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  Alzheimer's Disease

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Articles published in Brain Res

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Single Articles


    February 2024
  1. ZHANG Z, Ding C, Fu R, Wang J, et al
    Low-frequency rTMS modulated the excitability and high-frequency firing in hippocampal neurons of the Alzheimer's disease mouse model.
    Brain Res. 2024 Feb 24:148822. doi: 10.1016/j.brainres.2024.148822.
    PubMed     Abstract available


  2. PUMO A, Legeay S
    The dichotomous activities of microglia: A potential driver for phenotypic heterogeneity in Alzheimer's disease.
    Brain Res. 2024 Feb 21:148817. doi: 10.1016/j.brainres.2024.148817.
    PubMed     Abstract available


  3. MANTELLATTO GRIGOLI M, Pelegrini LNC, Whelan R, Cominetti MR, et al
    Present and Future of Blood-Based Biomarkers of Alzheimer's Disease: Beyond the Classics.
    Brain Res. 2024;1830:148812.
    PubMed     Abstract available


  4. SHARMA M, Pal P, Gupta SK
    The neurotransmitter puzzle of Alzheimer's: Dissecting mechanisms and exploring therapeutic horizons.
    Brain Res. 2024;1829:148797.
    PubMed     Abstract available


  5. DHEVII MANOHARAN S, Abdul Hamid H, Fariesha Md Hashim N, Singh Cheema M, et al
    Could protein phosphatase 2A and glycogen synthase kinase-3 beta be targeted by natural compounds to ameliorate Alzheimer's pathologies?
    Brain Res. 2024 Feb 1:148793. doi: 10.1016/j.brainres.2024.148793.
    PubMed     Abstract available


    January 2024
  6. TSAMOU M, Roggen EL
    Sex-associated microRNAs potentially implicated in sporadic Alzheimer's disease (sAD).
    Brain Res. 2024 Jan 31:148791. doi: 10.1016/j.brainres.2024.148791.
    PubMed     Abstract available


  7. LANDIN-ROMERO R, Kumfor F, Ys Lee A, Leyton C, et al
    Clinical and cortical trajectories in non-fluent primary progressive aphasia and Alzheimer's disease: A role for emotion processing.
    Brain Res. 2024;1829:148777.
    PubMed     Abstract available


  8. ZHAI Y, Morihara R, Feng T, Hu X, et al
    Protective effect of scallop-derived plasmalogen against vascular dysfunction, via the pSTAT3/PIM1/NFATc1 axis, in a novel mouse model of Alzheimer's disease with cerebral hypoperfusion.
    Brain Res. 2024 Jan 23:148790. doi: 10.1016/j.brainres.2024.148790.
    PubMed     Abstract available


  9. VALIPOUR B, Simorgh S, Mirsalehi M, Moradi S, et al
    Improvement of spatial learning and memory deficits by intranasal administration of human olfactory ecto-mesenchymal stem cells in an Alzheimer's disease rat model.
    Brain Res. 2024;1828:148764.
    PubMed     Abstract available


  10. BELVIRANLI M, Okudan N
    Coconut oil ameliorates behavioral and biochemical alterations induced by D-GAL/AlCl(3) in rats.
    Brain Res. 2024;1823:148704.
    PubMed     Abstract available


  11. MAJOU D, Dermenghem AL
    Effects of DHA (omega-3 fatty acid) and estradiol on amyloid beta-peptide regulation in the brain.
    Brain Res. 2024;1823:148681.
    PubMed     Abstract available


  12. CHEN H, Yang X, Gao Y, Jiang H, et al
    Electroacupuncture ameliorates cognitive impairment in APP/PS1 mouse by modulating TFEB levels to relieve ALP dysfunction.
    Brain Res. 2024;1823:148683.
    PubMed     Abstract available


  13. CHEN P, Zhang S, Zhao K, Kang X, et al
    Robustly uncovering the heterogeneity of neurodegenerative disease by using data-driven subtyping in neuroimaging: A review.
    Brain Res. 2024;1823:148675.
    PubMed     Abstract available


  14. KEIL J, Kiiski H, Doherty L, Hernandez-Urbina V, et al
    Artificial sharp-wave-ripples to support memory and counter neurodegeneration.
    Brain Res. 2024;1822:148646.
    PubMed     Abstract available


    December 2023
  15. MIAO J, Liu X, Lan J
    40 Hz Electroacupuncture relieves the memory dysfunction of 5xFAD mice by regulating neuronal electrical activity.
    Brain Res. 2023;1821:148576.
    PubMed     Abstract available


  16. YANG Y, Wang J, Ni H, Ding H, et al
    Genetic model of selective COX2 inhibition improve learning and memory ability and brain pathological changes in 5xFAD mouse.
    Brain Res. 2023;1821:148566.
    PubMed     Abstract available


  17. YU H, Morihara R, Ota-Elliott R, Bian Z, et al
    Injection of exogenous amyloid-beta oligomers aggravated cognitive deficits, and activated necroptosis, in APP23 transgenic mice.
    Brain Res. 2023;1821:148565.
    PubMed     Abstract available


  18. WANG X, Gan W, Kang M, Lv C, et al
    Asthma aggravates alzheimer's disease by up-regulating NF- kappaB signaling pathway through LTD4.
    Brain Res. 2023 Dec 11:148711. doi: 10.1016/j.brainres.2023.148711.
    PubMed     Abstract available


    November 2023
  19. AMIR A, Shahid M, Farooq Khan S, Nisar U, et al
    Nicotinic acid modulates microglial TREM-2 gene in Phytohaemagglutinin-Induced in vitro model of Alzheimer's disease like pathology.
    Brain Res. 2023;1824:148686.
    PubMed     Abstract available


  20. WANG Y, Gong Q, Pan H, Wang X, et al
    Gardenia jasminoides J. Ellis extract attenuates memory impairment in rats with Alzheimer's disease by suppressing NLRP3 inflammasome.
    Brain Res. 2023;1824:148687.
    PubMed     Abstract available


    October 2023
  21. XIAOMEI L, Tianyuyi F, Erheng C, Li Y, et al
    A rat model established by simulating genetic-environmental interactions recapitulates human Alzheimer's disease pathology.
    Brain Res. 2023 Oct 31:148663. doi: 10.1016/j.brainres.2023.148663.
    PubMed     Abstract available


  22. HASHEMI SA, Ghadimi Z, Ghaedi H, Hashemi A, et al
    The effect of eight weeks of aerobic training with vitamin C on the expression pathway of antioxidants in the hippocampus tissue of TMT induced Alzheimer's disease rats.
    Brain Res. 2023 Oct 21:148645. doi: 10.1016/j.brainres.2023.148645.
    PubMed     Abstract available


  23. HENRY SM, Kistler SA, Lagani GD, Bartling CRO, et al
    Tight control of the APP-Mint1 interaction in regulating amyloid production.
    Brain Res. 2023;1817:148496.
    PubMed     Abstract available


  24. MOAZZAM F, Hatamian-Zarmi A, Ebrahimi Hosseinzadeh B, Khodagholi F, et al
    Preparation and characterization of brain-targeted polymeric nanocarriers (Frankincense-PMBN-lactoferrin) and in-vivo evaluation on an Alzheimer's disease-like rat model induced by scopolamine.
    Brain Res. 2023;1822:148622.
    PubMed     Abstract available


  25. MALIK R, Kalra S, Pooja, Singh G, et al
    Antioxidative and neuroprotective potential of Acorus calamus linn. and Cordia dichotoma G. Forst. In Alzheimer's type dementia in rodent.
    Brain Res. 2023 Oct 2:148616. doi: 10.1016/j.brainres.2023.148616.
    PubMed     Abstract available


    September 2023
  26. LIAN X, Zhang X, Chen W, Xue F, et al
    Dexmedetomidine mitigates neuroinflammation in an Alzheimer's disease mouse model via the miR-204-3p/FBXL7 signaling axis.
    Brain Res. 2023 Sep 29:148612. doi: 10.1016/j.brainres.2023.148612.
    PubMed     Abstract available


  27. ASAMU MO, Oladipo OO, Abayomi OA, Adebayo AA, et al
    Alzheimer's disease: The role of T lymphocytes in neuroinflammation and neurodegeneration.
    Brain Res. 2023 Sep 19:148589. doi: 10.1016/j.brainres.2023.148589.
    PubMed     Abstract available


  28. ARULCHELVAN E, Vanneste S
    Promising neurostimulation routes for targeting the hippocampus to improve episodic memory: A review.
    Brain Res. 2023;1815:148457.
    PubMed     Abstract available


    August 2023
  29. WANG Y, Shen Z, Wu H, Yu Z, et al
    Identification of genes related to glucose metabolism and analysis of the immune characteristics in Alzheimer's disease.
    Brain Res. 2023 Aug 22:148545. doi: 10.1016/j.brainres.2023.148545.
    PubMed     Abstract available


  30. MISHRA M, Raik S, Rattan V, Bhattacharyya S, et al
    Mitochondria transfer as a potential therapeutic mechanism in Alzheimer's disease-like pathology.
    Brain Res. 2023 Aug 22:148544. doi: 10.1016/j.brainres.2023.148544.
    PubMed    


  31. ADEKUNLE BABALOLA J, Lang M, George M, Stracke A, et al
    Astaxanthin enhances autophagy, amyloid beta clearance and exerts anti-inflammatory effects in in vitro models of Alzheimer's disease-related blood brain barrier dysfunction and inflammation.
    Brain Res. 2023 Aug 12:148518. doi: 10.1016/j.brainres.2023.148518.
    PubMed     Abstract available


  32. QIN Y, Bai D, Tang M, Zhang M, et al
    Ketogenic diet alleviates brain iron deposition and cognitive dysfunction via Nrf2-mediated ferroptosis pathway in APP/PS1 mouse.
    Brain Res. 2023;1812:148404.
    PubMed     Abstract available


    June 2023
  33. CHAVAN RS, Supalkar KV, Sadar SS, Vyawahare NS, et al
    ANIMAL MODELS OF ALZHEIMER'S DISEASE: AN ORIGINOF INNOVATIVETREATMENTS AND INSIGHT TO THE DISEASE'S ETIOLOGY.
    Brain Res. 2023 Jun 9:148449. doi: 10.1016/j.brainres.2023.148449.
    PubMed     Abstract available


  34. KOSE S, Kutlu MD, Kara S, Polat S, et al
    Investigation of the protective effect of long-term exercise on molecular pathways and behaviours in scopolamine induced alzheimer's disease-like condition.
    Brain Res. 2023 Jun 1:148429. doi: 10.1016/j.brainres.2023.148429.
    PubMed     Abstract available


    May 2023
  35. HASAN SMN, Clarke C, Strand T, Bambico FR, et al
    Putative pathological mechanisms of late-life depression and Alzheimer's disease.
    Brain Res. 2023;1813:148423.
    PubMed     Abstract available


    April 2023
  36. CORIA-LUCERO C, Castro A, Ledezma C, Leporatti J, et al
    An intracerebroventricular injection of ABeta (1-42) modifies temporal profiles of spatial memory performance and oxidative status in the temporal cortex rat.
    Brain Res. 2023;1804:148242.
    PubMed     Abstract available


    February 2023
  37. STELMASHOOK EV, Voronkov DN, Stavrovskaya AV, Novikova SV, et al
    Neuroprotective effects of methylene blue in streptozotocin-induced model of Alzheimer's disease.
    Brain Res. 2023;1805:148290.
    PubMed     Abstract available


    January 2023
  38. ROBERTA DE SOUZA MENDES KAWAMU, Ferreira Lima Mota I, Santos Vasconcelos A, Renata Mortari M, et al
    Challenges in the pharmacological treatment of patients under suspicion of chronic traumatic encephalopathy: A review.
    Brain Res. 2023;1799:148176.
    PubMed     Abstract available


  39. SHOREY CL, Mulla RT, Mielke JG
    The effects of synthetic glucocorticoid treatment for inflammatory disease on brain structure, function, and dementia outcomes: A systematic review.
    Brain Res. 2023;1798:148157.
    PubMed     Abstract available


    December 2022
  40. YU J, Wu D, Zhao Y, Guo L, et al
    Study on multi-target effects of PIMPC on Abeta/Cu(2+)-induced Alzheimer's disease model of rats.
    Brain Res. 2022;1802:148226.
    PubMed     Abstract available


  41. YANG Y, Zhang J, Yang C, Dong B, et al
    Sulforaphane attenuates microglia-mediated neuronal damage by down-regulating the ROS/autophagy/NLRP3 signal axis in fibrillar Abeta-activated microglia.
    Brain Res. 2022;1801:148206.
    PubMed     Abstract available


  42. HUMPHREY CM, Hooker JW 4th, Thapa M, Wilcox MJ, et al
    Synaptic Loss and Gliosis in the Nucleus Tractus Solitarii with Streptozotocin-Induced Alzheimer's Disease.
    Brain Res. 2022 Dec 12:148202. doi: 10.1016/j.brainres.2022.148202.
    PubMed     Abstract available


  43. AHSANUL HAQUE M, Omori N, Md Sheikh A, Yano S, et al
    Analysis of the time-dependent changes of phospholipids in the brain regions of a mouse model of Alzheimer's disease.
    Brain Res. 2022 Dec 5:148197. doi: 10.1016/j.brainres.2022.148197.
    PubMed     Abstract available


    November 2022
  44. SILVA SSL, Tureck LV, Souza LC, Hortega JVM, et al
    Animal model of Alzheimer's disease induced by streptozotocin: new insights about cholinergic pathway.
    Brain Res. 2022 Nov 24:148175. doi: 10.1016/j.brainres.2022.148175.
    PubMed     Abstract available


  45. JUNG Y, Lopez-Benitez J, Tognoni CM, Carreras I, et al
    Dysregulation of sphingosine-1-phosphate (S1P) and S1P receptor 1 signaling in the 5xFAD mouse model of Alzheimer's disease.
    Brain Res. 2022;1799:148171.
    PubMed     Abstract available


  46. COSTA AJ, Oliveira RB, Wachilewski P, Nishino MS, et al
    Membrane estrogen receptor ERalpha activation improves tau clearance via autophagy induction in a tauopathy cell model.
    Brain Res. 2022;1795:148079.
    PubMed     Abstract available


    October 2022
  47. ANSARI MA, Rao MS, Al-Jarallah A, Babiker FM, et al
    Early Time Course of Oxidative Stress in Hippocampal Synaptosomes and Cognitive Loss Following Impaired Insulin Signaling in Rats: Development of Sporadic Alzheimer's Disease.
    Brain Res. 2022 Oct 31:148134. doi: 10.1016/j.brainres.2022.148134.
    PubMed     Abstract available


  48. ZHU X, Zhang Z, Yang X, Qi L, et al
    Improvement of extraction from Hericium erinaceus on the gut-brain axis in AD-like mice.
    Brain Res. 2022;1793:148038.
    PubMed     Abstract available


    August 2022
  49. VINH TO X, Soni N, Medeiros R, Alateeq K, et al
    Traumatic brain injury alterations in the functional connectome are associated with neuroinflammation but not tau in a P30IL tauopathy mouse model.
    Brain Res. 2022;1789:147955.
    PubMed     Abstract available


  50. PARK J, Kim SH, Kim YJ, Kim H, et al
    Elevation of phospholipase C-beta1 expression by amyloid-beta facilitates calcium overload in neuronal cells.
    Brain Res. 2022;1788:147924.
    PubMed     Abstract available


    June 2022
  51. LI G, Liang R, Lian Y, Zhou Y, et al
    Circ_0002945 functions as a competing endogenous RNA to promote Abeta25-35-induced endoplasmic reticulum stress and apoptosis in SK-N-SH cells and human primary neurons.
    Brain Res. 2022;1785:147878.
    PubMed     Abstract available


  52. FU X, Liu J, Xie J, Chen G, et al
    Identification of potential therapeutic and diagnostic characteristics of Alzheimer disease by targeting the miR-132-3p/FOXO3a-PPM1F axis in APP/PS1 mice.
    Brain Res. 2022;1790:147983.
    PubMed     Abstract available


    March 2022
  53. TANG ZB, Chen HP, Zhong D, Song JH, et al
    LncRNA RMRP accelerates autophagy-mediated neurons apoptosis through miR-3142/TRIB3 signaling axis in Alzheimer's disease.
    Brain Res. 2022 Mar 15:147884. doi: 10.1016/j.brainres.2022.147884.
    PubMed     Abstract available


    October 2021
  54. ZHENG SN, Pan L, Liao AM, Hou YC, et al
    Wheat Embryo Globulin Nutrients Ameliorate D-galactose and Aluminum Chloride-Induced Cognitive Impairment in Rats.
    Brain Res. 2021 Oct 1:147672. doi: 10.1016/j.brainres.2021.147672.
    PubMed     Abstract available


  55. MOHLE L, Brackhan M, Bascunana P, Pahnke J, et al
    Dimethyl fumarate does not mitigate cognitive decline and beta-amyloidosis in female APPPS1 mice.
    Brain Res. 2021;1768:147579.
    PubMed     Abstract available


  56. PLOSKA A, Cieslik P, Siekierzycka A, Kalinowski L, et al
    Neurochemical changes underlying cognitive impairment in olfactory bulbectomized rats and the impact of the mGlu5-positive allosteric modulator CDPPB.
    Brain Res. 2021;1768:147577.
    PubMed     Abstract available


    August 2021
  57. KUBOTA T, Kirino Y
    Age-dependent impairment of memory and neurofibrillary tangle formation and clearance in a mouse model of tauopathy.
    Brain Res. 2021;1765:147496.
    PubMed     Abstract available


  58. MCCANN A, Aarsland D, Ueland PM, Solvang SH, et al
    Serum tyrosine is associated with better cognition in Lewy body dementia.
    Brain Res. 2021;1765:147481.
    PubMed     Abstract available


  59. WU L, Du Q, Wu C
    CircLPAR1/miR-212-3p/ZNF217 feedback loop promotes amyloid beta-induced neuronal injury in Alzheimer's Disease.
    Brain Res. 2021 Aug 14:147622. doi: 10.1016/j.brainres.2021.147622.
    PubMed     Abstract available


    June 2021
  60. BIAN Z, Yamashita T, Shi X, Feng T, et al
    Accelerated accumulation of fibrinogen peptide chains with Abeta deposition in Alzheimer's disease (AD) mice and human AD brains.
    Brain Res. 2021 Jun 28:147569. doi: 10.1016/j.brainres.2021.147569.
    PubMed     Abstract available


    May 2021
  61. AHMADI N, Hosseini MJ, Rostamizadeh K, Anoush M, et al
    Investigation of therapeutic effect of Curcumin alpha and beta Glucoside anomers against Alzheimer's disease by the nose to brain drug delivery.
    Brain Res. 2021 May 12:147517. doi: 10.1016/j.brainres.2021.147517.
    PubMed     Abstract available


  62. SHAO P
    MiR-216a-5p ameliorates learning-memory deficits and neuroinflammatory response of Alzheimer's disease mice via regulation of HMGB1/NF-kappaB signaling.
    Brain Res. 2021 May 3:147511. doi: 10.1016/j.brainres.2021.147511.
    PubMed     Abstract available


    April 2021
  63. PLANAS-FONTANEZ TM, Sainato DM, Sharma I, Dreyfus CF, et al
    Roles of astrocytes in response to aging, Alzheimer's Disease and Multiple Sclerosis.
    Brain Res. 2021 Apr 1:147464. doi: 10.1016/j.brainres.2021.147464.
    PubMed     Abstract available


    March 2021
  64. PAIROJANA T, Phasuk S, Suresh P, Huang SP, et al
    Age and Gender Differences for the Behavioral Phenotypes of 3xTg Alzheimer's Disease mice.
    Brain Res. 2021 Mar 19:147437. doi: 10.1016/j.brainres.2021.147437.
    PubMed     Abstract available


    February 2021
  65. LAI AY, Joo IL, Trivedi AU, Dorr A, et al
    Cerebrovascular damage after midlife transient hypertension in non-transgenic and Alzheimer's disease rats.
    Brain Res. 2021 Feb 11:147369. doi: 10.1016/j.brainres.2021.147369.
    PubMed     Abstract available


  66. AHMED TF, Ahmed A, Imtiaz F
    History in Perspective: How Alzheimer's Disease came to be where it is?
    Brain Res. 2021 Feb 3:147342. doi: 10.1016/j.brainres.2021.147342.
    PubMed     Abstract available


    January 2021
  67. OWENS LV, Benedetto A, Dawson N, Gaffney CJ, et al
    Gene therapy-mediated enhancement of protective protein expression for the treatment of Alzheimer's disease.
    Brain Res. 2021 Jan 7:147264. doi: 10.1016/j.brainres.2020.147264.
    PubMed     Abstract available


  68. TIWARI V, Mishra A, Singh S, Kumar Mishra S, et al
    Protriptyline improves spatial memory and reduces oxidative damage by regulating NFkappaB-BDNF/CREB signaling axis in streptozotocin-induced rat model of Alzheimer's disease.
    Brain Res. 2021 Jan 7:147261. doi: 10.1016/j.brainres.2020.147261.
    PubMed     Abstract available


  69. LIU M, Beckett T, Am Thomason L, Dorr A, et al
    Covert strokes prior to Alzheimer's disease onset accelerate peri-lesional pathology but not cognitive deficits in an inducible APP mouse model.
    Brain Res. 2021 Jan 4:147233. doi: 10.1016/j.brainres.2020.147233.
    PubMed     Abstract available


    September 2020
  70. BERRY AJ, Zubko O, Reeves SJ, Howard RJ, et al
    Endocannabinoid system alterations in Alzheimer's disease: a systematic review of human studies.
    Brain Res. 2020 Sep 24:147135. doi: 10.1016/j.brainres.2020.147135.
    PubMed     Abstract available


    January 2020
  71. PORTE B, Marguerit G, Thomasseau S, Paquet C, et al
    Dose-dependent neuroprotective effect of the JNK inhibitor Brimapitide in 5xFAD transgenic mice.
    Brain Res. 2020;1727:146587.
    PubMed     Abstract available


  72. HILDRE AS, Solvang SH, Aarsland D, Midtun O, et al
    Components of the choline oxidation pathway modify the association between the apolipoprotein epsilon4 gene variant and cognitive decline in patients with dementia.
    Brain Res. 2020;1726:146519.
    PubMed     Abstract available


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