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  Alzheimer's Disease

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Articles published in Brain Res

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Single Articles


    December 2025
  1. YUAN J, Zhang J, Zhang H, Tu Y, et al
    Propofol induces mitochondrial dysfunction in hippocampal neurons and postoperative cognitive dysfunction in male 3xTg-AD mice by blocking ESRRG-mediated HSD11B2 transcription.
    Brain Res. 2025;1869:150035.
    PubMed     Abstract available


    November 2025
  2. SARDARI M, Sahafi OH, Rezayof A
    Mitochondria serve as indispensable components of neuron-glia crosstalk in the trajectory of Alzheimer's disease.
    Brain Res. 2025 Nov 18:150040. doi: 10.1016/j.brainres.2025.150040.
    PubMed     Abstract available


  3. VLACHOS I, Moschovos C, Apostolakopoulou L, Karasavvidou K, et al
    Resting EEG partial coherence demonstrates increased gamma range central functional connectivity in amnestic mild cognitive impairment.
    Brain Res. 2025;1867:149973.
    PubMed     Abstract available


  4. SHARMA A, Singh TG
    Next-generation neurotherapeutics: mechanistic insights on monoclonal antibodies in Alzheimer's disease.
    Brain Res. 2025;1870:150047.
    PubMed     Abstract available


    October 2025
  5. LIU Z, Kuang L, Zhou X, Zhao J, et al
    Effect of the plasma lipidome, immune cells, inflammatory proteins, gut microbiota, and plasma metabolites on Alzheimer's Disease: A two-sample Mendelian randomized study and mediation analysis.
    Brain Res. 2025;1869:150009.
    PubMed     Abstract available


  6. BI D, Gao B, Shen Y, Dai Z, et al
    Traumatic brain injury and neurodegenerative diseases: the role of axonal injury and amyloid-beta.
    Brain Res. 2025;1865:149873.
    PubMed     Abstract available


  7. ISMAIL A, Al-Kuraishy HM, Al-Gareeb AI, Albuhadily AK, et al
    Astrocyte response in Alzheimer's disease: Good or bad?
    Brain Res. 2025 Oct 6:149971. doi: 10.1016/j.brainres.2025.149971.
    PubMed     Abstract available


  8. DING Z, Wang J, Ding W, Duan Y, et al
    Calycosin improved long-term memory impairment in the very early of APP/PS1 mice.
    Brain Res. 2025;1864:149789.
    PubMed     Abstract available


  9. GENG D, Liu A, Yan Y, Zheng W, et al
    Intermittent ELF-MF exposure effectively ameliorates pathologic features associated with adult AD mice.
    Brain Res. 2025;1864:149796.
    PubMed     Abstract available


    September 2025
  10. WANG Y, Zhao D, Kong T, Ni Y, et al
    Associations between reproductive milestones and Alzheimer's disease risk: a Mendelian randomization study.
    Brain Res. 2025;1867:149972.
    PubMed     Abstract available


  11. KAKOTY V, Goh KW, Kesharwani P, Ko YT, et al
    BNIP3L/NIX-mediated mitophagy: Future directions in Alzheimer's disease.
    Brain Res. 2025;1867:149970.
    PubMed     Abstract available


  12. MAK KK, Nam KJ, Chuang YF, Chen LK, et al
    Matrix metalloproteinases and tissue inhibitors of metalloproteinases as the biomarkers of Alzheimer's disease: a meta-analysis.
    Brain Res. 2025 Sep 23:149954. doi: 10.1016/j.brainres.2025.149954.
    PubMed     Abstract available


  13. AKASH A, Ahamed M, Porel P, Aran KR, et al
    Galectin-3 in Alzheimer's disease: pathological roles, biomarker potential, and therapeutic implications.
    Brain Res. 2025 Sep 19:149949. doi: 10.1016/j.brainres.2025.149949.
    PubMed     Abstract available


  14. HU X, Morihara R, Fukui Y, Bian Y, et al
    Spearmint extract Neumentix downregulates amyloid-beta accumulation by promoting phagocytosis in APP23 mice.
    Brain Res. 2025;1863:149752.
    PubMed     Abstract available


  15. SHENG J, Zhu H, Zhou R, Zhang Q, et al
    Bridging the gap between structural and metabolic neuroimaging via MRI-to-PET synthesis: A tri-attention enhanced GAN approach.
    Brain Res. 2025;1862:149691.
    PubMed     Abstract available


    August 2025
  16. CAM OZUNLU SA, Uysal F, Tatli Dogan H, Parlar A, et al
    Thymoquinone ameliorates cognitive impairment and neuroinflammation in an amyloid-beta-induced rat model of Alzheimer's disease.
    Brain Res. 2025;1866:149918.
    PubMed     Abstract available


  17. LI J, Wang C, Zhang JH, Cai JM, et al
    Expression of concern: "Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer's disease by reduction of oxidative stress" [BRAIN RES, Volume 1328 (2010) 152-161].
    Brain Res. 2025;1861:149685.
    PubMed    


  18. MOHAN M, Mannan A, Singh S, Singh TG, et al
    Unlocking the cellular mystery: how proton pump inhibitors may alter the dementia landscape.
    Brain Res. 2025;1861:149702.
    PubMed     Abstract available


  19. LIU B, Ahmad MA, Abbas G, Ahmed U, et al
    From particulates to pathways: environmental exposures and their impact on Alzheimer's disease.
    Brain Res. 2025 Aug 8:149880. doi: 10.1016/j.brainres.2025.149880.
    PubMed     Abstract available


  20. LIU L, Jiang M, Zhang Y, Lv L, et al
    Acori Tatarinowii Rhizoma inhibited neuroinflammation in Alzheimer's disease rats by modulating the intestinal flora.
    Brain Res. 2025 Aug 8:149878. doi: 10.1016/j.brainres.2025.149878.
    PubMed     Abstract available


    July 2025
  21. ALOUANI Z, Gannour OE, Saleh S, El-Ibrahimi A, et al
    A novel contrastive Dual-Branch Network (CDB-Net) for robust EEG-Based Alzheimer's disease diagnosis.
    Brain Res. 2025;1865:149863.
    PubMed     Abstract available


  22. WANG Y, Mu D, Li Y, Liu C, et al
    Alzheimer's disease: a jigsaw puzzle comprised of different types of programmed cell death pieces.
    Brain Res. 2025;1865:149861.
    PubMed     Abstract available


  23. ISLAM MA, Kshirsagar S, Alvir RV, Pradeepkiran JA, et al
    Overexpressed MicroRNA-455-3p enhances cognitive function in late-onset Alzheimer's disease.
    Brain Res. 2025 Jul 21:149853. doi: 10.1016/j.brainres.2025.149853.
    PubMed     Abstract available


  24. YAO M, Liu A, Song J, Xing L, et al
    The impact of epigenetic and epitranscriptomic modifications on Alzheimer's disease: the mysteries of DNA, RNA, and histone methylation.
    Brain Res. 2025;1865:149852.
    PubMed     Abstract available


  25. SALGADO KDCB, Nascimento RGF, Albuquerque ALS, Oliveira LAM, et al
    Melatonin protects mouse hippocampal neurons from neurotoxicity induced by amyloid beta-peptide(25-35).
    Brain Res. 2025;1859:149637.
    PubMed     Abstract available


  26. BASHIR DJ, Bhat KA, Bashir M
    Deciphering Alzheimer's disease: Molecular mechanisms, preclinical models and strategies to overcome Blood-Brain-Barrier.
    Brain Res. 2025;1863:149828.
    PubMed     Abstract available


  27. BALL BK, Kuhn MK, Fleeman Bechtel RM, Proctor EA, et al
    Metabolites associated with type 2 diabetes and Alzheimer's disease trigger differential intracellular signaling responses in mouse primary neurons.
    Brain Res. 2025;1864:149819.
    PubMed     Abstract available


    June 2025
  28. HE J, Ran M, Tam KY
    An orally administered quinolinium molecule mitigates neuropathology of Alzheimer's disease through modulation of mitochondrial dysfunction and neuroinflammation.
    Brain Res. 2025 Jun 25:149804. doi: 10.1016/j.brainres.2025.149804.
    PubMed     Abstract available


  29. MA XH, Dai H, Liu SY, Liu XN, et al
    Protection of dauricine and daurisoline on PC12 cells damaged by glutamate or Abeta(25-35).
    Brain Res. 2025;1857:149609.
    PubMed     Abstract available


  30. KHAN G, Hussain MS, Khan Y, Fatima R, et al
    Ferroptosis and its contribution to cognitive impairment in Alzheimer's disease: mechanisms and therapeutic potential.
    Brain Res. 2025 Jun 9:149776. doi: 10.1016/j.brainres.2025.149776.
    PubMed     Abstract available


    May 2025
  31. ARIOZ BI, Binokay L, Tastan B, Genc B, et al
    Characterization of tRNA-derived fragments in the small neuron-derived extracellular vesicles of Alzheimer's disease patients.
    Brain Res. 2025;1862:149730.
    PubMed     Abstract available


  32. CHAVEZ-LOPEZ LM, Silvestre-Martinez JH, Del Carmen Lugo-Ibarra K, Castro-Cesena AB, et al
    A comprehensive approach to Alzheimer's Disease: Exploring Nanotechnology, treatment Innovations, and sex differences.
    Brain Res. 2025 May 26:149718. doi: 10.1016/j.brainres.2025.149718.
    PubMed     Abstract available


  33. YANG X, Jiang M, Wu M, Jin X, et al
    Crocin drives intestinal microbiota variation in a rat model of Alzheimer's disease by reducing DKK3 expression.
    Brain Res. 2025;1862:149734.
    PubMed     Abstract available


  34. ZHOU Q, Huang X, Chen Z, Wang F, et al
    Mechanism of Rhizoma Polygonati in the treatment of Alzheimer's disease based on network pharmacology and molecular docking.
    Brain Res. 2025 May 22:149680. doi: 10.1016/j.brainres.2025.149680.
    PubMed     Abstract available


  35. SOLEIMANI Z, Davoudi S, Saffarzadeh F, Behzadi G, et al
    Restoring neuronal excitability and spatial memory through inhibiting amyloid-beta-induced hyperactive NF-kappaB in a rat model of Alzheimer's disease.
    Brain Res. 2025;1861:149703.
    PubMed     Abstract available


  36. KAUR J, Sharma V, Khan H, Singh S, et al
    Intersecting molecular pathways in Synucleinopathies and Amyloidogenesis: Exploring shared mechanisms and therapeutic potential.
    Brain Res. 2025;1855:149568.
    PubMed     Abstract available


  37. SHAHID F, Khan R, Mehmood A, Smadi AA, et al
    A comprehensive approach to anticipating the progression of mild cognitive impairment.
    Brain Res. 2025;1855:149549.
    PubMed     Abstract available


  38. XU C
    Enhanced social interaction protects cognition by preserving synapse numbers.
    Brain Res. 2025;1854:149552.
    PubMed     Abstract available


    April 2025
  39. MIYAZAKI H, Ide K, Yamaguchi H, Ogawa M, et al
    Peripheral lymphocyte counts and regional cerebral blood flow on brain SPECT correlate in Alzheimer's disease: A retrospective cross-sectional study.
    Brain Res. 2025;1859:149657.
    PubMed     Abstract available


  40. AHSAN R, Khan MM, Mishra A, Noor G, et al
    Plumbagin as a potential therapeutic agent for scopolamine-induced Alzheimer's disease: Mechanistic insights into GSK-3beta inhibition.
    Brain Res. 2025 Apr 16:149650. doi: 10.1016/j.brainres.2025.149650.
    PubMed     Abstract available


  41. FANG L, Fu X, Yu Y, Liu D, et al
    Collaborative multitasking framework for enhanced hippocampus segmentation and Alzheimer's disease classification.
    Brain Res. 2025;1858:149610.
    PubMed     Abstract available


  42. AKBARI F, Soheilian R, Tavalaeian S, Zamani A, et al
    Alterations in NFAT5 and ATP6V1E1 expression as potential diagnostic biomarkers in blood and brain for Alzheimer's disease: A study of gene overlap.
    Brain Res. 2025 Apr 3:149599. doi: 10.1016/j.brainres.2025.149599.
    PubMed     Abstract available


  43. RADBAKHSH S, Abrego-Guandique DM, Bacchetti T, Aghaee-Bakhtiari SH, et al
    Direct hybridization and bioinformatics analysis of circulating microRNAs in patients with Alzheimer's disease under intravenous trehalose treatment.
    Brain Res. 2025;1857:149607.
    PubMed     Abstract available


  44. CHIANG MC, Nicol CJB, Yang YP, Chiang T, et al
    The alpha-MG exhibits neuroprotective potential by reducing amyloid beta peptide-induced inflammation, oxidative stress, and tau aggregation in human neural stem cells.
    Brain Res. 2025;1852:149506.
    PubMed     Abstract available


    March 2025
  45. KARIM F, Ngo A, Danh TB, Delaney BA, et al
    Reduction in [(18)F]Nifene Binding, a PET imaging Probe for alpha4beta2* Nicotinic acetylcholinergic receptors in Hippocampus-Subiculum of postmortem human Alzheimer's disease brain.
    Brain Res. 2025;1857:149600.
    PubMed     Abstract available


  46. KAZEMI M, Sanati M, Shekari Khaniani M, Ghafouri-Fard S, et al
    A review on the lncRNA-miRNA-mRNA regulatory networks involved in inflammatory processes in Alzheimer's disease.
    Brain Res. 2025;1856:149595.
    PubMed     Abstract available


  47. JAIN S, Murmu A, Chauhan A
    Advancing Alzheimer's disease therapy through engineered exosomal Macromolecules.
    Brain Res. 2025;1855:149590.
    PubMed     Abstract available


  48. PINKY, Anwar S, Neha, Parvez S, et al
    Paeoniflorin inhibits pyruvate dehydrogenase kinase 3 and promotes BDNF activity by modulating neuronal activity and TNF-alpha.
    Brain Res. 2025;1851:149476.
    PubMed     Abstract available


  49. ABDEL-AAL RA, Meligy FY, Maghraby N, Sayed N, et al
    Comparing levetiracetam and zonisamide effects on rivastigmine anti-Alzheimer's activity in aluminum chloride-induced Alzheimer's-like disease in rats: Impact on alpha7 nicotinic acetylcholine receptors and amyloid beta.
    Brain Res. 2025;1855:149573.
    PubMed     Abstract available


  50. ZHENG C, Zhao Y, Hu C, Zhang L, et al
    Transcriptomic and network analysis identifies shared pathways across Alzheimer's disease and vascular dementia.
    Brain Res. 2025 Mar 3:149548. doi: 10.1016/j.brainres.2025.149548.
    PubMed     Abstract available


  51. DERAFSHPOUR L, Niazi M, Pourheydar B, Roshan-Milani S, et al
    Aging and voluntary exercise's effects on Abeta1-42 levels, endoplasmic reticulum stress factors, and apoptosis in the hippocampus of old male rats.
    Brain Res. 2025;1850:149447.
    PubMed     Abstract available


  52. GUTIERRE RC, Rocha PR, Graciani AL, Coppi AA, et al
    Tau, amyloid, iron, oligodendrocytes ferroptosis, and inflammaging in the hippocampal formation of aged rats submitted to an aerobic exercise program.
    Brain Res. 2025;1850:149419.
    PubMed     Abstract available


  53. WANG R, Azad AK, Sheikh AM, Tabassum S, et al
    Carboxylated Zn-phthalocyanine attenuates brain Abeta in AD model mouse.
    Brain Res. 2025;1850:149422.
    PubMed     Abstract available


    February 2025
  54. GHADGE SR, Shimpi PH, Kumbhar VV, Khairnar B, et al
    Comprehensive evaluation of AChE inhibition by Eulophia ochreata extract Utilizing in Silico, ex Vivo, and in vivo zebrafish models.
    Brain Res. 2025 Feb 24:149531. doi: 10.1016/j.brainres.2025.149531.
    PubMed     Abstract available


  55. TIAN Y, Li W, Zhang Y
    3-N-Butylphthalide alleviate Abeta-induced cellular senescence through the CDK2-pRB1-Caspase3 axis.
    Brain Res. 2025;1849:149435.
    PubMed     Abstract available


  56. WANG L, Li W, Wu W, Liu Q, et al
    Effects of electroacupuncture on microglia phenotype and epigenetic modulation of C/EBPbeta in SAMP8 mice.
    Brain Res. 2025;1849:149339.
    PubMed     Abstract available


  57. ZHAO X, Zhou Q, Zhang H, Ono M, et al
    Olfactory deprivation promotes amyloid beta deposition in a mouse model of Alzheimer's disease.
    Brain Res. 2025;1851:149500.
    PubMed     Abstract available


  58. DHAPOLA R, Kumari S, Sharma P, Vellingiri B, et al
    Advancements in autophagy perturbations in Alzheimer's disease: Molecular aspects and therapeutics.
    Brain Res. 2025;1851:149494.
    PubMed     Abstract available


    January 2025
  59. LI W, Yong-Yan X, Jia-Xin M, Shu-Chao G, et al
    Senescent microglia: The hidden culprits accelerating Alzheimer's disease.
    Brain Res. 2025 Jan 28:149480. doi: 10.1016/j.brainres.2025.149480.
    PubMed     Abstract available


  60. CHIARINI A, Armato U, Gui L, Yin M, et al
    Early divergent modulation of NLRP2's and NLRP3's inflammasome sensors vs. AIM2's one by signals from Abeta.Calcium-sensing receptor complexes in human astrocytes.
    Brain Res. 2025;1846:149283.
    PubMed     Abstract available


    December 2024
  61. ZHANG Z, Zhang S, Liu S, He Y, et al
    Fuzhisan ameliorates cognitive ability in Alzheimer's disease by p62 and related autophagy regulatory pathways.
    Brain Res. 2024;1849:149436.
    PubMed     Abstract available


  62. YANG Q, Chen T, Li S, Yang C, et al
    Inhibition of autophagy attenuates cognitive decline and mitochondrial dysfunction in an Alzheimer's disease mouse model with chronic cerebral hypoperfusion.
    Brain Res. 2024;1850:149416.
    PubMed     Abstract available


  63. XIE Y, Yang M, Wang H, Chen Y, et al
    Potential molecular mechanisms of tobacco smoke exposure in Alzheimer's disease.
    Brain Res. 2024;1848:149394.
    PubMed     Abstract available


  64. CHEN J, Zhang M, Shen Z, Tang M, et al
    Low-dose diazepam improves cognitive function in APP/PS1 mouse models: Involvement of AMPA receptors.
    Brain Res. 2024;1845:149207.
    PubMed     Abstract available


  65. DE SOUSA RAL, Mendes BF
    T-regulatory cells and extracellular vesicles in Alzheimer's disease: New therapeutic concepts and hypotheses.
    Brain Res. 2024;1850:149393.
    PubMed     Abstract available


  66. SUN S, Cui C, Li Y, Meng Y, et al
    A Machine learning classification framework using fused fractal property feature vectors for Alzheimer's disease diagnosis.
    Brain Res. 2024 Dec 3:149373. doi: 10.1016/j.brainres.2024.149373.
    PubMed     Abstract available


    November 2024
  67. CHEN Z, Zheng N, Wang F, Zhou Q, et al
    The role of ferritinophagy and ferroptosis in Alzheimer's disease.
    Brain Res. 2024 Nov 23:149340. doi: 10.1016/j.brainres.2024.149340.
    PubMed     Abstract available


  68. LIN L, Li J, Yu Z, He J, et al
    Nrf2 activator tertiary butylhydroquinone enhances neural stem cell differentiation and implantation in Alzheimer's disease by boosting mitochondrial function.
    Brain Res. 2024 Nov 18:149341. doi: 10.1016/j.brainres.2024.149341.
    PubMed     Abstract available


  69. PATTANAIK S, Prusty SK, Sahu PK
    Exploring DPP IV inhibitors for Alzheimer's disease: Bridging diabetes and neurodegeneration.
    Brain Res. 2024 Nov 18:149342. doi: 10.1016/j.brainres.2024.149342.
    PubMed     Abstract available


  70. MAHMUD JOY MA, Nasrin S, Siddiqua A, Farid DM, et al
    ViTAD: Leveraging Modified Vision Transformer for Alzheimer's Disease Multi-Stage Classification from Brain MRI Scans.
    Brain Res. 2024 Nov 11:149302. doi: 10.1016/j.brainres.2024.149302.
    PubMed     Abstract available


  71. ZHANG T, Yang J, Xu H, Cao Y, et al
    Acorus tatarinowii alleviates D-galactose-induced Alzheimer's-like disease cognitive impairment and Abeta-induced pericytes dysfunction in mice.
    Brain Res. 2024 Nov 6:149312. doi: 10.1016/j.brainres.2024.149312.
    PubMed     Abstract available


  72. DING X, Liu F, Wang H, Wang Y, et al
    Ganoderic acid a decreased Abeta42-induced neurotoxicity in PC12 cells by reduced mitochondrial damage.
    Brain Res. 2024;1842:149102.
    PubMed     Abstract available


  73. DIVYA R, Shantha Selva Kumari R
    Multi-instance learning attention model for amyloid quantification of brain sub regions in longitudinal cognitive decline.
    Brain Res. 2024;1842:149103.
    PubMed     Abstract available


    October 2024
  74. SEREBROVSKA Z, Xi L, Fedoriuk M, Dosenko V, et al
    Intermittent hypoxia-hyperoxia training ameliorates cognitive impairment and neuroinflammation in a rat model of Alzheimer's disease.
    Brain Res. 2024 Oct 28:149301. doi: 10.1016/j.brainres.2024.149301.
    PubMed     Abstract available


  75. GANESH A, Choudhury W, Coutellier L
    Early spatial recognition memory deficits in 5XFAD female mice are associated with disruption of prefrontal parvalbumin neurons.
    Brain Res. 2024;1841:149122.
    PubMed     Abstract available


  76. XIA N, Xu L, Xu D, Huang M, et al
    Neuroprotective effect of emodin on Abeta(25-35)-induced cytotoxicity in PC12 cells involves Nrf2/GPX4 and TLR4/p-NF-kappaB/NLRP3 pathways.
    Brain Res. 2024;1841:149019.
    PubMed     Abstract available


  77. MAFTOON H, Davar Siadat S, Tarashi S, Soroush E, et al
    Ameliorative effects of Akkermansia muciniphila on anxiety-like behavior and cognitive deficits in a rat model of Alzheimer's disease.
    Brain Res. 2024 Oct 15:149280. doi: 10.1016/j.brainres.2024.149280.
    PubMed     Abstract available


  78. PARKER J, Moris JM, Goodman LC, Paidisetty VK, et al
    A multifactorial lens on risk factors promoting the progression of Alzheimer's disease.
    Brain Res. 2024;1846:149262.
    PubMed     Abstract available


    September 2024
  79. ASADIFARD E, Hokmabadi M, Hashemi M, Bereimipour A, et al
    Linking gut microbiota dysbiosis to molecular pathways in Alzheimer's disease.
    Brain Res. 2024 Sep 16:149242. doi: 10.1016/j.brainres.2024.149242.
    PubMed     Abstract available


  80. WANG W, Xia H
    The role of lipid species in Alzheimer's disease onset: A comprehensive Mendelian randomization analysis.
    Brain Res. 2024 Sep 13:149238. doi: 10.1016/j.brainres.2024.149238.
    PubMed     Abstract available


  81. HAN R, Zhang X, Chen Y, Hou X, et al
    Associations between differential connectivity patterns of executive control networks and APOE varepsilon4 in the Alzheimer continuum.
    Brain Res. 2024 Sep 8:149229. doi: 10.1016/j.brainres.2024.149229.
    PubMed     Abstract available


    August 2024
  82. THAPA R, Ahmad Bhat A, Shahwan M, Ali H, et al
    Proteostasis disruption and senescence in Alzheimer's disease pathways to neurodegeneration.
    Brain Res. 2024;1845:149202.
    PubMed     Abstract available


  83. ZHANG QX, Zhang LJ, Zhao N, Yang L, et al
    Irisin in ischemic Stroke, Alzheimer's disease and Depression: A narrative review.
    Brain Res. 2024 Aug 28:149192. doi: 10.1016/j.brainres.2024.149192.
    PubMed     Abstract available


  84. SINGH M, Ali H, Renuka Jyothi S, Kaur I, et al
    Tau proteins and senescent Cells: Targeting aging pathways in Alzheimer's disease.
    Brain Res. 2024;1844:149165.
    PubMed     Abstract available


  85. ZHONG F, Xiong L, Wu J, Chen Y, et al
    The KEAP1/PGAM5/AIFM1-Mediated oxeiptosis pathway in Alzheimer's disease.
    Brain Res. 2024 Aug 19:149173. doi: 10.1016/j.brainres.2024.149173.
    PubMed     Abstract available


  86. BREEZE B, Connell E, Wileman T, Muller M, et al
    Menopause and Alzheimer's disease susceptibility: Exploring the potential mechanisms.
    Brain Res. 2024 Aug 18:149170. doi: 10.1016/j.brainres.2024.149170.
    PubMed     Abstract available


  87. MCCLARTY BM, Rodriguez G, Dong H
    Class 1 histone deacetylases differentially modulate memory and synaptic genes in a spatial and temporal manner in aged and APP/PS1 mice.
    Brain Res. 2024;1837:148951.
    PubMed     Abstract available


    July 2024
  88. SMITH T, Knudsen KJ, Ritchie SA
    A novel inducible animal model for studying chronic plasmalogen deficiency associated with Alzheimer's disease.
    Brain Res. 2024 Jul 23:149132. doi: 10.1016/j.brainres.2024.149132.
    PubMed     Abstract available


  89. ABUDUAINI Y, Chen W, Kong XZ
    Handedness in Alzheimer's disease: A systematic review.
    Brain Res. 2024 Jul 23:149131. doi: 10.1016/j.brainres.2024.149131.
    PubMed     Abstract available


    June 2024
  90. SUN S, Lu W, Zhang C, Wang G, et al
    Folic acid and S-adenosylmethionine reverse Homocysteine-induced Alzheimer's disease-like pathological changes in rat hippocampus by modulating PS1 and PP2A methylation levels.
    Brain Res. 2024 Jun 23:149095. doi: 10.1016/j.brainres.2024.149095.
    PubMed     Abstract available


  91. DE LOURDES SIGNORINI-SOUZA I, Tureck LV, Batistela MS, Coutinho de Almeida R, et al
    The potential of five c-miRNAs as serum biomarkers for Late-Onset Alzheimer's disease diagnosis: miR-10a-5p, miR-29b-2-5p, miR-125a-5p, miR-342-3p, and miR-708-5p.
    Brain Res. 2024 Jun 14:149090. doi: 10.1016/j.brainres.2024.149090.
    PubMed     Abstract available


  92. RUSSO ML, Ayala G, Neal D, Rogalsky AE, et al
    Alzheimer's-linked axonal changes accompany elevated antidromic action potential failure rate in aged mice.
    Brain Res. 2024 Jun 10:149083. doi: 10.1016/j.brainres.2024.149083.
    PubMed     Abstract available


  93. WANG Y, Wu LH, Hou F, Wang ZJ, et al
    Mitochondrial calcium uniporter knockdown in hippocampal neurons alleviates anxious and depressive behavior in the 3XTG Alzheimer's disease mouse model.
    Brain Res. 2024 Jun 6:149060. doi: 10.1016/j.brainres.2024.149060.
    PubMed     Abstract available


    May 2024
  94. FARHATULLAH, Chen X, Zeng D, Mehmood A, et al
    3-Way hybrid analysis using clinical and magnetic resonance imaging for early diagnosis of Alzheimer's disease.
    Brain Res. 2024 May 27:149021. doi: 10.1016/j.brainres.2024.149021.
    PubMed     Abstract available


  95. BHADANE P, Roul K, Belemkar S, Kumar D, et al
    Immunotherapeutic approaches for Alzheimer's disease: Exploring active and passive vaccine progress.
    Brain Res. 2024 May 21:149018. doi: 10.1016/j.brainres.2024.149018.
    PubMed     Abstract available


  96. ZHOU Q, Xu L
    The regulation of BAI1 in astrocytes through the STAT3/EZH2 axis relieves neuronal apoptosis in rats with Alzheimer's disease.
    Brain Res. 2024;1839:149007.
    PubMed     Abstract available


  97. LIU X, Chen J, Du Y, Tian Q, et al
    The changes of neurogenesis in the hippocampal dentate gyrus of SAMP8 mice and the effects of acupuncture and moxibustion.
    Brain Res. 2024;1831:148814.
    PubMed     Abstract available


  98. CHEN Y, Li Y, Wu M, Li Z, et al
    Electroacupuncture improves cognitive function in APP/PS1 mice by inhibiting oxidative stress related hippocampal neuronal ferroptosis.
    Brain Res. 2024;1831:148744.
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  99. FU Y, Xie GM, Liu RQ, Xie JL, et al
    From aberrant neurodevelopment to neurodegeneration: Insights into the hub gene associated with autism and alzheimer's disease.
    Brain Res. 2024;1838:148992.
    PubMed    


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    The microtubule-dynamin binding inhibitor peptide PHDP5 rescues spatial learning and memory deficits in Alzheimer's disease model mice.
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    Latest advances and clinical application prospects of resveratrol therapy for neurocognitive disorders.
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  102. HE R, Al-Tamimi J, Sanchez-Benavides G, Montana-Valverde G, et al
    Atypical cortical hierarchy in Abeta-positive older adults and its reflection in spontaneous speech.
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    April 2024
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    Investigating the effects of Thymus vulgaris essential oil, Allium cepa extract, and their active compounds (thymol and quercetin) on expression profile of genes related to Alzheimer's disease in PC12 model cell.
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  104. NEFODOVA A, Rudyk M, Dovhyi R, Dovbynchuk T, et al
    Systemic inflammation in Abeta(1-40)-induced Alzheimer's disease model: New translational opportunities.
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  105. XIE Y, Li X, Shi Q, Le L, et al
    The synergistic effect of curcumin and mitoquinol mesylate on cognitive impairment and the neuropathology of Alzheimer's disease.
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    Oxidative stress is associated with Abeta accumulation in chronic sleep deprivation model.
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    Altered metabolism and DAM-signatures in female brains and microglia with aging.
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    Palmatine improves cognitive dysfunction in Alzheimer's disease model rats through autophagy pathway and regulation of gut microbiota.
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    Disruption of sphingomyelin synthase 2 gene alleviates cognitive impairment in a mouse model of Alzheimer's disease.
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    Targeting VDAC: A potential therapeutic approach for mitochondrial dysfunction in Alzheimer's disease.
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    Alkaloids as drug leads in Alzheimer's treatment: Mechanistic and therapeutic insights.
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    Aurothioglucose encapsulated nanoparticles fostered neuroprotection in streptozotocin-induced Alzheimer's disease.
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    March 2024
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    Exploring the potential of quercetin in Alzheimer's Disease: Pharmacodynamics, Pharmacokinetics, and Nanodelivery systems.
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    Upregulation of NADPH-oxidase, inducible nitric oxide synthase and apoptosis in the hippocampus following impaired insulin signaling in the rats: Development of sporadic Alzheimer's disease.
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    Neuropsychiatric symptoms profile and markers of Alzheimer disease-type pathology in patients with Lewy body dementias.
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    Alleviation of behavioral deficits, amyloid-beta deposition, and mitochondrial structure damage associated with mitophagy upregulation in AD animal models via AAV9-IGF-1 treatment.
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    Study on multi-target effects of the novel HDAC6 inhibitor W5 on Abeta/Cu(2+)-induced Alzheimer's disease model of rats.
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    Amylovis-201 enhances physiological memory formation and rescues memory and hippocampal cell loss in a streptozotocin-induced Alzheimer's disease animal model.
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    February 2024
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    Chronic pain exacerbates memory impairment and pathology of Abeta and tau by upregulating IL-1beta and p-65 signaling in a mouse model of Alzheimer's disease.
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    Low-frequency rTMS modulated the excitability and high-frequency firing in hippocampal neurons of the Alzheimer's disease mouse model.
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  121. PUMO A, Legeay S
    The dichotomous activities of microglia: A potential driver for phenotypic heterogeneity in Alzheimer's disease.
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    The neurotransmitter puzzle of Alzheimer's: Dissecting mechanisms and exploring therapeutic horizons.
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    Could protein phosphatase 2A and glycogen synthase kinase-3 beta be targeted by natural compounds to ameliorate Alzheimer's pathologies?
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    January 2024
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    Sex-associated microRNAs potentially implicated in sporadic Alzheimer's disease (sAD).
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    Clinical and cortical trajectories in non-fluent primary progressive aphasia and Alzheimer's disease: A role for emotion processing.
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    Protective effect of scallop-derived plasmalogen against vascular dysfunction, via the pSTAT3/PIM1/NFATc1 axis, in a novel mouse model of Alzheimer's disease with cerebral hypoperfusion.
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    Improvement of spatial learning and memory deficits by intranasal administration of human olfactory ecto-mesenchymal stem cells in an Alzheimer's disease rat model.
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  129. BELVIRANLI M, Okudan N
    Coconut oil ameliorates behavioral and biochemical alterations induced by D-GAL/AlCl(3) in rats.
    Brain Res. 2024;1823:148704.
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  130. MAJOU D, Dermenghem AL
    Effects of DHA (omega-3 fatty acid) and estradiol on amyloid beta-peptide regulation in the brain.
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    Electroacupuncture ameliorates cognitive impairment in APP/PS1 mouse by modulating TFEB levels to relieve ALP dysfunction.
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    Robustly uncovering the heterogeneity of neurodegenerative disease by using data-driven subtyping in neuroimaging: A review.
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    Artificial sharp-wave-ripples to support memory and counter neurodegeneration.
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    December 2023
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    40 Hz Electroacupuncture relieves the memory dysfunction of 5xFAD mice by regulating neuronal electrical activity.
    Brain Res. 2023;1821:148576.
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    Genetic model of selective COX2 inhibition improve learning and memory ability and brain pathological changes in 5xFAD mouse.
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    Injection of exogenous amyloid-beta oligomers aggravated cognitive deficits, and activated necroptosis, in APP23 transgenic mice.
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    Asthma aggravates alzheimer's disease by up-regulating NF- kappaB signaling pathway through LTD4.
    Brain Res. 2023 Dec 11:148711. doi: 10.1016/j.brainres.2023.148711.
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    November 2023
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    Nicotinic acid modulates microglial TREM-2 gene in Phytohaemagglutinin-Induced in vitro model of Alzheimer's disease like pathology.
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    Gardenia jasminoides J. Ellis extract attenuates memory impairment in rats with Alzheimer's disease by suppressing NLRP3 inflammasome.
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    October 2023
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    A rat model established by simulating genetic-environmental interactions recapitulates human Alzheimer's disease pathology.
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    The effect of eight weeks of aerobic training with vitamin C on the expression pathway of antioxidants in the hippocampus tissue of TMT induced Alzheimer's disease rats.
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    Tight control of the APP-Mint1 interaction in regulating amyloid production.
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    Preparation and characterization of brain-targeted polymeric nanocarriers (Frankincense-PMBN-lactoferrin) and in-vivo evaluation on an Alzheimer's disease-like rat model induced by scopolamine.
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    Antioxidative and neuroprotective potential of Acorus calamus linn. and Cordia dichotoma G. Forst. In Alzheimer's type dementia in rodent.
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    September 2023
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    Dexmedetomidine mitigates neuroinflammation in an Alzheimer's disease mouse model via the miR-204-3p/FBXL7 signaling axis.
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    Alzheimer's disease: The role of T lymphocytes in neuroinflammation and neurodegeneration.
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  147. ARULCHELVAN E, Vanneste S
    Promising neurostimulation routes for targeting the hippocampus to improve episodic memory: A review.
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    August 2023
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    Identification of genes related to glucose metabolism and analysis of the immune characteristics in Alzheimer's disease.
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    Mitochondria transfer as a potential therapeutic mechanism in Alzheimer's disease-like pathology.
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    Astaxanthin enhances autophagy, amyloid beta clearance and exerts anti-inflammatory effects in in vitro models of Alzheimer's disease-related blood brain barrier dysfunction and inflammation.
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    Ketogenic diet alleviates brain iron deposition and cognitive dysfunction via Nrf2-mediated ferroptosis pathway in APP/PS1 mouse.
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    June 2023
  152. CHAVAN RS, Supalkar KV, Sadar SS, Vyawahare NS, et al
    ANIMAL MODELS OF ALZHEIMER'S DISEASE: AN ORIGINOF INNOVATIVETREATMENTS AND INSIGHT TO THE DISEASE'S ETIOLOGY.
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    Investigation of the protective effect of long-term exercise on molecular pathways and behaviours in scopolamine induced alzheimer's disease-like condition.
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    May 2023
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    Putative pathological mechanisms of late-life depression and Alzheimer's disease.
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    April 2023
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    An intracerebroventricular injection of ABeta (1-42) modifies temporal profiles of spatial memory performance and oxidative status in the temporal cortex rat.
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