wright J, et al
The national public health response to Alzheimer's disease and related dementias: Origins, evolution, and recommendations to improve early detection.
Alzheimers Dement. 2023 Jul 12. doi: 10.1002/alz.13376.
PubMed Abstract available

CHOUDHURY P, Zhang N, Adler CH, Chen K, et al
Longitudinal motor decline in dementia with Lewy bodies, Parkinson disease dementia, and Alzheimer's dementia in a community autopsy cohort.
Alzheimers Dement. 2023 Jul 8. doi: 10.1002/alz.13357.
PubMed Abstract available

BAE J, Logan PE, Acri DJ, Bharthur A, et al
A simulative deep learning model of SNP interactions on chromosome 19 for predicting Alzheimer's disease risk and rates of disease progression.
Alzheimers Dement. 2023 Jul 6. doi: 10.1002/alz.13319.
PubMed Abstract available

WANG K, Tang W, Hao X, Zhao J, et al
Ultra-processed food consumption and risk of dementia and Alzheimer's disease: Long-term results from the Framingham Offspring Study.
Alzheimers Dement. 2023 Jul 3. doi: 10.1002/alz.13351.
PubMed Abstract available

DONAGHY PC, Carrarini C, Ferreira D, Habich A, et al
Research diagnostic criteria for mild cognitive impairment with Lewy bodies: A systematic review and meta-analysis.
Alzheimers Dement. 2023;19:3186-3202.
PubMed Abstract available

WALKER JM, Goette W, Farrell K, Iida MA, et al
The relationship between hippocampal amyloid beta burden and spatial distribution of neurofibrillary degeneration.
Alzheimers Dement. 2023;19:3158-3170.
PubMed Abstract available

VASILJEVIC E, Koscik RL, Jonaitis E, Betthauser T, et al
Cognitive trajectories diverge by genetic risk in a preclinical longitudinal cohort.
Alzheimers Dement. 2023;19:3108-3118.
PubMed Abstract available

ORTEGA-CRUZ D, Uceda-Heras A, Iglesias JE, Zea-Sevilla MA, et al
A novel histological staging of hippocampal sclerosis that is evident in gray matter loss in vivo.
Alzheimers Dement. 2023;19:3028-3040.
PubMed Abstract available

LAUKKA EJ, Ekstrom I, Larsson M, Grande G, et al
Markers of olfactory dysfunction and progression to dementia: A 12-year population-based study.
Alzheimers Dement. 2023;19:3019-3027.
PubMed Abstract available

PHONGPREECHA T, Cholerton B, Bukhari S, Chang AL, et al
Prediction of neuropathologic lesions from clinical data.
Alzheimers Dement. 2023;19:3005-3018.
PubMed Abstract available

LEUZY A, Mattsson-Carlgren N, Cullen NC, Stomrud E, et al
Robustness of CSF Abeta42/40 and Abeta42/P-tau181 measured using fully automated immunoassays to detect AD-related outcomes.
Alzheimers Dement. 2023;19:2994-3004.
PubMed Abstract available

SALVADO G, Larsson V, Cody KA, Cullen NC, et al
Optimal combinations of CSF biomarkers for predicting cognitive decline and clinical conversion in cognitively unimpaired participants and mild cognitive impairment patients: A multi-cohort study.
Alzheimers Dement. 2023;19:2943-2955.
PubMed Abstract available

PILLAI JA, Bena J, Maly EF, Leverenz JB, et al
Initial non-amnestic symptoms relate to faster rate of functional and cognitive decline compared to amnestic symptoms in neuropathologically confirmed dementias.
Alzheimers Dement. 2023;19:2956-2965.
PubMed Abstract available

DUBBELMAN MA, Sikkes SAM, Ebenau JL, van Leeuwenstijn MSSA, et al
Changes in self- and study partner-perceived cognitive functioning in relation to amyloid status and future clinical progression: Findings from the SCIENCe project.
Alzheimers Dement. 2023;19:2933-2942.
PubMed Abstract available

PERNA L, Mons U, Stocker H, Beyer L, et al
High cholesterol levels change the association of biomarkers of neurodegenerative diseases with dementia risk: Findings from a population-based cohort.
Alzheimers Dement. 2023;19:2913-2922.
PubMed Abstract available

RAJBANSHI B, Guruacharya A, Mandell JW, Bloom GS, et al
Localization, induction, and cellular effects of tau phosphorylated at threonine 217.
Alzheimers Dement. 2023;19:2874-2887.
PubMed Abstract available

ZHANG M, Ganz AB, Rohde S, Rozemuller AJM, et al
Resilience and resistance to the accumulation of amyloid plaques and neurofibrillary tangles in centenarians: An age-continuous perspective.
Alzheimers Dement. 2023;19:2831-2841.
PubMed Abstract available

GOMEZ-TORTOSA E, Baradaran-Heravi Y, Dillen L, Choudhury NR, et al
TRIM25 mutation (p.C168*), coding for an E3 ubiquitin ligase, is a cause of early-onset autosomal dominant dementia with amyloid load and parkinsonism.
Alzheimers Dement. 2023;19:2805-2815.
PubMed Abstract available

WANG S, Wang J, Dove A, Guo J, et al
Association of impaired kidney function with dementia and brain pathologies: A community-based cohort study.
Alzheimers Dement. 2023;19:2765-2773.
PubMed Abstract available

June 2023

RAY NR, Ayodele T, Jean-Francois M, Baez P, et al
The Early-Onset Alzheimer's Disease Whole-Genome Sequencing Project: Study design and methodology.
Alzheimers Dement. 2023 Jun 30. doi: 10.1002/alz.13370.
PubMed Abstract available

GRIFFIN P, Apostolova L, Dickerson BC, Rabinovici G, et al
Developments in understanding early onset Alzheimer's disease.
Alzheimers Dement. 2023 Jun 30. doi: 10.1002/alz.13353.
PubMed Abstract available

MARQUINE MJ, Parks A, Perales-Puchalt J, Gonzalez DA, et al
Demographically-adjusted normative data among Latinos for the version 3 of the Alzheimer's Disease Centers' Neuropsychological Test Battery in the Uniform Data Set.
Alzheimers Dement. 2023 Jun 25. doi: 10.1002/alz.13313.
PubMed Abstract available

BOLLACK A, Pemberton HG, Collij LE, Markiewicz P, et al
Longitudinal amyloid and tau PET imaging in Alzheimer's disease: A systematic review of methodologies and factors affecting quantification.
Alzheimers Dement. 2023 Jun 12. doi: 10.1002/alz.13158.
PubMed Abstract available

YAKOUB Y, Ashton NJ, Strikwerda-Brown C, Montoliu-Gaya L, et al
Longitudinal blood biomarker trajectories in preclinical Alzheimer's disease.
Alzheimers Dement. 2023 Jun 9. doi: 10.1002/alz.13318.
PubMed Abstract available

POLSINELLI AJ, Wonderlin RJ, Hammers DB, Garcia AP, et al
Baseline neuropsychiatric symptoms and psychotropic medication use midway through data collection of the Longitudinal Early-Onset Alzheimer's Disease Study (LEADS) cohort.
Alzheimers Dement. 2023 Jun 9. doi: 10.1002/alz.13344.
PubMed Abstract available

LATHE R, Schultek NM, Balin BJ, Ehrlich GD, et al
Establishment of a consensus protocol to explore the brain pathobiome in patients with mild cognitive impairment and Alzheimer's disease: Research outline and call for collaboration: Research outline and call for collaboration.
Alzheimers Dement. 2023 Jun 7. doi: 10.1002/alz.13076.
PubMed Abstract available

VILA-CASTELAR C, Chen Y, Langella S, Lopera F, et al
Sex differences in blood biomarkers and cognitive performance in individuals with autosomal dominant Alzheimer's disease.
Alzheimers Dement. 2023 Jun 6. doi: 10.1002/alz.13314.
PubMed Abstract available

MATTKE S, Loh WK, Yuen KH, Yoong J, et al
Preparedness of China's health care system to provide access to a disease-modifying Alzheimer's treatment.
Alzheimers Dement. 2023 Jun 6. doi: 10.1002/alz.13348.
PubMed Abstract available

KNAPSKOG AB, Aksnes M, Edwin TH, Ueland PM, et al
Higher concentrations of kynurenic acid in CSF are associated with the slower clinical progression of Alzheimer's disease.
Alzheimers Dement. 2023 Jun 2. doi: 10.1002/alz.13162.
PubMed Abstract available

KRONIMUS Y, Albus A, Hasenberg M, Walkenfort B, et al
Fc N-glycosylation of autoreactive Abeta antibodies as a blood-based biomarker for Alzheimer's disease.
Alzheimers Dement. 2023 Jun 1. doi: 10.1002/alz.13124.
PubMed Abstract available

LI D, Farrell JJ, Mez J, Martin ER, et al
Novel loci for Alzheimer's disease identified by a genome-wide association study in Ashkenazi Jews.
Alzheimers Dement. 2023 Jun 1. doi: 10.1002/alz.13117.
PubMed Abstract available

COLEMAN ME, Roessler MEH, Peng S, Roth AR, et al
Social enrichment on the job: Complex work with people improves episodic memory, promotes brain reserve, and reduces the risk of dementia.
Alzheimers Dement. 2023;19:2655-2665.
PubMed Abstract available

KLOSKE CM, Barnum CJ, Batista AF, Bradshaw EM, et al
APOE and immunity: Research highlights.
Alzheimers Dement. 2023;19:2677-2696.
PubMed Abstract available

THANAPORNSANGSUTH P, Booncharoen K, Luechaipanit W, Supharatpariyakorn T, et al
Prospective evaluation of plasma phosphorylated tau in a real-life memory clinic in Thailand.
Alzheimers Dement. 2023;19:2745-2749.
PubMed Abstract available

HRAST B, Khachatryan E, Suput D, Van Hulle MM, et al
Effects of risk factors on longitudinal changes in brain structure and function in the progression of AD.
Alzheimers Dement. 2023;19:2666-2676.
PubMed Abstract available

LEHMANN S, Schraen-Maschke S, Vidal JS, Allinquant B, et al
Plasma Abeta42/Abeta40 ratio is independent of renal function.
Alzheimers Dement. 2023;19:2737-2739.
PubMed

PETERSEN RC, Aisen PS, Andrews JS, Atri A, et al
Expectations and clinical meaningfulness of randomized controlled trials.
Alzheimers Dement. 2023;19:2730-2736.
PubMed Abstract available

KING D, Holt K, Toombs J, He X, et al
Synaptic resilience is associated with maintained cognition during ageing.
Alzheimers Dement. 2023;19:2560-2574.
PubMed Abstract available

THORWALD MA, Silva J, Head E, Finch CE, et al
Amyloid futures in the expanding pathology of brain aging and dementia.
Alzheimers Dement. 2023;19:2605-2617.
PubMed Abstract available

SMITH R, Cullen NC, Pichet Binette A, Leuzy A, et al
Tau-PET is superior to phospho-tau when predicting cognitive decline in symptomatic AD patients.
Alzheimers Dement. 2023;19:2497-2507.
PubMed Abstract available

NICHOLS E, Brickman AM, Casaletto KB, Dams-O'Connor K, et al
AD and non-AD mediators of the pathway between the APOE genotype and cognition.
Alzheimers Dement. 2023;19:2508-2519.
PubMed Abstract available

ADHIKARI UK, Khan R, Mikhael M, Balez R, et al
Therapeutic anti-amyloid beta antibodies cause neuronal disturbances.
Alzheimers Dement. 2023;19:2479-2496.
PubMed Abstract available

LAN G, Li A, Liu Z, Ma S, et al
Presynaptic membrane protein dysfunction occurs prior to neurodegeneration and predicts faster cognitive decline.
Alzheimers Dement. 2023;19:2408-2419.
PubMed Abstract available

COLLIJ LE, Salvado G, de Wilde A, Altomare D, et al
Quantification of [(18) F]florbetaben amyloid-PET imaging in a mixed memory clinic population: The ABIDE project.
Alzheimers Dement. 2023;19:2397-2407.
PubMed Abstract available

LUSK JB, Ford C, Clark AG, Greiner MA, et al
Racial/ethnic disparities in dementia incidence, outcomes, and health-care utilization.
Alzheimers Dement. 2023;19:2376-2388.
PubMed Abstract available

GONCALVES RA, Sudo FK, Lourenco MV, Drummond C, et al
Cerebrospinal fluid irisin and lipoxin A4 are reduced in elderly Brazilian individuals with depression: Insight into shared mechanisms between depression and dementia.
Alzheimers Dement. 2023;19:2595-2604.
PubMed Abstract available

SADAGHIANI S, Trotman W, Lim SA, Chung E, et al
Associations of phosphorylated tau pathology with whole-hemisphere ex vivo morphometry in 7 tesla MRI.
Alzheimers Dement. 2023;19:2355-2364.
PubMed Abstract available

LESPINASSE J, Chene G, Mangin JF, Dubois B, et al
Associations among hypertension, dementia biomarkers, and cognition: The MEMENTO cohort.
Alzheimers Dement. 2023;19:2332-2342.
PubMed Abstract available

SUCHY-DICEY A, Su Y, Buchwald DS, Manson SM, et al
Volume atrophy in medial temporal cortex and verbal memory scores in American Indians: Data from the Strong Heart Study.
Alzheimers Dement. 2023;19:2298-2306.
PubMed Abstract available

May 2023

HAMMERS DB, Eloyan A, Taurone A, Thangarajah M, et al
Profiling baseline performance on the Longitudinal Early-Onset Alzheimer's Disease Study (LEADS) cohort near the midpoint of data collection.
Alzheimers Dement. 2023 May 31. doi: 10.1002/alz.13160.
PubMed Abstract available

LUTZ MW, Chiba-Falek O
Bioinformatics pipeline to guide post-GWAS studies in Alzheimer's: A new catalogue of disease candidate short structural variants.
Alzheimers Dement. 2023 May 30. doi: 10.1002/alz.13168.
PubMed Abstract available

HAMMERS DB, Nemes S, Diedrich T, Eloyan A, et al
Learning slopes in early-onset Alzheimer's disease.
Alzheimers Dement. 2023 May 27. doi: 10.1002/alz.13159.
PubMed Abstract available

HUBER H, Ashton NJ, Schieren A, Montoliu-Gaya L, et al
Levels of Alzheimer's disease blood biomarkers are altered after food intake-A pilot intervention study in healthy adults.
Alzheimers Dement. 2023 May 27. doi: 10.1002/alz.13163.
PubMed Abstract available

SAITO Y, Kamagata K, Uchida W, Takabayashi K, et al
The partial volume effect of choroid plexus in pathogenesis of Alzheimer's disease.
Alzheimers Dement. 2023 May 26. doi: 10.1002/alz.13123.
PubMed

STERN AM
Anti-dementia bias and Medicare regulation of Alzheimer's disease care.
Alzheimers Dement. 2023 May 24. doi: 10.1002/alz.13166.
PubMed

WIESE LAK, Gibson A, Guest MA, Nelson AR, et al
Global rural health disparities in Alzheimer's disease and related dementias: State of the science.
Alzheimers Dement. 2023 May 23. doi: 10.1002/alz.13104.
PubMed Abstract available

WANG J, Chen M, Masters CL, Wang YJ, et al
Translating blood biomarkers into clinical practice for Alzheimer's disease: Challenges and perspectives.
Alzheimers Dement. 2023 May 23. doi: 10.1002/alz.13116.
PubMed Abstract available

PANYARD DJ, McKetney J, Deming YK, Morrow AR, et al
Large-scale proteome and metabolome analysis of CSF implicates altered glucose and carbon metabolism and succinylcarnitine in Alzheimer's disease.
Alzheimers Dement. 2023 May 22. doi: 10.1002/alz.13130.
PubMed Abstract available

BILGEL M, An Y, Walker KA, Moghekar AR, et al
Longitudinal changes in Alzheimer's-related plasma biomarkers and brain amyloid.
Alzheimers Dement. 2023 May 22. doi: 10.1002/alz.13157.
PubMed Abstract available

BYFIELD G, Starks TD, Luther R, Edwards CL, et al
Leveraging African American family connectors for Alzheimer's disease genomic studies.
Alzheimers Dement. 2023 May 22. doi: 10.1002/alz.13106.
PubMed Abstract available

BODART-SANTOS V, Pinheiro LS, da Silva-Junior AJ, Froza RL, et al
Alzheimer's disease brain-derived extracellular vesicles reveal altered synapse-related proteome and induce cognitive impairment in mice.
Alzheimers Dement. 2023 May 19. doi: 10.1002/alz.13134.
PubMed Abstract available

PEROVNIK M, Tang CC, Namias M, Eidelberg D, et al
Longitudinal changes in metabolic network activity in early Alzheimer's disease.
Alzheimers Dement. 2023 May 19. doi: 10.1002/alz.13137.
PubMed Abstract available

LI M, Li Y, Schindler SE, Yen D, et al
Design and feasibility of an Alzheimer's disease blood test study in a diverse community-based population.
Alzheimers Dement. 2023 May 19. doi: 10.1002/alz.13125.
PubMed Abstract available

KARMARKAR AM, Roy I, Rivera-Hernandez M, Shaibi S, et al
Examining the role of race and quality of home health agencies in delayed initiation of home health services for individuals with Alzheimer's disease and related dementias (ADRD).
Alzheimers Dement. 2023 May 19. doi: 10.1002/alz.13139.
PubMed Abstract available

EVANS CD, Sparks J, Andersen SW, Brooks DA, et al
APOE epsilon4's impact on response to amyloid therapies in early symptomatic Alzheimer's disease: Analyses from multiple clinical trials.
Alzheimers Dement. 2023 May 19. doi: 10.1002/alz.13128.
PubMed Abstract available

LANGBAUM JB, Maloney E, Hennessy M, Harkins K, et al
How intention to join an Alzheimer's participant recruitment registry differs by race, ethnicity, sex, and family history: Results from a national survey of US adults.
Alzheimers Dement. 2023 May 19. doi: 10.1002/alz.13126.
PubMed Abstract available

TUMURBAATAR B, Fracassi A, Scaduto P, Guptarak J, et al
Preserved autophagy in cognitively intact non-demented individuals with Alzheimer's neuropathology.
Alzheimers Dement. 2023 May 16. doi: 10.1002/alz.13074.
PubMed Abstract available

CHUNG J, Sahelijo N, Maruyama T, Hu J, et al
Alzheimer's disease heterogeneity explained by polygenic risk scores derived from brain transcriptomic profiles.
Alzheimers Dement. 2023 May 11. doi: 10.1002/alz.13069.
PubMed Abstract available

SHULMAN D, Dubnov S, Zorbaz T, Madrer N, et al
Sex-specific declines in cholinergic-targeting tRNA fragments in the nucleus accumbens in Alzheimer's disease.
Alzheimers Dement. 2023 May 9. doi: 10.1002/alz.13095.
PubMed Abstract available

D'ALESSANDRO A, Lukens JR, Zimring JC
The role of PIMT in Alzheimer's disease pathogenesis: A novel hypothesis.
Alzheimers Dement. 2023 May 8. doi: 10.1002/alz.13115.
PubMed Abstract available

QUINNEY SK, Murugesh K, Oblak A, Onos KD, et al
STOP-AD portal: Selecting the optimal pharmaceutical for preclinical drug testing in Alzheimer's disease.
Alzheimers Dement. 2023 May 8. doi: 10.1002/alz.13108.
PubMed Abstract available

MILLER MR, Lee YF, Kastanenka KV
Calcium sensor Yellow Cameleon 3.6 as a tool to support the calcium hypothesis of Alzheimer's disease.
Alzheimers Dement. 2023 May 8. doi: 10.1002/alz.13111.
PubMed Abstract available

WEBBER EK, Fivaz M, Stutzmann GE, Griffioen G, et al
Cytosolic calcium: Judge, jury and executioner of neurodegeneration in Alzheimer's disease and beyond.
Alzheimers Dement. 2023 May 3. doi: 10.1002/alz.13065.
PubMed Abstract available

REAS ET, Shadrin A, Frei O, Motazedi E, et al
Improved multimodal prediction of progression from MCI to Alzheimer's disease combining genetics with quantitative brain MRI and cognitive measures.
Alzheimers Dement. 2023 May 2. doi: 10.1002/alz.13112.
PubMed Abstract available

VASUNILASHORN SM, Lunardi N, Newman JC, Crosby G, et al
Preclinical and translational models for delirium: Recommendations for future research from the NIDUS delirium network.
Alzheimers Dement. 2023;19:2150-2174.
PubMed Abstract available

DALY T
Amyloid PET-assisted diagnosis and improved outcomes: Biomarkering or biomarketing?
Alzheimers Dement. 2023;19:2211.
PubMed

POLSINELLI AJ, Lane KA, Manchella MK, Logan PE, et al
APOE epsilon4 is associated with earlier symptom onset in LOAD but later symptom onset in EOAD.
Alzheimers Dement. 2023;19:2212-2217.
PubMed Abstract available

WOLFF JL, DesRoches CM, Amjad H, Burgdorf JG, et al
Catalyzing dementia care through the learning health system and consumer health information technology.
Alzheimers Dement. 2023;19:2197-2207.
PubMed Abstract available

JONSDOTTIR MK, Harrison J, Hannesdottir KI
The ambivalence toward neuropsychology in dementia research, diagnosis, and drug development: Myths and misconceptions.
Alzheimers Dement. 2023;19:2175-2181.
PubMed Abstract available

KISBY GE, Oakes H, Beckett D, Spencer PS, et al
MGMT, a risk factor for both genetic and environmental forms of dementia.
Alzheimers Dement. 2023;19:2208-2210.
PubMed Abstract available

VAN MAURIK IS, Broulikova HM, Mank A, Bakker ED, et al
A more precise diagnosis by means of amyloid PET contributes to delayed institutionalization, lower mortality, and reduced care costs in a tertiary memory clinic setting.
Alzheimers Dement. 2023;19:2006-2013.
PubMed Abstract available

POLSTERL S, Wachinger C
Identification of causal effects of neuroanatomy on cognitive decline requires modeling unobserved confounders.
Alzheimers Dement. 2023;19:1994-2005.
PubMed Abstract available

ASHTON NJ, Puig-Pijoan A, Mila-Aloma M, Fernandez-Lebrero A, et al
Plasma and CSF biomarkers in a memory clinic: Head-to-head comparison of phosphorylated tau immunoassays.
Alzheimers Dement. 2023;19:1913-1924.
PubMed Abstract available

WORTHA SM, Frenzel S, Bahls M, Habes M, et al
Association of spermidine plasma levels with brain aging in a population-based study.
Alzheimers Dement. 2023;19:1832-1840.
PubMed Abstract available

SWADDIWUDHIPONG N, Whiteside DJ, Hezemans FH, Street D, et al
Pre-diagnostic cognitive and functional impairment in multiple sporadic neurodegenerative diseases.
Alzheimers Dement. 2023;19:1752-1763.
PubMed Abstract available

KLEINEIDAM L, Wagner M, Guski J, Wolfsgruber S, et al
Disentangling the relationship of subjective cognitive decline and depressive symptoms in the development of cognitive decline and dementia.
Alzheimers Dement. 2023;19:2056-2068.
PubMed Abstract available

April 2023

DINESH D, Shao Q, Palnati M, McDannold S, et al
The epidemiology of mild cognitive impairment, Alzheimer's disease and related dementia in U.S. veterans.
Alzheimers Dement. 2023 Apr 28. doi: 10.1002/alz.13071.
PubMed Abstract available

MGAIETH F, Baksh RA, Startin CM, Hamburg S, et al
Exploring semantic verbal fluency patterns and their relationship to age and Alzheimer's disease in adults with Down syndrome.
Alzheimers Dement. 2023 Apr 28. doi: 10.1002/alz.13097.
PubMed Abstract available

XIAO C, Pappas I, Aksman LM, O'Bryant SE, et al
Comparison of genetic and health risk factors for mild cognitive impairment and Alzheimer's disease between Hispanic and non-Hispanic white participants.
Alzheimers Dement. 2023 Apr 27. doi: 10.1002/alz.13110.
PubMed Abstract available

ADHIKARI S, Qiao Y, Singer M, Sagare A, et al
Retinotopic degeneration of the retina and optic tracts in autosomal dominant Alzheimer's disease.
Alzheimers Dement. 2023 Apr 27. doi: 10.1002/alz.13100.
PubMed Abstract available

OECKL P, Janelidze S, Halbgebauer S, Stomrud E, et al
Higher plasma beta-synuclein indicates early synaptic degeneration in Alzheimer's disease.
Alzheimers Dement. 2023 Apr 27. doi: 10.1002/alz.13103.
PubMed Abstract available

XU Y, Aung HL, Bateman RJ, Brooks WS, et al
Higher systolic blood pressure in early-mid adulthood is associated with poorer cognitive performance in those with a dominantly inherited Alzheimer's disease mutation but not in non-carriers. Results from the DIAN study.
Alzheimers Dement. 2023 Apr 23. doi: 10.1002/alz.13082.
PubMed Abstract available

IMBIMBO BP, Watling M, Imbimbo C, Nistico R, et al
Plasma ATN(I) classification and precision pharmacology in Alzheimer's disease.
Alzheimers Dement. 2023 Apr 20. doi: 10.1002/alz.13084.
PubMed Abstract available

THERRIAULT J, Servaes S, Tissot C, Rahmouni N, et al
Equivalence of plasma p-tau217 with cerebrospinal fluid in the diagnosis of Alzheimer's disease.
Alzheimers Dement. 2023 Apr 20. doi: 10.1002/alz.13026.
PubMed Abstract available

ADKINS-JACKSON PB, George KM, Besser LM, Hyun J, et al
The structural and social determinants of Alzheimer's disease related dementias.
Alzheimers Dement. 2023 Apr 19. doi: 10.1002/alz.13027.
PubMed Abstract available

KUMAR A, Su Y, Sharma M, Singh S, et al
MicroRNA expression in extracellular vesicles as a novel blood-based biomarker for Alzheimer's disease.
Alzheimers Dement. 2023 Apr 18. doi: 10.1002/alz.13055.
PubMed Abstract available

SASNER M, Territo PR, Sukoff Rizzo SJ
Meeting report of the annual workshop on Principles and Techniques for Improving Preclinical to Clinical Translation in Alzheimer's Disease research.
Alzheimers Dement. 2023 Apr 18. doi: 10.1002/alz.13093.
PubMed Abstract available

SAMUELS JD, Moore KA, Ennerfelt HE, Johnson AM, et al
The Alzheimer's disease risk factor INPP5D restricts neuroprotective microglial responses in amyloid beta-mediated pathology.
Alzheimers Dement. 2023 Apr 15. doi: 10.1002/alz.13089.
PubMed Abstract available

MORENO M, Kline CR, Lanigan K, Kallmyer B, et al
Personal meaningfulness of potential FDA-approved treatments: Perspectives of individuals living with Alzheimer's disease.
Alzheimers Dement. 2023 Apr 14. doi: 10.1002/alz.13079.
PubMed Abstract available

BAI H, Naj AC, Benchek P, Dumitrescu L, et al
A haptoglobin (HP) structural variant alters the effect of APOE alleles on Alzheimer's disease.
Alzheimers Dement. 2023 Apr 12. doi: 10.1002/alz.13050.
PubMed Abstract available

ZHOU RZ, Vetrano DL, Grande G, Duell F, et al
A glycan epitope correlates with tau in serum and predicts progression to Alzheimer's disease in combination with APOE4 allele status.
Alzheimers Dement. 2023 Apr 12. doi: 10.1002/alz.13024.
PubMed Abstract available

VIDELA L, Benejam B, Carmona-Iragui M, Barroeta I, et al
Cross-sectional versus longitudinal cognitive assessments for the diagnosis of symptomatic Alzheimer's disease in adults with Down syndrome.
Alzheimers Dement. 2023 Apr 11. doi: 10.1002/alz.13073.
PubMed Abstract available

CELIS K, Moreno MDMM, Rajabli F, Whitehead P, et al
Ancestry-related differences in chromatin accessibility and gene expression of APOE epsilon4 are associated with Alzheimer's disease risk.
Alzheimers Dement. 2023 Apr 10. doi: 10.1002/alz.13075.
PubMed Abstract available

HUANG CW, Rust NC, Wu HF, Yin A, et al
Low glucose induced Alzheimer's disease-like biochemical changes in human induced pluripotent stem cell-derived neurons is due to dysregulated O-GlcNAcylation.
Alzheimers Dement. 2023 Apr 10. doi: 10.1002/alz.13058.
PubMed Abstract available

GARNIER-CRUSSARD A, Cotton F, Krolak-Salmon P, Chetelat G, et al
White matter hyperintensities in Alzheimer's disease: Beyond vascular contribution.
Alzheimers Dement. 2023 Apr 7. doi: 10.1002/alz.13057.
PubMed Abstract available

CHATTERJEE M, Ozdemir S, Kunadt M, Koel-Simmelink M, et al
C1q is increased in cerebrospinal fluid-derived extracellular vesicles in Alzheimer's disease: A multi-cohort proteomics and immuno-assay validation study.
Alzheimers Dement. 2023 Apr 6. doi: 10.1002/alz.13066.
PubMed Abstract available

ROZALEM ARANHA M, Iulita MF, Montal V, Pegueroles J, et al
Basal forebrain atrophy along the Alzheimer's disease continuum in adults with Down syndrome.
Alzheimers Dement. 2023 Apr 6. doi: 10.1002/alz.12999.
PubMed Abstract available

DILMORE AH, Martino C, Neth BJ, West KA, et al
Effects of a ketogenic and low-fat diet on the human metabolome, microbiome, and foodome in adults at risk for Alzheimer's disease.
Alzheimers Dement. 2023 Apr 5. doi: 10.1002/alz.13007.
PubMed Abstract available

KUO K, Zhang YR, Chen SD, He XY, et al
Associations of grip strength, walking pace, and the risk of incident dementia: A prospective cohort study of 340212 participants.
Alzheimers Dement. 2023;19:1415-1427.
PubMed Abstract available

GIBSON LL, Grinberg LT, Ffytche D, Leite REP, et al
Neuropathological correlates of neuropsychiatric symptoms in dementia.
Alzheimers Dement. 2023;19:1372-1382.
PubMed Abstract available

RABE C, Bittner T, Jethwa A, Suridjan I, et al
Clinical performance and robustness evaluation of plasma amyloid-beta(42/40) prescreening.
Alzheimers Dement. 2023;19:1393-1402.
PubMed Abstract available

OECKL P, Anderl-Straub S, Danek A, Diehl-Schmid J, et al
Relationship of serum beta-synuclein with blood biomarkers and brain atrophy.
Alzheimers Dement. 2023;19:1358-1371.
PubMed Abstract available

OTTOY J, Ozzoude M, Zukotynski K, Adamo S, et al
Vascular burden and cognition: Mediating roles of neurodegeneration and amyloid PET.
Alzheimers Dement. 2023;19:1503-1517.
PubMed Abstract available

PANG M, Zhu L, Gabelle A, Gafson AR, et al
Effect of reduction in brain amyloid levels on change in cognitive and functional decline in randomized clinical trials: An instrumental variable meta-analysis.
Alzheimers Dement. 2023;19:1292-1299.
PubMed Abstract available

GROTHE MJ, Moscoso A, Silva-Rodriguez J, Lange C, et al
Differential diagnosis of amnestic dementia patients based on an FDG-PET signature of autopsy-confirmed LATE-NC.
Alzheimers Dement. 2023;19:1234-1244.
PubMed Abstract available

PALMA-GUDIEL H, Yu L, Huo Z, Yang J, et al
Fine-mapping and replication of EWAS loci harboring putative epigenetic alterations associated with AD neuropathology in a large collection of human brain tissue samples.
Alzheimers Dement. 2023;19:1216-1226.
PubMed Abstract available

PACYNA RR, Han SD, Wroblewski KE, McClintock MK, et al
Rapid olfactory decline during aging predicts dementia and GMV loss in AD brain regions.
Alzheimers Dement. 2023;19:1479-1490.
PubMed Abstract available

March 2023

CHEN XL, Fortes JM, Hu YT, van Iersel J, et al
Sexually dimorphic age-related molecular differences in the entorhinal cortex of cognitively intact elderly: Relation to early Alzheimer's changes.
Alzheimers Dement. 2023 Mar 24. doi: 10.1002/alz.13037.
PubMed Abstract available

WEINER S, Sauer M, Brinkmalm G, Constantinescu J, et al
SCRN1: A cerebrospinal fluid biomarker correlating with tau in Alzheimer's disease.
Alzheimers Dement. 2023 Mar 22. doi: 10.1002/alz.13042.
PubMed Abstract available

HOLDRIDGE KC, Yaari R, Hoban DB, Andersen S, et al
Targeting amyloid beta in Alzheimer's disease: Meta-analysis of low-dose solanezumab in Alzheimer's disease with mild dementia studies.
Alzheimers Dement. 2023 Mar 22. doi: 10.1002/alz.13031.
PubMed Abstract available

CHENG Y, Zamrini E, Faselis C, Redd D, et al
Cardiorespiratory fitness and risk of Alzheimer's disease and related dementias among American veterans.
Alzheimers Dement. 2023 Mar 22. doi: 10.1002/alz.12998.
PubMed Abstract available

CHAPPELLE SD, Gigliotti C, Leger GC, Peavy GM, et al
Comparison of the telephone-Montreal Cognitive Assessment (T-MoCA) and Telephone Interview for Cognitive Status (TICS) as screening tests for early Alzheimer's disease.
Alzheimers Dement. 2023 Mar 20. doi: 10.1002/alz.13039.
PubMed Abstract available

KUSTERS CDJ, Paul KC, Romero T, Sinsheimer JS, et al
Among men, androgens are associated with a decrease in Alzheimer's disease risk.
Alzheimers Dement. 2023 Mar 20. doi: 10.1002/alz.13013.
PubMed Abstract available

URAS I, Karayel-Basar M, Sahin B, Baykal AT, et al
Detection of early proteomic alterations in 5xFAD Alzheimer's disease neonatal mouse model via MALDI-MSI.
Alzheimers Dement. 2023 Mar 18. doi: 10.1002/alz.13008.
PubMed Abstract available

WESTON PSJ, Coath W, Harris MJ, Malone IB, et al
Cortical tau is associated with microstructural imaging biomarkers of neurite density and dendritic complexity in Alzheimer's disease.
Alzheimers Dement. 2023 Mar 18. doi: 10.1002/alz.13011.
PubMed Abstract available

SCHUMACHER J, Ray NJ, Hamilton CA, Bergamino M, et al
Free water imaging of the cholinergic system in dementia with Lewy bodies and Alzheimer's disease.
Alzheimers Dement. 2023 Mar 15. doi: 10.1002/alz.13034.
PubMed Abstract available

2023 Alzheimer's disease facts and figures.
Alzheimers Dement. 2023 Mar 14. doi: 10.1002/alz.13016.
PubMed Abstract available

MOURTZI N, Charisis S, Tsapanou A, Ntanasi E, et al
Genetic propensity for cerebral amyloidosis and risk of mild cognitive impairment and Alzheimer's disease within a cognitive reserve framework.
Alzheimers Dement. 2023 Mar 9. doi: 10.1002/alz.12980.
PubMed Abstract available

FERREIRA PCL, Zhang Y, Snitz B, Chang CH, et al
Plasma biomarkers identify older adults at risk of Alzheimer's disease and related dementias in a real-world population-based cohort.
Alzheimers Dement. 2023 Mar 6. doi: 10.1002/alz.12986.
PubMed Abstract available

MEYERS EA, Sexton C, Snyder HM, Carrillo MC, et al
Impact of Alzheimer's association support and engagement in the AD/ADRD research community through the COVID-19 pandemic and beyond.
Alzheimers Dement. 2023 Mar 5. doi: 10.1002/alz.13015.
PubMed Abstract available

ACKLEY SF, Glymour MM
Comment on "Effect of reduction in brain amyloid levels on change in cognitive and functional decline in randomized clinical trials: An updated instrumental variable meta-analysis".
Alzheimers Dement. 2023;19:1099-1100.
PubMed

ZICHA S, Bateman RJ, Shaw LM, Zetterberg H, et al
Comparative analytical performance of multiple plasma Abeta42 and Abeta40 assays and their ability to predict positron emission tomography amyloid positivity.
Alzheimers Dement. 2023;19:956-966.
PubMed Abstract available

February 2023

LIN PJ, Levine A, Rucker J, Chambers JD, et al
Variation in Medicaid and commercial payer coverage of aducanumab for Alzheimer's disease.
Alzheimers Dement. 2023 Feb 28. doi: 10.1002/alz.12965.
PubMed Abstract available

LLIBRE-GUERRA JJ, Heavener A, Brucki SMD, Marante JPD, et al
A call for clinical trial globalization in Alzheimer's disease and related dementia.
Alzheimers Dement. 2023 Feb 25. doi: 10.1002/alz.12995.
PubMed Abstract available

WANG ZB, Tan L, Wang HF, Chen SD, et al
Differences between ante mortem Alzheimer's disease biomarkers in predicting neuropathology at autopsy.
Alzheimers Dement. 2023 Feb 25. doi: 10.1002/alz.12997.
PubMed Abstract available

ZHANG W, Wang HF, Kuo K, Wang L, et al
Contribution of Alzheimer's disease pathology to biological and clinical progression: A longitudinal study across two cohorts.
Alzheimers Dement. 2023 Feb 25. doi: 10.1002/alz.12992.
PubMed Abstract available

YU L, Wang T, Wilson RS, Guo W, et al
Predicting age at Alzheimer's dementia onset with the cognitive clock.
Alzheimers Dement. 2023 Feb 24. doi: 10.1002/alz.13004.
PubMed Abstract available

CARNA M, Onyango IG, Katina S, Holub D, et al
Pathogenesis of Alzheimer's disease: Involvement of the choroid plexus.
Alzheimers Dement. 2023 Feb 24. doi: 10.1002/alz.12970.
PubMed Abstract available

LI M, Larsen PA
Single-cell sequencing of entorhinal cortex reveals widespread disruption of neuropeptide networks in Alzheimer's disease.
Alzheimers Dement. 2023 Feb 24. doi: 10.1002/alz.12979.
PubMed Abstract available

LI Q, Yang X, Xu J, Guo Y, et al
Early prediction of Alzheimer's disease and related dementias using real-world electronic health records.
Alzheimers Dement. 2023 Feb 23. doi: 10.1002/alz.12967.
PubMed Abstract available

WANG E, Wang M, Guo L, Fullard JF, et al
Genome-wide methylomic regulation of multiscale gene networks in Alzheimer's disease.
Alzheimers Dement. 2023 Feb 22. doi: 10.1002/alz.12969.
PubMed Abstract available

CHARISIS S, Lin H, Ray R, Joehanes R, et al
Obesity impacts the expression of Alzheimer's disease-related genes: The Framingham Heart Study.
Alzheimers Dement. 2023 Feb 22. doi: 10.1002/alz.12954.
PubMed Abstract available

SALONER R, Paolillo EW, Wojta KJ, Fonseca C, et al
Sex-specific effects of SNAP-25 genotype on verbal memory and Alzheimer's disease biomarkers in clinically normal older adults.
Alzheimers Dement. 2023 Feb 18. doi: 10.1002/alz.12989.
PubMed Abstract available

PURI S, Hu J, Sun Z, Lin M, et al
Identification of circRNAs linked to Alzheimer's disease and related dementias.
Alzheimers Dement. 2023 Feb 16. doi: 10.1002/alz.12960.
PubMed Abstract available

DEMING Y, Vasiljevic E, Morrow A, Miao J, et al
Neuropathology-based APOE genetic risk score better quantifies Alzheimer's risk.
Alzheimers Dement. 2023 Feb 16. doi: 10.1002/alz.12990.
PubMed Abstract available

ULEMAN JF, Melis RJF, Ntanasi E, Scarmeas N, et al
Simulating the multicausality of Alzheimer's disease with system dynamics.
Alzheimers Dement. 2023 Feb 16. doi: 10.1002/alz.12923.
PubMed Abstract available

SHI L, Xu J, Green R, Wretlind A, et al
Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN-derived networks and highlights causal links in Alzheimer's disease.
Alzheimers Dement. 2023 Feb 15. doi: 10.1002/alz.12961.
PubMed Abstract available

ZOU X, Liao Y, Jiang C, Yuan Y, et al
Brain perfusion, cognition, and plasma Alzheimer's biomarkers in moyamoya disease.
Alzheimers Dement. 2023 Feb 10. doi: 10.1002/alz.12958.
PubMed Abstract available

SOLFRIZZI V, Scafato E, Custodero C, Piazzolla G, et al
Biopsychosocial frailty and mild cognitive impairment subtypes: Findings from the Italian project on the epidemiology of Alzheimer's disease (IPREA).
Alzheimers Dement. 2023 Feb 9. doi: 10.1002/alz.12944.
PubMed Abstract available

FALGAS N, Walsh CM, Yack L, Simon AJ, et al
Alzheimer's disease phenotypes show different sleep architecture.
Alzheimers Dement. 2023 Feb 7. doi: 10.1002/alz.12963.
PubMed Abstract available

PLANCHE V, Mansencal B, Manjon JV, Tourdias T, et al
Anatomical MRI staging of frontotemporal dementia variants: For the Frontotemporal Lobar Degeneration Neuroimaging Initiative and the National Alzheimer's Coordinating Center cohort: For the Frontotemporal Lobar Degeneration Neuroimaging Initiative an
Alzheimers Dement. 2023 Feb 7. doi: 10.1002/alz.12975.
PubMed Abstract available

ELLISON TS, Cappa SF, Garrett D, Georges J, et al
Outcome measures for Alzheimer's disease: A global inter-societal Delphi consensus.
Alzheimers Dement. 2023 Feb 7. doi: 10.1002/alz.12945.
PubMed Abstract available

LI YJ, Nuytemans K, La JO, Jiang R, et al
Identification of novel genes for age-at-onset of Alzheimer's disease by combining quantitative and survival trait analyses.
Alzheimers Dement. 2023 Feb 4. doi: 10.1002/alz.12927.
PubMed Abstract available

Apply now to the Alzheimer's Association Interdisciplinary Summer Research Institute.
Alzheimers Dement. 2023 Feb 1. doi: 10.1002/alz.12973.
PubMed

DEVANAND DP, Masurkar AV, Wisniewski T
Vigorous, regular physical exercise may slow disease progression in Alzheimer's disease.
Alzheimers Dement. 2023 Feb 1. doi: 10.1002/alz.12946.
PubMed Abstract available

DONG Y, Li Y, Liu K, Han X, et al
Anosmia, mild cognitive impairment, and biomarkers of brain aging in older adults.
Alzheimers Dement. 2023;19:589-601.
PubMed Abstract available

LLIBRE-GUERRA JJ, Li J, Qian Y, Llibre-Rodriguez JJ, et al
Apolipoprotein E (APOE) genotype, dementia, and memory performance among Caribbean Hispanic versus US populations.
Alzheimers Dement. 2023;19:602-610.
PubMed Abstract available

RAMOS J, Caywood LJ, Prough MB, Clouse JE, et al
Genetic variants in the SHISA6 gene are associated with delayed cognitive impairment in two family datasets.
Alzheimers Dement. 2023;19:611-620.
PubMed Abstract available

WEIJS RWJ, Shkredova DA, Brekelmans ACM, Thijssen DHJ, et al
Longitudinal changes in cerebral blood flow and their relation with cognitive decline in patients with dementia: Current knowledge and future directions.
Alzheimers Dement. 2023;19:532-548.
PubMed Abstract available

SEMMENS EO, Leary CS, Fitzpatrick AL, Ilango SD, et al
Air pollution and dementia in older adults in the Ginkgo Evaluation of Memory Study.
Alzheimers Dement. 2023;19:549-559.
PubMed Abstract available

LANDAU SM, Ward TJ, Murphy A, Iaccarino L, et al
Quantification of amyloid beta and tau PET without a structural MRI.
Alzheimers Dement. 2023;19:444-455.
PubMed Abstract available

WANG L, Davis PB, Kaelber DC, Xu R, et al
COVID-19 breakthrough infections and hospitalizations among vaccinated patients with dementia in the United States between December 2020 and August 2021.
Alzheimers Dement. 2023;19:421-432.
PubMed Abstract available

January 2023

WANG X, Broce I, Qiu Y, Deters KD, et al
A simple genetic stratification method for lower cost, more expedient clinical trials in early Alzheimer's disease: A preliminary study of tau PET and cognitive outcomes.
Alzheimers Dement. 2023 Jan 26. doi: 10.1002/alz.12952.
PubMed Abstract available

GRAHAM NSN, Cole JH, Bourke NJ, Schott JM, et al
Distinct patterns of neurodegeneration after TBI and in Alzheimer's disease.
Alzheimers Dement. 2023 Jan 25. doi: 10.1002/alz.12934.
PubMed Abstract available

LIU H, Barthelemy NR, Ovod V, Bollinger JG, et al
Acute sleep loss decreases CSF-to-blood clearance of Alzheimer's disease biomarkers.
Alzheimers Dement. 2023 Jan 25. doi: 10.1002/alz.12930.
PubMed Abstract available

ZAWAR I, Kapur J
Does Alzheimer's disease with mesial temporal lobe epilepsy represent a distinct disease subtype?
Alzheimers Dement. 2023 Jan 17. doi: 10.1002/alz.12943.
PubMed Abstract available

EHRENBERG AJ, Kelberman MA, Liu KY, Dahl MJ, et al
Priorities for research on neuromodulatory subcortical systems in Alzheimer's disease: Position paper from the NSS PIA of ISTAART.
Alzheimers Dement. 2023 Jan 15. doi: 10.1002/alz.12937.
PubMed Abstract available

XIONG C, McCue LM, Buckles V, Grant E, et al
Cross-sectional and longitudinal comparisons of biomarkers and cognition among asymptomatic middle-aged individuals with a parental history of either autosomal dominant or late-onset Alzheimer's disease.
Alzheimers Dement. 2023 Jan 14. doi: 10.1002/alz.12912.
PubMed Abstract available

KRUSE C, Maier F, Spottke A, Bach JP, et al
Apathy in patients with Alzheimer's disease is a cost-driving factor.
Alzheimers Dement. 2023 Jan 2. doi: 10.1002/alz.12915.
PubMed Abstract available

TOLEDO JB, Abdelnour C, Weil RS, Ferreira D, et al
Dementia with Lewy bodies: Impact of co-pathologies and implications for clinical trial design.
Alzheimers Dement. 2023;19:318-332.
PubMed Abstract available

ROSEBOROUGH AD, Saad L, Goodman M, Cipriano LE, et al
White matter hyperintensities and longitudinal cognitive decline in cognitively normal populations and across diagnostic categories: A meta-analysis, systematic review, and recommendations for future study harmonization.
Alzheimers Dement. 2023;19:194-207.
PubMed Abstract available

December 2022

DAUAR MT, Labonte A, Picard C, Miron J, et al
Characterization of the contactin 5 protein and its risk-associated polymorphic variant throughout the Alzheimer's disease spectrum.
Alzheimers Dement. 2022 Dec 30. doi: 10.1002/alz.12868.
PubMed Abstract available

VELIOGLU HA, Ayyildiz B, Ayyildiz S, Sutcubasi B, et al
A structural and resting-state functional connectivity investigation of the pulvinar in elderly individuals and Alzheimer's disease patients.
Alzheimers Dement. 2022 Dec 28. doi: 10.1002/alz.12850.
PubMed Abstract available

CHATTERJEE P, Vermunt L, Gordon BA, Pedrini S, et al
Plasma glial fibrillary acidic protein in autosomal dominant Alzheimer's disease: Associations with Abeta-PET, neurodegeneration, and cognition.
Alzheimers Dement. 2022 Dec 28. doi: 10.1002/alz.12879.
PubMed Abstract available

AGUILLON D, Langella S, Chen Y, Sanchez JS, et al
Plasma p-tau217 predicts in vivo brain pathology and cognition in autosomal dominant Alzheimer's disease.
Alzheimers Dement. 2022 Dec 26. doi: 10.1002/alz.12906.
PubMed Abstract available

STRICKER NH, Twohy EL, Albertson SM, Karstens AJ, et al
Mayo-PACC: A parsimonious preclinical Alzheimer's disease cognitive composite comprised of public-domain measures to facilitate clinical translation.
Alzheimers Dement. 2022 Dec 24. doi: 10.1002/alz.12895.
PubMed Abstract available

LOGUE MW, Miller MW, Sherva R, Zhang R, et al
Alzheimer's disease and related dementias among aging veterans: Examining gene-by-environment interactions with post-traumatic stress disorder and traumatic brain injury.
Alzheimers Dement. 2022 Dec 22. doi: 10.1002/alz.12870.
PubMed Abstract available

HUSEBY CJ, Delvaux E, Brokaw DL, Coleman PD, et al
Blood RNA transcripts reveal similar and differential alterations in fundamental cellular processes in Alzheimer's disease and other neurodegenerative diseases.
Alzheimers Dement. 2022 Dec 21. doi: 10.1002/alz.12880.
PubMed Abstract available

RAJABLI F, Tosto G, Hamilton-Nelson KL, Kunkle BW, et al
Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans.
Alzheimers Dement. 2022 Dec 20. doi: 10.1002/alz.12865.
PubMed Abstract available

LIN PB, Tsai AP, Soni D, Lee-Gosselin A, et al
INPP5D deficiency attenuates amyloid pathology in a mouse model of Alzheimer's disease.
Alzheimers Dement. 2022 Dec 16. doi: 10.1002/alz.12849.
PubMed Abstract available

Alzheimer's Association names Dr. Joanne Pike its next chief executive officer.
Alzheimers Dement. 2022 Dec 9. doi: 10.1002/alz.12911.
PubMed

YASSINE HN, Self W, Kerman BE, Santoni G, et al
Nutritional metabolism and cerebral bioenergetics in Alzheimer's disease and related dementias.
Alzheimers Dement. 2022 Dec 8. doi: 10.1002/alz.12845.
PubMed Abstract available

BALL DE, Mattke S, Frank L, Murray JF, et al
A framework for addressing Alzheimer's disease: Without a frame, the work has no aim.
Alzheimers Dement. 2022 Dec 8. doi: 10.1002/alz.12869.
PubMed Abstract available

YU H, Wang M, Yang Q, Xu X, et al
The electrophysiological and neuropathological profiles of cerebellum in APP(swe) /PS1(DeltaE9) mice: A hypothesis on the role of cerebellum in Alzheimer's disease.
Alzheimers Dement. 2022 Dec 5. doi: 10.1002/alz.12853.
PubMed Abstract available

KUCUKALI F, Neumann A, Van Dongen J, De Pooter T, et al
Whole-exome rare-variant analysis of Alzheimer's disease and related biomarker traits.
Alzheimers Dement. 2022 Dec 4. doi: 10.1002/alz.12842.
PubMed Abstract available

CARLOS AF, Tosakulwong N, Weigand SD, Senjem ML, et al
TDP-43 pathology effect on volume and flortaucipir uptake in Alzheimer's disease.
Alzheimers Dement. 2022 Dec 4. doi: 10.1002/alz.12878.
PubMed Abstract available

MAZER NA, Hofmann C, Lott D, Gieschke R, et al
Development of a quantitative semi-mechanistic model of Alzheimer's disease based on the amyloid/tau/neurodegeneration framework (the Q-ATN model).
Alzheimers Dement. 2022 Dec 1. doi: 10.1002/alz.12877.
PubMed Abstract available

SUSHKO VV, Sushko VV
Use Acetazolamide in the Complex Therapy of Alzheimer's Disease.
Alzheimers Dement. 2022;18 Suppl 9:e059982.
PubMed Abstract available

HENDRIX SB, Nicodemus-Johnson J, Hogan NJ, Knowlton N, et al
Not sexy enough: the uphill battle faced by non-traditional treatments in the U.S. despite having the most compelling AD results to date.
Alzheimers Dement. 2022;18 Suppl 9:e068373.
PubMed Abstract available

COSE DS
An Innovative Approach to Empowering Care Partners Living with A Loved One Diagnosed with Younger-Onset Alzheimer's.
Alzheimers Dement. 2022;18 Suppl 9:e061257.
PubMed Abstract available

FIELDS BE, Boutilier JJ, Jolliff A, Elliott C, et al
Does Caregiver Education Level Influence Confidence in Care Budgeting and Planning for Persons Living with Alzheimer's Disease or Related Dementias?
Alzheimers Dement. 2022;18 Suppl 9:e068923.
PubMed Abstract available

MACKOWICZ M, Yee J, Clark LR, Wanninger E, et al
Dysphagia Evaluation in a Multidisciplinary VA Cognitive Care Clinic.
Alzheimers Dement. 2022;18 Suppl 9:e063955.
PubMed Abstract available

DIAZ-SANTOS M, Yanez JJ, Suarez PA
Alzheimer's Disease in Bilingual Latinos: Clinical Decisions for Diagnosis and Treatment Planning.
Alzheimers Dement. 2022;18 Suppl 9:e064253.
PubMed Abstract available

BLEKOU P, Sakka P, Leonti AA, Megagianni S, et al
The Greek Dementia Helpline: experience and impact.
Alzheimers Dement. 2022;18 Suppl 9:e061186.
PubMed Abstract available

VAN PHAN T, Praet J, Guarnieri R, Lowenthal E, et al
An Educational Platform about Current and Future Paradigms of Neuroimaging in the Management of Alzheimer's Disease.
Alzheimers Dement. 2022;18 Suppl 9:e065989.
PubMed Abstract available

MCGURIN NE, McCarthy L, Arsenault L, Showalter E, et al
Dementia Care Coordination: Evaluating a Program to Support Caregivers through Collaboration with the Alzheimer's Association and Health Care Partners.
Alzheimers Dement. 2022;18 Suppl 9:e059900.
PubMed Abstract available

REUBEN D, Panlilio M
Effects of an Alzheimer's and Dementia Care Co-management Program on Quality, Clinical Outcomes, and Utilization.
Alzheimers Dement. 2022;18 Suppl 9:e063939.
PubMed Abstract available

JOYCE JL, Caes D, Chapman S, Gottesman RT, et al
Screening for Memory Concerns at the Well-Woman Visit.
Alzheimers Dement. 2022;18 Suppl 9:e067894.
PubMed Abstract available

COSE DS
Supporting Youth With A Parent Who Is Living Younger-Onset Alzheimer's: A Crucial Component In Integrated Care.
Alzheimers Dement. 2022;18 Suppl 9:e062968.
PubMed Abstract available

BLEKOU P, Sakka P, Zoi P, Kalligeros N, et al
Tablet training at home for people with dementia and their caregivers during pandemic.
Alzheimers Dement. 2022;18 Suppl 9:e065713.
PubMed Abstract available

BORMANS K, Zwakhalen S
Using children's drawings as implicit measurements in future Alzheimer's research for the detection and alteration of negative stereotyping.
Alzheimers Dement. 2022;18 Suppl 9:e067593.
PubMed Abstract available

SPENSLEY SB
Identifying priorities and supporting ADRD researchers through Alzheimer's Disease Research Center Research Education Components.
Alzheimers Dement. 2022;18 Suppl 9:e062410.
PubMed Abstract available

SUPER N
Scaling Comprehensive Dementia Care.
Alzheimers Dement. 2022;18 Suppl 9:e063942.
PubMed Abstract available

MIRABNAHRAZAM G, Ma D, Beaulac C, Lee S, et al
Predicting Alzheimer's disease progression in healthy and MCI subjects using multi-modal deep learning approach.
Alzheimers Dement. 2022;18 Suppl 2:e060949.
PubMed Abstract available

HILSABECK RC, Keller JN, Henry ML, Toprac P, et al
Multidisciplinary collaboration to develop a digital health solution for early detection of cognitive decline in primary care.
Alzheimers Dement. 2022;18 Suppl 2:e067832.
PubMed Abstract available

KOLANKO MA, Soreq E, Lai H, Barnaghi P, et al
Clinically relevant monitoring of long-term night-time behaviour and physiology from the homes of people living with dementia.
Alzheimers Dement. 2022;18 Suppl 2:e068241.
PubMed Abstract available

WATERMEYER TJ, Butler J, Matterson E, Harper EG, et al
A digital biomarker for remote self-assessment of Alzheimer's Diseases: development and validation.
Alzheimers Dement. 2022;18 Suppl 2:e066066.
PubMed Abstract available

BEATTIE ZT, Gothard S, Barnes LL, Calloway S, et al
The Collaboration and Harmonization of Digital Biomarkers for Alzheimer's Research.
Alzheimers Dement. 2022;18 Suppl 2:e067984.
PubMed Abstract available

OHMAN F, Berron D, Skoog J, Bodin TH, et al
Smartphone-based long-term delayed memory performance is associated with the Preclinical Alzheimer's Cognitive Composite and CSF levels of beta-amyloid.
Alzheimers Dement. 2022;18 Suppl 2:e068015.
PubMed Abstract available

SCHUSSLER S, Zuschnegg J, Paletta L, Russegger S, et al
Experiences of people with Alzheimer's disease, relatives, and dementia trainers on the usability of a tablet-based dementia training.
Alzheimers Dement. 2022;18 Suppl 2:e062097.
PubMed Abstract available

MEYER T, Moro-Velazquez L, Motley S, Butala A, et al
Automatic Extraction of Oculographic Signals as Digital Biomarkers for Alzheimer's Disease.
Alzheimers Dement. 2022;18 Suppl 2:e066018.
PubMed Abstract available

BABATOPE EY, Rodriguez ML, Garcia-Vazquez MS, Alvaro Ramirez-Acosta A, et al
Recognizing human functional patterns in IADLs through hand detection and artificial intelligence.
Alzheimers Dement. 2022;18 Suppl 2:e064212.
PubMed Abstract available

FAVARO A, Motley S, Samus QM, Butala A, et al
Artificial Intelligence Tools to Evaluate Language and Speech Patterns in Alzheimer's Disease.
Alzheimers Dement. 2022;18 Suppl 2:e064913.
PubMed Abstract available

RANSON JM, Khleifat AA, Lyall DM, Newby D, et al
The Deep Dementia Phenotyping (DEMON) Network: A global platform for innovation using data science and artificial intelligence.
Alzheimers Dement. 2022;18 Suppl 2:e067308.
PubMed Abstract available

PARSAPOOR M
Towards Fair ML-based Language Assessment Methods for Detecting Alzheimer's Disease.
Alzheimers Dement. 2022;18 Suppl 2:e063426.
PubMed Abstract available

ROSSINI PM, Miraglia F, Vecchio F
Early dementia diagnosis, MCI-to-dementia risk prediction, and the role of machine learning methods for feature extraction from integrated biomarkers, in particular for EEG signal analysis.
Alzheimers Dement. 2022;18:2699-2706.
PubMed Abstract available

FOCKLER J, Ashford MT, Eichenbaum J, Howell T, et al
Remote blood collection from older adults in the Brain Health Registry for plasma biomarker and genetic analysis.
Alzheimers Dement. 2022;18:2627-2636.
PubMed Abstract available

MOSCOSO A, Karikari TK, Grothe MJ, Ashton NJ, et al
CSF biomarkers and plasma p-tau181 as predictors of longitudinal tau accumulation: Implications for clinical trial design.
Alzheimers Dement. 2022;18:2614-2626.
PubMed Abstract available

ZHU CW, Neugroschl J, Barnes LL, Sano M, et al
Racial/ethnic disparities in initiation and persistent use of anti-dementia medications.
Alzheimers Dement. 2022;18:2582-2592.
PubMed Abstract available

HANON O, Vidal JS, Lehmann S, Bombois S, et al
Plasma amyloid beta predicts conversion to dementia in subjects with mild cognitive impairment: The BALTAZAR study.
Alzheimers Dement. 2022;18:2537-2550.
PubMed Abstract available

WANG J, Dove A, Song R, Qi X, et al
Poor pulmonary function is associated with mild cognitive impairment, its progression to dementia, and brain pathologies: A community-based cohort study.
Alzheimers Dement. 2022;18:2551-2559.
PubMed Abstract available

GODRICH D, Martin ER, Schellenberg G, Pericak-Vance MA, et al
Neuropathological lesions and their contribution to dementia and cognitive impairment in a heterogeneous clinical population.
Alzheimers Dement. 2022;18:2403-2412.
PubMed Abstract available

SHAH J, Gao F, Li B, Ghisays V, et al
Deep residual inception encoder-decoder network for amyloid PET harmonization.
Alzheimers Dement. 2022;18:2448-2457.
PubMed Abstract available

BHARTHUR SANJAY A, Patania A, Yan X, Svaldi D, et al
Characterization of gene expression patterns in mild cognitive impairment using a transcriptomics approach and neuroimaging endophenotypes.
Alzheimers Dement. 2022;18:2493-2508.
PubMed Abstract available

November 2022

GUEORGUIEVA I, Chua L, Willis BA, Sims JR, et al
Disease progression model using the integrated Alzheimer's Disease Rating Scale.
Alzheimers Dement. 2022 Nov 30. doi: 10.1002/alz.12876.
PubMed Abstract available

CASTRANIO EL, Hasel P, Haure-Mirande JV, Ramirez Jimenez AV, et al
Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer's disease.
Alzheimers Dement. 2022 Nov 30. doi: 10.1002/alz.12821.
PubMed Abstract available

FERRELL PB, Fillit H, Neumann PJ, Wall JK, et al
Toward comprehensive value assessment for Alzheimer's disease innovations.
Alzheimers Dement. 2022 Nov 25. doi: 10.1002/alz.12874.
PubMed Abstract available

STEWARD A, Biel D, Brendel M, Dewenter A, et al
Functional network segregation is associated with attenuated tau spreading in Alzheimer's disease.
Alzheimers Dement. 2022 Nov 25. doi: 10.1002/alz.12867.
PubMed Abstract available

DOHERTY JM, Murphy SA, Bayat S, Wisch JK, et al
Adverse driving behaviors increase over time as a function of preclinical Alzheimer's disease biomarkers.
Alzheimers Dement. 2022 Nov 23. doi: 10.1002/alz.12852.
PubMed Abstract available

CAREY A, Fossati S
Hypertension and hyperhomocysteinemia as modifiable risk factors for Alzheimer's disease and dementia: New evidence, potential therapeutic strategies, and biomarkers.
Alzheimers Dement. 2022 Nov 19. doi: 10.1002/alz.12871.
PubMed Abstract available

KARPOUZIAN-ROGERS T, Ho E, Novack M, Chinkers M, et al
Baseline characterization of the ARMADA (Assessing Reliable Measurement in Alzheimer's Disease) study cohorts.
Alzheimers Dement. 2022 Nov 17. doi: 10.1002/alz.12816.
PubMed Abstract available

GOLDHARDT O, Freiberger R, Dreyer T, Wilner L, et al
Herpes simplex virus alters Alzheimer's disease biomarkers - A hypothesis paper.
Alzheimers Dement. 2022 Nov 17. doi: 10.1002/alz.12834.
PubMed Abstract available

HUANG J, Stein TD, Wang Y, Ang TFA, et al
Blood levels of MCP-1 modulate the genetic risks of Alzheimer's disease mediated by HLA-DRB1 and APOE for Alzheimer's disease.
Alzheimers Dement. 2022 Nov 17. doi: 10.1002/alz.12851.
PubMed Abstract available

POLSINELLI AJ, Logan PE, Lane KA, Manchella MK, et al
APOE epsilon4 carrier status and sex differentiate rates of cognitive decline in early- and late-onset Alzheimer's disease.
Alzheimers Dement. 2022 Nov 17. doi: 10.1002/alz.12831.
PubMed Abstract available

PANG M, Zhu L, Gabelle A, Gafson AR, et al
Toward the end of a controversy on the effect of reduction in brain amyloid levels on change in cognitive and functional decline in Alzheimer's disease-Reply to a letter.
Alzheimers Dement. 2022 Nov 16. doi: 10.1002/alz.12864.
PubMed

REIMAN EM, Pruzin JJ, Rios-Romenets S, Brown C, et al
A public resource of baseline data from the Alzheimer's Prevention Initiative Autosomal-Dominant Alzheimer's Disease Trial.
Alzheimers Dement. 2022 Nov 14. doi: 10.1002/alz.12843.
PubMed Abstract available

MINDT MR, Okonkwo O, Weiner MW, Veitch DP, et al
Improving generalizability and study design of Alzheimer's disease cohort studies in the United States by including under-represented populations.
Alzheimers Dement. 2022 Nov 13. doi: 10.1002/alz.12823.
PubMed Abstract available

CHEN XQ, Zuo X, Becker A, Head E, et al
Reduced synaptic proteins and SNARE complexes in Down syndrome with Alzheimer's disease and the Dp16 mouse Down syndrome model: Impact of APP gene dose.
Alzheimers Dement. 2022 Nov 12. doi: 10.1002/alz.12835.
PubMed Abstract available

HSHIEH TT, Gou RY, Jones RN, Leslie DL, et al
One-year Medicare costs associated with delirium in older hospitalized patients with and without Alzheimer's disease dementia and related disorders.
Alzheimers Dement. 2022 Nov 10. doi: 10.1002/alz.12826.
PubMed Abstract available

HUANG X, Li Y, Fowler C, Doecke JD, et al
Leukocyte surface biomarkers implicate deficits of innate immunity in sporadic Alzheimer's disease.
Alzheimers Dement. 2022 Nov 9. doi: 10.1002/alz.12813.
PubMed Abstract available

WU R, Tripathy S, Menon V, Yu L, et al
Fragmentation of rest periods, astrocyte activation, and cognitive decline in older adults with and without Alzheimer's disease.
Alzheimers Dement. 2022 Nov 6. doi: 10.1002/alz.12817.
PubMed Abstract available

ZHANG P, Hou Y, Tu W, Campbell N, et al
Population-based discovery and Mendelian randomization analysis identify telmisartan as a candidate medicine for Alzheimer's disease in African Americans.
Alzheimers Dement. 2022 Nov 4. doi: 10.1002/alz.12819.
PubMed Abstract available

Alzheimer's Association takes on leadership role in landmark Alzheimer's biomarker study.
Alzheimers Dement. 2022 Nov 4. doi: 10.1002/alz.12873.
PubMed

KYLE S, Youran T, Thomas W, Liuhua S, et al
The effect of race and co-morbidities on Alzheimer's disease based on Medicare data.
Alzheimers Dement. 2022 Nov 3. doi: 10.1002/alz.12838.
PubMed Abstract available

GILLIS C, Montenigro P, Nejati M, Maserejian N, et al
Estimating prevalence of early Alzheimer's disease in the United States, accounting for racial and ethnic diversity.
Alzheimers Dement. 2022 Nov 2. doi: 10.1002/alz.12822.
PubMed Abstract available

Improving community health-care systems' early detection of cognitive decline and dementia.
Alzheimers Dement. 2022;18:2375-2381.
PubMed Abstract available

TEMP AGM, Ly A, van Doorn J, Wagenmakers EJ, et al
A Bayesian perspective on Biogen's aducanumab trial.
Alzheimers Dement. 2022;18:2341-2351.
PubMed Abstract available

LECCA D, Jung YJ, Scerba MT, Hwang I, et al
Role of chronic neuroinflammation in neuroplasticity and cognitive function: A hypothesis.
Alzheimers Dement. 2022;18:2327-2340.
PubMed Abstract available

HEGAZY SH, Thomassen JQ, Rasmussen IJ, Nordestgaard BG, et al
C-reactive protein levels and risk of dementia-Observational and genetic studies of 111,242 individuals from the general population.
Alzheimers Dement. 2022;18:2262-2271.
PubMed Abstract available

BHASIN H, Agrawal RK
Triploid genetic algorithm for convolutional neural network-based diagnosis of mild cognitive impairment.
Alzheimers Dement. 2022;18:2283-2291.
PubMed Abstract available

KULLER LH, Snitz BE, Hughes TM, Chang Y, et al
Low untreated systolic blood pressure over 18 years is associated with survival free of dementia age 90.
Alzheimers Dement. 2022;18:2176-2187.
PubMed Abstract available

PADOVANI A, Canale A, Schiavon L, Masciocchi S, et al
Is amyloid involved in acute neuroinflammation? A CSF analysis in encephalitis.
Alzheimers Dement. 2022;18:2167-2175.
PubMed Abstract available

BELLEVILLE S, Cloutier S, Mellah S, Willis S, et al
Is more always better? Dose effect in a multidomain intervention in older adults at risk of dementia.
Alzheimers Dement. 2022;18:2140-2150.
PubMed Abstract available

October 2022

HANDELS RLH, Green C, Gustavsson A, Herring WL, et al
Cost-effectiveness models for Alzheimer's disease and related dementias: IPECAD modeling workshop cross-comparison challenge.
Alzheimers Dement. 2022 Oct 25. doi: 10.1002/alz.12811.
PubMed Abstract available

NOVOTNY BC, Fernandez MV, Wang C, Budde JP, et al
Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer's disease brains.
Alzheimers Dement. 2022 Oct 17. doi: 10.1002/alz.12800.
PubMed Abstract available

NILSSON J, Cousins KAQ, Gobom J, Portelius E, et al
Cerebrospinal fluid biomarker panel of synaptic dysfunction in Alzheimer's disease and other neurodegenerative disorders.
Alzheimers Dement. 2022 Oct 14. doi: 10.1002/alz.12809.
PubMed Abstract available

AAIC((R)) 2022: The promise of Alzheimer's research.
Alzheimers Dement. 2022 Oct 12. doi: 10.1002/alz.12829.
PubMed

HARERIMANA NV, Paliwali D, Romero-Molina C, Bennett DA, et al
The role of mitochondrial genome abundance in Alzheimer's disease.
Alzheimers Dement. 2022 Oct 12. doi: 10.1002/alz.12812.
PubMed Abstract available

LIEBERMAN OJ, Lee S, Zabinski J
Donepezil treatment is associated with improved outcomes in critically ill dementia patients via a reduction in delirium.
Alzheimers Dement. 2022 Oct 11. doi: 10.1002/alz.12807.
PubMed Abstract available

WEINER MW, Veitch DP, Miller MJ, Aisen PS, et al
Increasing participant diversity in AD research: Plans for digital screening, blood testing, and a community-engaged approach in the Alzheimer's Disease Neuroimaging Initiative 4.
Alzheimers Dement. 2022 Oct 9. doi: 10.1002/alz.12797.
PubMed Abstract available

STEPHAN BCM, Gaughan DM, Edland S, Gudnason V, et al
Mid- and later-life risk factors for predicting neuropathological brain changes associated with Alzheimer's and vascular dementia: The Honolulu Asia Aging Study and the Age, Gene/Environment Susceptibility-Reykjavik Study.
Alzheimers Dement. 2022 Oct 4. doi: 10.1002/alz.12762.
PubMed Abstract available

NUYTEMANS K, Lipkin Vasquez M, Wang L, Van Booven D, et al
Identifying differential regulatory control of APOE varepsilon4 on African versus European haplotypes as potential therapeutic targets.
Alzheimers Dement. 2022;18:1930-1942.
PubMed Abstract available

CORNELL PY, Zhang W, Smith L, Rahman M, et al
Memory care reduces nursing home admissions among assisted-living residents with dementia.
Alzheimers Dement. 2022;18:1880-1888.
PubMed Abstract available

MARRIOTT RJ, Murray K, Flicker L, Hankey GJ, et al
Lower serum testosterone concentrations are associated with a higher incidence of dementia in men: The UK Biobank prospective cohort study.
Alzheimers Dement. 2022;18:1907-1918.
PubMed Abstract available

PINK A, Krell-Roesch J, Syrjanen JA, Vassilaki M, et al
A longitudinal investigation of Abeta, anxiety, depression, and mild cognitive impairment.
Alzheimers Dement. 2022;18:1824-1831.
PubMed Abstract available

JANSSEN O, Jansen WJ, Vos SJB, Boada M, et al
Characteristics of subjective cognitive decline associated with amyloid positivity.
Alzheimers Dement. 2022;18:1832-1845.
PubMed Abstract available

SCHLIEP KC, Ju S, Foster NL, Smith KR, et al
How good are medical and death records for identifying dementia?
Alzheimers Dement. 2022;18:1812-1823.
PubMed Abstract available

GAO Y, Felsky D, Reyes-Dumeyer D, Sariya S, et al
Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance.
Alzheimers Dement. 2022;18:1797-1811.
PubMed Abstract available

September 2022

HARTZ SM, Mozersky J, Schindler SE, Linnenbringer E, et al
A flexible modeling approach for biomarker-based computation of absolute risk of Alzheimer's disease dementia.
Alzheimers Dement. 2022 Sep 30. doi: 10.1002/alz.12781.
PubMed Abstract available

SCHAEVERBEKE J, Tome SO, Ronisz A, Ospitalieri S, et al
Neuronal loss of the nucleus basalis of Meynert in primary progressive aphasia is associated with Alzheimer's disease neuropathological changes.
Alzheimers Dement. 2022 Sep 28. doi: 10.1002/alz.12794.
PubMed Abstract available

KATABATHULA S, Davis PB, Xu R
Comorbidity-driven multi-modal subtype analysis in mild cognitive impairment of Alzheimer's disease.
Alzheimers Dement. 2022 Sep 27. doi: 10.1002/alz.12792.
PubMed Abstract available

WEAVER DF
Alzheimer's disease as an innate autoimmune disease (AD(2) ): A new molecular paradigm.
Alzheimers Dement. 2022 Sep 27. doi: 10.1002/alz.12789.
PubMed Abstract available

LIU KY, Thambisetty M, Howard R
How can secondary dementia prevention trials of Alzheimer's disease be clinically meaningful?
Alzheimers Dement. 2022 Sep 26. doi: 10.1002/alz.12788.
PubMed Abstract available

PICHET BINETTE A, Janelidze S, Cullen N, Dage JL, et al
Confounding factors of Alzheimer's disease plasma biomarkers and their impact on clinical performance.
Alzheimers Dement. 2022 Sep 24. doi: 10.1002/alz.12787.
PubMed Abstract available

VETELEANU A, Pape S, Davies K, Kodosaki E, et al
Complement dysregulation and Alzheimer's disease in Down syndrome.
Alzheimers Dement. 2022 Sep 23. doi: 10.1002/alz.12799.
PubMed Abstract available

YIN L, Zhou J, Li T, Wang X, et al
Inhibition of the dopamine transporter promotes lysosome biogenesis and ameliorates Alzheimer's disease-like symptoms in mice.
Alzheimers Dement. 2022 Sep 21. doi: 10.1002/alz.12776.
PubMed Abstract available

DEPYPERE H, Vergallo A, Lemercier P, Lista S, et al
Menopause hormone therapy significantly alters pathophysiological biomarkers of Alzheimer's disease.
Alzheimers Dement. 2022 Sep 15. doi: 10.1002/alz.12759.
PubMed Abstract available

Alzheimer's Association launches ALZ-NET: A long-term data collection and sharing network for new treatments.
Alzheimers Dement. 2022 Sep 12. doi: 10.1002/alz.12782.
PubMed

JUTTEN RJ, Papp KV, Hendrix S, Ellison N, et al
Why a clinical trial is as good as its outcome measure: A framework for the selection and use of cognitive outcome measures for clinical trials of Alzheimer's disease.
Alzheimers Dement. 2022 Sep 10. doi: 10.1002/alz.12773.
PubMed Abstract available

DALY T
The conundrum of the AD continuum.
Alzheimers Dement. 2022 Sep 8. doi: 10.1002/alz.12783.
PubMed

MATTKE S, Correa Dos Santos Filho O, Hanson M, Mateus EF, et al
Preparedness of the Brazilian health-care system to provide access to a disease-modifying Alzheimer's disease treatment.
Alzheimers Dement. 2022 Sep 5. doi: 10.1002/alz.12778.
PubMed Abstract available

SKILLBACK T, Blennow K, Zetterberg H, Skoog J, et al
Slowing gait speed precedes cognitive decline by several years.
Alzheimers Dement. 2022;18:1667-1676.
PubMed Abstract available

August 2022

JIANG L, Li JC, Tang BS, Guo JF, et al
Lack of bidirectional association between age-related macular degeneration and Alzheimer's disease: A Mendelian randomization study.
Alzheimers Dement. 2022 Aug 25. doi: 10.1002/alz.12775.
PubMed Abstract available

LUTZ MW, Khachaturian AS, Zetterberg H, Blennow K, et al
Biomarkers of Alzheimer syndrome and related dementias: A&D author's guide.
Alzheimers Dement. 2022 Aug 25. doi: 10.1002/alz.12772.
PubMed

FRIKKE-SCHMIDT R, Hegazy SH, Rasmussen IJ, Nordestgaard BG, et al
Observational and genetic studies of C-reactive protein levels and risk of Alzheimer's disease.
Alzheimers Dement. 2022 Aug 21. doi: 10.1002/alz.12742.
PubMed

RAFII MS, Sperling RA, Donohue MC, Zhou J, et al
The AHEAD 3-45 Study: Design of a prevention trial for Alzheimer's disease.
Alzheimers Dement. 2022 Aug 15. doi: 10.1002/alz.12748.
PubMed Abstract available

PALMQVIST S, Stomrud E, Cullen N, Janelidze S, et al
An accurate fully automated panel of plasma biomarkers for Alzheimer's disease.
Alzheimers Dement. 2022 Aug 11. doi: 10.1002/alz.12751.
PubMed Abstract available

LANGBAUM JB, Zissimopoulos J, Au R, Bose N, et al
Recommendations to address key recruitment challenges of Alzheimer's disease clinical trials.
Alzheimers Dement. 2022 Aug 10. doi: 10.1002/alz.12737.
PubMed Abstract available

OLCHANSKI N, Daly AT, Zhu Y, Breslau R, et al
Alzheimer's disease medication use and adherence patterns by race and ethnicity.
Alzheimers Dement. 2022 Aug 8. doi: 10.1002/alz.12753.
PubMed Abstract available

SCHINDLER SE, Li Y, Li M, Despotis A, et al
Using Alzheimer's disease blood tests to accelerate clinical trial enrollment.
Alzheimers Dement. 2022 Aug 7. doi: 10.1002/alz.12754.
PubMed Abstract available

WANG J, Guo C, Meng Z, Zwan MD, et al
Testing the link between isoaspartate and Alzheimer's disease etiology.
Alzheimers Dement. 2022 Aug 4. doi: 10.1002/alz.12735.
PubMed Abstract available

MOLONEY CM, Labuzan SA, Crook JE, Siddiqui H, et al
Phosphorylated tau sites that are elevated in Alzheimer's disease fluid biomarkers are visualized in early neurofibrillary tangle maturity levels in the post mortem brain.
Alzheimers Dement. 2022 Aug 3. doi: 10.1002/alz.12749.
PubMed Abstract available

PETERSEN RC, Graf A, Carrillo MC, Weber CJ, et al
Current understanding of AD pathophysiology and impact of amyloid beta-targeted treatments on biomarkers and clinical endpoints.
Alzheimers Dement. 2022;18:1586.
PubMed

HACHINSKI V
The comprehensive, customized, cost-effective approach (CCCAP) to prevention of dementia.
Alzheimers Dement. 2022;18:1565-1568.
PubMed Abstract available

LENNON JC, Aita SL, Bene VAD, Rhoads T, et al
Black and White individuals differ in dementia prevalence, risk factors, and symptomatic presentation.
Alzheimers Dement. 2022;18:1461-1471.
PubMed Abstract available

PERLUIGI M, Picca A, Montanari E, Calvani R, et al
Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal-derived extracellular vesicles.
Alzheimers Dement. 2022;18:1498-1510.
PubMed Abstract available

PAJEWSKI NM, Elahi FM, Tamura MK, Hinman JD, et al
Plasma amyloid beta, neurofilament light chain, and total tau in the Systolic Blood Pressure Intervention Trial (SPRINT).
Alzheimers Dement. 2022;18:1472-1483.
PubMed Abstract available

July 2022

HANSSON O, Edelmayer RM, Boxer AL, Carrillo MC, et al
The Alzheimer's Association appropriate use recommendations for blood biomarkers in Alzheimer's disease.
Alzheimers Dement. 2022 Jul 31. doi: 10.1002/alz.12756.
PubMed Abstract available

NOTARIANNI E
Risk association between midlife lipid and glucose levels and future Alzheimer's disease.
Alzheimers Dement. 2022 Jul 28. doi: 10.1002/alz.12738.
PubMed

LOZUPONE M, Imbimbo BP, Balducci C, Lo Vecchio F, et al
Does the imbalance in the apolipoprotein E isoforms underlie the pathophysiological process of sporadic Alzheimer's disease?
Alzheimers Dement. 2022 Jul 28. doi: 10.1002/alz.12728.
PubMed Abstract available

MAHAPATRA G, Gao Z, Bateman JR 3rd, Lockhart SN, et al
Blood-based bioenergetic profiling reveals differences in mitochondrial function associated with cognitive performance and Alzheimer's disease.
Alzheimers Dement. 2022 Jul 23. doi: 10.1002/alz.12731.
PubMed Abstract available

CHATTERJEE P, Pedrini S, Doecke JD, Thota R, et al
Plasma Abeta42/40 ratio, p-tau181, GFAP, and NfL across the Alzheimer's disease continuum: A cross-sectional and longitudinal study in the AIBL cohort.
Alzheimers Dement. 2022 Jul 21. doi: 10.1002/alz.12724.
PubMed Abstract available

BEYER L, Stocker H, Rujescu D, Holleczek B, et al
Amyloid-beta misfolding and GFAP predict risk of clinical Alzheimer's disease diagnosis within 17 years.
Alzheimers Dement. 2022 Jul 19. doi: 10.1002/alz.12745.
PubMed Abstract available

LIU H, Xie Y, Wang X, Abboud MI, et al
Exploring links between 2-oxoglutarate-dependent oxygenases and Alzheimer's disease.
Alzheimers Dement. 2022 Jul 19. doi: 10.1002/alz.12733.
PubMed Abstract available

BATRA R, Arnold M, Worheide MA, Allen M, et al
The landscape of metabolic brain alterations in Alzheimer's disease.
Alzheimers Dement. 2022 Jul 13. doi: 10.1002/alz.12714.
PubMed Abstract available

WANG JT, Xu G, Ren RJ, Wang Y, et al
The impacts of health insurance and resource on the burden of Alzheimer's disease and related dementias in the world population.
Alzheimers Dement. 2022 Jul 12. doi: 10.1002/alz.12730.
PubMed Abstract available

LIN Z, Lim C, Jiang D, Soldan A, et al
Longitudinal changes in brain oxygen extraction fraction (OEF) in older adults: Relationship to markers of vascular and Alzheimer's pathology.
Alzheimers Dement. 2022 Jul 6. doi: 10.1002/alz.12727.
PubMed Abstract available

TIAN C, Stewart T, Hong Z, Guo Z, et al
Blood extracellular vesicles carrying synaptic function- and brain-related proteins as potential biomarkers for Alzheimer's disease.
Alzheimers Dement. 2022 Jul 2. doi: 10.1002/alz.12723.
PubMed Abstract available

SALVADO G, Ferreira D, Operto G, Cumplido-Mayoral I, et al
The protective gene dose effect of the APOE epsilon2 allele on gray matter volume in cognitively unimpaired individuals.
Alzheimers Dement. 2022;18:1383-1395.
PubMed Abstract available

KATSEL P, Fam P, Tan W, Khan S, et al
Engagement of vascular early response genes typifies mild cognitive impairment.
Alzheimers Dement. 2022;18:1357-1369.
PubMed Abstract available

June 2022

CHUNG J, Das A, Sun X, Sobreira DR, et al
Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women.
Alzheimers Dement. 2022 Jun 30. doi: 10.1002/alz.12719.
PubMed Abstract available

WEINER MW, Harvey D, Landau SM, Veitch DP, et al
Traumatic brain injury and post-traumatic stress disorder are not associated with Alzheimer's disease pathology measured with biomarkers.
Alzheimers Dement. 2022 Jun 29. doi: 10.1002/alz.12712.
PubMed Abstract available

ABDULRAHMAN H, van Dalen JW, den Brok M, Latimer CS, et al
Hypertension and Alzheimer's disease pathology at autopsy: A systematic review.
Alzheimers Dement. 2022 Jun 27. doi: 10.1002/alz.12707.
PubMed Abstract available

GILMORE-BYKOVSKYI A, Griffin JM, Mueller KD, Parnia S, et al
Toward harmonization of strategies for investigating lucidity in AD/ADRD: A preliminary research framework.
Alzheimers Dement. 2022;19:343-52.
PubMed Abstract available

WINGO TS, Gerasimov ES, Canon SM, Lah JJ, et al
Alzheimer's disease genetic burden is associated with mid-life depression among persons with normal cognition.
Alzheimers Dement. 2022 Jun 21. doi: 10.1002/alz.12716.
PubMed Abstract available

CULLEN NC, Janelidze S, Mattsson-Carlgren N, Palmqvist S, et al
Test-retest variability of plasma biomarkers in Alzheimer's disease and its effects on clinical prediction models.
Alzheimers Dement. 2022 Jun 14. doi: 10.1002/alz.12706.
PubMed Abstract available

DELVENNE A, Gobom J, Tijms B, Bos I, et al
Cerebrospinal fluid proteomic profiling of individuals with mild cognitive impairment and suspected non-Alzheimer's disease pathophysiology.
Alzheimers Dement. 2022 Jun 14. doi: 10.1002/alz.12713.
PubMed Abstract available

SINGH NA, Tosakulwong N, Graff-Radford J, Machulda MM, et al
APOE epsilon4 influences medial temporal atrophy and tau deposition in atypical Alzheimer's disease.
Alzheimers Dement. 2022 Jun 12. doi: 10.1002/alz.12711.
PubMed Abstract available

RISCHEL EB, Gejl M, Brock B, Rungby J, et al
In Alzheimer's disease, amyloid beta accumulation is a protective mechanism that ultimately fails.
Alzheimers Dement. 2022 Jun 8. doi: 10.1002/alz.12701.
PubMed Abstract available

GAO F, Lv X, Dai L, Wang Q, et al
A combination model of AD biomarkers revealed by machine learning precisely predicts Alzheimer's dementia: China Aging and Neurodegenerative Initiative (CANDI) study.
Alzheimers Dement. 2022 Jun 6. doi: 10.1002/alz.12700.
PubMed Abstract available

GUSTAVSSON A, Norton N, Fast T, Frolich L, et al
Global estimates on the number of persons across the Alzheimer's disease continuum.
Alzheimers Dement. 2022 Jun 2. doi: 10.1002/alz.12694.
PubMed Abstract available

SAWA M, Overk C, Becker A, Derse D, et al
Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model.
Alzheimers Dement. 2022;18:1203-1234.
PubMed Abstract available

SYRJANEN JA, Campbell MR, Algeciras-Schimnich A, Vemuri P, et al
Associations of amyloid and neurodegeneration plasma biomarkers with comorbidities.
Alzheimers Dement. 2022;18:1128-1140.
PubMed Abstract available

LIU L, Kwak H, Lawton TL, Jin SX, et al
An ultra-sensitive immunoassay detects and quantifies soluble Abeta oligomers in human plasma.
Alzheimers Dement. 2022;18:1186-1202.
PubMed Abstract available

SANZ-BLASCO R, Ruiz-Sanchez de Leon JM, Avila-Villanueva M, Valenti-Soler M, et al
Transition from mild cognitive impairment to normal cognition: Determining the predictors of reversion with multi-state Markov models.
Alzheimers Dement. 2022;18:1177-1185.
PubMed Abstract available

May 2022

VOGLEIN J, Franzmeier N, Morris JC, Dieterich M, et al
Patterns and implications of neurological examination findings in autosomal dominant Alzheimer disease.
Alzheimers Dement. 2022 May 24. doi: 10.1002/alz.12684.
PubMed Abstract available

HU Y, Zhang Y, Zhang H, Gao S, et al
Mendelian randomization highlights causal association between genetically increased C-reactive protein levels and reduced Alzheimer's disease risk.
Alzheimers Dement. 2022 May 22. doi: 10.1002/alz.12687.
PubMed

LUO J, Thomassen JQ, Hegazy SH, Rasmussen IJ, et al
Reply to "Mendelian randomization highlights causal association between genetically increased C-reactive protein levels and reduced Alzheimer's disease risk".
Alzheimers Dement. 2022 May 22. doi: 10.1002/alz.12688.
PubMed

ASHLEIGH T, Swerdlow RH, Beal MF
The role of mitochondrial dysfunction in Alzheimer's disease pathogenesis.
Alzheimers Dement. 2022 May 6. doi: 10.1002/alz.12683.
PubMed Abstract available

SEXTON C, Snyder H, Beher D, Boxer AL, et al
Current directions in tau research: Highlights from Tau 2020.
Alzheimers Dement. 2022;18:988-1007.
PubMed Abstract available

IMBIMBO BP, Ippati S, Watling M, Balducci C, et al
A critical appraisal of tau-targeting therapies for primary and secondary tauopathies.
Alzheimers Dement. 2022;18:1008-1037.
PubMed Abstract available

PERRY BL, McConnell WR, Coleman ME, Roth AR, et al
Why the cognitive "fountain of youth" may be upstream: Pathways to dementia risk and resilience through social connectedness.
Alzheimers Dement. 2022;18:934-941.
PubMed Abstract available

April 2022

CHANG R, Trushina E, Zhu K, Zaidi SSA, et al
Predictive metabolic networks reveal sex- and APOE genotype-specific metabolic signatures and drivers for precision medicine in Alzheimer's disease.
Alzheimers Dement. 2022 Apr 28. doi: 10.1002/alz.12675.
PubMed Abstract available

PARK SY, Setiawan VW, White LR, Wu AH, et al
Modifying effects of race and ethnicity and APOE on the association of physical activity with risk of Alzheimer's disease and related dementias.
Alzheimers Dement. 2022 Apr 27. doi: 10.1002/alz.12677.
PubMed Abstract available

JESSEN F, Wolfsgruber S, Kleineindam L, Spottke A, et al
Subjective cognitive decline and stage 2 of Alzheimer disease in patients from memory centers.
Alzheimers Dement. 2022 Apr 22. doi: 10.1002/alz.12674.
PubMed Abstract available

QUAN L, Moreno-Gonzalez I, Xie Z, Gamez N, et al
A near-infrared probe for detecting and interposing amyloid beta oligomerization in early Alzheimer's disease.
Alzheimers Dement. 2022 Apr 18. doi: 10.1002/alz.12673.
PubMed Abstract available

TJANDRA D, Migrino RQ, Giordani B, Wiens J, et al
Use of blood pressure measurements extracted from the electronic health record in predicting Alzheimer's disease: A retrospective cohort study at two medical centers.
Alzheimers Dement. 2022 Apr 16. doi: 10.1002/alz.12676.
PubMed Abstract available

TA PARK VM, Meyer OL, Tsoh JY, Kanaya AM, et al
The Collaborative Approach for Asian Americans and Pacific Islanders Research and Education (CARE): A recruitment registry for Alzheimer's disease and related dementias, aging, and caregiver-related research.
Alzheimers Dement. 2022 Apr 14. doi: 10.1002/alz.12667.
PubMed Abstract available

MARTINEZ AE, Weissberger G, Kuklenyik Z, He X, et al
The small HDL particle hypothesis of Alzheimer's disease.
Alzheimers Dement. 2022 Apr 13. doi: 10.1002/alz.12649.
PubMed Abstract available

MIELKE MM, Aggarwal NT, Vila-Castelar C, Agarwal P, et al
Consideration of sex and gender in Alzheimer's disease and related disorders from a global perspective.
Alzheimers Dement. 2022 Apr 8. doi: 10.1002/alz.12662.
PubMed Abstract available

WANG Y, Li M, Kazis LE, Xia W, et al
Clinical outcomes of COVID-19 infection among patients with Alzheimer's disease or mild cognitive impairment.
Alzheimers Dement. 2022 Apr 4. doi: 10.1002/alz.12665.
PubMed Abstract available

FRUIJTIER AD, van der Schaar J, van Maurik IS, Zwan MD, et al
Identifying best practices for disclosure of amyloid imaging results: A randomized controlled trial.
Alzheimers Dement. 2022 Apr 2. doi: 10.1002/alz.12630.
PubMed Abstract available

LUCKETT PH, Chen C, Gordon BA, Wisch J, et al
Biomarker clustering in autosomal dominant Alzheimer's disease.
Alzheimers Dement. 2022 Apr 1. doi: 10.1002/alz.12661.
PubMed Abstract available

NEUPANE A, Lenny B, Budde JP, Wang F, et al
Replication study of AD-associated rare variants.
Alzheimers Dement. 2022;18:858-862.
PubMed

AKINYEMI RO, Yaria J, Ojagbemi A, Guerchet M, et al
Dementia in Africa: Current evidence, knowledge gaps, and future directions.
Alzheimers Dement. 2022;18:790-809.
PubMed Abstract available

MURA T, Coley N, Amieva H, Berr C, et al
Cognitive decline as an outcome and marker of progression toward dementia, in early preventive trials.
Alzheimers Dement. 2022;18:676-687.
PubMed Abstract available

LINDBOHM JV, Mars N, Walker KA, Singh-Manoux A, et al
Plasma proteins, cognitive decline, and 20-year risk of dementia in the Whitehall II and Atherosclerosis Risk in Communities studies.
Alzheimers Dement. 2022;18:612-624.
PubMed Abstract available

POURHADI N, Morch LS, Holm EA, Torp-Pedersen CT, et al
Vaginal estrogen and association with dementia: A nationwide population-based study.
Alzheimers Dement. 2022;18:625-634.
PubMed Abstract available

MIELKE MM, Aakre JA, Algeciras-Schimnich A, Proctor NK, et al
Comparison of CSF phosphorylated tau 181 and 217 for cognitive decline.
Alzheimers Dement. 2022;18:602-611.
PubMed Abstract available

CASANOVA R, Hsu FC, Barnard RT, Anderson AM, et al
Comparing data-driven and hypothesis-driven MRI-based predictors of cognitive impairment in individuals from the Atherosclerosis Risk in Communities (ARIC) study.
Alzheimers Dement. 2022;18:561-571.
PubMed Abstract available

YANG HS, Zhang C, Carlyle BC, Zhen SY, et al
Plasma IL-12/IFN-gamma axis predicts cognitive trajectories in cognitively unimpaired older adults.
Alzheimers Dement. 2022;18:645-653.
PubMed Abstract available

March 2022

BRODY M, Agronin M, Herskowitz BJ, Bookheimer SY, et al
Results and insights from a phase I clinical trial of Lomecel-B for Alzheimer's disease.
Alzheimers Dement. 2022 Mar 31. doi: 10.1002/alz.12651.
PubMed Abstract available

SUNDERLAND KM, Beaton D, Arnott SR, Kleinstiver P, et al
Characteristics of the Ontario Neurodegenerative Disease Research Initiative cohort.
Alzheimers Dement. 2022 Mar 30. doi: 10.1002/alz.12632.
PubMed Abstract available

ZHANG X, Tong T, Chang A, Ang TFA, et al
Midlife lipid and glucose levels are associated with Alzheimer's disease.
Alzheimers Dement. 2022 Mar 23. doi: 10.1002/alz.12641.
PubMed Abstract available

JACOBS HIL, Becker JA, Kwong K, Munera D, et al
Waning locus coeruleus integrity precedes cortical tau accrual in preclinical autosomal dominant Alzheimer's disease.
Alzheimers Dement. 2022 Mar 17. doi: 10.1002/alz.12656.
PubMed Abstract available

LI P, Gao L, Yu L, Zheng X, et al
Daytime napping and Alzheimer's dementia: A potential bidirectional relationship.
Alzheimers Dement. 2022 Mar 17. doi: 10.1002/alz.12636.
PubMed Abstract available

COE NB, White L, Oney M, Basu A, et al
Public spending on acute and long-term care for Alzheimer's disease and related dementias.
Alzheimers Dement. 2022 Mar 16. doi: 10.1002/alz.12657.
PubMed Abstract available

NITCHINGHAM A, Pereira JV, Wegner EA, Oxenham V, et al
Regional cerebral hypometabolism on 18F-FDG PET/CT scan in delirium is independent of acute illness and dementia.
Alzheimers Dement. 2022 Mar 15. doi: 10.1002/alz.12604.
PubMed Abstract available

2022 Alzheimer's disease facts and figures.
Alzheimers Dement. 2022 Mar 14. doi: 10.1002/alz.12638.
PubMed Abstract available

LIU L, Lauro BM, He A, Lee H, et al
Identification of the Abeta37/42 peptide ratio in CSF as an improved Abeta biomarker for Alzheimer's disease.
Alzheimers Dement. 2022 Mar 12. doi: 10.1002/alz.12646.
PubMed Abstract available

WINDER Z, Sudduth TL, Anderson S, Patel E, et al
Examining the association between blood-based biomarkers and human post mortem neuropathology in the University of Kentucky Alzheimer's Disease Research Center autopsy cohort.
Alzheimers Dement. 2022 Mar 10. doi: 10.1002/alz.12639.
PubMed Abstract available

GATZ M, Mack WJ, Chui HC, Law EM, et al
Prevalence of dementia and mild cognitive impairment in indigenous Bolivian forager-horticulturalists.
Alzheimers Dement. 2022;19:44-55.
PubMed Abstract available

BREITNER JCS, Dodge HH, Khachaturian ZS, Khachaturian AS, et al
"Exceptions that prove the rule"-Why have clinical trials failed to show efficacy of risk factor interventions suggested by observational studies of the dementia-Alzheimer's disease syndrome?
Alzheimers Dement. 2022 Mar 4. doi: 10.1002/alz.12633.
PubMed

Alzheimer's Association welcomes new Medical and Scientific Advisory Group members.
Alzheimers Dement. 2022 Mar 4. doi: 10.1002/alz.12621.
PubMed

O'BRYANT SE, Petersen M, Hall J, Johnson LA, et al
Medical comorbidities and ethnicity impact plasma Alzheimer's disease biomarkers: Important considerations for clinical trials and practice.
Alzheimers Dement. 2022 Mar 2. doi: 10.1002/alz.12647.
PubMed Abstract available

CONNOLLY K, Lehoux M, O'Rourke R, Assetta B, et al
Potential role of chitinase-3-like protein 1 (CHI3L1/YKL-40) in neurodegeneration and Alzheimer's disease.
Alzheimers Dement. 2022 Mar 2. doi: 10.1002/alz.12612.
PubMed Abstract available

STOCKER H, Beyer L, Perna L, Rujescu D, et al
Association of plasma biomarkers, p-tau181, glial fibrillary acidic protein, and neurofilament light, with intermediate and long-term clinical Alzheimer's disease risk: Results from a prospective cohort followed over 17 years.
Alzheimers Dement. 2022 Mar 2. doi: 10.1002/alz.12614.
PubMed Abstract available

CUMMINGS J, Salloway S
Aducanumab: Appropriate use recommendations.
Alzheimers Dement. 2022;18:531-533.
PubMed

PETERSON A, Clapp J, Largent EA, Harkins K, et al
What is paradoxical lucidity? The answer begins with its definition.
Alzheimers Dement. 2022;18:513-521.
PubMed Abstract available

BARIL AA, Beiser AS, Sanchez E, Mysliwiec V, et al
Insomnia symptom severity and cognitive performance: Moderating role of APOE genotype.
Alzheimers Dement. 2022;18:408-421.
PubMed Abstract available

February 2022

GIETL AF, Frisoni GB
Early termination of pivotal trials in Alzheimer's disease-Preserving optimal value for participants and science.
Alzheimers Dement. 2022 Feb 27. doi: 10.1002/alz.12605.
PubMed Abstract available

KETCHUM FB, Chin NA, Grill J, Gleason CE, et al
Moving beyond disclosure: Stages of care in preclinical Alzheimer's disease biomarker testing.
Alzheimers Dement. 2022 Feb 25. doi: 10.1002/alz.12620.
PubMed Abstract available

ASHFORD MT, Raman R, Miller G, Donohue MC, et al
Screening and enrollment of underrepresented ethnocultural and educational populations in the Alzheimer's Disease Neuroimaging Initiative (ADNI).
Alzheimers Dement. 2022 Feb 25. doi: 10.1002/alz.12640.
PubMed Abstract available

ZETTERBERG H
Biofluid-based biomarkers for Alzheimer's disease-related pathologies: An update and synthesis of the literature.
Alzheimers Dement. 2022 Feb 25. doi: 10.1002/alz.12618.
PubMed Abstract available

XIONG C, Luo J, Schindler SE, Fagan AM, et al
Racial differences in longitudinal Alzheimer's disease biomarkers among cognitively normal adults.
Alzheimers Dement. 2022 Feb 25. doi: 10.1002/alz.12608.
PubMed Abstract available

MONI F, Petersen ME, Zhang F, Lao PJ, et al
Probing the proteome to explore potential correlates of increased Alzheimer's-related cerebrovascular disease in adults with Down syndrome.
Alzheimers Dement. 2022 Feb 24. doi: 10.1002/alz.12627.
PubMed Abstract available

LEVIN J, Voglein J, Quiroz YT, Bateman RJ, et al
Testing the amyloid cascade hypothesis: Prevention trials in autosomal dominant Alzheimer disease.
Alzheimers Dement. 2022 Feb 24. doi: 10.1002/alz.12624.
PubMed Abstract available

QUIROZ YT, Solis M, Aranda MP, Arbaje AI, et al
Addressing the disparities in dementia risk, early detection and care in Latino populations: Highlights from the second Latinos & Alzheimer's Symposium.
Alzheimers Dement. 2022 Feb 24. doi: 10.1002/alz.12589.
PubMed Abstract available

SEXTON C, Solis M, Aharon-Peretz J, Alexopoulos P, et al
Alzheimer's disease research progress in the Mediterranean region: The Alzheimer's Association International Conference Satellite Symposium.
Alzheimers Dement. 2022 Feb 20. doi: 10.1002/alz.12588.
PubMed Abstract available

MECCA AP, O'Dell RS, Sharp ES, Banks ER, et al
Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [(11) C]UCB-J.
Alzheimers Dement. 2022 Feb 17. doi: 10.1002/alz.12582.
PubMed Abstract available

SUCHY-DICEY A, Howard B, Longstreth WT Jr, Reiman EM, et al
APOE genotype, hippocampus, and cognitive markers of Alzheimer's disease in American Indians: Data from the Strong Heart Study.
Alzheimers Dement. 2022 Feb 10. doi: 10.1002/alz.12573.
PubMed Abstract available

KRELL-ROESCH J, Rakusa M, Syrjanen JA, van Harten AC, et al
Association between CSF biomarkers of Alzheimer's disease and neuropsychiatric symptoms: Mayo Clinic Study of Aging.
Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12557.
PubMed Abstract available

CLAES C, England WE, Danhash EP, Kiani Shabestari S, et al
The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model.
Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12577.
PubMed Abstract available

HU WT
Reporting and social construction of race in Alzheimer's disease clinical trials.
Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12609.
PubMed

ASTILLERO-LOPEZ V, Gonzalez-Rodriguez M, Villar-Conde S, Flores-Cuadrado A, et al
Neurodegeneration and astrogliosis in the entorhinal cortex in Alzheimer's disease: Stereological layer-specific assessment and proteomic analysis.
Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12580.
PubMed Abstract available

FLACH M, Leu C, Martinisi A, Skachokova Z, et al
Trans-seeding of Alzheimer-related tau protein by a yeast prion.
Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12581.
PubMed Abstract available

PRADOS MJ, Liu Y, Jun H, Lam J, et al
Projecting the long-term societal value of a disease-modifying treatment for Alzheimer's disease in the United States.
Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12578.
PubMed Abstract available

BABULAL GM, Franzen S, Abner EL, Smith JE, et al
Diversity in Alzheimer's disease drug trials: Reflections on reporting and social construction of race.
Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12611.
PubMed

JUN GR, You Y, Zhu C, Meng G, et al
Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE varepsilon2 for Alzheimer's disease.
Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12607.
PubMed Abstract available

VARDARAJAN BN, Reyes-Dumeyer D, Piriz AL, Lantigua RA, et al
Progranulin mutations in clinical and neuropathological Alzheimer's disease.
Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12567.
PubMed Abstract available

REIKEN S, Sittenfeld L, Dridi H, Liu Y, et al
Alzheimer's-like signaling in brains of COVID-19 patients.
Alzheimers Dement. 2022 Feb 3. doi: 10.1002/alz.12558.
PubMed Abstract available

RUTHIRAKUHAN M, Ismail Z, Herrmann N, Gallagher D, et al
Mild behavioral impairment is associated with progression to Alzheimer's disease: A clinicopathological study.
Alzheimers Dement. 2022 Feb 1. doi: 10.1002/alz.12519.
PubMed Abstract available

REIMAN EM, Mattke S, Kordower JH, Khachaturian ZS, et al
Developing a pathway to support the appropriate, affordable, and widespread use of effective Alzheimer's prevention drugs.
Alzheimers Dement. 2022 Feb 1. doi: 10.1002/alz.12533.
PubMed

Applications being accepted for the Alzheimer's Association Interdisciplinary Summer Research Institute.
Alzheimers Dement. 2022 Feb 1. doi: 10.1002/alz.12585.
PubMed

VILA-CASTELAR C, Tariot PN, Sink KM, Clayton D, et al
Sex differences in cognitive resilience in preclinical autosomal-dominant Alzheimer's disease carriers and non-carriers: Baseline findings from the API ADAD Colombia Trial.
Alzheimers Dement. 2022 Feb 1. doi: 10.1002/alz.12552.
PubMed Abstract available

WAGNER M, Wilson RS, Leurgans SE, Boyle PA, et al
Quantifying longitudinal cognitive resilience to Alzheimer's disease and other neuropathologies.
Alzheimers Dement. 2022 Feb 1. doi: 10.1002/alz.12576.
PubMed Abstract available

ERATNE D, Loi SM, Li QX, Stehmann C, et al
Cerebrospinal fluid neurofilament light chain differentiates primary psychiatric disorders from rapidly progressive, Alzheimer's disease and frontotemporal disorders in clinical settings.
Alzheimers Dement. 2022 Feb 1. doi: 10.1002/alz.12549.
PubMed Abstract available

O'BRYANT S, Petersen M, Hall J, Johnson L, et al
Characterizing plasma NfL in a community-dwelling multi-ethnic cohort: Results from the HABLE study.
Alzheimers Dement. 2022;18:240-250.
PubMed Abstract available

NAUEN DW, Troncoso JC
Amyloid-beta is present in human lymph nodes and greatly enriched in those of the cervical region.
Alzheimers Dement. 2022;18:205-210.
PubMed Abstract available

KREISL WC, Lao PJ, Johnson A, Tomljanovic Z, et al
Patterns of tau pathology identified with (18) F-MK-6240 PET imaging.
Alzheimers Dement. 2022;18:272-282.
PubMed Abstract available

SCHMUTTE T, Olfson M, Maust DT, Xie M, et al
Suicide risk in first year after dementia diagnosis in older adults.
Alzheimers Dement. 2022;18:262-271.
PubMed Abstract available

January 2022

CALDWELL AB, Liu Q, Zhang C, Schroth GP, et al
Endotype reversal as a novel strategy for screening drugs targeting familial Alzheimer's disease.
Alzheimers Dement. 2022 Jan 27. doi: 10.1002/alz.12553.
PubMed Abstract available

WANG T, Huynh K, Giles C, Mellett NA, et al
APOE epsilon2 resilience for Alzheimer's disease is mediated by plasma lipid species: Analysis of three independent cohort studies.
Alzheimers Dement. 2022 Jan 25. doi: 10.1002/alz.12538.
PubMed Abstract available

JORDA-SIQUIER T, Petrel M, Kouskoff V, Smailovic U, et al
APP accumulates with presynaptic proteins around amyloid plaques: A role for presynaptic mechanisms in Alzheimer's disease?
Alzheimers Dement. 2022 Jan 25. doi: 10.1002/alz.12546.
PubMed Abstract available

FRONTERA JA, Boutajangout A, Masurkar AV, Betensky RA, et al
Comparison of serum neurodegenerative biomarkers among hospitalized COVID-19 patients versus non-COVID subjects with normal cognition, mild cognitive impairment, or Alzheimer's dementia.
Alzheimers Dement. 2022 Jan 13. doi: 10.1002/alz.12556.
PubMed Abstract available

YAO J, Liu Y, Sun B, Zhan X, et al
Increased RyR2 open probability induces neuronal hyperactivity and memory loss with or without Alzheimer's disease-causing gene mutations.
Alzheimers Dement. 2022 Jan 5. doi: 10.1002/alz.12543.
PubMed Abstract available

NAZARIAN A, Loika Y, He L, Culminskaya I, et al
Genome-wide analysis identified abundant genetic modulators of contributions of the apolipoprotein E alleles to Alzheimer's disease risk.
Alzheimers Dement. 2022 Jan 3. doi: 10.1002/alz.12540.
PubMed Abstract available

REYES-DUMEYER D, Faber K, Vardarajan B, Goate A, et al
The National Institute on Aging Late-Onset Alzheimer's Disease Family Based Study: A resource for genetic discovery.
Alzheimers Dement. 2022 Jan 3. doi: 10.1002/alz.12514.
PubMed Abstract available

QIU S, Hu Y, Cheng L
BIN1 rs744373 located in enhancers of brain tissues upregulates BIN1 mRNA expression, thereby leading to Alzheimer's disease.
Alzheimers Dement. 2022 Jan 3. doi: 10.1002/alz.12548.
PubMed

ZAMOLODCHIKOV D, Duffield M, Macdonald LE, Alessandri-Haber N, et al
Accumulation of high molecular weight kininogen in the brains of Alzheimer's disease patients may affect microglial function by altering phagocytosis and lysosomal cathepsin activity.
Alzheimers Dement. 2022 Jan 3. doi: 10.1002/alz.12531.
PubMed Abstract available

Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring announces new editor-in-chief for open access, peer reviewed journal.
Alzheimers Dement. 2022 Jan 3. doi: 10.1002/alz.12517.
PubMed

KETCHUM FB
Solomon Carter Fuller: Alzheimer's contemporary and American pioneer.
Alzheimers Dement. 2022 Jan 3. doi: 10.1002/alz.12551.
PubMed

JAKEL L, De Kort AM, Klijn CJM, Schreuder FHBM, et al
Prevalence of cerebral amyloid angiopathy: A systematic review and meta-analysis.
Alzheimers Dement. 2022;18:10-28.
PubMed Abstract available

ZHAO Y, Kuca K, Wu W, Wang X, et al
Hypothesis: JNK signaling is a therapeutic target of neurodegenerative diseases.
Alzheimers Dement. 2022;18:152-158.
PubMed Abstract available

BUTT OH, Meeker KL, Wisch JK, Schindler SE, et al
Network dysfunction in cognitively normal APOE epsilon4 carriers is related to subclinical tau.
Alzheimers Dement. 2022;18:116-126.
PubMed Abstract available

VOGT NM, Hunt JFV, Adluru N, Ma Y, et al
Interaction of amyloid and tau on cortical microstructure in cognitively unimpaired adults.
Alzheimers Dement. 2022;18:65-76.
PubMed Abstract available

December 2021

DELABY C, Teunissen CE, Blennow K, Alcolea D, et al
Clinical reporting following the quantification of cerebrospinal fluid biomarkers in Alzheimer's disease: An international overview.
Alzheimers Dement. 2021 Dec 22. doi: 10.1002/alz.12545.
PubMed Abstract available

MING C, Wang M, Wang Q, Neff R, et al
Whole genome sequencing-based copy number variations reveal novel pathways and targets in Alzheimer's disease.
Alzheimers Dement. 2021 Dec 17. doi: 10.1002/alz.12507.
PubMed Abstract available

HAWKINSON TR, Clarke HA, Young LEA, Conroy LR, et al
In situ spatial glycomic imaging of mouse and human Alzheimer's disease brains.
Alzheimers Dement. 2021 Dec 15. doi: 10.1002/alz.12523.
PubMed Abstract available

LIM U, Wang S, Park SY, Bogumil D, et al
Risk of Alzheimer's disease and related dementia by sex and race/ethnicity: The Multiethnic Cohort Study.
Alzheimers Dement. 2021 Dec 9. doi: 10.1002/alz.12528.
PubMed Abstract available

GORDON MN, Heneka MT, Le Page LM, Limberger C, et al
Impact of COVID-19 on the Onset and Progression of Alzheimer's Disease and Related Dementias: A Roadmap for Future Research.
Alzheimers Dement. 2021 Dec 7. doi: 10.1002/alz.12488.
PubMed Abstract available

DE KORT AM, Kuiperij HB, Kersten I, Versleijen AAM, et al
Normal cerebrospinal fluid concentrations of PDGFRbeta in patients with cerebral amyloid angiopathy and Alzheimer's disease.
Alzheimers Dement. 2021 Dec 7. doi: 10.1002/alz.12506.
PubMed Abstract available

SILVERMAN W, Krinsky-McHale SJ, Zigman WB, Schupf N, et al
Adults with Down syndrome in randomized clinical trials targeting prevention of Alzheimer's disease.
Alzheimers Dement. 2021 Dec 7. doi: 10.1002/alz.12520.
PubMed Abstract available

SAROJA SR, Sharma A, Hof PR, Pereira AC, et al
Differential expression of tau species and the association with cognitive decline and synaptic loss in Alzheimer's disease.
Alzheimers Dement. 2021 Dec 7. doi: 10.1002/alz.12518.
PubMed Abstract available

GLEASON CE, Zuelsdorff M, Gooding DC, Kind AJH, et al
Alzheimer's disease biomarkers in Black and non-Hispanic White cohorts: A contextualized review of the evidence.
Alzheimers Dement. 2021 Dec 6. doi: 10.1002/alz.12511.
PubMed Abstract available

HAEGER A, Bottlaender M, Lagarde J, Porciuncula Baptista R, et al
What can 7T sodium MRI tell us about cellular energy depletion and neurotransmission in Alzheimer's disease?
Alzheimers Dement. 2021 Dec 2. doi: 10.1002/alz.12501.
PubMed Abstract available

AAIC 2021: The promise of Alzheimer's research.
Alzheimers Dement. 2021 Dec 2. doi: 10.1002/alz.12500.
PubMed

FRANK B, Ally M, Brekke B, Zetterberg H, et al
Plasma p-tau181 shows stronger network association to Alzheimer's disease dementia than neurofilament light and total tau.
Alzheimers Dement. 2021 Dec 2. doi: 10.1002/alz.12508.
PubMed Abstract available

STATHAS S, Alvarez VE, Xia W, Nicks R, et al
Tau phosphorylation sites serine202 and serine396 are differently altered in chronic traumatic encephalopathy and Alzheimer's disease.
Alzheimers Dement. 2021 Dec 2. doi: 10.1002/alz.12502.
PubMed Abstract available

BUCKLES VD, Xiong C, Bateman RJ, Hassenstab J, et al
Different rates of cognitive decline in autosomal dominant and late-onset Alzheimer disease.
Alzheimers Dement. 2021 Dec 2. doi: 10.1002/alz.12505.
PubMed Abstract available

STRINGER C, Smithroat N, Samus QM, Johnston D, et al
From research to realization: How a Texas health plan implemented an academic model of care for Alzheimer's disease.
Alzheimers Dement. 2021;17 Suppl 8:e054058.
PubMed Abstract available

MENENGIC KN, Yeldan I, Cinar N, Sahiner TA, et al
Effectiveness of home-based telerehabilitation in mild to moderate Alzheimer's disease: A randomised controlled study.
Alzheimers Dement. 2021;17 Suppl 8:e053406.
PubMed Abstract available

ASCHETTINO LA, Labyak CA, Sealey-Potts C
Nutritional treatments for Alzheimer's disease: A narrative review.
Alzheimers Dement. 2021;17 Suppl 8:e053172.
PubMed Abstract available

LEE JH, Kim DY, Kim MG, Kang H, et al
Preventing cognitive decline in older adults with mild cognitive impairment using integrated Korean and Western treatments: Initial results.
Alzheimers Dement. 2021;17 Suppl 8:e052545.
PubMed Abstract available

GELDMACHER DS, Christopher R, Anderson M, Bero AW, et al
Development of a site readiness framework to improve health system preparedness for potential new Alzheimer's disease therapies.
Alzheimers Dement. 2021;17 Suppl 8:e057672.
PubMed Abstract available

KEELY AJ
The first female engineer at General Motor's descent into Alzheimer's with sundowners: A daughter's scholarly research and case study as caregiver.
Alzheimers Dement. 2021;17 Suppl 8:e050143.
PubMed Abstract available

FLATT JD, Pollock K, Lee R, Song Y, et al
Feasibility of the Savvy Caregiver program for care providers of LGBTQ adults living with Alzheimer's disease and related dementias.
Alzheimers Dement. 2021;17 Suppl 8:e055633.
PubMed Abstract available

MILLER DR, Jasuja G, Davila HW, Palnati M, et al
Care processes related to clinical detection of Alzheimer's disease in the U.S. Veterans Affairs Health Care System.
Alzheimers Dement. 2021;17 Suppl 8:e054149.
PubMed Abstract available

MAKSIMOVICH IV
Stimulation of cerebral angiogenesis and neurogenesis with transcatheter intracerebral laser photobiomodulation therapy during dementia in patients with Alzheimer's and Binswanger's disease.
Alzheimers Dement. 2021;17 Suppl 8:e054945.
PubMed Abstract available

GONZALEZ A, Camila C, Maccioni RB
Alzheimer's disease: A potential diabetes type 3.
Alzheimers Dement. 2021;17 Suppl 2:e058533.
PubMed Abstract available

MOYLAN C, Cao TV, Huynh QS, Pratap A, et al
Exercise-Induced Alterations in TrkB expression in the 5XFAD Mouse Model of Alzheimer's Disease.
Alzheimers Dement. 2021;17 Suppl 2:e058733.
PubMed Abstract available

GAITAN JM, Dubal DB, Okonkwo OC
Circulating klotho is elevated in cerebrospinal fluid, but not serum, among KLOTHO KL-VS allele carriers at risk for Alzheimer's disease.
Alzheimers Dement. 2021;17 Suppl 2:e058612.
PubMed Abstract available

COULON A, Mendes T, Kilinc D, Dumont J, et al
High-content screening of Alzheimer's disease genetic risk factors based on synaptic density analysis.
Alzheimers Dement. 2021;17 Suppl 2:e058660.
PubMed Abstract available

TSAI AP, Lin PB, Dong C, Moutinho M, et al
Impact of PLCG2 expression on Microglial Biology and Disease Pathogenesis in Alzheimer's Disease.
Alzheimers Dement. 2021;17 Suppl 2:e058740.
PubMed Abstract available

HUANG CW, Hart GW
Decreased O-GlcNAcylation and mitochondrial dysfunction are involving in low glucose induced Alzheimer's disease-like phenotype in induced pluripotent stem cell-derived neurons.
Alzheimers Dement. 2021;17 Suppl 2:e058620.
PubMed Abstract available

BRACH TL, Gaitan JM, Okonkwo OC
Effect of Aerobic Exercise Training on Mood and Cognition in Adults at Risk for Alzheimer's Disease.
Alzheimers Dement. 2021;17 Suppl 2:e058523.
PubMed Abstract available

LIN PB, Tsai AP, Nho K, Lamb BT, et al
INPP5D regulates the amyloid pathology in Alzheimer's disease.
Alzheimers Dement. 2021;17 Suppl 2:e058724.
PubMed Abstract available

KUMAR A, Doran E, Martini AC, Head E, et al
CAA and related co-morbidities in Down syndrome and Alzheimer disease.
Alzheimers Dement. 2021;17 Suppl 2:e058726.
PubMed Abstract available

TEMITOPE SR
The role of lycopene on the hippocampus of rat model of lipopolysaccharide-induced Alzheimer's disease.
Alzheimers Dement. 2021;17 Suppl 2:e058528.
PubMed Abstract available

YEATES C, Sarkar A, Deshpande P, Kango-Singh M, et al
A Two-Clone approach to study signaling interactions among neuronal cells in a pre-clinical Alzheimer's Disease model.
Alzheimers Dement. 2021;17 Suppl 2:e058690.
PubMed Abstract available

GOMEZ J JR, Villegas-Lanau CA, Mesa A Sr
Colocalization of the beta amyloid peptide with bacteria in postmortem brain tissue of patients with familial Alzheimer's disease.
Alzheimers Dement. 2021;17 Suppl 2:e058692.
PubMed Abstract available

SUNG K, Yang F, Noble W, Jimenez-Sanchez M, et al
Investigating the non-cell autonomous role of glial chaperones in Alzheimer's disease.
Alzheimers Dement. 2021;17 Suppl 2:e058572.
PubMed Abstract available

GOMEZ J JR, Villegas-Lanau CA, Mesa A Sr
Human Herpesvirus detection and identification in postmortem brain tissue of patients with Alzheimer's disease.
Alzheimers Dement. 2021;17 Suppl 2:e058693.
PubMed Abstract available

SCHRAUBEN M, Smith AR, Washer S, Dempster E, et al
Investigating epigenetic loci implicated in Alzheimer's disease via the CRISPR-Cas9 system.
Alzheimers Dement. 2021;17 Suppl 2:e058573.
PubMed Abstract available

TALIYAN R, Kakoty V, Kc S, Kumari S, et al
Fibroblast Growth Factor 21 and Autophagy Modulation Ameliorates Amyloid beta-Induced Alzheimer Disease Pathology in Rats.
Alzheimers Dement. 2021;17 Suppl 2:e058695.
PubMed Abstract available

YANG F, Sung K, Sanchez MJ
Investigating the secretion of small heat shock proteins in reactive astrocytes in Alzheimer's disease.
Alzheimers Dement. 2021;17 Suppl 2:e058498.
PubMed Abstract available

ROSENE MJ, Hsu S, Martinez R, Norton J, et al
Defining the role of PLD3 in Alzheimer's disease pathology.
Alzheimers Dement. 2021;17 Suppl 2:e058730.
PubMed Abstract available

TREMBLAY JP, Tremblay G, Guyon A, Joel R, et al
Insertion of the Icelandic mutation (A673T) in the APP gene using the CRISPR/Cas9 base editing and Prime editing technologies, a preventive treatment for Alzheimer?
Alzheimers Dement. 2021;17 Suppl 2:e058710.
PubMed Abstract available

CHEN J, Samoylova NG, Cummings MG
TOMM40, a risk gene for Alzheimer's disease, is upregulated during proinflammatory response.
Alzheimers Dement. 2021;17 Suppl 2:e058711.
PubMed Abstract available

MCARDLE CJ, Niere F, Uneri A, Raab-Graham KF, et al
Alterations in dendritic GABAB receptor expression in an Alzheimer's disease mouse model.
Alzheimers Dement. 2021;17 Suppl 2:e058557.
PubMed Abstract available

DESHPANDE P, Chen CY, Yeates C, Chen CH, et al
miR-277 targets hid to ameliorate Abeta42-mediated neurodegeneration in Drosophila eye model of Alzheimer's Disease.
Alzheimers Dement. 2021;17 Suppl 2:e058678.
PubMed Abstract available

ZHAO P, Mangleburg CG, Al-Ramahi I, Botas J, et al
Systems genetic dissection of Alzheimer's disease brain gene expression networks.
Alzheimers Dement. 2021;17 Suppl 2:e058716.
PubMed Abstract available

MUMFORD P, Noy S, Tybulewicz VL, Fisher E, et al
Preclinical modelling in the mouse of altered neuroinflammation in Alzheimer's disease - Down syndrome.
Alzheimers Dement. 2021;17 Suppl 2:e058441.
PubMed Abstract available

TIPTON AE, George J, Ratner M, Farb D, et al
Data from single nuclei RNA-sequencing reveals a prodromal gene network response in excitatory neurons of a humanized rat Alzheimer's disease model.
Alzheimers Dement. 2021;17 Suppl 2:e058589.
PubMed Abstract available

TAYLOR AL, Davis DE Jr, Codreanu SG, Harrison FE, et al
Targeted and untargeted mass spectrometry reveals impact of high fat diet on peripheral amino acid regulation in a mouse model of Alzheimer's disease.
Alzheimers Dement. 2021;17 Suppl 2:e058428.
PubMed Abstract available

ROSOLEN SA
Exercise-induced metabolic changes in astrocytes in the 5xFAD mouse model of Alzheimer's Disease.
Alzheimers Dement. 2021;17 Suppl 2:e058627.
PubMed Abstract available

SRIVASTAV A, Mohideen SS
Intestinal microbial dysbiosis induced tau accumulation establishes a gut-brain correlation for pathology Alzheimer's disease in Drosophila melanogaster.
Alzheimers Dement. 2021;17 Suppl 2:e058708.
PubMed Abstract available

HERSH SW, You Y, Aslebagh R, Shaffer SA, et al
Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells.
Alzheimers Dement. 2021;17 Suppl 2:e058592.
PubMed Abstract available

PRATER KE, Green KJ, Chiou KL, Smith CL, et al
Microglia subtype transcriptomes differ between Alzheimer Disease and control human postmortem brain samples.
Alzheimers Dement. 2021;17 Suppl 2:e058474.
PubMed Abstract available

CZAPLICKI AM, Gaitan JM, Bendlin BB, Johnson SC, et al
The Interaction between Ventricle to Brain Ratio and Serum Klotho on Cognition in Older Adults at Risk for Alzheimer's Disease.
Alzheimers Dement. 2021;17 Suppl 12:e058632.
PubMed Abstract available

BABATOPE EY, Acosta-Franco JA, Garcia-Vazquez MS, Ramirez-Acosta AA, et al
Applying a deep learning approach focusing on spatiotemporal features in early diagnosis of Alzheimer's disease.
Alzheimers Dement. 2021;17 Suppl 12:e058635.
PubMed Abstract available

MCINTYRE CC, Okonkwo OC, Gaitan JM, Bendlin BB, et al
Effect of insulin resistance on the association between cardiorespiratory fitness and cognition in adults at risk for Alzheimer's disease.
Alzheimers Dement. 2021;17 Suppl 12:e058683.
PubMed Abstract available

WANG RP, Leung WK, Goto T, Ho JY, et al
IL-1 beta and TNF-alpha play an essential role in modulating the risk of both periodontitis and Alzheimer's disease.
Alzheimers Dement. 2021;17 Suppl 12:e058464.
PubMed Abstract available

MEMUDU AE, Waziri RJ
An investigative study to demonstrate the link between combined intake of marijuana and codeine in Alzheimer's disease pathology.
Alzheimers Dement. 2021;17 Suppl 12:e058465.
PubMed Abstract available

RISHITHA N, Muthuraman A
Therapeutic investigation of alpha napthoflavone in the intracerebroventricular injection of L-cysteine induced vascular dementia in rats.
Alzheimers Dement. 2021;17 Suppl 12:e058344.
PubMed Abstract available

ABDULKADIR TS, Isa AS, Dawud FA, Ayo JO, et al
Effect of taurine and camel milk on amyloid beta peptide concentration and oxidative stress changes in aluminium chloride-induced Alzheimer's disease rats.
Alzheimers Dement. 2021;17 Suppl 12:e058642.
PubMed Abstract available

OKHUEVBIE DO, Awolaja S, Balogun Z
Evaluation of the effect of Donepezil hydrochloride on Ethanol-induced hippocampal damage.
Alzheimers Dement. 2021;17 Suppl 12:e058353.
PubMed Abstract available

K C S, Kakoty VK, Taliyan R
Development and Validation of PEG-PCL Based Nanoformulation of Rosiglitazone and Evaluation of its Brain Selectivity in Mice Model of Alzheimer's disease.
Alzheimers Dement. 2021;17 Suppl 12:e058674.
PubMed Abstract available

TORT-MERINO A, Tarnanas I, Bugler M, Harms R, et al
ALTOIDA-iADL for the diagnosis of Mild Cognitive Impairment and early Alzheimer's disease.
Alzheimers Dement. 2021;17 Suppl 12:e057982.
PubMed Abstract available

ROWE EM, Louadi S, Koch E, Kuhlmann N, et al
A Month in Neurodegenerative Disease Research (AMiNDR): The evolution of an open-access podcast series for Alzheimer's researchers.
Alzheimers Dement. 2021;17 Suppl 11:e053287.
PubMed Abstract available

YUAN F, Lopez RP, Crane M, Montgomery A, et al
Feasibility and acceptance of robotic care of Alzheimer's disease and related dementia.
Alzheimers Dement. 2021;17 Suppl 11:e052585.
PubMed Abstract available

KUHNEL L, Bouteloup V, Lespinasse J, Chene G, et al
Personalized prediction of progression in pre-dementia patients based on individual biomarker profile: A development and validation study.
Alzheimers Dement. 2021;17:1938-1949.
PubMed Abstract available

GOLD BT, Shao X, Sudduth TL, Jicha GA, et al
Water exchange rate across the blood-brain barrier is associated with CSF amyloid-beta 42 in healthy older adults.
Alzheimers Dement. 2021;17:2020-2029.
PubMed Abstract available

XU Y, Chen Z, Wey HY, Liang Y, et al
Molecular imaging of NAD(+) -dependent deacetylase SIRT1 in the brain.
Alzheimers Dement. 2021;17:1988-1997.
PubMed Abstract available

November 2021

VERBERK IMW, Misdorp EO, Koelewijn J, Ball AJ, et al
Characterization of pre-analytical sample handling effects on a panel of Alzheimer's disease-related blood-based biomarkers: Results from the Standardization of Alzheimer's Blood Biomarkers (SABB) working group.
Alzheimers Dement. 2021 Nov 29. doi: 10.1002/alz.12510.
PubMed Abstract available

MURCHISON AG
Hypothesis: Modulation of microglial phenotype in Alzheimer's disease drives neurodegeneration.
Alzheimers Dement. 2021 Nov 17. doi: 10.1002/alz.12503.
PubMed Abstract available

JIA L, Yang J, Zhu M, Pang Y, et al
A metabolite panel that differentiates Alzheimer's disease from other dementia types.
Alzheimers Dement. 2021 Nov 17. doi: 10.1002/alz.12484.
PubMed Abstract available

WEINTRAUB S, Karpouzian-Rogers T, Peipert JD, Nowinski C, et al
ARMADA: Assessing reliable measurement in Alzheimer's disease and cognitive aging project methods.
Alzheimers Dement. 2021 Nov 17. doi: 10.1002/alz.12497.
PubMed Abstract available

JUTKOWITZ E, Halladay C, Tsai J, Hooshyar D, et al
Prevalence of Alzheimer's disease and related dementias among veterans experiencing housing insecurity.
Alzheimers Dement. 2021 Nov 10. doi: 10.1002/alz.12476.
PubMed Abstract available

HORGUSLUOGLU E, Neff R, Song WM, Wang M, et al
Integrative metabolomics-genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease.
Alzheimers Dement. 2021 Nov 10. doi: 10.1002/alz.12468.
PubMed Abstract available

BOADA M, Lopez OL, Olazaran J, Nunez L, et al
Neuropsychological, neuropsychiatric, and quality-of-life assessments in Alzheimer's disease patients treated with plasma exchange with albumin replacement from the randomized AMBAR study.
Alzheimers Dement. 2021 Nov 2. doi: 10.1002/alz.12477.
PubMed Abstract available

EZZATI A, Abdulkadir A, Jack CR Jr, Thompson PM, et al
Predictive value of ATN biomarker profiles in estimating disease progression in Alzheimer's disease dementia.
Alzheimers Dement. 2021;17:1855-1867.
PubMed Abstract available

TAHIRA AC, Verjovski-Almeida S, Ferreira ST
Dementia is an age-independent risk factor for severity and death in COVID-19 inpatients.
Alzheimers Dement. 2021;17:1818-1831.
PubMed Abstract available

October 2021

TOSUN D, Demir Z, Veitch DP, Weintraub D, et al
Contribution of Alzheimer's biomarkers and risk factors to cognitive impairment and decline across the Alzheimer's disease continuum.
Alzheimers Dement. 2021 Oct 14. doi: 10.1002/alz.12480.
PubMed Abstract available

MEYERS EA, Amouyel P, Bovenkamp DE, Carrillo MC, et al
Commentary: Global Alzheimer's disease and Alzheimer's disease related dementia research funding organizations support and engage the research community throughout the COVID-19 pandemic.
Alzheimers Dement. 2021 Oct 1. doi: 10.1002/alz.12472.
PubMed Abstract available

Alzheimer's Disease Interventions: Implications of therapeutic promises amidst questions and doubts about clinically meaningful outcomes.
Alzheimers Dement. 2021;17:1591-1594.
PubMed

DE MAULEON A, Ismail Z, Rosenberg P, Miller D, et al
Agitation in Alzheimer's disease: Novel outcome measures reflecting the International Psychogeriatric Association (IPA) agitation criteria.
Alzheimers Dement. 2021;17:1687-1697.
PubMed Abstract available

DAMOTTE V, van der Lee SJ, Chouraki V, Grenier-Boley B, et al
Plasma amyloid beta levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants.
Alzheimers Dement. 2021;17:1663-1674.
PubMed Abstract available

BANGEN KJ, Thomas KR, Weigand AJ, Edmonds EC, et al
Elevated plasma neurofilament light predicts a faster rate of cognitive decline over 5 years in participants with objectively-defined subtle cognitive decline and MCI.
Alzheimers Dement. 2021;17:1756-1762.
PubMed Abstract available

MEZ J, Alosco ML, Daneshvar DH, Saltiel N, et al
Validity of the 2014 traumatic encephalopathy syndrome criteria for CTE pathology.
Alzheimers Dement. 2021;17:1709-1724.
PubMed Abstract available

GALVIN JE, Chrisphonte S, Cohen I, Greenfield KK, et al
Characterization of dementia with Lewy bodies (DLB) and mild cognitive impairment using the Lewy body dementia module (LBD-MOD).
Alzheimers Dement. 2021;17:1675-1686.
PubMed Abstract available

YANG C, Li X, Zhang J, Chen Y, et al
Early prevention of cognitive impairment in the community population: The Beijing Aging Brain Rejuvenation Initiative.
Alzheimers Dement. 2021;17:1610-1618.
PubMed Abstract available

September 2021

FRANZEN S, Smith JE, van den Berg E, Rivera Mindt M, et al
Diversity in Alzheimer's disease drug trials: The importance of eligibility criteria.
Alzheimers Dement. 2021 Sep 30. doi: 10.1002/alz.12433.
PubMed Abstract available

PICARD C, Nilsson N, Labonte A, Auld D, et al
Apolipoprotein B is a novel marker for early tau pathology in Alzheimer's disease.
Alzheimers Dement. 2021 Sep 29. doi: 10.1002/alz.12442.
PubMed Abstract available

JICHA GA, Abner EL, Arnold SE, Carrillo MC, et al
Committee on High-quality Alzheimer's Disease Studies (CHADS) consensus report.
Alzheimers Dement. 2021 Sep 29. doi: 10.1002/alz.12461.
PubMed Abstract available

CUMMINGS JL, Goldman DP, Simmons-Stern NR, Ponton E, et al
The costs of developing treatments for Alzheimer's disease: A retrospective exploration.
Alzheimers Dement. 2021 Sep 28. doi: 10.1002/alz.12450.
PubMed Abstract available

VEITCH DP, Weiner MW, Aisen PS, Beckett LA, et al
Using the Alzheimer's Disease Neuroimaging Initiative to improve early detection, diagnosis, and treatment of Alzheimer's disease.
Alzheimers Dement. 2021 Sep 28. doi: 10.1002/alz.12422.
PubMed Abstract available

WANG C, Wang Z, Xie B, Shi X, et al
Binaural processing deficit and cognitive impairment in Alzheimer's disease.
Alzheimers Dement. 2021 Sep 27. doi: 10.1002/alz.12464.
PubMed Abstract available

MATTKE S, Hanson M
Expected wait times for access to a disease-modifying Alzheimer's treatment in the United States.
Alzheimers Dement. 2021 Sep 27. doi: 10.1002/alz.12470.
PubMed Abstract available

PHILLIPS JS, Nitchie FJ 4th, Da Re F, Olm CA, et al
Rates of longitudinal change in (18) F-flortaucipir PET vary by brain region, cognitive impairment, and age in atypical Alzheimer's disease.
Alzheimers Dement. 2021 Sep 13. doi: 10.1002/alz.12456.
PubMed Abstract available

ZHANG L, Du Rietz E, Kuja-Halkola R, Dobrosavljevic M, et al
Attention-deficit/hyperactivity disorder and Alzheimer's disease and any dementia: A multi-generation cohort study in Sweden.
Alzheimers Dement. 2021 Sep 9. doi: 10.1002/alz.12462.
PubMed Abstract available

CHATTERJEE P, Pedrini S, Ashton NJ, Tegg M, et al
Diagnostic and prognostic plasma biomarkers for preclinical Alzheimer's disease.
Alzheimers Dement. 2021 Sep 8. doi: 10.1002/alz.12447.
PubMed Abstract available

MARTERSTECK A, Sridhar J, Coventry C, Weintraub S, et al
Relationships among tau burden, atrophy, age, and naming in the aphasic variant of Alzheimer's disease.
Alzheimers Dement. 2021 Sep 8. doi: 10.1002/alz.12445.
PubMed Abstract available

LOGSDON AF, Francis KL, Richardson NE, Hu SJ, et al
Decoding perineuronal net glycan sulfation patterns in the Alzheimer's disease brain.
Alzheimers Dement. 2021 Sep 5. doi: 10.1002/alz.12451.
PubMed Abstract available

MA Y, Yu L, Olah M, Smith R, et al
Epigenomic features related to microglia are associated with attenuated effect of APOE epsilon4 on Alzheimer's disease risk in humans.
Alzheimers Dement. 2021 Sep 5. doi: 10.1002/alz.12425.
PubMed Abstract available

REN RJ, Huang Q, Xu G, Gu K, et al
Association between Alzheimer's disease and risk of cancer: A retrospective cohort study in Shanghai, China.
Alzheimers Dement. 2021 Sep 5. doi: 10.1002/alz.12436.
PubMed Abstract available

PEGUEROLES J, Montal V, Bejanin A, Vilaplana E, et al
AMYQ: An index to standardize quantitative amyloid load across PET tracers.
Alzheimers Dement. 2021;17:1499-1508.
PubMed Abstract available

August 2021

GHAZARIAN AL, Haim T, Sauma S, Katiyar P, et al
National Institute on Aging seed funding enables Alzheimer's disease startups to reach key value inflection points.
Alzheimers Dement. 2021 Aug 10. doi: 10.1002/alz.12392.
PubMed Abstract available

WANG Q, Davis PB, Gurney ME, Xu R, et al
COVID-19 and dementia: Analyses of risk, disparity, and outcomes from electronic health records in the US.
Alzheimers Dement. 2021;17:1297-1306.
PubMed Abstract available

PIERUCCINI-FARIA F, Black SE, Masellis M, Smith EE, et al
Gait variability across neurodegenerative and cognitive disorders: Results from the Canadian Consortium of Neurodegeneration in Aging (CCNA) and the Gait and Brain Study.
Alzheimers Dement. 2021;17:1317-1328.
PubMed Abstract available

BAUCKNEHT M, Chincarini A, Brendel M, Rominger A, et al
Associations among education, age, and the dementia with Lewy bodies (DLB) metabolic pattern: A European-DLB consortium project.
Alzheimers Dement. 2021;17:1277-1286.
PubMed Abstract available

GIANATTASIO KZ, Bennett EE, Wei J, Mehrotra ML, et al
Generalizability of findings from a clinical sample to a community-based sample: A comparison of ADNI and ARIC.
Alzheimers Dement. 2021;17:1265-1276.
PubMed Abstract available

July 2021

GARNIER-CRUSSARD A, Bougacha S, Wirth M, Dautricourt S, et al
White matter hyperintensity topography in Alzheimer's disease and links to cognition.
Alzheimers Dement. 2021 Jul 28. doi: 10.1002/alz.12410.
PubMed Abstract available

BOADA M, Rodrigo A, Jessen F, Wimblad B, et al
Complementary pre-screening strategies to uncover hidden prodromal and mild Alzheimer's disease: Results from the MOPEAD project.
Alzheimers Dement. 2021 Jul 26. doi: 10.1002/alz.12441.
PubMed Abstract available

HOSCHEIDT S, Sanderlin AH, Baker LD, Jung Y, et al
Mediterranean and Western diet effects on Alzheimer's disease biomarkers, cerebral perfusion, and cognition in mid-life: A randomized trial.
Alzheimers Dement. 2021 Jul 26. doi: 10.1002/alz.12421.
PubMed Abstract available

VAN HARTEN AC, Wiste HJ, Weigand SD, Mielke MM, et al
Detection of Alzheimer's disease amyloid beta 1-42, p-tau, and t-tau assays.
Alzheimers Dement. 2021 Jul 26. doi: 10.1002/alz.12406.
PubMed Abstract available

KULMINSKI AM, Philipp I, Loika Y, He L, et al
Protective association of the epsilon2/epsilon3 heterozygote with Alzheimer's disease is strengthened by TOMM40-APOE variants in men.
Alzheimers Dement. 2021 Jul 26. doi: 10.1002/alz.12413.
PubMed Abstract available

BOCHE D, Gordon MN
Diversity of transcriptomic microglial phenotypes in aging and Alzheimer's disease.
Alzheimers Dement. 2021 Jul 5. doi: 10.1002/alz.12389.
PubMed Abstract available

BAO H, Liu Y, Zhang M, Chen Z, et al
Increased beta-site APP cleaving enzyme 1-mediated insulin receptor cleavage in type 2 diabetes mellitus with cognitive impairment.
Alzheimers Dement. 2021;17:1097-1108.
PubMed Abstract available

June 2021

ZHANG X, Farrell JJ, Tong T, Hu J, et al
Association of mitochondrial variants and haplogroups identified by whole exome sequencing with Alzheimer's disease.
Alzheimers Dement. 2021 Jun 20. doi: 10.1002/alz.12396.
PubMed Abstract available

TEERLINK CC, Miller JB, Vance EL, Staley LA, et al
Analysis of high-risk pedigrees identifies 12 candidate variants for Alzheimer's disease.
Alzheimers Dement. 2021 Jun 20. doi: 10.1002/alz.12397.
PubMed Abstract available

ZHONG W, Wu A, Berglund K, Gu X, et al
Pathogenesis of sporadic Alzheimer's disease by deficiency of NMDA receptor subunit GluN3A.
Alzheimers Dement. 2021 Jun 20. doi: 10.1002/alz.12398.
PubMed Abstract available

JANELIDZE S, Palmqvist S, Leuzy A, Stomrud E, et al
Detecting amyloid positivity in early Alzheimer's disease using combinations of plasma Abeta42/Abeta40 and p-tau.
Alzheimers Dement. 2021 Jun 20. doi: 10.1002/alz.12395.
PubMed Abstract available

BIRKENBIHL C, Salimi Y, Frohlich H
Unraveling the heterogeneity in Alzheimer's disease progression across multiple cohorts and the implications for data-driven disease modeling.
Alzheimers Dement. 2021 Jun 9. doi: 10.1002/alz.12387.
PubMed Abstract available

LOPEZ-RODRIGUEZ AB, Hennessy E, Murray CL, Nazmi A, et al
Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL-1beta drives amplified responses in primed astrocytes and neuronal network dysfunction.
Alzheimers Dement. 2021 Jun 3. doi: 10.1002/alz.12341.
PubMed Abstract available

TEMP AGM, Lutz MW, Trepel D, Tang Y, et al
How Bayesian statistics may help answer some of the controversial questions in clinical research on Alzheimer's disease.
Alzheimers Dement. 2021;17:917-919.
PubMed

FRANZMEIER N, Ossenkoppele R, Brendel M, Rubinski A, et al
The BIN1 rs744373 Alzheimer's disease risk SNP is associated with faster Abeta-associated tau accumulation and cognitive decline.
Alzheimers Dement. 2021 Jun 1. doi: 10.1002/alz.12371.
PubMed Abstract available

RICHARD E, den Brok MGHE, van Gool WA
Bayes analysis supports null hypothesis of anti-amyloid beta therapy in Alzheimer's disease.
Alzheimers Dement. 2021;17:1051-1055.
PubMed Abstract available

DE ERAUSQUIN GA, Snyder H, Carrillo M, Hosseini AA, et al
The chronic neuropsychiatric sequelae of COVID-19: The need for a prospective study of viral impact on brain functioning.
Alzheimers Dement. 2021;17:1056-1065.
PubMed Abstract available

May 2021

SEXTON CE, Anstey KJ, Baldacci F, Barnum CJ, et al
Alzheimer's disease research progress in Australia: The Alzheimer's Association International Conference Satellite Symposium in Sydney.
Alzheimers Dement. 2021 May 31. doi: 10.1002/alz.12380.
PubMed Abstract available

O'BRYANT SE, Zhang F, Petersen M, Hall JR, et al
A blood screening tool for detecting mild cognitive impairment and Alzheimer's disease among community-dwelling Mexican Americans and non-Hispanic Whites: A method for increasing representation of diverse populations in clinical research.
Alzheimers Dement. 2021 May 31. doi: 10.1002/alz.12382.
PubMed Abstract available

PANNUZZO M
Beta-amyloid pore linked to controlled calcium influx into the cell: A new paradigm for Alzheimer's Disease.
Alzheimers Dement. 2021 May 29. doi: 10.1002/alz.12373.
PubMed Abstract available

SCHWAHN C, Frenzel S, Holtfreter B, Van der Auwera S, et al
Effect of periodontal treatment on preclinical Alzheimer's disease-Results of a trial emulation approach.
Alzheimers Dement. 2021 May 29. doi: 10.1002/alz.12378.
PubMed Abstract available

RAJAN KB, Weuve J, Barnes LL, McAninch EA, et al
Population estimate of people with clinical Alzheimer's disease and mild cognitive impairment in the United States (2020-2060).
Alzheimers Dement. 2021 May 27. doi: 10.1002/alz.12362.
PubMed Abstract available

HAMPEL H, Shaw LM, Aisen P, Chen C, et al
State-of-the-art of lumbar puncture and its place in the journey of patients with Alzheimer's disease.
Alzheimers Dement. 2021 May 27. doi: 10.1002/alz.12372.
PubMed Abstract available

JIANG Y, Zhou X, Ip FC, Chan P, et al
Large-scale plasma proteomic profiling identifies a high-performance biomarker panel for Alzheimer's disease screening and staging.
Alzheimers Dement. 2021 May 25. doi: 10.1002/alz.12369.
PubMed Abstract available

APOSTOLOVA LG, Aisen P, Eloyan A, Fagan A, et al
The Longitudinal Early-onset Alzheimer's Disease Study (LEADS): Framework and methodology.
Alzheimers Dement. 2021 May 21. doi: 10.1002/alz.12350.
PubMed Abstract available

STERN Y, Stallard E, Kinosian B, Zhu C, et al
Validation and demonstration of a new comprehensive model of Alzheimer's disease progression.
Alzheimers Dement. 2021 May 14. doi: 10.1002/alz.12336.
PubMed Abstract available

HONG S, Dobricic V, Ohlei O, Bos I, et al
TMEM106B and CPOX are genetic determinants of cerebrospinal fluid Alzheimer's disease biomarker levels.
Alzheimers Dement. 2021 May 14. doi: 10.1002/alz.12330.
PubMed Abstract available

LIBIGER O, Shaw LM, Watson MH, Nairn AC, et al
Longitudinal CSF proteomics identifies NPTX2 as a prognostic biomarker of Alzheimer's disease.
Alzheimers Dement. 2021 May 13. doi: 10.1002/alz.12353.
PubMed Abstract available

GUSTAVSSON A, Raket LL, Lilja M, Rutten-Jacobs L, et al
Health utility in preclinical and prodromal Alzheimer's disease for establishing the value of new disease-modifying treatments-EQ-5D data from the Swedish BioFINDER study.
Alzheimers Dement. 2021 May 13. doi: 10.1002/alz.12355.
PubMed Abstract available

MORGAN DG, Mielke MM
Knowledge gaps in Alzheimer's disease immune biomarker research.
Alzheimers Dement. 2021 May 13. doi: 10.1002/alz.12342.
PubMed Abstract available

OSSENKOPPELE R, Hansson O
Towards clinical application of tau PET tracers for diagnosing dementia due to Alzheimer's disease.
Alzheimers Dement. 2021 May 13. doi: 10.1002/alz.12356.
PubMed Abstract available

MADRASI K, Das R, Mohmmadabdul H, Lin L, et al
Systematic in silico analysis of clinically tested drugs for reducing amyloid-beta plaque accumulation in Alzheimer's disease.
Alzheimers Dement. 2021 May 2. doi: 10.1002/alz.12312.
PubMed Abstract available

Association commits $14 million to novel drug trials in rare form of Alzheimer's.
Alzheimers Dement. 2021;17:910.
PubMed

STANLEY J, Howlett SE, Dunn T, Rockwood K, et al
The Clinician's Interview-Based Impression of Change (Plus caregiver input) and goal attainment in two dementia drug trials: Clinical meaningfulness and the initial treatment response.
Alzheimers Dement. 2021;17:856-865.
PubMed Abstract available

MIELKE MM, Przybelski SA, Lesnick TG, Kern S, et al
Comparison of CSF neurofilament light chain, neurogranin, and tau to MRI markers.
Alzheimers Dement. 2021;17:801-812.
PubMed Abstract available

WOODWORTH DC, Nguyen HL, Khan Z, Kawas CH, et al
Utility of MRI in the identification of hippocampal sclerosis of aging.
Alzheimers Dement. 2021;17:847-855.
PubMed Abstract available

COUSINS KAQ, Phillips JS, Irwin DJ, Lee EB, et al
ATN incorporating cerebrospinal fluid neurofilament light chain detects frontotemporal lobar degeneration.
Alzheimers Dement. 2021;17:822-830.
PubMed Abstract available

April 2021

RANASINGHE KG, Petersen C, Kudo K, Mizuiri D, et al
Reduced synchrony in alpha oscillations during life predicts post mortem neurofibrillary tangle density in early-onset and atypical Alzheimer's disease.
Alzheimers Dement. 2021 Apr 21. doi: 10.1002/alz.12349.
PubMed Abstract available

LI X, Tsolis KC, Koper MJ, Ronisz A, et al
Sequence of proteome profiles in preclinical and symptomatic Alzheimer's disease.
Alzheimers Dement. 2021 Apr 19. doi: 10.1002/alz.12345.
PubMed Abstract available

BABILONI C, Arakaki X, Azami H, Bennys K, et al
Measures of resting state EEG rhythms for clinical trials in Alzheimer's disease: Recommendations of an expert panel.
Alzheimers Dement. 2021 Apr 15. doi: 10.1002/alz.12311.
PubMed Abstract available

MOELLER S, Sridhar J, Martersteck A, Coventry C, et al
Functional decline in the aphasic variant of Alzheimer's disease.
Alzheimers Dement. 2021 Apr 8. doi: 10.1002/alz.12331.
PubMed Abstract available

MOLONEY CM, Lowe VJ, Murray ME
Visualization of neurofibrillary tangle maturity in Alzheimer's disease: A clinicopathologic perspective for biomarker research.
Alzheimers Dement. 2021 Apr 2. doi: 10.1002/alz.12321.
PubMed Abstract available

PROKOPENKO D, Morgan SL, Mullin K, Hofmann O, et al
Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development.
Alzheimers Dement. 2021 Apr 2. doi: 10.1002/alz.12319.
PubMed Abstract available

SABBAGH MN, Cummings J
Open Peer Commentary to "Failure to demonstrate efficacy of aducanumab: An analysis of the EMERGE and ENGAGE Trials as reported by Biogen December 2019".
Alzheimers Dement. 2021;17:702-703.
PubMed

KULLER LH, Lopez OL
ENGAGE and EMERGE: Truth and consequences?
Alzheimers Dement. 2021;17:692-695.
PubMed Abstract available

BRAY MJC, Richey LN, Bryant BR, Krieg A, et al
Traumatic brain injury alters neuropsychiatric symptomatology in all-cause dementia.
Alzheimers Dement. 2021;17:686-691.
PubMed Abstract available

PLANCHE V, Bouteloup V, Mangin JF, Dubois B, et al
Clinical relevance of brain atrophy subtypes categorization in memory clinics.
Alzheimers Dement. 2021;17:641-652.
PubMed Abstract available

STAFFARONI AM, Asken BM, Casaletto KB, Fonseca C, et al
Development and validation of the Uniform Data Set (v3.0) executive function composite score (UDS3-EF).
Alzheimers Dement. 2021;17:574-583.
PubMed Abstract available

KNOPMAN DS, Jones DT, Greicius MD
Failure to demonstrate efficacy of aducanumab: An analysis of the EMERGE and ENGAGE trials as reported by Biogen, December 2019.
Alzheimers Dement. 2021;17:696-701.
PubMed Abstract available

March 2021

CHONG JR, Ashton NJ, Karikari TK, Tanaka T, et al
Plasma P-tau181 to Abeta42 ratio is associated with brain amyloid burden and hippocampal atrophy in an Asian cohort of Alzheimer's disease patients with concomitant cerebrovascular disease.
Alzheimers Dement. 2021 Mar 31. doi: 10.1002/alz.12332.
PubMed Abstract available

SHI L, Winchester LM, Westwood S, Baird AL, et al
Replication study of plasma proteins relating to Alzheimer's pathology.
Alzheimers Dement. 2021 Mar 31. doi: 10.1002/alz.12322.
PubMed Abstract available

HANSSON O, Batrla R, Brix B, Carrillo MC, et al
The Alzheimer's Association international guidelines for handling of cerebrospinal fluid for routine clinical measurements of amyloid beta and tau.
Alzheimers Dement. 2021 Mar 31. doi: 10.1002/alz.12316.
PubMed Abstract available

Register for May AAIC(R) Satellite Symposium and second Latinos & Alzheimer's symposium.
Alzheimers Dement. 2021 Mar 31. doi: 10.1002/alz.12337.
PubMed

AKHTER-KHAN SC, Tao Q, Ang TFA, Itchapurapu IS, et al
Associations of loneliness with risk of Alzheimer's disease dementia in the Framingham Heart Study.
Alzheimers Dement. 2021 Mar 24. doi: 10.1002/alz.12327.
PubMed Abstract available

2021 Alzheimer's disease facts and figures.
Alzheimers Dement. 2021 Mar 23. doi: 10.1002/alz.12328.
PubMed Abstract available

BECKMAN D, Chakrabarty P, Ott S, Dao A, et al
A novel tau-based rhesus monkey model of Alzheimer's pathogenesis.
Alzheimers Dement. 2021 Mar 18. doi: 10.1002/alz.12318.
PubMed Abstract available

KOCIOLEK AJ, Fernandez KK, Jin Z, Cosentino S, et al
Extrapyramidal signs and Alzheimer's disease prognosis in a multiethnic, community-based sample of demented elders.
Alzheimers Dement. 2021 Mar 12. doi: 10.1002/alz.12309.
PubMed Abstract available

DISBROW E, Stokes KY, Ledbetter C, Patterson J, et al
Plasma hydrogen sulfide: A biomarker of Alzheimer's disease and related dementias.
Alzheimers Dement. 2021 Mar 12. doi: 10.1002/alz.12305.
PubMed Abstract available

FALGAS N, Walsh CM, Neylan TC, Grinberg LT, et al
Deepen into sleep and wake patterns across Alzheimer's disease phenotypes.
Alzheimers Dement. 2021 Mar 12. doi: 10.1002/alz.12304.
PubMed Abstract available

RAHMAN M, White EM, Mills C, Thomas KS, et al
Rural-urban differences in diagnostic incidence and prevalence of Alzheimer's disease and related dementias.
Alzheimers Dement. 2021 Mar 4. doi: 10.1002/alz.12285.
PubMed Abstract available

SALVADO G, Mila-Aloma M, Shekari M, Minguillon C, et al
Cerebral amyloid-beta load is associated with neurodegeneration and gliosis: Mediation by p-tau and interactions with risk factors early in the Alzheimer's continuum.
Alzheimers Dement. 2021 Mar 4. doi: 10.1002/alz.12245.
PubMed Abstract available

TURNER DA, Degan S, Hoffmann U, Galeffi F, et al
CVN-AD Alzheimer's mice show premature reduction in neurovascular coupling in response to spreading depression and anoxia compared to aged controls.
Alzheimers Dement. 2021 Mar 3. doi: 10.1002/alz.12289.
PubMed Abstract available

MASEREJIAN N, Krzywy H, Eaton S, Galvin JE, et al
Cognitive measures lacking in EHR prior to dementia or Alzheimer's disease diagnosis.
Alzheimers Dement. 2021 Mar 3. doi: 10.1002/alz.12280.
PubMed Abstract available

SAITO ER, Miller JB, Harari O, Cruchaga C, et al
Alzheimer's disease alters oligodendrocytic glycolytic and ketolytic gene expression.
Alzheimers Dement. 2021 Mar 2. doi: 10.1002/alz.12310.
PubMed Abstract available

LI Y, Xiong C, Aschenbrenner AJ, Chang CH, et al
Item response theory analysis of the Clinical Dementia Rating.
Alzheimers Dement. 2021;17:534-542.
PubMed Abstract available

FANI L, Ahmad S, Ikram MK, Ghanbari M, et al
Immunity and amyloid beta, total tau and neurofilament light chain: Findings from a community-based cohort study.
Alzheimers Dement. 2021;17:446-456.
PubMed Abstract available

GRANOT-HERSHKOVITZ E, Tarraf W, Kurniansyah N, Daviglus M, et al
APOE alleles' association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos-investigation of neurocognitive aging (HCHS/SOL).
Alzheimers Dement. 2021;17:466-474.
PubMed Abstract available

February 2021

ASHFORD MT, Veitch DP, Neuhaus J, Nosheny RL, et al
The search for a convenient procedure to detect one of the earliest signs of Alzheimer's disease: A systematic review of the prediction of brain amyloid status.
Alzheimers Dement. 2021 Feb 13. doi: 10.1002/alz.12253.
PubMed Abstract available

BRICKMAN AM, Manly JJ, Honig LS, Sanchez D, et al
Plasma p-tau181, p-tau217, and other blood-based Alzheimer's disease biomarkers in a multi-ethnic, community study.
Alzheimers Dement. 2021 Feb 13. doi: 10.1002/alz.12301.
PubMed Abstract available

IZZO NJ, Yuede CM, LaBarbera KM, Limegrover CS, et al
Preclinical and clinical biomarker studies of CT1812: A novel approach to Alzheimer's disease modification.
Alzheimers Dement. 2021 Feb 8. doi: 10.1002/alz.12302.
PubMed Abstract available

BLEILE L
Alzheimer's Association Update.
Alzheimers Dement. 2021 Feb 4. doi: 10.1002/alz.12306.
PubMed

WANG R, Qiu C, Dintica CS, Shang Y, et al
Shared risk and protective factors between Alzheimer's disease and ischemic stroke: A population-based longitudinal study.
Alzheimers Dement. 2021 Feb 1. doi: 10.1002/alz.12203.
PubMed Abstract available

GUZMAN-VELEZ E, Zetterberg H, Fox-Fuller JT, Vila-Castelar C, et al
Associations between plasma neurofilament light, in vivo brain pathology, and cognition in non-demented individuals with autosomal-dominant Alzheimer's disease.
Alzheimers Dement. 2021 Feb 1. doi: 10.1002/alz.12248.
PubMed Abstract available

GRISWOLD AJ, Celis K, Bussies PL, Rajabli F, et al
Increased APOE epsilon4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds.
Alzheimers Dement. 2021 Feb 1. doi: 10.1002/alz.12287.
PubMed Abstract available

HAGHANI A, Thorwald M, Morgan TE, Finch CE, et al
The APOE gene cluster responds to air pollution factors in mice with coordinated expression of genes that differs by age in humans.
Alzheimers Dement. 2021;17:175-190.
PubMed Abstract available

CHEN XQ, Salehi A, Pearn ML, Overk C, et al
Targeting increased levels of APP in Down syndrome: Posiphen-mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse model.
Alzheimers Dement. 2021;17:271-292.
PubMed Abstract available

BLUE EE, Thornton TA, Kooperberg C, Liu S, et al
Non-coding variants in MYH11, FZD3, and SORCS3 are associated with dementia in women.
Alzheimers Dement. 2021;17:215-225.
PubMed Abstract available

DE LEEUW FA, Karamujic-Comic H, Tijms BM, Peeters CFW, et al
Circulating metabolites are associated with brain atrophy and white matter hyperintensities.
Alzheimers Dement. 2021;17:205-214.
PubMed Abstract available

January 2021

AYTON S, Portbury S, Kalinowski P, Agarwal P, et al
Regional brain iron associated with deterioration in Alzheimer's disease: A large cohort study and theoretical significance.
Alzheimers Dement. 2021 Jan 25. doi: 10.1002/alz.12282.
PubMed Abstract available

SIMREN J, Leuzy A, Karikari TK, Hye A, et al
The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's disease.
Alzheimers Dement. 2021 Jan 25. doi: 10.1002/alz.12283.
PubMed Abstract available

GERMANN J, Elias GJB, Boutet A, Narang K, et al
Brain structures and networks responsible for stimulation-induced memory flashbacks during forniceal deep brain stimulation for Alzheimer's disease.
Alzheimers Dement. 2021 Jan 21. doi: 10.1002/alz.12238.
PubMed Abstract available

BRYAN J, Mandan A, Kamat G, Gottschalk WK, et al
Likelihood ratio statistics for gene set enrichment in Alzheimer's disease pathways.
Alzheimers Dement. 2021 Jan 21. doi: 10.1002/alz.12223.
PubMed Abstract available

LUCKETT PH, McCullough A, Gordon BA, Strain J, et al
Modeling autosomal dominant Alzheimer's disease with machine learning.
Alzheimers Dement. 2021 Jan 21. doi: 10.1002/alz.12259.
PubMed Abstract available

LI HD, Funk CC, McFarland K, Dammer EB, et al
Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease.
Alzheimers Dement. 2021 Jan 21. doi: 10.1002/alz.12254.
PubMed Abstract available

Alzheimer's Association International Conference Neuroscience Next focused on early career researchers across all of neuroscience.
Alzheimers Dement. 2021;17:138-139.
PubMed

CHIARI A, Vinceti G, Adani G, Tondelli M, et al
Epidemiology of early onset dementia and its clinical presentations in the province of Modena, Italy.
Alzheimers Dement. 2021;17:81-88.
PubMed Abstract available

December 2020

VAN HULLE C, Jonaitis EM, Betthauser TJ, Batrla R, et al
An examination of a novel multipanel of CSF biomarkers in the Alzheimer's disease clinical and pathological continuum.
Alzheimers Dement. 2020 Dec 18. doi: 10.1002/alz.12204.
PubMed Abstract available

LYSSENKO NN, Pratico D
ABCA7 and the altered lipidostasis hypothesis of Alzheimer's disease.
Alzheimers Dement. 2020 Dec 17. doi: 10.1002/alz.12220.
PubMed Abstract available

MOHAMMED H
Recognizing African-American contributions to neurology: The role of Solomon Carter Fuller (1872-1953) in Alzheimer's disease research.
Alzheimers Dement. 2020 Dec 15. doi: 10.1002/alz.12183.
PubMed Abstract available

AUDRAIN M, Haure-Mirande JV, Mleczko J, Wang M, et al
Reactive or transgenic increase in microglial TYROBP reveals a TREM2-independent TYROBP-APOE link in wild-type and Alzheimer's-related mice.
Alzheimers Dement. 2020 Dec 12. doi: 10.1002/alz.12256.
PubMed Abstract available

KIM YW, Al-Ramahi I, Koire A, Wilson SJ, et al
Harnessing the paradoxical phenotypes of APOE varepsilon2 and APOE varepsilon4 to identify genetic modifiers in Alzheimer's disease.
Alzheimers Dement. 2020 Dec 7. doi: 10.1002/alz.12240.
PubMed Abstract available

FRYE BM, Craft S, Register TC, Andrews RN, et al
Diet, psychosocial stress, and Alzheimer's disease-related neuroanatomy in female nonhuman primates.
Alzheimers Dement. 2020 Dec 3. doi: 10.1002/alz.12232.
PubMed Abstract available

November 2020

KARIKARI TK, Emersic A, Vrillon A, Lantero-Rodriguez J, et al
Head-to-head comparison of clinical performance of CSF phospho-tau T181 and T217 biomarkers for Alzheimer's disease diagnosis.
Alzheimers Dement. 2020 Nov 30. doi: 10.1002/alz.12236.
PubMed Abstract available

LLIBRE-GUERRA JJ, Li Y, Allegri RF, Mendez PC, et al
Dominantly inherited Alzheimer's disease in Latin America: Genetic heterogeneity and clinical phenotypes.
Alzheimers Dement. 2020 Nov 23. doi: 10.1002/alz.12227.
PubMed Abstract available

DUENAS MR, Snyder PJ
Alzheimer's team care approach-akin to diabetes-in the development, validation, and population assessment of retinal biomarkers for disease.
Alzheimers Dement. 2020 Nov 23. doi: 10.1002/alz.12234.
PubMed Abstract available

SPENCER BE, Digma LA, Jennings RG, Brewer JB, et al
Gene- and age-informed screening for preclinical Alzheimer's disease trials.
Alzheimers Dement. 2020 Nov 23. doi: 10.1002/alz.12207.
PubMed Abstract available

HITHERSAY R, Baksh RA, Startin CM, Wijeratne P, et al
Optimal age and outcome measures for Alzheimer's disease prevention trials in people with Down syndrome.
Alzheimers Dement. 2020 Nov 23. doi: 10.1002/alz.12222.
PubMed Abstract available

PENTZ R, Iulita MF, Ducatenzeiler A, Videla L, et al
Nerve growth factor (NGF) pathway biomarkers in Down syndrome prior to and after the onset of clinical Alzheimer's disease: A paired CSF and plasma study.
Alzheimers Dement. 2020 Nov 23. doi: 10.1002/alz.12229.
PubMed Abstract available

MONTAL V, Vilaplana E, Pegueroles J, Bejanin A, et al
Biphasic cortical macro- and microstructural changes in autosomal dominant Alzheimer's disease.
Alzheimers Dement. 2020 Nov 16. doi: 10.1002/alz.12224.
PubMed Abstract available

JESSEN F, Kleineidam L, Wolfsgruber S, Bickel H, et al
Prediction of dementia of Alzheimer type by different types of subjective cognitive decline.
Alzheimers Dement. 2020 Nov 2. doi: 10.1002/alz.12163.
PubMed Abstract available

Alzheimer's Association pays tribute to former Chief Science Officer William (Bill) Thies, PhD.
Alzheimers Dement. 2020;16:1600-1605.
PubMed

October 2020

SOHEILI-NEZHAD S, van der Linden RJ, Olde Rikkert M, Sprooten E, et al
Long genes are more frequently affected by somatic mutations and show reduced expression in Alzheimer's disease: Implications for disease etiology.
Alzheimers Dement. 2020 Oct 19. doi: 10.1002/alz.12211.
PubMed Abstract available

ARNSTEN AFT, Datta D, Tredici KD, Braak H, et al
Hypothesis: Tau pathology is an initiating factor in sporadic Alzheimer's disease.
Alzheimers Dement. 2020 Oct 19. doi: 10.1002/alz.12192.
PubMed Abstract available

WESSELS AM, Lines C, Stern RA, Kost J, et al
Cognitive outcomes in trials of two BACE inhibitors in Alzheimer's disease.
Alzheimers Dement. 2020 Oct 13. doi: 10.1002/alz.12164.
PubMed Abstract available

MECCA AP, van Dyck CH
Alzheimer's & Dementia: The Journal of the Alzheimer's Association.
Alzheimers Dement. 2020 Oct 12. doi: 10.1002/alz.12190.
PubMed

SNYDER PJ, Alber J, Alt C, Bain LJ, et al
Retinal imaging in Alzheimer's and neurodegenerative diseases.
Alzheimers Dement. 2020 Oct 8. doi: 10.1002/alz.12179.
PubMed Abstract available

THUNELL J, Chen Y, Joyce G, Barthold D, et al
Drug therapies for chronic conditions and risk of Alzheimer's disease and related dementias: A scoping review.
Alzheimers Dement. 2020 Oct 8. doi: 10.1002/alz.12175.
PubMed Abstract available

JAIN S, Rosenbaum PR, Reiter JG, Hoffman G, et al
Using Medicare claims in identifying Alzheimer's disease and related dementias.
Alzheimers Dement. 2020 Oct 8. doi: 10.1002/alz.12199.
PubMed Abstract available

HOU X, Watzlawik JO, Cook C, Liu CC, et al
Mitophagy alterations in Alzheimer's disease are associated with granulovacuolar degeneration and early tau pathology.
Alzheimers Dement. 2020 Oct 8. doi: 10.1002/alz.12198.
PubMed Abstract available

BUBU OM, Umasabor-Bubu OQ, Turner AD, Parekh A, et al
Self-reported obstructive sleep apnea, amyloid and tau burden, and Alzheimer's disease time-dependent progression.
Alzheimers Dement. 2020 Oct 8. doi: 10.1002/alz.12184.
PubMed Abstract available

August 2020

DENNY A, Streitz M, Stock K, Balls-Berry JE, et al
Perspective on the "African American participation in Alzheimer disease research: Effective strategies" workshop, 2018.
Alzheimers Dement. 2020 Aug 17. doi: 10.1002/alz.12160.
PubMed Abstract available

April 2020

CABALLERO MAA, Song Z, Rubinski A, Duering M, et al
Age-dependent amyloid deposition is associated with white matter alterations in cognitively normal adults during the adult life span.
Alzheimers Dement. 2020;16:651-661.
PubMed Abstract available

March 2020

LOWE VJ, Lundt ES, Albertson SM, Min HK, et al
Tau-positron emission tomography correlates with neuropathology findings.
Alzheimers Dement. 2020;16:561-571.
PubMed Abstract available

PAPP KV, Buckley R, Mormino E, Maruff P, et al
Clinical meaningfulness of subtle cognitive decline on longitudinal testing in preclinical AD.
Alzheimers Dement. 2020;16:552-560.
PubMed Abstract available

February 2020

ANTONELL A, Tort-Merino A, Rios J, Balasa M, et al
Synaptic, axonal damage and inflammatory cerebrospinal fluid biomarkers in neurodegenerative dementias.
Alzheimers Dement. 2020;16:262-272.
PubMed Abstract available

ANGULO SL, Henzi T, Neymotin SA, Suarez MD, et al
Amyloid pathology-produced unexpected modifications of calcium homeostasis in hippocampal subicular dendrites.
Alzheimers Dement. 2020;16:251-261.
PubMed Abstract available

January 2020

KAPLOW J, Vandijck M, Gray J, Kanekiyo M, et al
Concordance of Lumipulse cerebrospinal fluid t-tau/Abeta42 ratio with amyloid PET status.
Alzheimers Dement. 2020;16:144-152.
PubMed Abstract available

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