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  Alzheimer's Disease

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Articles published in Brain Res

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    March 2020
  1. MAN J, Cui K, Fu X, Zhang D, et al
    Donepezil promotes neurogenesis via Src signaling pathway in a rat model of chronic cerebral hypoperfusion.
    Brain Res. 2020 Mar 14:146782. doi: 10.1016/j.brainres.2020.146782.
    PubMed     Abstract available


    February 2020
  2. CHEN WP, Cheng ZJ, Zhang G, Luo QH, et al
    EGb761 ameliorates cell necroptosis by attenuating RIP1-mediated mitochondrial dysfunction and ROS production in both in vivo and in vitro models of Alzheimer's disease.
    Brain Res. 2020 Feb 18:146730. doi: 10.1016/j.brainres.2020.146730.
    PubMed     Abstract available


    January 2020
  3. KRISHNAMURTHY K, Cantillana V, Wang H, Sullivan PM, et al
    ApoE mimetic improves pathology and memory in a model of Alzheimer's disease.
    Brain Res. 2020 Jan 30:146685. doi: 10.1016/j.brainres.2020.146685.
    PubMed     Abstract available


    December 2019
  4. IZZO J, Andreassen OA, Westlye LT, van der Meer D, et al
    The association between hippocampal subfield volumes in mild cognitive impairment and conversion to Alzheimer's disease.
    Brain Res. 2019 Dec 6:146591. doi: 10.1016/j.brainres.2019.146591.
    PubMed     Abstract available


    November 2019
  5. LIU Y, Zhong X, Shen J, Jiao L, et al
    Elevated serum TC and LDL-C levels in Alzheimer's disease and mild cognitive impairment: a meta-analysis study.
    Brain Res. 2019 Nov 22:146554. doi: 10.1016/j.brainres.2019.146554.
    PubMed     Abstract available


    October 2019
  6. REALE M, Gonzales-Portillo I, Borlongan CV
    Saliva, an easily accessible fluid as diagnostic tool and potent stem cell source for Alzheimer's Disease: present and future applications.
    Brain Res. 2019 Oct 25:146535. doi: 10.1016/j.brainres.2019.146535.
    PubMed     Abstract available


    September 2019
  7. VOULGAROPOULOU SD, van Amelsvoort TAMJ, Prickaerts J, Vingerhoets C, et al
    The effect of curcumin on cognition in Alzheimer's disease and healthy aging: A systematic review of pre-clinical and clinical studies.
    Brain Res. 2019 Sep 24:146476. doi: 10.1016/j.brainres.2019.146476.
    PubMed     Abstract available


    August 2019
  8. KHAN N, Haughey NJ, Nath A, Geiger JD, et al
    Involvement of organelles and inter-organellar signaling in the pathogenesis of HIV-1 associated neurocognitive disorder and Alzheimer's disease.
    Brain Res. 2019 Aug 16:146389. doi: 10.1016/j.brainres.2019.146389.
    PubMed     Abstract available


  9. SHANG J, Yamashita T, Tian F, Li X, et al
    Chronic cerebral hypoperfusion alters amyloid-beta transport related proteins in the cortical blood vessels of Alzheimer's disease model mouse.
    Brain Res. 2019 Aug 12:146379. doi: 10.1016/j.brainres.2019.146379.
    PubMed     Abstract available


    July 2019
  10. GIACOMELI R, Cristina Izoton J, Bem Dos Santos R, Peterini Boeira S, et al
    Neuroprotective effects of curcumin lipid-core nanocapsules in a model Alzheimer's disease induced by beta-amyloid 1-42 peptide in aged female mice.
    Brain Res. 2019 Jul 17:146325. doi: 10.1016/j.brainres.2019.146325.
    PubMed     Abstract available


  11. SARKAR S, Engler-Chiurazzi EB, Cavendish JZ, Povroznik JM, et al
    Over-expression of miR-34a Induces Rapid Cognitive Impairment and Alzheimer's Disease-like Pathology.
    Brain Res. 2019 Jul 8:146327. doi: 10.1016/j.brainres.2019.146327.
    PubMed     Abstract available


    June 2019
  12. CHEN J, Huang Y, Zhu C, Li Q, et al
    Early detection of Alzheimer's disease by peptides from phage display screening.
    Brain Res. 2019 Jun 24:146306. doi: 10.1016/j.brainres.2019.146306.
    PubMed     Abstract available


  13. SANFILIPPO C, Castrogiovanni P, Imbesi R, Kazakowa M, et al
    Sex Difference in CHI3L1 Expression Levels in Human Brain Aging and in Alzheimer's Disease.
    Brain Res. 2019 Jun 24:146305. doi: 10.1016/j.brainres.2019.146305.
    PubMed     Abstract available


  14. PIRAS IS, Krate J, Delvaux E, Nolz J, et al
    Association of AEBP1 and NRN1 RNA expression with Alzheimer's disease and neurofibrillary tangle density in middle temporal gyrus.
    Brain Res. 2019;1719:217-224.
    PubMed     Abstract available


    May 2019
  15. TORO CA, Zhang L, Cao J, Cai D, et al
    Sex Differences in Alzheimer's Disease: Understanding the Molecular Impact.
    Brain Res. 2019 May 23. pii: S0006-8993(19)30286.
    PubMed     Abstract available


  16. SUI Y, Zhang Y, Dong C, Xu B, et al
    The small molecular CCR3 antagonist YM344031 attenuates neurodegenerative pathologies and improves learning and memory performance in a mouse model of Alzheimer's disease.
    Brain Res. 2019 May 20. pii: S0006-8993(19)30277.
    PubMed     Abstract available


  17. TIAN M, Lin X, Wu L, Lu J, et al
    Angiotensin II Triggers Autophagy and Apoptosis in PC12 Cell Line: An in vitro Alzheimer's Disease Model.
    Brain Res. 2019 May 2. pii: S0006-8993(19)30243.
    PubMed     Abstract available


    March 2019
  18. GALLINO D, Devenyi GA, Germann J, Guma E, et al
    Longitudinal assessment of the neuroanatomical consequences of deep brain stimulation: Application of fornical DBS in an Alzheimer's mouse model.
    Brain Res. 2019 Mar 26. pii: S0006-8993(19)30169.
    PubMed    


    January 2019
  19. VAN BOCKSTAELE EJ, Ross JA
    Catecholamine dysregulation and neurodegenerative disease: From molecular mechanisms to circuit dysfunction.
    Brain Res. 2019;1702:1-2.
    PubMed    


  20. ROSS JA, Reyes BAS, Van Bockstaele EJ
    Amyloid beta peptides, locus coeruleus-norepinephrine system and dense core vesicles.
    Brain Res. 2019;1702:46-53.
    PubMed     Abstract available


    December 2018
  21. HU W, Feng Z, Xu J, Jiang Z, et al
    Brain-derived neurotrophic factor modified human umbilical cord mesenchymal stem cells-derived cholinergic-like neurons improves spatial learning and memory ability in Alzheimer's disease rats.
    Brain Res. 2018 Dec 23. pii: S0006-8993(18)30660.
    PubMed     Abstract available


    November 2018
  22. GIOVANNETTI EA, Fuhrmann M
    Unsupervised excitation: GABAergic dysfunctions in Alzheimer's disease.
    Brain Res. 2018 Nov 29. pii: S0006-8993(18)30608.
    PubMed     Abstract available


    August 2018
  23. CHEN K, Gao T, Bai Z, Yuan Z, et al
    Circulating APP, NCAM and Abeta serve as biomarkers for Alzheimer's disease.
    Brain Res. 2018 Aug 14. pii: S0006-8993(18)30435.
    PubMed     Abstract available


  24. KOSS DJ, Dubini M, Buchanan H, Hull C, et al
    Distinctive temporal profiles of detergent-soluble and -insoluble tau and Abeta species in human Alzheimer's disease.
    Brain Res. 2018 Aug 10. pii: S0006-8993(18)30434.
    PubMed     Abstract available


  25. TULLOCH J, Leong L, Thomson Z, Chen S, et al
    Glia-specific APOE epigenetic changes in the Alzheimer's disease brain.
    Brain Res. 2018 Aug 3. pii: S0006-8993(18)30420.
    PubMed     Abstract available


  26. SHEN Z, Lei J, Li X, Wang Z, et al
    Multifaceted Assessment of the APP/PS1 Mouse Model for Alzheimer's disease: Applying MRS, DTI, and ASL.
    Brain Res. 2018 Aug 2. pii: S0006-8993(18)30415.
    PubMed     Abstract available


    July 2018
  27. MA XH, Duan WJ, Mo YS, Chen JL, et al
    Neuroprotective effect of paeoniflorin on okadaic acid-induced tau hyperphosphorylation via calpain/Akt/GSK-3beta pathway in SH-SY5Y cells.
    Brain Res. 2018;1690:1-11.
    PubMed     Abstract available


    June 2018
  28. FENG T, Yamashita T, Zhai Y, Shang J, et al
    Chronic cerebral hypoperfusion accelerates Alzheimer's disease pathology with the change of mitochondrial fission and fusion proteins expression in a novel mouse model.
    Brain Res. 2018 Jun 4. pii: S0006-8993(18)30330.
    PubMed     Abstract available


    April 2018
  29. LEE M, Ban JJ, Yang S, Im W, et al
    The exosome of adipose-derived stem cells reduces beta-amyloid pathology and apoptosis of neuronal cells derived from the transgenic mouse model of Alzheimer's disease.
    Brain Res. 2018 Apr 3. pii: S0006-8993(18)30177.
    PubMed     Abstract available


    February 2018
  30. MAJKUTEWICZ I, Kurowska E, Podlacha M, Myslinska D, et al
    Age-dependent effects of dimethyl fumarate on cognitive and neuropathological features in the streptozotocin-induced rat model of Alzheimer's disease.
    Brain Res. 2018 Feb 14. pii: S0006-8993(18)30080.
    PubMed     Abstract available


    January 2018
  31. GANNON M, Wang Q
    Complex Noradrenergic Dysfunction in Alzheimer's Disease: Low Norepinephrine Input is Not Always to Blame.
    Brain Res. 2018 Jan 4. pii: S0006-8993(18)30001.
    PubMed     Abstract available


  32. HUANG S, Tong H, Lei M, Zhou M, et al
    Astrocytic glutamatergic transporters are involved in Abeta-induced synaptic dysfunction.
    Brain Res. 2018;1678:129-137.
    PubMed     Abstract available


  33. MA Y, Ma B, Shang Y, Yin Q, et al
    Flavonoid-rich ethanol extract from the leaves of Diospyros kaki attenuates cognitive deficits, amyloid-beta production, oxidative stress, and neuroinflammation in APP/PS1 transgenic mice.
    Brain Res. 2018;1678:85-93.
    PubMed     Abstract available


  34. RIZZI L, Maria Portal M, Batista CEA, Missiaggia L, et al
    CSF Abeta1-42, but not p-Tau181, differentiates aMCI from SCI.
    Brain Res. 2018;1678:27-31.
    PubMed     Abstract available


    December 2017
  35. BRAUN D, Feinstein DL
    The locus coeruleus neuroprotective drug vindeburnol normalizes behavior in the 5xFAD transgenic mouse model of Alzheimer's disease.
    Brain Res. 2017 Dec 21. pii: S0006-8993(17)30563.
    PubMed     Abstract available


  36. SATOH A, Iijima KM
    Roles of tau pathology in the locus coeruleus (LC) in age-associated pathophysiology and Alzheimer's disease pathogenesis: Potential strategies to protect the LC against aging.
    Brain Res. 2017 Dec 21. pii: S0006-8993(17)30562.
    PubMed     Abstract available


    November 2017
  37. VOGELSANG P, Giil LM, Lund A, Vedeler CA, et al
    Reduced glucose transporter-1 in brain derived circulating endothelial cells in mild Alzheimer's disease patients.
    Brain Res. 2017 Nov 1. pii: S0006-8993(17)30493.
    PubMed     Abstract available


  38. PONNUSAMY R, McNerney W, Moghadam S, Salehi A, et al
    Assessing disease-modifying effects of norepinephrine in Down syndrome and Alzheimer's disease.
    Brain Res. 2017 Nov 1. pii: S0006-8993(17)30494.
    PubMed     Abstract available


    October 2017
  39. ZHAO Q, Lu H, Metmer H, Li WXY, et al
    Evaluating Functional Connectivity of Executive Control Network and Frontoparietal Network in Alzheimer's Disease.
    Brain Res. 2017 Oct 24. pii: S0006-8993(17)30483.
    PubMed     Abstract available


  40. LIU M, Jevtic S, Markham-Coultes K, Ellens NPK, et al
    Investigating the efficacy of a combination Abeta-targeted treatment in a mouse model of Alzheimer's disease.
    Brain Res. 2017 Oct 21. pii: S0006-8993(17)30473.
    PubMed     Abstract available


  41. CHIARAVALLOTI A, Barbagallo G, Ricci M, Martorana A, et al
    Brain metabolic correlates of CSF Tau protein in a large cohort of Alzheimer's disease patients: a CSF and FDG PET study.
    Brain Res. 2017 Oct 21. pii: S0006-8993(17)30474.
    PubMed     Abstract available


  42. TAI J, Liu W, Li Y, Li L, et al
    Neuroprotective effects of a Triple GLP-1/GIP/Glucagon receptor agonist in the APP/PS1 transgenic mouse model of Alzheimer's disease.
    Brain Res. 2017 Oct 16. pii: S0006-8993(17)30459.
    PubMed     Abstract available


  43. ZHAO J, Lu S, Yu H, Duan S, et al
    Baicalin and ginsenoside Rb1 promote the proliferation and differentiation of neural stem cells in Alzheimer's disease model rats.
    Brain Res. 2017 Oct 13. pii: S0006-8993(17)30443.
    PubMed     Abstract available


    September 2017
  44. REYES-MARIN KE, Nunez A
    Seizure susceptibility in the APP/PS1 mouse model of Alzheimer's disease and relationship with amyloid beta plaques.
    Brain Res. 2017 Sep 26. pii: S0006-8993(17)30423.
    PubMed     Abstract available


  45. JAGIRDAR R, Chin J
    Corticothalamic network dysfunction and Alzheimer's disease.
    Brain Res. 2017 Sep 14. pii: S0006-8993(17)30399.
    PubMed     Abstract available


    August 2017
  46. MENG Y, Ding L, Zhang HY, Yin WC, et al
    An Abeta3-10-KLH vaccine reduced Alzheimer's disease-like pathology and had a sustained effect in Tg-APPswe/PSEN1dE9 mice.
    Brain Res. 2017 Aug 2. pii: S0006-8993(17)30316.
    PubMed     Abstract available


    July 2017
  47. DEBAY DR, Reid GA, Macdonald IR, Mawko G, et al
    Butyrylcholinesterase-Knockout Reduces Fibrillar beta-amyloid and Conserves 18FDG Retention in 5XFAD Mouse Model of Alzheimer's Disease.
    Brain Res. 2017 Jul 17. pii: S0006-8993(17)30299.
    PubMed     Abstract available


    June 2017
  48. QU B, Gong Y, Gill JM, Kenney K, et al
    Heterozygous knockout of cytosolic phospholipase A2alpha attenuates Alzheimer's disease pathology in APP/PS1 transgenic mice.
    Brain Res. 2017 Jun 22. pii: S0006-8993(17)30269.
    PubMed     Abstract available


    May 2017
  49. FEI YL, Lv HJ, Li YB, Liu J, et al
    Tongxinluo improves cognition by decreasing beta-amyloid in spontaneous hypertensive rats.
    Brain Res. 2017;1663:151-160.
    PubMed     Abstract available


  50. LI LH, Tu QY, Deng XH, Xia J, et al
    Mutant presenilin2 promotes apoptosis through the p53/miR-34a axis in neuronal cells.
    Brain Res. 2017;1662:57-64.
    PubMed     Abstract available


    March 2017
  51. KLINGEBIEL M, Dinekov M, Kohler C
    Analysis of ribosomal protein S6 baseline phosphorylation and effect of tau pathology in the murine brain and human hippocampus.
    Brain Res. 2017;1659:121-135.
    PubMed     Abstract available


    February 2017
  52. LI L, Xue Z, Chen L, Chen X, et al
    Puerarin suppression of Abeta1-42-induced primary cortical neuron death is largely dependent on ERbeta.
    Brain Res. 2017;1657:87-94.
    PubMed     Abstract available


  53. LI L, Qin L, Lu HL, Li PJ, et al
    Methylene blue improves streptozotocin-induced memory deficit by restoring mitochondrial function in rats.
    Brain Res. 2017;1657:208-214.
    PubMed     Abstract available


  54. NAVIGATORE-FONZO L, Castro A, Pignataro V, Casais M, et al
    Daily rhythms of cognition-related factors are modified in an experimental model of alzheimer disease.
    Brain Res. 2017 Feb 2. pii: S0006-8993(17)30046.
    PubMed     Abstract available


    January 2017
  55. FANG X, Zhong X, Yu G, Shao S, et al
    Vascular protective effects of KLF2 on Abeta-induced toxicity: Implications for Alzheimer's disease.
    Brain Res. 2017 Jan 24. pii: S0006-8993(17)30006.
    PubMed     Abstract available


  56. HOSSEINI N, Alaei H, Reisi P, Radahmadi M, et al
    The effects of NBM- lesion on synaptic plasticity in rats.
    Brain Res. 2017;1655:122-127.
    PubMed     Abstract available


  57. JANG WY, Lee BR, Jeong J, Sung Y, et al
    Overexpression of serum amyloid a 1 induces depressive-like behavior in mice.
    Brain Res. 2017;1654.
    PubMed     Abstract available


    November 2016
  58. DUAN H, Jiang J, Xu J, Zhou H, et al
    Differences in Abeta brain networks in Alzheimer's disease and healthy controls.
    Brain Res. 2016 Nov 17. pii: S0006-8993(16)30775.
    PubMed     Abstract available


  59. TENTOLOURIS-PIPERAS V, Ryan NS, Thomas DL, Kinnunen KM, et al
    Brain imaging evidence of early involvement of subcortical regions in familial and sporadic Alzheimer's disease.
    Brain Res. 2016 Nov 12. pii: S0006-8993(16)30751.
    PubMed     Abstract available


    September 2016
  60. PADAYACHEE E, Zetterberg H, Portelius E, Boren J, et al
    Cerebrospinal fluid-induced retardation of amyloid beta aggregation correlates with Alzheimer's disease and the APOE epsilon4 allele.
    Brain Res. 2016 Sep 18. pii: S0006-8993(16)30651.
    PubMed     Abstract available


  61. ZHUANG S, Wang X, Wang HF, Li J, et al
    Angiotensin Converting Enzyme Serum Activities: Relationship with Alzheimer's disease.
    Brain Res. 2016 Sep 5. pii: S0006-8993(16)30611.
    PubMed     Abstract available


    March 2016
  62. WANG J, Li N, Ma J, Gu Z, et al
    Effects of an amyloid-beta 1-42 oligomers antibody screened from a phage display library in APP/PS1 transgenic mice.
    Brain Res. 2016;1635:169-79.
    PubMed     Abstract available


  63. PALLO SP, DiMaio J, Cook A, Nilsson B, et al
    Mechanisms of tau and Abeta-induced excitotoxicity.
    Brain Res. 2016;1634:119-31.
    PubMed     Abstract available


    February 2016
  64. HAYAMA T, Murakami K, Watanabe T, Maeda R, et al
    Single administration of a novel gamma-secretase modulator ameliorates cognitive dysfunction in aged C57BL/6J mice.
    Brain Res. 2016;1633:52-61.
    PubMed     Abstract available


    January 2016
  65. LIU C, Wu Y, Zha S, Liu M, et al
    Treatment effects of tanshinone IIA against intracerebroventricular streptozotocin induced memory deficits in mice.
    Brain Res. 2016;1631:137-46.
    PubMed     Abstract available


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