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Articles published in J Neurosci

Retrieve available abstracts of 47 articles:
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Single Articles


    March 2019
  1. ALONI E, Oni-Biton E, Tsoory M, Moallem DH, et al
    Synaptopodin deficiency ameliorates symptoms in the 3xTg mouse model of Alzheimer's disease.
    J Neurosci. 2019 Mar 14. pii: JNEUROSCI.2920-18.2019.
    PubMed     Text format     Abstract available


    January 2019
  2. DE PINS B, Cifuentes-Diaz C, Thamila Farah A, Lopez-Molina L, et al
    Conditional BDNF delivery from astrocytes rescues memory deficits, spine density and synaptic properties in the 5xFAD mouse model of Alzheimer disease.
    J Neurosci. 2019 Jan 30. pii: JNEUROSCI.2121-18.2019.
    PubMed     Text format     Abstract available


  3. MELO HM
    Potential Effects of Aspirin on Lysosomal Biogenesis and Amyloid-beta Clearance: An Old Drug and Novel Insights in Alzheimer's Disease Therapy.
    J Neurosci. 2019;39:197-198.
    PubMed     Text format    


    December 2018
  4. SALAZAR SV, Cox TO, Lee S, Brody AH, et al
    Alzheimer's Disease Risk Factor Pyk2 Mediates Amyloid-beta Induced Synaptic Dysfunction and Loss.
    J Neurosci. 2018 Dec 5. pii: JNEUROSCI.1873-18.2018.
    PubMed     Text format     Abstract available


    October 2018
  5. CAMARA H, De-Souza EA
    beta-Amyloid Accumulation Slows Earlier than Expected in Preclinical Alzheimer's Disease Patients.
    J Neurosci. 2018;38:9123-9125.
    PubMed     Text format    


  6. RUSH T, Martinez-Hernandez J, Dollmeyer M, Lise Frandemiche M, et al
    Synaptotoxicity in Alzheimer's disease involved a dysregulation of actin cytoskeleton dynamics through cofilin 1 phosphorylation.
    J Neurosci. 2018 Oct 19. pii: JNEUROSCI.1409-18.2018.
    PubMed     Text format     Abstract available


    September 2018
  7. GWON Y, Kam TI, Kim SH, Song S, et al
    TOM1 regulates neuronal accumulation of amyloid-beta oligomers by FcgammaRIIb2 variant in Alzheimer's disease.
    J Neurosci. 2018 Sep 5. pii: JNEUROSCI.1996-17.2018.
    PubMed     Text format     Abstract available


    July 2018
  8. CHANDRA S, Jana M, Pahan K
    Aspirin induces Lysosomal biogenesis and attenuates Amyloid plaque pathology in a mouse model of Alzheimer's disease via PPARalpha.
    J Neurosci. 2018 Jul 2. pii: JNEUROSCI.0054-18.2018.
    PubMed     Text format     Abstract available


  9. WU L, Zhang X, Zhao L
    Human ApoE Isoforms Differentially Modulate Brain Glucose and Ketone Body Metabolism: Implications for Alzheimer's Disease Risk Reduction and Early Intervention.
    J Neurosci. 2018 Jul 2. pii: JNEUROSCI.2262-17.2018.
    PubMed     Text format     Abstract available


    June 2018
  10. SANJARI MOGHADDAM H, Aarabi MH
    Abeta-Mediated Dysregulation of F-Actin Nanoarchitecture Leads to Loss of Dendritic Spines and Alzheimer's Disease-Related Cognitive Impairments.
    J Neurosci. 2018;38:5840-5842.
    PubMed     Text format    


    March 2018
  11. RAJENDRAN L, Paolicelli RC
    Microglia-Mediated Synapse Loss in Alzheimer's Disease.
    J Neurosci. 2018;38:2911-2919.
    PubMed     Text format     Abstract available


  12. VANDERHEYDEN WM, Lim MM, Musiek ES, Gerstner JR, et al
    Alzheimer's Disease and Sleep-Wake Disturbances: Amyloid, Astrocytes, and Animal Models.
    J Neurosci. 2018;38:2901-2910.
    PubMed     Text format     Abstract available


    February 2018
  13. LIMA-FILHO RAS, Oliveira MM
    A Role for Cellular Prion Protein in Late-Onset Alzheimer's Disease: Evidence from Preclinical Studies.
    J Neurosci. 2018;38:2146-2148.
    PubMed     Text format    


    January 2018
  14. MUELLER MC, Baranowski BJ, Hayward GC
    New Insights on the Role of Residue 673 of APP in Alzheimer's Disease.
    J Neurosci. 2018;38:515-517.
    PubMed     Text format    


    December 2017
  15. PEERA KOMMADDI R, Das D, Karunakaran S, Nanguneri S, et al
    Abeta mediates F-actin disassembly in dendritic spines leading to cognitive deficits in Alzheimer's disease.
    J Neurosci. 2017 Dec 15. pii: JNEUROSCI.2127-17.2017.
    PubMed     Text format     Abstract available


  16. WANG Z, Jackson RJ, Hong W, Taylor WM, et al
    Human Brain-Derived Abeta Oligomers Bind to Synapses and Disrupt Synaptic Activity in a Manner That Requires APP.
    J Neurosci. 2017;37:11947-11966.
    PubMed     Text format     Abstract available


    November 2017
  17. VAN DIJKEN I, van der Vlag M, Flores Hernandez R, Ross A, et al
    Perspectives on Treatment of Alzheimer's Disease: A Closer Look into EphB2 Depletion.
    J Neurosci. 2017;37:11296-11297.
    PubMed     Text format    


  18. RAY A, Speese SD, Logan MA
    Glial Draper rescues Abeta toxicity in a Drosophila model of Alzheimer's Disease.
    J Neurosci. 2017 Nov 6. pii: 0862-17. doi: 10.1523/JNEUROSCI.0862-17.2017.
    PubMed     Text format     Abstract available


  19. PARENT MJ, Zimmer ER, Shin M, Kang MS, et al
    Multimodal imaging in rat model recapitulates Alzheimer's Disease biomarkers abnormalities.
    J Neurosci. 2017 Nov 2. pii: 1346-17. doi: 10.1523/JNEUROSCI.1346-17.2017.
    PubMed     Text format     Abstract available


    October 2017
  20. NAKAZATO R, Kawabe K, Yamada D, Ikeno S, et al
    Disruption of Bmal1 Impairs Blood-Brain Barrier Integrity via Pericyte Dysfunction.
    J Neurosci. 2017;37:10052-10062.
    PubMed     Text format     Abstract available


  21. BANKS RA, Gibbons GS, Kim B, Xu H, et al
    GFP-mutant human tau transgenic mice develop tauopathy following CNS injections of Alzheimer's brain-derived pathological tau or synthetic mutant human tau fibrils.
    J Neurosci. 2017 Oct 6. pii: 2393-17. doi: 10.1523/JNEUROSCI.2393-17.2017.
    PubMed     Text format     Abstract available


    August 2017
  22. SUSS P
    Remote Control: Impacts of Peripheral Tumor Necrosis Factor-Alpha on Alzheimer Disease-Related Pathology.
    J Neurosci. 2017;37:8045-8047.
    PubMed     Text format    


  23. SALAZAR SV, Gallardo C, Kaufman AC, Herber CS, et al
    Conditional Deletion of Prnp Rescues Behavioral and Synaptic Deficits after Disease Onset in Transgenic Alzheimer's Disease.
    J Neurosci. 2017 Aug 21. pii: 0722-17. doi: 10.1523/JNEUROSCI.0722-17.2017.
    PubMed     Text format     Abstract available


  24. LI Y, Chen Z, Gao Y, Pan G, et al
    Synaptic adhesion molecule Pcdh-gammaC5 mediates synaptic dysfunction in Alzheimer's disease.
    J Neurosci. 2017 Aug 21. pii: 1051-17. doi: 10.1523/JNEUROSCI.1051-17.2017.
    PubMed     Text format     Abstract available


  25. CAPRELLI MT
    Regulation of Synaptic Amyloid-beta Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
    J Neurosci. 2017;37:7291-7293.
    PubMed     Text format    


    June 2017
  26. SOMPOL P, Furman JL, Pleiss MM, Kraner SD, et al
    Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Abeta-Bearing Mice.
    J Neurosci. 2017;37:6132-6148.
    PubMed     Text format     Abstract available


  27. ZHANG S, Wang Z, Cai F, Zhang M, et al
    BACE1 cleavage site selection critical for amyloidogenesis and Alzheimer's pathogenesis.
    J Neurosci. 2017 Jun 16. pii: 0340-17. doi: 10.1523/JNEUROSCI.0340-17.2017.
    PubMed     Text format     Abstract available


  28. DINIZ LP, Tortelli V, Matias I, Morgado J, et al
    Astrocyte transforming growth factor beta 1 protects synapses against Abeta oligomers in Alzheimer's disease model.
    J Neurosci. 2017 Jun 12. pii: 3351-16. doi: 10.1523/JNEUROSCI.3351-16.2017.
    PubMed     Text format     Abstract available


    May 2017
  29. PAOURI E, Tzara O, Kartalou GI, Zenelak S, et al
    Peripheral Tumor Necrosis Factor-Alpha (TNF-alpha) Modulates Amyloid Pathology by Regulating Blood-Derived Immune Cells and Glial Response in the Brain of AD/TNF Transgenic Mice.
    J Neurosci. 2017;37:5155-5171.
    PubMed     Text format     Abstract available


  30. SELLES MC, Fortuna JTS, Santos LE
    Immunomodulation via Toll-like Receptor 9: An Adjunct Therapy Strategy against Alzheimer's Disease?
    J Neurosci. 2017;37:4864-4867.
    PubMed     Text format    


  31. ROYEA J, Zhang L, Tong XK, Hamel E, et al
    Angiotensin IV receptors mediate the cognitive and cerebrovascular benefits of losartan in a mouse model of Alzheimer's disease.
    J Neurosci. 2017 May 5. pii: 0329-17. doi: 10.1523/JNEUROSCI.0329-17.2017.
    PubMed     Text format     Abstract available


    April 2017
  32. GAMAGE KK, Kumar S
    Aducanumab Therapy Ameliorates Calcium Overload in a Mouse Model of Alzheimer's Disease.
    J Neurosci. 2017;37:4430-4432.
    PubMed     Text format    


  33. BAEK SH, Park SJ, In Jeong J, Hyun Kim S, et al
    Inhibition of Drp1 Ameliorates Synaptic Depression, Abeta Deposition and Cognitive Impairment in Alzheimer's Disease Model.
    J Neurosci. 2017 Apr 21. pii: 2385-16. doi: 10.1523/JNEUROSCI.2385-16.2017.
    PubMed     Text format     Abstract available


    March 2017
  34. GRATTON C, Yousef S, Aarts E, Wallace DL, et al
    Cholinergic, but not dopaminergic or noradrenergic, enhancement sharpens visual spatial perception in humans.
    J Neurosci. 2017 Mar 23. pii: 2405-16. doi: 10.1523/JNEUROSCI.2405-16.2017.
    PubMed     Text format     Abstract available


    February 2017
  35. YE X, Feng T, Tammineni P, Chang Q, et al
    Regulation of Synaptic Abeta Generation Through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
    J Neurosci. 2017 Feb 3. pii: 2851-16. doi: 10.1523/JNEUROSCI.2851-16.2017.
    PubMed     Text format     Abstract available


    January 2017
  36. ZHANG ZH, Wu QY, Zheng R, Chen C, et al
    Selenomethionine mitigates cognitive decline by targeting both tau hyperphosphorylation and autophagic clearance in an Alzheimer's disease mouse model.
    J Neurosci. 2017 Jan 30. pii: 3229-16. doi: 10.1523/JNEUROSCI.3229-16.2017.
    PubMed     Text format     Abstract available


  37. JAY TR, Hirsch AM, Broihier ML, Miller CM, et al
    Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease.
    J Neurosci. 2017;37:637-647.
    PubMed     Text format     Abstract available


  38. VIEIRA MN, Beckman D
    Training Microglia to Resist Alzheimer's Disease.
    J Neurosci. 2017;37:477-479.
    PubMed     Text format    


  39. DATTA D
    APP Modulates Abeta-Induced Activation of Microglia in Mouse Model of Alzheimer's Disease.
    J Neurosci. 2017;37:238-240.
    PubMed     Text format    


  40. YANG T, Li S, Xu H, Walsh DM, et al
    Large Soluble Oligomers of Amyloid beta-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate.
    J Neurosci. 2017;37:152-163.
    PubMed     Text format     Abstract available


    December 2016
  41. PRIETO GA, Trieu BH, Dang CT, Bilousova T, et al
    Pharmacological rescue of long-term potentiation in Alzheimer diseased synapses.
    J Neurosci. 2016 Dec 16. pii: 2774.
    PubMed     Text format     Abstract available


  42. JAY TR, Hirsch AM, Broihier ML, Miller CM, et al
    Disease progression-dependent effects of TREM2 deficiency in a mouse model of Alzheimer's disease.
    J Neurosci. 2016 Dec 9. pii: 2110.
    PubMed     Text format     Abstract available


    November 2016
  43. LEDO JH, Azevedo EP, Beckman D, Ribeiro FC, et al
    Cross Talk Between Brain Innate Immunity and Serotonin Signaling Underlies Depressive-Like Behavior Induced by Alzheimer's Amyloid-beta Oligomers in Mice.
    J Neurosci. 2016;36:12106-12116.
    PubMed     Text format     Abstract available


  44. SHI XD, Sun K, Hu R, Liu XY, et al
    Blocking the Interaction between EphB2 and ADDLs by a Small Peptide Rescues Impaired Synaptic Plasticity and Memory Deficits in a Mouse Model of Alzheimer's Disease.
    J Neurosci. 2016;36:11959-11973.
    PubMed     Text format     Abstract available


  45. ZHANG H, Sun S, Wu L, Pchitskaya E, et al
    Store-Operated Calcium Channel Complex in Postsynaptic Spines: A New Therapeutic Target for Alzheimer's Disease Treatment.
    J Neurosci. 2016;36:11837-11850.
    PubMed     Text format     Abstract available


    October 2016
  46. SHU S, Zhu H, Tang N, Chen W, et al
    Selective Degeneration of Entorhinal-CA1 Synapses in Alzheimer's Disease via Activation of DAPK1.
    J Neurosci. 2016;36:10843-10852.
    PubMed     Text format     Abstract available


    September 2016
  47. SAITO T, Matsuba Y, Yamazaki N, Hashimoto S, et al
    Calpain Activation in Alzheimer's Model Mice Is an Artifact of APP and Presenilin Overexpression.
    J Neurosci. 2016;36:9933-6.
    PubMed     Text format     Abstract available


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